Anti-ACTN2 monoclonal antibody, clone FQ3630Z (DCABH-9438) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Rabbit monoclonal to Sarcomeric Alpha

Antigen Description F- cross-linking which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.

Immunogen A synthetic peptide (the amino acid sequence is considered to be commercially sensitive) corresponding to residues on the N-terminus of human Sarcomeric Alpha Actinin

Isotype IgG

Source/Host Rabbit

Species Reactivity Mouse, Rat, Human

Clone FQ3630Z

Purity Tissue culture supernatant

Conjugate Unconjugated

Applications WB, IP, IHC-P

Positive Control Human skeletal muscle, rat heart and human heart lysates and human muscle tissue.

Format Liquid

Size 100 μl

Buffer pH: 7.40; Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA

Preservative 0.01% Sodium Azide

Storage Store at -20°C. Stable for 12 months at -20°C

GENE INFORMATION

Gene Name ACTN2 actinin, alpha 2 [ Homo sapiens ]

Official Symbol ACTN2

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Synonyms ACTN2; actinin, alpha 2; alpha-actinin-2; F-actin cross-linking protein; alpha-actinin skeletal muscle; CMD1AA;

Entrez Gene ID 88

Protein Refseq NP_001094

UniProt ID P35609

Chromosome Location 1q42-q43

Pathway Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem;

Function FATZ 1 binding; ZASP binding; actin binding; calcium ion binding; identical protein binding; integrin binding; ion channel binding; protein binding; protein dimerization activity; structural constituent of muscle; Z domain binding; titin binding; ti

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved