DOCSLIB.ORG

Rothamsted Repository Download

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Rothamsted Repository Download Patron: Her Majesty The Queen Rothamsted Research Harpenden, Herts, AL5 2JQ Telephone: +44 (0)1582 763133 WeB: http://www.rothamsted.ac.uk/ Rothamsted Repository Download G - Articles in popular magazines and other technical publications Lawlor, D. W. 2014. William Stanley Pierpoint (1930-2013). Portland Press Ltd. doi:10.1042/BIO03601056 The publisher's version can be accessed at: • https://dx.doi.org/10.1042/BIO03601056 The output can be accessed at: https://repository.rothamsted.ac.uk/item/96z50/william- stanley-pierpoint-1930-2013. © 1 February 2014, Portland Press Ltd. 25/11/2019 16:42 repository.rothamsted.ac.uk [email protected] Rothamsted Research is a Company Limited by Guarantee Registered Office: as above. Registered in England No. 2393175. Registered Charity No. 802038. VAT No. 197 4201 51. Founded in 1843 by John Bennet Lawes. Obituary William Stanley Pierpoint (1930–2013) Council at the Unit for Research in Cell [e.g. Jervis, L. and Pierpoint, W.S. (1989) Metabolism in Sheffield for a PhD with Hans Purification technologies for plant proteins. Krebs (he of the eponymous metabolic cycle Journal of Biotechnology 11, 161–198]. One title in the mitochondria), Nobel Prize Laureate encapsulates Stan’s wry humour ‘Phenolics in in 1953 and knighted in 1958. There Stan foods and feedstuffs: the pleasures and perils studied enzymes and metabolism mainly in of vegetarianism’. There were also many careful bacteria. On Krebs’ departure from Sheffield, experimental studies of cell components, Stan decided not to move with him and after phosphatases, phosphoesterases, ribonucleases Downloaded from https://portlandpress.com/biochemist/article-pdf/36/1/56/6265/bio036010056.pdf by UK user on 25 November 2019 the PhD in 1953 he joined the Biochemistry and N-acylamine acid acyclase, which were Department of Rothamsted Experimental of importance in DNA replication. There was Station, to work under William (‘Bill’) Pirie a very strong regard for scientific rigour in FRS (elected in 1949). Stan’s research, with considerable emphasis on As those with experience of Rothamsted solving technical problems, but always with the then and Bill Pirie attest, management and aim of using the methods to resolve a larger- equipment were minimal, but individualism scale scientific question. was encouraged and Stan was soon publishing, Another important interest of Stan’s lay in an activity he never gave up, writing in his understanding the effect on plant metabolism lucid and erudite English style on technical and of viruses and pathogens, a strong point in detailed science which gradually blossomed the Rothamsted of Pirie and the then director, to include science-derived and related topics Sir Frederick Bawden FRS. Stan’s pioneering of historical interest. In the early 1960s Stan work (in collaboration) led to identification (together with his wife Maureen and children) of specific proteins resulting from infections, Stan, as he was always known, joined had a 2-year sabbatical at the University of called pathogenesis-related proteins [Pierpoint, Rothamsted Experimental Station (now California, USA, with George Laties, forging W.S., Robinson, N.P. and Leason, M.B. (1981) Rothamsted Research), the agricultural a lifetime friendship. Stan served as the The pathogenesis-related proteins of tobacco: research institution in Harpenden, Membership Secretary of the Phytochemical their induction by viruses in intact plants and Hertfordshire, UK, in 1954 beginning a 36-year Society. their induction by chemicals in detached leaves. career as a research biochemist and a lifelong Moving to a department interested in Physiological Plant Pathology 19, 85–97]. Later, association with Rothamsted. Stan studied, leaf proteins and metabolism, Stan looked in retirement, this expertise led Stan to editing as he put it, “…biochemical entities, proteins, for the Krebs cycle and did important work, (together with Peter Shewry) and contributing viruses and organelles, extracted from plants, particularly in isolating mitochondria and a chapter in Genetic Modification of Crop Plants mainly mature green leaves”. A common theme demonstrating that they oxidized Krebs cycle for Resistance to Pests and Diseases. in his published work was to overcome the acids, producing ATP [e.g. Pierpoint, W.S. From studies of mechanisms of difficulty “of extracting such entities, unaltered (1959). Mitochondrial preparations from pathogenesis Stan developed an interest in and in their functional state, from the complex the leaves of tobacco (Nicotiana tabacum) salicylic acid (‘Aspirin’) and its role in regulating milieu of disintegrated, homogenized tissue Biochemical Journal 71, 518–528]. He was, metabolism in infected cells; after retirement and the specialized compartments within cells.” however, somewhat disappointed at not he published not only on its biochemistry, but Stan succeeded and was the first to isolate intact identifying the peroxisome. also on the history of its discovery and the mitochondria, capable of ATP synthesis. Significant advances were made on the discoverers and eventual exploitation. He had, Born in Stoke-on-Trent, the son of Ann effects on proteins of substances released it seems, fun with papers such as ‘Why should and William Pierpoint, Stan completed his during cell disruption, e.g. flavonoids and plants make medicine – don’t they do enough schooling at Morecambe Grammar School, phenolics and the products of their oxidation, for mankind already?’ [W.S. Pierpoint (2000) Lancashire, UK, a co-ed (perhaps a good including o-quinones. Stan showed that these The Biochemist 22(1), 37–40]. grounding for his social skills), in 1948. There reacted with the amino acids and thiols in Stan’s humour and writing are illustrated by a biology teacher, Mrs Pearsall, wife of a well- proteins, including potato virus X, forming this extract from a letter, “The reminder in the known ecologist, had considerable influence. characteristic coloured products [e.g. Pierpoint article by [author’s name] of the 100th birthday However, he studied chemistry for his BSc in W.S. (1969) o-Quinones formed in plant of the Aspirin must have provided celebratory Sheffield, UK, from 1948 to 1951, obtaining a extracts. Their reactions with amino acids and street parties all around the country; let’s hope first: it seems that he was fascinated early by the peptides. Biochemical Journal 112, 609–616], that the analgesic properties of the little white atomic/molecular scale and mechanisms. Then reactions still important in food processing pills coped adequately with any consequential followed a grant from the Medical Research and storage. This expertise resulted in reviews hangovers”. Then, after an analysis of more 56 February 2014 © Biochemical Society Obituary technical points about the synthesis of aspirin Stone for the Royal Society. His later writings Stan was a man of great integrity: in science by plants, he concludes: “But if plants don’t continued to be more historical, including a he pursued his interests, which were focused but make Aspirin itself, they could be persuaded study of a doctor, Henry Stephens, inventor of not narrow, to the great benefit of the subject to do so, as fortuitous juxtaposition of this high-grade ink, from Redbourn where Stan and and to the intellectual life of Rothamsted, with article with one on Genetic Engineering might Maureen lived. A book entitled The Unparallel rigour, persistence and eloquence. He was suggest. The thought of seeing fields of Aspirin- Lives of Three Medical Students: John Keats unfailingly courteous, helpful and positive containing potato plants scattered across the (1795–1821), Henry Stephens (1796–1864) towards PhD students, not only his own, Home Counties might give people headaches, and George Wilson Mackereth (1793–1869): and to younger scientists as well as the more Downloaded from https://portlandpress.com/biochemist/article-pdf/36/1/56/6265/bio036010056.pdf by UK user on 25 November 2019 but at least, the remedy would be close at hand”. Pencraft, Poetry and Persistent Practice appeared established. He is survived by Maureen, whom Stan was awarded a DSc for his outstanding in 2010, and an article on Charles Severn, a he married in 1957, their children, Judith and work and research record in 1990, the year fellow medical student of Keats, in the Keats– Nicholas, and five grandchildren, to whom he of retirement. He continued reviewing the Shelley Review in September 2012. These gave was inspirational and caring. ■ literature related to cell metabolism and him a little pride and much pleasure as did his responses to pathogens. Also, Stan wrote life-long membership of the Labour Party and a David Lawlor an obituary of Pirie and a paper on Edward term as Parish Councillor in Redbourn. (Rothamsted Research, UK) On the passing of Fred Sanger, Michael Neuberger and Sir John Cornforth The Biochemical Society is saddened to notebooks (1944–1981) to the Society Oxford University in 1941. After the war, he learn of the passing of Fred Sanger, Michael providing an important snapshot in the moved to the Medical Research Council’s Neuberger and Sir John Cornforth, three history of science and a record of experiments National Institute for Medical Research in internationally renowned biochemists whose leading to his award-winning work. London where, with George Popják, he went work inspired and continues to inspire Michael Neuberger’s elegant research on to devise a complete carbon-by-carbon researchers throughout the world. into antibodies did much to increase our degradation of the 19-carbon ring structure A brilliant biochemist and a modest man understanding of how the body defends of cholesterol and to identify, by means of whose passion lay in laboratory life, Fred itself against microbes. He was awarded radioactive tracers, the arrangement of the Sanger was awarded two Nobel Prizes in the Novartis Medal by the Society in 2002. acetate groups from which the system is built. Chemistry and was only the fourth person Michael Neuberger was a Fellow of Trinity Alongside Vladimir Prelog, John Cornforth ever to be so honoured.
Load more

Recommended publications
  • RSC Branding
    Royal Society of Chemistry National Chemical Landmarks Award Honouree Location Inscription Date The Institute of Cancer Research, Chester ICR scientists on this site and elsewhere pioneered numerous new cancer drugs from 10 Institute of Cancer Beatty Laboratories, 237 the 1950s until the present day – including the discovery of chemotherapy drug December Research Fulham Road, Chelsea carboplatin, prostate cancer drug abiraterone and the genetic targeting of olaparib for 2018 Road, London, SW3 ovarian and breast cancer. 6JB, UK The Institute of Cancer ICR scientists on this site and elsewhere pioneered numerous new cancer drugs from 10 Research, Royal Institute of Cancer the 1950s until the present day – including the discovery of chemotherapy drug December Marsden Hospital, 15 Research carboplatin, prostate cancer drug abiraterone and the genetic targeting of olaparib for 2018 Cotswold Road, Sutton, ovarian and breast cancer. London, SM2 5NG, UK Ape and Apple, 28-30 John Dalton Street was opened in 1846 by Manchester Corporation in honour of 26 October John Dalton Street, famous chemist, John Dalton, who in Manchester in 1803 developed the Atomic John Dalton 2016 Manchester, M2 6HQ, Theory which became the foundation of modern chemistry. President of Manchester UK Literary and Philosophical Society 1816-1844. Chemical structure of Near this site in 1903, James Colquhoun Irvine, Thomas Purdie and their team found 30 College Gate, North simple sugars, James a way to understand the chemical structure of simple sugars like glucose and lactose. September Street, St Andrews, Fife, Colquhoun Irvine and Over the next 18 years this allowed them to lay the foundations of modern 2016 KY16 9AJ, UK Thomas Purdie carbohydrate chemistry, with implications for medicine, nutrition and biochemistry.
    [Show full text]
  • Robert Burns Woodward
    The Life and Achievements of Robert Burns Woodward Long Literature Seminar July 13, 2009 Erika A. Crane “The structure known, but not yet accessible by synthesis, is to the chemist what the unclimbed mountain, the uncharted sea, the untilled field, the unreached planet, are to other men. The achievement of the objective in itself cannot but thrill all chemists, who even before they know the details of the journey can apprehend from their own experience the joys and elations, the disappointments and false hopes, the obstacles overcome, the frustrations subdued, which they experienced who traversed a road to the goal. The unique challenge which chemical synthesis provides for the creative imagination and the skilled hand ensures that it will endure as long as men write books, paint pictures, and fashion things which are beautiful, or practical, or both.” “Art and Science in the Synthesis of Organic Compounds: Retrospect and Prospect,” in Pointers and Pathways in Research (Bombay:CIBA of India, 1963). Robert Burns Woodward • Graduated from MIT with his Ph.D. in chemistry at the age of 20 Woodward taught by example and captivated • A tenured professor at Harvard by the age of 29 the young... “Woodward largely taught principles and values. He showed us by • Published 196 papers before his death at age example and precept that if anything is worth 62 doing, it should be done intelligently, intensely • Received 24 honorary degrees and passionately.” • Received 26 medals & awards including the -Daniel Kemp National Medal of Science in 1964, the Nobel Prize in 1965, and he was one of the first recipients of the Arthur C.
    [Show full text]
  • St Catherine's College Oxford
    MESSAGES The Year St Catherine’s College . Oxford 2013 ST CATHERINE’S COLLEGE 2013/75 MESSAGES Master and Fellows 2013 MASTER Susan C Cooper, MA (BA Richard M Berry, MA, DPhil Bart B van Es (BA, MPhil, Angela B Brueggemann, Gordon Gancz, BM BCh, MA Collby Maine, PhD California) Tutor in Physics PhD Camb) DPhil (BSc St Olaf, MSc Fellow by Special Election Professor Roger W Professor of Experimental Reader in Condensed Tutor in English Iowa) College Doctor Ainsworth, MA, DPhil, Physics Matter Physics Senior Tutor Fellow by Special Election in FRAeS Biological Sciences Geneviève A D M Peter R Franklin, MA (BA, Ashok I Handa, MA (MB BS Tommaso Pizzari, MA (BSc Wellcome Trust Career Helleringer (Maîtrise FELLOWS DPhil York) Lond), FRCS Aberd, PhD Shef) Development Fellow ESSEC, JD Columbia, Maîtrise Tutor in Music Fellow by Special Election in Tutor in Zoology Sciences Po, Maîtrise, Richard J Parish, MA, DPhil Professor of Music Medicine James E Thomson, MChem, Doctorat Paris-I Panthéon- (BA Newc) Reader in Surgery Byron W Byrne, MA, DPhil DPhil Sorbonne, Maîtrise Paris-II Tutor in French John Charles Smith, MA Tutor for Graduates (BCom, BEng Western Fellow by Special Election in Panthéon-Assas) Philip Spencer Fellow Tutor in French Linguistics Australia) Chemistry Fellow by Special Election Professor of French President of the Senior James L Bennett, MA (BA Tutor in Engineering Science in Law (Leave H14) Common Room Reading) Tutor for Admissions Andrew J Bunker, MA, DPhil Leverhulme Trust Early Fellow by Special Election Tutor in Physics
    [Show full text]
  • John Keats 1 John Keats
    John Keats 1 John Keats John Keats Portrait of John Keats by William Hilton. National Portrait Gallery, London Born 31 October 1795 Moorgate, London, England Died 23 February 1821 (aged 25) Rome, Italy Occupation Poet Alma mater King's College London Literary movement Romanticism John Keats (/ˈkiːts/; 31 October 1795 – 23 February 1821) was an English Romantic poet. He was one of the main figures of the second generation of Romantic poets along with Lord Byron and Percy Bysshe Shelley, despite his work only having been in publication for four years before his death.[1] Although his poems were not generally well received by critics during his life, his reputation grew after his death, so that by the end of the 19th century he had become one of the most beloved of all English poets. He had a significant influence on a diverse range of poets and writers. Jorge Luis Borges stated that his first encounter with Keats was the most significant literary experience of his life.[2] The poetry of Keats is characterised by sensual imagery, most notably in the series of odes. Today his poems and letters are some of the most popular and most analysed in English literature. Biography Early life John Keats was born in Moorgate, London, on 31 October 1795, to Thomas and Frances Jennings Keats. There is no clear evidence of his exact birthplace.[3] Although Keats and his family seem to have marked his birthday on 29 October, baptism records give the date as the 31st.[4] He was the eldest of four surviving children; his younger siblings were George (1797–1841), Thomas (1799–1818), and Frances Mary "Fanny" (1803–1889) who eventually married Spanish author Valentín Llanos Gutiérrez.[5] Another son was lost in infancy.
    [Show full text]
  • Sir John Warcup Cornforth
    Sir John Warcup Cornforth The degree of Doctor of Science (honoris causa) was conferred upon Sir John Warcup Cornforth at a ceremony held in the Great Hall on 2 November 1977. Sir John Warcup Cornforth, photo G3_224_1122, University of Sydney Archives. Citation A Nobel Prize-winning chemist who has been totally deaf for the past 40 years will be awarded the honorary degree of Doctor of Science by the University at a cemony in the Great Hall next Wednesday, November 2, 1977. He is Sir John Cornforth, 60, who was awarded the Nobel Prize for Chemistry in 1975 for his work on the stereochemistry of enzyme-catalysed reactions. He is currently the Royal Society Research Professor at the University of Sussex, and during his four-week visit to Australia he will deliver lectures in Sydney, Canberra, Melbourne and Adelaide. Sir John entered this University at the age of 16. The first signs of his deafness (from otosclerosis) had begun when he was 10, and although he had been able to profit from teaching at Sydney Boys' School, he was unable to hear any lecture at the University. He was, however, attracted by laboratory work in organic chemistry (which he had done in an improvised laboratory at home since the age of 14) and by the availability of original chemical literature. In 1937 he graduated with first-class honours and the University medal. After a year of postgraduate research he won a scholarship to work at Oxford. Two such scholarships were awarded each year, and the other was won by Rita Harradence, also of Sydney and also a winner of the University medal.
    [Show full text]
  • Robert Burns Woodward 1917–1979
    NATIONAL ACADEMY OF SCIENCES ROBERT BURNS WOODWARD 1917–1979 A Biographical Memoir by ELKAN BLOUT Any opinions expressed in this memoir are those of the author and do not necessarily reflect the views of the National Academy of Sciences. Biographical Memoirs, VOLUME 80 PUBLISHED 2001 BY THE NATIONAL ACADEMY PRESS WASHINGTON, D.C. ROBERT BURNS WOODWARD April 10, 1917–July 8, 1979 BY ELKAN BLOUT OBERT BURNS WOODWARD was the preeminent organic chemist Rof the twentieth century. This opinion is shared by his colleagues, students, and by other distinguished chemists. Bob Woodward was born in Boston, Massachusetts, and was an only child. His father died when Bob was less than two years old, and his mother had to work hard to support her son. His early education was in the Quincy, Massachusetts, public schools. During this period he was allowed to skip three years, thus enabling him to finish grammar and high schools in nine years. In 1933 at the age of 16, Bob Woodward enrolled in the Massachusetts Institute of Technology to study chemistry, although he also had interests at that time in mathematics, literature, and architecture. His unusual talents were soon apparent to the MIT faculty, and his needs for individual study and intensive effort were met and encouraged. Bob did not disappoint his MIT teachers. He received his B.S. degree in 1936 and completed his doctorate in the spring of 1937, at which time he was only 20 years of age. Immediately following his graduation Bob taught summer school at the University of Illinois, but then returned to Harvard’s Department of Chemistry to start a productive period with an assistantship under Professor E.
    [Show full text]
  • Historical Group
    Historical Group NEWSLETTER and SUMMARY OF PAPERS No. 67 Winter 2015 Registered Charity No. 207890 COMMITTEE Chairman: Dr J A Hudson ! Dr C Ceci (RSC) Graythwaite, Loweswater, Cockermouth, ! Dr N G Coley (Open University) Cumbria, CA13 0SU ! Dr C J Cooksey (Watford, Hertfordshire) [e-mail [email protected]] ! Prof A T Dronsfield (Swanwick, Secretary: Prof. J. W. Nicholson ! Derbyshire) 52 Buckingham Road, Hampton, Middlesex, ! Prof E Homburg (University of TW12 3JG [e-mail: [email protected]] ! Maastricht) Membership Prof W P Griffith ! Prof F James (Royal Institution) Secretary: Department of Chemistry, Imperial College, ! Dr M Jewess (Harwell, Oxon) London, SW7 2AZ [e-mail [email protected]] ! Dr D Leaback (Biolink Technology) Treasurer: Dr P J T Morris ! Mr P N Reed (Steensbridge, Science Museum, Exhibition Road, South ! Herefordshire) Kensington, London, SW7 2DD ! Dr V Quirke (Oxford Brookes University) [e-mail: [email protected]] !Prof. H. Rzepa (Imperial College) Newsletter Dr A Simmons !Dr A Sella (University College) Editor Epsom Lodge, La Grande Route de St Jean, St John, Jersey, JE3 4FL [e-mail [email protected]] Newsletter Dr G P Moss Production: School of Biological and Chemical Sciences, Queen Mary University of London, Mile End Road, London E1 4NS [e-mail [email protected]] http://www.chem.qmul.ac.uk/rschg/ http://www.rsc.org/membership/networking/interestgroups/historical/index.asp 1 RSC Historical Group Newsletter No. 67 Winter 2015 Contents From the Editor 2 ROYAL SOCIETY OF CHEMISTRY HISTORICAL GROUP NEWS The Life and Work of Sir John Cornforth CBE AC FRS 3 Royal Society of Chemistry News 4 Feedback from the Summer 2014 Newsletter – Alwyn Davies 4 Another Object to Identify – John Nicholson 4 Published Histories of Chemistry Departments in Britain and Ireland – Bill Griffith 5 SOCIETY NEWS News from the Historical Division of the German Chemical Society – W.H.
    [Show full text]
  • Sir James Fraser Stoddart Baran Lab GM 2010-08-14
    Y. Ishihara Sir James Fraser Stoddart Baran Lab GM 2010-08-14 (The UCLA USJ, 2007, 20, 1–7.) 1 Y. Ishihara Sir James Fraser Stoddart Baran Lab GM 2010-08-14 (The UCLA USJ, 2007, 20, 1–7.) 2 Y. Ishihara Sir James Fraser Stoddart Baran Lab GM 2010-08-14 Professor Stoddart's publication list (also see his website for a 46-page publication list): - 9 textbooks and monographs - 13 patents "Chemistry is for people - 894 communications, papers and reviews (excluding book chapters, conference who like playing with Lego abstracts and work done before his independent career, the tally is about 770) and solving 3D puzzles […] - At age 68, he is still very active – 22 papers published in the year 2010, 8 months in! Work is just like playing - He has many publications in so many fields... with toys." - Journals with 10+ papers: JACS 75 Acta Crystallogr Sect C 26 ACIEE 67 JCSPT1 23 "There is a lot of room for ChemEurJ 62 EurJOC 19 creativity to be expressed JCSCC 51 ChemComm 15 in chemis try by someone TetLett 42 Carbohydr Res 12 who is bent on wanting to OrgLett 35 Pure and Appl Chem 11 be inventive and make JOC 28 discoveries." - High-profile general science journals: Nature 4 Science 5 PNAS 8 - Reviews: AccChemRes 8 ChemRev 4 ChemSocRev 6 - Uncommon venues of publication for British or American scientists: Coll. Czechoslovak Chem. Comm. 5 Mendeleev Communications 2 Israel Journal of Chemistry 5 Recueil des Trav. Chim. des Pays-Bas 2 Canadian Journal of Chemistry 4 Actualité chimique 1 Bibliography (also see his website, http://stoddart.northwestern.edu/ , for a 56-page CV): Chemistry – An Asian Journal 3 Bulletin of the Chem.
    [Show full text]
  • Information to Users
    INFORMATION TO USERS This manuscript has been reproduced from the microfilm master. UMI films the text directly from the original or copy submitted. Thus, some thesis and dissertation copies are in typewriter face, while others may be from any type of computer printer. The quality of this reproduction is dependent upon the quality of the copy subm itted. Broken or indistinct print, colored or poor quality illustrations and photographs, print bleedthrough, substandard margins, and improper alignment can adversely affect reproduction. In the unlikely event that the author did not send UMI a complete manuscript and there are missing pages, these will be noted. Also, if unauthorized copyright material had to be removed, a note will indicate the deletion. Oversize materials (e.g., maps, drawings, charts) are reproduced by sectioning the original, beginning at the upper left-hand comer and continuing from left to right in equal sections with small overlaps. Photographs included in the original manuscript have been reproduced xerographically in this copy. Higher quality 6* x 9" black and white photographic prints are available for any photographs or illustrations appearing in this copy for an additional charge. Contact UMI directly to order. ProQuest Information and Learning 300 North Zeeb Road, Ann Arbor, Ml 48106-1346 USA 800-521-0600 Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. NOTE TO USERS This reproduction is the best copy available. UMI Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. Reproduced with permission of the copyright owner.
    [Show full text]
  • Leading Research for Better Health
    < Contents > Contents Please click on the > to go directly to the page. > Introducing the MRC >AchievementsIntroducing thetimeline MRC Achievements>1913 to 1940s timeline >1950s to 1980s >1913 to 1940s >1990s to 2006 >1950s to 1980s >1990s to 2006 > Leading research for better health >NobelLeading Prize resear timelinech for better health Nobel>1929 Prizeto 1952 timeline >1953 to 1962 >1929 to 1952 >1972 to 1984 >1953 to 1962 >1997 to 2003 >1972 to 1984 1997 to 2003 >MRC research over the decades MRC> From resear discochvery over to healthcare:the decades translational research > EvidenceFrom discovery for best to pr healthcareactice: clinical — translational trials research > EvidencePublic health for bestresearch practice: clinical trials > PubDNAlic revhealtholution research > ReducingDNA rev olutionsmoking: preventing deaths > ReducingTherapeutic smoking: antibodiespreventing deaths > TherapeuticReducing deaths antibodies from infections in Africa > ReducingPreventing deaths heart fromdisease infections in Africa > PrevMedicalenting imaging: hearttransformingdisease diagnosis > MedicalCutting childimaging: leukaemia transforming deaths diagnosis > Cutting child leukaemia deaths < Click on any link to go< directly Contentsto a page >> < Contents > < Contents > < Contents > < Contents > Leading research for better health The most important part of the MRC’s mission trials, such as those on the use of statins to lower is to encourage and support high-quality research cholesterol and on vaccines in Africa.The MRC with the aim of improving human health.The MRC is the UK’s largest public funder of clinical trials is committed to supporting research across the and it supports some of the most productive entire spectrum of the biomedical and clinical and ambitious epidemiological studies in the world, sciences. We are proud of our international including the UK Biobank.
    [Show full text]
  • Sir John and Lady Rita Cornforth: a Distinguished Chemical Partnership
    Sir John and Lady Rita Cornforth: a distinguished chemical partnership Article (Accepted Version) Purchase, Rupert and Hanson, James (2015) Sir John and Lady Rita Cornforth: a distinguished chemical partnership. Science Progress, 98 (3). 212-218(7). ISSN 0036-8504 This version is available from Sussex Research Online: http://sro.sussex.ac.uk/id/eprint/71956/ This document is made available in accordance with publisher policies and may differ from the published version or from the version of record. If you wish to cite this item you are advised to consult the publisher’s version. Please see the URL above for details on accessing the published version. Copyright and reuse: Sussex Research Online is a digital repository of the research output of the University. Copyright and all moral rights to the version of the paper presented here belong to the individual author(s) and/or other copyright owners. To the extent reasonable and practicable, the material made available in SRO has been checked for eligibility before being made available. Copies of full text items generally can be reproduced, displayed or performed and given to third parties in any format or medium for personal research or study, educational, or not-for-profit purposes without prior permission or charge, provided that the authors, title and full bibliographic details are credited, a hyperlink and/or URL is given for the original metadata page and the content is not changed in any way. http://sro.sussex.ac.uk Doi: 10.3184/003685015X14364530625058 Sir John and Lady Rita Cornforth: a distinguished chemical partnership RUPERT PURCHASE and JAMES R.
    [Show full text]
  • Trades' Directory, 1882. Pub
    1801 TRADES' DIRECTORY, 1882. PUB Cr01b11 &: Leelr:, Thomas Hyams, Deal street, Drayton, Alfred Kay, 89 Thistle grove SW Duke of SussPx, Frcderick Henry West, 10&- Mile end New town E Dreghorn Castle, George Abseil, 157 Queen's Islington High streef N Cr0111n &: Sceptre, Edward Betambeau, 30 crescent, Haverstock hill NW Duke of Sutherland, John Stride Ripley,. Britannia street, Citv road N Druid's Arm.•, Mrs. Mary Bending, 34 East 51 Lorrimore road, Walworth SE -John Chambers. ~4 Boiland rd.Knsngton W street, ManchPster square W Duke of Wellington. Henry Thomas Back~ - Wm.Chandler,47Edward st.Hampstd.rdNW Druid'siiead.Wm.Wood, 8 Chrch.st.DptfrdS E 2~2 Shoreditch High street E -Andrew Jcfferys, 57 Shad Thames SE Drum, Edmd .. Thn. Carpenter,l6Snow's fldsS E - William Bevan, V.rellington st.DeptfordS E' - Edwd.Knightley, :!4 Ware st. Kingslr.d.rd N !. DrummondHtl.Fdk.Taplin,li4 Drummnd.stNW - JohnBrisley,45Wcllngtn.st.Nw.KentrdS E- - Ebem~zer S. MP.rP.dith, 22 Old Change E C I Dublin Castle, George Crescence Taylor, 18 -John Carpenter, 119 Ball's Pond road N -Mrs. Isabella Sarah Ravenscroft (exors. of), Park street, Camden t{)wn NW -Wm. Child&, 1 Repton st. Limeho. fields E 94 Sceptre st. West st. Mile end Old twn E : Duche.u of Clarence, Robert Franci• L. -Richd. Clt~.rke,29 ThreeColt la.Cambdg.rd E' -Henry Thos. Schwarz, 26 & 27 Foley st W i Baughan, 171 Vauxhall bridge road SW - Wm.EleazerClarke, 8Wellingi;n. st.PntnvlN -Wm. Treadwell, lB2 Brompton road SW 1 Ducltes.• of Edinb1~rgh, .John Birks, 115 Great -John R.
    [Show full text]