Authors: Pallavi Subhraveti Ron Caspi Peter Midford Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_000348125Cyc: Vibrio cholerae AG-7404 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari a dicarboxylate thiosulfate an amino an amino an amino (2-aminoethyl) gln sulfate agmatine arg a dipeptide an acid acid phosphate phosphate cefoperazone cefoperazone cefoperazone sulfate phosphonate asp arg cys thiamine ammonium ammonium a tripeptide acid an amino an amino an amino an amino an amino an amino an amino phosphate glucosyl-oleandomycin glucosyl-oleandomycin glucosyl-oleandomycin glu arg arg lactose phosphate phosphate glutathione sulfate sulfate ammonium acid acid acid acid acid acid acid diphosphate uracil D-cellobiose predicted L-ornithine predicted predicted predicted predicted predicted ABC predicted predicted predicted ATP-driven ABC ABC ABC ABC transporter of ABC ABC ABC RS01955 ThiP RS00930 RS06785 RS00380 RS13505 transporter RS02920 RS10235 RS14885 CadB ArtM RS09230 RS04615 RS01000 RS0117350 RS02830 RS01480 RS02010 RS05480 RS05485 RS00425 transporter transporter RS05200 RS00085 RS08260 RS14890 transporter RS04290 RS02380 RS12200 transporter (2-aminoethyl) transporter transporter transporter of sulfate/ of an of an of an of sulfate phosphonate of L-arginine of phosphate of phosphate thiosulfate amino acid amino acid amino acid cefoperazone cefoperazone cefoperazone uracil gln ammonium ammonium lactose 6'-phosphate phosphate cys thiamine glucosyl-oleandomycin glucosyl-oleandomycin glucosyl-oleandomycin a tripeptide an amino an amino an amino an amino an amino an amino an amino an amino sulfate sulfate asp arg arg arg ammonium D-cellobiose 6'-phosphate phosphate phosphate glutathione diphosphate acid acid acid acid acid acid acid acid (2-aminoethyl) glu agmatine a dipeptide thiosulfate sulfate arg an amino an amino an amino phosphate phosphate phosphonate L-ornithine a dicarboxylate sulfate acid acid acid

Cofactor, Prosthetic Group, Electron Carrier, and Vitamin

1-palmitoyl- 1-stearoyl- 6-cis, 3-oxo- DNA combined a ribonucleoside adenosine 1-myristoyl- a (1->4)- a (7Z,10Z,13Z 1-cis-vaccenoyl-sn- a purine an acyl-[acyl- glycerophosphoserine 3-phenyl-2- 1-(18-hydroxyoleoyl)- (S)-1-pyrroline- [2Fe-2S] iron- cluster biosynthesis superpathay of heme b Fatty Acid and Lipid Biosynthesis Fermentation mixed acid fermentation a palmitoleoyl-[acp] a malonyl-[acp] a palmitoleoyl-[acp] sn-glycerol a palmitoyl-[acp] sn-glycerol tyr with exogenous 2',3'-cyclic 2',3'-cyclic sn-glycerol α-D-glucan ,16Z,19Z)-3- superpathway of tetrahydrofolate biosynthesis superpathway of demethylmenaquinol-8 biosynthesis I flavin biosynthesis I ( and plants) ubiquinol-8 biosynthesis (prokaryotic) superpathway of adenosylcobalamin salvage from cobinamide I N 10 -formyl-tetrahydrofolate biosynthesis lipoate salvage I pyridoxal 5'-phosphate biosynthesis I lipoate biosynthesis glycerol-3-phosphate carrier ] tridecenoyl-CoA oxopropanoate sn-glycrol 3-phosphate 5-carboxylate ribonucleoside adenosylcobinamide 3-phosphate 3-phosphate acetyl-CoA C- phosphate monophosphate 1-pyrroline-5- 3-phosphate 1,4-alpha-glucan oxodocosa- biosynthesis from glutamate and incorporation II 1-acyl-sn-glycerol- beta-ketoacyl-[acyl- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- glycerophosphoryl aspartate/ 1-acyl-sn-glycerol- DNA to form a 2',3'-cyclic- multifunctional CCA 1-acyl-sn-glycerol- superpathway of purine deoxyribonucleosides degradation Nucleoside and Nucleotide Degradation 5'-triphosphate bifunctional acyltransferase FadI: diester recombinational carboxylate branching : 7,10,13,16,19- L- all-trans- D-erythrose palmitate biosynthesis II (bacteria and plants) phosphoenolpyruvate 3-phosphate carrier-protein] 3-phosphate 3-phosphate tyrosine/aromatic 3-phosphate Holliday junction 2'-phosphodiesterase: tRNA nucleotidyl 3-phosphate beta- chorismate cob(II)inamide a tetrahydrofolate (R)-lipoate palmitoleate biosynthesis I fatty acid elongation -- saturated adenosylcobinamide VCAG7404_RS02570 dehydrogenase: VCAG7404_RS07600 pentaenoyl-[acp] GTP 4-hydroxybenzoate octaprenyl glu 4-phosphate octanoate acyltransferase: synthase II: acyltransferase: acyltransferase: phosphodiesterase: aminotransferase: acyltransferase: junction resolvase RuvX: VCAG7404_RS11655 /2'3'-cyclic acyltransferase: ketoacyl- GTP lipoate--protein : (from (5Z)-dodec-5-enoate) / VCAG7404_RS07855 1,4-alpha-glucan- 4-hydroxybenzoatediphosphate lipoate--protein ligase: VCAG7404_RS14545 VCAG7404_RS14185 VCAG7404_RS14545 VCAG7404_RS14545 acetyl-CoA C- VCAG7404_RS00310 VCAG7404_RS10095 VCAG7404_RS14545 VCAG7404_RS05275 phosphodiesterase/ VCAG7404_RS14545 ACP cysteine desulfurase: isochorismate synthase: cob(I)yrinic acid VCAG7404_RS19260 D-erythrose- 2'-deoxyguanosine multifunctional CCA octaprenyltransferase: VCAG7404_RS19260 an acetoacetyl-[acp] PykF: phosphoenolpyruvate adenosylcobinamide- acyltransferase FadA: glycerophosphodiester 2'nucleotidase/ bifunctional proline branching protein: reductase: VCAG7404_RS12790 GTP cyclohydrolase VCAG7404_RS14380 GTP cyclohydrolase II: a,c-diamide [+ 2 isozymes] 4-phosphate a (5Z)-dodec- an acetoacetyl-[acp] 1-acyl-sn-glycerol- beta-ketoacyl-[acyl- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- aspartate/ 1-acyl-sn-glycerol- crossover junction tRNA nucleotidyl 1-acyl-sn-glycerol- a (3R,7Z,10Z VCAG7404_RS07080 [+ 2 isozymes] VCAG7404_RS05185 carboxylase: phosphate VCAG7404_RS10740 phosphodiesterase: dehydrogenase/L- VCAG7404_RS16700 fabG I FolE: VCAG7404_RS01580 3-octaprenyl-4- adenosyltransferase: an L-glutamyl- (lipoyl)adenylate dehydrogenase: a [lipoyl-carrier protein] 5-enoyl-[acp] 2'-deoxyadenosine 3-phosphate carrier-protein] 3-phosphate 3-phosphate tyrosine/aromatic 3-phosphate endodeoxyribonuclease transferase/2'3'-cyclic phosphatase: 3-phosphate ,13Z,16Z,19Z)-3- Glu beta-ketoacyl- beta-ketoacyl-[acyl- VCAG7404_RS11275 : 4-cis- an S-sulfanyl-[L- [tRNA ] 6 pyruvate kinase: synthase I: acyltransferase: acetyl-CoA VCAG7404_RS16435 aminotransferase: acyltransferase: VCAG7404_RS12180 glutamate gamma- a glycogen hydroxydocosa- VCAG7404_RS09630 isochorismate bifunctional 3,4- hydroxybenzoate VCAG7404_RS02600 methionine synthase: VCAG7404_RS05220 N -octanoyl-L-lysine ACP acyltransferase: acyltransferase: undecenoyl-CoA resolution of RuvC: phosphodiesterase/ acyltransferase: 7,8- lipoate--protein ligase: carrier-protein] VCAG7404_RS14235 purine degradation II (aerobic) a purine VCAG7404_RS01685adenosyl- sn-glycerol semialdehyde cysteine desulfurase] 3-octaprenyl-4- [corrinoid VCAG7404_RS05685 4-phospho- purine-nucleoside VCAG7404_RS118651-cis-vaccenoyl- VCAG7404_RS13770 VCAG7404_RS11865 VCAG7404_RS11865 ser 3-(4-VCAG7404_RS01435 1-[18-hydroxyoeoyl]-2-VCAG7404_RS11865 recombinationalVCAG7404_RS14960 2'nucleotidase/ 2',3'-cyclic-nucleotide VCAG7404_RS11865 7,10,13,16,19- dihydroxy-2-butanone- glutamyl-tRNA lipoyl synthase: reductase: fabG synthase