f\lE CO?~ ecor U . 5 . DEPARTMENT OF October 23, 1974 NATIONAL INSTITUTES OF HEALTH H EALTH . EDUCATION, AND W ELFARE Vol. XXVI, No. 22 2 NIH Grantees Share Dr. DeVita to Head NCI Dr. Gajdusek to Talk on Studies of Kuru, Nobel Prize in Medicine Cancer Treatment Div. New Guinean Disease, at Dyer Lecture By Carolyn Holstein With Another Scientist A rare insight into the mysterious workings of insidious slow viruses Two NlH grantees-Dr. George which persist in -the body months or years before fatally striking the Emil Palade and Dr. Christian de central nervous system will be offered by the National Institute of Duve-shared the Nobel Prize for Neuroioiical Diseases and Stroke Medicine or Physiology with an scientist who first demonstrated American scientist, Dr. Albert their existence-Dr. D. Carleton Claude, who heads the Institute Gajdusek. Jules Bordet in Brussels. Dr. Gajdusek, who was elected The award was announced by to membership in t he National the Royal Karolinska Institute in Academy of Sciences this year, Sweden. On Dec. 10, the scientists will deliver the 24th Annual R. E. will receive the joint Nobel Prize Dyer Lecture in the Masur Audi at ceremonies in Stockholm. torium on Wednesday, Nov. 6, at The three laureates were cited 8:15 p.m. for being "largely r,esponsible for Dr. DeVito, who hos received seve ral He will discuss his research to t he creation of modern cell biolo find the cause of kuru, the first honors including the Lasker Medico I gy" and for 'their discoveries con chronic degenerative disease of cerning the structural and func Research Award, hos frequently been man proved to be a slow virus tional organization of the cell." cited for his accomplishments in the infection. Dr. Palade i-s a grantee of botJh therapy of Hodgkin's disease. Its discovery has attracted the National Institute of General worldwide attention and stimu Medical Sciences and the National Dr. Vincent T. DeVita, J r., has been appointed iocting director of lated the search for additional in Heart and Lung Institute. fections which may possibly cause Dr. Gojdusek, who began his research Lhe Division of Cancer Treatment, on the fotol nerve disease in 19S6, NIGMS Supports Center National Cancer Institute. other subacute and chronic CNS diseases. was recently elected to membership in He heads the NIGMS-supported Dr. DeVita succeeds Dr. C. Gor the Notional Academy of Sciences. Molecular Pathology Center at Y,ale don Zubrod, who recently retired Stuci,ed in Mountainous Interior University. Part of that grant will to assume the post of Director of Dr. Gajdusek, chief of the year after its onset. be used for Dr. P alade's research the newly created Comprehensive Labo:ratory of Central Nervous The cause of kuru stumped the on membrane interactions in eu Cancer Center at the University System Studies, began studying chemists for many reasons: it did karyo-tic cells. of Miami, Florida. kuru in the mountainous interior not a ppear to be contagious; it The NH.LI grant is supporting a Dr. DeVita has been chief of the of New Guinea in 19-56. Since then, rarely occurred in men, usually study at Yale University on the NCI Medicine Branch since 1971. about 2,500 cases of kuru have only in women and children, and localization of pore systems in ca Previously, he served in the In been recorded out of a total popu there was an absence of all known pillary walls. Dr. Palade is the stitute's Solid Tumor Ser vice from lation of 35,000. char-acteristics of infectious di principal investi•gator. 1966 to 1968 as senior investiga Kuru, which means "shivering" sease. Dr. de Duve, a National Institute tor, and from 1968 to 1971 as head in the New Guinean Fore lan (See DR. GAJDUSTJJK, Pago 4) (See NOBELTSTS, Page 5) (See DR. DEVITA, Page 7) guage, is characterized by cere bellar ataxia and shivering-like Office for Protection tremor. It progresses in three High Blood Pressure Screening Program stages to complete motor inca From Research Risks For All Employees Begins in November pacity and death within about a To Coordin.ate Policy The Office for Protection from NIH will begin a high blood pressure screening program next month 15-Minute Movie Will Tel! as a health service for all employees on campus or working in buildings Research Risks, headed by Dr. in the immediate area. About High Blood Pressure Donald Chalkley, will be establish The screening will be carried out by the National Heart and Lung An educational film about ed on Oct . 27 in the immediate Of lnstitute in cooperation with the the serious problem of high fice of the Director and Deputy Di National High Blood Pressure diagnose hypertension (a term blood pressure will be shown rectors, NIH. Education Program and lihe En1- used to descri·be high blood pres in the Masur Auditorium on Th OPRR takes over the princi ployee Health Service using volun sure). Oct. 29, Oct. 30, and Nov. 1 pal functions of the Institutional teer nurses from several area hos Employees with aibove normal during the lunch break. Relat ions Branch, Division of Re pitals. blood pressure will be encouraged What Goes Up, a 15-minute search Grants, which will be Studies have consistently shown to make an appointment with the film produced by the American abolished. that about one in every seven Employee Health Service for a Heart Association, will be The former DRG branch was ele adults has high blood pressure. further check. Those with consis shown a t 11:45 a.m. and 12:15 vated to the Office of the Director Only half of these people know tently high blood pressure will be p.m. because of its expanding responsi they have it, and only half of referred to their own doctor or See the film and have blood bilities and the importance of co those who know it receive ade clinic for further evaluation and pressure checked during the ordinating pro.grams designed. to quate treatment. treatment. NIH High Blood Pressure protect the welfare of human sub A single casual reading of blood No one other than the employee Screening Program. jects of biomedical and behavioral pressure is seldom sufficient to ( See BLOOD PRI!JSE;URFJ, Page 6) (See PROTFJCTTON, Page 6) Page 2 October 23, 1974 THE NIH RECORD Students Enroll in N·IH Clinical Electives Program ecord ' Published biweekly at Bethesda, Md., by the Publications and Repor ts Branch, Office of Infor mation, for the information of employees of the National Institutes of Health, Depar tment of Health, Educa tion, and Welfare, and circulated by request to interest ed writer s and to investi gators in t he field of biomedical and related research. The content is reprintable without !)er mission. Pictur es are available on request. The NIH Record reserves the right to make corrections, changes or dele tions in submitted copy in confor mity with the pol icies of t he paper and the Depar tment of Health, Education, and Welfare.
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Editor ...... Fronces W. Davis Dr. Philippe V. Cardon, Jr., (seated far left), CC associate director, explains the Associote Editor ...... Fay Levie ro program to the students who come from mony parts of the U.S. They will take port in clinical and research conferences, and receive training in one or more Staff Corresponde nts of five specialties including clinical psychophormacology, immunology, and ADA, J udy F leisher; CC, Thalia Roland; DCRT, Judith Jones; DRG, infectious diseases. Sue Meadows ; DRR, J erry Gordon; DRS, Cora M. Sult; FIC, George Presson; NCI, Carolann Hooton; NEI, Bonnie F riedman Spellane; NHLI, Seven women and twenty men selected from medical schools across Bill Sanders; NIAlD, Krin Kolsky ; NIAMDD, Pat Gorman ; NICHD, the country recently en rolled in the fall session of the NIH Clinical Kathy Kowalczyk; NIDR, Sue Hannon; NlEHS, EHzabeth Y. J a mes; Electives P rogram for Medical Students. NIGMS, Wanda Warddell; NI MH, Betty Zubovic; NINOS, Car olyn Hol The 9-week training course gives ------stein; NLM, Fran Patr ick. medical students an opportunity to ing with CC patien'ts and studying study a clinical su'bspecialty and their diseases. Administr·ative Servkes NIH Tennis Tournament Held gain firsthand experience in pa- Dr. Yecies mentioned the Na The finals of the NI H Tennis tient car e. The students will be tional Institute of Arthritis, Ho1ds Awards Cere·mony Club fall tournament were held working with collaborating investi- '.\1:etabolism, and Digestive Di The Division of Administrative Sunday afternoon, Sept. 22, at the gator,s from seven Institutes. seases' research on systemk lupus erythematosus. NIAMDD recruit- Services held its first annual Hon N IH tennis courts near Bldg. 41. In 1971, when the program was or Awards Ceremony in the l\'lasur Mort Stimler overcame a 5-2 first offered, Dr. Lewis Yecies, now ed SLE patients through referrals Auditorium on Oct. 7. deficit in the second set to defeat a clinical associate in the National from physicians all over the coun This program was the direct r e Adi Gazclar in straight sets for Inst itute of Allergy and Infectious try. the Men's Singles crown. Diseases, participated as a student The CC patients demonstrated sult of an EEO confe1·ence recom Mort and his partner, Ray Chen, while he was attending- the Uni- such a wide range of symptoms mendation that one day each year were less successful in Men's Dou versity of Pennsylvania Medical that it was possible to observe the be set aside to recognize those bles, however, losing in straight School. He spent 4 months at the entire spectrum of t he disease on DAS employees who had received sets to Will Carpenter and Rich Clinical Center training for work just one floor of the hospital. Dr. awards dur ing the previous year. Robinson in the finals. in cndocrinolo·gy and imrnunology. Yecies pointed out t hat this would More than 300 awards were pre Wendy Brody took the Women's be almost impossible at any other sented for employee suggestions, Singles championship with a vic Dr. Yecies said the course is• an inst itution. quality increases, cash and group tory over Ann Fatham. Wendy educational opportunity for medi cal students. He described the pro awar ds, superior performance, and her husband, Bill, defended Joyce Scherr Is Guest Speaker length-of-service, and EEO achieve their Mixed Doubles crown, over gram as non-pedantic with a flex At October M eeting of F.E.W . ments. coming Jeannine and Ed Scott in ible format. Leon Schwartz, NIH Associate a three-set match. He also lauded t he library facili J oyce Scherr, president of the Direetor for Administration, and Penny Brogan and Ann Fatham t ies here, the fact that the stu Parkla,wn Toastmist ress Club, will Raymond Jackson, N IH EEO Of were victorious in the ·w omen's dents receive instructions from be guest speaker at the October ficer, joined Otis Ducker, DAS Di Doubles final, defeating Fran Bau experts in specialized medical meeting o[ the Suburban Mary rector, in presenting the awards. er and Flora Feld. fieldJ, and the advantage of work- land chapter of F.E.W. (Federally Employed Women), to be held Wednesday, Oct. 30, at 12 noon in Conference Room A, Parklawn Bldg. Ms. Scherr will discuss How Toastmistress Training Helps Im prove Speaking a n r1 Leadership Skills. All federally employed women and their friends ar e invited.
American Artists to Perform In FAES Concert on Oct. 27 A group of young American ar tists, Jed by Peter Serkin, will pre sent a program ,,.,.hich will include selections by Mozart, Sti,avinsky, and Brahms next Sunday, Oct. 27, at 4 p.m., in the Masur Audi torium. FI RE PREVENTION WEEK AT NIH. From Oct. 7-1 T, thot 'Week wos observed with fire drills on the campus o nd othe: This is the second concert in the buildings housing NIH employees. In the afternoon of Oct. TO, employees in Bldg. 30 (1) pour out at the signal to evoc 1974-75 Chamber Music Series uate. One of the NIH fire trucks is stonding by. At the end of the fire drill in the Westwood Bldg., employees return to given by llhe Foundation for Ad their office. Not to worry a bout the lone straggler in the forefront who is wending her way back-she hod walked out of vanced Education in the Sciences. the building in quick-time. Admission is by ticket only. THE NIB RECORD October 23, 1974 Page 3 York Onnen Heads NHLI Dr. Arthur L. Schipper; Eve Larson Retires; NIH Reaches Halfway lnquirjes, Reports Bra,nch Her 'Temporary' Job Toward CFC Quota York E. Onnen has been ap Biologist at NCI, Dies Lasts for 17 Years The halfway mark in the Com pointed chief of the Public Inquir Dr. A1·thur L. Schipper, a biolo ies and Reports Branch within the bined Federal Campaign finds NIH gist at the National Cancer Insti just rubout halfway toward its National Heart and Lung Insti tute since 1959, died Oct. 11 of tute's Office of Prevention, Control, quota of $187,380. At press time cardio-res.piratory arrest. He had (last week) NIH had 1-ooched 48 and Education. suffered from cancer. That Branch 1>re.pares and dis perc~mt of its goal with $89,396 in seminates information about heart, Dr. Schipper was program direc contributions. blood vessel, lung, and blood dis tor for review activities in the This total included 2,415 contri eases and about NHLI programs Review and Referral Branch, Divi butions-an average gift of $37.02. for combatting these disorders. sion of Cancer Research Resources Two NIH u·nits have gone over Mr. Onnen comes to NIH from and Centers. t he top, more than 100 perce.nt of the Office of the Assistant Secre Previously, he had headed the their quotas. The Fogarty Inter tary for Public Affairs, HEW, Institute's graduate training pro national Genter reached 186 per where he served for 2 years as gram and later was executive sec cent of its quota wibh an average deputy director for Audiovisual retary of the Cancer Research contribution of almost $50 per Communications and represented Center Review Committee. person. the radio/TV media in the HEW Education Nated Meanwhile, the Division of Re press office. Dr. Schipper graduated from search Grants has scored 101 per Earlier, he had served for over Coe College in Cedar Rapids, and cent of its quota, giving almost received his master's degree and $40 per person. Not far behind is doctorate from the University of the National Library of Medicine, Iowa. which stands at 87 percent of its He was an associate professor Eve Larson's many friends ot NIAMDD quota, $37 per perso.n. of biology at Tuxas A & M Uni will miss he r sympathetic ear a 11d Next is the National Eye Insti versity from 1937 to 1948, except cheerful smile . tute. NEI now has reached 62 per for 2 years during World War II cent of its quota with $26 per when he served as an aviation Back in July 1957, Geneva "Eve" person. physiologist in the U.S. Army Air Larson came to work for the Na " We have done well so far, and Corps. tional lnstitute of Arbhri.tis, Me From 1948 to 1957 he was asso tabolism, and Digestive. Diseases ciate professor of biology at Notre with the idea of staying j ust long Dame Univer,sity. During part of enough to buy a new couch for this period he was also editor of her Rockville home. the , l111cril·<11~ Jlidland Nat'llralist. She stayed for 17 years, long Dr. Schipper served for 2 years enough to buy a lot of new couch at the Oak Ridge Institute of es. She also made many good Nuclear Studies befol'€ joining friends at NIH in spite of the NCI. fact that in her job as administra He is survived by his wife, Mil tive assistant she was frequently In the Air Force, Mr. Onnen produced dred, two sons, Arthur L., Jr., and required to say "no" or "this can't and directed an award-winning radio Ross E., a daughter, Mala A. be done this way." series. Schuster, and a brother, Johnnie. Aftet 20 years of Fedetal serv 3 years in the U.S. Air Force as The family suggests that ex ice, Mrs. Larson retired last a military aide in the White House, pressions of sympathy be sent month. and as Rad io/'I'V Officer for the through contributions to the Amer She started her Government ca AiT Force Systems Command. ican Cancer Society or the Patient reer in 1938 with the Federal De While he was wi~h the Air Welfare Fund at NIH. posit Insurance Corporation in At Force, he produced and directed lanta, Ga., as a temporary em One of many worthwhile organizations t h e radio series Oo1mtdo·1cti and ployee and remained until Decem benefitting from CFC is the Cerebral Cl-icmt Stell ; he was given the Silver ber 1941. Palsy Association of Montgomery Anvil Award for both programs. Mrs. Larson joined NIAMDD as County, Its workshop serves the area's Mr. Onnen received his B.A. de a clerk-stenographer, worked her handicapped adults and provides train gree in journalism from the Uni way up to administrative techni ing. A recent workshap graduate, Bob versity of Minnesota in 1965. As cian, and collected a thick person ette Montilla (I), hired by NIH as o an undergraduate, he worked with nel folder full of congratulatory Xerox machine operator in the CC, WOCO Television in Minneapolis. memoranda from her supervisors. hands some completed work to a co To show their gratitude for lis worke r Gerry Rice. EST Returns Next Sunday; tening to their stories of woe, the N lAMDD staff gave Mrs. Larson I am hopeful that with continued Set Clocks Back One Hour a portruble television set for her employee participation, we will A return to standard time kitchen. She also received an al reach our goal by the close of the for 4 months- from next Sun bum of pictures, nan-atives, and campaign on Nov. 8," said Dr. day, Oct. 27, to Sunday, Feb. drawings of fellow employees to Milo D. Leavi-t;t, FIC Direetor and 23, 1975-has been approved help her remember the staff. CFC vice chairman. by Congress and President Mrs. Lal'Son and her husband, Ford. who retired from the Postal Serv Jerry Gordon Wins Toastmaster ice several years ago, plan to visit Employees should set their Rebecca Wilner has been appointed Contest for the District Area clocks back one hour on Oct . family and friends in Utah and to personnel officer for the Division of spend their winter months in their 27 to compensate for the Research Services. She joined NIH in Jerry Gordon, of the Office of home in Pompano Beach, F la. Science and Health Reports, DRR, change in this area to Eastern 1 970 in the Division of Pe rsonne l was the winner of the Interna Standard Time. Management, She hos also worked in NIH per,sonnel who work the Approximately 17 out of every tional Toastmasters District XIII the Office of the Director, NIH, the 100 Americans - or 35,277,000 - Area Fall 1974 speech contest. tour of duty starting at 12 National Eye Institute, and the Divi midnigiht on Oct. 27 will work suffered from one or more major Mr. Gordon, who is president of sion of Rese arch Resources . Mrs. W il an extra hour that day for allel'lgies in 1973, according to an the NIH Toastmasters Club, won ner received both her B.S. and M.A. which obey will receive over estimate prepared by the National the annual contest in open compe time pay. degrees in Public Pe rsonnel Adminis Institute of Allergy and Infectious tition with other Toastmasters in tration from American University. Diseases. the Bethesda~Chevy Chase area. Page 4 October 23, 1974 THE NIH RECORD DR. GAJDUSEK Dr. Goggins Named Assoc. Dir., Collaborative Noted Experts Discuss (Oontinued from Page 1) Research, NIDR; Dr. Kakehashi Is Prog. Chief These factors led Dr. Gajdusek Kallikrein-Kinin System; to hypothesize that kuru was a familiohereditary degenerative, Evaluate New Research rather than an infectious disease. An international conference on However, the scientists found Chemistry and Biology of the that an animal disease, scrapie (whose symptoms closely resemble Kallikrein-Kinin System in Health and Disease was held from Oct. 20 those of kuru) had similar pathol through today (Oct. 23) in Res ogy to kuru and was transmissible ton, Va. after an unusually long incubation period. Transmission is one of the Scientists from all over bhe world who have made substantial classic proofs of infection. Then, in 1965, the scientists succeeded in contributions to current knowledge about the kallikrein-kinin system passing kuru from infected human attended the conference sponsored brain tissue to chimpanzees after by the Fogarty International Cen a long incubation period. ter and the National Heart and Dr. Gajdusek has written that Lung Institute. kuru undoubtedly spreads by "con It is expected that after the tamination of the population dur Dr. Goggins Or. Kokehoshi evaluation of new research find ing their ritual cannibalistic con ings, t he conferees \viii define sumption of their dead relativ~s a~ Dr. John F. Goggins has been ices Branch, in the Clinical Center appointed to the new position of from 1960 until 1973, when he join problem areas and directions for a rite of respect and mourmng. further research. Men rarely participated in these associate director for Collaborative ed the Extramural Programs as a Research, National Institute of scientist administrator. Kallikreins are enzymes found rites and bherefo.re usually escaped in plasma and in exocrine glands infection. Dental Research. A graduate of Ohio State Uni Dr. Goggins received his pre versity in 1952 and its College of e.g., kidneys, salivary glands, sweat glands, etc. These enzymes Studies Explained dental training at the University Dentistry in 1956, Dr. Kakehashi Today ,t here are several labora began his career in the latter year produce kinins, the most potent of Notre Dame and earned his blood vessel dilator peptides known tory animal models for studying dental degree at Marquette Uni as a dental intern in the PHS kuru and several other fatal CNS versity in 1958. He practiced dent Hospital in Boston. in mammals. degenerative diseases, and the The Iwllikrein-kinin system is istry until 1963, when he returned Joins NIO R Branch believed to play important roles in virus of kuru may be cultivated in to Marquette for graduate training cell culture in v itro. From 1957-1959, he was the dent the regulation of blood pressure in pathology. al officer in charge of the PRS and blood flow and in kidney func One of these is Creutzfeldt In 1965 he joined NIDR and over Outpatient Clinic in Cincinnati. tion. Jakob (a presenile dementia), the next 8 years did research on After his residency in periodontol Kallikreins also promote the ac which is more widespread than the chemistry of connective tissues, ogy at the Medical College of Vir tivation of enzymes involved in kuru. The same basic cellular bones, and teeth, and produced ginia, he joined NIDR's Oral Med coagulation and fibrinolysis and lesions occur in both kuru and nearly 30 scientific papers and ab icine and Surgery Branch where are chemotactic for (i.e. attract) Creutzfeldt-Jakob. But the mole stracts. he worked until last year. certain white blood celJ.s. cular and immunological structure In 1973, Dr. Goggins joined A Diplomate of the American The system may be involved in of both of these viruses remains NIDR's Extramural Programs as Board of Periodontology, Dr. Kake hidden, e.Juding attempts to clas essential hypertensive diseases, chief of the Periodontal and Soft hashi is the author of 20 scientific certain inflammatory reactions and sify them through the usual lab Tissue Diseases Program, encom papers and abstracts on his re diseases, some chronic lung dis oratory techniques. passing both research and training search and clinical activities. He orders, and various shock states. They possess many unique prop activities.· also holds a teaching post as a Further knowledge of the sys erties, such as extreme resistance Dr. Goggins is succeeded in that clinical associate professor at tem, t he mechanisms that activate to heat and ultra-violet irradiation post by Dr. Samuel Kakehashi, Georgetown University School of and inactivate it, and its physiolog which makes bhem atypical among who had been chief, Dental Serv- Dentistry. ical roles could have numerous viruses. clinical applications. Two o,ther slow virus diseases Dr. John J . Pisano, of the NHLI of the nervous system which occur Swedish Council Offers 3 Research Fellowships Hypertension-Endocrine Branch, is in man are subacute sclerosing The Swedish Medical Research An NIH committee will r eview ap serving as program chainnan of panencephalitis and progressive the conference. multifocal leukoencephalopathy. Council is again sponsoring three plications and forward nominations research fellowships to qualified The program included sessions Two other diseases of animals are to the Swedish Medical Research biomedical scientists who are U.S. Council. on characterization of components caused by virus of the same atypi of the kallikrein-kinin system; its cal sort as those of kuru and citizens. Final selections will be made at The 1975 fellowships will provide the May 1975 meeting of the Coun interaction with coagulation and Creutzfeldt-Jakob; scrapie and fibrinolytic mechanisms and with transmissible mink encephalopathy. research experience and training cil, and nominees will be notified at the postdoctoral level in basic of the results shortly t hereafter. various potentiators and inhibitors, Research Continues or clinical sciences related to Further information Jnay be ob and the physiological, pathological, The bunt is now on to determine health. tained from Dr. Eugene L. Wal and clinical significance of the whether obher ,CNS disorders such Candidates must have a doctoral ter, Jr., Swedish Medical Research sysbem. as multiple sclerosis, Parkinson's degree and have been engaged in Fellowship Program, Fogarty In disease, and Huntington's chorea independent research. They must ternational Center, NIH, Bet hesda, Dr. Roy D. Hudson Appointed may also be slow virus infections. present evidence of aptitude in ba Md. 20014. To Director's Advisory Comm. Each year the Dy"er lecturer is sic science or clinical research with Dr. Roy D. Hudson, president of selected by the Director of NIH an active interest in pursuing a Blood Bank Needs Donors: wibh the advice of his senior scien research career. the Hampton Institute in Virginia, tific staff-f.rom among scientists The applicant is responsible for Helps Employees, Families has been appointed to the Advisory who have made important contri arranging his research training The Clinical Center Blood Committee to the Director, NIH. butions in either medical or biolog with the preceptor in Sweden un Bank needs many more donors. Dr. Hudson's term commenced ical research, particularly in t he der whom he will train. Employees who can help Aug. 19 and will end June 30, field of infectious diseases. Fellowships will normally extend should call Ext. '61048 or 1977. The lecture was established in for 12 months after the starting 61049. Dr. Hudson had been associate September 1950 to honor Dr. Rolla date. The fellowship award will All NIH employees and mem professor of medical science at Eugene Dyer, a former NIH cover payment of a stipend and bers of their families are cov Brown University. Director and Director of the Divi transportation expenses. ered by the blood assurance Before that he had served as as sion of Infectious Diseases-now The deadline for receipt of com program. sociate dean and assistant dean of NIAID. pleted applications is Jan. 31, 1975. the graduate school at Brown. THE NIH RECORD October 23, 1974 Page 5
NCI Awards Contracts Attitude May Reveal Sign$ Experts Explain the Role of Supervisors Of Alcoholism in the Home To Improve Pap Test Signs of alcoholism in the In Solving Alcohol, Drug Abuse Problems home are; Alcoll,oli•m cu.vi.- 1/w J'ed,er(t! Gon'1'1w,e11.l /r()m $27.5 mi/li()11 /q For Cancer of Cervix • Needing a drink $550 m:i1Uon ti year in p(tyr,,U losse• "l,mc. Nine contracts to improve the • Gulping drinks one after In tenu.1 of 8')!"i(lt wdl-bei11f/, phJ/8ica! licalth, uml root 10 , ocicly, Pap test for cancer of the cervix another alco!hol is Dr. Arthur L. Schade NIH Visiting Scientists Negoti-aited Agreement Between NIH a·nd Are,a Metal Tr:ades Council Is S,igned by Dr. Stone Retires From NIAID; Program Participants 9/1-Dr. Ryuichiro Hata, J apan, Will Teach in Austria Laboratory of Biochemistry. Spon Dr. Arbhur L. Schade retired sor: Dr. Beverly Peterkofsky, NCI, Bg. 37, Rm. 4Cl 5. last month from the National In stitute of Allergy and Infectious 9/15-Dr. Lena Mikkelsen, Den Diseases, and is now a professor mark, Caries Prevention and Re in the Department of Physiology search Branch. Sponsor: Dr. Rach at the University of Vienna School el Larson, NIDR, Bg. 30, Rm. 528. of Medicine, Austria. 9/24-Dr. Charles E. de la Vega, Dr. Schade was a microbiologist Mexico, Section on Clinical Neuro in the Institute's Office of the pharmacology. Sponsor: Dr. Den Scientific Di1·ector. nis L. Murphy, ND1H, Bg. 10, Rm. In 1952 he joined NIAID where 3S229. he conducted studies on microbial Dr. Minna o Sponsor growth, metabolism, and structure, and on the nature and function of 10/l~Dr. Stuart Brown, United iron-binding pr oteins in blood Kingdom, Laboratory of Biochemi plasma . cal Genetics. Sponsor: Dr. J ohn D. His most recent researeh cen Minna, NHL! , Bg. 36, Rm. l Cl 0. tered on the isolation, purification, 10/ 1- Dr. J ohn C. Donlon, Ire and characterization of the :\1 pro land, Laboratory of Neurochemis tein antigen from the cell wall of t ry. Sponsor: Dr. Seymour Kauf Dr. Stone signs the agreement between NIH and the Washingtan Area Metal t_vpe 4 stn,i n or Streptococcu.~ man, NIMH, Bg. 36, Rm. 3030. Trades Council as membe rs of the negotiating committees watch. pyogN1es. i\[ proteins from o-thr-r 10/ 1 - Dr. Ronald B. Franklin, types of streptococci ar,e being United Kingdom, Lalboratory of The recently negotiated agree members of both teams took their used in experimental vaccines. Chemical Pharmacology. Sponsor: ment between bhe Washington responsibilities seriously and did Studies Explained Dr . James R. Gillette, NHLI, Bg. Area Metal Trades C<,uncil a n ci their homew-0rk well. 10, Rm. 8Nl17. NIH for the Councils' four exclu Dr. Stone felt that this was a At NIAID, Dr. Schade also sively recognized units here was undertook research on siderophilin 10/ 1 - Dr. Janis Z. Gahliks, good agreement with advantages U.S.A,. Envir onn1enbal Toxicology signed by Dr. Robert S. Stone, for both employees and manage and its properties as a nonspecific NIH Director, on Sept. 26. bacterial immunity serum factor Branch. Sponsor: Dr. Judson Spal ment. a determina nt of growth and ding, NIEHS, Research Triangle, The units are Custodial Labor Members of the negotiati.ng com metabolism of staphylococci-and N.C. ers and Related Building Services; !nittees included Paul Price, Wash as an essential iron-binding and 10/ 1- Dr. Kuninobu Kabuto, Ja Grounds Maintenance and Land ington Area Metal Trades Coun donating protein of the host. pan, Laboratory of Chemical Phys scaping; Laundry, and Transpor cil, as chief negotiator. His team In 1964 Dr. Schade was appoint ics. Sponsor: Dr. Herman Ziffer, tation. members were Kermit A. Miller, ed to the Scientific Committee of NIAMDD, Bg. 2, Rm. Bl-06. Dr. Stone congrat ulated the ne Lorraine Hopkins, Robert D. Grey, the Colloquium of Protides of the 10/ 1-Dr. Hiroaki Klllbo, J apan, gotiating committees on their suc Clarence E. Black, Vest Hardwick, Biological Fluids at Bruges, Bel Biochemistry Section. Sponsor: Dr. cess and fine spirit of cooperation. Jr., Willie J. Waller, and Colquitt g ium. ::-.licholas Bachur, NCI, Baltimore The reason negotiations went so H. Yearby. He was honored by that city in Cancer Resea1,ch Center. well, he declared, was because J ames Welch was chief nego 1972 with the presentation of a 10/ 1- Dr . Wu-Tse Liu, Taiwan, tiator for NIH management, and medal for his contributions, over Laborator y of Cell Virology. Spon DR. DEVITA members of his team were Walter a 14-year period, to its annual sor: Dr. Kenneth Chang, NCI, Bg. (Oo11tinrted fro11t Page I) Chakwin, Thomas J . Cook, Frank colloquia. 8, Rm. 207. V. Curtis, Steven M. Galen, Grover In 1939 Dr . Schade received the of the Service. T. Fletcher, and Stanley W. Oliver. Ph.D. degree in biology from Har 10/1 - Dr. Ma r ina M. Mata, From 1963 to 1965 he was a vard University, where he had Spain, Laboratory of Neurophann clinical associate in NCI's Labo1·a earlier received B.A. and ){.A. acology. Sponsor: Dr. Thomas N. tor y of Chemical P harmacology. Chase, NINOS, Bg. 36, Rm. 5A05. degrees. Dr. DcVita has frequently been Before coming to NIAID, he 10/ 1-Dr. Robert M. Moriarty, cited for his accomplishments in worked in private industry. U.S.A., Laboratory of Chemistry. the therapy of Hodgkin's disease Sponsor: D1·. Bernhard Witkop, and non-Hod,gkin's lymphomas, NIAMDD, Bg. 4, Rm. 330. and has played a major role in 10/ 1 - Dr. Jiri Pochobradsky, developing th e new combination Czechoslavakia, Laboratory of drug treatment of that form of Neur ophysiology. Spons-0r: Dr. cancer, as well as of ovarian and Richard Normann, NINOS, Bg. 36, breast cancer. Rm. 2C02. His laboratory resear ch has been Dr. Pouysseg u r at NCI in the interrelationship of d rugs and cell kinetics of human tumors. 10/ 1-Dr. Jacques Pouyssegur, France, Laboratory of Moleeular In 1957 Dr. D.eVita earned his bachelor's degree at the College Dr. Stone discusses the agreement Rio!ogy. Sponsor: Dr. Mark WH with council president Jase ph Frozier lingham, NCI , Bg. 37, Rm. 4B22. of William and )1ary, and his M.D. with distinction at George Wash afte r the signing. 10/ 1- Dr. Ursula Ruhl, Germany, ington University in 1961. Rladiation Oncology Branch. S.pon He will continue to serve as sci awards, including the prestigious sor: Dr. Ra lph J ohnson, NCI , Bg. entific editor of ("(I nt/>/" Che111othe,·· Albert and Mary Lasker Medical 10, Rm. B3B38. apy Report-•. a post h;; has held Research A ward. Dr. Schade, a member of the Public 10/ 2-Dr. Jesus Otero, Spain, since 1970, and associate profes He has been de-corated by the Health Service Cammissioned Carps, Laborator y of Neurophysiology. sor of medicine at the G.W.U. government of Peru, and delivered was honored by the city af Bruges, Sponsor: Dr. Edward V. Evarts, School of Medicine. the F irst Annual Clowes Lecture Be lgium, 2 years aga when the mayor Nil\1H, Bg. 36, Rm. 2D12. Dr. DeVita is a member of num at Rosiwell Park Memorial Insti presented him with a silver medal em 10/8- Dr. Gilbert Jay, United erous professional societies, h as tute in 1973. blazoned with the city's coot-of-arms Kingdom, Section on Infectious written or collaborated on more From 1968 to 1974 he served as for his contributions to the city's an Diseases. Sponsor: Dr. Cephas T. than 156 scientific papers, and is a~~l>eiat{' t•ditor of rlw Journal nf nual colloquia . Patch, NCI, Bg. 10, Rm. 2B56. the recipient of several honors and th,· .\"r,fir,uaf ('r,11,.,,,. fn.•litutr . Pa ge 8 October 23, 1974 THE NIH RECORD Dr. Armstrong Appointed iRetiree Takes He,adache Former NIH Scientists, Administrators 10ut of the Computation To Special NIDR Post Of Retireme:nt Be·nefits Invited to Attend First Alumni Reunion Retirees know that computing NIH will have its first Alumni Reunion for former NIH scientists retirement benefits can give you and administrators next year during the weekend of April 19-20. an acute h :adache. First, you take Announcing the reunion, Dr. Robert S. Stone, NIH Director, noted, the date of retirement, the number "This will be the first event sched of years wJrked, and your highest uled on the NIH campus as part J. Leonard Hooper 3-year annual average salary, cal of the Dapartment of Health, Edu culate the basi: annuity. . .. cation, and Welfare's celebration Appointed Director· Two years ago Joseph Schachter, of the Nation's Bicentennial." an NIAI D statistician contemplat Dr. Sidney Udenfr iend, former Of Exec~ Secretariat ing retirement, decided to take the NIH'er and now Director of the headache out of the process. He J . Leonard Hooper has been ap Roche Institute of Molecular Biol pointed Director of the Executive worked up a computer program ogy, proposed the idea. Re heads for calculating retirement benefits Secretariat in the Office of the Di- a reunion Ad Hoc Committee com rector. under current Civil Service regu posed of 20 other NIH alumni that lations. includes members from sax foreign Mr. Hooper will be assisted by His con:puter program gives a countries. Rosemary Tobin, correspondence printout on 10 points of informa control oflicer, and Celeste Mein tion proje: ting the benefits for a Udenfriend Sends Lette r inger, congressional correspondence given retirement date and at 6- In a letter to alumni, Dr. Uden officer. month intervals for 10 years. friend wrote, "Besides providing The Executive Secretariat, re The program automatically takes Dr. Armstrong's special inte rests in a cordial homecoming atmosphere sponsible to the Dinctor through into aocount any step increases as for seeing old friends, colleagues, clude rescorch on mechon/sms of fluor• they come due and will also con ide's onti-cories activity. students and teachers, and show vert sick leave to years of service. ing the family around the campus, Dr. Wallace D. Armstrong, Re After the basic information is it is hoped that the Reunion will gent$' professor of biochemistry at fed into the computer, it takes emphasize to our national leaders the University of Minnesota Medi only seconds to produce a printout and the great American public the cal School, has been appointed for on an em·iloyee. Computations on important training role this great one year as special assistant to a num•ber· of employees can be Institute has had in the past and the Director of the National In made almost as quickly. continues to have today." 0 stitute of Dental· Research. ldea Wins Award Tentative plans call for regis The appointment was made under The procedure was submitted as tration at the NIH Visitors Center, the Intergovernmental Personnel an employee suggestion, and Mr. to be located in Bldg. 35, on Fri Act, which provides for the tem Schachter was awarded a $50 cash day evening, April 18. The Re porary assignment of personnel prize when the idea was adopted union's main session will be held between executive agencies of the recently by NI H. Two ot her NIH Saturday morning, April 19. F'ederal Government, state and employees who later came up with This will be followed in the local governments, and institutio-ns a similar idea received $25 awards. afternoon with sessions s1:heduled of higher education. When did Mr. Sehachter receive throughout the campus by indi Is Expert on Fluorides the prize? Aug. 8--6 weeks after vidual Institutes for their respec he retired. tive alumni. An expert on fluoride physiolo According to present plans, a Mr. Hooper hos been executive secre gy, Dr. Armstrong is particularly In addition to assuming other large tent will be erected in the interested in the possible mecha ta ry af the Grants Associates Program duties, he will also be acting di area in front of the Visitors Cen in DRG since July 1973. nisms of the anti-caries activity of rector of Intramural Research ter, adjacent to Old Geoi,getown fluoride, as well as recent indica pending appointment of a succes Road between Lincoln Drive and the Associate Director for Admin tions that it is an essential trace sor to Dr. Richard C. Greulich. South Drive. istration, also acts as liaison with element. Dr. Greulich, who has elected to This will be the location for the the Executive Secretariat of the At the Dental Institute he will return to the bench after 8 years Saturday morning main session, Secretary at HE,W, and other De serve primarily as a consultant for in that position, has joined NIDR's special exhibits, a reception late partment Executive Secretariats. research on thestl and other aspects Laboratory of Biological Struc Saturday afternoon, and a possible Other functions of the office in of calcified tissues. ture. farewell brunch on Sunday morn clude re-viewing papers for clarity ing. and timeliness, and assisting NIH Genera.I Schedule of New An,nual Sal·ary R:ates Working with the Ad Hoc Com components in developing docu mittee is a Host Committee of ment$. 8 0 2 3 10 NIH staff appointed by Dr. Stone Mr. Hooper received his B.S. in GS.1 1$ 5,294 $ 5,470 $ 5,646 S 5,822 $ 5,998 S 6,1 74 $ 6,350 $ 6,526 $ 6,702 $ 6,878 with Dr. Thressa Stadtman, Na bacteriology in 1951 from Phila 2 5,996 6,196 6,396 6,596 6,796 6,996 7,196 7,396 7,596 7,796 tional Heart and Lung Institute, delphia College of Pharmacy and 3 6,764 6,989 7,214 7,439 7,664 7,889 8,1 14 8,339 8,564 8,789 and Dr. Karl Piez, National Insti Science. He also attended the Uni 4 7,596 7,849 8, 102 8,355 8,608 8,861 9,114 9,367 9,620 9,873 tute of Dental Research, acting as versity of Maryland and American 5 8,500 8,783 9,066 9,349 9,632 9,915 10,198 10,JBI 10,764 11,047 University. 6 9,473 9,789 10,105 10,421 10,737 11,053 ,11,369 11 .685 12,001 12,317 co-chairpersons. 7 10,520 10,871 11,222 11,573 11,924 12,275 12,626 12 97/ I 3,328 13,679 Grant Is Secretary From 1952 to 1957, Mr. Hooper 8 11,640 12,028 12,416 12,804 13, 192 13,580 13,968 IJ,3~6 l4,74J 15,132 was a bacteriologist with the 9 12,841 13,269 13,697 14, 125 14,553 14,981 15,409 15,8Jf 16,265 16.693 The Office of Communications, Chemical Corps Biological Labor 10 14,117 14,588 15,059 15,530 i6,001 16,472 16,943 17,41, 17,885 18,356 NIH, is serving as Executive Sec atories, Fort Detrick, Md. 11 15,481 15,997 16,513 17,029 17,545 18,061 18,577 19,093 19,609 20, 125 retariat to the Host Committee. 12 18,463 19,078 19,693 20,308 20,923 21,538 22,153 22,768 23,183 23,998 At NIH Mr. Hooper has worked 13 21,816 22,543 23,270 23,997 24,724 25,451 26, 178 26,905 ·27,632 28,359 Replies and inquiries should be for the National Institute of Aller 14 25,581 26,434 27,287 28. 140 28,993 29,846 30,699 31,552 32,405 33,258 directed to Robert Grant, Secre gy and Infectious Diseases as a 15 2?,818 30,812 31,806 32,800 33,794 34,788 35,782 36,776' 37,770" 38,764' tary, NIH F irst Alumni Reunion, bacteriologist and chemist. 16 34,607 35,761 36,915° 38,069. 39,223° 40,377. 41,531 " 42,685° 43,839' c/ o Federation of American Soci In 1963 he joined the Division 17 40,062° 41,397° 42,732° 44,067° 45,402' eties for Experimental Biology, 18 46,336° of Research Grants as a scientific 9650 Rockville Pike, Bethesda, Md. reference analyst in the Statistics • Pny l evels limited to $36.000 l)y Title 5 or the United States Code. 20014. Mr, Grant, Director of Puh and Analysis Branch, transferring ()u Oct. 7. President Ford sl.llned nn E,ecuttvc Order l(rnnt!ng ]'•deral 1 lic Affairs for F ASEB, is an NHL! to the Career Development Review ,•m,F:~r~~~s! \:!~s :i~tt~e u.~r{rt~~tn~;i:!1~:r~~nihe first pay Period (Oct. l;J) alumnus. Branch in 1971 as a staff specialist. n!tcr Oet. 1. NI Fl employe•s--e~cept those 1n speclnl cntc1:ortes-will r eceive the !ucren•c In their Nov. 5 paychecks. * U . S . GOVERNMENT PRINTI NG OFFICE: 1973- S44-802/29