Anti-SEMA6A (Aa 36-65) Polyclonal Antibody (DPABH-11186) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-SEMA6A (aa 36-65) polyclonal antibody (DPABH-11186) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description Cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling. Required for normal granule cell migration in the developing cerebellum. Promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the developing central nervous system. Can act as repulsive axon guidance cue. Has repulsive action towards migrating granular neurons. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation.

Immunogen Synthetic peptide within Human Sema6A aa 36-65 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: Q9H2E6

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Purification Immunogen affinity purified

Conjugate Unconjugated

Applications WB

Format Liquid

Size 400 μl

Buffer Constituent: 99% PBS

Preservative 0.09% Sodium Azide

Storage Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

GENE INFORMATION

Gene Name SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin)

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Official Symbol Sema6A

Synonyms SEMA6A; sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A; SEMAQ; semaphorin-6A; HT018; KIAA1368; SEMA; sema VIa; SEMA6A1; SEMA6A-1; semaphorin VIA; semaphorin 6A-1; semaphorin-6A-1; VIA;

Entrez Gene ID 57556

Protein Refseq NP_065847

UniProt ID Q9H2E6

Chromosome Location 5q23

Pathway Axon guidance; Developmental Biology; Other semaphorin interactions; Semaphorin interactions;

Function protein binding; receptor activity; semaphorin receptor binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]