Efficacy of Selective Laser Trabeculoplasty in Primary Angle-Closure Glaucoma: a Randomized Clinical Trial

Supplementary Online Content

Narayanaswamy A, Leung CK, Istiantoro DV, et al. Efficacy of selective laser trabeculoplasty in primary angle-closure glaucoma: a randomized clinical trial. JAMA Ophthalmol. Published online November 27, 2014. doi:10.1001/jamaophthalmol.2014.4893.

eTable 1. Examination Protocol at Baseline and Follow-up Visits

eTable 2. Effectiveness of SLT and PG Therapy in Eyes With Complete Success

eTable 3. Additional Interventions and Complications

This supplementary material has been provided by the authors to give readers additional information about their work.

Downloaded From: https://jamanetwork.com/ on 09/30/2021 eTable 1. Examination Protocol at Baseline and Follow-up Visits

Examination Baseline 1 week 4 weeks 3 months 6 months

Visual Acuity     

Slit-Lamp      Biomicroscopy IOP     

Gonioscopy   

Anterior Segment OCT   (optical coherence tomography) Visual Field  

Heidelberg Retinal   Tomography

Endothelial Cell Count  

Central corneal   thickness

Downloaded From: https://jamanetwork.com/ on 09/30/2021 eTable 2. Effectiveness of SLT and PG Therapy in Eyes With Complete Success

IOP* SLT (30) PGA (43) p-value

Mean absolute reduction (mm Hg) 4.6 ± 2.7 4.6 ± 2.4 0.80 Mean percentage reduction 20.1 ± 9.9 20.1 ± 9.8 0.92  20 % reduction from baseline 18 (60.0%) 23 (53.5%) 0.58  30 % reduction from baseline 5 (16.7 %) 9 (20.9 %) 0.64 * Complete success indicates IOP ≤ 21 mm Hg without medication; SLT - Selective laser trabeculoplasty ; PGA - Prostaglandin analogue

eTable 3. Additional Interventions and Complications

SLT (50) PGA (50) p-value

Additional Medications (%) 11 (22.0%) 4 (8.0 %) 0.05

IOP spike > 5 mm Hg (%) 1 (2.0%) - -

PAS in clock hours at 6 months (SD) 1.02 (2.3) 0.9 (2.4)# 0.279

Mean percentage decrease in ECC from baseline 4.8 (9 .9)º - 0.4 (5.7)a 0.001 (SD) Trabeculectomy - - -

Other Surgeries - - -

SLT –Selective laser trabeculoplasty; PGA- Prostaglandin analogue; PAS - Peripheral anterior synechiae; SLT Group: No difference in Pre Vs. Post laser PAS; p= 0.8; #PG Group: No difference in Pre Vs. Post treatment PAS; p= 0.8; ºp=0.001; ap= 0.8.

Downloaded From: https://jamanetwork.com/ on 09/30/2021