Michelle R. Dawson, Ph.D. Molecular Pharmacology, Physiology, and Biotechnology and the School of Engineering Brown University 1

Michelle R. Dawson, Ph.D.

Molecular Pharmacology, Physiology, and Biotechnology and the School of Engineering Brown University 171 Meeting St. Box G-B, Providence, RI 02912 Phone: (401) 863-6829; Fax: (401) 863-1595 Email: [email protected]

Brown Website: https://www.brown.edu/research/labs/dawson/home Faculty Profile: https://vivo.brown.edu/display/mdawson2 Dawson Lab Website: https://www.dawsoncellbiophysics.com Twitter: @DawsonStemCell @CellBiophysics Linkedin: https://www.linkedin.com/in/michelle-r-dawson-a6a7351/ Google Scholar: https://scholar.google.com/citations?user=_u4XlD0AAAAJ&hl=en

ACADEMIC APPOINTMENTS

Assistant Professor, July 2016 – current Molecular Pharmacology, Physiology, & Biotechnology, Brown University School of Engineering, Brown University Faculty Trainer: MPP, MCB, BME, Pathobiology

Assistant Professor, November 2008 – June 2016 School of Chemical & Biomolecular Engineering, Georgia Institute of Technology (GT) Faculty appointments: Petit Institute for Bioengineering & Bioscience, Bioengineering Graduate Program, Wallace H. Coulter Department of Biomedical Engineering, School of Biology

Postdoctoral Research Fellow, June 2005 – October 2008 Massachusetts General Hospital, Harvard Medical School, and Edwin L. Steele Lab Advisor: Rakesh K. Jain

EDUCATION

Ph.D. Chemical and Biomolecular Engineering, January 2000 – May 2005 Johns Hopkins University, Baltimore, MD, May 2005. Advisor: Justin Hanes. Ph.D. Thesis: Mucosal Barriers to Non-Viral Gene Delivery in the Cystic Fibrotic Lung.

B.S. Biomedical Engineering, Louisiana Tech University, Ruston, LA, May 1999

December 18, 2018

PUBLICATIONS

Book Chapters

1. Ghosh D, Dawson M (2018). Microenvironment Influences Cancer Cell Mechanics from Tumor Growth to Metastasis. Biomechanics in Oncology, 69-90. Advances in Experimental Medicine and Biology, Volume 1092. Edited by Konstantopoulos, Dong, and Kuhn. Springer Publishing. 2. Dawson M, Ghosh D (2016). Mucosal Barriers. Drug Delivery Across Physiological Barriers. Edited by Silvia Muro 155-180, Pan Stanford Publishing. 3. Dawson M, Tseng Y, Lee J, McAndrews K (2014). Intracellular Particle Tracking Rheology. Handbook of Imaging in Biological Mechanics. Edited by Corey Neu and Guy Genin, 381-388, CRC Press. 4. Hanes J, Dawson M, Har-el Y, Suh J, Fiegel J (2003). Gene delivery to the lung. Pharmaceutical Inhalation Aerosol Technology, Edited by AJ Hickey, 2nd Ed., 489-539. Marcel Dekker Incorporated.

Refereed Journal Articles (H-index 20, ~2000 Citations)

1. Quach N, Eggert M, Ingram L, Ghosh D, Sheth S, Nagy T, Dawson M, Arnold R, Cummings B. Paradoxical Role of Glypican-1 in Prostate Cancer Cell and Tumor Growth. Accepted to Scientific Reports (2018). 2. Ghosh D, Quach N, Xuan B, Mejia-Pena C, Dawson M. Mesenchymal Stem Cell Aging and Senescence Associated Extracellular Matrix. Revising for submission to Scientific Reports. 3. Ghosh D, Quach N, Xuan B, Mejia-Pena C, Dawson M. Senescence alters tumor microenvironment interactions forcing cancer progression. Revising for submission to PNAS. 4. Xuan B, Ghosh D, Cheney E, Clifton E, Dawson M. Dysregulation in Actin Cytoskeletal Organization Drives Increased Stiffness and Migratory Persistence in Polyploidal Giant Cancer Cells. Scientific reports 8 (1), 11935 (2018). 5. Ali M, Wu Y, Ghosh D, Do B, Chen K, Dawson M, Fang N, Sulchek T, El-Sayed M. Gold Nanoparticles trapped at Nucleus Membrane Enhance the Nuclear Stiffness Causing Inhibition of Cancer Cell Migration, Invasion, and Motility by Modifying Nuclear Lamin A/C Protein. ACS Nano 11: 3716-26 (2017). 6. Ghosh D, McGrail D, Dawson M. TGF-β1 Pretreatment Improves the Function of Mesenchymal Stem Cells in the Wound Bed. Microenvironment Derived Stem Cell Plasticity. Frontiers in Cell and Developmental Biology 5: 28 (2017). 7. McAndrews K, Yi J, McGrail D, Ravikumar N, Dawson M. Mesenchymal Stem Cells Induce Directional Migration of Invasive Breast Cancer Cells through TGF-β. Scientific Reports 5: 16,941 (2015). 8. McGrail D, Patel K, Khambati N, Pithadia K, Dawson M. Utilizing Temporal Variations in Chemotherapeutic Response to Improve Breast Cancer Treatment Efficacy. AIMS Bioengineering 2(4): 310-23 (2015).

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9. McGrail D, McAndrews K, Brandenburg C, Ravikumar N, Kieu Q, Dawson M. Osmotic regulation is required for cancer cell survival under solid stress. Biophysical Journal 109(7): 1334-7 (2015). 10. McAndrews K, Yi J, McGrail D, Dawson M. Enhanced Adhesion of Stromal Cells to Invasive Cancer Cells Regulated by Cadherin 11. ACS Chemical Biology 10(8):1932–38 (2015). 11. McGrail D, Kieu Q, Iandoli J, Dawson M. Actomyosin Tension as a Determinant of Metastatic Cancer Mechanical Tropism. Physical Biology 12(2):026001 (2015). Featured article. 12. McGrail D, Qi M, Khambhati N, Patel, K, Dawson M. Alterations in Ovarian Cancer Cell Adhesion Drive Taxol Resistance by Increasing Microtubule Dynamics in a FAK- dependent Manner. Scientific Reports 5:9529 (2015). 13. McGrail D, Kieu M, Mezencev R, McDonald J, Dawson M. SNAIL-induced epithelial-to- mesenchymal transition produces concerted biophysical changes from altered cytoskeletal gene expression. FASEB J 29(4):1280-9 (2015). 14. Datla S, McGrail D, Lyle A, Pounkova L, Hilenski1 L, Dawson M, Lassègue B, and Griendling K. Poldip2 Controls Vascular Smooth Muscle Cell Migration by Regulating Focal Adhesion Turnover and Polarization. Applied Journal of Physiology 307 (7): H945- 57 (2014). 15. McAndrews K, McGrail D, Quach N, Dawson M. Spatially coordinated changes in intracellular rheology and extracellular force exertion during mesenchymal stem cell differentiation. Physical Biology 11: 056004 (2014). 16. McAndrews K, Kim F, Lam T, McGrail D, Dawson M. Architectural and Mechanical Cues Direct Mesenchymal Stem Cell Interactions with Cross-Linked Gelatin Scaffolds. Tissue Engineering Part A, 20(23-24):3252-60 (2014). 17. McGrail D, Kieu Q, Dawson M. The Malignancy of Metastatic Ovarian Cancer Cells is Increased on Soft Matrices Through a Mechanosensitive Rho-ROCK Pathway. Journal of Cell Science 127, 2621-2626 (2014). Featured on the Cover. 18. Ghosh D, Lilli L, McGrail D, Matyunina L, McDonald J, Dawson M. TGF−β1 Induced Stiffening of Mesenchymal Stem Cells Depends on PDGF-BB Signaling, Stem Cells and Development 23(3): 245-61 (2014). 19. Don-Salu-Hewage1 A; Chan A; McAndrews K; Chetram M; Dawson M; Bethea D; Hinton C. Cysteine (C)-X-C Receptor 4 Undergoes Transportin 1-Dependent Nuclear Localization and is Functional at the Nucleus of Metastatic Prostate Cancer Cells, PLoS ONE 7 (8): e57194 (2013). 20. McGrail D, McAndrews K, Dawson M. Biomechanical Analysis Predicts Decreased Human Mesenchymal Stem Cell Function before Molecular Differences, Experimental Cell Research 319: 684-696 (2013). 21. McGrail D, Ghosh D, Quach N, Dawson M. Differential Mechanical Response of Mesenchymal Stem Cells and Fibroblasts to Tumor-Secreted Soluble Factors, PLoS ONE 7 (3): e33248 (2012). 22. Suk, JS, Lai S, Dawson M, Boylan, N, Boyle M, Hanes J. Rapid transport of muco-inert nanoparticles in CF sputum treated with NAC, Nanomedicine 6 (2): 365-75 (2011).

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23. Dawson M, Chae S, Jain RK, Duda D. Cell Lineage-dependent Effects of Bone Marrow Stromal Cells on Tumor Progression, American Journal of Cancer Research 1(2):144-154 (2011). 24. Kozin, SV, Kamoun, WS, Huang, Y, Dawson, M, Jain, RK, Duda, DG. Rapid macrophage infiltration after local irradiation facilitates tumor re-growth whereas TEMs and not EPCs recruitment facilitates relapse of irradiated tumors, Cancer Research 70(14): 5679-85 (2010) (>140 citations). 25. Dawson M, Duda D, Chae S, Fukumura D, Jain RK. VEGFR1 activity modulates myeloid cell infiltration in growing lung metastases but is not required for spontaneous metastasis formation, PLoS ONE 4(9): e6525 (2009). 26. Tang B, Dawson M, Lai S, Wang YY, Suk, JS, Yang M, Zeitlin P, Boyle M, Fu J, Hanes J. Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier, Proceedings of the National Academy of Sciences 106(46):19268-73 (2009). Featured on the Cover (>250 citations). 27. Dawson M, Duda D, Fukumura D, Jain RK. VEGFR1-activity independent metastasis formation, Nature 461: E4 (2009). 28. Perentes JY, McKee TD, Ley CD, Mathiew H, Dawson M, Padera TP, Munn LL, Jain RK, Boucher Y. In vivo imaging of extracellular matrix remodeling by tumor-associated fibroblasts, Nature Methods, 6(2):143-5 (2009) (>100 citations). 29. Suh J, Dawson M, Hanes J. (2005). Real-time particle tracking: Applications to drug and gene delivery, Advanced Drug Delivery Reviews 57:63-78 (>200 citations). 30. Dawson M, Krauland E, Wirtz D, Hanes J. (2004). Transport of polymeric nanoparticle gene carriers in gastric mucus, Biotechnology Progress, 20(3):851-857 (>100 citations). 31. Dawson M, Wirtz D, and Hanes J. (2003). Enhanced viscoelasticity of human cystic fibrotic sputum correlates with increasing microheterogeneity in particle transport, Journal of Biological Chemistry, 278:50393-50401 (>200 citations).

Abstracts (National/International Meetings)

1. Dawson M, Ghosh D (2018). Cellular Senescence Alters Tumor Microenvironment Interactions Forcing Cancer Progression. Gordon Research Conference: Signal Transduction by Engineered Extracellular Matrices, July 22-27, 2018, Andover, NH (MD, GRC Poster Presentation). 2. Dawson M, Ghosh D, Xuan B (2018). Biophysics of Giant Polyploidal Cancer Cells that Form in an Aging Tumor Stroma. Cellular and Molecular Bioengineering (CMBE) Conference, January 2-6, 2018, Key Largo, FL (MD, CMBE Poster Presentation). 3. Dawson M, Xuan B, Ghosh D (2018). Biophysics of polyploidal cancer cells in an aging stroma. Cancer Research 78 (13 Supplement), 1315-1315 (MD, AACR Poster Presentation). 4. Bedoya S, Ghosh D, Dawson M (2018). Mechanosensitivity Analysis of Breast Cancer Tumor Cells from Needle Biopsy. FASEB JOURNAL 32 (1). 5. Quach N, Eggert M, Ghosh D, Dawson M, Arnold R, Cummings B (2017). Glypican-1: A tumor suppressor or an oncogene in human bone metastatic prostate cancer cells. Cancer Research 77 (13 Supplement), 4465-4465.

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6. Gupta S, Ghosh D, Schutte S, Dawson M (2016). 3D Spheroid Model of Fibroid Growth: Quantifying the Effect of Mechanical Environment Stiffness on Development. Obstetrics & Gynecology 127, 46S (SG, Poster Presentation). 7. McAndrews K, Kim M, Lam TY, McGrail D, Dawson M (2014). Mechanical and Architectural Properties of Cross-Linked Gelatin Scaffolds Direct the Differentiation of Mesenchymal Stem Cells. American Institute of Chemical Engineers Annual Meeting (KM, Podium Presentation). 8. McAndrews K, Kim M, Lam TY, McGrail D, Dawson M (2014). Directed Differentiation of Mesenchymal Stem Cells on Cross-linked Gelatin Scaffolds by Mechanical and Architectural Cues. Biomedical Engineering Society Annual Meeting (KM, Poster Presentation). 9. McGrail D, Kieu Q, Iandoli J, Dawson M (2014). Mechanical Tropism in Metastatic Cancer Cells Determined Through Cytoskeletal Tension. American Institute of Chemical Engineers Annual Meeting (DM, Poster Presentation). 10. McGrail D, Qi M, Patel K, Khambati N, Dawson M (2014). Taxol Resistance Exacerbates Ovarian Cancer Progression by Altering Adhesion Kinetics and Strength. American Institute of Chemical Engineers Annual Meeting (DM, Podium Presentation). 11. McGrail D, Kieu Q, Iandoli J, Dawson M (2014). Mechanical Tropism in Metastatic Cancer Mechanical Tropism is Controlled by Cytoskeletal Tension. Biomedical Engineering Society Annual Meeting (DM, Podium Presentation). 12. McGrail D, Qi M, Patel K, Khambati N, Dawson M (2014). Taxol Resistance Exacerbates Ovarian Cancer Progression by Altering Adhesion Kinetics and Strength. Biomedical Engineering Society Annual Meeting (DM, Poster Presentation). 13. Ghosh D, McGrail D, Dawson M (2014). TGFβ1 Pretreatment Improves the Function of Mesenchymal Stem Cells in the Wound Bed. Biomedical Engineering Society Annual Meeting (MD, Podium Presentation). 14. Jampol R, Ghosh D, Dawson M (2014). The Effect of Soluble Factors on the Morphological, Adhesive, and Mechanical Properties of Human Bone Marrow Endothelial Cells. American Institute of Chemical Engineers Annual Meeting (MD, Podium Presentation). 15. Dawson M (2013). Mechanics and Malignancy: Biophysical Approaches for Investigating the Tumor Microenvironment. Bulletin of American Physical Society 58 (MD, Podium Presentation). 16. Khalil M, Lassegue B, McGrail D, Datla R, Martin A, Dawson M, Griendling K (2013). Poldip 2 Regulates Adhesion and Spreading of Vascular Smooth Muscle Cells Through Its Interaction with Kindlin-2 and Talin. Circulation 126 (21): A11759 (MK, Podium Presentation). 17. McAndrews K, McGrail D, Quach N, Dawson M (2013). Utilizing Multiple Particle Tracking Microrheology and Traction Force Microscopy to Monitor Mechanical Progression of Differentiating Mesenchymal Stem Cells. American Institute of Chemical Engineers Annual Meeting (K.M., Podium Presentation). 18. McGrail D, Kieu Q, Dawson M (2013). Mechanical Tropism in Metastatic Ovarian Cancer Cells. American Institute of Chemical Engineers Annual Meeting (DM, Podium Presentation).

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19. McGrail D, Kieu Q, Dawson M (2013). Ovarian Cancer Tropism for Compliant Matrices. Gordon Research Conference, Motility and Contractility (MD, Poster Presentation). 20. McGrail D, Kieu Q, Iandoli J, Dawson M (2013). Low Matrix Rigidity Enhances Malignant Phenotype in Ovarian Cancer Cells. Annual National Symposium on Prostate Cancer (QK, Poster Presentation). 21. Ghosh D, Lilli L, McGrail D, Matyunina L, McDonald J, Dawson M (2013). TGF-β1 Induced Stiffening of Mesenchymal Stem Cells Depends on PDGF-BB Signaling. Biomedical Engineering Society Annual Meeting (DG, Podium Presentation). 22. Ghosh D, McGrail D, Dawson M (2013). PDGF and TGF-β1 Crosstalk Is Essential for Mesenchymal Stem Cell Stiffening. American Institute of Chemical Engineers Annual Meeting (DG, Podium Presentation). 23. Rodriguez K, Khambhati N, Dawson M (2013). The Intracellular Mechanical Response of Mesenchymal Stem Cells to Oxidative Stress Used to Compare Vertebrate Animal Models of Stem Cell Homing. American Institute of Chemical Engineers Annual Meeting (KR, Podium Presentation). 24. Jampol R, Ghosh D, Rodriguez K, Dawson M (2013). Using Luciferase Expression to Quantify the Accumulation of Genetically Engineered Mesenchymal Stem Cells in Murine Tumors. American Institute of Chemical Engineers Annual Meeting (RJ, Podium Presentation). 25. Datla S, McGrail D, Dawson M, Lassègue B, Griendling K (2012). Poldip2, a Nox4 Interacting Protein, Regulates Vascular Smooth Muscle Cell Migration via RhoA- dependent Focal Adhesion Turnover. Gordon Research Conference (SD, Podium Presentation). 26. McAndrews K, McGrail D, Quach N, Dawson M (2012). Mechanical Forces Generated by Mesenchymal Stem Cells Undergoing Differentiation on Hard and Soft Substrates. Biomedical Engineering Society Annual Meeting (KM, Poster Presentation). 27. McGrail D, McAndrews K, Dawson M (2012). Mechanical Cues as Predictors of Human Mesenchymal Stem Cell Therapeutic Capacity. Biomedical Engineering Society Annual Meeting (DM, Podium Presentation). 28. McGrail D, McAndrews K, Dawson M (2012). Culture-associated mechanical changes of human mesenchymal stem cells. American Chemical Society Annual Meeting (MD, Podium Presentation). 29. Ghosh D, McGrail D, Dawson M (2012). Soluble growth factor induced mechanical changes regulate the migration of mesenchymal stem cells to tumors. American Chemical Society Annual Meeting (MD, Podium Presentation). 30. Rodriguez K, Ghosh D, McAndrews K, McGrail D, Dawson M (2011). Optimization of Mesenchymal Stem Cell Migration in the Wound Bed. American Institute of Chemical Engineers Annual Meeting (KR, Podium Presentation). 31. Ghosh D, Dawson M (2011). Soluble Growth Factors Mediate Mesenchymal Stem Cell Migration to Tumors. American Institute of Chemical Engineers Annual Meeting (DG, Podium Presentation). 32. McGrail D, McAndrews K, Dawson M (2011). Differential Mechanical Response of Human and Murine Mesenchymal Stem Cells: Implications for Therapeutic Applications. Biomedical Engineering Society Annual Meeting (KM, Poster Presentation).

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33. Ghosh D, McGrail D, McAndrews K, Dawson M (2011). Toward the Development of New Strategies for the Delivery of MSC-Based Therapeutics. Biomedical Engineering Society Annual Meeting (KM, Poster Presentation). 34. McGrail D, Ghosh D, Dawson M (2011). Mechanical Changes of Senescent Mesenchymal Stem Cells. Controlled Release Society (DM, Podium Presentation). 35. Ghosh D, McGrail D, Dawson M (2011). Mechanically-Optmized Murine Mesenchymal Stem Cells Accumulate in 4T1 Mammary Tumors. Controlled Release Society (DG, Poster Presentation). 36. McGrail D, Zuelke D, Ghosh D, Dawson M (2010). Probing the Microrheology of Mesenchymal Stem Cell Migration to Tumors, Biomedical Engineering Society Annual Meeting (MD, Podium Presentation). 37. McGrail D, Ghosh D, Dawson M (2010). Tumor-Secreted Soluble Proteins Mediate Mesenchymal Stem Cell Migration to Tumors by Rapidly Changing Cytoskeletal Rigidity, American Institute of Chemical Engineers Annual Meeting (DG, Podium Presentation). 38. McGrail D, Dawson M (2010). Probing the Microrheology of Mesenchymal Stem Cell Migration to Tumors, Biophys. J. Supplement (MD, Poster Presentation). 39. McGrail D, Dawson M (2009). Effect of Tumor Secreted Soluble Factors On Mesenchymal Stem Cell Microrheology and Heterogeneity, American Institute of Chemical Engineers Annual Meeting (DM, Poster Presentation). 40. Tang B, Dawson M, Lai S, Wang YY, Suk, JS, Yang M, Zeitlin P, Boyle M, Fu J, Hanes J (2009). Biodegradable polymer nanoparticles that rapidly penetrate the mucus barrier and their efficacy in a mouse model of human lung cancer, Japan Symposium on Drug Delivery Systems. 41. Perentes J, McKee T, Ley C, Mathiew H, Dawson M, Padera T, Munn L, Jain R, Boucher Y (2008). In vivo imaging of tumor associated fibroblast interaction with collagen fibers reveals a novel mechanism of extracellular matrix remodeling in tumors. Cancer Research 68 (9): 4204. 42. Tang B, Dawson M, Lai S, Wang Y, Yang M, Fu J, Watkins N and Hanes J (2008). Polymer Nanoparticles That Overcome the Mucus Barrier and Their Efficacy In a Mouse Model of Human Lung Cancer, American Institute of Chemical Engineers Annual Meeting (BT, Poster Presentation). 43. Huang P, Dawson M, Lanning R, Jain RK, and Fukumura D (2008). Preliminary Study of Spontaneous Tumors in VEGF-GFP/FVB and Tie2-GFP/FVB Transgenic Mice. American Association for Laboratory Animal Science. JAALAS 47(5): 170. 44. Duda D, Jones R, Dawson M, Capen D, Tyrrell A, Fukumura D, Jain R (2008). Phenotypic and functional characterization of proangiogenic monocytes. FASEB 22 (1): 238.7. 45. Dawson M, Duda D, Jain R (2007). Engineering Drug, Gene, and Cell-Based Delivery Systems for the Treatment of Human Disease, American Institute of Chemical Engineers Annual Meeting (MD, poster presentation). 46. Dawson M, Duda D, Jain R (2007). Quantitative Analysis of the Effects of VEGFR1- Signaling on Bone Marrow-Derived Cell Recruitment and Accumulation in Lung Metastases, American Institute of Chemical Engineers Annual Meeting (MD, podium presentation).

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47. Tang B, Dawson M, Fu J, Watkins N, Hanes J (2007). In Vitro and In Vivo Evaluation of Poly (ether-anhydride) Particles for Potential Treatment of Lung Cancer. Controlled Release Society (BT, Podium Presentation). 48. Dawson M, Duda D, Jain R (2006). The Role of Mesenchymal Bone Marrow-derived Cells in Tumor Formation, Cell Res 295, 395-406 (MD, Podium Presentation). 49. Dawson M, Duda D, Jain R (2006). The Role of Mesenchymal Bone Marrow-derived Cells in Tumor Formation, American Institute of Chemical Engineers Annual Meeting (MD, Podium Presentation). 50. Dawson M, Duda D, Jain R (2006). The Role of Mesenchymal Bone Marrow-derived Cells in Tumor Formation, Conference of Ford Fellows, Academic Exchange (MD, Podium Presentation). 51. Dawson M, Wirtz D, Hanes J (2004). Microscopic Viscoelasticity of CF Sputum Determined by High-Resolution Nanoparticle Tracking, American Institute of Chemical Engineers Annual Meeting (MD, Podium Presentation). 52. Dawson M, Wirtz D, Hanes J (2004). Gene Carriers Modified w/PEG Demonstrate Increased Transport and Stability in Mucus as Explored with High-Resolution Nanoparticle Tracking, American Institute of Chemical Engineers Annual Meeting (MD, Podium Presentation). 53. Dawson M, Wirtz D, Hanes J (2004). Real-time tracking of nanoparticle gene carriers in gastrointestinal mucus, Biophysical Society Annual Meeting (MD, Poster Presentation). Cited in Advanced Drug Delivery Reviews. 54. Dawson M, Krauland E, Wirtz D, and Hanes J (2004). Transport of Cationic Particle Gene Carriers in Gastric Mucus, Proceedings of the International Symposium on Controlled Release of Bioactive Materials. Controlled Release Society (MD, Podium Presentation). 55. Dawson M, Wirtz D, and Hanes J (2004). The Effects of Mucolytic Agents on Transport Rates of Nanoparticles in Human CF Sputum, Proceedings of the International Symposium on Controlled Release of Bioactive Materials. Controlled Release Society (MD, Poster Presentation). 56. Dawson M, Wirtz D, and Hanes J (2003). Transport Phenomena and Microrheology in Human Cystic Fibrotic Mucus by Real-Time Nanoparticle Tracking, Proceedings of the International Symposium on Controlled Release of Bioactive Materials. Controlled Release Society (MD, Podium Presentation). 57. Dawson M, Wirtz D, Hanes J (2003). Effects of rhDNase Therapy on the Microrheological Properties and Transport Rates of Nanoparticles in Cystic Fibrotic Mucus as Probed by Multiple Particle Tracking and Confocal Microscopy, American Institute of Chemical Engineers Annual Meeting (MD, Podium Presentation). 58. Dawson M, Wirtz D, Hanes J (2003). Individual Gene Carrier Transport Phenomena in Human Cystic Fibrosis Sputum Treated with rhDNase. Biomedical Engineering Society Annual Meeting (MD, Poster Presentation). 59. Dawson M, Wirtz D, Hanes J (2003). Nanoparticle Transport in Cystic Fibrosis (CF) Mucus by Multiple Particle Tracking (MPT), International Society of Aerosols in Medicine (MD, Podium and poster presentations).

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60. Dawson M, Wirtz D, Hanes J (2003). Real-time Multiple Particle Tracking of Gene Carriers in Cystic Fibrotic Sputum. American Society of Gene and Cell Therapy. Molecular Therapy 7(5) S373-S374. (MD, Podium and poster presentations). Cited in Mucins. 61. Dawson M, Wirtz D, and Hanes J (2003). Dynamics of gene carrier transport in synthetic and cystic fibrosis mucus as explored by multiple particle tracking and rheology, Biophysical Society Annual Meeting (MD, Poster Presentation). 62. Dawson M, Wirtz D, Hanes J (2002). Mucosal Barriers to Drug and Gene Delivery in the Lung Explored with Nanoparticle Tracking, American Institute of Chemical Engineers Annual Meeting (MD, Podium Presentation).

Abstracts (Local Meetings)

1. Pena CM, Dawson M (2018). Development of a novel 3D organoid model to study epithelial ovarian cancer growth and matrix invasion. Molecular Biology, Cell Biology, and Biochemistry, Brown University. 2. Hsu J, Pena CM, Lee A, Quach N, Ghosh D, Dawson M (2018). Characterizing Putative Epithelial-to-Mesenchymal Transition Phenotype of Ovarian Cancer Spheroids in Three- Dimensional Hydrogel Scaffolds. Brown Summer Research Symposium, Brown University. 3. Gibbs S, Quach N, Dawson M (2018). Enhancing Therapeutic Efficacy of Platinum Based Drugs by Pharmacologically Inhibiting PARP in Ovarian Cancer. Brown Summer Research Symposium, Brown University. 4. Pena CM, Dawson M (2017). Pathways to Chemoresistant Ovarian Cancer: Microenvironmental Regulation of FAK-Based Adhesion. Molecular Biology, Cell Biology, and Biochemistry, Brown University. 5. Clifton E, Xuan B, Ghosh D, Dawson M (2017). SASP-induced polyploidy and nuclear enlargement: a potential system of chemotherapeutic resistance. Brown Summer Research Symposium, Brown University. 6. Soriano K, Ghosh D, Dawson M (2017). Effects of Substrate Elasticity on Malignancy and Chemotherapeutic Resistance. Brown Summer Research Symposium, Brown University. 7. Skipper T, Ghosh D, Dawson M (2017). Alginate hydrogels for 3-D cell culture applications. Brown Summer Research Symposium, Brown University. 8. Acero S, Ghosh D, Dawson M (2017). Mechanosensitivity analysis of breast cancer tumor cells from needle biopsy. Brown Summer Research Symposium, Brown University. 9. Xuan B, Ghosh D, Dawson M (2017). Investigating the Effect of the Senescence Associated Secretory Phenotype on Tumor Progression. First Year Molecular Pharmacology and Physiology Talks, Brown University. 10. McGrail D, Dawson M (2015). Ovarian Cancer Resistance to Microtubule-Targeting Chemotherapeutics is Controlled by Changes in Cell Adhesion. Podium, Georgia Tech Career, Research, and Innovation Development Conference. 11. McAndrews K, Yi J, Dawson M (2015). Enhanced Engraftment of Stromal Cells in More Malignant Tumors. Podium presentation, Georgia Tech Chemical and Biomolecular Engineering Graduate Research Symposium.

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12. McAndrews K, Yi J, Dawson M (2015). Differential Adhesion of Stromal Cells to Malignant and Metastatic Cancer Cells. Poster presentation, Georgia Tech Career, Research, and Innovation Development Conference. 13. McAndrews K, Kim M, Lam T, McGrail D, Dawson M (2014). Architectural and Mechanical Cues Direct Mesenchymal Stem Cell Function on Cross-Linked Gelatin Scaffolds. Georgia Tech Chemical and Biomolecular Engineering Graduate Research Symposium, Atlanta, GA (KM, Podium Presentation). 14. Ghosh D, McGrail D, McAndrews K, Dawson M (2014). Biophysical Approaches for Investigating Stem Cell Behavior in Complex Environments. 17th Annual Hilton Head Workshop on Regenerative Medicine: Technologies Enabling Novel Therapies, Hilton Head, SC (MD, Podium Presentation). 15. Khambhati N, Patel K, Qi M, McGrail D, Dawson M (2014). Elucidating Alternative Mechanisms and Consequences of Resistance to Chemotherapeutics. Air Products Symposium (NK, Honorable Mention in Poster Presentation). 16. Patel K, Khambhati N, Qi M, McGrail D, Dawson M (2014). Taxol Resistance Alters Ovarian Cancer Cell Adhesion Kinetics and Strength. UROP Spring Symposium (KP, Poster Presentation). 17. Kieu Q, McGrail D, Dawson M (2014). Enhancement of Ovarian Cancer Malignancies due to Low Rigidity Matrix. Air Products Symposium (QK, Poster Presentation). 18. Kieu Q, McGrail D, Dawson M (2014). Correlation between Epithelial-Mesenchymal Transition and Mechanical Changes in Breast Cancer Cells. UROP Spring Symposium (QK, Poster Presentation). 19. McGrail D, Dawson M (2014). Ovarian Cancer Metastatic Tropism is Controlled by Matrix Rigidity. Georgia Tech Chemical and Biomolecular Engineering Graduate Research Symposium (DM, Podium Presentation). 20. McGrail D, Dawson M (2014). Metastatic Ovarian Cancer Tropism is Regulated through a Mechanosensitive Rho/ROCK Pathway. GTRIC Symposium (DM, Poster Presentation). 21. McAndrews K, Dawson M (2013). Role of Stromal Cell Crosstalk and Matrix Rigidity in Cancer Progression, Georgia Tech Chemical and Biomolecular Engineering 4th Year Colloquium, Georgia Institute of Technology (KM, Podium Presentation). 22. Trang V, McAndrews K, Dawson M (2013). Role of SDF-1-CXCR4 Axis on the Mobility of Mesenchymal Stem Cells. UROP Spring Symposium, Georgia Institute of Technology (VT, Poster Presentation). 23. Iandoli J, Kieu Q, McGrail D, Dawson M (2013). Effects of Substrate Rigidity on Metastatic Cancer Cell Adhesion, UROP Spring Symposium. 24. Kim M, Lam T, McAndrews K, Ghosh D, McGrail D, Dawson M (2013). Engineering Gelatin Scaffold Mechanics for Tissue Engineering Applications. UROP Spring Symposium, Georgia Institute of Technology (MK and TL, Poster Presentation). 25. McAndrews K, McGrail D, Dawson M (2012). Culture-associated Mechanical Changes of Human Mesenchymal Stem Cells, Graduate and Postdoc Seminar Series, Georgia Institute of Technology (KM, Podium Presentation). 26. Kuo C, Ghosh D, Dawson M (2012). Gelatin Scaffolds for Tissue Engineering Applications, Air Products Symposium (CK, 3rd Place in Poster Presentation).

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27. Quach N, McAndrews K, McGrail D, Dawson M (2012). Understanding the Role of Soluble Growth Factors and Substrate Rigidity on Human Mesenchymal Stem Cell Osteogenesis. UROP Spring Symposium (NQ, Poster Presentation). 28. McGrail D, Dawson M (2011). Designing Stem Cell-Based Therapeutics and Other Unintended Consequences of Research, Undergraduate Research Kaleidoscope (DM, Interview). 29. McGrail D, Dawson M (2011). Mesenchymal Stem Cell Mechanical Priming Increases Accumulation in Murine Mammary Tumors, Air Products Research Symposium (DM, Poster Presentation). 30. McGrail D, Dawson M (2010). Investigation of Motile Mesenchymal Stem Cell Biophysical Response to Soluble Tumor Secreted Soluble Factors, UROP Spring Symposium (DM, Poster Presentation). 31. McGrail D, Dawson M (2010). Mesenchymal Stem Cell Mechanical Response and Migration Optimization to Tumor Secreted Proteins, ACC Meeting of the Minds (DM, Poster and Podium Presentations). 32. McGrail D, Dawson M (2010). Response of Mesenchymal Stem Cells to Tumor Secreted Soluble Factors, Air Products Research Symposium (DM, 3rd Place in Poster Presentation). 33. McGrail D, Dawson M (2009). Cytoskeletal Response of Mesenchymal Stem Cells to Tumor Secreted Soluble Factors, Festival of Research Ideas in Cancer Biology and Technology (DM, Poster Presentation). 34. McGrail D, Dawson M (2009). Probing the Microrheology of Mesenchymal Stem Cell- Based Therapeutics, Georgia Cancer Coalition 2009 Symposium (MD, Podium Presentation).

Other Publications and Creative Products

1. Press Release, Article featured in Brown Medicine, Brown Daily Herald, BioPortfolio, EurekAltert, R&D, Science Daily, Long Room, Drug Discovery and Development, Medical News, and so forth, Article titled, “Dysregulation in Actin Cytoskeletal Organization Drives Increased Stiffness and Migratory Persistence in Polyploidal Giant Cancer Cells.” August 9, 2018. 2. Press Release, Article featured on BioPortfolio. Article titled, “Enhanced Adhesion of Stromal Cells to Invasive Cancer Cells Regulated by Cadherin 11.” June 9, 2015. 3. Press Release, Feature article highlighted in Medicalphysicsweb, IOP Science, Medscape, Bioportfolio, among others. Press release on our article titled, “Tumour metastasis: environment matters.” March 30, 2015. 4. Press Release, Research featured on Georgia Tech Research Horizons, MedicalXpress, among others. Article titled, “SNAIL-induced epithelial-to-mesenchymal transition produces concerted biophysical changes from altered cytoskeletal gene expression.” December 17, 2014. 5. Video, Direct to Discovery K12 Outreach Video presented by Dawson, M. Research profile. http://www.directtodiscovery.org/videodawson.html.

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6. Video, Direct to Discovery K12 Outreach Video presented by Dawson, M to high school physiology and anatomy classes led by Christine Rhyoo and Cris Cook. Cell mechanics module. http://www.d2dportal.org/resource/cook-rhyoo-dawson-spring-2013-session-1. 7. Video, Direct to Discovery K12 Outreach Video presented by Dawson, M to high school physiology and anatomy classes led by Christine Rhyoo and Cris Cook. Hallmarks of Cancer module. http://www.d2dportal.org/resource/cook-rhyoo-dawson-d2d-session-1- fall-2013. 8. Feature article in Journal of Cell Science: In this Issue – Mechanical Cues in Metastatic Ovarian Cancer Cells. June 15, 2014 (J. Cell Sci. 127, e1201). 9. Press Release, Research featured on Science Daily, National Science Foundation News from the Field, Science Newsline Medicine, and others. Article was titled, “Ovarian Cancer Cells More Aggressive on Soft Tissues.” May 8, 2014. 10. Highlighted in GT Faces of Inclusive Excellence (2013). 11. Audio File, Inside the Black Box, Pete Ludovice Interviews Michelle Dawson. Title: Cancer, Beyond the Cells. December 5, 2012. https://smartech.gatech.edu/handle/1853/46861 12. Video, Bone Marrow and Cancer. IBB Faculty Profile. June 5, 2009. https://smartech.gatech.edu/handle/1853/30164 13. Press Release, Michelle Dawson receives a Cancer Research Award from the Georgia Cancer Coalition (2009). http://www.gatech.edu/newsroom/release.html?id=2539&source=1 http://www.georgiacancer.org/res-cancerfundawardees0809.php 14. Guest coach, Exxon Mobil Success Program Women’s Basketball, Pink Zone Breast Cancer Awareness Game, February 8, 2009.

External presentations

1. Invited talk, University of Rhode Island, Amgen Seminar Series in Chemical Engineering, West Greenwich, RI. Tumor Micorenvironment Interactions: Forcing Cancer Progression. February 22, 2018. 2. Invited participant, UC San Diego NSF INCLUDES Conference, San Diego, CA. Collective Impact as a Pathway to Reinvigorate Broadening Participation in STEM, January 20-22, 2017. 3. Invited talk, 2016 Engineering Conference International (ECI), Vienna, Austria. Conference Theme: Nanotechnology in Medicine - From Molecules to Humans. Session 6: Nanostructures for Cell Adhesion, Growth, Motility, and Differentiation. Modeling the Tumor Microenvironment with Nanostructured Materials. July 7, 2016. 4. Invited talk, West Virginia University, Chemical Engineering, Morgantown, WV. Mechanics and Malignancy: Biophysical Approaches for Understanding Cancer. March 23, 2016. 5. Invited talk, Brown University, Biomedical Engineering Seminar, Providence, RI. Mechanics and Malignancy: Biophysical Approaches for Understanding Cancer. March 18, 2016.

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6. Invited talk, University of Buffalo, Biomedical Engineering, Buffalo, NY. Mechanics and Malignancy: Biophysical Approaches for Understanding Cancer. February 17, 2016. 7. Invited talk, Colorado State University, Mechanical Engineering, Fort Collins, CO. Mechanics and Malignancy: Biophysical Approaches for Understanding Cancer. February 10, 2016. 8. Invited talk, McGill University, Bioengineering, Montreal, Canada. Mechanics and Malignancy: Biophysical Approaches for Understanding Cancer. January 20, 2016. 9. Invited talk, University of Arizona, Biomedical Engineering, Tucson, AZ. Mechanics and Malignancy: Biophysical Approaches for Understanding Cancer. November 15, 2015. 10. Invited talk, University of Delaware, Biomedical Engineering, Newark, DE. Mechanics and Malignancy: Biophysical Approaches for Understanding Cancer. October 5, 2015. 11. Invited talk, Louisiana Tech University, Frontiers in Biomedical Engineering, Ruston, LA. Mechanics and Malignancy: Biophysical Approaches for Understanding Cancer. September 21, 2015. 12. Invited talk, University of Delaware, Biomedical Engineering, Newark, DE. Mechanics and Malignancy: Utilizing Biophysical Approaches to Understand the Tumor Microenvironment. October 5, 2015. 13. Invited talk, Colorado State University, Chemical and Biological Engineering, Fort Collins, CO. Biophysical Approaches for Investigating the Tumor Microenvironment. May 15, 2015. 14. Invited talk, University of Georgia, College of Pharmacy, Department of Pharmaceutical Sciences, Athens, GA. High-Content Biophysical Screening for Identification of Aggressive and Chemoresistant Cancer and Stromal Cells. February 25, 2015. 15. Invited talk, 2015 Annual Biomedical Engineering Cell and Molecular Bioengineering Conference (CMBE), St Thomas, US Virgin Islands. Conference theme: from Womb to Tomb: Mechanobiology of Generation, Regeneration, and Degeneration. Manipulating Cancer Cell Mechanics to Reduce Metastasis. January 10, 2015. 16. Invited talk, Kennesaw State University, Department of Biology and Physics, Molecular Biosciences Interest Group, Kennesaw, GA. Mechanics and Malignancy: Biophysical Approaches for Investigating the Tumor Microenvironment. September 5, 2014. 17. Invited talk, 2014 World Congress in Biomechanics, Boston, MA. Lymphatics and interstitial fluid: Biomechanics and Modeling. Inverse Mechanical Tropism of Metastatic Ovarian Cancer Cells. July 10, 2014. 18. Invited talk, Celebration of Data Symposium (in honor of Denis Wirtz being appointed as Vice Provost for Research at Johns Hopkins University), Baltimore, MD. Manipulating Cancer Cell Mechanics to Reduce Metastasis. June 20, 2014. 19. Plenary presentation, Hilton Head Regenerative Medicine Workshop. Biophysical Approaches for Investigating Stem Cell Behavior in Complex Environments. March 29, 2014. 20. Invited talk, 80th Annual Meeting of the Applied Physics Society (APS): Cellular Mechanics and Biomechanics session, Bowling Green, KY. Mechanics and Malignancy: Biophysical Approaches for Investigating the Tumor Microenvironment. November 22, 2013.

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21. Invited talk, Johns Hopkins University, School of Chemical and Biomolecular Engineering Seminar, Baltimore, MD. Mechanics and Malignancy: Biophysical Approaches for Investigating the Tumor Microenvironment. November 14, 2013. 22. Invited talk, Johns Hopkins School of Medicine, Center for Nanomedicine. Mechanics and Malignancy: Biophysical Approaches for Investigating the Tumor Microenvironment. November 15, 2013. 23. Invited talk, University of California San Diego, Department of Bioengineering Seminar. Biomechanical Interactions of Stem Cells and Cancer Cells in the Tumor Microenvironment. October 11, 2013. 24. Plenary presentation (selected by submitted abstract), Presentations by the Fellows. Conference of the Ford Fellows 2013, National Academy of Sciences, Washington, DC. Mechanical Transformations and Cancer Progression: Biophysical Approaches to Probing Tumor Microenvironments. September 28, 2013. 25. Invited talk, University North Carolina Charlotte, Department of Chemistry. Engineering Mesenchymal Stem Cell Based Gene Delivery Systems. Nanoscale Science Seminar Series, February 2, 2012. 26. Invited talk, Emory University School of Medicine, Cardiovascular Biology Seminar. Engineering Mesenchymal Stem Cell Based Gene Delivery Systems, February 21, 2011. 27. Invited talk, Emory University School of Medicine, Molecular Pathways and Biomarker Program, Winship Cancer Institute, Bone Marrow Cell Migration to Tumors: A Critical Step in Tumor Growth and Metastasis. March 2010. 28. Invited talk, Emory University School of Medicine, Breast Cancer Radiation Research Meeting, Winship Cancer Institute. Bone Marrow Cell Migration to Tumors: A Critical Step in Tumor Growth and Metastasis. July 15, 2009. 29. Invited talk, Clark Atlanta University, Department of Biological Sciences. The Role of Bone Marrow Derived Cells in Tumor Growth and Metastasis. February 27, 2009. 30. Plenary presentation (selected by submitted abstract), Presentations by the Fellows. Conference of the Ford Fellows 2007, Beckman Center of the National Academies, Irvine, CA. Infiltration of Bone Marrow Derived Cells into Tumors: A Critical Step in Tumor Growth and Metastasis, September 25, 2007. 31. Invited talk, American Institute of Chemical Engineers Mid-Atlantic Divisional Meeting, Baltimore, MD. Nanoparticle Transport through Mucus Barriers (2004). 32. Invited talk, The Johns Hopkins University School of Medicine, Department of Physiology, Baltimore, MD. Real-Time Nanoparticle Transport in Cystic Fibrosis and Synthetic Sputum (2003).

Internal presentations

1. Invited talk, Stem Jazz, Tumor Microenvironment Interactions: Stromal Cell Aging and Breast Cancer Progression. December 6, 2018. 2. Invited talk, 2018 MCB Fall Seminar Series, Tumor Micoenvironment Interactions: Forcing Cancer Progression. November 28, 2018. 3. Invited talk, BIOL 0100 Guest Speaker, Biophysics of Polyploidal Giant Cancer Cells, November 1, 2018.

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4. Research overview, 2018 Molecular Cell Biology Faculty on Parade, Using Single Cell Biophysics to Understand Cancer. October 4, 2018. 5. Research overview, 2018 Molecular Pharmacology and Physiology Breakfast Talk, Dawson Cell Biophysics Lab. October 24, 2018. 6. Invited talk, 2018 Women & Infants Pathology Department Seminar, Tumor Microenvironment Interactions: Forcing Cancer Progression. March 27, 2018. 7. Invited talk, 2018 Ovarian Cancer Research Group Seminar (working group includes researchers and clinicians from Brown University, Rhode Island Hospital, and Women & Infants Hospital), Tumor Microenvironment Interactions: Forcing Cancer Progression. February 26, 2018. 8. Invited talk, 2018 MCB Fall Seminar Series, Tumor Micoenvironment Interactions: Forcing Cancer Progression. November 28, 2018. 9. Research overview, 2017 Molecular Cell Biology Faculty on Parade, Using Single Cell Biophysics to Understand Cancer. October 24, 2017. 10. Research overview, 2017 Molecular Pharmacology and Physiology Breakfast Talk, Dawson Cell Biophysics Lab. September 19, 2017. 11. Invited talk, 2017 Biology of Aging Retreat, Biophysics of Giant Polyploidal Cancer Cells in an Aging Stroma, November 4, 2017. 12. Invited talk, 2017 Graduate Students of Color Orientation, Focusing Your Professional Activities to Build a Strong CV, August 28, 2017. 13. Invited talk, 2017 Molecular Pharmacology and Physiology Graduate Program Retreat, Biophysics of Cancer Progression. May 3, 2017. 14. Research overview, 2016 Molecular Cell Biology Faculty on Parade, Using Single Cell Biophysics to Direct Therapy. October 25, 2016. 15. Invited talk, 2016 BME Fall Seminar Series, Mechanics and Malignancy: Biophysics of Cancer. October 27, 2016. 16. Invited talk, 2016 Rhode Island Hospital Orthopaedics Research Seminar, Using Single Cell Biophysical Analysis to Understand Cancer. October 26, 2016. 17. Invited talk, 2016 MMI Fall Seminar Series, Mechanics and Malignancy: Biophysical Approach to Understanding Cancer. September 29, 2016. 18. Invited talk, 2016 MCB Fall Seminar Series, Using Single Cell Biophysics to Understand Cancer. September 28, 2016. 19. Invited talk, 2016 Rhode Island Hospital Pathology Seminar Series, Using Single Cell Biophysics to Understand Cancer. September 27, 2016. 20. Research overview, 2016 Pathobiology Faculty on Parade, Dawson Cell Biophysics and Engineering Lab. September 21, 2016. 21. Research overview, 2016 Molecular Pharmacology and Physiology Breakfast Talk, Dawson Cell Biophysics and Engineering Lab. September 14, 2016. 22. Invited talk, Integrated Cancer Research Seminar Series, Georgia Institute of Technology. Mechanics and Malignancy: Biophysical Approaches for Investigating the Tumor Microenvironment. On day presentation, fall semester, 2013-2015. 23. Invited talk, Georgia Tech SURE Program Seminar Series, Biophysical Approaches to Predicting Cell Behavior. June 13, 2013.

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24. Invited talk, Georgia Tech (GT) 1000 Chemical & Biomolecular Engineering Lecture, Biophysical Approaches to Predicting Cell Behavior, GT 1000 Chemical & Biomolecular Engineering Lecture. November 27, 2012. 25. Panel participant, Georgia Tech Freshman Reading Panel on Ethics, Immortal Life of Henrietta Lacks. November 5, 2012. 26. Invited talk, Georgia Tech GIFT K12 Program Seminar Series, Dawson Stem Cell Biophysics and Engineering Lab. June 17, 2011. 27. Invited talk, Georgia Tech and Emory Center for Regenerative Medicine Winter Retreat. Engineering Mesenchymal Stem Cells for more Rapid Wound Healing, January 26, 2011. 28. Invited talk, Georgia Tech IBB Industrial Partner’s Symposium, Regenerative Medicine Session. Engineering Mesenchymal Stem Cell Based Gene Delivery Systems, October 21, 2010. 29. Invited talk, Georgia Tech ME 3141, Cutting Edge Lecture Series: Engineering Mesenchymal Stem Cell Based Gene Delivery Systems. September 9, 2010. 30. Invited talk, IBB Breakfast Club Seminar Series, Engineering Mesenchymal Stem Cell Based Gene Delivery Systems. August 10, 2010. 31. Invited talk, Georgia Tech School of Biology Seminar Series, Bone Marrow Cell Migration to Tumors: A Critical Step in Tumor Growth and Metastasis (2010). 32. Invited talk, Georgia Tech SURE Program Seminar Series, Probing the Mechanical Properties of Bone Marrow Derived Cells that Migrate to Tumors. July 2010. 33. Invited talk, Exxon Mobil Success Program, Georgia Institute of Technology. Building My Bioresearch Toolbox. December 2008.

Other Scholarly and Creative Accomplishments

US Patent: Hanes J, Dawson M, Wirtz D, Fu J, Krauland E, Drugs and gene carrier particles that rapidly move through mucus barriers. Application number 10,587,512 (submitted in 2005). Patent Number 8,957,034 (finalized in 2015).

Honors and Awards

American Association for Cancer Research Minority and Minority Serving Institution Faculty Scholar in Cancer Research Award, 2018 Women in Engineering (WIE) Teaching Excellence Award, 2013 Georgia Tech Junior Faculty Outstanding Undergraduate Research Mentor Award, 2013 Georgia Cancer Coalition Breast Cancer Research Award, 2009 Carl Storm Minority Fellowship for Gordon Research Conference Attendance, 2007 Ford Foundation Postdoctoral Minority Fellowship, 2006 CRS-Capsugel/Pfizer Innovative Aspects of Oral Drug Delivery Award, 2004 Science and Engineering Education Scholars Program Travel Award, 2004 Biophysical Society FASEB MARC Travel Award, 2003 International Society for Aerosol Medicine Student Research Award, 2003 Achievement Rewards for College Students Fellowship, 2000-01 Ford Foundation Predoctoral Minority Fellowship, 2001-04

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National Science Foundation Graduate Research Fellowship, 2001-05 Louisiana Tech Biomedical Engineering Outstanding Senior Award, 1999

Grants and Contracts

Project Title: BMMB: Investigating the Biophysics of Giant Polyploidal Cancer Cells in an Aging Tumor Stroma (1825174) Funding Source: National Science Foundation Total Funding Awarded and For Your Portion of the Project: $350,000, Role: PI Period of Contract: 08/15/18-07/31/21, Candidate’s Share: 100%

Project Title: Development of a 3D Organoid Culture Model to Identify Drivers of Cancer Progression Funding Source: OVPR Grant Resubmission Funds (for NSF resubmission to EBMS) Total Funding Awarded and For Your Portion of the Project: $15,000, Role: PI Period of Contract: 08/1/18-08/1/19, Candidate’s Share: 100%

Project Title: Molecular and Mechanical Regulators of the Metastatic Niche and Ovarian Cancer Metastasis (005756) Funding Source: COBRE, Lifespan Center for Cancer Research Development Total Funding Awarded and For Your Portion of the Project: $50,000, Role: PI Period of Contract: 10/1/2017 – 6/30/2018, Candidate’s Share: 100%

Project Title: Using Single Cell Biophysics and Shear Wave Ultrasound Elastography to Measure Cancer Mechanics Across Multiple Length Scales Funding Source: Research Seed Funds, Office of Vice President for Research, Brown University Total Funding Awarded and For Your Portion of the Project: $50,000/$25,000, Role: Co-PI Period of Contract: 1/26/2017 – 6/30/2018, Candidate’s Share: 50%

Project Title: Toward the Development of Molecular Therapeutics for Uterine Leiomyoma: 3D Mechanical Culture Models for Dissecting the Molecular Signaling Pathways Mediating Fibroid Growth and Development Funding Source: GTEC (seed grant) Total Funding Awarded and For Your Portion of the Project: $70,000/$35,000, Role: Co-PI Period of Contract: 10/1/2014-6/30/2015, Candidate’s Share: 50%

Project Title: Direct-to-Discover Race to the Top K12 Outreach Grant (1411304) Funding Source: State of Georgia Total Funding Awarded and For Your Portion of the Project: $1,500,000/$40,000 Role: Senior Personnel, Collaborators: Barrow County Schools and GTRI Period of Contract: 9/1/2012-6/30/2014, Candidate’s Share: ~3%

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Project Title: CBET - Engineering Mesenchymal Stem Cells for More Rapid Wound Healing (1066585) Funding Source: National Science Foundation Total Funding Awarded and For Your Portion of the Project: $298,850 Role: PI, Period of Contract: 7/15/2011 – 8/1/2014, Candidate’s Share: 100%

Project Title: Anti-Angiogenic Mesenchymal Stem Cell-Based Therapy for Metastatic Melanoma (1411304) Funding Source: GTEC (seed grant) Total Funding Awarded and For Your Portion of the Project: $30,000 Role: PI, Period of Contract: 9/1/2012-6/30/2013, Candidate’s Share: 100%

Project Title: Engineering Mesenchymal Stem Cells for More Rapid Wound Healing (2731318) Funding Source: GTEC (seed grant) Total Funding Awarded and For Your Portion of the Project: $35,000 Role: PI, Period of Contract: 8/16/2010-6/30/2011, Candidate’s Share: 100%

Project Title: BRIGE - Understanding the Mechanical Properties of Migrating Mesenchymal Stem Cells (1032527) Funding Source: National Science Foundation Total Funding Awarded and For Your Portion of the Project: $174,990 Role: PI, Period of Contract: 9/1/2010-8/31/2012, Candidate’s Share: 100%

Project Title: Mesenchymal Stem Cell-Based Therapeutics for the Treatment of Breast Cancer (110257) Funding Source: Georgia Cancer Coalition Total Funding for My Portion of the Project: $50,000 Role: PI, Period of Contract: 2/1/2009 – 2/1/2010, Candidate’s Share: 100%

SOCIETAL AND POLICY IMPACTS

1. K12 Outreach at Brown University: Presented research to 30 advanced 12th grade science students from science cooperative in upstate New York. The program title is Questar III New Visions Medical Program. Title of presentation: “Biophysics and Medicine.” Follow-up activities developed through D2D (described below) were shared with the teachers. The presentation was held at Brown University on December 16, 2016. 2. GT-Direct to Discovery (D2D): Through D2D the Dawson lab shared cutting edge research with K-12 students in Georgia and beyond using a series of D2D modules, including pre- lecture materials, interactive videoconference lectures, and follow-up hands-on activities, related to cellular engineering concepts. D2D partnerships included: Thomasville High School Physics, Ireland Music and Science Program, Ware County Schools, DeKalb County Middle School Afterschool Science Program, D2D Collaboration and Splash Days, Cobb County Biology Classes, and Barrow County Schools (primarily Anatomy, Physiology, and Biology). 3. GT High school internships: Exceptional high school students, identified through AP science classes at local schools, including Wheeler High School and Dunwoody High School,

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were given the opportunity to complete 10-week internships in my GT lab. Students were given small supervised cell mechanics projects with goals that linked to the D2D program. 4. GT On-Campus partnerships with high school teachers: (1) Jennifer Hager, Cobb County high school genetics teacher, 2010-2011, K-12 Outreach Partner for Wheeler High School Summer AP Genetics Program and (2) Cris Cook and Christine Rhyoo, Barrow County high school science teachers, NSF GIFT teachers (worked in my lab for 1 month during Summer 2012), Barrow County D2D Partners for anatomy/physiology courses (2011-2013). 5. GT K12 Outreach Off-Campus: Presented research to 9th grade science classes (6 classes in all) at the Galloway School. Title of presentation: “Mechanics and Malignancy: Biophysical Approaches for Investigating Cell Behavior.” May 16, 2014.

TEACHIKNG

1. BIOL 0810: Applied Cell and Molecular Biology (Brown University) Spring 2019, 13 students are registered. 2. BIOL 0810: Applied Cell and Molecular Biology (Brown University) Spring 2018, 2 students registered and 1 audited. 3. ChBE 3210 Transport II: Heat and Mass Transfer (Georgia Tech) Summer 2014, 42 students Summer 2013, 25 students Fall 2012, 33 students Summer 2012, 16 students Spring 2012, 36 students Fall 2011, 41 students Summer 2011, 26 students Fall 2010, 37 students Summer 2010, 29 students Fall 2009, 26 students Summer 2009, 27 students Spring 2009, 60 students 4. ChBE 4803, Biomolecular Engineering of the Cell (Georgia Tech) Fall 2015, 57 students Fall 2013, 38 students Spring 2011, 16 students 5. ChBE 3200 Transport I: Fluid Mechanics (Georgia Tech) Spring 2013, 35 students Spring 2015, 87 students

MENTORING

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Graduate Students, Brown University 1. Botai Xuan, PhD student Department: Molecular Pharmacology, Physiology, and Biotechnology Third year PhD candidate Project: Polyploidal Giant Breast Cancer Cells that Drive Paclitaxel Resistance 2. Carolina Mejia Pena, PhD student Department: Molecular Biology, Cell Biology, and Biochemistry Third year PhD candidate (NSF fellow) Project: Role of FAK in Chemoresistant Ovarian Cancer 3. Amy Lee, PhD student Department: Biomedical Engineering Second year PhD student Project: Exosome-Mediated Interactions in Ovarian Cancer Metastasis 4. Sorel Ouonkap Yimga, PhD rotation student Department: Molecular Biology, Cell Biology, and Biochemistry Rotation student (Presidential Fellow) Project: Biophysics of Polyploidal Giant Cancer Cells in Ovarian Cancer 5. Aakash Jhaveri, ScM student Department: Biotechnology First year ScM student Project: Nuclear Biophysics to Understand Radiation Resistant Prostate Cancer 6. Jiwon Seo, PhD rotation student Department: Molecular Biology, Cell Biology, and Biochemistry Rotation Student (no longer working in my lab) Project: Using Biophysical Models to Understand Chemoresistant Ovarian Cancer 7. Blessing Akobundu, PhD student Department: Molecular Pharmacology, Physiology, and Biotechnology Rotation student (no longer working in my lab) Project: Stromal Cell Interactions in Radiation Resistant Prostate Cancer 8. Chyna Gray, PhD rotation student Department: Molecular Biology, Cell Biology, and Biochemistry Rotation student (no longer working in my lab) Project: Cancer Treatment Resistance and Elements of the Tumor Microenvironment 9. Aida Berhane, MS student Department: Biomedical Engineering First year MS student (no longer working in my lab) Project: Using Single Cell Biophysics to Measure Breast Cancer Cell Mechanics 10. Zhan Wu, MS student Department: Biomedical Engineering First year MS student (no longer working in my lab) Project: Using Single Cell Biophysics to Predict Breast Cancer Drug Response

Undergraduate Students, Brown University

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1. Blas Lezcano, Biomedical Engineering, Graduated May 2019. Independent research Fall 2016. 2. Oksana Goretaya, Chemical Biology, Graduated May 2017. Started independent research for credit Fall 2016, Spring 2017. 3. Emily Cheney, Biology: Physiology and Biotechnology Track, Graduated May 2019. Started independent research Fall 2016. Enrolled for credit Fall 2016, Spring 2017, Spring 2018. Undergraduate thesis: establishing markers for cellular senescence in irradiated lung fibroblasts. 4. Kylen Soriano, Health and Human Biology (Pre-Med), Graduated May 2019. Started independent research for credit Spring 2017. Enrolled for credit Fall 2017, Spring 2017, Spring 2018. Undergraduate thesis: TGF-b and hypoxia induced epithelial-mesenchymal transition effects on ovarian cancer mechanosensitivity. 5. Elizabeth Clifton, Applied Mathematics and Biology, Graduated May 2019. Started independent research Spring 2017. Enrolled for credit Spring 2017, Fall 2017, Spring 2018. Undergraduate thesis: polyploidal giant cancer cells and their role in aging and chemotherapeutic resistance. 6. Jeffrey Hsu, Biochemistry, Expected Graduation May 2019. Started independent research Fall 2016, Enrolled for credit Fall 2017, Spring 2017, Fall 2018. Undergraduate thesis: characterizing paracrine signaling between ovarian cancer cells and stromal cells in 3D alginate tumor model. 7. Thomas Skipper, Biomedical Engineering, Expected Graduation May 2019. Started independent research Fall 2016. Enrolled for credit Fall 2016, Spring 2018, Fall 2018. Undergraduate thesis: modeling ovarian cancer microenvironments using alginate-gelatin microspheres. 8. Joy Jiang, Biochemistry and Molecular Biology, Expected Graduation May 2019. Started independent research Spring 2018. Enrolled for credit Spring 2018, Fall 2018. Undergraduate thesis: characterizing the morphology and malignancy of polyploidal giant breast cancer cells. 9. Devin Schroeder, Biochemistry and Molecular Biology, Expected Graduation May 2020. Started independent research Fall 2018. Enrolled for credit Fall 2018. Undergraduate thesis: the role of hsa-mir-200b in ovarian cancer cell proliferation and migration.

Postdoctoral Fellow, Brown University 1. Deepraj Ghosh, Postdoctoral research assistant, 2017-present. Project: tumor microenvironment interactions forcing cancer progression - stromal cell aging and breast cancer progression. 2. Nhat Quach, Postdoctoral research assistant, 2018-present. Project: tumor microenvironment interactions in ovarian cancer – niche factor effects on lipid metabolism.

Graduate Students, Georgia Institute of Technology 1. Deepraj Ghosh, PhD Department: Chemical & Biomolecular Engineering Start date: November 2009 Successfully defended his thesis: June 25, 2014

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Thesis title: Therapeutic Effect of Soluble Factor Mediated Mechanical Response of Mesenchymal Stem Cells Awards: 2011 Petit Graduate Mentor Award Current position – Postdoc at Brown University, Dawson Lab 2. Kathleen McAndrews, PhD Department: Chemical & Biomolecular Engineering Start date: November 2010 Successfully defended her thesis: June 25, 2015 Thesis title: Molecular and Mechanical Regulators of the Tumor Microenvironment and Mesenchymal Stem Cell Induced Cancer Progression Awards: Cell and Tissue Engineering Training Grant (2011-2013) Current position – Postdoc at MD Anderson Cancer Center, Kalluri Lab 3. Daniel McGrail, PhD Department: Chemical & Biomolecular Engineering Start date: August 2012 Successfully defended his thesis: June 20, 2015 Thesis title: Development of a High Throughput Mechanomic Screening Approach for Targeting Metastatic Ovarian Cancer Awards: 2013 NSF Graduate Research Fellowship Honorable Mention, IGERT Stem Cell Biomanufacturing Training Grant (2013-2015) Current position – Postdoc at MD Anderson Cancer Center, Lin Lab 4. Kevin Rodriguez, MS Department: Chemical & Biomolecular Engineering Start date: November 2010 Progress toward the degree requirements: Passed qualifying exams, finished courses, completed proposal, and left for personal reasons with course-based master’s degree Awards: 2011 NSF Graduate Research Fellowship Honorable Mention, CD4 GAANN Training Grant (2011) Graduation: Spring 2014 Current position – Sales Engineer at Haver & Boecker 5. Russell Jampol, MS Department: Chemical & Biomolecular Engineering Start date: November 2011 Progress toward the degree requirements: Passed qualifying exams, finished courses, completed proposal Awards: CD4 GAANN Training Grant (2012) Expected graduation: Spring 2015 Current position – Process Development Associate at Amgen

Undergraduate Students, Georgia Institute of Technology 1. Ryan Amos, GT Chemical & Biomolecular Engineering Undergraduate, Spring 2009. Current position - Chemical Process Engineer, Hargrove Engineering. 2. Jake Childs, GT Chemical & Biomolecular Engineering Undergraduate, Spring and Summer 2009. Current position - Senior Consultant, Strategy & Operations at Deloitte.

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3. Daniel McGrail, GT Chemical & Biomolecular Engineering Undergraduate, 2009-2012. Awards - President’s Undergraduate Research Award (2009, 2010, and 2011), Georgia Tech Institute Undergraduate Research Award (2012), Air Products Undergraduate Research Award (2010), Air Products Poster Competition, 3rd Place (2010), Petit Undergraduate Scholar (2011). BS-MS student, joined PhD program. Current position – Postdoc at MD Anderson Cancer Center, Lin Lab. 4. Lauren Sanders, Visiting Undergraduate, Spelman College, Summer 2009. Award - Exxon Undergraduate Research Award. 5. Divine Edem, Visiting Undergraduate, North Carolina State University, Summer 2009. Current position - Process Engineer at Dupont. 6. Sarah McNew, GT Chemical & Biomolecular Engineering Undergraduate, Summer 2009. Current position - Graduate Student, GT. 7. David Boney, GT Chemical & Biomolecular Engineering Undergraduate, Fall 2009-Spring 2010. Current position – Process Engineer at Jacobs. 8. Clint Cheng, GT Chemical & Biomolecular Engineering Undergraduate, Fall 2009-Spring 2010. Current position - Graduate Student at VCU. 9. Eric Lin, GT Chemical & Biomolecular Engineering Undergraduate, Fall 2009 – Spring 2010. Current position - Medical Student at Medical College of GA. 10. Tanisha Bilups, Visiting Undergraduate, Spelman College, Summer 2010 Exxon Undergraduate Research Award. Current position – transferred to NC State. 11. Michelle Park, Visiting Undergraduate, Tulane University, Summer 2010. Award - NSF Summer Undergraduate Research Experience (SURE). Current position – Relief valve engineer at INEOS O&P. 12. Christine Hang, GT Nuclear and Radiological Engineering, Spring 2010 – Fall 2011. Award - President’s Undergraduate Research Award (2010). Current position – Co-founder and CEO at Flow Med Tech. 13. Hasan Khosravi, GT Chemical & Biomolecular Engineering Undergraduate, Spring 2010. Current position – MD candidate at Harvard Medical School. 14. Jae Shin, GT Chemical & Biomolecular Engineering Undergraduate, Spring 2010. 15. Virginia Lin, GT Biomedical Engineering Undergraduate, Spring 2010 – Spring 2011. Other honors - Internship, Medical College of GA (Summer 2010), President’s Undergraduate Research Award (2011). Current position – Biomedical Engineer, Edwards Life Sciences. 16. Harshel Desai, GT Chemical & Biomolecular Engineering Undergraduate, Spring 2010 – Summer 2010. Current position – medical student. 17. Charles Kuo, GT Chemical & Biomolecular Engineering Undergraduate / M.S. Student, 2010-2012. Awards - President’s Undergraduate Research Award (2010), Air Products Undergraduate Research Award (2011), Air Products Poster Competition, 3rd Place (2011). Current position - Graduate Student, University of Maryland 18. Xuan Vuong, GT Biochemistry Undergraduate, Spring 2010. 19. Christine Muzzelo, Visiting Undergraduate, University of Delaware, Summer 2011 NSF Summer Undergraduate Research Experience (SURE). Current position – Graduate student, Villanova University.

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20. Chinelo Ononye, Visiting Undergraduate, Georgia Southern University, Summer 2011, Spring 2014-2015. Awards - Exxon Undergraduate Research Award. Transferred to GT as Chemical & Biomolecular Engineering Undergraduate. 21. Joe Roesner, GT Chemical & Biomolecular Engineering Undergraduate, Summer 2011. Current position – Graduate student, Boston University. Graduate students at Boston University. 22. Hweeyee Han, GT Chemical & Biomolecular Engineering Undergraduate, 2011-2012. Petroleum lab technician. 23. Mark Qi, GT Chemical & Biomolecular Engineering Undergraduate, 2011-2012, 2014. Internship, Duke University (2013). Current position – Process Engineer at Schlumberger. 24. Cecilia Pantoja, GT Biomedical Engineering Undergraduate, 2012. Research associate, Illumina. President’s Undergraduate Research Award (2012). 25. Barbara Zappala, GT Chemical & Biomolecular Engineering Undergraduate, 2012. Strategic data analyst, Academy for Urban School Leadership. 26. Brandon Ling, GT Chemical & Biomolecular Engineering Undergraduate, 2011-2012. Senior software engineer, The Home Depot. 27. Derrick Morton, GT Chemical & Biomolecular Engineering Undergraduate, 2012 28. Nhat Quach, GT Biochemistry Undergraduate, 2011-2012. Awards - President’s Undergraduate Research Award (2010), Undergraduate Research Thesis: Understanding the Role of Soluble Growth Factors and Substrate Rigidity on Human Mesenchymal Stem Cell Osteogenesis (May 4, 2012). PhD, University of Georgia. Currently postdoc in my lab. 29. Eled Gebrihot, Visiting Undergraduate, Georgia Perimeter College, Summer 2012. NSF Summer Undergraduate Research Experience (SURE). Transferred to University of Georgia, Biochemistry. 30. Min Jeong Kim, GT Chemical & Biomolecular Engineering Undergraduate, 2012-2013. Awards - President’s Undergraduate Research Award (2012). 31. Jason Iandoli, GT Biomedical Engineering Undergraduate, 2013. President’s Undergraduate Research Award (2013). 32. Vinh Trang, GT Biochemistry Undergraduate, 2013. President’s Undergraduate Research Award (2013). Current position - Graduate Student, Mercer University Pharmacy Program. 33. Tuyet Lam, GT Biochemistry Undergraduate, 2012-2013. Current position - Graduate Student, Mercer University Pharmacy Program. 34. Niti Khambhati, GT Biochemistry Undergraduate, 2012-2015. President’s Undergraduate Research Award (2014, 2015), Air Products Poster Competition, Honorable Mention (2014), Undergraduate Research Thesis (December 2014): Elucidating and Targeting Biophysical Changes Responsible for Taxol Resistance in Ovarian Cancer Cells. Current position - Medical Student, Medical College of Georgia 35. Jaeyoon Yi, GT Chemical & Biomolecular Engineering Undergraduate, Fall 2014 – Spring 2015. Air Products Undergraduate Research Award (2014). 36. Quang Minh Kieu, GT Chemical & Biomolecular Engineering Undergraduate, 2013-2015. President’s Undergraduate Research Award (2014), Air Products Undergraduate Research Award (2013), Sigma Xi Undergraduate Research Award (2014). Current position – Staff Scientist, Merck

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37. Krishan Patel, GT Chemical & Biomolecular Engineering Undergraduate, Spring 2014- 2015. Current position – Process Engineer, Dennis Group 38. Chandler Brandenburg, GT Chemical & Biomolecular Engineering Undergraduate, Summer 2014 – 2015. 39. Nithin Ravikumar, GT Chemical & Biomolecular Engineering Undergraduate, Summer 2014 – 2015. Air Products Undergraduate Research Award (2014). Current position – medical school 40. Blake Lash, GT Biomedical Engineering Undergraduate, Summer 2015-present. Petit Scholar (2015). Current position – graduate student, MIT. 41. Christian Burns, Central Michigan University (2015). NSF Summer Undergraduate Research Experience (SURE). 42. Robert Cowles, GT Chemical & Biomolecular Engineering Undergraduate, Summer 2015- present. 43. Dalton Snyder, GT Chemical & Biomolecular Engineering Undergraduate, Summer 2015- present.

Postdoctoral Fellows and Visiting Scholars, Georgia Institute of Technology 1. Adrian Katona, Postdoctoral research assistant, 2009. 2. Dustin Zuelke, Lab technician, 2010. Current position - Graduate Student, University of New York 3. Deepraj Ghosh, Postdoctoral research assistant, 2015-present. Current position – Postdoc, Brown University, Dawson lab. 4. Shabnam Gupta, Emory University Medical Student, Spring 2015 – present. Current position – Resident, MGH.

High School Interns, Georgia Institute of Technology 1. Brett Jones, Wheeler High School Senior Intern, 2009. Project manager, UGA. 2. Kathleen Allen, Dunwoody High School Intern, 2011. Graduated from UGA. 3. Ronald Shanderson, Wheeler High School Intern, 2011. Graduate student, Stanford University. 4. Saachi Datta, Galloway High School Intern, 2015. Undergraduate at UPENN.

OTHER TEACHING ACTIVITIES

Session moderator or speaker, Nuts and Bolts of Finding First Faculty Position 1. Conference of the Ford Fellows (2010, 2011, 2012, 2013, 2014, 2015, 2016, 2017, 2018) 2. Georgia Tech Chemical & Biomolecular Engineering Future Faculty Program (2012) 3. Harvard Medical School Department of Continuing Education (2008)

Science and engineering / education workshops 1. Harvard Medical School: Career Advancement and Leadership Skills for Women in Healthcare Conference, Boston, MA 2018. 2. NSF EFRI Workshop, Convergence and Interdisciplinarity in Advancing Larger Scale Research, Washington DC, 2018.

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3. Graduate Student Orientation, Focusing Professional Activities to Build a Strong CV, Brown University, Providence, RI, 2017. 4. NSF Includes Broadening Participation in STEM Conference, San Diego, CA, 2016. 5. NSF BRIGE Principal Investigator Conference, Washington, DC, 2011. 6. NSF Career Development Workshop, University of Florida, 2009. 7. College of Engineering, Pennsylvania State University, 2004

PROFESSIONAL CONTRIBUTIONS / SERVICE

Advisory Roles Faculty Advisory Board, Louisiana Tech University, Biomedical Engineering Program, 2011- 2017.

Scientific Sessions and Conferences Organized and Chaired 1. Co-chair, Conference of the Ford Fellows, 2014. 2. Planning committee, GT Minority Faculty Development Workshop, 2013. 3. Planning committee, Conference of the Ford Fellows, 2011. 4. Planning committee, Conference of the Ford Fellows, 2013. 5. Planning committee, Conference of the Ford Fellows, 2014. 6. Co-chair and organizer, Department of Chemical and Biomolecular Engineering Graduate Student Seminar Series, The Johns Hopkins University, 2004.

Editorial Board Member 1. AIMS Cell and Tissue Engineering (2016-present). 2. Scientific Reports (2017-present). 3. PLoS One (2018-present).

Journal Review Activities 1. ACS Biomaterials 2. Annals of Biomedical Engineering 3. Biophysical Journal 4. Biotechnology and Bioengineering 5. BMC Cancer 6. British Journal of Hematology 7. Cell Communication and Signaling 8. Cytoskeleton 9. Journal of Clinical and Experimental Metastasis 10. Journal of Controlled Release 11. Journal of Pharmaceutical Science 12. Journal of Royal Society Interface 13. JOVE 14. Molecular Cancer Research 15. Molecular Imaging 16. Molecular Pharmaceutics

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17. Nature Communications 18. Nature Methods 19. Optics Express 20. PLoS One 21. PNAS 22. Scientific Reports 23. Stem Cell

Panel Review 1. National Science Foundation 2. Department of Defense Cancer Research Programs 3. National Institute of Health 4. Ford Foundation

Administrative Duties in Professional Societies 1. Session Chair, American Institute of Chemical Engineers, Drug Delivery (2009-2011), Biomechanics (2012-2013), In vivo imaging (2013), Stem Cells in Aging (2014) 2. Session Chair, American Chemical Society, Stem Cell Based Therapies (2013) 3. Session Chair, Biomedical Engineering Society, Stem Cells (2013)

Public and Community Service 1. Wheeler High School Internship Program Mentor (2009-present). 2. Direct-to-Discover K12 Outreach Program Scientist (2009-present).

Institute Contributions 1. Brown University MCB Faculty Retreat Chair, 2018. 2. Brown University MCB Faculty Retreat Co-Chair, 2017. 3. Brown University MCB Graduate Recruitment Committee, 2017. 4. Brown University MPP Seminar Committee, 2017-2018. 5. Brown University MCB Diversity Committee, 2017-2018. 6. GT Goizueta STEM Initiative Faculty Advisory Board Member, 2011. 7. GT Bioengineering Faculty Advisory Committee, 2012-2015. 8. GT Chemical & Biomolecular Engineering Safety Committee, 2010-2014. 9. GT Chemical & Biomolecular Engineering Graduate Studies Committee, 2009-present. 10. GT Chemical & Biomolecular Engineering Faculty Search Committee, 2014. 11. GT Chemical & Biomolecular Engineering Graduate Admissions Committee, 2014. 12. Developed and Implemented GT Chemical & Biomolecular Engineering Responsible Conduct of Research (RCR) Training Plan, 2012. 13. GT Sloan/UCEM Advisory Committee, 2013-2015. 14. GT SHPE Xerox Scholarship Selection Committee, 2013-2014. 15. GT Sigma Xi Student Research Awards Committee, 2013. 16. GT Sigma Xi Student Research Awards Committee, 2010.

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