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Status and Vision for Structural Biology at the Canadian Light Source P
Vol. 121 (2012) ACTA PHYSICA POLONICA A No. 4 Proceedings of the 9th National Symposium of Synchrotron Radiation Users, Warsaw, September 2627, 2011 Status and Vision for Structural Biology at the Canadian Light Source P. Grochulskia;b∗, M.N. Fodjea;c and G. Georged a Canadian Light Source, 101 Perimeter Road, Saskatoon, SK S7N 0X4 Canada b College of Pharmacy and Nutrition, University of Saskatchewan, 110 Science Place, Saskatoon, SK S7N 5C8, Canada c Department of Biochemistry, University of Saskatchewan, 107 Wiggins Road, Saskatoon SK S7N 5E5, Canada dDepartment of Geology, University of Saskatchewan, 114 Science Place, Saskatoon, SK S7N 5E2, Canada The status and vision for Structural Biology at the Canadian Light Source (CLS) is presented. The beamlines that have been described in the paper represent a Canadian national resource that is available to science and industry world-wide. They include state-of-the-art infrastructure and include specialized capabilities, many of which are not available elsewhere, including macromolecular crystallography, biological X-ray spec- troscopy, soft X-ray spectromicroscopy, as well as small angle and wide angle X-ray scattering beamlines. The vision for Structural Biology at the Canadian Light Source is signicantly enhanced by the synergies and col- laborations between the users of the dierent beamlines and by the strengths of the scientic personnel and trainees. PACS: 87.64.kd, 87.80.Dj 1. Introduction TABLE I 2.53.0 GeV synchrotron facilities worldwide and the The Canadian Light Source (CLS) is a 2.9 GeV na- number of MX, BioXAS and BioSAXS/WAXS beamlines tional synchrotron radiation facility located at the Uni- versity of Saskatchewan in Saskatoon. -
Annual Report 2013.Pdf
ATOMIC HERITAGE FOUNDATION Preserving & Interpreting Manhattan Project History & Legacy preserving history ANNUAL REPORT 2013 WHY WE SHOULD PRESERVE THE MANHATTAN PROJECT “The factories and bombs that Manhattan Project scientists, engineers, and workers built were physical objects that depended for their operation on physics, chemistry, metallurgy, and other nat- ural sciences, but their social reality - their meaning, if you will - was human, social, political....We preserve what we value of the physical past because it specifically embodies our social past....When we lose parts of our physical past, we lose parts of our common social past as well.” “The new knowledge of nuclear energy has undoubtedly limited national sovereignty and scaled down the destructiveness of war. If that’s not a good enough reason to work for and contribute to the Manhattan Project’s historic preservation, what would be? It’s certainly good enough for me.” ~Richard Rhodes, “Why We Should Preserve the Manhattan Project,” Bulletin of the Atomic Scientists, May/June 2006 Photographs clockwise from top: J. Robert Oppenheimer, General Leslie R. Groves pinning an award on Enrico Fermi, Leona Woods Marshall, the Alpha Racetrack at the Y-12 Plant, and the Bethe House on Bathtub Row. Front cover: A Bruggeman Ranch property. Back cover: Bronze statues by Susanne Vertel of J. Robert Oppenheimer and General Leslie Groves at Los Alamos. Table of Contents BOARD MEMBERS & ADVISORY COMMITTEE........3 Cindy Kelly, Dorothy and Clay Per- Letter from the President..........................................4 -
ACA Structure Matters, Winter 2017
ACA Isabella Karle (1921-2017) Winter 2017 Structure Matters Remembering Isabella Karle “I need to tackle this scientific problem, what techniques are Isabella Karle (1921 - 2017), retired from the Naval Research available to help me do it?” and when she found out what they Laboratory (Washington, DC) after more than six decades there, were she would solve the problem. In this case she worked with passed away on October 3, 2017, at the age of 95, from a brain silica tubes that she had made, filled with crude plutonium oxide tumor. Early on Isabella was told by a teacher that chemistry and chemical reactants, and inserted them in a hole in a large was not a “proper field for girls” but she went on to become a block of copper that was heated to high temperatures of 800 to member of the National Academy of Sciences. She received the 900 degrees Centigrade. After many experiments under difficult 1988 Gregori Aminoff Prize from the Royal Swedish Academy conditions, she ended up, triumphantly, with bright green crystals of plutonium chloride (PuCl ) that she passed on to the physics of Sciences, the 1993 Bower Award and Prize for Achievement 3 in Science and, in 1995, received the National Medal of Science. branch of the Manhattan project. What follows are remembrances from several of her colleagues. Isabella approached direct methods in the same way, to the delight of her husband Jerry, who won the Nobel Prize for his work on them. She worked hard to find how to run direct methods correctly and then was able to help others. -
70Th Anniversary of the Manhattan Project Atomic Heritage Foundation
Atomic Heritage Foundation presents 70th Anniversary of the Manhattan Project June 2 and 3, 2015 Carnegie Institution for Science 1530 P Street, NW Washington, DC 20005 Visit our merchandise tables to purchase books, posters, and hats! Manhattan Project 70th Anniversary Manhattan Project veterans Lawrence S. O’Rourke (left) and William E. Tewes (right) with his future wife, Olive. The Atomic Heritage Foundation is proud to host events commemorating the 70th Anniversary of the Manhattan Project. It took more than half a million people to build the world’s first atomic bombs; we are honored to welcome more than a dozen men and women who participated in that astonishing effort. The 70th Anniversary Reunion on June 2 will be an opportunity for vet- erans and family members to share their memories and catch up with old friends. Veterans from Los Alamos, Oak Ridge, Hanford, Chicago and other locations will discuss how each site contributed to the Manhattan Project in its own unique way. The 70th Anniversary commemoration will continue on June 3 with a day- long symposium, which will feature a discussion of the new Manhattan Project National Historical Park. We have assembled a first-class roster of Manhattan Project veterans and experts who will discuss topics ranging from innovation to women in science to atomic spies and more. We hope you enjoy the events! Cynthia C. Kelly President, Atomic Heritage Foundation Atomic Heritage Foundation The Atomic Heritage Foundation (AHF), founded by Cynthia C. Kelly in 2002, is a nonprofit organization in Washington, DC, dedicated to the preservation and interpretation of the Manhattan Project and its legacy. -
Winter for the Membership of the American Crystallographic Association, P.O
AMERICAN CRYSTALLOGRAPHIC ASSOCIATION NEWSLETTER Number 4 Winter 2004 ACA 2005 Transactions Symposium New Horizons in Structure Based Drug Discovery Table of Contents / President's Column Winter 2004 Table of Contents President's Column Presidentʼs Column ........................................................... 1-2 The fall ACA Council Guest Editoral: .................................................................2-3 meeting took place in early 2004 ACA Election Results ................................................ 4 November. At this time, News from Canada / Position Available .............................. 6 Council made a few deci- sions, based upon input ACA Committee Report / Web Watch ................................ 8 from the membership. First ACA 2004 Chicago .............................................9-29, 38-40 and foremost, many will Workshop Reports ...................................................... 9-12 be pleased to know that a Travel Award Winners / Commercial Exhibitors ...... 14-23 satisfactory venue for the McPherson Fankuchen Address ................................38-40 2006 summer meeting was News of Crystallographers ...........................................30-37 found. The meeting will be Awards: Janssen/Aminoff/Perutz ..............................30-33 held at the Sheraton Waikiki Obituaries: Blow/Alexander/McMurdie .................... 33-37 Hotel in Honolulu, July 22-27, 2005. Council is ACA Summer Schools / 2005 Etter Award ..................42-44 particularly appreciative of Database Update: -
Summit White Papers
Background Materials and White Papers for the NSF ADVANCE Summit on the Advancement of Senior Women Scientists at Liberal Arts Colleges June 2–4, 2010 • Summit Schedule • Faculty Engagement and Career Satisfaction at Liberal Arts Colleges, Kerry K. Karukstis • Why Does Mentoring End? Cindy Blaha, Amy Bug, Anne Cox, Linda Fritz, Barbara Whitten • Improving Communication Skills: Being Heard on a Regular Basis, Laura L. Wright • Integrating Work and a Personal Life: Aspects of Time and Stress Management for Senior Women Science Faculty, Julie T. Millard and Nancy S. Mills • Improving Professional Development and Morale for Senior Women Faculty, Miriam Rossi • Support from Academe - Identifying departmental and institutional resources, policies, and infrastructure to support senior women STEM faculty, Ruth Beeston, Jill Granger, Leslie Lyons, Darlene Loprete, and Carol Ann Miderski • Leadership Support for Women Faculty Members in Science, Technology, Engineering and Mathematics (STEM) Disciplines at Liberal Arts Colleges (LAC): Perspectives on Practices, Policies and Infrastructure Related to the Position of Department Chair, Bridget L. Gourley • Publications • K. K. Karukstis, “Women in Science, Beyond the Research University: Overlooked and Undervalued,” The Chronicle of Higher Education 55 41 p. 23 (2009). • L. Wright, “Strength in Numbers”, Furman Magazine, Summer 2009, pp. 8-9 http://www.furman.edu/fumag/summer09/summer2009.pdf • K. K. Karukstis, B. L. Gourley, L. L. Wright, M. Rossi, “Mentoring Strategies To Recruit and Advance Women in Science and Engineering,” Journal of Chemical Education, 87, 355-356 (2010). • List of Participants This material is based upon work supported by the National Science Foundation under Grants No. NSF-HRD-061840, 0619027, 0619052, and 0619150. -
SCIENCE HISTORY INSTITUTE ISABELLA KARLE and JEROME
SCIENCE HISTORY INSTITUTE ISABELLA KARLE and JEROME KARLE Transcript of an Interview Conducted by James J. Bohning and David K. Van Keuren at Naval Research Laboratory Washington, District of Columbia on 26 February, 15 June and 9 September 1987 (With Subsequent Corrections and Additions) Upon Isabella Karle’s death in 2017, this oral history was designated Free Access. Please note: This oral history is protected by U.S. copyright law and shall not be reproduced or disseminated in any way without the express permission of the Science History Institute. Users citing this interview for purposes of publication are obliged under the terms of the Center for Oral History, Science History Institute, to credit the Science History Institute using the format below: Isabella Karle and Jerome Karle, interview by James J. Bohning and David K. Van Keuren at Naval Research Laboratory, Washington, District of Columbia, 26 February, 15 June and 9 September 1987 (Philadelphia: Science History Institute, Oral History Transcript # 0066). Formed by the merger of the Chemical Heritage Foundation and the Life Sciences Foundation, the Science History Institute collects and shares the stories of innovators and of discoveries that shape our lives. We preserve and interpret the history of chemistry, chemical engineering, and the life sciences. Headquartered in Philadelphia, with offices in California and Europe, the Institute houses an archive and a library for historians and researchers, a fellowship program for visiting scholars from around the globe, a community of researchers who examine historical and contemporary issues, and an acclaimed museum that is free and open to the public. For more information visit sciencehistory.org. -
Calendario De Mujeres Científicas Y Maestras
Mil Jardines Ciencia y Tecnología Calendario de Mujeres Científicas y Maestras Hipatia [Jules Maurice Gaspard (1862–1919)] Por Antonio Clemente Colino Pérez [Contacto: [email protected]] CIENCIA Y TECNOLOGÍA Mil Jardines . - Calendario de Mujeres Científicas y Maestras - . 1 – ENERO Marie-Louise Lachapelle (Francia, 1769-1821), jefe de obstetricia en el Hôtel-Dieu de París, el hospital más antiguo de París. Publicó libros sobre la anatomía de la mujer, ginecología y obstetricia. Contraria al uso de fórceps, escribió Pratique des accouchements, y promovió los partos naturales. https://translate.google.es/translate?hl=es&sl=ca&u=https://ca.wikipedia.org/wiki/Marie-Louise_Lachapelle&prev=search Jane Haldiman Marcet (Londres, 1769-1858), divulgadora científica que escribió sobre química, enero 1 botánica, religión, economía y gramática. Publicó Conversations on Chemistry, con seudónimo masculino en 1805, pero no fue descubierta su autoría hasta 1837. https://lacienciaseacercaalcole.wordpress.com/2017/01/23/chicas-de-calendario-enero-primera-parte/ https://mujeresconciencia.com/2015/08/19/michael-faraday-y-jane-marcet-la-asimov-del-xix/ Montserrat Soliva Torrentó (Lérida, 1943-2019), doctora en ciencias químicas. https://es.wikipedia.org/wiki/Montserrat_Soliva_Torrent%C3%B3 Florence Lawrence (Canadá, 1886-1938), actriz del cine mudo apasionada por los coches, que inventó el intermitente, pero no lo consideró como propio y pasó el final de sus días sola y arruinada. https://www.motorpasion.com/espaciotoyota/el-dia-que-una-mujer-invento-el-intermitente-y-la-luz-de-freno-para-acabar-despues- arruinada Tewhida Ben Sheikh (Túnez, 1909-2010), primera mujer musulmana en convertirse en medica y llegó a plantear temas como la planificación familiar, la anticoncepción y el aborto en su época, en el norte enero 2 de Africa. -
Commencement1976.Pdf (4.717Mb)
1976 Digitized by the Internet Archive in 2012 with funding from LYRASIS Members and Sloan Foundation http://archive.org/details/commencement1976 ORDER OF PROCESSION MARSHALS STANLEY CORRSIN JOHN W. GRYDER MATTHEW A. CRENSON WILLIAM H. HUGGINS ELAINE C. DAVIS ROBERT A. LYSTAD HANS GOEDICKE EVANGELOS N. MOUDRIANAKIS ARCHIE GOLDEN EVERETT SCHILLER GERALD S. GOTTERER JOHN P. YOUNG THE GRADUATES MARSHALS ROBERT B. POND OREST RANUM THE DEANS MEMBERS OF THE SOCIETY OF SCHOLARS OFFICERS OF THE UNIVERSITY THE TRUSTEES * MARSHALS BROWN L. MURR FRANCIS E. ROURKE THE FACULTIES * CHIEF MARSHAL RICHARD A. MACKSEY THE CHAPLAINS THE RECIPIENT OF THE MILTON STOVER EISENHOWER MEDAL FOR DISTINGUISHED SERVICE THE PRESENTOR OF THE RECIPIENT OF THE MILTON STOVER EISENHOWER MEDAL FOR DISTINGUISHED SERVICE THE HONORARY DEGREE CANDIDATES THE PROVOST OF THE UNIVERSITY THE PRESIDENT EMERITUS OF THE UNIVERSITY THE CHAIRMAN OF THE BOARD OF TRUSTEES THE PRESIDENT OF THE UNIVERSITY ORDER OF EVENTS STEVEN MULLER President of the University, presiding * * * FANFARE PROCESSIONAL The audience is requested to stand as the Academic Procession moves into the area and to remain standing after the Invocation. " " Earle of Oxford's Marche William Byrd The Peabody Wind Ensemble Richard Higgins, Director * INVOCATION REV. CHESTER WICKWIRE Chaplain, The Johns Hopkins University THE NATIONAL ANTHEM GREETINGS ROBERT D. H. HARVEY Chairman of the Board of Trustees PRESENTATION OF THE RECIPIENT FOR THE MILTON STOVER EISENHOWER MEDAL FOR DISTINGUISHED SERVICE HELEN B. TAUSSIG PRESENTED BY RICHARD S. ROSS Vice President for the Health Divisions and Dean, School of Medicine * PRESENTATION OF NEW MEMBERS OF THE SOCIETY OF SCHOLARS LEROY E. -
SUMMARY of PERSONNEL ACTIONS REGENTS AGENDA June 2012
SUMMARY OF PERSONNEL ACTIONS REGENTS AGENDA June 2012 ANN ARBOR CAMPUS 1. Recommendations for approval of new appointments and promotions for regular associate and full professor ranks, with tenure. (1) Boehman, André L., professor of mechanical engineering, with tenure, College of Engineering, effective September 1, 2012. (2) Davenport, Christian, professor of political science, with tenure, College of Literature, Science, and the Arts, effective September 1, 2012. (3) Denton, Brian T., associate professor of industrial and operations engineering, with tenure, College of Engineering, effective September 1, 2012. (4) Fenstermaker, Sarah, professor of women’s studies, with tenure, College of Literature, Science, and the Arts, effective September 1, 2012. (5) Gold, David, associate professor of English language and literature, with tenure, College of Literature, Science, and the Arts, effective September 1, 2012. (6) Mihalcea, Rada F., associate professor of electrical engineering and computer science, with tenure, College of Engineering, effective September 1, 2013. (7) Neumar, Robert W., M.D., Ph.D., professor of emergency medicine, with tenure, effective July 1, 2012, and chair, Department of Emergency Medicine, Medical School, effective July 1, 2012 through June 30, 2017. (8) Ward, Brent B., promotion to associate professor of dentistry, with tenure, School of Dentistry, effective September 1, 2012 (currently assistant professor of dentistry.) 2. Recommendations for approval of new appointments and promotions for regular associate and full professor ranks, without tenure. (1) Abbott, Patricia, associate professor of nursing, without tenure, School of Nursing, effective September 1, 2012. 3. Recommendations for approval of reappointments of regular instructional staff and selected administrative/professional staff. (1) Appelman, Henry D., M.D., M.R. -
Rutheniumarene Complexes of Curcumin
Article pubs.acs.org/jmc Ruthenium−Arene Complexes of Curcumin: X-Ray and Density Functional Theory Structure, Synthesis, and Spectroscopic Characterization, in Vitro Antitumor Activity, and DNA Docking Studies of (p-Cymene)Ru(curcuminato)chloro Francesco Caruso,*,† Miriam Rossi,*,‡ Aidan Benson,‡ Cristian Opazo,§ Daniel Freedman,∥ Elena Monti,⊥ Marzia Bruna Gariboldi,⊥ Jodi Shaulky,# Fabio Marchetti,▽ Riccardo Pettinari,○ and Claudio Pettinari○ † Istituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, c/o University of Rome “La Sapienza”, Istituto Chimico, Piazzale Aldo Moro 5, 00185, Rome, Italy ‡ Vassar College, Department of Chemistry, Poughkeepsie, New York 12604, United States § Vassar College, Academic Computing Service, Poughkeepsie, New York 12604, United States ∥ State University of New York, Department of Chemistry, New Paltz, New York 12561, United States ⊥ University of Insubria, Department of Structural and Functional Biology, Via A. da Giussano 10, 21052 Busto Arsizio, Varese, Italy # Accelrys, Inc., 10188 Telesis Court, Suite 100, San Diego, California 92121, United States ▽ School of Science and Technology, Universitàdegli Studi di Camerino, via S. Agostino 1, 62032 Camerino MC, Italy ○ School of Pharmacy, Universitàdegli Studi di Camerino, via S. Agostino 1, 62032 Camerino MC, Italy *S Supporting Information ABSTRACT: The in vitro antiproliferative activity of the title compound on five tumor cell lines shows preference for the colon−rectal tumor μ μ HCT116, IC50 = 13.98 M, followed by breast MCF7 (19.58 M) and ovarian A2780 (23.38 μM) cell lines; human glioblastoma U-87 and lung carcinoma A549 are less sensitive. A commercial curcumin reagent, also containing demethoxy and bis-demethoxy curcumin, was used to synthesize the title compound, and so (p-cymene)Ru(demethoxy- curcuminato)chloro was also isolated and chemically characterized. -
Read the Full PDF
The Science on Women and Science The Science on Women and Science Christina Hoff Sommers Editor The AEI Press Publisher for the American Enterprise Institute WASHINGTON, D.C. Distributed to the Trade by National Book Network, 15200 NBN Way, Blue Ridge Summit, PA 17214. To order call toll free 1-800-462-6420 or 1-717-794-3800. For all other inquiries please contact the AEI Press, 1150 Seventeenth Street, N.W., Washington, D.C. 20036 or call 1-800-862-5801. Library of Congress Cataloging-in-Publication Data The science on women and science / Christina Hoff Sommers, editor. p. cm. Includes bibliographical references. ISBN-13: 978-0-8447-4281-6 ISBN-10: 0-8447-4281-3 1. Women in science. 2. Sex discrimination against women. 3. Sex differences in education. I. Sommers, Christina Hoff. Q130.S364 2009 2009022004 13 12 11 10 09 1 2 3 4 5 © 2009 by the American Enterprise Institute for Public Policy Research, Washington, D.C. All rights reserved. No part of this publication may be used or reproduced in any manner whatsoever without permission in writing from the American Enterprise Institute except in the case of brief quotations embodied in news articles, critical articles, or reviews. The views expressed in the publications of the American Enterprise Institute are those of the authors and do not necessarily reflect the views of the staff, advisory panels, officers, or trustees of AEI. Printed in the United States of America Contents INTRODUCTION: THE SCIENCE ON WOMEN IN SCIENCE, Christina Hoff Sommers 1 Notes 5 References 6 1WHY SO FEW WOMEN IN MATH AND SCIENCE? Simon Baron-Cohen 7 Sex Differences in the General Population 11 Female Advantage in Empathy 15 Culture and Biology 18 Conclusions 18 Notes 20 References 21 2GENDER, MATH, AND SCIENCE, Elizabeth S.