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A E S S S L T A E A C R C I yyyyN S M S E E H C C T N IO A October 2001 Vol. LXXX, No. 2 yyyyC N ¥ AMERI

Monthly Meeting Henry A. Hill Award to M. Simon; Eli M.Pearce, ACS President-Elect speaks

Book Review “Bold Science: Seven Scientists Who Are Changing Our World”, by Ted Anton

Meeting Report Chemical Education at German Universities by C. Bolm

Nucleus Buyers Guide Listing of Suppliers, Products, and Services Call for Papers Undergraduate Research Poster Session 223rd National Meeting of the Ameri- can Chemical Society Orlando, Florida, April 7Ð11, 2002 The ACS invites undergraduate students to submit abstracts of their research papers for presentation at the Under- graduate Research Poster Session (URPS), which will be part of the extensive programming for undergradu- ates at this national meeting. Submit your abstract electronically by November 15, 2001 to . Click on the CHED division and then NOTE TO PRINTER select the URPS site that is appropriate to the subject of your paper. Please fol- Mass Vac low the directions carefully. For further information, contact: LaTrease Garrison 2/3 page ad appears here American Chemical Society Undergraduate Programs Office 1155 Sixteenth Street, NW Washington, DC 20036 Tel: 800-227-5558, ext. 6166 Ad # MASS 455N eÐmail: [email protected] Paper ad to be stripped in Member by Saltus News The following will be honored at the Orlando ACS Meeting, April 9, 2002 David M. Lemal, Dartmouth, NH ACS Award for Creative Work in Fluorine Andrew G. Myers, Harvard Award for Creative Work in Synthetic Organic Chemistry Charles H. DePuy, U. of Colorado, Boulder, James Flack Norris Award for Physical Organic Chemistry (Sponsored by NESACS). James S. Panek, Boston University Arthur C. Cope Scholar Award Matthew D. Shair, Harvard Univ., Arthur C. Cope Young Scholar Award Our congratulations to these distin- guished .

2 The Nucleus October 2001 The Northeastern Section of the American Chemical Society, Inc. Office: Marilou Cashman, 23 Cottage St., Contents Natick, MA 01760. 1-800-872-2054 (Voice or FAX) or 508-653-6329. Monthly Meeting ______5 e-mail: [email protected] Henry A. Hill Award to M.S. Simon, 50-year members honored, ACS Pres.-Elect Any Section business may be conducted via the business office above. Eli M. Pearce speaks on "Chemistry’s Changing Face Mirrors America" NESACS Homepage: http://www.NESACS.org ACS Election ______7 Frank R. Gorga, Webmaster Washington, D.C. ACS Hotline: Statements from the two candidates for President-Elect: Wm. F. Carroll and Elsa 1-800-227-5558 Reichmanis Officers 2001 Chair: NESACS News______8, 9 Timothy B. Frigo Travel Grants to Undergraduates for the Orlando, FL ACS Meeting in April, Advanced Magnetics, Inc. 61 Mooney St., Cambridge, MA 02138 2002; National Chemistry Week events; recent government relations activities 617-497-2070x3007; [email protected] Chair-Elect: Meeting Report______10 Morton Z. Hoffman Chemistry Education at German Universities, by Prof. Carsten Bolm, Aachen Chemistry Department, Boston University Boston, MA 02215-2507; 617-353-2494 [email protected] New England Chemists ______12 Immediate Past Chair: Arthur C. Cope, by George B. Kauffman Doris Lewis Chemistry Dept., Suffolk University Book Review ______14 41 Temple St., Boston, MA 02114 617-573-8546; [email protected] “Bold Science: Seven Scientists Who Are Changing Our World”, by Ted Anton, Secretary: reviewed by Maryann C. Kenney Michael Singer Sigma RBI Council Meeting Report ______16 1 Strathmore Rd. Natick, MA 01760-2447 Reports by your Representatives at the Chicago ACS Meeting, August, 2001 781-994-0523; fax:781-994-0677 [email protected] Puzzle Column ______17 Treasurer: James Piper First Annual Nucleus Buyers Guide______18–24 Simmons College, 300 The Fenway A listing of companies, products and services Boston, MA 02115, 617-521-2722 Auditor: Dr. Eli M. Pearce, President-Elect of the ACS (photo: Am. Chem. Soc.) Anthony Rosner Cover: Archivist: December 2001 issue: October 19, 2001 Myron Simon Deadlines: 20 Somerset Rd. January 2002 issue: November 15, 2001 Newton, MA 02465; 617-332-5273 [email protected] Trustees: Esther A.H. Hopkins, Michael E. Strem, Joseph A. Lima Councilors: Alternate Councilors: Term ends 12/31/2001 Term ends 12/31/2001 Thomas R. Gilbert Michael P. Filosa The Nucleus is distributed to the members of the Northeastern Section of the American Chemical Michael J. Hearn Morton Z. Hoffman Society, to the secretaries of the Local Sections, and to editors of all local A.C.S. Section publications. Arlene Wick Light Donald O. Rickter Forms close for advertising on the 1st of the month of the preceding issue. Text must be received by the Michael Singer Sophia R. Su editor six weeks before the date of issue. Term Ends 12/31/2002 Term ends 12/31/2002 Editor: Arno Heyn, 21 Alexander Rd., Newton, MA 02461, Mary T. Burgess Michael J. Dube Michaeline F. Chen Jean Fuller-Stanley Tel: 617-969-5712, FAX: 617-527-2032; e-mail:[email protected] Doris I. Lewis Patrick M. Gordon Associate Editor: Myron S. Simon, 20 Somerset Rd., W. Newton, MA 02465, Tel: 617-332-5273 Julia H. Miwa John L. Neumeyer Board of Publications: Marietta H. Schwartz (Chair), Patrick M. Gordon, Frank R. Gorga, E. Joseph Term Ends 12/31/2003 Term ends 12/31/2003 Billo (Consultant) Catherine E. Costello Arno H.A. Heyn Business Manager: Karen Piper, 19 Mill Rd., Harvard, MA 01451, William Klemperer Wallace J. Gleekman Tel: 978-456-8622 Truman Light(to12/31/01)Alfred Viola Dororthy J. Phillips Derk A. Wierda Advertising Manager: Vincent J. Gale, P.O. Box 1150, Marshfield, MA 02050, Tel: 781-837-0424; FAX: 781-837-8792 All Chairs of standing Contributing Editors: Mukund Chorghade, Patricia Hamm, Features; Edward Atkinson, History of Committees, the editor Chemistry; Maryann Solstad, Health; Dennis Sardella, Book Reviews; Marietta H. of THE NUCLEUS, and Schwartz, Software Reviews; E. Joseph Billo, Puzzles. the Trustees of Section Calendar Coordinator: Donald O. Rickter, e-mail: [email protected] Funds are members of the Proofreaders: E. Joseph Billo, Donald O. Rickter, M.S. Simon Board of Directors. Any Webpage: Webmaster: Frank R. Gorga, [email protected] Councilor of the American Chemical Society Asst. Webmasters:Terry Brush, [email protected] residing within the section area is an ex officio Kurt Heinselman, [email protected] member of the Board of Directors. Copyright 2001, Northeastern Section of the American Chemical Society, Inc. The Nucleus October 2001 3 Corporate Patrons Directions Henry Aaron Alfa Aesar, a Johnson Matthey Com- From Rte. 30 Westbound pany A little over a mile from Rte. 128, at Hoechst Marion Roussel Co. the top of the hill, take a hairpin left Hill onto Oak St. (sign: Oak St. to Cliff Who was Henry A. Hill? Pharm-Eco Laboratories, Inc. Rd.). Follow the road 0.7 mile to a 4- Physical Sciences, Inc. Henry Hill was Chairman of our Sec- Polaroid Corporation way intersection. Go straight through, tion in 1963. He was very active in the Strem Chemicals, Inc. take second right onto Scotch Pine Rd.. national ACS, a member of and chair- Take first right (Westcliff Rd.). Hen- man of several of its committees. Corporate Sponsors derson House is the first house on the Especially notable was his service on Aerodyne Research, Inc. left side (#99). the Professional Relations Committee, AstraZeneca R&D From Mass Turnpike West where he drafted the Professional Borregaard Synthesis, Inc. Take exit 15 (Rte. 95/128). After toll Employment Guidelines. He was Bristol-Myers Squibb booth bear left, follow Rte. 30 West. Director of the ACS in 1971-1975 and Cambridge Isotope Labs Proceed as above. was elected President-Elect and Consulting Resources Corporation From Mass Turnpike East became President in 1976. Take Exit 14 (Rte. 95/128), follow sign Dike, Bronstein, Roberts & Born in St. Joseph, Missouri, he Cushman, LLP for Rte. 128 North, then stay right for obtained a bachelor's degree from exit to Rte. 30. Turn left. Following Houghton Chemical Corp. Johnson C. Smith University, then a JEOL, USA, Inc. Rte. 30 West. Proceed as above. segregated university for "colored" stu- MassTrace, Inc. From Rte. 9 West dents, as, they were then called. After crossing under Rte. 16, and after Because of his excellent record he was New England Biolabs the traffic light at the fire station, turn accepted at M.I.T., to study organic Organix, Inc. right just after the Gulf Station. Take chemistry, and obtained the Ph.D. in Pfizer, Inc. Cliff Rd. northbound (left). The sev- 1942, working under Prof. Robert C. Research Biochemicals Int’l enth road on the left is Scotch Pine Rd. Hockett. He had the highest grades of Zymark Corporation Turn left into this road, then the first the graduate students in his class. right, Westcliff Rd. Henderson House While at M.I.T. he became acquainted is the first house on the left, #99. with Prof. James Flack Norris of ness. In 1946 he joined Dewey & From Rte. 95/128 North or South whom he said: Almy Co. as Research Supervisor and Take exit 24 to Rte. 30 West (if south- He was the first big man I met in 1952 he became Vice President of bound on Rte. 128) or exit 20B to Rte. who was more interested in my ability National Polychemicals. He obtained 9 (if northbound on Rte. 128) and fol- to learn chemistry than in the identity patents for blowing agents. low directions for Rte. 30 West or Rte. of my grandparents In 1961 he established his own 9 West, respectively Not being able to obtain a position research and consulting business, Park in front of Henderson House, or in industry because of prevailing dis- "Riverside Laboratories", to be able to in the large parking area to its right. crimination, he and a few colleagues pursue his research interests and to Respect the privacy of neighbors, do established a small consulting busi- allow him to participate in ACS activi- not park in front of homes. ties. After his untimely death in 1979, friends and colleagues in the North- eastern Section established the Henry A. Hill Award for Outstanding Service to the Northeastern Section. The first award was made posthumously to Henry A. Hill in 1980, his son Anthony C. Hill, then a reporter for WGBH, accepting the award. Since then, 26 members of this section have been thus honored and thereby honored the memory of Henry A. Hill. From an appreciation of Henry A. Hill delivered at the 1991 Hill Award meeting and based on notes of the late Larry Powell.

4 The Nucleus October 2001 Abstract Monthly Meeting Chemistry’s Changing Face Celebrating the 125th Anniversary of the ACS Mirrors America The 827th Meeting of the Northeastern Section The changes in the composition of the of the American Chemical Society chemical workforce mirror the changes Thursday, October 11, 2001 in the U.S. population. In the last decade alone, women and minorities - Henderson House, 99 Westcliff Rd., Weston, MA African Americans, Asian Americans, 5:30 pm Social Hour; a table of Career Services Literature and Aids will be Latinos and Native Americans - have available become a significantly larger share of 6:30 pm Dinner the workforce. They are, however, 7:45 pm Evening Meeting, Dr. Timothy Frigo, Chair, presiding unevenly distributed across chemical specialties and economic sectors (gov- 50-year members honored; welcoming new members ernment, industry and academe). The Presentation of the Henry A. Hill Award for Outstanding Service to status of women, minorities and the the Northeastern Section to Dr.Myron S. Simon particular challenges they face will be Dr. Eli M. Pearce, President-Elect of the ACS speaks on Chemistry’s explored, along with present and Changing Face Mirrors America potential responses to the changing Dinner reservations should be made no later than noon, October 4. Please call or face of 21st century chemistry. fax Marilou Cashman at (800) 872-2054 or e-mail at [email protected]. Please specify chicken, fish, or vegetarian. Reservations not cancelled at least 24 hours in advance must be paid. Members, $25.00; Non-members, $28.00; Retirees, $15.00; Students, $ 8.00. polymers, and laboratory manuals. THE PUBLIC IS INVITED. He is a fellow of AAAS, AIC, Anyone who needs special services or transportation, please call Marilou NYAS, SPE, and NATAS and has been Cashman a few days in advance so that suitable arrangements can be made. very active in the American Chemical Free Parking at Henderson House Ð do not park in the street or driveway. Society, having been on, or chaired Next Meeting: Norris Award Meeting, November 8, 2001 at the Newton Holi- many of its committees and has been a day Inn, 399 Grove St., Newton, MA.. 5:30 pm Reception and dinner, Riverside Director-at-Large from 1999-2000. He Room; 7:45 pm Award Meeting. Awardee:Dr. Dennis Peters (Analytical Chem- has been elected to be the current Pres- istry), Indiana University, Bloomington, IN ident-Elect and is to be President of the ACS for 2002. He has also been active in numer- Department Head, Dean of Arts and ous national and international commit- Science, Director of the Polymer tees and societies. He has co-chaired Biography Research Institute and is presently two Gordon Conferences in his field. Dr. Eli M. Pearce, a Brooklyn native, University Research Professor. He has received a number of received a B.S. in 1949 (Brooklyn Col- His researches in polymer chem- awards, including the ACS Polymer lege), an M.S. from New York Univer- istry involved both theoretical and Division’s Distinguished Service sity, and a Ph.D. from Brooklyn practical aspects, with a special interest Award (1991), the P.J. Flory Polymer Polytechnic Institute, working with in flammability studies, and fluorine Education Award (1992), and most Prof. Charles G. Overberger on containing polymers, as well as funda- recently, the Oscar Riker Foster Award cationic and anionic polymerization. mental studies of the relationship of the Chemistry Teachers Club of In 1958 he joined DuPont, in 1962 between mixture components and the New York (2000). he became a Section Manager at J.T. physical and chemical properties of He lives with his wife Judith in Baker Co., and in 1968 a manager at resulting polymers. His researches East Hampton, NY. Allied Chemical Corp. In 1974 he was have resulted in over 250 papers and appointed Director of the Dreyfus Lab- four patents. oratory at Research Triangle Park, and Dr. Pearce has been the editor of shortly thereafter he joined the Poly- the Journal of Polymer Chemistry for technic University of New York as 25 years and is on the editorial board Professor of Chemistry. and Chemical of several polymer-related journals and Engineering. co-editor of six books dealing with At Polytech he has served as flammability, fibers, and the future of

The Nucleus October 2001 5 Chairman in 1984, Alter- nate Councillor, 1984-93, Henry A. Hill Trustee in 1987. He spon- Fifty-Year sored the Seaborg Pro- 2001 Awardee posal to end nuclear Members Myron S. Simon testing in 1985, which led To be honored at the October to a Presidential Debate at meeting The Henry A. Hill Award the ACS Chicago Meeting is given for “Outstanding that year. He proposed Dr. Robert Abeles Service to the Northeast- the Secondary School Waltham, MA ern Section.” This year's Teaching Prize, now Dr. John Buchannan awardee is Myron S. the Theodore William Cambridge, MA Simon, a long-standing Richards Award for Excel- Dr. Sherman L. Burson, Jr. member of the Section, lence in Teaching, and South Chatham, MA and for the last eight years Aula Laudis Society in Mr. Richard S. Cass its Archivist. 1985 to recognize superior Watertown, MA He obtained the A.B., M.A. and teaching at the high school level. Mr. Ernest J. Comeau, Jr., Ph.D. degrees at Harvard, the latter from He was a co-founder of the Esselen Hampton, NH Professor R.B.Woodward in 1949. He Award Committee and its member, Mr. Bennett S. Gesmer was a research scientist at Polaroid Cor- 1985-1993 and 1995-1999, and Chair- Waban, MA poration from 1949 to 1988, primarily man 1985-1988, 1991 and 1997. He Dr. Theodore W. Gilbert doing research in the field of instant chaired the Committee on Professional Nantucket, MA color photography, obtaining more than Relations 1987-92 and has been the Mr. Thomas J Giovanniello 70 U.S. patents, and retiring in 1988 as Associate Editor of the NUCLEUS since Milton, MA Research Fellow and Associate Director 1988. He was a member of the Centen- Dr. Martin Idelson of Organic Chemistry. He consulted as nial Committee in 1998. He chaired the West Newton, MA founder of Image-Ination Associates Tours Committee at the last two ACS Mr. Irving Isgur until 1996. National meetings in Boston, and was a Framingham, MA He was Chairman of the Section in member of the IUPAC Planning Com- Dr. Paul R. Jones 1985, Chairman-Elect and Program mittee for its Boston Meeting in 1987. Ann Arbor, MI Mr. Roger J. Labrie Plainville, MA Dr. Jack L. Lapuck Newton Center, MA Mr. Giuglio Lopolito Burlington, MA Mr. Robert H. Mc Cluer Houston, TX Dr. Jack Milgrom Maywood, NJ Mr. Arthur T. Nelson Scituate, MA Mrs. Betty H. Palm Lexington, MA Mr. Charles A. Rossiter Wellesley, MA Dr. Dietmar Seyferth Cambridge, MA Dr. Stephen J. Tauber Lexington, MA Dr. Grant Urry Winchester, MA Dr. Bert L. Vallee Boston, MA Our best wishes to these 50-year members.

6 The Nucleus October 2001 ACS Election Teachers’ Candidates for President-Elect have submitted the following. Conference Ballots will be mailed to members in October. Convergence of Chemistry and William F. Carroll, Jr. ACS’ value proposition. Tell me The Joint Meeting of New England where you see value and where you Section of the American Association Value Matters don’t. Together we can maximize it, and create more. of Physics Teachers (NESAPS) and My first priority: Value. Specifically, I the New England Section of the want to increase ACS’ value to mem- I value your participation in this American Physical Society bers. We create value by innovating to election, and respectfully ask for your address needs. Here are two examples: vote. In return, I commit to use my (NESAPS) ability and experience to bring value to ¥ Better continuing education materi- November 2-3, ACS members, to our Society and to als that help members anticipate, Keene State College society at large. adapt and grow into career changes, Because in the end, value matters. Presentations will include individual thus becoming more valuable within Please visit http://www.billcar- presentations, as well as workshops on their place of employment. roll.org for more information or to Integration of Physics And Chemistry ¥ Intensive teaching course and comment directly. with HS Math, The Physics of Chem- streamlined certification process for istry, Using Excel in the Physics Class- chemists with advanced degrees or room. There also will be roundtable experience desiring a career transi- Elsa Reichmanis discussions. tion to K-12 education. Planning Together Today to For information: We communicate value by listen- fits relevant and accessible. We The role that chemistry plays and will quantify value to verify when we’re continue to play in the development of successful and when improvement is innovative new technologies is issue of public outreach to both our needed. Evaluation and innovation expanding. From pharmaceuticals and local communities and our legislators. must be continuous. Our members biotechnology, to new high perform- The public image of chemistry needs have diverse backgrounds, ranks, posi- ance materials with unique properties, improvement. The general public must tions and needs, but value matters to an understanding of chemistry is be made aware that it was chemists all. imperative. For those of us in the and chemical engineers who developed My second priority: Outreach. field, keeping up with the latest break- new drug therapies that have revolu- The most visible representative of the throughs is critical. tionized modern medicine; and few Society must reach out to non-scien- As President of the ACS, I will individuals appreciate the important tists. As President, I will pursue speak- work to encourage programming that role chemistry has played in the devel- ing and listening opportunities with lay better addresses the current and future opment of electronic devices and dis- organizations at least twice a month. needs of chemists and chemical engi- plays. We are rightfully concerned about neers. I know that many chemists are I am aware of the Society’s efforts chemophobia, but we can be agents for unable to attend national meetings, and to reach out to legislators at both the “chemophilia” as well. the Local Section is their contact with federal and state levels. It is important Outreach and service components the ACS. I would like to work with to both continue these efforts and of National Chemistry Week, such as both the Local Sections and ACS increase the level of member involve- demonstrations for students and Career Services in presenting more ment. As President, I would like to teacher training, make members feel programs to help members expand strengthen support for these critically they “make a difference.” They value their skills to become better equipped important Local Section endeavors. that feeling. Taking on a service ethic to meet today’s dynamic employment If elected ACS President, I will as a scientific Society links chemistry environment. I believe that the chemi- emphasize that the most valuable and chemists with everyday life and cal workforce will be in a better posi- resource that the ACS has is its mem- ordinary people, for the betterment of tion to respond and react to change, bership. all. when it is prepared! For more information, please visit Expect your officers to focus on Also of prime importance is the www.elsareichmanis.net

The Nucleus October 2001 7 Grants-in-Aid to National Undergraduates Chemistry To attend the 223rd ACS National Meeting in Orlando, FL April 7-11, 2002 Week The Northeastern Section of the Amer- and the NESACS office. In addition, November 4-10, 2001 ican Chemical Society will provide application forms may be obtained Celebrating Chemistry and Art Grants-in Aid of $250 to each of four from the NESACS Web site at The theme is “Celebrating Chemistry undergraduates to enable them to http://www.nesacs.org. The deadline and Art”. The Northeastern Section is attend the 223rd ACS National Meet- for receipt of completed applications is planning two days of events: ing, and present a paper at the Under- November 1, 2001. Completed appli- Sunday, Nov. 4th, at the Museum of graduate Research Poster Session in cations are to be sent to: Science in Boston NESACS will fea- the Division of Chemical Education. Professor Ruth Tanner ture two presentations by Prof. Bassam The institutions of the successful appli- University of Massachusetts Lowell Shakhashiri of the University of Wis- cants are expected to match the award. Department of Chemistry, Olney Hall consin. Many of us have seen his lec- Eligibility: Applications will be 265 Riverside Street-Room 520 ture demonstrations in the past and, accepted from students at colleges and Lowell, MA 01854-5047 along with all the children in the audi- universities within the Northeastern Phone: (978) 934-3662 ence, have found them to be delightful Section. The undergraduate student Fax: (978) 934-3013 and very informative. The Museum will must be a chemistry, , e-mail: [email protected] devote the entire day to numerous chemical engineering, or molecular Notification: Applicants will be noti- demonstrations and displays that will biology major in good standing with at fied of the results by e-mail on celebrate the union between chemistry least junior status, and must be cur- November 6, 2001. and art. rently engaged in undergraduate The deadline for electronic sub- Tuesday, Nov. 6th , on a more schol- research. mission of abstracts to the American arly note, a half-day symposium on Application: Application forms are Chemical Society in Washington, D.C. “Chemistry and Art” will be held at The available from departmental offices is November 15, 2001. Forsyth Institute from 4 to 8 PM. Sem- inar topics will range from the uncover- ing of art forgeries, the role of chemistry in art conservation, and the chemical analyses of African art. Among the featured speakers will be Prof. Michael Henchman and Dr. Orrie Friedman of Brandeis University, Mr. Michael Douma from Washington D.C., Dr. Janet Schrenk of MIT, Dr. Richard Chemo Dynamics Newman of the Boston Museum of Fine Art, Prof. Margaret Merritt of Wellesley College, Ms. Francesca 1/3 page Ad Appears here Bewer of the Straus Center for Conser- vation at Harvard University, and oth- ers. Audiences will be able to join in Ad # CHEM 681N the discussions during open “Ask the Speakers” periods. Strip Repro supplied The Forsyth Institute, with its world- renowned research program housed in a remarkable building with marvelous architecture and a beautiful collection of Delft tiles, is an ideal location for this symposium. It is located at 140 The Fenway, next to the MFA (parking available in the adjacent parking lot). For more information, see the NESACS website: http://www.nesacs.org

8 The Nucleus October 2001 dent is not interested in science. According to Rep. Boehlert, the ACS/NESACS News administration is very interested in sci- Recent Government Relations Activities ence issues. Immediately following the brief- By Michael J. Hearn cus Peacock from the Office of Man- ing, ACS members visited with mem- On 30th April the Northeastern Section agement and Budget. These policy- bers of Congress to deliver the was very well represented at the Wash- makers discussed the agencies’ budget message that federally funded research ington meeting of the American Chem- priorities and gave an overall picture of is our nation’s foundation for the ical Society Joint Board-Council the administration’s budget. Represen- future. They emphasized that the right Committee on Chemistry and Public tative Ralph Hall (D-TX), top Democ- mix of tax incentives, intellectual prop- Affairs (CCPA), with participation by rat on the Committee on Science, also erty incentives, and federally sup- Drs. Doris Lewis, Tim Rose and provided an overview of important sci- ported research is imperative for Michael Hearn. In several actions the ence issues being discussed in Con- continued science innovation and eco- CCPA broadly supported the goals of gress. nomic growth. ACS members also the ACS on federal funding for The second day of the event began advocated increased funding levels for research and development, the envi- with a breakfast briefing keynoted by the National Science Foundation ronment and science education. Mem- Representative Sherwood Boehlert (R- (NSF), the Department of Energy, the bers of the CCPA were briefed by a NY), Chairman of the House Commit- Department of Defense, and the number of officials from the Adminis- tee on Science. He urged scientists to National Institutes of Health. Most of tration, including the new science and continue pushing for investments in the over 60 congressional offices that technology advisor to Secretary of R&D. Having recently spoken with his were visited responded by expressing State Colin Powell, Dr. Norman congressional colleagues and adminis- support for federal investments in Neureiter, who is himself a Ph.D. tration officials about the budget, Rep. R&D, especially for NSF. Among the . Boehlert was optimistic that more offices visited were those of Senators Over 200 scientists and engineers money would be available for research Kennedy, Schumer, Clinton, Lieber- converged on Capitol Hill on May 1-2 in this year’s budget than initially man, and Dodd and those of Represen- for the sixth annual intersociety Sci- anticipated. He also stated that the sci- tatives Simmons and Gilman. As well ence, Engineering, and Technology ence community should not view the as supporting ACS positions, ACS par- Congressional Visits Day. The purpose administration’s delay in naming a sci- ticipants indicated that the Society can of the day was to show united support ence advisor as a sign that the presi- continued on page 10 for increasing federal funding for R&D. The multi-society event included 38 members of the ACS Board of Directors, the Committee on Chemistry and Public Affairs, and local sections. Drs. Tim Rose and Michael Hearn of the Northeastern Section joined President-Elect Eli Pearce and numerous other ACS mem- Univ. New Hampshire bers from around the country in calling on Representatives and Senators in the United States Congress to voice sup- 1/3 page Ad Appears here port for ACS positions on science edu- cation, the environment, and federal funding for research and development. Ad # UNIV 685N Before meeting with their legisla- tors, participants had been briefed by Joseph Bordogna, Deputy Director of Strip Neg Supplied the National Science Foundation; Daniel Goldin, Administrator of the National Aeronautics and Space Administration; James Decker, Direc- tor of the Department of Energy’s Office of Science; Karen Brown, Act- ing Director of the National Institute of Standards and Technology; and Mar-

The Nucleus October 2001 9 currently 55 chemistry departments. In ACS/NESACS News addition, there are biochemistry Continued from page 9 Meeting departments, food chemistry depart- serve as a valuable resource of infor- ments, etc. mation and interpretation of science Report The total number of chemistry stu- matters for legislators. The true impact Chemical Education at dents (for 1999) was 21,000 in univer- sities, and 4,300 in Fachhochschulen. of these visits will not be known until German Universities the conclusion of the appropriations Chemistry departments are distributed season. ACS members can learn more Summary of the address by Prof. in universities all over Germany, with about this at the ACS website Carsten Bolm, (Institute for Organic fewer being in the former East Ger- (http://congress.nw.dc.us/chemical/) Chemistry, Rhine-Westphalia Technical many. On Monday, 7th May, Drs. Mike University, Aachen) at the May 3, 2001 How do students who want to study Strem and Michael Hearn visited the Symposium, held at Boston University. chemistry decide which university Massachusetts State House to person- General Introduction to attend? ally deliver letters of support from A recent article in the Wall Street Jour- Those who are interested in a research ACS President Attila Pavlath on pro- nal stated: “Once proud German uni- career will choose to go to a university, posals for significant new Common- versities now get low marks”. This talk those who are interested in practical wealth legislation on the environment showed that this is not correct, at least applications will choose a Fach- and public health. Drs. Strem and not as far as professional training in hochschule. In addition, some institu- Hearn were joined by Ray Garant chemistry is concerned. tions have specialized departments (ACS Washington staff) and Matt Students who enter universities in which may be chosen by a minority of Gardner (MIT). The letters were Germany do so after passing the termi- students. addressed to The Hon. Marian Walsh nal examination in high school, the In the U.S., ratings of colleges and (Joint Committee on Taxation) and The Abitur, at age 18 or 19. Some students universities are very important factors Hon. Richard Moore (Joint Committee take a “Fachabitur” in some special in student choice. Even though there on Health Care), Chairs of key com- branch, instead, which allows them to are such ratings (most recently in the mittees for passage of the ACS-sup- enter a “Fachhochschule”. Most stu- Stern, a popular illustrated magazine) ported measures. The new bills have dents with Abitur or Fachabitur will go such ratings do not have much impact been introduced by Representative on to university-level studies (68% in on students’ choices in Germany. Douglas Petersen. ACS members are 1999, but down from 82% in 1990, In fact, most students choose a invited to visit the ACS website which has caused concern). Many with university close to home, or mostly in (http://congress.nw.dc.us/cgibin/statein Abitur will attend a University or a the same state. Another factor, as to the dex.pl?state=ma&dir=chemical) to Technical University, resulting in a subject chosen, is the expense of study: learn more about these measures and Diplom degree (4-5 years) and proba- Although there is no tuition at German how they can voice their opinions bly Ph.D. (called Dr. rer. nat.), those universities, and all universities are with Fachabitur will attend a Fach- under state control and financed by the hochschule, resulting in Dipl. Ing. state, living expenses are considerable, (Diplom in Engineering) degree. so that studying chemistry to the A few institutions now give Bach- Diplom will require expenditures of elors and Masters degrees. about $50,000. In Germany currently 28% of Another difference from study in pupils born in one year will go on to a the U.S.: Students tend to stay at the university or technical university. In same institution, even after the 4-5 some countries about 40% go to uni- year Diplom degree they are likely to versities, but in Germany there are stay at the same university for pursuing other pathways of specialization out- the doctor’s degree. Only about 16% side of the usual university system. move to another university for their Currently there are 308,000 begin- doctoral work after completing the ning students in German universities, Diplom degree. but the prediction for 2015 is only Whereas American chemistry stu- 274,000, which is a cause of concern. dents tend to select graduate schools Universities and Technical Uni- because of the reputation of their versities focus on research; the Fach- chemistry departments, in Germany hochschulen focus on applied subjects the primary selection would be that of leading to the Dipl.Ing. degree. the professor of the student’s choice. In German universities there are continued on page 11

10 The Nucleus October 2001 Compared to the U.S., there are very “good”. By the time they have gone on carried out may be influenced by the few post-doctorals in Germany, and to the Ph.D., 73% will receive “very mentor’s interests. Also, the choice of those often come from other European good” marks, and 15% “distinction”, topic will be determined by the avail- countries or Asia. which is above “very good”. ability of rather scarce research funds. After habilitation, the title will be that How is the chemistry curriculum Future trends of “Privatdozent”, with unsure monies organized? Was covered more in detail by Dr. available either for research or mainte- In the traditional course of study, enter- Mitchell’s talk. The meeting in nance. The system is very brutal: If ing students will have 4 semesters of Bologna may result in internationaliz- successful and the Privatdozent is basic study, including much laboratory ing chemistry study to a greater extent, invited to a position at a university, the work, followed by a preliminary exam- with the programs in the European aspirant is almost assured to obtain a ination (Vordiplom), which must be countries becoming more alike. Rec- position for life, as Professor, and passed to be allowed to go on, fol- ommendations may result in educating finally to retirement. If the Privat- lowed by four semesters of advanced students more broadly, i.e. getting dozent does not succeed in obtaining a study, again including laboratory work, away from the high degree of special- position, it is total failure. There are no followed by 1-2 semesters of research ization that currently exists. lesser schools where there might be for a diplom thesis and a series of The first degree may become a positions, which is different than the diplom examinations. After this the Bachelor’s degree, which comes earlier situation in the U.S. where those who student receives a Diplom degree than the current Diplom degree. do not succeed in obtaining faculty (Dipl.Chem. or Dipl.Ing.). The total In addition, there may be a divi- positions at the major research univer- time for this will be about 5 years. sion in paths to research and to applied sities may be able to join the faculties Most of the students will go on for degrees or joint degrees, such as chem- at non-research universities or col- doctoral study, which is entirely istry and economics, for example. leges. research, requiring approximately 7 This combination already exists at Under a new system being dis- semesters, and resulting in the Dr. the University Ulm where a Diplom cussed, junior professorships have rer.nat. (Ph.D.). About 90% of those degree is given in chemistry and eco- been considered, but the idea is not receiving the Diplom degree go on for nomics (“Wirtschaftschemie”) after 8 liked by most chemistry academics. doctoral study. semesters. A similar combination To give an example of the German As an example, at the Aachen degree is given at the University university system, Dr. Bolm gave his Technical University, in the first year Clausthal after 6 semesters of study, own curriculum vitae: He started out at students each week will take four followed by a Master’s degree. Many Braunschweig University, was one of hours of Physics lectures plus two other combinations may be given. the few who changed to another uni- hours lab, three hours Inorganic Chem- Since all universities operate versity (Madison, WI), then received istry lectures plus 12 hours lab and under government control and with his Diplom degree at Braunschweig. three hours of mathematics. In follow- government monies, when the number He was among the 16% who go to ing years, the courses will be in analyt- of students in a department becomes another university for the doctor’s ical, organic, , etc. too small, the government may actu- degree, in his case at Marburg. After By semester 8 there will be few lec- ally close departments. Currently two post-doctoral work in the U.S. (MIT) tures, but mostly lab. work. departments are in danger of losing he habilitated in Basel, Switzerland Obviously, German chemistry stu- chemistry departments for this reason. and became Professor of Chemistry in Marburg. Later he received a call to dents spend much more time in the How do you become a Professor in laboratory, and fewer hours in lectures Aachen for a full professorship, his Germany? than in the US. In addition, it is to be present position. noted that German students will take After receiving the doctor’s degree, no courses other than chemistry or most of those aspiring to an academic related subjects, i.e. no “distribution career will do a post-doctorate, fre- courses”. quently in another country, including After the Diplom degree, doctoral many in the U.S. Following this, the Have you looked study is primarily specialized research aspirant will select a strong mentor, i.e. work. a professor in the field of interest, with at the NESACS whom the aspirant will carry out inde- Grading: pendent research for another 3-5 years, website? German grading is 1-6, with 1 being resulting in another thesis, and if suc- best (very good), 2 good, etc. cessfully completed and defended, An example of grades given: resulting in “Habilitation”, the permis- About 26% of diplom students will sion to teach at the university level. If WWW.NESACS.org receive “very good”, about 50% the mentor is very strong, the research

The Nucleus October 2001 11 vised by Samuel M. McElvain, he worked on barbiturates and synthe- New England Chemists sized compounds to be tested as local ACS “Moving Forces” IV. Arthur C. Cope (1909-1966) anesthetics, one of which was eventu- By George B. Kauffman Chemical and Engineering News as ally developed for clinical use. Cope remained interested in medicinal one of C&EN’s Top 75 Distinguished The series commemorates the 125th chemistry for many years. Contributors to the Chemical Enter- anniversary of the founding of the ACS After a postdoctoral year as a prise; and at the 217th National Meet- in 1876, to be celebrated this year. National Research Council fellow at ing of the ACS in Anaheim, California, Reprinted by permission from “Chemi- Harvard University with Elmer P. 21-25 March 1999, the Division of Kohler, in 1934 Cope became an asso- cal Heritage” 19:1 (Spring 2001) 47- Organic Chemistry held a two-day 48. ciate at Bryn Mawr College, which had symposium to mark the Cope Award’s a long tradition of teaching and Arthur C. Cope was truly a moving 25th anniversary and to commemorate research in organic chemistry. He force in the ACS. Renowned for his Cope’s legacy. Fourteen of the 19 liv- became assistant professor in 1935 and pioneering scientific contributions, he ing Cope medalists, a virtual who’s associate professor in 1938. During his is also revered for his endowment of who of international organic chemistry, research on the synthesis of barbitu- the Arthur C. Cope Award. Cope be- including two Nobel laureates, spoke rates he discovered a new rearrange- queathed half of his estate to the ACS at the symposium. ment, similar to the Claisen to advance research and education in Arthur Clay Cope was born on 27 rearrangement, that involved the shift organic chemistry. This endowment June 1909 in Dunreith, Illinois, the son of allyl groups in a three-carbon sys- funds the Cope Award, which has sup- of Everett C. Cope and Jennie Cope tem. The method, known as the Cope ported significant research by some of (née Compton), grain-storage opera- rearrangement, was useful for synthe- the most eminent organic chemists of tors. He earned his A.B. degree from sizing complex natural products. It our time, and its companion the Cope Butler University in Indianapolis in earned him the ACS Award in Pure Scholar Award, which has helped train 1929, then received his Ph.D. degree in Chemistry in 1944. and nurture young scientists. In 1998 1932 from the University of Wiscon- In 1941 Cope was awarded a he was nominated by readers of sin. For his doctoral research, super- Guggenheim fellowship for “Studies of

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12 The Nucleus October 2001 the Phenomenon of Tautomerism,” and research with valuable public service; aid of $150,000; and Cope’s endow- he became associate professor at Co- few ACS members have devoted more ment has grown so much that in 1984 lumbia University. From 1942 to 1944, time to the society than Cope. He the ACS used the income to establish while on leave from Columbia, he served on its board of directors (1951- the Arthur C. Cope Scholar Award, worked on chemical-warfare agents 66), was chairman of the board’s publi- currently $5,000 and a $40,000 unre- and antimalarial drugs as technical cations committee (1952), and was stricted research grant. Each year up to aide and section chief in the Division twice elected chairman of the board ten scholars are named. of Chemistry of the National Defense (1959—60; 1962-66). He was also Thus, long after his premature Research Committee. In 1945 he was elected chairman of the Division of Or- death, Arthur C. Cope continues to appointed professor of chemistry and ganic Chemistry (1947), chairman of contribute to the science and profes- head of the Division of Organic Chem- the Northeastern Section (1955), and sion that he loved so well. istry at the Massachusetts Institute of president of the society (1961). He For further Reading Technology. Six months later he served on the Committee on Profes- became head of the chemistry depart- sional Training for nine years and on Roger Adams, “Arthur Clay Cope 1909- ment, a position he held until 1965, the editorial boards of the annual pub- 1966.” Proceedings of the Robert A. when he was appointed the first lication Organic Syntheses and serial Welch Foundation, Conference on Camille Dreyfus Professor in Chem- publication Organic Reactions. He also Chemical Research 10 (1967), 1-3 istry in recognition of his outstanding served as chairman of the Chemical “Arthur C. Cope, ACS President in contributions to the department. He Section of the National Acadeny of 1961.” Chemical and Engineering News hired a number of brilliant chemists, Sciences, to which he was elected in (C&EN) 39:1 (2 Jan. 1961), 72, 74. including the organic chemists John D. 1947. “Arthur Cope Dead at 56.” C&EN 42:24 Roberts, John C. Sheehan, and Gardner Cope’s awards included the ACS (13 June 1966), 25-27 C. Swain, and developed one of the Award in Pure Chemistry (1944), “Contributions to the Chemical Enter- nation’s most outstanding chemical Columbia University’s Charles Freder- prise: C&EN’s Top 75.” C&EN 76:2 (12 research departments. ick Chandler Medal (1958) for his Jan. 1998), 171-185 Cope’s research involved medici- work on medium-sized ring com- nal compounds, reactions of cyclic car- pounds and his recognition of transan- “Cope Awarded Nichols Medal.” C&EN bon compounds, reactions across rings, nular reactions, the ACS New York 42:11 (16 March 1964), 78. carbonyl reactions, amine oxide Section’s William H. Nichols Medal Lester Kieft. “Arthur Clay Cope 1909- rearrangements, optical activity in (1964), and the ACS Roger Adams 1966.” In American Chemists and cyclic olefins, structures of antibiotics, Award in Organic Chemistry (1965). Chemical Engineers, ed. Wyndham D. and reactions of , , In 1930 Cope married Bernice Miles (Washington, D.C.: American and cobalt salts with unsaturated Mead Abbott. The couple had no chil- Chemical Society, 1976),93-94. hydrocarbons to form metal-carbon dren and were divorced in 1963, the John D. Roberts; John C. Sheehan. bonds. Besides the Cope rearrange- year in which he married Harriet Arthur Clay Cope, 1909-1966.”Bio- ment, his resolution of trans- Packard and acquired a stepson, Gre- graphical Memoirs of the National cyclooctene, a triumph of experimental gory Cope. He was not a demon- Academy of Science 60 (1991), 16-30. skill, provided further support for con- strative person but knew how to use Herman Skolnik; Kenneth M. Reese, cepts of three-dimensional arrange- power effectively. He died of a sudden editors. A Century of Chemistry: The ments of organic compounds. He heart attack while dining with ACS Role of Chemists and the American published more than 200 papers and colleagues in Washington, D.C., where Chemical Society. Washington, D.C.: was a consultant for Sharpe and he had gone to attend an ACS board of ACS, 1976. Dohme, DuPont, and Merck. His col- directors meeting. Dean Stanley Tarbell. “Arthur Clay laboration with Merck led to four new Cope’s estate, resulting from Cope, 1909-1966.” in American compounds, including the sedative royalties, patents, and successful National Biography, ed. John A. Gar- Delvinal Sodium and the muscle relax- instruments, was considerable, and the raty and Mark C. Carnes (New York: ant Flexeril (cyclobenzaprine hydro- Cope Award that the ACS funded with Oxford University Press, 1999), vol. 5, chloride). Many of his numerous its half was first given in 1973 to 471-472. students have had outstanding research Robert B. Woodward and Roald Hoff- careers in their own right. mann. The award, the most lucrative Dean Stanley Tarbell; Ann Tracy Tar- Cope was extremely active in his administered by the ACS, recognizes bell. Essays on the History of Organic work for the national community of “outstanding achievement in the field Chemistry in the United States, 1875- chemists; much of his work was, of organic chemistry the significance 1955. Nashville, Tenn.: Folio Press, associated with another ACS “moving of which has become apparent within 1986. force,” Roger Adams (see Chemical the [preceding] five years.” The award Pamela S. Zurer. “Symposium Cele- Heritage, Summer 2000, pp. 47-48). currently includes a gold medal, brates 25 Years of Cope Awards.” He combined significant scientific $25,000, and an unrestricted grant-in- C&EN 77:14 (5 April 1999), 33-37.

The Nucleus October 2001 13 ing techniques, available libraries on the Internet and computer analysis, he Book Review moved ahead the effort to map the Bold Science: Seven Scientists Who Are Changing Our World, human genome at a dramatic pace. by Ted Anton (W.H. Freeman and Company, 2000)193 pp., ISBN: 0716735121; In the second chapter, we are $24.95 (hardcover) drawn into the whirling mind of Susan Greenfield as she began her Reviewed by Maryann C. Kenney, Evergreen Solar, 211 Second Avenue, studies as a philosophy major, moving Waltham, MA 02451 by chance and inevitability into the field of neuroscience. Here is a scien- What is Bold Science? It is the quest and the larger significance of the work tist relentlessly curious, questioning for answers to the far-reaching ques- accomplished. This book is very read- the workings of the mind, and playing tions of our times; questions that able, even without extensive knowl- catch-up in a field she had just joined. range across conventional disciplines edge of these fields. Several chapters Susan Greenfield is also a good exam- and challenge our knowledge of the are extremely evocative portrayals of ple of Anton’s point, that modern bold world. While we could all easily the individual behind the research; scientists are often adept at using the choose great names from the past who their drive to question, to educate media to communicate their bold followed this bold approach, picking themselves and to form new answers. ideas and educate the non-scientific names from today’s diverse roster of According to Anton, “By combining public. She is well known for her scientific endeavor is more complex. the cheap tools of personal computers, BBC series and popular book on the Ted Anton has selected seven scien- remote sensors, the Internet, and basic brain. tists who have made dramatic contri- artificial intelligence systems, they The third chapter, on Geoffrey butions to important, timely fields that began to open an exhilarating and Marcy in his long and lonely quest for have significant implications for the frightening era in genetics, ecosys- extra-solar system planets is the most progress of science. tems, cosmology, and neuroscience”. compelling in its tale of many years In each chapter Anton traces the The first chapter, on Craig Venter, spent in the trenches of scientific scientist’s early path, the varied embodies much of this approach. endeavor. We are shown a young approaches and turns upon this path, Combining automated DNA sequenc- astronomer who, early in his career, had declared himself a “fully fledged failure”. From these feelings he reached out to a scientific quest he truly loved, something he could pur- sue regardless of career success or failure. There followed years of hard work, teaching full days, pursuing astronomy nights. He worked on the proverbial shoestring, cajoling help, Eastern Scientific embodying teamwork, and faced with setbacks. We are uplifted in his even- 1/2 page Ad Appears here tual triumph. In the remaining chapters, Polly Matzinger conceived of an entirely Ad # EAST 584N new model for immunology and the fundamental question of how the body tells self from non-self. Her path to a Strip Repro supplied career in science is a fascinating tale of many early turns and broad ranging interests in life. Her approach was interdisciplinary, and at times combat- ive, but dramatic in its result. Saul Perlmutter’s quest is to find and meas- ure supernova explosions as a way to probe the age and fate of the universe, continued on page 15

14 The Nucleus October 2001 Increasing Size of Society Commit- Book Review tees, B.III, Sec. 3,e(7), which was pre- Continued from page 14 Council sented for Urgent Action. To do this successfully, he used the A corresponding increase of Internet, and his personal enthusiasm, Meeting Standing Committees and Elected to coordinate the searches of observa- Committees had been voted at the San tories around the world. There were Diego meeting. After receiving reports Report from major committees who were times of solid collaboration, but also Chicago, IL, August 29, 2001 events of professional jealousy. opposed to Urgent Action (i.e. imme- Gretchen Daily combined the disci- Our Section was fully represented by diate action without the benefit of plines of economics, ecology, biology 10 Councilors and two Alternate prior discussion of the merits of the and chemistry to ask “big questions Councilors. petition in committees), it was MOVED that the vote on Urgent about the complex interactions of About the ACS meeting itself, by Action be postponed indefinitely. This nature and our role in it.” She Tuesday a.m. the total registration was was a maneuver to allow the petition launched her path through the 15,290. Combined with the good to go back to the petitioners for suit- unlikely coupling of German litera- attendance at the San Diego Meeting, able modification since there was an ture and Geology. Carl Woese did this constituted the largest yearly inconsistency between the proposed nothing less than find a whole new attendance at national meetings in Society Committee size and other pro- kingdom of life with startling implica- ACS history. visions in the bylaws, which require at tions for where we fit in the grand At the National Employment least 2/3 of the members being coun- schema of earth. Clearing House, 1392 positions were cilors Ð (the proposed maximum size In the final chapter, Anton tries to listed by 169 employers. There were [20] is not divisible by three). Defeat- weave together common threads from slightly over 1000 job seekers. ing Urgent Action itself would have all of the scientists. For many, the The following items were pre- had the effect of assigning the petition presence of the Internet has brought sented for approval by Council: immediately to a committee without it the international research community (All NESACS Representative being able to change the numbers closer, and has allowed faster collabo- voted in favor of the motions pre- beyond those in the petition. The ration across fields and geographic sented and passed by the Council). boundaries, accelerating the pace of Continued on page 16 progress. It has also brought a height- ened sense of competition in the drive to be first, and the desire to be acknowledged. At the same time, there is a refreshing sense of team- work among many of these scientists, and a willingness to discuss and explore in the classic traditions of aca- demia. We see repeatedly the power of the academic soirée, and the exchange of ideas over good wine and food. Undeniably, computer technol- ogy, new sensors, and more process- ing power, have made studies possible that would have been unheard of ten years ago. Also, in many of these tales, the scientist professes a pro- found doubt or insecurity in his or her own abilities at some point in their career. How reassuringly human this is. Perhaps each is most bold in their very unique and personal quest for science.

The Nucleus October 2001 15 Expositions reported that at this meet- cussion of new procedures for select- Council Meeting ing 6089 papers were presented in 66 ing recipients of Grassroots Achieve- Continued from page 15 sessions, including the several poster ment Awards, and new aspects of the Council VOTED in favor of indefinite sessions. At the Exposition, 328 com- Legislative Action Network. postponement with only a few “nay” panies had displays in more than 500 Doris Lewis attended the meeting votes. booths. of the same parent committee. She All meeting rooms had been pro- also mounted the material for the Meeting Registration Categories vided with computer-linked projectors poster “100 Years Northeastern Sec- B. VI, Sec. 4,b and Section 4,e. for Powerpoint and similar presenta- tion”, which featured the display of The effect of this petition is primarily tions. It was hoped to eliminate 35mm pictures of the 10 Nobel Laureates of to eliminate the distinction between slide projectors in the future, however the Section (an enlargement of the domestic and foreign non-members overhead projectors are to be retained. center-spread in the February 1998 registrants as far as registration cate- In the future, meeting programs 100th Anniversary Issue of The gories and meeting fees are concerned. will be bound separately, but mailed NUCLEUS.). This material was pre- Also, a new registration category for together with C&EN. Of course, sepa- sented at poster sessions of the Divi- Student Affiliates is proposed. The net rate programs will be available at the sion of Industrial and Engineering effect of the change would be to meetings themselves, as before. Chemistry and the Division of Chemi- increase the registration fees for non- For 2002, National Meeting pre- cal Education. member chemists or visitors from registration fees for members will be Arno Heyn visited the meetings of abroad to be the same as those from $265. the Constitution and Bylaws Commit- the U.S. and Canada. There were some floor comments tee and participated in the discussion The amendment was VOTED on the large distance between hotels of draft petitions which had been pre- with only a few nay votes. and the Chicago Convention Center sented to the committee. Clarification of Requirements for which, even with the bus shuttles pro- Arlene W. Light attended meet- Membership, B. I, Sec. 3,a vided, presented schedule conflicts. In ings of the Committee on Economic A separate category for those with an answer, the N&E Chair pointed out and Professional Affairs and together associate degree or equivalent and five that because of our meeting size, only with Truman Light, worked in the years experience in chemical science 6 cities in the US can accommodate Career Services department (Natl. is to be provided by this petition. Cur- meetings of this size, and that the Employment Clearing House) Sunday rently, Chemical Technologists who trend is to build convention centers through Wednesday. apply for membership can be accepted quite far from the downtown hotel At the ChemLuminary Awards at under B.I, Sec.5 (Less formal training sites, something the ACS cannot con- the National ACS meeting in Chicago, than above, but with significant trol. Amy Tapper, chair of the YCC, achievement in chemical science), but Project SEED reported that for accepted the Outstanding Local Sec- each case has to be considered individ- 2001 there were 293 first-year and 49 tion Younger Chemists Committee ually. With the new provision, admis- second-year SEED students. From Award for the Northeastern Section sion is simplified for this category of these, 33 obtained college scholar- YCC. This award was given in recog- members. The Petition was VOTED ships. For 1999-2000, 66% of the nition of the various activities of unanimously. SEED participants chose to become the YCC in 2000. This is the second Among the Committee reports, chemistry majors in college. year in a row that the Northeastern the Committee on Budget and Finance The following NESACS Coun- Section YCC has won an award. reported that largely because of the cilors reported on committee activi- http://people.bu.edu/nsycc. decrease in interest rates, the income ties: of investments of the ACS was pro- Tom Gilbert, as Chair of the N&E jected to be lower than budgeted by Task Force on Election Procedures, about 8 M$ for 2001. However, better met with the Constitution and Bylaws than expected revenues from the Committee to discuss bylaws changes Chemical Abstracts Services partially which may become necessary if elec- made up for this deficit. tronic voting is introduced. A draft The Committee of Divisional petition may be presented at the fall Activities MOVED that a Probation- meeting. ary Division of Laboratory Automa- Michael Hearn, as Subcommittee tion be established, which was Chair of the Advocacy Subcommittee L. to r.: M. Strem, Amy Tapper VOTED with only one nay vote. of the Committee on Chemistry and (YCC), M.Z. Hoffman at the The Committee on Meetings and Public Affairs participated in the dis- Chem.Mixer/poster session.

16 The Nucleus October 2001 most of the offices of NEACT as well Puzzle as serving as an advisor to the summer Historical conference program and to other activities of the Association. A com- Column Notes plete account of his work has been Answer to the September puzzle Continuation of biographies of published by NEACT and is available If the radius of the small circles is 1, the recently deceased chemists and on request. For all these services he radius of the large circle is 3. The areas are chemical engineers received several awards of NEACT. proportional to (radius)2, therefore 1:9 . In addition he received the Elizabeth There are seven small circles contained in Louis W. Mead, 80, died on Decem- Thompson Award for excellence in the large circle, therefore the shaded area is ber 7, 2000 at his home in Lexington, teaching made by the American Acad- equal to twice the area of one of the small Mass. after a long illness. He was a emy of Arts and Science (1956), the circles. native of St. Louis and a chemical Howard Wagner Award for outstand- New Puzzle engineering graduate of Cornell Uni- ing service to science education in New Hampshire (1991) and was The Mensa Mind Challenge: Part I versity. As a member of the 4th Engi- neers Special Brigade during World elected to the Aula Laudis Society of This puzzle appeared in American Way, the War II he participated in amphibious the Northeastern Section, ACS American Airlines in-flight magazine. landings in the Pacific theater. After (1990). Reprinted with permission of American the war he was employed in research The last named honor was for Mensa Limited, 1229 Corporate Drive Marco’s service as a teacher, but he West, Arlington, TX 76006; at Oak Ridge, Tenn. and at M.I.T..He served his professional societies as www.us.mensa.org. founded several small firms that Source: Abbie F. Salny, Ed. D., Mensa’s developed radiopharmaceutical diag- well. In addition to his services to supervisory psychologist nostic tests, some of which are cur- NEACT he was also an active mem- ber of the Northeastern Section, ACS. 1. Fill in each of the blanks below with a rently used by hospitals. He was the In the 1950’s when I was an officer of word that means the same as the words founder of the Mount Agamenticus on either side. ski area in southern Maine. the Section I noted that Marco and his wife were frequently seen at Section (transparent) ______(evident) James H.Parliman died on June 15, meetings despite the tedious drive to (type of precipitation) ______1999 after a short illness. He was a (greet) Cambridge. I accepted his offer to 1943 graduate of the Worcester Poly- serve on Section committees. At a 2. The equation 143 + 586 = 729 uses technic Institute and was a longtime time when active Section members the digits from 1 to 9 only once each. member of ACS. He lived in Keene, There are many combinations of those from secondary schools were few N.H. and was survived by his wife. Marco was outstanding. Had Aula numbers that will produce the same We regret that we have been unable to result. Can you find three of them? Laudis then been in existence he acquire additional material on his would have been among its first mem- 3. The names of three U.S. cities have career from his estate. been interlaced below. Can you find bers. them? (Hint: they’re in the eastern half Marco H. Scheer, 81, died on May Sukant K.Tripathy, 48, professor of of the U.S.) 11, 2000.He was a native of Manches- chemistry at the University of Massa- BTIORTSOHTYAOCNA ter, N.H. and had lived in Nashua chusetts, Lowell, and director of its 4. Fill in the following word square using since 1947. He received the cum laude Center for Advanced Materials, one letter S, two each of the letters T, U B.S. in biochemistry from Tufts Col- drowned on December 12, 2000 while and E, four letter As and five letter Rs, lege in 1940 and then began his life- swimming in Hawaii where he was so that each word can be read both long teaching career at Nashua High attending the Poly Millenial Confer- across and down. School. He was a General Electric ence. A full biography of Sukant has ST A R Science fellow at Union College in been published in C&EN, Jan. 22, 1946 and in later years pursued gradu- 2001, p.116. T ate work at Boston University, Lowell A Technological Institute, and Rivier College. Beginning in 1950 Marco R became a well-known member of the New England Association of Chem- 5. What is the number that is 10 more than istry Teachers (NEACT) and almost 1/4 of 1/10 of 1/5 of 800? until the time of his death occupied (Answers next month.) The Nucleus October 2001 17 First Annual Nucleus Buyers Guide Your Buyers Guide Listing is free! If you are not listed in problem, need equipment, restock inventory, or require con- this year’s Guide, please contact Vince Gale at: Phone 781- sultant services. they will keep this reference until the next 837-0424, Fax 781-837-8792, e-mail: [email protected] one is published in 2002 The purpose of the Guide is to provide a ready refer- This directory will be given to our 7,500 members for ence of companies providing products and services that are their use. This issue has excellent advertising value because of interest to our American Chemical Society members. Our it is kept and referenced for the full year members will use this guide as a way of finding vendors If you wish to be in next year’s Guide, please contact Vince who can service their needs when they are trying to solve a Gale as noted above. 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The Nucleus October 2001 19 COMPANY DIRECTORY

(631)231-3334 (757)393-1584 (516)939-0555 www.usa-idi.com controlotron.com (757)393-3708 www.hellmausa.com [email protected] [email protected] www.firsttenangstroms.com [email protected] 121, 172A 111 [email protected] 133,168,171,176 ISS D.C. Scientific LLC 10 Hiden Analytical 1602 Newton Drive Dittmar Wulff, Owner Fluid Metering, Inc. Terry Whitmore Champaign IL 61822 P.O. Box 140 5 Aerial Way-Suite 500 75 Hancock Rd. Suite H (217)359-8681 Kelton PA 19346 Syosset NY 11791 Peterborough NH 03458-1100 (217)359-7879 (877)869-3232 (800)223-3388 (603)924-5008 www.iss.com (610)869-8594 (516)624-8261 (603)924-5009 [email protected] www.dcsci.com www.fmlpump.com www.hidenanalytical.com 167 infodcsci.com [email protected] [email protected] Jordi Associates 41,42,44,47 126 5,12D,25,137,138,172 Pam Jordi, Vice President Dannier Chemical, Inc. Frinton Laboratories, Inc. HT Laboratories, Inc. 4 Mill St. Howard M. Paul, Sales Manager Inglessis Dr. George Albert Chong, COO Bellingham MA 02019 2472 Chambers Rd. Suite. 230 Marketing Manager 9823 Pacific Heights Blvd,SteF (508)966-1301 Tustin CA 92780 P.O. Box 2428 San Diego CA 92121 (508)966-4063 (714)832-6882 Vineland NJ 08362 (858)677-9432 www.jordiassoc.com (714)832-6929 (856)722-7037 (858)677-0240 [email protected] www.dannier.com (856)439-1977 www.HT-LABS.COM 12C,44 [email protected] www.frinton.com [email protected] Kewaunee Scientific 28 [email protected] 12D,19 Equipment Desert Analytics 146 Huffman Laboratories, Inc. Cynthia J. Freeze Dr. R.C. Johnson, President Front Run OrganX, Inc. Ron Keil, Laboratory Director Marketing Manager P.O.Box 41838 Mallory F. Loewe, Ph.D. 4630 Indiana St. P.O. Box 1842 Tucson AZ 85717 President Golden CO 80403-1849 Statesville NC 28687-1842 (520)623-3381 17 Hayward St (303)278-4455 (704)873-7202 (520)623-9218 Ipswich MA 01938 (303)278-7012 (800)932-3296 www.desertanalytics.com (978)356-7133 www.huffmanlabs.com www.kewaunee.com [email protected] (978)356-7449 [email protected] [email protected] 145 [email protected] 145 92 Digilab 28,35A,64,65,77,146 Hydro Slip Technologies, Kimble/Kontes Patty Lee Goldstein Associates Inc. David Fenili, Marketing Communications Mgr. Dr. Al Goldstein, President Dr. Al Goldstein, President Advertising Manager 68 Mazzeo Drive P.O. Box 88 P.O. Box 88 1022 Spruce Street P.O.Box1502 Randolph MA 02368 Adelphia NJ 07710 Adelphia NJ 07710 Vineland NJ 08360 (800)225-1248 (732)780-7171 (732)780-7171 (856)692-8500 (781)986-5013 (732)462-3644 (732)462-3644 (856)692-8134 www.bio-rad.com www.monmouth.com/~goldstein [email protected] www.kimble-kontes.com [email protected] [email protected] 77 [email protected] 169 65,68A,74,75,76,77 ICON (Isotope) Services Inc. 116 Eastern Chemical Div Unt GOW-MAC Instruments Co. John Kilby, Marketing Manager Kinetic Systems Guard Gail Johnson, Marcom Manager 19 Ox Bow Lane John Bacevil, Pru Gallo, Sales 277 Broadhead Rd. Summit NJ 07901 Marketing Manager P.O. Box 18050 Bethlehem PA 18017 (908)273-0440 20 Arboretum Road Hauppauge NY 11788 (610)954-9000 (908)273-0449 Boston MA 02131- (631)273-0900 (610)954-0599 www.iconisotopes.com (617)522-8700 (631)273-0858 www.gow-mac.com [email protected] (617)522-6323 [email protected] [email protected] 35 www.kineticsystems.com 37 5,43,84A,85,86,87A IKA Works [email protected] Excel for Heidolph Instruments David Fumbro, Marketing 138A Scientists&Engineers Bill Conners, Sales Manager Manager Lab Safety Supply Co. Joseph Billo PhD 2615 River Road, Unit 4 2635 North Chase Pkwy., S.E. Cindy Joyce, Copywriter Prof. Dept. of Chem Boston Col Cinnaminson NJ 08077 Wilmington DE 28405 P.O. Box 1368 13 Shattuck Street (888)522-0966 (800)733-3037 Janesville WI 53547-1368 Natick MA 01760 (888)622-4644 (910)452-7693 (608)754-2345 (617)552-3619 www.heidolph.com www.ika.net (608)757-4645 (617)552-2705 [email protected] [email protected] www.labsafety.com [email protected] 109 98,104,114 [email protected] 179B Hellma Cells Instrument Distributors Int’l 156 First Ten Angstroms Daniel Fields, Director of Frank Carpenter, President Lancaster Laboratories Inc. Vernon Eberwine Marketing 7881-H Beechcraft Drive Anne Osborn Marketing Manager 80 Skyline Drive Gaitherburg MD 20879-1507 Business Development 465 Dinwiddle St. Plainview NY 11803 (301)977-0900 2425 New Holland Pike Portsmouth VA23704 (516)935-0007 (301)208-0698 Lancaster PA 17601

20 The Nucleus October 2001 COMPANY DIRECTORY

(717)656-2301 Mettler-Toledo, Inc. 24 Director of Marketing (717)656-0450 1900 Polaris Pkwy Nuclear Associates 1009 Lenox Drive, Suite 104 www.lancasterlabs.com Columbus OH 43240 Stephanie Felner Lawrenceville NJ 08640 [email protected] (800)574-8147 Marketing Manager (609)896-0310 90 (614)438-4871 100 Voice Rd. (609)896-0365 Lancaster Synthesis www.mt.com/na Carle Pl. NY 11514-1593 www.pti-nj.com Pamela Hondros [email protected] (516)741-6360 [email protected] Regional Sales Manager 3,5,7,9,11A,12B,25,99,144 (516)741-5414 167 P.O. 1000 Micron Inc. www.nucl.com Poly(Chem-Tech) Windham NH 03087-9977 James Ficca, President [email protected] Daniel Kruh,Ph.D., President (888)937-5035 3815 Lancaster Pike 152 8 Braddock (603)472-3801 Wilmington DE 19805 Numare Spectralab Inc. East Brunswick NJ 08816 www.lancastersynthesis.com (302)998-1184 Lawrence Byrnes (732)238-3182 [email protected] (302)998-1836 President & Lab Manager (732)238-3182 25A,25B,26,27,28,30,33,35A, www.micronanalytical.com “POB #96, 10 Summit Ave, [email protected] 35B,37 micronanalytical@compuserve. Unit#6” 80A Lehigh Univ Distance Educa com Berkeley Heights NJ 07922- Pressure Products Industries 23,25,65A,69,80B,88,89 Ofc 0096 Michael Walsh, Sales Manager Peg Kercsmar Molecular Knowledge (908)665-0066 900 Louis Drive Manager Distance Education Systems (908)464-4192 Warminister PA 18974 205 Johnson Hall, 36 Univ Dr. Dr. Kevin Joback www.eclipse.net/~numare/ (215)675-1600 Bethlehem PA 18015 P.O. Box 10755 [email protected] (215)443-8341 (610)758-5794 Bedford NH 03110-0755 12H,72 www.gotoppi.com (610)758-6269 (603)472-5315 Oneida Research Services, [email protected] (603)472-5359 www.distance.lehigh.edu Inc. 127 [email protected] www.molknow.com Princeton-Chromatography, 179B [email protected] Deborah A. Delluomo 56 Customer Service Rep. Inc. Libra Technologies, Inc. 1 Halsey Rd. Walton Caldwell Dr. Mike Blumenthal, President Nanmac Corporation Whitesboro NY 13492 Marketing Manager 101 Liberty Street Doug Claffey, Marketing Dept (315)736-5480 1206 Cranbury-South River Rd. Metuchen NJ 08840-1215 9-11 Mayhew Street (315)736-9321 Cranbury NJ 08512 (732)321-5200 Framingham MA 01702 www.ors-labs.com (609)860-1803 (732)321-5203 (508)872-4811 [email protected] (609)860-1805 www.libratechnologies.com (508)879-5450 65A [email protected] mmbphd@libratechnologies. www.nanmac.com 44 com [email protected] Oxford Instruments 65A 87 130A Baker Avenue Ext. Q-Glass Co Inc. Concord MA 01742 Dan Dotterweich, Vice President Matech Associates National Institute Stds & (978)369-9933 624 Rt 202 Dr. B. Chowdhury, Principal Tech (978)369-8287 Towaco NJ 07082 150 East Grove Street Diane Decker www.oxford-instruments.com (973)335-5191 Scranton PA 18510 Standard Reference Data [email protected] (973)335-2057 (570)344-4067 100 Bureau Dr. Stop 2310 178 www.qglass.com (570)689-4752 Gaithersburg MD 20899-2310 [email protected] (301)975-3774 PACS Courses and www.matechlabs.bigstep.com 116 [email protected] (301)926-0416 Conferences 25 www.nist.gov/srd Barbara Sherman, President Quartz Plus Inc. McPherson, Inc. [email protected] 409 Meade Drive Joseph Thomas, Vice President 27 Westview Road Erik Schoeffel, 21 Coraopolis PA 15108 Brookline NH 03033 Marketing Manager NMR Analysis & Consulting (724)457-6576 (603)673-5690 7A Stuart Road Gary Juneau, President (724)457-1214 Chelmsford MA 01824 2121 South Imboden Court www.members.aol.com/hnpacs/ (603)673-5766 (978)256-4512 Decatur IL 62521 pacs.htm www.quartzplus.com (978)250-8625 (217)423-2517 [email protected] [email protected] www.mcphersoninc.com (217)423-2521 179B 116 [email protected] www.nmra-c.com Patterson-Kelley Remspec Corporation 167 [email protected] Mark Zagnojny, Mary Thomson Mettler-Toledo Bohdan, Inc. 72 Marketing Manager Director of Marketing Horst Bodenmann, Northern Analytical 100 Burson St. 512 Leadmine Road V.P. Marketing Laboratory E. Stroudsburg PA 18301 Sturbridge MA 01566 562 Bunker Court Dick Guidoboni, President (570)421-7500 (508)248-1462 Vernon Hills IL 60061-1831 23 Depot Street (570)421-8735 (508)248-1463 (847)557-0603 Merrimack NH 03054 www.pkblenders.com www.remspec.com (847)680-1199 (603)429-9500 [email protected] [email protected] www.bohdan.com (603)429-9471 97 169 [email protected] www.northernanalytical.com Photon Technology Intl. RICCA Chemical Company 127,146 [email protected] Charles M. Phillips Coia Gary

The Nucleus October 2001 21 COMPANY DIRECTORY

North East Territory Manager www.ustesting.sgsna.com www.taylortechnologies.com 19 Ox Bow La. 6 Industrial Road [email protected] customerservice@taylortechnolo Summit NJ 07901 Pequannock NJ 07440 65A gies.com (908)273-0440 (973)694-0500 Shuster Laboratories 12A (973)694-7199 (908)273-2956 Patricia Baressi Thar Designs www.iconisotopes.com www.riccachemical.com Director, Marketing Comm. Todd Palcic [email protected] 85 John Rd. Sales and Marketing Mgr. [email protected] 39 Canton MA 02021 100 Beta Drive 12D Robertson Microlit Labs Inc. (781)821-2200 Pittsburgh PA 15238 United Chemical Tech. John Santa Cruz (781)821-9266 (412)967-5665 Ann Coyne, Product Manager Director Corporate Affairs shusterlabs.com (412)967-9446 P.O. Box 927 23 www.thardesigns.com 2731 Bartram Rd. Bristol PA 19007 Madison NJ 07940 Solv-Tek [email protected] (973)966-6668 Gene Stanton, President 77 (215)781-9255 (973)966-0136 216 Lewisville Road The Nest Group, Inc. (215)785-1226 www.robertson-microlit.com Berryville VA22611 Amos Heckendorf www.unitedchem.com [email protected]. net (540)955-4677 45 Valley Road [email protected] 20 (540)955-2018 Southborough MA 01772 46A www.solvtek.com (508)481-6223 Rudolph Instruments [email protected] (508)485-5736 United Products & Dr. K. Utukuri, President 132 www.nestgrp.com Instruments 40 Pier Lane Sopra Inc. [email protected] Sheridan Haggerty, Director Fairfield NJ 07004-2113 44 (973)227-0139 Jean Claude Fouere 182-E Ridge Rd. (973)227-4576 General Manager Thermo Galactic Dayton NJ 08810 www.rudolphinst.com PO Box 769, 323 Littleton Rd. Michelle Sharron (732)274-1155 Westford MA 01886 Marketing Supervisor [email protected] (732)274-1151 8 (978)392-2089 395 Main Street (978)392-9076 Salem NH 03079 unicol.com Schwarzkopf www.sopra-sa.com (603)898-7600 [email protected] Microanalytical [email protected] (603)898-6228 100,144,176 Florence Wohl, Exec. V. P. 176 www.thermogalactic.com 56-19 37th Ave. [email protected] Valco Instruments Co., Inc. Woodside NY 11377 Spex CertiPrep Beau Franke, Marketing Dept. William Fithian, Vice President 21 (718)429-6248 P.O. Box 55603 (718)429-5785 203 Norcross Avenue Thermo Nicolet Corp. Houston TX 77255 [email protected] Metuchen NJ 08840 Kathy Callaghan 12G,20,23,24,77,80,81,90,145, (800)522-7739 Marketing Communications (713)688-9345 147,151 (732)603-9647 Spec. (713)688-3948 www.spexcsp.com 5225 Verona Rd. www.vici.com Scientific Bindery [email protected] Madison WI 53711 [email protected] Nancy McDonald 104 (800)201-8132 Administrative Asst. (608)273-5046 11,41,138 60 East 13th Street Spex Fluorescence (JY) www.thermonicolet.com Chicago IL 60605 3880 Park Ave. VHG Labs [email protected] (312)939-3449 Edison NJ 08820 Mike Travers 169 (312)939-3787 (732)494-8660 Sales & Mktg Manager www.scientificbindery88yrs.com (732)549-5157 Thermo Spectra-Tech Inc. 180 Zachary Road #5 www.jyhoriba.com Aimee Devlin [email protected] Manchester NH 03103 163 [email protected] Sales & Marketing Asst. 167 230 Long Hill Cross Road (603)622-7660 Setra Systems, Inc. (603)622-5180 David Edwards Strem Chemicals, Inc. Shelton CT 06484-6225 Product Marketing Manager Ephraim Honig (203)946-8998 www.vhglabs.com 45 Nagog Park VP Marketing & Sales (203)926-8909 [email protected] Acton MA 01720 7 Mulliken Way, Dexter Inds. Pk www.thermospectra-tech.com 24 Newburyport MA 01950-3104 [email protected] (978)263-1400 Wyssmont Co., Inc. (978)264-0292 (978)462-3191 144 www.setra.com (978)465-3104 Tyger Scientific Inc. Joseph Bevacqua [email protected] www.strem.com Adam Yuan, Marketing Manager Marketing Manager 51 [email protected] 324 Stakes Avenue 1470 Bergen Blvd. SGS U.S. Testing Company, 27 Ewing NJ 08638 Fort Lee NJ 07024 Inc. Taylor Technologies Inc. (609)434-0144 (201)947-4600 (609)434-0143 Joe Kwiatkowski Patricia Fitzgerald, (201)947-0324 V.P. Marketing tygersci.com Director, Chemical Services www.wyssmont.com 291 Fairfield Avenue 31 Loveton Circle [email protected] Fairfield NJ 07004 Sparks MD 21152 28 [email protected] (973)575-5252 (800)837-8548 U.S. Services, Inc. 107 (973)244-1823 (410)771-4291 John Kilby, Marketing Manager

22 The Nucleus October 2001 PRODUCTS AND SERVICES ANALYTICAL CHEMICAL 35-ISOTOPES 60-RESEARCH EQUIPMENT ANALYSIS Cambridge Isotope Laboratories Activated Carbon Services Inc. ICON (Isotope) Services Inc. 61-TECHNICAL WRITING 3-DENSITOMETERS 18-BIO-ANALYSES BY 35A-PHARMACEUTICAL CAPTAN Associates, Inc. Cargille Laboratories HPLC INTERMEDIATES Mettler-Toledo, Inc. Chemir/Polytech Laboratories Front Run OrganX, Inc. CONSULTING 5-MOISTURE 19-BIOANALYTICAL Lancaster Synthesis SERVICES ANALYZERS GOW-MAC SERVICE LC/MS 37-REAGENTS Instruments Co. Chemir/Polytech Laboratories Eastern Chemical Div Unt Guard 64-CHEMICAL PROCESS Hiden Analytical HT Laboratories, Inc. Lancaster Synthesis Front Run OrganX, Inc. Mettler-Toledo, Inc. 20-CERTIFICATES OF 39-SOLUTIONS, 65-CONTRACT 7-PH METERS & ANALYSIS STANDARD RESEARCH INDICATORS Chemir/Polytech Laboratories Accustandard Inc Armbruster Associates Inc. Analytical Measurements Complete Analysis Laboratories Cambridge Isotope Laboratories Front Run OrganX, Inc. Mettler-Toledo, Inc. Robertson Microlit Labs Inc. RICCA Chemical Company Goldstein Associates Schwarzkopf Microanalytical 8-POLARIMETERS 65A-CONTRACT Rudolph Instruments 21-DATA PROCESSING CHROMATOGRAPHY TESTING LABORATORY National Institute Stds &Tech 9-REFRACTOMETERS 41-ACCESSORIES & Chemir/Polytech Laboratories Thermo Galactic Chromak Research, Inc. Cargille Laboratories SUPPLIES Libra Technologies, Inc. 23-TESTING Alpha Omega Technologies Inc. Mettler-Toledo, Inc. Micron Inc. LABORATORY D.C. Scientific LLC Oneida Research Services, Inc. 10-SURFACE AREA Chemir/Polytech Laboratories Valco Instruments Co., Inc. ANALYZERS Chemtest Laboratories SGS U.S. Testing Company Inc. 42-COLUMNS, First Ten Angstroms Micron Inc. 68-FORENSIC ANALYSES Schwarzkopf Microanalytical PREPACKED Cargille Laboratories 11-SYRINGES Alpha Omega Technologies Inc. Shuster Laboratories Chemir/Polytech Laboratories Valco Instruments Co., Inc. Astec 24-TRACE ELEMENT Chromak Research, Inc. 11A-TITRATION D.C. Scientific LLC ANALYSIS Brinkmann Instruments, Inc. 42A- 69-INFRARED ANALYSES Chemir/Polytech Laboratories Chemir/Polytech Laboratories Mettler-Toledo, Inc. Northern Analytical Laboratory CHROMATOGRAPHY Micron Inc. Chiral Technologies, Inc. 12-VISCOMETERS Schwarzkopf Microanalytical 72-NMR ANALYSIS Brookfield Engineering Lab Inc VHG Labs 43-GAS Chemir/Polytech Laboratories Cargille Laboratories 25-THERMAL ANALYSIS GOW-MAC Instruments Co. NMR Analysis & Consulting 12A-WATER TEST KITS Chemir/Polytech Laboratories 44-HPLC COLUMNS Numare Spectralab Inc. Taylor Technologies Inc. Hiden Analytical Alpha Omega Technologies Inc. 74-ORGANIC 12B-WEIGHING Matech Associates D.C. Scientific LLC Mettler-Toledo, Inc. Jordi Associates CHEMISTRY Business Development Intnl. BALANCES & SCALES Micron Inc. Princeton-Chromatography, Inc. Mettler-Toledo, Inc. The Nest Group, Inc. Goldstein Associates CHEMICALS 47-THIN LAYER 74B-PHARMACEUTICAL ANALYTICAL D.C. Scientific LLC ANALYSIS SERVICES 25A-AMINO ACIDS Chemir/Polytech Laboratories Cambridge Isotope Laboratories COATINGS 75-POLYMERS 12C-HPLC Lancaster Synthesis Business Development Intnl. Chemir/Polytech Laboratories 26-CATALYSTS 51-PRESSURE Chemir/Polytech Laboratories Chromak Research, Inc. Lancaster Synthesis TRANSDUCERS Goldstein Associates Jordi Associates 27-CHIRAL CATALYSTS Setra Systems, Inc. 76-PRODUCT 12D-MASS Lancaster Synthesis FORMULATION SPECTROMETRY Strem Chemicals, Inc. COMPUTER Chemir/Polytech Laboratories Chemir/Polytech Laboratories 28-CUSTOM SYNTHESIS APPLICATIONS Goldstein Associates Hiden Analytical Cambridge Isotope Laboratories 54-INFORMATION 77-R & D HT Laboratories, Inc. Dannier Chemical, Inc. Chromak Research, Inc. U.S. Services, Inc. Front Run OrganX, Inc. RETRIEVAL & REVIEW BIOSIS Front Run OrganX, Inc. 12F-TLC Lancaster Synthesis Goldstein Associates Chemir/Polytech Laboratories Tyger Scientific Inc. 56-SOFTWARE Hydro Slip Technologies, Inc. Acquisition Solutions 12G-UV-VISIBLE 29-DETERGENTS Schwarzkopf Microanalytical Alconox Inc. CambridgeSoft Corp Thar Designs Molecular Knowledge Systems Chemir/Polytech Laboratories 30-DYES AND STAINS 78-RADIATION Schwarzkopf Microanalytical Lancaster Synthesis PROCESSES CONSULTING, Armbruster Associates Inc. 33-INORGANIC MANAGEMENT BIOTECHNOLOGY CHEMICALS CAPTAN Associates, Inc. 13-BIOCHEMICALS CERAC,Inc. 58-MARKET RESEARCH 80-SPECTROSCOPY Cambridge Isotope Laboratories Lancaster Synthesis Business Development Intnl. Schwarzkopf Microanalytical

The Nucleus October 2001 23 COMPANY DIRECTORY

CONSULTING FURNITURE, LAB 138-VALVES SAFETY Hiden Analytical SERVICES Continnued 92-FURNITURE, LAB Valco Instruments Co., Inc. 156-EQUIPMENT Kewaunee Scientific Equipment Lab Safety Supply Co. 80A-TECHNOLOGY 138A-VIBRATION TRANSFER ISOLATION EQUIPMENT Business Development Intnl. GENERAL Kinetic Systems DOCUMENTATION Poly(Chem-Tech) EQUIPMENT 163-STOCK LAB BOOKS 80B-TESTING 97-BLENDERS, MIXERS, MICROSCOPES & Scientific Bindery LABORATORY STIRRERS SERVICES Chemir/Polytech Laboratories Patterson-Kelley SPECTROMETERS Micron Inc. 144-MICROSCOPE 98-BURETS & 81-UV ANALYSIS ACCESSORIES 167-FLUORESCENCE Schwarzkopf Microanalytical ACCESSORIES Cargille Laboratories ISS IKA Works Mettler-Toledo, Inc. McPherson, Inc. DETECTORS 99-CALORIMETERS Thermo Spectra-Tech Inc. Photon Technology Intl. Mettler-Toledo, Inc. United Products & Instruments Spex Fluorescence (JY) 84A-DISCHARGE 100-CENTRIFUGES 168-GRATINGS IONIZATION United Products & Instruments ORGANIC Hellma Cells GOW-MAC Instruments Co. 101-CLEAN AIR FUME MICROANALYSIS 169-IR 85-FLAME IONIZATION Digilab HOODS 145-ORGANIC Alpha Omega Technologies Inc. Bel-Art Products Remspec Corporation GOW-MAC Instruments Co. MICROANALYSIS Thermo Nicolet Corp. 104-CRUSHERS & Complete Analysis Laboratories 86-GAS LEAK GRINDERS 171-IR & UV CELLS GOW-MAC Instruments Co. Desert Analytics Hellma Cells IKA Works Huffman Laboratories, Inc. 87-THERMAL Spex CertiPrep 172-MASS Schwarzkopf Microanalytical Nanmac Corporation 105-PC’S DELL Alpha Omega Technologies Inc. Hiden Analytical 87A-THERMAL Bio-Cellular Science Inc. ORGANIC CONDUCTIVITY 107-DRYERS 176-UV VISIBLE GOW-MAC Instruments Co. Wyssmont Co, Inc. SYSTHESIS Control Development Hellma Cells 107A-DUCTLESS FUME 146-ORGANIC Sopra Inc. ELECTRON HOODS SYSTHESIS United Products & Instruments Frinton Laboratories, Inc. MICROPROBE Captair Labs, Inc. 178-X-RAY 109-EVAPORATORS Front Run OrganX, Inc. 88-ELECTRON Mettler-Toledo Bohdan, Inc. FLOURESCENCE MICROPROBE Heidolph Instruments Oxford Instruments Micron Inc. 111-FLOW METERS ORGANOMETALLICS Controltron Corp EDUCATION & ELECTRON 114-GENERAL 147- PUBLICATIONS MICROSCOPY LABORATORY ORGANOMETALLICS EQUIPMENT Schwarzkopf Microanalytical 179B-TRAINING & 89-ELECTRON IKA Works EDUCATION MICROSCOPY POLLUTION American Inst. of Chemists,Inc 116-GLASSWARE Excel for Scientists&Engineers Micron Inc. Kimble/Kontes CONTROL Lehigh Univ Distance Educa Of Q-Glass Co Inc. PACS Courses and Conferences ENVIRONMENTAL Quartz Plus Inc. 149-STANDARDS Cambridge Isotope Laboratories ANALYSIS 119A-LABWARE 90-ENVIRONMENTAL Cargille Laboratories RADIATION 121-NIR COMPOSITION ANALYSIS EQUIPMENT Chemir/Polytech Laboratories ANALYZERS Complete Analysis Laboratories Instrument Distributors Int’l 152-RADIATION Lancaster Laboratories Inc. 132-SOLVENT EQUIPMENT Schwarzkopf Microanalytical PURIFICATION Nuclear Associates SYSTEMS ESCA SERVICES Solv-Tek RADIATION 91-ESCA SERVICES 133- PROCESSES Chemir/Polytech Laboratories SPECTROPHOTOMETER CELLS 153-RADIATION Hellma Cells PROCESSES Armbruster Associates Inc. 137-VACUUM EQUIPMENT Hiden Analytical

24 The Nucleus October 2001 October 24 Calendar Prof. Dan Reger (Univ. of South Carolina) DIRECTORY Continued from page 28 tba Seminar MIT, Room 6-120, 4:00 pm “The Chemistry & Biology of Novel, Dual- Acting 5-Lipoxygenase Inhibitors and H1 Prof. Wilfredo Colon (Rensselaer Polytechnic SERVICES Receptor Antagonists for Treatment of Asthma” Institute) Univ. Mass. Boston, Science Building, Room “Deciphering the 'grammatical rules' of protein 089, 4:30 pm folding” UMass Dartmouth, Science & Engineering October 17 Building (Group II), Room 115, 4:00 pm Prof. E. J. Corey (Harvard Univ.) University Lectures in Chemistry 2001-2001 October 25 “Catalytic Enantioselective Synthesis: Methods, Dr. Verna Frasca (MicroCal, LLC) Pathways and Applications” Part Two “Microcalorimetric Methods for the Detection Boston College, Merkert Chemistry Center, and Analysis of Biomolecules” Room 130, 2609 Beacon St. 4:00 pm Am. Association for Clinical Chemistry and the Clinical Ligand Assay Society, at Prof. G. Coates (Cornell Univ.) West Roxbury V.A. Hospital, Research TBA Inorganic Chemistry Seminar Conference Room 2B-100, 3:30 pm MIT, Room 6-120, 4:00 pm Prof. Takeshi Nakai (Niigata Univ.) Prof. D. Venkataraman (U. Mass. -Amherst) Organic Chemistry Seminar Series: Organic “Copper-based Catalysts for Aryl-carbon and Syntheses, Inc., Lecture Aryl-Heterobond Formation” MIT, Room 6-120, 4:00 pm UMass Dartmouth, Science & Engineering Building (Group II), Room 115, 4:00 pm October 29 Prof. Patrick Vaccaro (Yale Univ.) October 18 “Spectroscopic Investigations of Proton-Transfer Dr. George Klee (The Mayo Clinic) and Hydrogen-Bonding in Model Organic “Human Anti-Mouse Antibody” Systems” Am. Association for Clinical Chemistry and the Boston Univ., Science Center Auditorium, Clinical Ligand Assay Society, at SCI 107, 4:00 pm Doubletree Guest Suites Hotel, Waltham at 128 6 pm Social; 7 pm Dinner; 8 pm Lecture Prof. Sunny Xie (Harvard Univ.) TBA Prof. Christopher Dobson (Oxford Univ.) Brandeis Univ., A.D. Little Lecture in Physical Chemistry; Room Gerstenzang 122, Building Edison Lecks, (Harvard/MIT) Physical Chem. Lecture 4:00 pm “Protein Misfolding and Its Links with Human Disease” MIT, Room 6-120, 5:00 pm (not 4 pm) Prof. Ernesto Carmona-Guzman (Universidad de Sevilla) Prof. Gary E. Wnek (Virginia Commonwealth TBA A.D. Little Lecture in Inorganic Chemistry Univ.) MIT, Room 6-120, 4:00 pm “Thinking Small about Old Polymers at the Medicine/Engineering Interface” Worcester Polytechnic Institute, Dept. of October 30 Chemical Engineering, Dr. Takeshi Nakai (Tokoyo Institute) Goddard Hall, Room 227, 4:00 pm TBA Brandeis Univ., Room Gerstenzang 122, October 19 Building Edison Lecks, 4:00 pm Prof. E. J. Corey (Harvard Univ.) Prof. Ernesto Carmona-Guzman (Universidad de University Lectures in Chemistry 2001-2001 Sevilla) “Catalytic Enantioselective Synthesis: Methods, TBA A.D. Little Lecture in Inorganic Chemistry Pathways and Applications” Part Three MIT, Room 6-120, 4:00 pm Boston College, Merkert Chemistry Center, Prof. Andrei Tokmakoff (Mass. Inst. of Tech.) Room 130, 2609 Beacon St., 4:00 pm “Molecular Structure and Dynamics in Solution Observed through Two-Dimensional October 23 Infrared Spectroscopy” Prof. Xiaowei Zhuang (Harvard Univ.) Tufts Univ., Pearson Chem. Building, 62 Talbot “Watching Enzymes Fold and Function One Ave., Medford, Room 106, 4:30 pm Molecule at a Time” Prof. Iwao Ojima (SUNY Stony Brook) MIT, Room 2-105, 4:00 pm “Interface of Organic Synthesis and Medicine: Prof. Peter Lansbury, Jr. (Harvard Medical From Enzyme Inhibitors to Taxol” School and Brigham and Women's Univ. Mass. Boston, Science Building, Room Hospital) 089, 4:30 pm “The Emergence of New Therapeutic Targets for Parkinson's Disease” October 31 Tufts Univ., Pearson Chem. Building, 62 Talbot Jenn Jamieson (Schrock Group) Ave., Medford, Room 106, 4:30 pm TBA Inorganic Chemistry Seminar Prof. Carolyn Anderson (Washington Univ., St. MIT, Room 6-120, 4:00 pm Louis) Prof. Donald W. Boerth (UMass Dartmouth) Topic to be announced “Nucleophilic Substitution Reactions by Univ. New Hampshire, Iddles Auditorium Room Glutathione in Chlorinated Aromatic L103, 11:10 am Systems - an Ab Initio Investigation” UMass Dartmouth, Science & Engineering Building (Group II), Room 115, 4:00 pm The Nucleus October 2001 25 BUSINESS DIRECTORY

SERVICES SERVICES SERVICES

26 The Nucleus October 2001 BUSINESS DIRECTORY

CAREER OPPS CAREER OPPS SERVICES

Index of Advertisers Am. Instrument Exchange...... 25 Am. Polymer Standards Corp...... 26 Cambridge Isotope ...... 27 Chemir/Polytech Laboratories...... 27 Chemo Dynamics LP ...... 8 CNH Technologies, Inc...... 26 Desert Analytics Laboratory...... 26 Eastern Scientific Co...... 14 Front Run Organx...... 26 Jordi Associates, Inc...... 25 Kelly Scientific Resources ...... 12 Lab Support...... 18 Mass-Vac, Inc...... 2 Micron Inc...... 26 NuMega Resonance Labs...... 26 Organix, Inc...... 25 Prime Organics...... 26 Quantitative Technologies, Inc.....26 Robertson Microlit Labs, Inc...... 15 RSP Amino Acid Analogues, Inc. ..6 Schwarzkopf Microanalytical ...... 25 Scientific Bindery...... 26 Spectral Data Services, Inc...... 25 Surfaces Research ...... 26 University of New Hampshire...... 9 Yasui Seiki Co...... 26

The Nucleus October 2001 27 avr,M 01451 Harvard, MA 19 Mill Road

Paul Henderson (Essigmann Group, MIT) October 10 Biochemistry Seminar “Biophysical Causes Prof. Robert Bergman (Univ. of California, and Mutagenic Consequences of Guanine Berkeley) Oxidation in DNA” tba Inorganic Chemistry Seminar MIT, Room 6-120, 4:00 pm MIT, Room 6-120, 4:00 pm Prof. Joseph Helble (Univ. of Connecticut) “Fine Particulate Air Pollution and Human October 11 Health: The Contribution of Combustion Dr. Robert Barrows (New England Biometrics) Sources” “Faster Assay Development with Statistical Tufts Univ., Dept. of Chem. & Biological Experimental Design” Engineering, The Clinical Ligand Assay Society, at Genetics 4 Colby Street, Science & Technology Center, Institute, 6th Floor, Room 136, 11:30 am 150 Cambridge Park Drive, Cambridge, 6:00 pm (5:30 pm refreshments) October 2 Prof. Kai Yee Lee (Univ. of Chicago) Prof. Peter Seeberger (Mass. Inst. of Tech.) Physical Chem. Lecture “Automated Synthesis of Oligosaccharides:New Harvard Univ., MB-23 Pfizer Lecture Hall, 5pm Chemistry to Address Fundamental Biomedical Questions “ Prof. Carl R. F. Lund (SUNY Buffalo) Tufts Univ., Pearson Chem. Building, 62 Talbot “An Experimental and Computational Ave., Medford, Investigation of Redox Cycles during Room 106, 4:30 pm N2O Decomposition” Worcester Polytechnic Institute, Dept. of AMERICAN CHEMICAL Prof. John McDonald (Worcester Polytechnic U.S. POSTAGE PAID Chemical Engineering, OPOI ORG. NONPROFIT NORTHEASTERN Institute) Goddard Hall, Room 227, 4:00 pm SOCIETY SECTION “Design of Crystalline Materials” Univ. Mass. Boston Science Building, Room 089, 4:30 pm October 12 Prof. Dieter Seebach (ETH Zurich) Organic Chemistry Seminar Series: October 3 Wyeth-Ayerst Lecture Prof. Judith Herzfeld (Brandeis Univ.) MIT, Room 6-120, 4:00 pm “Solid-state NMR Studies of the Proton Pump Cycle of Bacteriorhodopsin” UMass Dartmouth, Science & Engineering October 15 Building (Group II), Prof. William Goddard (Calif. Institute of Calendar Technology) Room 115, 4:00 pm “De novo Simulations of Catalysis, Materials, For additional information, call: and Biochemistry” Am. Assoc. Clinical Chemists - (617) 732-6987, October 4 Boston Univ., Science Center Auditorium, SCI pager 11161 Prof. Dr. Peter Chen (ETH Zentrum) 107, 4:00 pm Boston College - (617) 552-2605 Topic to be announced Boston University - (617) 353-4277 Boston College, Merkert Chemistry Center, Prof. Christopher Dobson (Oxford Univ.) Brandeis University - (781) 736-2500 Room 127, 2609 Beacon St. A.D. Little Lecture in Physical Chemistry Dartmouth College - (603) 646-2501 4:00 pm “The Nature and Significance of Protein Harvard University - (617) 495-4198 Folding” Prof. R. Dean Autsmian (Univ. of Maine, Dept. MIT, Room 6-120, 4:00 pm Mass. Inst. Technology - (617) 253-1803 of Physics) Northeastern University - (617) 373-2822 Opening Reception in the Moore Room, 6-321 (Harvard/MIT) Physical Chem. Lecture at 5:30PM Tufts Univ. - (617) 627-2634 Harvard Univ., MB-23 Pfizer Lecture Hall, 5 pm UMass Boston - (617) 287-6130 Prof. Theresa Wood (Texas A & M Univ.) UMass Dartmouth - (508) 999-8232 Prof. Thomas J. Wandless (Stanford Univ.) “Using Engineering Tools to Examine UMass Lowell - (978) 934-3675 tba Seminar in Organic Chemistry Mechanisms of Amyloid Diseases” Univ. of New Hampshire - (603) 862-1550 MIT, Room 6-120, 4:00 pm Tufts Univ., Dept. of Chem. & Biological Worcester Polytechnic Institute - (508) 831-5250 Prof. Patricia Maurice (Notre Dame Univ.) Engineering, Check NESACS Homepage for late additions: “Molecular-Scale Approaches to Organic-Matter 4 Colby Street, Science & Technology Center, http://www.NESACS.org Interactions with Mineral Surfaces” Room 136, 11:30 am Note also the MIT Chemistry Department Worcester Polytechnic Institute, Dept. of Webpage calendar: http://web.mit.edu/chemistry/ Chemical Engineering, October 16 www/temp/seminars/pchemseminars.html Goddard Hall, Room 227, 4:00 pm Prof. E. J. Corey (Harvard Univ.) and the Harvard Chemistry web site for updates: University Lectures in Chemistry 2001-2001 http://www-chem.harvard.edu/events/Physical_ October 9 “Catalytic Enantioselective Synthesis: Methods, Seminars.html Dr. Marshall Newton (Brookhaven National Pathways and Applications” Part One (which includes the Harvard/MIT joint seminars) Laboratory) Boston College, Merkert Chemistry Center, “Mechanisms of Thermal and Optical Electron Room 130, 2609 Beacon St. 4:00 pm October 1 Transfer: Perspectives from Theory Prof. Christopher Dobson (Oxford Univ.) Prof. Nicholas Farrell (Virginia Commonwealth and Computation” A.D. Little Lecture in Physical Chemistry Univ.) MIT, Room 2-105, 4:00 pm “Unravelling the Mechanisms of Protein Folding “Polynuclear Platinum-DNA Interactions: New Ms. Lisa Lloyd Kindstrand (U. Mass. - Boston) Reactions” Classes of Antitumor Drugs” Literature Seminar, “Diamonds and Dust: K/T MIT, Room 6-120, 4:00 pm Boston Univ., Science Center Auditorium, SCI Boundary Clay Analysis” Prof. Catherine Drennan (Mass. Inst. of Tech.) 107, 4:00 pm Univ. Mass. Boston “When Bigger Isn't Better: Crystal Structure of Prof. Alex Tropsha (Univ. of North Carolina) Science Building, Room 089, 4:30 pm Class II Ribonucleotide Reductase” “Computational Geometry (Delaunay Prof. Watson L. Lees (Syracuse Univ.) Tufts Univ., Pearson Chem. Building, 62 Talbot Tessellation) of Proteins: From Topic to be announced Ave., Medford, Structure to Sequence to Function” Univ. New Hampshire, Iddles Auditorium Room Room 106, 4:30 pm Brandeis Univ., Room Gerstenzang 122, L103, 11:10 am Dr. Ralph Scannell (Union Chimique de Building Edison Lecks, Belgique) 4:00 pm Continued on page 25 October 2001 Overflow

rely on ancient manuscripts containing (The original article contains a plate in highly stylized figures and on the texts color which cannot be reproduced Book Review of the 16th and 17th centuries, which here). The glassware in the figure sug- Apparatus and Acumen were often stylized versions of these gests alchemy, not simply the assaying Instruments and stylized pictures, in some cases proba- or weighing of gemstones. Thus the Experimentation in the bly describing apparatus fabricated quantitative analytical work of only in the mind of the author. alchemists may have been more History of Chemistry. Edited by Following a helpful introduction sophisticated than is generally Frederic L. Holmes and Trevor H. by the editors are 14 contributed chap- assumed. Levere. xxii + 415 pp. The MIT Press, ters organized chronologically into Lawrence M. Principe (in “Appa- 2000. $50. three sections: The Practice of ratus and Reproducibility in Reviewed by Arthur Greenberg, Col- Alchemy; From Hales to the Chemical Alchemy”), arguing against Jungians Revolution; and The Nineteenth and who attribute alchemical imagery to lege of Engineering and Physical Sci- Early Twentieth Centuries. The editors psychic states, makes a case for precise ences, University of New Hampshire, also introduce each section with a brief chemical apparatus as an indicator of Durham explanatory essay. The chapters, 20 to the reproducibility desired by Reprinted by permission from Ameri- 40 pages in length, are uniformly well chrysopoeians (alchemists devoted to can Scientist, 2001, 89, 372-374. written and well edited, and most are making gold). Evidence includes a dis- well illustrated. They are written both cussion of the symbols in the keys of for chemical historians and for a more Basil Valentine, presumably readily Humphrey Davy held the early general readership, since unfamiliar decipherable by any true adept. One “world's record” for discovering chem- terms are defined, and often the very interesting feature of this chapter ical elements’ six. In Elements of workings of unfamiliar apparatus are is Principe's experimental recreation of Chemical Philosophy, he modestly explained. Each chapter ends with an a “Philosopher's tree” inside a glass attributed his success to the extremely useful summary. flask. Ð a new instrument in the chemist's The first chapter (“The Archaeol- In “Slippery Substances,” Maurice armamentarium Ð rather than to his ogy of Chemistry”), by Robert G. W. Crosland neatly explains how and why own acumen, stating that “The active Anderson, summarizes the discoveries chemists were so unconcerned with intellectual powers of man in different of fragments of ancient chemical glass- gases until the work of Stephen Hales times are not so much the cause of the ware from Egypt, Arab lands, India, and thoroughly depicts the evolution of different successes of their labours, as early Europe and Renaissance Europe. studies of gases through the 18th cen- the peculiar nature of the means and Four important early books are scruti- tury. artificial resources in their posses- nized for details of Renaissance chemi- Trevor H. Levere (in “Measuring sions.” cal practices. It is both humbling and Gases and Measuring Goodness”) Histories of chemistry usually reassuring to note the relative “stabil- treats the long-forgotten eudiometer, trace the evolution of great ideas or the ity” of chemical glassware and “conti- initially developed by Joseph Priestley interplay between great scientists. The nuity” of change through the ages. as a volumetric instrument for measur- essays in this collection examine the However, Anderson cautions us not to ing the purity of “dephlogisticated air” evolution of the field through its appa- take these texts at face value, noting as well as the “goodness of air” ratus. This presents an interesting chal- that much more may eventually be through reaction with nitric oxide. This lenge since, unlike the attractive and learned from careful study of the instrument quickly evolved to include robust microscopes, telescopes and archaeological fragments. sparking wires and in other ways to astrolabes of earlier centuries, chemi- In “Alchemy, Assaying, and make it suitable for testing other cal apparatus was more modest, even Experiment,” William R. Newman gaseous reactions. The illustrations of homely, and especially more fragile makes a case for the very early use of gasometers, which fed measured and, therefore, highly disposable and the blowpipe for chemical investiga- amounts of gases into reactions, disposed of. Its more valuable parts tions Ð well before its employment by include the elaborate apparatus of (such as metal rings) were stripped and Johann Kunckel in the 17th century. Antoine Laurent Lavoisier recycled. Thus, little ancient al chemi- Quantitative accuracy in alchemical Lavoisier's wealth and precision cal glassware exists today; for exam- investigation, commonly unantici- afforded him a laboratory of unrivaled ple, the number of true pelicans pated, is implied by the famous glass- apparatus. Frederic L. Holmes (“The (glassware for recycling distillation) cased balance in Elias Ashmole's 1652 Evolution of Lavoisier's Chemical that have survived is quite small. We Theatrum Chemicum Britannicum continued on page 30 Saltus: This page does not Print

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ple proportions. , whose him eventually to exchange the title of Book Review experiments verified his theory, did not professor of physical chemistry for a Continued from page 29 provide experimental support as strong chair of “social studies” at Manchester. Apparatus”) quotes Jan Golinski's as that of William Hyde Wollaston, This book is a must for all institu- observation that “To Priestley and his who had no theoretical bias. The tional libraries and for anyone even followers, expenditure on this scale strongest experimental evidence was mildly interested in the history of was not only undesirable but reprehen- contributed by Jacques Étienne Bérard, chemistry. sible, because it foreclosed the possi- who received the least recognition, bility of Lavoisier's experiments being because the theory was already gener- replicated by others who lacked his ally accepted. wealth.” A key insight offered to the In “Organic Analysis in Compara- reader is that most of Lavoisier's great tive Perspective,” Alan J. Rocke pro- works were actually accomplished vides an excellent description of Justus using relatively simple apparatus, often Liebig's development of the Kaliappa- adapted or “jerry-rigged” from earlier rat, which permitted the gravimetric pieces. measurement of carbon dioxide from Bernadette Bensaude-Vincent large quantitities of organic com- (“The Chemist's Balance For Fluids”) pounds, thus revolutionizing the accu- treats hydrometers and their cousins racy of carbon, hydrogen and oxygen areometers. Thought initially to have analysis. His accounts of Liebig's inter- great potential as scientific instru- actions with Jacob Berzelius, Friedrich ments, hydrometers were useful for Wöhler and Jean Baptiste Dumas are measuring the “goodness” of wine, informative and entertaining. Liebig among other commercial liquids. was skeptical of Dumas's “French Jan Golinski (“Fit Instruments”) chemistry,” but Dumas ultimately per- reminds us of the important role Her- fected the difficult analysis of nitrogen. man Boerhaave played in transforming “Chemical Techniques in a Pre- the thermometer from an instrument electronic Age,” by Colin A. Russell, used to quantify our senses (a “cool” treats the ingenious chemical apparatus breeze has the same temperature as designed by Edward Frankland in the motion-less air) into a scientific instru- latter half of the 19th century. Trying ment both used on its own and incor- to trap the radical “ethyl,” Frankland porated into more complex apparatus. made pyrophoric diethylzinc instead In “Platinum and Ground Glass,” and ushered in the era of organometal- William A. Smeaton describes Louis lic chemistry. Bernard Guyton de Morveau's The theme of Seymour H. Mauskopf's exploitation of these innovations in his “Bridging Chemistry and Physics in portable laboratory. The agronomist the Experimental Study of Gunpow- Arthur Young visited Guyton in Dijon der” is the use of physics to determine in 1789 and found “such a variety and the ballistic force of gunpowder. extent of apparatus, as I have seen The final chapter, “Laboratory nowhere else.” This apparatus was the Practice and the Physical Chemistry of standard for other such chemistry Michael Polanyi,” by Mary Jo Nye, “kits” on both sides of the Channel and provides a wonderfully focused across the Atlantic during the early description of the Hungarian Jew who 19th century. left the continent in the stormy and The final section begins with an dangerous aftermath of World War I to insightful essay by Melvyn C. Ussel- make seminal contributions to x-ray man (“Multiple Combining Propor- in Manchester in the tions”) that analyzes the experimental 1920s. His poly-mathic interests led work associated with the law of multi-

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30 The Nucleus October 2001