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Protein Crystallography from the Perspective of Technology Developments
Crystallography Reviews ISSN: 0889-311X (Print) 1476-3508 (Online) Journal homepage: http://www.tandfonline.com/loi/gcry20 Protein crystallography from the perspective of technology developments Xiao-Dong Su, Heng Zhang, Thomas C. Terwilliger, Anders Liljas, Junyu Xiao & Yuhui Dong To cite this article: Xiao-Dong Su, Heng Zhang, Thomas C. Terwilliger, Anders Liljas, Junyu Xiao & Yuhui Dong (2015) Protein crystallography from the perspective of technology developments, Crystallography Reviews, 21:1-2, 122-153, DOI: 10.1080/0889311X.2014.973868 To link to this article: http://dx.doi.org/10.1080/0889311X.2014.973868 Published online: 13 Dec 2014. Submit your article to this journal Article views: 304 View related articles View Crossmark data Full Terms & Conditions of access and use can be found at http://www.tandfonline.com/action/journalInformation?journalCode=gcry20 Download by: [Peking University] Date: 18 November 2015, At: 02:19 Crystallography Reviews, 2015 Vol. 21, Nos. 1–2, 122–153, http://dx.doi.org/10.1080/0889311X.2014.973868 REVIEW ARTICLE Protein crystallography from the perspective of technology developments Xiao-Dong Sua∗, Heng Zhanga, Thomas C. Terwilligerb, Anders Liljasc, Junyu Xiaoa and Yuhui Dongd aState Key Laboratory of Protein and Plant Gene Research, and Biodynamic Optical Imaging Center (BIOPIC), School of Life Sciences, Peking University, Beijing 100871, People’s Republic of China; bBioscience Division, Los Alamos National Laboratory, Mail Stop M888, Los Alamos, NM 87545, USA; cDepartment of Biochemistry and Structural Biology, Lund University, Lund, Sweden; d Beijing Synchrotron Radiation Facility, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, People’s Republic of China (Received 2 October 2014; accepted 3 October 2014) Early on, crystallography was a domain of mineralogy and mathematics and dealt mostly with symmetry properties and imaginary crystal lattices. -
Annual Report 2013.Pdf
ATOMIC HERITAGE FOUNDATION Preserving & Interpreting Manhattan Project History & Legacy preserving history ANNUAL REPORT 2013 WHY WE SHOULD PRESERVE THE MANHATTAN PROJECT “The factories and bombs that Manhattan Project scientists, engineers, and workers built were physical objects that depended for their operation on physics, chemistry, metallurgy, and other nat- ural sciences, but their social reality - their meaning, if you will - was human, social, political....We preserve what we value of the physical past because it specifically embodies our social past....When we lose parts of our physical past, we lose parts of our common social past as well.” “The new knowledge of nuclear energy has undoubtedly limited national sovereignty and scaled down the destructiveness of war. If that’s not a good enough reason to work for and contribute to the Manhattan Project’s historic preservation, what would be? It’s certainly good enough for me.” ~Richard Rhodes, “Why We Should Preserve the Manhattan Project,” Bulletin of the Atomic Scientists, May/June 2006 Photographs clockwise from top: J. Robert Oppenheimer, General Leslie R. Groves pinning an award on Enrico Fermi, Leona Woods Marshall, the Alpha Racetrack at the Y-12 Plant, and the Bethe House on Bathtub Row. Front cover: A Bruggeman Ranch property. Back cover: Bronze statues by Susanne Vertel of J. Robert Oppenheimer and General Leslie Groves at Los Alamos. Table of Contents BOARD MEMBERS & ADVISORY COMMITTEE........3 Cindy Kelly, Dorothy and Clay Per- Letter from the President..........................................4 -
Technological Entrepreneurship – a Key to World Peace and Prosperity”
cc MM CoCorrmickmick NorthwesternNorthwestern Engineering Engineering MaterialMaterialss ScienceScience and and EngineeringEngineering The 2014 McCormick Dean’s Seminar Series Dr. Dan Shechtman – Nobel Laureate Israel Institute of Technology Monday, October 20, 2014 4:00pm, McCormick Auditorium (Allen Center) Reception to follow north of McCormick Auditorium in the Allen Center “Technological Entrepreneurship – a Key to World Peace and Prosperity” Most of the countries in the world lack significant natural resources and are characterized by low standard of living with little hope for improvement due to population growth and mismanagement. This is true also for countries that are rich in natural resources, but do not use them wisely. People that live in countries that enjoy high standard of living are industrious and their countries industrial. The basic reason of this division is technological entrepreneurship nourished by free market economy. Technologically entrepreneurial people make the difference. So, is there hope for everybody on the globe to improve their lives? Can technological entrepreneurship be motivated and taught so that generations of determined entrepreneurs will build up thriving economies? The clear answer to both questions is yes, but the process will take time and dedication. It all starts with education in general and scientific- technical education in particular. There is also a way to expedite the process – start with the already educated engineers and scientists. These are the first candidates for entrepreneurial endeavors. They can do it, but need motivation, continuous instruction and encouraging economic environment until they create successful start-ups and serve as role models for others. The name of the game is motivation. -
Goessmann, Lindsey, Chamberlain, Peters, and Mcewen, Research Symposium
GOE SSMANNgazette A Publication of the Chemistry Department University of Massachusetts Amherst www.chem.umass.edu VOLUME 44 – SPRING 2015 INSIDE Alumni News ............................2 by David Adams Points of Pride ...........................4 Chemistry Loses a Dear Friend Lab Notes .................................5 Dissertation Seminars .............21 On April 14th one of the towering figures of the Chemistry Seminar Program ....................20 Department, Professor George R. Richason, Jr. passed away Senior Awards Dinner .............22 at Cooley Dickinson Hospital in Northampton. Alongside Degrees Awarded ...................22 Goessmann, Lindsey, Chamberlain, Peters, and McEwen, Research Symposium ..............23 George takes his place among the chemists who shaped Friends of Chemistry ...............26 and propelled the department to national and international Letter from Head ....................28 quality and recognition. In George’s case, he was part of EVENTS for 2015 the Chemistry Department for 82 of its 146 year history! His contributions to the department and the university Five College Seminar were profound, widespread, and legendary. In many Prof. Phil Baran Scripps Institute respects he truly was “Mr. UMass.” March 10, 2015 In the early 1930s, George, born in the Riverside Marvin Rausch Lectureship Prof. Karl Wieghardt section of Turner’s Falls on April 3, 1916, participated in Max-Planck-Institut-Mülheim basketball tournaments on the Amherst campus of the then April 9, 2015 Massachusetts Agricultural College (MAC). MAC became Senior Awards Dinner Massachusetts State College in 1931, and George April 29, 2015 matriculated at MSC in the fall of 1933. Early in his undergraduate career the basketball coach Getting to Know Our Newest Alumni Reunion 2015 June 6, 2015 encouraged him to join the State basketball team Faculty Members after watching him play in Curry Hicks Cage. -
2006Spring.Pdf
− X8 PROTEUM THE ULTIMATE STRUCTURAL BIOLOGY SYSTEM When you need the best system for Structural Biology, the Bruker X8 PROTEUM offers high-throughput screening AND superb high resolution data in one uncompromising package. With our MICROSTAR family of generators, you can rely on the extremely intense micro-focus X-ray beam coupled with the ultra-bright HELIOS optics to handle everything from small crystals to large unit cells With over 700135 detector CCD detectors for speed, installed, sensitivity, we know size and how dynamic to optimize range the to give PLATINUM you the best data possible in the home lab Our KAPPA goniometer’s high precision mechanics allow you to orient the sample along any axis in reciprocal space, while having easy access to mount, cool or anneal your crystals Get the best data, get the fastest system, get the power to solve your structures – X8 PROTEUM. BRUKER ADVANCED X-RAY SOLUTIONS North America: BRUKER AXS INC Tel. (+1) (608) 276-3000 Fax (+1) (608) 276-3006 www.bruker-axs.com [email protected] Germany: BRUKER AXS GMBH Tel. (+49) (721) 595- 2888 Fax (+49) (721) 595-4587 www.bruker-axs.de [email protected] Netherlands: BRUKER AXS BV Tel. (+31) (15) 215-2400 Fax (+31) (15) 215-2500 www.bruker-axs.nl [email protected] American Crystallographic Association * REFLECTIONS *see page 9 for notes on our new name and for new logo possibilities Cover: Images from Warren Award Recipient Charles Majkrazk and his colleagues; see page 25. ACA HOME PAGE: hwi.buffalo.edu/ACA/ Table of Contents 3 President’s -
Download Biozoom
NO. 2 2018 VOLUME 20 DANISH SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY – WWW.BIOKEMI.ORG Din partner inden for salg, service og kalibrering af laboratorie- og pipetteringsudstyr Nyt automatiseringsinstrument fra Integra Viaflo Med Assist Plus bliver rutine pipetterings- opgaver lettere og ensartet • Features som: • Fyldning af plader • Fortyningsrækker • Plader fra 12 til 384 brønde • Automatisk spidspåsætning • Automatisk spidsafskydning • Racks til forskellige rør • Programmering via PC Assist Plus er tilgængelig på det danske marked fra november 2018. Ønsker du flere informationer eller bestille tid til en demo, så kontakt os allerede nu. Skriv til Kirsten Thuesen [email protected] Saml dine akkrediterede kalibreringer af vægte og pipetter hos os DANAK har godkendt Dandiag (Reg. nr. 490) til at udføre akkrediterede kalibreringer af laboratorie vægte fra 1 mg og optil 72 kg. Det betyder, at vi nu kan tilbyde dig, at stå for dine akkrediterede kalibreringer på dine vægte og pipetter. For dig betyder det, at du kun behøver at ringe ét sted, når du skal bruge hjælp til at få foretaget disse kalibreringer. Så ønsker du en høj præcision eller skal I auditeres, har du fordele ved at anvende os. Det er nu nemt, trygt og oplagt at samle dine bestillinger her, hvor du kender kvaliteten som Dandiag står for. Har du brug for at spare tid, så bestil dine vægte og pipetter med en akkrediteret kalibrering. Med et kalibreringscertifikat fra Dandiag får du en garanti for, at dit udstyr er kalibreret i henhold til ISO 8655 (pipetter) og ISO 17025, hvilket kan bruges i forhold til dine egne krav. Dandiag A/S Baldershøj 19 DK-2635 Ishøj Tlf. -
Interview with Linus Pauling
LINUS PAULING (1901-1994) INTERVIEWED BY JOHN L. GREENBERG May 10, 1984 Photo by M. Opalenik c. 1964 ARCHIVES CALIFORNIA INSTITUTE OF TECHNOLOGY Pasadena, California Subject area Chemistry Abstract Interview in 1984 with Linus Pauling, professor of chemistry emeritus. He recalls his instructorship in quantitative analysis at Oregon Agricultural College at age 18. To Caltech for graduate study, 1922. As preparation, Arthur Amos Noyes sent him proof sheets of Noyes’s new book, Chemical Principles. Studied X-ray crystallography with Roscoe G. Dickinson. Gave seminar on Debye-Hückel theory of electrolytic solutions for visiting P. J. W. Debye. Recollections of Noyes (then chairman of the Division of Chemistry and Chemical Engineering), Dickinson, and Ralph W. G. Wyckoff. Discusses X-ray crystallography and its history. Recollections of Gilbert N. Lewis, Caltech’s rivalry with Berkeley. Paper with Richard C. Tolman on residual entropy of crystals; recalls courses with Tolman. Offer of professorship at Harvard in 1929 and MIT c. 1930. Death of Noyes (1936) and Pauling’s appointment as chairman of chemistry division (1937). Remarks on Biology Division and advent of Thomas Hunt Morgan (1928). Work on hemoglobin in mid-1930s. Remarks on Karl Landsteiner and immunology. Lectures on “complementariness” as basis of biological specificity; paper with Max Delbrück. Projected book on the molecular basis of biological specificity, to be called The Nature of Life. Recollections of Albert Tyler and http://resolver.caltech.edu/CaltechOH:OH_Pauling_L George W. Beadle. Comments on relations with Warren Weaver and Rockefeller Foundation. Discusses work on protein structure and discovery of alpha helix. Discusses his reasons for leaving Caltech in 1963 and the attitude of Caltech president Lee DuBridge and John Roberts, then chair of the chemistry division. -
Date: To: September 22, 1 997 Mr Ian Johnston©
22-SEP-1997 16:36 NOBELSTIFTELSEN 4& 8 6603847 SID 01 NOBELSTIFTELSEN The Nobel Foundation TELEFAX Date: September 22, 1 997 To: Mr Ian Johnston© Company: Executive Office of the Secretary-General Fax no: 0091-2129633511 From: The Nobel Foundation Total number of pages: olO MESSAGE DearMrJohnstone, With reference to your fax and to our telephone conversation, I am enclosing the address list of all Nobel Prize laureates. Yours sincerely, Ingr BergstrSm Mailing address: Bos StU S-102 45 Stockholm. Sweden Strat itddrtSMi Suircfatan 14 Teleptelrtts: (-MB S) 663 » 20 Fsuc (*-«>!) «W Jg 47 22-SEP-1997 16:36 NOBELSTIFTELSEN 46 B S603847 SID 02 22-SEP-1997 16:35 NOBELSTIFTELSEN 46 8 6603847 SID 03 Professor Willis E, Lamb Jr Prof. Aleksandre M. Prokhorov Dr. Leo EsaJki 848 North Norris Avenue Russian Academy of Sciences University of Tsukuba TUCSON, AZ 857 19 Leninskii Prospect 14 Tsukuba USA MSOCOWV71 Ibaraki Ru s s I a 305 Japan 59* c>io Dr. Tsung Dao Lee Professor Hans A. Bethe Professor Antony Hewlsh Department of Physics Cornell University Cavendish Laboratory Columbia University ITHACA, NY 14853 University of Cambridge 538 West I20th Street USA CAMBRIDGE CB3 OHE NEW YORK, NY 10027 England USA S96 014 S ' Dr. Chen Ning Yang Professor Murray Gell-Mann ^ Professor Aage Bohr The Institute for Department of Physics Niels Bohr Institutet Theoretical Physics California Institute of Technology Blegdamsvej 17 State University of New York PASADENA, CA91125 DK-2100 KOPENHAMN 0 STONY BROOK, NY 11794 USA D anni ark USA 595 600 613 Professor Owen Chamberlain Professor Louis Neel ' Professor Ben Mottelson 6068 Margarldo Drive Membre de rinstitute Nordita OAKLAND, CA 946 IS 15 Rue Marcel-Allegot Blegdamsvej 17 USA F-92190 MEUDON-BELLEVUE DK-2100 KOPENHAMN 0 Frankrike D an m ar k 599 615 Professor Donald A. -
ABSTRACT NIX, ANISHA MAHESH. Investigating
ABSTRACT NIX, ANISHA MAHESH. Investigating the Links Among Stereotypes, Self-Image, and Career Commitment to the Sciences. (Under the direction of Mary B. Wyer). Women have historically been underrepresented in the science, technology, engineering, and mathematics (STEM) fields. One reason for this continued underrepresentation might be existing stereotypes of STEM fields, as well as the lack of historical role models within these fields. A longitudinal analysis conducted over a one- semester period in an introductory Chemistry course was conducted to explore the effects of a curriculum intervention that introduced the contributions of women to chemistry on students’ stereotypes about STEM fields, self perceptions, and their commitment to STEM fields. Results indicate that stereotypes about scientists in this sample include masculine, feminine, and neutral characteristics and that there was some change in stereotypes after the intervention. Furthermore, women in the sample had higher career commitment to the sciences than men and women who were STEM majors had a better fit between stereotypes and self perceptions than did women who were not STEM majors. Investigating the Links Among Stereotypes, Self-Image, and Career Commitment to the Sciences by Anisha Mahesh Nix A thesis submitted to the Graduate Faculty of North Carolina State University in partial fulfillment of the requirements for the degree of Master of Science Psychology Raleigh, North Carolina 2009 APPROVED BY: _______________________________ ______________________________ Dennis O. Gray Shevaun Neupert ________________________________ Mary B. Wyer Chair of Advisory Committee DEDICATION This work is dedicated to my family. To my mother, whose support and guidance have been invaluable in my education and my life. -
ACA Structure Matters, Winter 2017
ACA Isabella Karle (1921-2017) Winter 2017 Structure Matters Remembering Isabella Karle “I need to tackle this scientific problem, what techniques are Isabella Karle (1921 - 2017), retired from the Naval Research available to help me do it?” and when she found out what they Laboratory (Washington, DC) after more than six decades there, were she would solve the problem. In this case she worked with passed away on October 3, 2017, at the age of 95, from a brain silica tubes that she had made, filled with crude plutonium oxide tumor. Early on Isabella was told by a teacher that chemistry and chemical reactants, and inserted them in a hole in a large was not a “proper field for girls” but she went on to become a block of copper that was heated to high temperatures of 800 to member of the National Academy of Sciences. She received the 900 degrees Centigrade. After many experiments under difficult 1988 Gregori Aminoff Prize from the Royal Swedish Academy conditions, she ended up, triumphantly, with bright green crystals of plutonium chloride (PuCl ) that she passed on to the physics of Sciences, the 1993 Bower Award and Prize for Achievement 3 in Science and, in 1995, received the National Medal of Science. branch of the Manhattan project. What follows are remembrances from several of her colleagues. Isabella approached direct methods in the same way, to the delight of her husband Jerry, who won the Nobel Prize for his work on them. She worked hard to find how to run direct methods correctly and then was able to help others. -
A Retirement Celebration Honoring Prof. Robert K. Boeckman, Jr
A Retirement Celebration Honoring Prof. Robert K. Boeckman, Jr. Symposium Lander Auditorium, 9:00 am — 5:00 pm Lunch Munnerlyn Atrium, 12:30 pm Cocktail Reception/Dinner Oakhill Country Club, 6:30 pm Robert K. Boeckman, Jr. was born August 26, 1944 in Pasadena, California. After early schooling in Dayton, Ohio, he received his Bachelors of Science degree in Chemistry in 1966 from Carnegie Institute of Technology (now Carnegie Mellon University). He moved on to Brandeis University where he received the Ph.D. degree under the supervision of James B. Hendrickson and Ernest Grunwald in 1970. He then joined the research group of Gilbert Stork in 1970 as an NIH postdoctoral fellow. He began his academic career at Wayne State University in 1972, where he rose to the rank of Professor in 1979. In 1980, he joined the faculty of the University of Rochester where he is currently Marshall D. Gates Jr. Professor of Chemistry. In 1976, he was married to Mary H. Delton. Among his academic honors are included an A.P. Sloan Fellowship, a Research Career Development Award from the National Institutes of Health, and an ACS Cope Scholar Award. He has been a Fellow of the Japanese Society for the Promotion of Science, was twice awarded an Alexander Von Humboldt Stiftung Research Prize for Senior Scientists, and named a Marshall Gates Scholar by the University of Rochester. He is an inaugural ACS Fellow and a Fellow of the AAAS. From 1997 until 2016, he served as an Associate Editor of the Journal of Organic Chemistry. He served as Chair of the Department of Chemistry at the University of Rochester from 2003-2013 and in 2009 received the William H. -
Contents Contents
Contents CHEMISTRY International January-March 2019 Volume 41 No. 1 Introduction The International Year of the Periodic Table 2019 2 by Jan Reedijk and Natalia Tarasova Features IUPAC and the Periodic Table by G.J. Leigh 6 Criteria for New Element Discovery: Providing Assurance 10 in a Field of Allure and Romance by Sigurd Hofmann Looking Backwards and Forwards at the Development 16 of the Periodic Table by Eric Scerri Isotopic Abundances and Atomic Weights: History of IUPAC 21 Commission II.1 in the Service of Chemistry by John R. De Laeter IUPAC Commission II.1 Today by Juris Meija 24 Isotopes Matter by Norman E. Holden, Tyler B. Coplen, and Peter Mahaffy 27 The New SI: The International System of Units is Getting 32 a Makeover by Ian Mills and Roberto Marquardt IUPAC Wire Election of IUPAC Officers and Bureau Members 36 Juris Meija Made the Top 40 Under 40 37 C. Oliver Kappe is Awarded the 2018 IUPAC-ThalesNano Prize 37 for Flow Chemistry OPCW to Further Enhance Contributions to United Nations’ 38 Sustainable Development Goals 1001 Inventions: Journeys from Alchemy to Chemistry 38 Stamps International 39 Project Place Critical evaluation of homogeneous equilibrium and solubility 40 constants of gadolinium in environmental and biological- relevant conditions 23rd UNESCO/IUPAC Postgraduate Course in Polymer Science 40 Guidance for the Compilation, Critical Evaluation and 40 Dissemination of Chemical Data Making an imPACt On the Discovery of New Elements (IUPAC/IUPAP 42 Provisional Report) IUPAC Periodic Table of the Elements and Isotopes