Selenium and Selenoprotein P1 Levels Are Related to Primary Open-Angle
Total Page：16
File Type：pdf, Size：1020Kb
Load more
Recommended publications
-
Short-Term Changes in the Photopic Negative Response Following Intraocular Pressure Lowering in Glaucoma
Glaucoma Short-Term Changes in the Photopic Negative Response Following Intraocular Pressure Lowering in Glaucoma Jessica Tang,1,2 Flora Hui,1 Xavier Hadoux,1 Bernardo Soares,3 Michael Jamieson,3 Peter van Wijngaarden,1–3 Michael Coote,1–3 and Jonathan G. Crowston1,2,4,5 1Glaucoma Research Unit, Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, Australia 2Ophthalmology, Department of Surgery, The University of Melbourne, Melbourne, Australia 3Royal Victorian Eye and Ear Hospital, Melbourne, Australia 4Centre for Vision Research, Duke-NUS Medical School, Singapore, Singapore 5Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore Correspondence: Jessica Tang, PURPOSE. To evaluate the short-term changes in inner retinal function using the photopic Glaucoma Research Unit, Centre for negative response (PhNR) after intraocular pressure (IOP) reduction in glaucoma. Eye Research Australia, Royal Victorian Eye and Ear Hospital, METHODS. Forty-seven participants with glaucoma who were commencing a new or addi- Level 7, Peter Howson Wing, 32 tional IOP-lowering therapy (treatment group) and 39 participants with stable glau- Gisborne St, East Melbourne, VIC coma (control group) were recruited. IOP, visual field, retinal nerve fiber layer thick- 3002, Australia; ness, and electroretinograms (ERGs) were recorded at baseline and at a follow-up visit [email protected]. (3 ± 2 months). An optimized protocol developed for a portable ERG device was used Received: August 29, 2019 to record the PhNR. The PhNR saturated amplitude (Vmax), Vmax ratio, semi-saturation Accepted: June 16, 2020 constant (K), and slope of the Naka–Rushton function were analyzed. Published: August 7, 2020 RESULTS. -
Laser Learning Lecture and Lab: YAG Caps, LPI, And
5/9/17 Overview Laser Learning Lecture and Lab: • Why we use lasers YAG caps, LPI, and SLT • YAG capsulotomy • Laser Peripheral Iridotomy (LPI or PI) Aaron McNulty, O.D., F.A.A.O. • Argon Laser Peripheral Iridoplasty (ALPI) Nate Lighthizer, O.D., F.A.A.O. • Argon Laser Trabeculoplasty (ALT) • Selective Laser Trabeculoplasty (SLT) • Other Laser Trabeculoplasty Why do we use lasers? Posterior Capsular Opacification (PCO) • Vision is decreased from PCO following cataract surgery • Lens capsular bag has an anterior and • Narrow angles/angle closure posterior surface • Glaucoma is progressing in a pt on max meds – Anterior surface usually removed w/ capsulorhexis – Something else needs to be done – Surgery not wanted yet • PCO is the formation of a cloudy membrane • Compliance issues on the posterior surface of the capsular bag • Cost issues following ECCE • Convenience issues – AKA: Secondary cataract • Doctor preference PCO YAG Laser • Incidence: • Nd: YAG laser – Most common complication of post ECCE – Neodymium: Yttrium aluminum garnet laser – 10-80% of eyes following cataract surgery – Can form anywhere from a few days to years post surgery • Tissue interaction: Photodisruptive laser – Younger patients higher risk of PCO – High light energy levels cause the tissues to be reduced – IOL’s to plasma, disintegrating the tissue • Silicone > acrylic – A large amount of energy is delivered into very small focal spots in a very brief duration of time • Prevention: • 4 nsec – – Capsulotomy during surgery No thermal reaction/No coagulation when bv’s are hit – Posterior capsular polishing – Pigment independent* 1 5/9/17 YAG Cap Risks, Complications, YAG Cap Pre-op Exam Contraindications • Visual acuity, glare testing, PAM/Heine lambda Contraindications Risks/complications – Vision 20/30 or worse 1. -
Rendering Hypercomplex Fractals Anthony Atella [email protected]
Rhode Island College Digital Commons @ RIC Honors Projects Overview Honors Projects 2018 Rendering Hypercomplex Fractals Anthony Atella [email protected] Follow this and additional works at: https://digitalcommons.ric.edu/honors_projects Part of the Computer Sciences Commons, and the Other Mathematics Commons Recommended Citation Atella, Anthony, "Rendering Hypercomplex Fractals" (2018). Honors Projects Overview. 136. https://digitalcommons.ric.edu/honors_projects/136 This Honors is brought to you for free and open access by the Honors Projects at Digital Commons @ RIC. It has been accepted for inclusion in Honors Projects Overview by an authorized administrator of Digital Commons @ RIC. For more information, please contact [email protected]. Rendering Hypercomplex Fractals by Anthony Atella An Honors Project Submitted in Partial Fulfillment of the Requirements for Honors in The Department of Mathematics and Computer Science The School of Arts and Sciences Rhode Island College 2018 Abstract Fractal mathematics and geometry are useful for applications in science, engineering, and art, but acquiring the tools to explore and graph fractals can be frustrating. Tools available online have limited fractals, rendering methods, and shaders. They often fail to abstract these concepts in a reusable way. This means that multiple programs and interfaces must be learned and used to fully explore the topic. Chaos is an abstract fractal geometry rendering program created to solve this problem. This application builds off previous work done by myself and others [1] to create an extensible, abstract solution to rendering fractals. This paper covers what fractals are, how they are rendered and colored, implementation, issues that were encountered, and finally planned future improvements. -
Generating Fractals Using Complex Functions
Generating Fractals Using Complex Functions Avery Wengler and Eric Wasser What is a Fractal? ● Fractals are infinitely complex patterns that are self-similar across different scales. ● Created by repeating simple processes over and over in a feedback loop. ● Often represented on the complex plane as 2-dimensional images Where do we find fractals? Fractals in Nature Lungs Neurons from the Oak Tree human cortex Regardless of scale, these patterns are all formed by repeating a simple branching process. Geometric Fractals “A rough or fragmented geometric shape that can be split into parts, each of which is (at least approximately) a reduced-size copy of the whole.” Mandelbrot (1983) The Sierpinski Triangle Algebraic Fractals ● Fractals created by repeatedly calculating a simple equation over and over. ● Were discovered later because computers were needed to explore them ● Examples: ○ Mandelbrot Set ○ Julia Set ○ Burning Ship Fractal Mandelbrot Set ● Benoit Mandelbrot discovered this set in 1980, shortly after the invention of the personal computer 2 ● zn+1=zn + c ● That is, a complex number c is part of the Mandelbrot set if, when starting with z0 = 0 and applying the iteration repeatedly, the absolute value of zn remains bounded however large n gets. Animation based on a static number of iterations per pixel. The Mandelbrot set is the complex numbers c for which the sequence ( c, c² + c, (c²+c)² + c, ((c²+c)²+c)² + c, (((c²+c)²+c)²+c)² + c, ...) does not approach infinity. Julia Set ● Closely related to the Mandelbrot fractal ● Complementary to the Fatou Set Featherino Fractal Newton’s method for the roots of a real valued function Burning Ship Fractal z2 Mandelbrot Render Generic Mandelbrot set. -
Laser Procedures for the Management of Glaucoma and More Handout
4/25/17 Overview Laser Procedures for the Management • Why we use lasers of Glaucoma and More • YAG capsulotomy Nate Lighthizer, O.D., F.A.A.O. • Laser Peripheral Iridotomy (LPI or PI) Assistant Professor, NSUOCO • Argon Laser Peripheral Iridoplasty (ALPI) Assistant Dean, Clinical Care Services • Argon Laser Trabeculoplasty (ALT) Director of CE Chief of Specialty Care Clinics • Selective Laser Trabeculoplasty (SLT) Chief of Electrodiagnostics Clinic • Other Laser Trabeculoplasty [email protected] Why do we use lasers? Posterior Capsular Opacification (PCO) • Vision is decreased from PCO following cataract surgery • Lens capsular bag has an anterior and • Narrow angles/angle closure posterior surface • Glaucoma is progressing in a pt on max meds – Anterior surface usually removed w/ capsulorhexis – Something else needs to be done – Surgery not wanted yet • PCO is the formation of a cloudy membrane • Compliance issues on the posterior surface of the capsular bag • Cost issues following ECCE • Convenience issues – AKA: Secondary cataract • Doctor preference PCO YAG Laser • Incidence: • Nd: YAG laser – Most common complication of post ECCE – Neodymium: Yttrium aluminum garnet laser – 10-80% of eyes following cataract surgery – Can form anywhere from a few days to years post surgery • Tissue interaction: Photodisruptive laser – Younger patients higher risk of PCO – High light energy levels cause the tissues to be reduced – IOL’s to plasma, disintegrating the tissue • Silicone > acrylic – A large amount of energy is delivered into very small focal spots in a very brief duration of time • Prevention: • 4 nsec – – Capsulotomy during surgery No thermal reaction/No coagulation when bv’s are hit – Posterior capsular polishing – Pigment independent* 1 4/25/17 YAG Cap Risks, Complications, YAG Cap Pre-op Exam Contraindications • Visual acuity, glare testing, PAM/Heine lambda Contraindications Risks/complications – Vision 20/30 or worse 1. -
Bjophthalmol-2020-318090 1..2
At a glance Br J Ophthalmol: first published as 10.1136/bjophthalmol-2020-318090 on 26 October 2020. Downloaded from Highlights from this issue doi:10.1136/bjophthalmol-2020-318090 Keith Barton , James Chodosh , Jost B Jonas , Editors in chief Glaucoma in the Northern Ireland Cohort The effect of partial posterior vitreous Comparison of OCT angiography in for the Longitudinal Study of Ageing detachment on spectral-domain optical children with a history of intravitreal (NICOLA): cohort profile, prevalence, coherence tomography retinal nerve fibre injection of ranibizumab vs laser awareness and associations (seepage1492) layer thickness measurements photocoagulation for retinopathy of The crude prevalence of glaucoma in (seepage1524) prematurity (see page 1556) Northern Ireland of 2.83% (95% CI Among glaucoma suspects, eyes with par- In this cross-sectional study, we found that 2.31%, 3.46%) is comparable to other tial posterior vitreous detachments, com- the central foveal vessel length density and European population-based studies. pared to eyes without, were associated perfusion density, the foveal avascular Approximately two thirds of people with with greater average, superior, and inferior zone area and central foveal thicknesses glaucoma were undiagnosed. Associations retinal nerve fibre layer thickness of children who had undergone different with glaucoma were consistent with cur- measurements. treatments, might vary. rent understanding of the disease. Three-year follow-up of choroidal Comparison of central visual sensitivity Selective -
A Review of Selective Laser Trabeculoplasty: Recent Findings and Current Perspectives
Ophthalmol Ther DOI 10.1007/s40123-017-0082-x REVIEW A Review of Selective Laser Trabeculoplasty: Recent Findings and Current Perspectives Yujia Zhou . Ahmad A. Aref Received: January 17, 2017 Ó The Author(s) 2017. This article is published with open access at Springerlink.com ABSTRACT explored, revealing that minor modifications may lead to a more favorable or safer clinical Selective laser trabeculoplasty (SLT) has been outcome. The utilization of postoperative widely used in the clinical management of medications remains controversial based on the glaucoma, both as primary and adjunctive current evidence. A short-term IOP increase treatment. As new evidence continues to arise, may complicate SLT and can also persist in we review the current literature in terms of certain cases such as in exfoliation glaucoma. indications and efficacy, surgical technique, The efficacy and safety of repeat SLT are shown postoperative care, repeatability, and compli- in multiple studies, and the timing of repeat cations of this therapy. SLT has been shown to procedures may affect the success rate. be effective in various glaucomas, including primary open-angle glaucoma (POAG), nor- mal-tension glaucoma (NTG), steroid-induced Keywords: Glaucoma; Intraocular pressure; glaucoma, pseudoexfoliation glaucoma (PXFG), Laser; Selective laser trabeculoplasty and primary angle-closure glaucoma (PACG), as well as other glaucoma subtypes. Relatively high preoperative intraocular pressure (IOP) INTRODUCTION may predict surgical success, while other parameters that have been studied do not seem Intraocular pressure (IOP) reduction is the to affect the outcome. Different techniques for mainstay of therapy for glaucomatous optic performing the procedure have recently been neuropathy. Selective laser trabeculoplasty (SLT) has been widely employed for this pur- Enhanced content To view enhanced content for this pose over the past several years as both a pri- article go to http://www.medengine.com/Redeem/ mary and adjunctive treatment [1]. -
Laser Trabeculoplasty for Open-Angle Glaucoma a Report by the American Academy of Ophthalmology
Laser Trabeculoplasty for Open-Angle Glaucoma A Report by the American Academy of Ophthalmology John R. Samples, MD,1 Kuldev Singh, MD, MPH,2 Shan C. Lin, MD,3 Brian A. Francis, MD,4 Elizabeth Hodapp, MD,5 Henry D. Jampel, MD, MHS,6 Scott D. Smith, MD, MPH7 Objective: To provide an evidence-based summary of the outcomes, repeatability, and safety of laser trabeculoplasty for open-angle glaucoma. Methods: A search of the peer-reviewed literature in the PubMed and the Cochrane Library databases was conducted in June 2008 and was last repeated in March 2010 with no date or language restrictions. The search yielded 637 unique citations, of which 145 were considered to be of possible clinical relevance for further review and were included in the evidence analysis. Results: Level I evidence indicates an acceptable long-term efficacy of initial argon laser trabeculoplasty for open-angle glaucoma compared with initial medical treatment. Among the remaining studies, level II evidence supports the efficacy of selective laser trabeculoplasty for lowering intraocular pressure for patients with open-angle glaucoma. Level III evidence supports the efficacy of repeat use of laser trabeculoplasty. Conclusions: Laser trabeculoplasty is successful in lowering intraocular pressure for patients with open- angle glaucoma. At this time, there is no literature establishing the superiority of any particular form of laser trabeculoplasty. The theories of action of laser trabeculoplasty are not elucidated fully. Further research into the differences among the lasers used in trabeculoplasty, the repeatability of the procedure, and techniques of treatment is necessary. Financial Disclosure(s): Proprietary or commercial disclosure may be found after the references. -
Cosmetic Lateral Canthoplasty: Lateral Topic Canthoplasty to Lengthen the Lateral Canthal Angle and Correct the Outer Tail of the Eye
Cosmetic Lateral Canthoplasty: Lateral Topic Canthoplasty to Lengthen the Lateral Canthal Angle and Correct the Outer Tail of the Eye Soo Wook Chae1, Byung Min Yun2 1BY Plastic Surgery Clinic, Seoul; 2Department of Plastic and Reconstructive Surgery, Jeju National University, Jeju, Korea There are many women who want larger and brighter eyes that will give a favorable impression. Correspondence: Soo Wook Chae Surgical methods that make the eye larger and brighter include double eyelidplasty, epican- BY Plastic Surgery Clinic, Wookyung Bldg. 5th Fl., 466 Apgujeong-ro, thoplasty, as well as lateral canthoplasty. Double eyelidplasty produces changes in the vertical Gangnam-gu, Seoul 06015, Korea dimension of the eyes, whereas epicanthoplasty and lateral canthoplasty create changes in Tel: +82-2-541-5522 the horizontal dimension of the eyes. Epicanthoplasty, a surgical procedure which enlarges Fax: +82-2-545-8743 the eye horizontally, is performed at the inner corner of the eye, whereas lateral canthoplasty E-mail: [email protected] enlarges the outer edge of the eye. In particular, if the slant of the palpebral fissure is raised and the horizontal dimension of the palpebral fissure is short, adjusting the slant of the pal- pebral fissure through lateral canthoplasty can achieve an enlargement of eye width and smoother features. Depending on the patient’s condition, even better results can be achieved if this procedure is performed in conjunction with other procedures, such as double eyelid- plasty, epicanthoplasty, eye roll formation surgery, fat graft, and facial bone contouring sur- gery. In this paper, the authors will introduce in detail their surgical method for a cosmetic lateral canthoplasty that lengthens the lateral canthal angle and corrects the outer tail of the eyes, in order to ease the unfavorable impression. -
Cataract Surgery
Cataract surgery From Wikipedia, the free encyclopedia Jump to: navigation, search This article includes a list of references, related reading or external links, but its sources remain unclear because it lacks inline citations. Please improve this article by introducing more precise citations. (May 2011) Cataract surgery Intervention Cataract in Human Eye- Magnified view seen on examination with a slit lamp ICD-9-CM 13.19 MeSH D002387 Cataract surgery is the removal of the natural lens of the eye (also called "crystalline lens") that has developed an opacification, which is referred to as a cataract. Metabolic changes of the crystalline lens fibers over time lead to the development of the cataract and loss of transparency, causing impairment or loss of vision. Many patients' first symptoms are strong glare from lights and small light sources at night, along with reduced acuity at low light levels. During cataract surgery, a patient's cloudy natural lens is removed and replaced with a synthetic lens to restore the lens's transparency.[1] Following surgical removal of the natural lens, an artificial intraocular lens implant is inserted (eye surgeons say that the lens is "implanted"). Cataract surgery is generally performed by an ophthalmologist (eye surgeon) in an ambulatory (rather than inpatient) setting, in a surgical center or hospital, using local anesthesia (either topical, peribulbar, or retrobulbar), usually causing little or no discomfort to the patient. Well over 90% of operations are successful in restoring useful vision, with a low complication rate.[2] Day care, high volume, minimally invasive, small incision phacoemulsification with quick post-op recovery has become the standard of care in cataract surgery all over the world. -
Sphere Tracing, Distance Fields, and Fractals Alexander Simes
Sphere Tracing, Distance Fields, and Fractals Alexander Simes Advisor: Angus Forbes Secondary: Andrew Johnson Fall 2014 - 654108177 Figure 1: Sphere Traced images of Menger Cubes and Mandelboxes shaded by ambient occlusion approximation on the left and Blinn-Phong with shadows on the right Abstract Methods to realistically display complex surfaces which are not practical to visualize using traditional techniques are presented. Additionally an application is presented which is capable of utilizing some of these techniques in real time. Properties of these surfaces and their implications to a real time application are discussed. Table of Contents 1 Introduction 3 2 Minimal CPU Sphere Tracing Model 4 2.1 Camera Model 4 2.2 Marching with Distance Fields Introduction 5 2.3 Ambient Occlusion Approximation 6 3 Distance Fields 9 3.1 Signed Sphere 9 3.2 Unsigned Box 9 3.3 Distance Field Operations 10 4 Blinn-Phong Shadow Sphere Tracing Model 11 4.1 Scene Composition 11 4.2 Maximum Marching Iteration Limitation 12 4.3 Surface Normals 12 4.4 Blinn-Phong Shading 13 4.5 Hard Shadows 14 4.6 Translation to GPU 14 5 Menger Cube 15 5.1 Introduction 15 5.2 Iterative Definition 16 6 Mandelbox 18 6.1 Introduction 18 6.2 boxFold() 19 6.3 sphereFold() 19 6.4 Scale and Translate 20 6.5 Distance Function 20 6.6 Computational Efficiency 20 7 Conclusion 2 1 Introduction Sphere Tracing is a rendering technique for visualizing surfaces using geometric distance. Typically surfaces applicable to Sphere Tracing have no explicit geometry and are implicitly defined by a distance field. -
Computer-Generated Music Through Fractals and Genetic Theory
Ouachita Baptist University Scholarly Commons @ Ouachita Honors Theses Carl Goodson Honors Program 2000 MasterPiece: Computer-generated Music through Fractals and Genetic Theory Amanda Broyles Ouachita Baptist University Follow this and additional works at: https://scholarlycommons.obu.edu/honors_theses Part of the Artificial Intelligence and Robotics Commons, Music Commons, and the Programming Languages and Compilers Commons Recommended Citation Broyles, Amanda, "MasterPiece: Computer-generated Music through Fractals and Genetic Theory" (2000). Honors Theses. 91. https://scholarlycommons.obu.edu/honors_theses/91 This Thesis is brought to you for free and open access by the Carl Goodson Honors Program at Scholarly Commons @ Ouachita. It has been accepted for inclusion in Honors Theses by an authorized administrator of Scholarly Commons @ Ouachita. For more information, please contact [email protected]. D MasterPiece: Computer-generated ~1usic through Fractals and Genetic Theory Amanda Broyles 15 April 2000 Contents 1 Introduction 3 2 Previous Examples of Computer-generated Music 3 3 Genetic Theory 4 3.1 Genetic Algorithms . 4 3.2 Ylodified Genetic Theory . 5 4 Fractals 6 4.1 Cantor's Dust and Fractal Dimensions 6 4.2 Koch Curve . 7 4.3 The Classic Example and Evrrvday Life 7 5 MasterPiece 8 5.1 Introduction . 8 5.2 In Detail . 9 6 Analysis 14 6.1 Analysis of Purpose . 14 6.2 Analysis of a Piece 14 7 Improvements 15 8 Conclusion 16 1 A Prelude2.txt 17 B Read.cc 21 c MasterPiece.cc 24 D Write.cc 32 E Temp.txt 35 F Ternpout. txt 36 G Tempoutmid. txt 37 H Untitledl 39 2 Abstract A wide variety of computer-generated music exists.