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Discoveries 2017 Discoveries 2017 University of Washington Orthopaedics & Sports Medicine University of Washington Department of Orthopaedics and Sports Medicine Discoveries 2017 Department of Orthopaedics and Sports Medicine University of Washington Seattle, WA 98195 EDITOR-IN-CHIEF: Howard A. Chansky, MD [email protected] ASSISTANT EDITORS: Christopher H. Allan, MD [email protected] Stephen A. Kennedy, MD [email protected] Adam A. Sassoon, MD, MS [email protected] MANAGING EDITOR: Fred Westerberg [email protected] Front Cover Illustration: “Bridge near Perfection Lake, The Enchantments, Central Cascades, WA” photograph by Nicholas Iannuzzi, MD A pdf of this publication is available at our website: www.orthop.washington.edu. Permission Requests: All inquiries should be directed to the Managing Editor, University of Washington, Department of Orthopaedics and Sports Medicine, 1959 NE Pacific Street, Box 356500, Seattle, WA 98195-6500, or at the email address above. Contents 1 Foreword 2 From The Assistant Editors: The Winding Path Toward Perfection Lake 3 2017 Distinguished Alumnus, Sigvard T. Hansen, Jr., MD 4 Ernest U. Conrad III, MD 5 New Faculty 7 Department of Orthopaedics and Sports Medicine Faculty 13 Visiting Lecturers Non-Modular Tapered Fluted Stems 15 Ryan Stancil, MD, Nathan Summers, PA-C, in Complex Primary Total Hip Arthroplasty and Adam Sassoon, MD, MS Requiring Concurrent Osteotomy Semiconstrained Total Distal Radioulnar 18 Mary Kate Thayer, MD, Kate Bellevue, MD, Joint Prosthesis for Distal Radioulnar Mike Pouliot, MD, Jerry I. Huang, MD, Joint Arthrosis and Douglas P. Hanel, MD Proline 3-Hydroxylation of Type II Collagen 22 David M. Hudson, PhD, Marilyn Archer, BS, Synthesized by a Rat Cell Line MaryAnn Weis, BS, David R. Eyre, PhD, Suggests a Nucleus Pulposus Origin and Russell J. Fernandes, PhD Psychometric Properties of the Simple Shoulder 24 Jason E. Hsu, MD, Stacy M. Russ, BA, Test in Over 400 Patients Jeremy S. Somerson, MD, Anna Tang, BS, Undergoing Shoulder Arthroplasty Winston J. Warme, MD, and Frederick A. Matsen III, MD Metatarsal Shape and Foot Type: 26 Scott Telfer, EngD, Matthew W. Kindig, MS, A Geometric Morphometric Analysis Bruce J. Sangeorzan, MD, and William R. Ledoux II, PhD P3h3-null and Sc65-null Mice Phenocopy the 28 David M. Hudson, PhD, MaryAnn Weis, BS, Collagen Lysine Under-Hydroxylation and Cross- Jyoti Rai, MS, Kyu Sang Joeng, Linking Abnormality of Ehlers-Danlos Syndrome Brendan H. Lee, Roy Morello, Type VIA and David R. Eyre, PhD Evaluation of Appropriate Venous 30 Christopher M. Domes, MD, Thromboembolism Prophylaxis in Orthopaedic Anneliese M. Schleyer, MD, Trauma Patients with Symptom-Driven Vascular James M. McQueen, BS, and Radiographic Studies Ronald F. Pergamit, MPA, and Daphne M. Beingessner, MD Rapid-Throughput Skeletal Phenomics in Zebrafish 32 Matthew Hur, Charlotte A. Gistelinck, Philippe Huber, BS, Jane Lee, Marjorie H. Thompson, Adrian T. Monstad-Rios, Claire J. Watson, PhD, Sarah K. McMenamin, PhD, Andy Willaert, PhD, David M. Parichy, PhD, Paul Coucke, PhD, and Ronald Y. Kwon, PhD Static Preloading: A Previously 33 Sundar Srinivasan, PhD, D. Balsiger, Unrecognized Inhibitor of Bone Anabolism Phillipe Huber, BS, Steven D. Bain, PhD, Edith M. Gardiner, PhD, and Ted S. Gross, PhD Excessive Clavicular Resection Treated with 35 Winston J. Warme, MD, Jeremy S. Somerson, MD, Clavicular Lengthening, Sternoclavicular and and Galen Mills, MS3 Acromioclavicular Joint Stabilization – Case Report Comprehensive Assessment of Outcomes from 39 Kushagra Verma, MD, Oheneba Boachie-Adjei, Patients with Severe Early Onset Spine Deformity Theresa Yirerong, Harry Akoto, Treated with A Vertebral Column Resection: and Irene Wulff Results from An SRS Global Outreach Site (FOCOS) in Ghana Preoperative Opioid Use Is Associated with 40 Howard A. Chansky, MD Early Revision After Total Knee Arthroplasty 42 Harborview Medical Center Orthopaedics 44 Seattle Children’s Hospital Orthopaedics 47 University of Washington Medical Center and Northwest Hospital Orthopaedics 49 VA Puget Sound Orthopaedics 50 Graduating Residents 52 Incoming Residents 54 ACEs and Fellows 56 Research Grants 58 Department Publications 2016-2017 66 Alumni 69 Endowments Foreword t is my privilege to serve as the Chair of the Department of Orthopaedics and Sports Medicine in a time of continued challenges and change in the practice and business of medicine. Our common pursuit of the best possible care for our patients, formalized in name as “The Triple Aim” by the Institute of Healthcare Improvement, is the mission that serves Ito unite the entire Department. The Triple Aim refers to improving the care of individual patients, improving the health of populations and reducing the cost of healthcare. Our faculty and staff demonstrate their commitment to these goals of the Triple Aim in myriad ways via development of clinical pathways to enhance safe and cost-effective care, teaching surgical skills to colleagues from around the world as well as our residents and fellows, and basic and clinical research to define and improve orthopaedic outcomes. Contributions to the Triple Aim do not always directly involve activity in the laboratory or the hospital. It is accepted wisdom, confirmed by research, that diversity and inclusiveness in training programs makes for better doctors. Better doctors makes for better patient care, and diversity in the orthopaedic workforce is one element in addressing persistent disparities in musculoskeletal heath and access to healthcare. While we all realize this is a long-term effort, under the guidance of Angela Weiss, Doug Hanel and Lisa Taitsman we have made recent strides in attracting very talented underrepresented minorities to our residency program. In addition, we have made early progress in diversifying our faculty. We hope to capitalize on this early success with further focused efforts to promote inclusivity and diversity throughout our Department. In this latest issue of Discoveries we highlight annual faculty and programmatic developments at the University of Washington Medical Center, Seattle Children’s Hospital, the Puget Sound VA Healthcare System, Northwest Hospital and Harborview Medical Center. However, the main focus of Discoveries remains the clinical and basic research performed by our trainees and faculty, each of our laboratories and clinical campuses. The managing editor Fred Westerberg as well as co-editors Drs. Chris Allan, Stephen Kennedy and Adam Sassoon have once again produced an excellent annual summary of the Department of Orthopaedics and Sports Medicine. Thank you for your interest in this issue and please do not hesitate to contact Fred or myself with questions or ideas for future issues. Howard A. Chansky, MD Professor and Chair DISCOVERIES 2017 1 From The Assistant Editors: The Winding Path Toward Perfection Lake e would first like to express Undergoing Shoulder Arthroplasty” our gratitude for the invitation further validates this brief and simple from Dr. Chansky to return instrument for assessing the outcomes Was assistant editors for Discoveries of shoulder arthroplasty. 2017. We were honored to be involved Our articles also represent the with the process, and enjoyed reading important role our Department plays and participating again in the variety of in the tertiary care of patients requiring articles representing the ongoing work complex joint arthroplasty or multiple in the UW Department of Orthopaedics system injuries. Dr. Sassoon reports and Sports Medicine. his early outcomes in the use of This year’s cover photo was taken nonmodular stems for complex primary by Nicholas Iannuzzi MD, while hiking hip arthroplasty. Dr. Thayer et al share here in Washington State, in the the University of Washington experience Enchantments basin of the Central on the reconstruction of distal radioulnar Cascades. A small footbridge leads joint arthrosis using a semiconstrained to a winding path around Perfection total DRUJ prosthesis. Dr. Domes Lake. Trees decorate the landscape in et al report on the appropriate VTE different stages of growth and a variety prophlaxis in orthopaedic trauma of curves and shapes, reminiscent patients. of our departmental emblem of the We hope you enjoy reading this Space Needle guiding the growth of a year’s edition of Discoveries and that Douglas Fir. Dr. Iannuzzi commented you find the articles as stimulating as on the photo “Believe it or not, that’s we did. the name of the lake. Not much of an understatement there.” Adam Sassoon, MD, MS As orthopaedists and sports Christopher Allan, MD medicine specialists, we so often Stephen Kennedy, MD seek “perfection” for our patients. As scientists, we believe in a method of investigation that consists of systematic observation, measurement, and experiment, and the formulation of questions and testing of hypotheses. This journey can be winding, and sometimes uphill, but persistence, keen observation, and serendipity can allow for discovery and a footbridge toward our goal. Our basic science articles in this edition include studies that make use of animal models such as zebrafish or mice, or cell culture lines, combined with advanced molecular techniques and a variety of measurements, to better understand the genetics and molecular building blocks that can influence growth, joint function, and deformity. Our clinical outcome studies reflect continued use and development of patient reported outcome instruments. Dr. Matsen first reported the Simple Shoulder Test (SST) in 1995 as a self-assessment of shoulder function in glenohumeral
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