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Download Biozoom NO. 2 2018 VOLUME 20 DANISH SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY – WWW.BIOKEMI.ORG Din partner inden for salg, service og kalibrering af laboratorie- og pipetteringsudstyr Nyt automatiseringsinstrument fra Integra Viaflo Med Assist Plus bliver rutine pipetterings- opgaver lettere og ensartet • Features som: • Fyldning af plader • Fortyningsrækker • Plader fra 12 til 384 brønde • Automatisk spidspåsætning • Automatisk spidsafskydning • Racks til forskellige rør • Programmering via PC Assist Plus er tilgængelig på det danske marked fra november 2018. Ønsker du flere informationer eller bestille tid til en demo, så kontakt os allerede nu. Skriv til Kirsten Thuesen [email protected] Saml dine akkrediterede kalibreringer af vægte og pipetter hos os DANAK har godkendt Dandiag (Reg. nr. 490) til at udføre akkrediterede kalibreringer af laboratorie vægte fra 1 mg og optil 72 kg. Det betyder, at vi nu kan tilbyde dig, at stå for dine akkrediterede kalibreringer på dine vægte og pipetter. For dig betyder det, at du kun behøver at ringe ét sted, når du skal bruge hjælp til at få foretaget disse kalibreringer. Så ønsker du en høj præcision eller skal I auditeres, har du fordele ved at anvende os. Det er nu nemt, trygt og oplagt at samle dine bestillinger her, hvor du kender kvaliteten som Dandiag står for. Har du brug for at spare tid, så bestil dine vægte og pipetter med en akkrediteret kalibrering. Med et kalibreringscertifikat fra Dandiag får du en garanti for, at dit udstyr er kalibreret i henhold til ISO 8655 (pipetter) og ISO 17025, hvilket kan bruges i forhold til dine egne krav. Dandiag A/S Baldershøj 19 DK-2635 Ishøj Tlf. +45 4343 3057 www.dandiag.dk [email protected] Din partner inden for salg, service og BioZoom BioZoom Medlemsblad for Biokemisk Forening. kalibrering af laboratorie- og pipetteringsudstyr BioZoom er en uafhængig kvartårlig publi- kation. Artikler giver udtryk for forfatternes egne holdninger og ikke redaktionens. Forfat- terne har copyright og artikler kan gengives med angivelse af kilde. Nyt automatiseringsinstrument Redaktion Helene Halkjær Jensen TEMA: Nobel-satsning i dansk forskning Postdoc fra Integra Viaflo Department of Chemistry and Bioscience Biotechnology Aalborg University Leder: Mod stjernerne Med Assist Plus bliver rutine pipetterings- Fredrik Bajers Vej 7H DK-9220 Aalborg HELENE HALKJÆR JENSEN, [email protected], OG STEEN GAMMELTOFT, opgaver lettere og ensartet E-mail: [email protected] [email protected], REDAKTØRER, BIOZOOM 4 Mette Vixø Vistesen How to win a science Nobel Prize Unit of Cell Stress and Survival • Features som: MATS LARSSON, MEMBER OF THE NOBEL COMMITTEE FOR PHYSICS AND THE ROYAL SWEDISH Center for Autophagy, Recycling and Disease ACADEMY OF SCIENCES, PROFESSOR IN CHEMICAL PHYSICS, AND DIRECTOR OF • Fyldning af plader Danish Cancer Society Research Center ALBANOVA UNIVERSITY CENTRE, STOCKHOLM UNIVERSITY, SWEDEN. [email protected] Strandboulevarden 49 6 • Fortyningsrækker DK-2100 Copenhagen • Plader fra 12 til 384 brønde E-mail: [email protected] Det danske ’Nobel-center’: en overvældende satsning • Automatisk spidspåsætning INTERVIEW MED KRISTIAN HELIN, LEDER AF BRIC, KU. Steen Gammeltoft HELENE HALKJÆR JENSEN, REDAKTØR, BIOZOOM, [email protected] 9 • Automatisk spidsafskydning Hellerupvej 8, 4tv DK-2900 Hellerup • Racks til forskellige rør E-mail: [email protected] Den rette person og den gode idé INTERVIEW MED THOMAS SINKJÆR, FORSKNINGSDIREKTØR, LUNDBECKFONDEN. • Programmering via PC Indlæg sendes til redaktionen HELENE HALKJÆR JENSEN, REDAKTØR, BIOZOOM, [email protected] 12 Steen Gammeltoft Hellerupvej 8, 4tv Danmark i forskningens verdenselite Assist Plus er tilgængelig på det danske marked fra november 2018. DK-2900 Hellerup E-mail: [email protected] SIMON GLERUP, LEKTOR, PH.D., INSTITUT FOR BIOMEDICIN, AARHUS UNIVERSITET. Ønsker du flere informationer eller bestille tid til en demo, så kontakt os allerede nu. [email protected] 16 Skriv til Kirsten Thuesen [email protected] Abonnement på BioZoom Pris 300 kr. per år. Udsendes til alle medlem- Nyt fra Biokemisk Forening mer af Biokemisk Forening. Abonnementsteg- ning og indmeldelse kan ske på foreningens METTE VIXØ VISTESEN, BESTYRELSESFORMAND FOR BIOKEMISK FORENING, PH.D.-STUDERENDE VED GRUPPEN FOR CELLESTRESS OG OVERLEVELSE, KRÆFTENS BEKÆMPELSES FORSKNINGS- website: www.biokemi.org Saml dine akkrediterede kalibreringer CENTER. [email protected] 19 Udgiver: af vægte og pipetter hos os Vabø Publishing ApS Stationsparken 24 FORSIDE: 2600 Glostrup DANAK har godkendt Dandiag (Reg. nr. 490) til at udføre akkrediterede kalibreringer af laboratorie Alfred Nobel på et antik tryk fra 1899. Efter G. Flormann og udgivet i det 19. århundrede i portrætter, Tlf. 39 90 80 00 Tyskland. vægte fra 1 mg og optil 72 kg. Det betyder, at vi nu kan tilbyde dig, at stå for dine akkrediterede www.scanpublisher.dk Alfred Nobel (21. oktober, 1833 – 10. december, 1896) var en svensk kemiker, ingeniør, opfinder, kalibreringer på dine vægte og pipetter. For dig betyder det, at du kun behøver at ringe ét sted, ISSN 1398-0823 forretningsmand og filantrop. Nobel ejede Bofors, som han havde udviklet fra sin tidligere rolle som primært en jern- og stålproducent til en stor producent af kanoner og andre våben. Nobel havde 355 når du skal bruge hjælp til at få foretaget disse kalibreringer. Så ønsker du en høj præcision eller E-udgave af BioZoom forskellige patenter, hvor dynamit er det mest berømte. Da Alfred Nobel’s testamente blev åbnet, kom skal I auditeres, har du fordele ved at anvende os. Artikler i BioZoom kan læses i arkivet på det som en overraskelse, at hans formue skulle bruges til priser i fysik, kemi, fysiologi eller medicin, www.biokemi.org og www.danskbiotek.info litteratur og fred. Nobelfonden blev oprettet i 1900 til at forvalte de økonomiske midler, der er til rådighed for den årlige tildeling af de fem Nobelpriser. https://www.nobelprize.org/alfred_nobel/biographical/ Det er nu nemt, trygt og oplagt at samle dine Annoncer articles/life-work/ bestillinger her, hvor du kender kvaliteten Niels Rudolfsen E-mail: [email protected] som Dandiag står for. Tlf.: 39 48 51 08 www.danskbiotek.info Besøg Har du brug for at spare tid, så bestil dine vægte og pipetter med en akkrediteret Biokemisk Forening Sekretær: Vivian Dyrup Juhl, [email protected] kalibrering. Med et kalibreringscertifikat Formand: Mette Vixø Vistesen, fra Dandiag får du en garanti for, at dit [email protected] udstyr er kalibreret i henhold til ISO 8655 Layout og tryk: (pipetter) og ISO 17025, hvilket kan bruges Stibo Complete i forhold til dine egne krav. www.cotedor.dk Copyright BioZoom 2014 Dandiag A/S Baldershøj 19 DK-2635 Ishøj Tlf. +45 4343 3057 www.dandiag.dk [email protected] BIOZOOM 2 3 BioZoom LEDER: Mod stjernerne HELENE HALKJÆR JENSEN, [email protected], OG STEEN GAMMELTOFT, [email protected], REDAKTØRER, BIOZOOM Hvis man skal nævne én institution siteter er åbenlyst stolte af deres mange sen i litteratur rystet af skandalehistorier, inden for viden og videnskab, som de Nobelpristagere og skilter med det på som er blæst ud i mediemøllen (2). Det fleste kender, ligger Nobelprisen højt på deres hjemmesider. Dansk forskning har stærke image krakelerede. Det er en listen. Som en anerkendt blåstempling kun modtaget to Nobel priser i de sidste paradoksal illustration af, hvor vigtig en af et forskningsområde eller en opda- 25 år ud af i alt 9 priser i Nobelprisens position, Nobelprisen har fået på ver- gelse har Nobelprisen fået karakter af 116-årige historie. For den sidste pris densplan. Det Svenske Akademi blev en golden standard for den ultimative vedkommende blev den banebrydende grundlagt i 1786 af den svenske kong forskning og nybrud (1). Hvert år i den opdagelse gjort for 60 år siden i Aarhus Gustav III. Akademiet består af 18 med- første uge af oktober venter vi med af Jens Christian Skou. lemmer, hvis embedsperiode er for livet. spænding på offentliggørelsen af årets Det var en periode, der kunne be- Kendt som ”de atten” omfatter akade- tre Nobelpriser i fysik, kemi, og fysiologi tegnes som dansk naturvidenskabelig miets medlemmer anerkendte svenske eller medicin. Det er en festlig uge med forsknings guldalder. Forskningen var forfattere, lingvister, litteraturforskere, billeder af overraskede og glade for- koncentreret på fire universiteter og et historikere og en fremtrædende jurist. skere, omtale i nyhedsmedierne, kom- par private forskningsinstitutter. Inden Dets arbejdsorgan er Nobelkomitéen, mentarer fra andre forskere og analyser for naturvidenskab var forskningen præ- som består af seks medlemmer, udvalgt i fagtidsskrifter. I mere end 100 år er get af flere store personligheder, bl.a. blandt ”de atten” for en treårig periode Nobelprisen uddelt til forskere, som har August Krogh, Kaj Linderstrøm-Lang (3). bidraget med banebrydende opdagelser og Ole Maaløe, som var internationalt Den 4. maj 2018 udsendte Nobel- inden for natur- og lægevidenskab. anerkendte og tiltrak forskere fra udlan- fonden en pressemeddelelse, at det Siden prisen uddeltes for første gang det. Forskningen var samlet om enkelte Svenske Akademi ikke vil udpege en i 1901, er amerikanske forskere løbet fremtrædende forskere, som havde den modtager af Nobelprisen i litteratur i med hovedparten af priserne. Nobel- nødvendige originalitet, engagement, 2018, og at uddelingen er udsat til 2019. priserne er et af kendemærkerne for udsyn og produktivitet (Figur 1). Beslutningen skyldes en skandale inden amerikansk forsknings førende position i I 2018 blev grunden under Det Sven- for egne rækker – en ”sexmisbrug” verden. De bedste amerikanske univer- ske Akademi og uddelingen af Nobelpri- skandale, selvom det saftige udtryk Figur 1: Synergien af gode idéer og dygtige forskere kan give store resultater. Her ses i 1950 Ole Maaløe i midten med pibe. Ole Maaløe var læge og moleky- lærbiolog og bidrog signifikant til forståelsen af bakteriel fysiologi og syntesen af DNA, RNA og protein. Stående bagest er Niels Kaj Jerne, som studerede antistoffer. Han var med til at opdage pricippet bag monoklonale antistoffer og fik Nobelprisen for sit arbejde i 1984. Foran Jerne sidder James Watson, som var med til at bestemme dob- belt helix-strukturen af DNA og fik Nobelprisen i 1962.
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