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Home , Buddleja macrostachya, Camellia taliensis, Chen Da (sociologist), Chen Da (Water Margin), Chen Gang (born 1966), Chen Jin (actress)

CONTENT

1.MESSAGE FROM DIRECTOR …………………………………………………………………………………………………………………………………………………… 03 2.ORGANIZATION STRUCTURE …………………………………………………………………………………………………………………………………………………… 05 3.HIGHLIGHTS OF ACHIEVEMENTS …………………………………………………………………………………………………………………………………………… 06 Coexistence of Conserve and Research----“The Germplasm Bank of Wild ” services biodiversity protection and socio-economic development ………………………………………………………………………………………………………………………………………………… 06 The Structure, Activity and New Drug Pre-Clinical Research of Monoterpene Indole Alkaloids ………………………………………… 09 Anti-Cancer Constituents in the Herb Medicine-Shengma (Cimicifuga L) ……………………………………………………………………………… 10 Floristic Study on the Seed of Yaoshan Mountain in Northeast …………………………………………………………………… 11 Higher Fungi Resources and Chemical Composition in Alpine and Sub-alpine Regions in Southwest ……………………… 12 Research Progress on Natural Tobacco Mosaic Virus (TMV) Inhibitors…………………………………………………………………………………… 13 Predicting Global Change through Reconstruction Research of Paleoclimate………………………………………………………………………… 14 Chemical Composition of a traditional Chinese medicine-Swertia mileensis……………………………………………………………………………… 15 Mountain Ecosystem Research has Made New Progress ………………………………………………………………………………………………………… 16 Cyclic Peptide has Made Important Progress ………………………………………………………………………………………………………………… 17 Progresses in Computational Chemistry Research ………………………………………………………………………………………………………………… 18 New Progress in the Total Synthesis of Natural Products ……………………………………………………………………………………………………… 19 New Progress on the Ecological Function Research of Plant Secondary Metabolites …………………………………………………………… 20 The Chemical Research of Obtained New Progress ……………………………………………………………………………………………………… 21 Successfully Propagating and Ex Conserving the Critically Endangered Plants ……………………………………………………………… 22 The Research of Planting “Golden Oriole” Promoted the Development of Yunnan Flower Industry …………………………………… 23 4.ACHIEVEMENTS AND AWARDS ………………………………………………………………………………………………………………………………………………… 24 "Compilation of Reipublicae Popularis Sinicae " won the first prize of 2009 China's State Natural Science Award …… 24 KIB Wins the Title of "Outstanding Unit" in 10th Anniversary of Sci-tech & Industrial Base for Traditional Chinese Medicine (TCM) Modernization, and Academician ZHOU Jun et al Awarded as "Advanced Individuals" …………………………… 26 Professor Ji-Kai Wins 2nd TAN Jia-Zhen Bioscience Innovation Award …………………………………………………………………………… 26 Study of Alpine Plant Diversity ………………………………………………………………………………………………………………………………………………… 27 A Study on Novel-structured Alkaloids from ………………………………………………………………………………………………… 28 Investigation, Research & Protection of Spermatophyte Diversity in Southeast Yunnan & Adjacent Areas ………………………… 29 A Study on Plant Origin, Material Basis, Quality Evaluation System & Secondary Fermentation Technique of Puerh …… 30 5.SCIENTIFIC PUBLICATIONS AND PATENT APPLICATION …………………………………………………………………………………………………………… 31 6.NEW AND ONGOING NATIONAL RESEARCH PROJECTS…………………………………………………………………………………………………………… 31 7.INTERNATIONAL COOPERATION AND REGIONAL EXCHANGES ……………………………………………………………………………………………… 33 Overview of International and Regional Cooperation …………………………………………………………………………………………………………… 33 The First Forest Seeds from ICRAF is Reserved in the Germplasm Bank of Wild Species …………………………………………………… 33 Comprehensive Survey of Plant Diversity in Hengduan Mountain Area Completed and Gained Significant Results…………… 33 2009 Annual Conference of Swedish Environment Secretariat in Successfully Held …………………………………………………… 34 First "Foreign Young Scientist Program" is Approved……………………………………………………………………………………………………………… 34 Talents Cultivation & Introduction through International Cooperation…………………………………………………………………………………… 34 China Project Seminar of Botanic Gardens Conservation Internationa l………………………………………………………………………………… 35 Cooperation with Enterprises…………………………………………………………………………………………………………………………………………………… 35 Transformation of New Flower Cultivars…………………………………………………………………………………………………………………………………… 35 Creation & Transformation of New Medicine …………………………………………………………………………………………………………………………… 35 Management of Joint-stock Companies …………………………………………………………………………………………………………………………………… 35 8.CONSTRUCTION OF TALENTS TEAM AND SCIENTIFIC RESEARCH PLANTPORMS …………………………………………………………………… 36 Construction of Talents Team Proceeded ………………………………………………………………………………………………………………………………… 36 Construction of Platforms for Scientific Research …………………………………………………………………………………………………………………… 38 IMPORTANT EVENTS 2009 ………………………………………………………………………………………………………………………………………………………… 41 APPENDIX 1 STAFF AND STUDENTS ………………………………………………………………………………………………………………………………………… 52 APPENDIX 2 LIST OF PUBLICATIONS ………………………………………………………………………………………………………………………………………… 61 APPENDIX 3 LIST OF PATENTS GRANTED AND APPLIED ………………………………………………………………………………………………………… 83

2 1. MESSAGE FROM DIRECTOR

2009 is a meaningful year to every Chinese citizen. translations. We celebrate the 60th anniversary of the founding of In administrative construction and innovative our great motherland, and the 60th anniversary of the construction, KIB persists in practicing "Standard founding of Chinese Academy of Sciences (CAS). During Implementation", and has made remarkable results in 2009, Institute of (KIB) has made great carrying out public affair administration standard. Official process in the areas of construction and development as documents and archives have successfully passed the A-level well as scientific research and study. In terms of scientific standard appraisal of CAS. research tasks, KIB has undertaken 1 candidate project The "Yue-Sai Rhododensron Garden" is under smooth of state high-tech development program; 22 NSFC construction. " & Azalea Collection & Optimization", projects (thereinto 1 key project, 2 NSFC-Yunnan Province which has been discussed and proved by specialists, will key joint projects and 1 major research program); 10 be put into construction in June. Youth Apartment and scientific & technological programs of Yunnan Province Visitors Apartment, after acceptance inspection, have been (thereinto 2 major projects and 1 "Strengthening Yunnan put into use. "The Germplasm Bank of Wild Species", a through Science & Technology" project), 1 innovation national major scientific program, has reached the academic team of Yunnan Province, 1 top talents program of Yunnan goal and has passed the professional construction safety Province, 3 reserve talents programs of Yunnan Province acceptance inspection and pre-inspection respectively and 2 national research projects of new medicine; 21 organized by Finance & Accounting Bureau of CAS and CAS. CAS programs (including 1 open research project of large Finally, in November, the whole project has passed the scientific facilities and 1 young foreign scientist program); acceptance inspection of National Development and Reform and has newly signed 11 international cooperation Commission (NDRC) and is highly praised by specialists. programs, 18 entrust projects. The total expenditure of new Moreover, the database reverses the first batch of seeds projects and programs has been over RMB 80,000,000. KIB from ICRAF. Kunming Botanical Garden is first batch of has also taken part in constructing the southwest strategic "Education Base of Three 'L's (Loving life, Learning to biological resources supercomputing sub-center and survive and Living happily)". regional biodiversity large-scale equipment center. Besides, During 2009, there are 289 candidates including 136 26 national invention patent applications, 9 national doctorial candidates. The first foreign postdoctor has invention patent authorizations, 1 USA patent granting and completed the thesis defense in September and successfully 2 trademark registration certificates have been achieved finished curriculums. Up to now, 2 doctorial dissertations through the effort of KIB staff. KIB has formed and are selected as national distinguished doctorial paper and registered 5 scientific achievements, and has applied for 4 3 doctorial dissertations as CAS distinguished doctorial provincial scientific awards including 2 first prizes in Natural papers. 7 doctorial candidates are granted with 2009 CAS Science Award, 2 second prizes and Tan Jiazhen Bioscience President Outstanding Award and 10 candidates are given Innovation Award won by -Kai, a researcher in 2009 CAS Title Award. Besides, KIB has employed 7 foreign KIB. Throughout 2009, by conducting talent introduction experts who are devoted to full-time scientific research or scheme, the institution has recruited 2 new talents. project management. With the help of "Foreign Technology Additionally, 2 researchers have been selected in "100 & Talents Introduction Project" proposed by Bureau of Talents" program; another 2 researchers are now applying Foreign Experts Affairs, Yunnan Province, mycology experts for "100 Talents" program; and 1 researcher has been from New Zealand conduct a three months joint-study which selected in hi-tech talents introduction scheme of Yunnan obtains significant achievements in endangering risks and Province. As for management, KIB has accomplished artificial cultivation of truffle planted in Yunnan Province. the change of institute-level leaders and the position Besides, KIB, together with Buea University of Cameroon, adjustment of in-between leaders. In respect of the quality jointly educates 1 doctor through the CAS-TWAS Scholarship and quantity of academic articles and papers, KIB has come Program. a long way. In total, there are 258 SCI articles thereinto 44 articles are related to 15% frontier science of JCR and 82 articles related to 30%, and 5 volumes of monographs and

3 Many scholars and researcher from universities or academic institutes, including Australian Academy of Science, Griffith University, Tasmanian Botanical Gardens, BGCI, British Columbia University, Royal Botanic Gardens, Kew, Royal Botanic Garden Edinburgh, Flora and Fauna International, Tribhuvan University of Nepal, Bergen University of Norway, University of Michigan, University of , University of Chicago, Duke University, Ohio State University, Longwood Gardens, etc. Their active communication with researchers on scientific research and experiences also further develops KIB's foreign exchange affairs. KIB also carries out academic communication and exchanges with Institute of Biochemistry and Cell Biology, CAS and Institute of Health Science, CAS. , Vice Chairman of CPPCC, Chairman of China Public Interest Party and Minister of Ministry of Science and Technology (MOST); BAI Chun- Executive Vice-president and Deputy Secretary of Party Committee of CAS; ZHANG Xiao- Qiang, Vice Director of National Development and Reform Committee (NDRC); SHI Er-, LI Jia-Yang and ZHAN Wen- Long, Vice President of CAS; FANG Xin, Deputy Secretary of Party Committee of CAS; Yi-Yu, President of National Natural Science Foundation of China (NSFC); HE Duan-, Vice Governor of Yunnan Provincial Government; - Gang, Secretary of CAS; TAN Tie-Niu, Vice Secretary of CAS have carried out an investigation in KIB and conducted an inspection visit to " The Germplasm Bank of Wild Species", state key laboratory of phytochemistry, and key laboratory of biodiversity and biogeography of CAS and Kunming Botanic Garden. They highly appreciate all the achievements made by KIB in applying Scientific Outlook on Development and implementing Knowledge Innovation Program (KIP). Dreams are always extending whilst footsteps are consistently steadfast. A new year brings a new prospective and new goals provide everyone with inspiration. With magnificent oath and endless endeavor, KIB will persistently forge ahead with reformation and innovation.

Spring 2010

4 2. ORGANIZATION STRUCTURE

5 3. HIGHLIGHTS OF ACHIEVEMENTS Coexistence of Conserve and Research“The Germplasm Bank of Wild Species”services biodiversity protection and socio-economic development

China is one of the countries which have the most abundant biological germplasm resources in the world. For a long time, due to the pressure of huge population and the deterioration of ecological environment, the biodiversity of China suffered serious threats. Meanwhile, many other countries are collecting China’s biological species using various means and preemptively registering patents on the basis of further research, which generate a “strange phenomena” insofar that we have to pay for the patent fee to America if planting Chinese . is not only the most biologically diverse areas, but also one of the important areas within which there is a concentration of biological germplasm resources the surrounding areas into consideration. Mostly, collections in the world. In August 1999, CAS Academician WU - focus on rare and endangered species, endemic species Yi suggested to construct a germplasm bank of wild and the species with important economic and scientific species and in 2004 the National Development an Reform value. In the 5 years of construction, the germplasm bank Commission listed the germplasm bank of wild species as a was designed, manufactured and installed according to major national science project. Since 2004, “The Germplasm the internationally recognized standards of plant seed Bank of Wild Species in Southwest China” (abbreviated as preservation. An example of this is the drying room, Germplasm Bank), assumed by CAS Kunming Institute of which has reached a double-15 standard (15℃ and 15% Botany and co-constructed by Yunnan University and CAS humidity), and contains sufficient space to accommodate Kunming Institute of Zoology, completed the construction relative the massive collection of seed. Other example task on schedule and to a high quality within 5 years and include the refrigeration house which has a constant built facilities for wildlife germplasm preservation which temperature of minus 20℃ and adequate storage space have important international implications, its ability of and the walk-in incubators which have intelligent control preservation reaching the international advanced level. The capabilities within which researchers may enter and initiate germplasm bank provides an important strategic reserve temperature gradient changes. The project also established of biological resources for sustainable economic and social a germplasm resources database and information sharing development in China and its research has produced management system and built a technical system and significant social benefits. research platform with gene function testing, cloning and Relying on resources advantage and aiming at a verification. This has provided an excellent capacity for world-class standard of excellence preserving and researching wild germplasm resources and The germplasm bank mainly focuses on germplasm the facility is rapidly becoming one of the important wild protection of wild species in southwest China, and also takes species germplasm banks in the world. The germplasm

6 bank has been constructed and is operated according to international standards. Organizing the national network, strengthening international cooperation and building an international team During the project construction, we effectively organized a team with 627 persons from 58 universities and research institutions from all around the country and established partnerships with 13 national nature reserves. We have collected and conserved 8444 species, 74641 accessions (strains) germplasm resources of wild species, isolated and identified 12 functional genes, established BAC and YAC bank for each, and reserved 437 species from the wild in products in Yunnan mainly consist of flowers, are the nursery. The project has exceeded the target of species short of pot-grown material, low in species diverstity and collection and conservation during the construction approved often introduced from abroad, KIB is cooperating with by National Development and Reform Commission and it has Yunnan Green Land Bio-Technology Co., Ltd.. Through become another world major program after the construction support from the germplasm bank it has been possible to of UK Millennium Seed Bank.The project attaches great collect resources, screen flower material, analyze genetic importance to international cooperation. In May 2004, we background, breed in size controls and then cultivate a signed 10-year agreement with the UK through the Royal group of new varieties such as Begonia , , Botanic Gardens Kew, entitled: “The Cooperation Agreement Michelia , etc,. This has provided strong on wild plant germplasm conservation and research support to the Green Land Company which was successfully between Chinese Academy of Sciences and the Board of listed in Stock Exchange in December 2007. Trustees of the Royal Botanic Gardens Kew”. In June 2009, Help businesses passing the national high-tech we received 365 samples of seeds from 19 countries enterprise certification by Camellia germplasm that are kept in World Agroforestry Centre. In August 2009, resources. we received another group of 21 samples of tree seeds from As a part of the germplasm bank, KIB’s Camellia Garden 3 countries (India, Kenya, Tanzania ), which symbolized the has a collection of 423 kinds and varieties of camellia plants germplasm bank has grown into an international platform and these are cultivated in an area of some 60 acres, for preservation of germplasm resources. forming the most complete camellia garden in Yunnan and During the construction, we have implemented the talent an important Camellia plant germplasm conservation and strategy-“sending out, bringing in, inviting to come and research and development center in China. In 2008, China instantly training”. We have sent 8 persons to participate substantially increased the certification standards of high- training and exchange in UK Royal Botanic Gardens and tech enterprise. The germplasm bank cooperated with elected 2 doctors to co-train with Millennium Seed Bank of Yunnan Landscape Engineering Co., Ltd., starting the UK’s Royal Botanic Gardens Kew; introduced 4 talents from the core intellectual property, mainly carried out the of CAS “Hundred Talents Program”, set up two 30-member- collection of camellia germplasm in Yunnan, breeding of supported systems, trained and brought up a high-level new varieties, selection of rootstocks and demonstration wildlife germplasm preservation and research team which of seedling breeding technology and scale breeding, etc, is mainly made up of young and middle ages; invited more assisted the enterprise passing the country’s new round of than 20 international professions to take part in the project high-tech enterprise certification. construction; and have training more than 450 people. Participate in national new drug development by The project has constructed a collaborative network and research platform for collecting, preserving, sharing and using germplasm resources as the core and promoted the development of wild germplasm preservation and biodiversity research. Paying equal attention to preservation, research, open and sharing and supporting the development of national bioindustry The project insists on the principle of “constructing, preserving, research, using at the same time” and has played an important role in supporting the development of national bio-industry. Support companies successfully listing by Verbascum germplasm resources. germplasm resources of wild flowers. Gongxuening (developed during the nineteen eighties by Aiming at addressing the issues that the flower KIB) is the preferred drug for gynecological hemorrhagic

7 disease, as approved by Ministry of Health, and has been of ex situ plant conservation” and it was published on included in the national medicine protection list. However, 《Trends in Plant Science 》. The article mainly introduces the manufacture of this drug is subject to problems, the latest situation of plant seed collection and conservation including the fact that the raw material of Chinese herbal in UK Millennium Seed Bank, Southwest China Germplasm medicine-Yunnan Manyleaf Rhizome is endangered Bank of Wild Species, U.S. National Crop Germplasm Bank, and the Hemostatic component content in the root of China National Crop Germplasm Bank and Svalbard Global Yunnan Manyleaf Paris Rhizome is not particularly high. Seed Bank (that is Norway Noah's Ark Seed Bank) as well Research found that some Verbascum plants contain an as the significant meaning for achieving "Global Strategy for Plant Conservation" and ensuring world food security. Since started in 1997, the UK Millennium Seed Bank has achieved the goal of conserving all the plant species in UK and 10% of the plant species in the world. The Germplasm Bank of Wild Species in Southwest China, following the UK Millennium Seed Bank, is another major program of protecting biodiversity and accomplishing global strategy for plant conservation and attracts international attention because of the focus on biodiversity hotspots. The article reviewed global ex situ conservation of plants, especially the research background, scientific issues, action plans and conservation strategies of the seed bank, mainly discussed the challenges and important scientific problems with active ingredient to stop bleeding and therefore, applied which the seed bank will face in protecting plant diversity, for a patent. Some related researches closely linked with especially the issues of seed viability, seed longevity and the germplasm bank, collected and integrated Verbascum cryopreservation. By listing a large number of examples and germplasms, developed the research of resources data, the article further illustrated as one of the key means introduction, cultivation and tissue culture, resulting in of protecting plant diversity, the seed bank is much better Verbascum becoming a substitute of Gongxuening and than in situ conservation and other ex situ conservation emerging as a new drug. methods in capital investment, time and efficiency savings. Support bioindustry by microbial germplasm In conclusion, the article formed analysis and an outlook on resources. the goal and problems of global plant ex situ conservation The germplasm bank collected microbial nematicide and especially emphasized that strengthening the training in Yunnan Plateau (including Nematode-trapping of seed plant and biology talents is an important Hyphomycetes which account for 80% of the national total guarantee for continuously carrying out global plant and 55% of the global total and toxin-production fungi diversity protection. which account for 95% of the nation and 50% of the world), and then on this basis established nematode bio-control resources bank with the most diversified resources and the largest number of samples in the world, and conserved more than 8000 strains microbial nematicide. Through study, we have screened and obtained strains with desirable comprehensive characters, solved the key technology from the nematode bio-control resources to application and developed the Nematodes microbial pesticide that is the first to possess independent intellectual property rights in China. In addition, through achievement in conversion, this has assisted many companies gradually overcome the problemsnof production and begin development. Illuminate the scientific problems and action plan of the conservation of global plant germplasm resources. China contains several world's biodiversity hotspots. These hotspots are rich in biodiversity, and, within China, are facing the tremendous pressure on environment and biodiversity as a result of rapid economic development. Thus, the protection of plant diversity in China has become a worldwide focus. Researcher LI De-Zhu and Professor Hugh Pritchard, from the UK’s Royal Botanic Gardens Kew, co-authored the review article: “The science and economics 8 The Structure, Activity and New Drug Pre-Clinical Research of Monoterpene Indole Alkaloids

Researcher Luo Xiao-Dong and his group have vinblastine-derivatives. Now their mechanism studies and accumulated much experience about the extraction, in vivo pharmacodynamic evaluation are ongoing. In past 5 separation and isolation, structural elucidation of years, they have found total alkaloids in of Alstonia monoterpene indole alkaloids in resent years, and Scholaris are the active part. Additionally, they have finished discovered a series of novel alkaloids including 4 new all pre-clinical studies on the fifth class of new Chinese skeletons published on Organic Letters in 2007, 2008 drugs. Application of the new drugs has passed the on- and 2009. Two of them were introduced by ‘Hot off the site assessment of Food and Drug Administration of Yunnan press’ of Natural Products Reports in 2007 and 2008. He, Province, and was submitted to State Food and Drug with the collaborators found 2 new monoterpene indole Administration and has been formally accepted. In addition, alkaloids with significant anti-tumor activity. The cytotoxic partial results of new drugs research have been published, test against certain tumor cells as well as toxicity test including 10 papers and 4 patents. (LD50 (iv), MTD) in the animal models (rats and mice) indicated both compounds were more significant than

Pierinine Alstonia scholaris

A. yunnanensis Melodinus yunnanensis

9 Anti-Cancer Constituents in the Herb Medicine-Shengma (Cimicifuga L)

Prof. QIU Ming-Hua and his group have isolated and tested compounds, and established the testing methods and identified 164 compounds, including 40 new constituents, quality control standards for crud drugs, its extracts, active 2 of which have novel skeleton, from six samples which fractions and active compounds. In addition, they assessed are the rhizome of Cimicifuga foetida L and Cimicifuga the inhibitory effect of 14 triterpenoids on human drug yunnanensis H collected from Dali, in Yunnan and resistant breast cancer cells and found that compounds Weining in . Cooperating with Kunming Medical KCY14, KCY49 and KYY20 had potent activities, with IC50 College, the group tested those compounds’ cytotoxicities values of 5.29, 4.81 and 4.81μg/ml, respectively, which against different human cell lines and found that compounds were as equal as the positive control TAXOL (IC50 4.81μg/ K-5, K-6, K-314 and DK-314 showed significant activities. ml). The research applied for 6 national invention patents The vivo activities of K-314 and DK-314 have been tested and 4 were authorized, published 10 academic papers on the mice and nude mice models and the results showed and nine were in SCI. They have trained 4 doctors and 4 that these two compounds can significantly inhibited the masters. growth of solid tumors and are potential anticancer drugs. The group also explored the preliminarily technology of the preparation and the structure-activity relationships of the

In fluence of Actein and Deoxyactein on the growth of In fluence of Actein and Deoxyactein on the growth of mice transplanted Sarcoma S180 Human hepatocellular carcinoma Bel-7420 Xenografts in nude mice

Cimicifuga foetida Cimicifuga foetida

10 Floristic Study on the Seed Plants of Yaoshan Mountain in Northeast Yunnan

Yaoshan Mountain, the cordillera that Wumeng Mountains plant specimens of Yaoshan Mountain in KIB herbarium to extends to the northeast, located in of a larger extent, but also deepened the understanding of northeast Yunnan, which is on the edge of , the composition, characteristics, origin and evolution of the Yunnan and Guizhou along Jinshajiang valley. In terms of flora in the region. “Checklist of Seed Plants of Yaoshan floristic regions, it belongs to the combining zone of Sino- Mountain, WE Yunnan” was published by the Yunnan Science Himalayan forest sub-subkingdom and Sino-Japanese and Technology Press. forest sub-subkingdom, between and Yunnan Plateau. Due to its long land history, diverse landscape and rich components of old and transitional flora, it becomes one of the key areas that contact the three major distribution centers of endemic genera of seed plants in China (Eastern Sichuan-western ; Yunnan, Guizhou and ; and Henduan mountains). Since 2002, the research team, led by Researcher WANG Hong of KIB and under the fund support of the platform project of Ministry of Science and Technology and National Natural Science Foundation, carried out several large-scale investigations and the collection of seed plants in Yaoshan Mountain National Nature Reserve throughout different seasons over a period of six years. They have arranged the seed plants in accordance with “Angiosperm Phylogeny Group II”(APG II)system, and identified a total of 163 families, 809 genera, 2366 species of seed plants, including Medicine Mountain Vegetation landscape nine East Asia families, two Chinese endemic families, 27 Chinese endemic genera and 1096 Chinese endemic species (including 16 endemic species in local narrow domain). The new taxa found in Yaoshan Mountain are Pedicularis yaoshanensis , Paris stigmatosa, Cremastra appendiculata, Rhododendron qiaojiaense and R. yaoshanense . They mainly researched the pollination ecology and conservation biology of several endemic orchid species in core and edge region of Yaoshan Mountain National Nature Reserve and proposed reasonable suggestions for species protection. Meanwhile, they presented more than 500 collections of plant seeds from Yaoshan Mountain to the germplasm bank. This work not only enriched the collection and preservation of seed Cypripedium tibeticum

Rhododendron yaoshanense R. qiaojiaense

11 Higher Fungi Resources and Chemical Composition in Alpine and Sub-alpine Regions in Southwest China

On the basis of abundant field investigation, researchers novel structure, and then screened the anti-tumor, anti- YANG Zhu-Liang, LIU Pei-Gui, LIU Ji-Kai and their team HIV-1 and metabolic disease activity of these components, collected 5300 specimens, more than 1290 strains, more finding 5 with more significant activities of anti-tumor than 700 mycorrhizal samples, more than 300 population and anti-HIV-1. Concentricolide has significant blocking genetics materials and chemical constituents samples of effect on HIV-1 and host cell fusion as well as significant 30 species. On this basis, they carried out classification inhibition effect on cytopathy caused by HIV-1. This result and systematics research for some important groups in received U.S. patents. Meanwhile, they completed the total alpine and sub-alpine regions such as Albatrellus , Tuber and Lactarius and officially published 13 new species and 36 new combinations; researched the species evolution

Daldinia concentrica

Albatrallus tibetanus synthesis of concentricolide and induce Daldinia concentrica of the important species such as Tricholoma matsutake, to cultivate a new component, which has important Chroogomphus spp., Flammulina spp. and Lepiota significance for searching for new bioactive ingredients. cristata and acquired some valuable results; studied This research resulted in the publication of 36 papers, of the ectomycorrhizal ecology of alpine meadow -like which 30 were SCI papers, 8 of them were in top JCR 15%; Kobresia (Kobresia filicina ), etc, totally 4 kinds of typical provided one consultation report; applied for 5 domestic herbs, found that at least more than 150 taxonomic unit patents, obtained 2 authorizations; applied one US patent (OTUs) can form ectomycorrhizal relationship with them, and achieved authorization; found 2 key compounds worth as well, discovered for the first time that the carrot- depth study; cultivated 14 doctors and accepted 5 post- shaped roots have ectomycorrhiza fixation; successfully doctorals and visiting scholars from home and abroad. completed the mycorrhiza artificial synthesis of plant and India truffle fungi and obtain one patent license; completed the chemical constituents research of 20 fungi, purified more than 100 compounds, found 40 natural products with

R. qiaojiaense Tricholoma matsutake Tuber indicum

12 Research Progress on Natural Tobacco Mosaic Virus (TMV) Inhibitors

Voluminous research facts indicate that most secondary than that with other active medicals simultaneously. metabolites (Natural Products) of plants are of biological Benzylphenethylamine Alkaloids isolated from significance, the most representative function of which is plantaginea Aschers boasted salient anti-TMV effect, and its ecological effect or chemical defense. Since 2002, Hao Xiao- representative compound is IC50=1.8 μM of DDN (Journal of Jiang’s research group has been cooperating with Fang Natural Products , 2007(70), 1458-1461). Rong-Xiang’s research group of Institute of Microbiology, β-Carboline Compounds isolated from Picrasma and Zhang Zhong-Kai’s research group of Yunnan Faculty quassioides (D. Don) Benn boasted anti-TMV activity. It is of Agricultural Sciences of Biotechnology Research Institute worth noting that anti-TMV effect can be intensified when for study of natural tobacco mosaic virus (TMV) inhibitors β-Carboline Compound is combined with Nigakilactone from plants. The results of this collaborative research B which is lack of anti-TMV activity but isolated from the demonstrate that three different type of anti-TMV agents same plant. It is the first report on anti-TMV of β-Carboline were discovered from Strobilanthes cusia (Nees) Ktze and its synergistic effect against TMV when combined with and paniculatum (Bge.) Kitag., which showed quassinoid. It indicates that chemical combinations with different action mechanisms. Among them, Seco-pregnane different methods will probably have chemical defense of sterides are effective and selective inhibitors targeting to plants(Journal of Agricultural and Food Chemistry , 2009 subgenomic RNA of alpha-like positive-strand RNA virus (57), 6590- 6595). (Togaviridae ) including plant-infecting TMV, and It is discovered that the MeOH extract of the of animal-infecting Sindbis virus (SINV), eastern equine Brucia javanica (L.) Merr. ( Ya Danzi) boasted encephalitis virus and Getah virus,(PNAS ，2007(104)， salient anti-TMV activity. By screening-aimed isolation, 17 8083-8088). New chemical activator AHO induced the quassinoids and Glycoside have been isolated. The study systemic acquired resistance in plants via the salicylic acid- results showed that these quassinoids boast anti-TMV mediated signal transduction pathway (Plant Biotechnology activity on different degrees. Eight of them are superior to Journal , 2008(6), 301-308). Cinchonaglycoside C can induce positive control Lingnanmycin. The strongest one can reach a ribosome-inactivating protein (RIP), which boasts anti- 34 times greater than Lingnanmycin. Further study shows TMV function (Journal of Integrative Plant Biology , 2007 this compound not only inhibits viral infection but also (49), 1327- 1334). An anti-TMV activity test was conducted prevent the replication of virus. The study also makes an on the chemical activator AHO subsidized by important analysis of structure-activity relationship of anti-TMV activity tasks of Chinese Academy of Sciences in the field during of quassinois (Journal of Agricultural and Food Chemistry , 2010. After tobacco's inoculation treatment, the morbidity 2010 (58), 1572- 1577). of tobacco for following three weeks is 4.22%, 33.13% and 35.60% respectively. The tobacco treated with AHO is better

AHO Field test situation The results of the aetivity of Quassin resistance to TMV

13 Predicting Global Change through Reconstruction Research of Paleoclimate Predicting global change is a scientific question as well as Xiaolongtan was 1197.6-1463.8mm, while the rainfall in a general concern of human society. To accurately predict modern times is 820mm (Kaiyuan). This result inosculates global change, we must master the climate changes in with that of Miocene climate simulations. Further analysis geologic history time and history period. The reconstruction also found that the late Miocene rainfall of dry season of paleclimate can not only provide important basic reached 20% of annual rainfall in Yunnan, while the rainfall information for predicting global change, but also provide of dry season in the contemporary era only reaches 5% of an opportunity to discuss the interrelationship between annual rainfall, which indicates that a monsoon climate has geological events and global change. Researcher ZHOU been established in late Miocene era but have not achieved Zhe-Kun and his team, according to the Miocene flora the current intensity. According to the simulation results found in Yunnan Xiaolongtan, utilized the international of monsoon intensity and Himalayan lifting height, they method of quantitative reconstruction of paleoclimate speculated that Himalayas already had uplift in the late and reconstructed late Miocene paleoclimate in Yunnan. Miocene era but had not reached the present height. This The results showed that in the climate (average annual result is published on Paleogeography , Palaeoclimatology, temperature, annual range, the warmest month average Palaeoecology , an important journal in paleontology field. temperature and the coldest month average temperature) was similar to now. The average annual temperature was slightly 1-2℃ higher than the modern temperature. But the total annual rainfall was significantly larger than modern, thereunto; the annual rainfall in late Miocene in Kaiyuan

Comparison of average annual temperature of Neogene and modern flora of Yunnan

Comparison of average annual rainfall of Neogene and modern flora of Yunnan Comparison of average annual rainfall of Miocene and modern 14 Chemical Composition of a traditional Chinese medicine-Swertia mileensis

Professor -Jun and his colleagues systemically studied the chemical components of traditional Chinese medicinal herbs-Swertia mileensis to provide 23 interesting new compounds and another 16 compounds. Based on spectral evidence and X-ray single diffraction analysis, these new compounds had be elucidated as 4 novel types of iridoid lactones composing of C18, C20 , C29 including A-G (swerilactones A-G), and one novel type of iridoid lactones to possess naphthalene including swerilactones H-I. In addition, there is one novel secoiridoid aglycone dimer maned swerilactones J, nine new seco-iridoid aglycones including sweriridoids A-I and four novel secoiridoid aglycones dimer linked by glycosidic bond -- sweriridoids J-M. The biosynthesis ways of these novel iridoid lactones have preliminarily studied, which the results were published in the Org.Lett ranked top 15% in journals of related fields. The anti-HBV activities on the Hep G 2.2.15 cell line in vitro of these compounds separated from Swertia mileensis were evaluated and results showed that swerilactone H exhibited well anti-HBV activities against the secretion of HBsAg with SI of 9.84 and HBeAg SI of 4.16, respectively. Moreover, the other two compounds showed moderate anti-HBV activity. The series of iridoid lactones with novel skeletons isolated from Swertia mileensis not only greatly enriched the compound bank of natural products but also provided an important chemical and physical basis for the rational use of Swertia mileensis of the Yunnan's unique TCM. This work was granted by the key projects of NSFC-Yunnan Joint Fund Swertia mileensis (U0832603).

Part of the structure of novel compounds

15 Mountain Ecosystem Research has Made New Progress

The - Plateau lies in the heart of Asia and especially resulting in the reduction of water table and a steady stream of its glacier melt injects into the top ten dry season runoff. The study proposed to inspirit the local rivers in Asia. The effects of climate change exceed the residents to protect the existing forest resources through global average. Research found that the higher the more ecological compensation measures and change the situation obvious the temperature elevation is. A paper by researcher of monoculture rubber plantations by Agroforestry. XU Jian-Chu, published in Conservation Biology , fully revealed the far-reaching implications of climate warming on water resources, biological diversity, ecotone and the agro-ecological environment as well as providing feedback on global environmental change. The research suggested establishing local and regional scale joint research so as to reduce the uncertainty of assessment impacted by climate change and setting up climate change mitigation and adaptation measures and early warning mechanisms and changing passive adaptation to active adaptation. At the same time, rubber cultivation is expanding at an alarming rate from southern Yunnan to Southeast Asia Mountains. More than 50 million hectares of mountains have been converted to rubber plantations in China, Laos, , , Cambodia and Myanmar. What will the environmental impact be if large areas of forests turn to rubber plantation? The study co-published on Science by Elevation map of China researcher XU Jian-Chu and National University of Singapore indicated that the large-scale monoculture of rubber not only directly threaten biological diversity, causing a reduction of total biomass and carbon sequestration, but also have a negative impact on he hydrological process,

Rubber Plantation in southern Yunnan

16 Plant Cyclic Peptide has Made Important Progress

After the publication of the Study of Plant Cyclic Peptide of using radix pseudostell cyclic peptide B as the medicine which produced an important summary in Chemical Reviews quality control of herb radix pseudostell was used by 2010 (2006，106：840), which received the first prize of Yunnan version of "Chinese Pharmacopoeia". In the active cyclic Natural Science (2006), researcher TAN Ning-Hua was peptide discovery and mechanism research, they screened awarded funding from the National Fund for Outstanding the activities of more than 40 cyclic peptides, including more Young Scholars to expand the study direction from finding than 30 models of anti-tumor, anti-virus, anti-bacterial, plant cyclic peptide to researching the structure and function immune, diabetes and hemolytic, finding that most screened of plant cyclic peptide. After nearly two years’ effort, cyclic peptide are with anti-tumor activity and discovered they achieved many outstanding results. In the following two sign molecular, that is, anti-tumor activity RA-V and study, 5 types of structure and compositions of 17 plant the new anti-HSV-1 RA-V and new immune activity AS1; cyclic peptides of Violaceae, Cucurbitaceae, Rhamnaceae, completed the analysis of 2 kinds of active cyclic peptide Caryophyllaceae, Euphorbiaceae, , Compositae, structure-activity; constructed 3D databases of 500 cyclic and Lamiaceae in the aspect of Plant Cyclic peptides; developed the study of conformation theory and Peptide discovery, obtained 80 Cyclic Peptide, including 2 cyclic peptide biosynthesis exploration of 3 cyclic peptides new frameworks, 30 new cyclic peptides; founded a new as well as their analogues. method of TLC rapid detection for Violaceae-type cyclic peptide (Ring protein) (that is, improve the methods of thin-layer coloration for the ring protein by Coomassie blue light G-250, (Chinese Science Bulletin，2008,，53： 1671)), chromatographic separation and structural research methods (collected in the new edition “Chinese Herbs Extraction Method”); separated 40 ring protein from 5 kinds of plants, half of which are new protein, obtained the first crystal structure of ring protein cooperated with Professor David Craik, University of Queensland, Australia (Journal of Biological Chemistry ，2009，284：10672); the methods

New frameworks cyclie peptides

Crystal structure of ring protein

17 Progresses in Computational Chemistry Research

At present, natural product chemistry study is confronted related patent and published a PCT patent. Through years of with a predicament, namely, the stereochemistry research. efforts, the research team has published high-level research The three-dimensional structure of some compounds cannot papers on Chem. Eur. J.; J. Org. Chem . and Org. Lett ., etc. be effectively identified due to the small quantity obtained The published book, "Modern Organic Stereochemistry" in experiments, complexity of structure or other reasons. (Science Press in Chinese) has selected as one of a series of At the same time, it is found that the biogenetic route textbooks for graduate students use in creative education. for new compounds, which also became a hot concern of organic synthesis and theoretical chemists, is quite difficult to solve. Both of these related to theoretical chemistry. Through years of research, Professor ZHU Hua-Jie, with his team, formed their own unique research style in an interdisciplinary area and made remarkable achievements. Combined with the development of supercomputers, they carried out in-depth discussion about these two separate but interrelated research activities. In the research of three-dimensional structure of complex natural products, they constructed novel calculation methods on the basis of quantum chemistry calculation. For example, they established a biogenetic way for some natural products through calculating the conversion energetics (transition state barriers) among different products. As well, they have synthesized bioactive molecules, including the compounds that can protect central nerve cells, and thus secured

The structure for mdecular sirnulation in the calculation process

The compound structure for mdecular Chemistry calulations of simulated identification of the absolute configuration transition state of the chernical reaction

18 New Progress in the Total Synthesis of Natural Products

Conquering complex natural products by total synthesis has always been a symbol of the advancement of organic chemistry. Total synthesis of challenging and complex natural products is also recognized as one of the toughest fields in the physical science. At present, Chinese chemists still lag far behind many of the competitors from developed countries in total synthesis of natural products. There also had, to date, been no systematic studies of the total synthesis in KIB. As of July 2008, Prof. Yang Yu-Rong’s laboratory is aiming at total synthesis of some structurally complex and biologically active natural product in KIB. After one year of great effort, this laboratory has made progress in the total synthesis of the Lycopodium alkaloids through development of a general synthetic strategy, three alkaloids including (-)-8-deoxyserratinine, (+)-lycoflexine and (+)-fawcettimine synthesized successfully; two of which were achieved for the first time. Additionally, Yang and co- workers first reported their synthetic studies on lycojapodine in a top journal J.Org.Chem.

19 New Progress on the Ecological Function Research of Plant Secondary Metabolites

More and more research showed that plant secondary Leucosceptrum canum , a large woody and colored metabolites have a variety of ecological functions such plant of Labiatae family, and their ecological significance, as defense, attraction, signaling and UV protection. which will help to reveal the evolutional relationship Researchers -Hong and his colleagues, under between the secondary metabolites of this plant and its the support of starting funding for talent introduction of special traits-“large woody” and “colored nectar”. KIB, the independent projects of State Key Laboratory and National Natural Science Foundation, established the Chemical Ecology Research Group and carried out studies on the ecological functions of plant secondary metabolites. The Group has studied the secondary metabolites of the invasive plant Eupatorium adenophorum and their ecological functions, and found that only a small number of its major components (cadinene sesquiterpenes) showed weak allelopathic effect to the seed germination of thaliana , but most terpenoids have no significant effect, which is not consistent with previous reports at home and abroad. This indicated that terpenoids are not the major allelopathic substances of this plant while non- terpenoids (such as phenolics) might be. The above results have been published on Journal of Agricultural and Food Chemistry (2009, 57: 478-482). Further investigation on the allelochemicals and the defensive function of terpenoids of this invasive plant is currently underway. Meanwhile, the Group is also investigating the secondary metabolites of

A: L. canum plant in bloom; B-C: Trichomes on the surfaces of L. canum; D: Nonglandular trichomes; E: Peltate glandular trichomes; F: Capitate glandular trichomes.

Eupatorium adenophorum

Leucosceptrum canum

Novel defensive sesterterpenoids from glandular trichomes of L. canum and the X-ray crystallographic structure.

20 The Chemical Research of Ferns Obtained New Progress

Researcher Qin-Shi and his team, focused on the Southwest China for a long time, carried out chemical research of fern and found new activity components. Then, on this basis, they studied structural modification, structure-activity relationship and drug design, and then developed innovative drug research. They investigated fern resources in Yunnan and focused on the research of chemical composition of lycopodiaceae, Huperziaceae and Gleicheniaceae plants; successfully applied for the National Natural Science Foundation- the project of United Fund of Yunnan Province “the find of lead compounds and the mechanism research of the endemic fern in Southwest regions” (U09326602, 1.80 million); studied Lycopodiaceae plant (Lycopodium japonicum Thunb.), separated more than 50 compounds, found a new alkaloids Lycojapodine A and the result was issued on Org. Lett ., 2009,11(6), 1397-1400. And Dr. YANG Yu-Rong studied its total synthesis.

The chemical structure of Lycojapodine A

Lycopodium japonacum Thunb.

21 Successfully Propagating and ex situ Conserving the Critically Endangered Plants

Yangbi Acer yangbiense, a tree species described 50 three-year-old M. coriacea of known source have been in 2003, is known from only four individuals scattered in reintroduced to its natural habitat by Yanjiaguo Village, the secondary woods on the western slopes of the Canshan , southeast Yunnan province of China. The Mountain range in Dali, in the west of Yunnan Province, scientific aftercare, monitoring and data collecting for those China. Kunming Botanical Garden (KBG) under Kunming reintroduced saplings have been carried out to date. Institute of Botany, obtained some 3000 hand pollinated seeds from Dr. Chen You-Sheng (Institute of Botany in ) in October 2008. Researchers from KBG conducted 4 months of experimentation of seed germination adopting various treatments; seeds successfully germinated and were sown. By February 2009 c, 1500 seedlings had successfully germinated. These seedlings provide hope that Yangbi maple may be saved from extinction by means of ex situ conservation at KBG and plant reintroduction or reinforcement to its natural habitats. Presently, Professor SUN Wei-Bang’s team carried out comprehensive studies on cytogenetics, physiological ecology and genetic variation between and among the existing wild individuals and the The gernination of treated Yangbi maple seeds propagated seedlings. The aim is to use the information from these studies to restore the species population in the wild. Globally, Michelia coriacea and phanerophlebia are the critically endangered trees from family Magnoliaceae. These two species are narrowly endemic to southeast Yunnan Province, China, and the limited extant individuals were scattered in the evergreen limestone forests. Professor SUN Wei-Bang’s team has comprehensively studied the reproductive biology of M. coriacea , meanwhile, the preliminarily studies on the population ecology and pollination biology of M. phanerophlebia have also been conducted. Based on the understandings of seed biology of the two species, around 990 seedlings of M. coriacea and 128 M. phanerophlebia seedlings have been obtained from the hand pollinated seeds. In mid-June 2009, a total of Artifical breeding of Yangbi maple seedlings

Michelia coriacea Chang et B. L. Chen

22 The Research of Planting “Golden Oriole” Promoted the Development of Yunnan Flower Industry

Since 1997 when the “golden oriole” was introduced base, their atpB-rbcL and trnL-F sequence in chloroplast in Yunnan for floriculture, its ornamental value has been are quite different, 5 and 15 base differences respectively. recognized and has enjoyed large-scale cultivation and In the same condition, the germination rate of “golden brought economic benefits. Its products are sold in oriole” is only 2%, while that of Canadian Solidago is as many other . However, because its high as 95%. The research preliminarily confirmed that the morphology is very similar to that of the Canadian Solidago , cultivation of “golden oriole” in Yunnan is safe and under the cultivation of which is boycotted. For many years, control. However, as the "golden oriole" has a certain ability researcher GONG Xun and his team carried out comparative to reproduce, there are potential possibilities of escaping studies of the “golden oriole” planted in Yunnan and to the wild and causing ecological disaster. We hope that Canadian Solidago , and found that although the shape of relevant departments strengthen monitoring of the plant. “golden oriole” is similar to Canadian Solidago , “golden The results provided scientific evidence for the cultivation oriole” was diploid 2n=2x=18 , while the Canadian （ ） and sale of “golden oriole” in Yunnan and communicated Solidago spread throughout eastern China was hexaploid on the “golden oriole” seminar organized by Ministry of 2n=6x=54 . Polyploidy generally is more adaptive and （ ） . invasive than diploid. In DNA, although the ITS sequence of "golden oriole" and Canadian Solidago differs in only two

Canadian Solidago "Golden oriole"

23 4. ACHIEVEMENTS AND AWARDS

"Compilation of Flora Reipublicae Popularis Sinicae " won the first prize of 2009 China's State Natural Science Award

"Compilation of Flora Reipublicae Popularis Sinicae ", as member of the standing committee. LI participated in completed by famous botanists including QIAN Chong-Shu, editing 65th (2) fascicule, 66th volume (Labiatae) and took CHEN Huan-Yong, WU Zheng-Yi, WANG Wen-Cai, LI Xi- charge of compiling 31st volume () and 50th (2) Wen, HU Qi-Ming, -Lin, CHEN Xin-Qi, CUI Hong-Bin fascicule (Clusiaceae), involving 4 families 62 genera 541 and -Da, won the first prize of 2009 China's species. The main academic achievements of LI Xi-Wen State Natural Science Award. The first prize of China's State include gaining a clear idea of all the species of Labiatae, Natural Science Award was once vacant for 7 years and was Lauraceae and Clusiaceae; giving detailed explanation vacant again in 2007 and 2008. Academician WU Zheng- of name, morphological specificity, phenological period, Yi and Researcher LI Xi-Wen from Kunming Institute of habitat, distribution, utilization and systematic position of Botany, CAS, are respectively ranked 3rd and 5th among all each species; providing excellent pictures together with the prize-winners. the explanations; and publishing academic articles and Academician WU Zheng-Yi held the post of member of papers on newly categorized species, phylogeny and plant Editorial Committee of Flora Reipublicae Popularis Sinicae geography. These achievements lay a steadfast foundation from 1959-1972, associate editor from 1973-1986 and chief for development and utilization of plant resources, editor form 1987-2004. While WU was the chief editor, 54 phylogeny and floristic study and biodiversity conservation. volumes 82 fascicules of Flora Reipublicae Popularis Sinicae In addition to Academician WU and Researcher were finished and published. In the period of chief editor LI, scholars and scientists from Kunming Institute of and associate editor, WU spent a lot of time looking over Botany, who are members of Editorial Committee of Flora the volumes and fascicules in accordance with herbarium Reipublicae Popularis Sinicae , are CHEN Jie (compiling 65th specimens. In addition, he took on some difficult and major volume 1st fascicule, 58th volume, involving 5 families tasks and accomplished 2/3 of the whole compilation. WU 40 genera 393 species); and CHEN Shu-Kun (compiling was responsible for and pro-active in editing the following 43rd volume 3rd fascicule, 45th volume, 73rd volume 1st 9 volumes which contained 8 families 152 genera 1109 fascicule, involving 4 families 16 genera 292 species); species (according to incomplete statistics), including Other KIB staff include FANG Rui-Zheng (compiling 57th 65th (2) fascicule, 66th volume (Labiatae); 67th (1) volume 1st fascicule, 57th volume 3rd fascicule, involving 4 fascicule (); 64th volume (Convolvulaceae, families 29 genera 304 species); FENG Guo-Mei (compiling Polemoniaceae, Hydrophyllaceae); 13th volume (Araceae, 49th volume 2 fascicule, involving 1 family 16 genera 83 Lemnaceae); 26th volume (Caryophyllaceae); 23rd volume species); MIN Tian-Lu (compiling 45th volume 1st fascicule, (Moraceae); 32nd volume (, Capparaceae); involving 6 families 21 genera 73 species); CHEN San-Yang 1st volume (General Instruction); etc. (compiling 13th volume 1st fascicule, involving 1 family 26 Researcher LI Xi-Wen took the position of member of genera 99 species); PEI Sheng-Ji (compiling 13th volume Editorial Committee of Flora Reipublicae Popularis Sinicae 1st fascicule, involving 1 family 26 genera 99 species); and from 1973-2004, lasting 26 years among which 17 years WU Su-Gong (compiling 13 volume 1st fascicule, involving

24 2 families 3 genera 159 species). Botanists who also Zheng-Yi successively took the position of chief editor. participate in compilation of the Flora Reipublicae Popularis Academician WU Zheng-Yi acted as chief editor for 17 Sinicae are ZHUANG Xuan (editing 4 families 45 genera 269 years and accomplished 2/3 of the whole compilation work, species), SU Zhi-Yun (editing 1 family 1 288 species), making significant contribution to the completion of Flora LI Heng (editing 4 families 47 genera 232 species), Reipublicae Popularis Sinicae . In September of 1959, the Shu-Qiong (editing 3 families 8 genera 133 species), HUANG first fascicule (Pteridophyta), edited by Academician QIN Su-Hua (editing 3 families 26 genera 132 species), BAI Ren-Chang, was published. After that, four generations Pei-Yu (editing 1 family 13 genera 106 species), XU Ting- of 312 scientists from domestic scientific institutes Zhi (editing 2 families 12 genera 79 species), XUAN Shu- and universities and 176 botanical illustrators joined in Jie (editing 1 family 12 genera 57 species), TAO De-Ding compilation of Flora Reipublicae Popularis Sinicae . (editing 3 families 21 genera 48 species), YIN Wen-Qing Under the consistent support of CAS, NSFC and MOST, (editing 1 family 18 genera 45 species), LI -Hui (editing after 45 years endeavor, the Flora Reipublicae Popularis 3 families 9 genera 44 species), BAO Shi-Ying (editing 2 Sinicae was published in 2004 with 80 volumes 126 families 5 genera 43 species), CHEN Zong-Lian (editing 1 fascicules, amounting to 50 million Chinese characters. To family 1 genus 31 species), TONG Shao-Quan (editing 3 date, the Flora Reipublicae Popularis Sinicae is the largest families 11 genera 31 species), LI De-Zhu (editing 1 family flora reference in the world. 1 genus 29 species and member of the Editorial Commitiee Compilation of Flora Reipublicae Popularis Sinicae is for 1997-2004), ZHOU Xuan (editing 1 family 6 genera 24 a tremendous system project. During the entire project, species), LI Ya-Ru (editing 1 family 2 genera 15 species), researchers collected more than 17 million plant specimens TAO Guo-Da (editing 1 family 5 genera 14 species), CAI Xi- outdoors, studied and referred to almost 17 million Tao (editing 1 family 4 genera 9 species), CHEN Pei-Shan herbarium specimens, took over 20 thousand photos of (editing 1 family 1 genus 1 species), etc. PENG Hua, LI rare plant specimens (especially type specimens), drew De-Zhu, SUN Hang and ZHOU Zhe-Kun, 4 researchers of up hundreds and thousands of reference cards, proposed Kunming Institute of Botany, contribute to compilation of new genera and genera names with a total number of 243, 1st volume of the Flora Reipublicae Popularis Sinicae . and presented 14312 new species and species names. Four Flora Reipublicae Popularis Sinicae is a monumental generations of botanists bravely forged ahead with whole work which summarizes the classification of vascular plants heart. They journeyed all over the country to inspect plants in China. The book contains 80 volumes 126 fascicules, and collect specimens. Their persistence and preciseness amounting to over 50 million Chinese characters. In the show the high spirit of Chinese botanists. Flora Reipublicae Popularis Sinicae , 301 families, 3408 Flora Reipublicae Popularis Sinicae is not only a "register genera, 31142 species of vascular plants are recorded with book" of each plant, but also important database for nearly 9000 pictures. recording and studying botanic features of plants. It is In 1956, Flora Reipublicae Popularis Sinicae was officially regarded as the most foundational scientific work and the put into the Program for the Development of Science most important information carrier in botanical research and Technology proposed by CAS. In 1959, the Editorial and study. Flora Reipublicae Popularis Sinicae , as the most Committee of Flora Reipublicae Popularis Sinicae was accurate, most comprehensive and most canonical academic established by CAS with Academicians QIAN Chong-Shu and work on recognition and record of plants in China and CHEN Huan-Yong as chief editors. Afterwards, Academician peripheral countries and regions, lays a profound foundation LIN Rong, Academician YU De-Jun and Academician WU for sustainable development of plant resource and provides indispensable reference for deep study on agriculture and forestry development, ecological transition and global warming issue.

25 KIB Wins the Title of "Outstanding Unit" in 10th Anniversary of Sci-tech & Industrial Base for Traditional Chinese Medicine (TCM) Modernization, and Academician ZHOU Jun et al Awarded as "Advanced Individuals"

Since Sci-tech & Industrial Project for Traditional Chinese constituents in anti-HBV medicine, study on anti-virus Medicine (TCM) Modernization was put into action, it has active constituents in Strobilanthus, study on botanical gained lots of attentions from leading cadres of all levels. chemistry and pharmacological activity of non-medicinal This project mainly centers on protection and sustainable dendrobium, study on cyclopeptides in plants, study on utilization of plant resources in order to orient towards pharmacologically active compounds in higher fungi; the international trend of science and technology and the study on chemical features of Pteridophyta, and study on state strategic demands, and serve the regional economy research, development and mechanism of action of alstonia and local economic construction. It also undertakes two leaf and other 4 new medicines' function in relieving cough platform constructions including "Large-scale Equipment and asthma. These achievements are significant in the Sci- Public Laboratory of Yunnan Province" and "Natural Medicine tech & Industrial Base for Traditional Chinese Medicine (TCM) Screening Laboratory"; introduces 6 talents and elitist at Modernization and the sci-tech development of TCM. On the home and abroad, who are engaged in study of herbal recommendation of Science and Technology Department of medicine; successfully transfers "SH", a compound herbal Yunnan Province, Kunming Institute of Botany (KIB) was medicine for AIDS, and "EMEI Capsule", a medicine for conferred the title of "Outstanding Unit" in 10th Anniversary gynecological disease, to Yunnan Province; and actively of Sci-tech & Industrial Base for Traditional Chinese Medicine provides Yunnan Province and the west area with technical (TCM) Modernization in November 9th, 2009, together with service, and medicinal company and research institute another 91 units. At the same time, Academician ZHOU Jun, with analysis and test, drawing up over 20 thousand Academician SUN Han-Dong and Researcher YANG Chong- high quality spectrograms. Moreover, a lot of progress Ren were awarded as "Advanced Individuals". has been made during the process of TCM modernization project, including study on chemical constituents of , study on anticancer compound in Rabdosia, study on for injection, study on active

Professor LIU Ji-Kai Wins 2nd TAN Jia-Zhen Bioscience Innovation Award

In 2nd TAN Jia-Zhen Bioscience Award, Researcher LIU are published on Chem Rev, Org Lett, Cur Med Chem , J Ji-Kai was honored with TAN Jia-Zhen Bioscience Innovation Nat Prod, J Antibiot , and Phytochemistry are included by Award. There are 2 winners of TAN Jia-Zhen Bioscience SCI, amounting to almost 120 articles and 1 monograph. Achievement Award and 9 winners of TAN Jia-Zhen Besides, he has also applied 10 patents (thereinto 2 Bioscience Innovation Award. international patents) and 7 of these have been authorized. With rich higher fungi resources in Southwest China, In 2003, LIU was honored with the second prize of National LIU Ji-Kai systematically conducts his research on chemical Nature Science Award as the second winner. After that, constituents and bioactivity with modern technology, and because of his excellent research, he won Yunnan Province gradually forms his own characteristics. LIU has deeply Nature Science Award as the first winner in 2007. studied the chemical constituents and bioactivity of over Researcher LIU Ji-Kai’s work is systematical, innovative 100 kinds of higher fungi, isolated and identified nearly and full of outstanding characteristics. Now, his research 500 different compounds, and discoved 150 new chemical center is one of the worldwide research centers for studying constituents in higher fungi, including 5 new structures and higher fungi's chemical constituents and bioactivity. His a series of bioactive substance which are specially structured great achievements significantly contribute to the field of and worth deep study. 5 of those new-found compounds chemical constituents and bioactivity of higher fungi. are successively listed as "Hotspot" by Nat Prod Rep , an international authoritative magazine of natural products. Liu's research focuses on new chemical constituents and bioactivity in high fungi and the development of new medicine. The research has made remarkable progress. To date, LIU, as first author or corresponding author, has published more than 220 academic articles on national and overseas academic journals. Some of his articles which

26 Study of Alpine Plant Diversity

Type and Class of Award: First Prize of Yunnan Province Science & Technology Award, Nature Science Division. Completion Unit: Kunming Institute of Botany, CAS; Yunnan Normal University Main Contributors: SUN Hang, NIE Ze-Long, ZHOU Zhe-Kun, LE Ji-Pei, GU Zhi-Jian, LI Zhi- Min, Tu Tie-Yao, ZHANG Yong-Hong, CHENn Shao-Tian, ZHANG Da-Cai, , ZHANG Jian-Wen, ZHA Hong-Guang

Main Contents and Impacts: Diversity Study of Alpine Plant, under the support of of flora in this area. Completely evolved phyla are often National Natural Science Foundation of China (General locally formed. Regarding to migratory route, the migration Program) and Natural Science Foundation of Yunnan by Laurasia and Bering Land Bridge has main effect on the Province, has made an abundance of scientific achievements flora formation of this area. throughout 8 years of research. The project systematically From the research on cytogeography and ploidy evolution discusses the origin and evolutionism of diversity of alpine of some important phyla grown in extreme environments plants in Hengduan Mountain and Tibet Plateau from macro of the Henghuan Mountain and Tibet Plateau, researchers angle and molecule angle. It sets a necessary stage for come up with the findings that polyploidy frequency takes deep comprehension of the origin and evolutionism of alpine no advantages in flora formation which mainly bases on flora and indeed, the flora of north temperature zone, and diploid level. serves a basis for protection and sustainable utilization of There are, in total, 49 academic articles published, 33 biodiversity. Research findings generally play a leading role articles collected in SCI. Besides, the project has cultivated in domestic research field and some of the findings reach 10 candidates. the international advanced level. Diversity Study of Alpine Plant is organized and led by SUN Hang, a researcher in KIB. In collecting basis materials, researchers conduct several surveys on alpine in northwest Yunnan, west Sichuan, Tibet, Sinkiang, Qinghai and , gathering nearly 6000 species, 24000 samples. To date, 1 new genus and 8 new species have been discovered, thus filling a blank in research and collection of species-specific floras or floras in frail eco- environment, and providing new data or information for botanical research and biodiversity protection. As for the research on the origin and evolution of alpine flora in Hengduan Mountain, the project, integrating paleobotany, geology, history, plant systematics and geographical analysis of flora, and combining the research with latest molecular systematics, reveals that Tethys flora is a crucial origin of the modern flora in Hengduan Mountain. The research on the origin of endemic genera and the origin and differentiation of endemic genera of Chinese flora shows the origin of Chinese endemic genera is of two stages, i.e. ancient endemism happened in Cretaceous and Paleogene, which is now residually distributed; neo endemism happened in Neogene, which is locally derived from Tethys, the Arctic Pole, Tertiary and Neogene. It can also be found from the research on molecular systematics and biogeography of Tibetan endemic phyla and phyla between East Asia and North America, such as Solms-Laubachia, Incarvillea, Pseudechinolaena, Phryma, , and etc., that differentiation by distance and differentiation by migration are main forming mechanism

27 A Study on Novel-structured Alkaloids from Daphniphyllum

Type and Class of Award: First Prize of Yunnan Province Science & Technology Award, Nature Science Division. Completion Unit: Kunming Institute of Botany, CAS Main Contributors: HAO Xiao-Jiang, Ying-Tong, HE Hong-Ping, LI Chun-Shun, MU Shu- Zhen, , , KONG Ning-Chuan, ZHANG Qiang, TAN Cheng-Jian, LI Shun-Lin

Main Contents and Impacts: "Hot Chemical Compound" by Natural Products Report, an After years of research, the project has updated and international authoritative magazine of natural products. improved system approach in extraction, isolation, structure It is an uncommon phenomenon that two alkaloids analysis and chemical calculation. Taking small amounts of different biogenetic ways are discovered in one plant. of alkaloids from Daphinphyllum as research material, the However, the project firstly discovers, in Daphniphyllum project has made significant results. Longeracemosum and Daphniphyllum, C-19 and C-20 Alkaloids from Daphniphyllum are of unique, polytropic diterpenoid alkaloids and matrine which are of special and complicated polycyclic-structure matrices. Its special biogenetic ways different from alkaloids in Daphniphyllum. approach of biogenetic synthesis and biomimetic synthesis This causes new exploration and thinking of biogenetic ways was once a hot but challengeable topic for chemists of of secondary metabolites. natural products and chemists of organic synthesis. This During the preliminary bioactivity screening of alkaloids project conducts research on constituents and activity of in Daphniphyllum, the researchers first find out that some alkaloids from 7 species of Daphinphyllum (accounting alkaloids perform good bioactivity in platelet aggregation for 70% of indigenous species and 100% of the species inhibition and antioxidation. This new finding expands the grown in Yunnan Province) from the aspects of different alkaloid diversity. Discovery of nicotinergic receptor and collection locations and different parts of the plants where cholinergic receptor provides important information for the alkaloids is extracted, and has generally solved those ascertaining whether these alkaloids have ecological effects. tough problems such as low contents of alkaloids from There are totally 26 academic articles published in which Daphinphyllum, technically demanding isolation, complicated 24 articles are collected in SCI, accounting for 60.5 Impact structure analysis, etc. It vastly enriches matrices of the Factors. 21 articles are cited by SCI-E and CPCI-S for 225 alkaloids from Daphinphyllum. Furthermore, new biogenetic times in which 78 times are other-cited. The highest other- ways and its biological importance are adequately and cited rate of a single article is 19 times. In addition, 7 conducively discussed. compounds are listed as hot chemical compounds by Natural A research on alkaloids constituents in 7 species of Products Report. Daphinphyllum is conducted from the aspect of different The project has cultivated 7 doctorial candidates, 5 collection locations and different parts of the plants where of who have obtained the Ph.D. degree; and 2 master the alkaloids are extracted. As a result, 170 alkaloids are candidates. 2 doctors get the CAS Chancellor Outstanding isolated and identified, including 26 kinds of matrices. Among Award and the correlated funding, and 1 doctor is awarded these findings, there are 17 new kinds of matrices and 80 as CAS Outstanding Graduate. novel-structured alkaloids. Since the nationally first alkaloid To sum up, the project carries on a profound and from Daphinphyllum was discovered and published in 1993, systematic study on alkaloids in Daphniphyllum. Its scope the project has put forward 12 new-matrix alkaloids and 56 and depth can be regarded as top in the academic field. novel-structured alkaloids, thus making the project team It also provides new ideas for future study on biomimetic itself a fruitful research team at home and abroad. synthesis and biological importance. The project, in all, proposes 13 hypotheses on biogenetic ways of new alkaloids and amends those wrong structures and biogenetic ways in previous studies. The profound understanding of biogenetic ways lays a steady foundation for future study on diversity and novelty of secondary metabolites. By deep study on biogenetic ways and transition states, the project also provides an important basis for proving whether the plants contain Diels-Alderase, Mannichoid bio-enzyme or Pinacoloid bio-enzyme. A new natural Oxa-cage micro molecule is discovered. Accordingly, a chiral synthesis of its optical antimer and a bioactivity test are conducted. Once the academic article was published, the newly-discovered molecule was listed as 28 Investigation, Research & Protection of Spermatophyte Diversity in Southeast Yunnan & Adjacent Areas

Type and Class of Award: Second Prize of Yunnan Province Science & Technology Award, Nature Science Division. Completion Unit: Kunming Institute of Botany, CAS, Yunnan University, Yunnan Forestry Academy Main Contributors: SHUI Yu-Min, CHEN Wen-Hong, HUANG Su-Hua, SIMA Yong-kang, CHEN Shao-Yu, ZHANG Mei-De

Main Contents and Impacts: The project takes Southeast Yunnan, one of the areas Southeast Yunnan as well as providing powerful technical with the richest Spermatophyte species in Yunnan Province support to the local environmental protection. First of all, or even in China, as its research area. On the basis of the project team organizes or takes part in integrated previous study and the features of tropical mountainous flora survey in 4 national nature reserves and 4 provincial region and Karst landform, the project chooses vacant nature reserves, and provides multiple services for railways seasons (rain season & winter), frail region (Karst region, and national defense highways within the nature reserves, Xilong Mountain, etc.), endangered phyla (Begonia, including environment assessment, technical evaluation of Elatostema, etc.) and unique ecosystem (adnascent trimming and deforestation, labeling the plants of ecotouris vascular phytocoenosis, limestone palm phytocoenosis, etc. Second, on account of the fact that Southeast Yunnan etc.) and conducts a major investigation, collecting nearly has lots of protective plants in concentrated distribution, 30 thousand specimens. The investigation shows that, up the project team conducts a study on conservation biology to now, 63 type specimens of newly-identified phyla, 3 on national conservative plants including Cycas tanqingii, voucher specimens of Chinese newly-recorded genera, 2 , Yunnan Parakmeria spp., Cephalotaxus voucher specimens of Yunnan newly-recorded genera, 24 oliveri, etc., and accordingly provides theoretical guidance Chinese newly-recorded species and lots of Yunnan newly- for effective protection of species-specific plants in recorded phyla have been discovered. This partly enriches Southeast Yunnan. Moreover, through the ethnobotanical Spermatophyte species composition in Yunnan Province study on non-timber forest products which are traditionally and in China. Based on the investigation, the project collected and used by Ethnic Yao Chinese in Dawei Mountain carries out a taxonomic study on typical tropical or Karsts region, the project team explores the way to coordinate the phyla including Begoniaceae, Magnoliaceae, , relationship between the management of nature reserves Balsaminaceae, Gesneriaceae, Celastraceae, , and the daily life of local people. Finally, the project team Melastomataceae, Rubiaceae, Acanthaceae, Vacciniaceae, has collected 1200 seed specimens which enrich the species Convolvulaceae, Thymelaeaceae, , Connaraceae, data base of Southwest China. , Capparaceae, Polygalaceae, Sladeniaceae, During the 20 years careful and comprehensive , Myrsinaceae, etc. The study helps find 69 investigation, especially the survey on sections of vulnerable newly-identified phyla which are subordinate to 20 genera ecology and special ecosystem, the project has collected 14 families. Some of these newly discovered species are 31 thousand specimens of plants, discovered and published not timely recorded in Flora of Yunnan or , but 63 newly-defined phyla, 3 Chinese newly-recorded genera will certainly be first-hand information in Spermatophyte and 2 Yunnan newly-recorded genera as well as 24 studies. After investigation and taxonomic study, Chinese newly-recorded species and lots of Yunnan newly- researchers draw up a directory of different sections in recorded phyla. The researchers mainly focus on taxonomic Southeast Yunnan and preliminarily analyze the flora in the study on Begoniaceae, Mangnoliaceae, Orchidaceae and area which contains Dawei Mountain, Huanglian Mountain, Balsaminaceae in Southeast Yunnan, and participate in Fenshuiling, Wen Mountain, Laojun Mountain and Honghe compilation of Flora of Yunnan and Flora of China. Area. According to the analysis, it can be initially judged On the basis of analysis of the flora in the area which that there are 255 families, 1697 genera, 7560 species contains Dawei Mountain, Huanglian Mountain, Fenshuiling, (excluding classification below species rank; if included, Wen Mountain, Laojun Mountain and Honghe Area, a the number is 8363) of Spermatophyte in Southeast directory of Spermatophyte flora can be made and it Yunnan, accounting for over 1/2 of Spermatophyte in can be judged that there are 255 families, 1697 genera, Yunnan Province and 1/4 of Spermatophyte in China, 7560 species (excluding classification below species) of some of which are even unknown species. The findings not Spermatophyte, showing rich biodiversity in Southeast only show biodiversity in Southeast Yunnan, but also lay Yunnan. a steady foundation for cooperative study and scientific The project also carries out a study on conservation communication between China and tropical Southeast biology of key species and species-specific plants, thus Asia, especially countries in Indo-China Peninsula, such as providing theoretical foundation for protection of species- Vietnam. In the meantime, the project team takes part in specific plants in Southeast Yunnan. establishing nature reserves, preserving endemic species in

29 There are totally 3 monographs edited and 54 academic basic information of biodiversity of the plants in this area articles published. 20 articles are collected in SCI and 30 and thereby lays a steadfast foundation for bio-resources articles are cited by SCI-E and CPCI-S for 124 times in protection and sustainable utilization. The findings, with which 74 times are other-cited. 40 articles are cited by complete and reliable information and data, reach the CSCD and CNKI for 129 times in which 116 times are other- advanced level in domestic field, and part of them reaches cited. international level. In conclusion, the project discovers and publishes a large number of new-identified phyla, investigates the

A Study on Plant Origin, Material Basis, Quality Evaluation System & Secondary Fermentation Technique of Puerh Tea Type and Class of Award: Second Prize of Yunnan Province Science & Technology Award, Scientific Progress Division. Completion Unit: Kunming Institute of Botany, Product Quality Supervision & Inspection Institute of Yunnan Province Main Contributors: ZHANG Ying-Jun, YANG Chong-Ren, CHEN Ke-Ke, ZHU Hong-Tao, ZHANG Xiang-Lan, WANG Dong, SUN Wen-Tong, XU Min, Da-Fang, LIU Qing, JIANG Hong-Jian, ZHU Hong-Kun, FENG Lei

Main Contents and Impacts: The project systematically studies the chemical origins of cultivated . Camellia Sinsensis constituents of Yunnan-produced Camellia Sinensis complex may compose of Dali tea and affinis species and is (including ecological , Puerh raw tea, Puerh ripe formed by sporadic mutation and artificial selections during tea) and its affinis species, i.e. Dali tea and Porella Camellia the long-term utilization and cultivation. crassicolumna, successfully separating and identifying 79 7 dominant spawns are isolated and identified from chemical compounds. Puerin A & B, with novel structure, fermentative Puerh tea. "Puerh Starter" is developed after is isolated for the first time, and proves to be the featured studying the botanical features of spawns and optimizing constituents of Puerh ripe tea after secondary fermentation. cultivation environment. Besides, a normalized production Theine, an ellagitannin-type compound, is initially found in technology of Puerh ripe tea is created after analyzing and Dali tea, which is identified as featured constituents of Dali comparing the sensory and physicochemical properties, and tea. It also discovers that Camellia crassicolumna is without the technology has been put into application and gained caffeine and theophylline. The findings aforementioned not remarkable benefits. only explain the material basis of tea, but also give new and There are a total of 16 academic articles published distinctive resources. among which 3 articles are collected in SCI. 4 patents are With modern analysis techniques of high-pressure applied. liquid chromatography, gas chromatography, hyphenated With long-term research, the project has made mass spectrometry and spectrophotometry, a quantitative remarkable achievements and bears certain theoretical and method for analyzing chemical constituents of Puerh tea, practical value. Moreover, it brings preferable economic including catechins, caffeine, theanine, gallic acid, fragrant and social profit. The research results play a leading role in compounds, tea polyphenol and tea polysaccharide, is domestic academic field. successfully set. Besides, HPLC analysis technique is also established for synchronously conducting the quantitative analysis of gallic acid and theanine. This provides technical basis for constructing a comprehensive technological system of quality assessment of Puerh tea. Based on traditional sensory evaluation, the project first adopts computer aided technology in data collection, quantification and system integration, and establishes a new mode of comprehensive quantitative analysis of organoleptic property of tea. As a result, the project provides a new evaluation mode for tea quality assessment, brand construction and market expanding. By means of outdoor investigation together with systematic analysis and comparison of chemical components, the project adventures a proposal that Dali tea is one of the

30 5.SCIENTIFIC PUBLICATIONS AND PATENT APPLICATION

In 2009, KIB has published 258 SCI-indexed articles, among which 193 articles were published with KIB as the first author. 44 and 82 articles were Top 15% and Top 30% articles in related fields, respectively. In addition, KIB as well published 149 CSCD- indexed articles and 5 monographs (see Appendix II). In 2009, 26 national patents are applied and 9 national patents are authorized. 1 U.S. patent application has been permitted and 2 national trademark registration certificates have been achieved (see Appendix III).

6. NEW AND ONGOING NATIONAL RESEARCH PROJECTS

In 2009, there are 127 newly-added scientific research projects, including 1 candidate project of state high-tech development program; 2 national "973" projects (sub-projects); 22 NSFC projects (thereinto 1 key project; 2 NSFC-Yunnan Province key joint projects and 1 major research program); 10 scientific & technological programs of Yunnan Province (thereinto 2 major projects and 1 "Strengthening Yunnan through Science & Technology" project); 1 innovation team of Yunnan Province; 1 top talents program of Yunnan Province; 3 reserve talents programs of Yunnan Province and 2 national research projects of new medicine; 21 CAS programs (including 1 open research project of large scientific facilities and 1 young foreign scientist program); and has newly signed 11 international cooperation programs, 18 entrust projects. The total expenditure of new projects and programs has been in excess of RMB 80,000,000. "Fundamental Research on Officinal Active Substances in Endemic Plants and Microorganisms", a 973 project organized and declared by KIB in 2008, is conducted this year. "A Study on DNA Barcode of Plants with Germplasm Bank as Base" has gained the support of CAS with total expenditure of RMB 15,000,000. "Collection of Camellia & Azalea & Optimism of Botanic Garden" has obtained RMB 6,000,000 from CAS. As for transfer of scientific achievements, "EMEI Capsule", a medicine for gynecological disease, has been transferred to Yunnan Baiyao Group Co., Ltd. at a price of RMB 9,090,000. Technology Transfer Center, a cooperative construction with Yunnan Shuisong Paper Factory and Yunnan Xili Bio-Technology Co., Ltd., receives RMB 3,400,000 from the two companies aforementioned.

31 New and Ongoing Key S&T Projects Undertaken in 2009

Project Name Description Fund Fund of (Million) KIB(Million) Duration

Fundamental Research on Active Substances in Endemic 1 973 Project 30 5.87 2009-2013 Plants and Microorganisms

Hedges Construction for Sloped Lands & Development Project of Supporting 2 and Demonstration of Special Biological Resources in 5.14 1.8 2009-2010 Program Minority Inhabited Region of Hengduan Mountain

Public Experimental Center of Kunming National Biological Equipment Platform of 3 8 8 2009-2010 Industry Base NDRC

4 Evolutionism & Adaptation Mechanism of Biodiversity in Key Project of NSFC 1.7 1.02 2010-2013 Alp Ice Sheet Region and Its Response to Global Warming

Discovery and Mechanism Study of Leading Compounds NSFC—Yunnan Joint 5 1.8 1.1 2010-2013 from Pteridophyta in Southwest China Fund

Germplasm Resources Protection & Genomic Study of NSFC—Yunnan Joint 6 Comparing Function of Oil-tea Camellia, Yunnan Camellia 1.85 1.1 2010-2013 Fund Sinensis and Yunnanea.

Adaptive Origin of Temperate in Hengduan Key Project of Major 7 2 1.2 2010-2012 Mountain and Its Relationship with Environmental Transition Research Plan of NSFC

8 Transfer of Clinical Achievements of Emei Capsule Transfer 9.09 2.727 2009-

9 Co-construction of Technology Transfer Center Co-construction 3.4 3.4 2009-2011

Large Scientific 10 A Study on DNA Barcode of Plants with Germplasm Bank 15 4.5 2009-2012 as Base Facilities Special Project of Conservation and 11 Collection of & and the Sustainable Utilization 6 3 2009-2010 improvement of the specialized gardens within which they of the National are grown. Strategic Bio-resources

Important Directional 12 0.8 0.48 2009-2011 Plant Resource & Drug Development Sub-center Project, CAS

Important Directional 13 Compilation of China Great Collection –Collection of 2.5 1.5 2009-2011 Project, CAS Biology

Important Directional 14 1.5 1.5 2009-2011 Collection and Conservation of Medicinal Herbs Project, CAS

32 7.INTERNATIONAL COOPERATION AND REGIONAL EXCHANGES

Overview of International and Wild Species will play an important part in protecting global Regional Cooperation biodiversity.

In 2009, KIB has been outbound on public duty to 15 countries including Great Britain, Japan, U.S.A, etc., Comprehensive Survey of Plant involving 27 projects and 38 researchers, as well as two Diversity in Hengduan Mountain Area visits to for academic conferences, involving 8 Completed and Gained Significant researchers. Foreign visiting scholars amount to 198 Results persons. The comprehensive scientific investigation of plant KIB has also employed 7 foreign experts among who 3 diversity in Hengduan Mountain Area cooperated by Sino-US are further appointed while 4 are newly-employed. 1 foreign scientists, which lasted 6 years, was formally completed in honored professor is newly recruited and 1 Cameroonian 2009. doctor is jointly educated. In 2003, KIB and Harvard University Herbarium signed KIB successfully organizes 3 international conferences. a science and technology cooperation agreement, jointly 50 SCI-embodied articles are jointly published with implementing the cooperation project - "Biodiversity overseas institutes or scholars. Research of Plant and Fungi in Southwest China". The 34 international research projects are now in progress, project received co-finance from U.S. National Natural and 11 projects are newly added, with over RMB 12,000,000 Science Foundation (NSF) project and key international as fund. cooperation project of Chinese National Natural Science The First Forest Seeds from ICRAF Foundation. is Reserved in the Germplasm Bank of Since 2003, the Sino-US joint expedition team Wild Species successively launched five large-scale field investigations in nearly 50 counties, such as Tibet Changdu, Yunnan KIB, together with ICRAF, signed an international plant Diqing, Sichuan Liangshan, Ganzi, Aba. The expedition germplasm resources protection protocol in December, team consisted of more than 20 researchers respectively 2007. Thorough cooperation, ICRAF expects to gradually from KIB, Institute of Botany of CAS, Yunnan Normal save the important plant germplasm resources in the University, Harvard University, the Field Museum of Natural Germplasm Bank of Wild Species, so as to guarantee the History, Kochi Prefectural Makino Botanic Garden, Japan long-time safe storage of these plant germplasm resources. and other units. In the 6 years, China and U.S. scientists Besides, the both sides will further their cooperation have collected 12,000-15,000 specimens in total, more in sustainable utilization and protection of germplasm than 6,000 of which are higher plants or fungi taxa. Until resources through capacity building and informational and now, the researchers have confirmed 30 new species of technical communication. plants and fungi, built on-line query database of plant In June, 2009, the Germplasm Bank of Wild Species, images and descriptions, which is open to the scientists all received 365 specimens of wood seeds from ICRAF. Those over the world, and online Chinese Place Names Handbook, seeds were collected in 19 countries including Mexico, which provides important reference for accurately Panama, Austria, Namibia, Israel, etc. This is the second identifying plant specimen collection locations. International reception of foreign seeds since the last reception of 204 communication and research level were greatly improved specimens of seeds from Millennium Seed Bank of Kew through cooperative work and a group of outstanding Gardens in October, 2008. It marks that the Germplasm young scientists were cultivated. The wide range of Bank of Wild Species, has gradually become an international inspection makes the national research institutions and local platform of germplasm resources protection and will play an governments establish good friendship and provide scientific important role in preserving biodiversity worldwide. guidance for management and conservation of regional The cooperation between KIB and ICRAF will make biodiversity. an active contribution to protection and development The Harvard Gazette once published a report, which of global plant species resources. In the meantime, it systematically introduced the five times comprehensive promotes technological cooperation between KIB and scientific surveys of plant diversity deep in Hengduan African countries. Signing the plant germplasm resources Mountain hinterland and gave a high evaluation of this co- protection protocol shows that the Germplasm Bank of operative research. Wild Species has been ranked as the third most important germplasm bank after Svalbard Global Seed Vault in Norway and Kew Garden in Great Britain. The Germplasm Bank of

33 2009 Annual Conference of Swedish Environment Secretariat in Asia Successfully Held

From March 17th to 19th, Swedish Environment Secretariat in Asia successfully held its sixth annual conference in Kunming, which was undertaken by KIB and World Agroforestry Center. In addition to the conference delegates, the following people were also invited to attend the meeting: -Ming, Director of Yunnan Federation of Social Sciences; ZHANG Zhuang-Xin, President of Kunming Branch of CAS; Lennart Linner, the Swedish Ambassador to Thailand Ambassador; Mikael Lindstrom, the Swedish Ambassador to China Ambassador; Mia Horn af Rantzien, the executive director Swedish International Development Cooperation Agency (SIDA); Christer Holtsberg, director of the Swedish Environment Secretariat in Asia. It was demonstrated that Kunming, Yunnan Province, China, is the important developing region for , particularly for the Swedish International Cooperation Development Agency and Swedish Environment Secretariat in Asia. Examples of international cooperative projects undertaken in the past few years include cooperating with Swedish Environment Secretariat in Asia, Thailand Doctor Larson-Rabin has been working on post-doctorial Environment Institute and World Agroforestry Center study of population genetics in Horticulture Department of China Program, proposing assessment methods on good University of Wisconsin since 2007. Many of his academic environmental governance for civil society organizations, articles are published in internationally famed journals such etc. Kunming has an important role to play in the future as Plant Physiology , Plant Signaling & Behavior, etc. project development of Swedish Environment Secretariat in Asia. The successful holding of the annual conference in Talents Cultivation & Introduction Kunming laid a good foundation for the future cooperation through International Cooperation with Swedish International Cooperation Development Agency, Swedish Environment Secretariat in Asia, KIB and During 2009, KIB employed 7 foreign experts to do full- other units. time research or take charge of project management. They are Professor Kidou Yoshino from Japan, Doctor Timm Goetz First "Foreign Young Scientist Tennigkeit from German, Post-doctor Frédéric M.B. Jacque Program" Approved from , Professor Hans-deitrich Achmidt-vogt from German, Researcher Ma Jinshuang from U.S.A., Mrs Liu Qing "Foreign Young Scientist Program" is one of "Overseas from Canada and Mrs Juliet Nadeau Lu from U.S.A. Among Talents Introduction & International Talents Communication these experts, Frédéric M.B. Jacque is the first foreign post- and Cultivation Projects", which aims at bringing in excellent doctor and has successfully passed the thesis defense. foreign young scientists to finish cooperative research With the help of "Foreign Technology & Talents in KIB, and thus improves academic communication, Introduction Project" proposed by Bureau of Foreign Experts international communication and talents cultivation. Affairs, Yunnan Province, , a mycology expert from Doctor Zachary Larson-Rabin from University of New Zealand, conducts a three months joint-study which Wisconsin and Researcher LI De-Zhu from KIB jointly obtains significant achievements in endangering risks and applied "Foreign Young Scientist Program" and successfully artificial cultivation of truffle planted in Yunnan Province. obtained the fund. Doctor Larson-Rabin got A-level fund Doctor Alan Charles Hamilton, a British botanist employed of RMB 250,000 within one year. This is the first time that in FCO, is employed by KIB as honorary professor. Doctor KIB is conferred fund of this project. Doctor Larson-Rabin Hamilton is an officinal plant expert who mainly works on will conduct a genomic study on the function of bamboo, British-Sino scientific projects and greatly contributes to cooperating with prof. LI De-Zhu and Researcher Guo long-term scientific cooperation between British government Zhenhua. and KIB. Doctor Larson-Rabin was graduated from University In addition, KIB, together with Buea University of of Wisconsin at Madison in 2007, majoring in Molecular Cameroon, jointly educates 1 doctor through the CAS-TWAS Genetics. He is mainly engaged in the functional studies of Scholarship Program. morphogeny-related genes from model plant Arabidopsis. 34 China Project Seminar of Botanic with matured scientific achievements. By exhibiting the Gardens Conservation International excellent achievements, KIB showed its scientific power and introduced the new scientific products. Botanic Gardens Conservation International (BGCI), founded in 1987, is the world's largest organization for the Transformation of New Flower conservation of plant diversity and one of the three major Cultivars international environmental protection organizations. In The floral industry is a key industry in Yunnnan Province. order to further effectively conserve China's rich plant KIB, with its particular research and advantages in this diversity from a global perspective, BGCI’s China Project area, provides technical support for the development of Office was established in 2007 and 8 plant diversity local enterprises. The product competitiveness has been conservation projects have been started in China since enhanced by transfer of scientific achievements and 2008. technology. The patent right of "Tissue Culture of Late The BGCI China Project Seminar themed "the Ex-Situ Spring Banana cultivar?" (Banana is not a ) has been and In-Situ conservations of China's threatened plants transferred to Yunnan Green-land Biological Technology Co., and the integration of local communities", undertaken by Ltd with a price of RMB 100,000. The new Rhododendron Kunming Botanical Garden of KIB, was successfully held in cultivar and species of Rhododendron ‘Golden’ and Caojian Town of , Yunnnan Province of China Rhododendron erubescens Hutch, have been transferred from August 26th to 27th, 2009. The personnel taking to Yunnan Yuanyi Garden Engineering Co., Ltd with a price part in the seminar included Dr. Joachim Gratzfeld, BGCI of RMB 300,000. The enterprises will put these technical Regional Project Director; Mrs. WEN Xiang-Ying, BGCI China achievements into industrial scale production and eventually Project Manager; Mr. Sudipto Chatterjee, senior official of release them into marketplace thus bringing economic and Indian Biodiversity and Conservation Project; principals of social benefits. 7 projects of BGCI China as well as more than 30 leaders and workers of Dali State Forestry Administration, Yunlong Creation & Transformation of New County Forestry Bureau, Caojian town government, Medicine Jinshajiang River Forest Industry Council. Zhang Changqin, Yunnan Baiyao Group Co., Ltd. is a nationally well-known Rhododendron expert of KIB and Ms. Tian Ning, the KIB enterprise and a corporate champion in medicine industry international cooperation officer, were also invited to in Yunnan Province. After the successful development of participate the meeting. The Wildlife Management Office of "Gongxuening", KIB again transfers clinical achievements of Yunnan Forestry Department sent a congratulatory message "Emei" capsule to Yunnan Baiyao Group Co., Ltd at a price to the seminar, expressing the warm congratulations to the of RMB 9,090,000. This drug is now applying for approval by convening of the seminar and the sincere greetings to all SFDA, and is expected to be another innovative medicine. the participants. KIB also transfers innovation patent of "preparation During the seminar, experts and scholars conducted method of medicine for treatment and prevention of active discussions with the officers of local forestry and Osteoporosis" to Yunnan Xili Biological Technology Co., administrative departments on BGCI China Project, Ltd. The company will be responsible for the follow-up especially on the implementation and future plan of research and incubation. The medicine is now undergoing "Biodiversity assessment and conservation of woody plants development. in Zhibenshan Mountain located in Yunlong County, Dali prefecture of Yunnan Province". The success of this seminar Management of Joint-stock laid a profound foundation for long-time cooperation with Companies BGCI. KIB keeps in touch with managers in joint-stock Cooperation with Enterprises companies so as to instantly keep up with the important events and financial condition. Authorized by the legal KIB continues its work in maintaining existing representative, representative of KIB has right to attend partnerships, exploring new and potential partners and general meeting of stockholders and implement the voting taking initiatives to act as a go-between for project teams right. and enterprises. KIB has received 55 visitors and conducted KIB transfers the stock of Yunnan Zhongke Bio- 18 negotiations, actively contributing cooperation and industry Co., Ltd, drafts related contracts, agreements and technical transfer. KIB has built relationship with over application materials and completes relevant procedures. 30 enterprises, recommending scientific achievements KIB also accomplishes stock reducing, approval developed by KIB and collecting enterprises' feedback to procedure and later period finance affairs of Yunnan Green- improve the research. In 2009, 18 cooperative projects land Biological Technology Co., Ltd. (excluding cooperative projects with foreign enterprises) A survey on reform proposal and organization of KIB were newly added, 4 of which were technical transfer. wholly-owned company is launched on. On the basis of the The total contract expenditure is RMB 14,977,800. survey report and the actual situation of KIB, a proposal In accordance with the unified arrangements of CAS for establishing a state-owned asset management company Kunming, KIB participated CAS exhibition for 6 times will be submitted to the executive meeting and the workers' congress for approval. 35 8. CONSTRUCTION OF TALENTS TEAM AND SCIENTIFIC RESEARCH PLANTPORMS

Constuction of Talents Team Proceeded

Dr. is qualified for "Introducing of Overseas Excellent Talents (Hundreds of Talents Program)" wnt and NF-kappaB, which also provides the foundation of and wins financial support from the plan of high-end finding the natural innovative small molecule anti-tumour technology talents introducing of Yunnan Province. medications of novel structures and distinct activities. Dr. LI Yan is also responsible for the subjects and projects of "Hundreds of Talents Program" and "973" etc. LI Yan, the foster doctor of University and DKFZ (German Cancer Research Centre), worked in DKFZ and CCHMC (Cincinnati Children's Hospital Medical Center) Dr. Cheng-Feng is qualified for "Introducing on the post-doctoral project research from year 2001 to of Overseas Excellent Talents (Hundreds of Talents 2007, and became a researcher of Kunming Institute of Program)". Botany, Chinese Academy of Sciences in the year 2007. LI Mr. XIA Cheng-Feng, graduated with a bachelor's degree Yan qualified for "Hundreds of Talents Program" and "Plan from College of Chemistry and Molecular Engineering of of High-end Technology Talents Introducing of Yunnan Peking University in the year 1997 and obtained a Ph.D. Province" in the degree from Institute of Organic Chemistry, y e a r 2 0 0 9 . L I Chinese Academy of Sciences in the year 2002, and is Ya n ’ s r e s e a r c h dedicated into the research on the complete synthesis and demonstrates that relevant reactions of complex naturally occurring alkaloid. t h e a b n o r m i t y He had been worked as the director of the project Eli & o f s i g n a l p a t h Lilly in Sync hem Shanghai Company for a short term would cause the and worked on post-doctorate studies from the year 2004 malformation of to 2009 in the department of biochemistry of The Ohio early embryonic State University with great achievements received on development, even the feedback mechanism area of natural killer T cells, in tumour and other which series of antigen receptor molecules with different kinds of diseases immunocompetences were found and some important in adult tissues. opinions on the antigen structures and formations of T h e s e a r e t h e immune systems were put forward. He has published r e s e a r c h f r o n t s over 20 research papers on the international authoritative and hotspots in academic journals and it was in the year 2008 that he was the biomedicine and developmental biology areas both sent to Kunming Institute of Botany, Chinese Academy at home and abroad. Adopting gene silencing and other of Sciences as a researcher with the qualification for molecule and biochemistry research measures, Dr. LI Yan "Introducing of Overseas Excellent Talents" and approved for has been dedicated to approaching into wnt signal path's "Hundreds of Talents Program" regulation mechanism on the cell differentiation, polarity in the same year. The present and movement in the head and alimentary canal with her key points of the group is relative research results published as the first author or co- to research on the complete author in Nature, Genes & Development and other biology synthesis and structure magazines, which lay the foundation for understanding activity relationship of the pathogeny of some genetic diseases and seeking efficient natural products of various therapeutic methods. She is now the research group leader immunity, antiviral property of the topic on phytochemistry and western plant resources and other bioactivities, persistent utilization national key laboratory antitumor drug and also the structural filtration and mechanism of Kunming Institute of Botany, modification methodology of Chinese Academy of Sciences. The group uses the molecule pharmaceutical ingredient of and cell filtration stage to process the activity test on the sacchariferous ligands. small molecule compounds of natural product origins and by measure of biochemistry and chemical biology to research on medication mechanism and new drug actions on the basis of tumour related molecule signal paths, including 36 Dr. QIN Hong-Bo has been successfully approved by the plan of "Introducing of Overseas Excellent Talents" and is now applying for the qualification of "Hundreds of Talents Program".

ZHAO Jin-Hua

Mr. QIN Hong-Bo, graduated and obtained a bachelor's degree of pharmacy from pharmacy major pharmaceutical department of Pharmaceutical University in the year 1996. In the year 2004, he got master's degree of pharmacy from pharmacy research department of University of Toyama, and then the doctor's degree from the University of Tokyo in the year 2007. From the year 2006 to 2008, he had been worked in Medicinal Chemistry Department of Novartis Tsukuba Institute and since the year 2008, he has been worked on the methods for organic synthesis and pharmaceutical synthesis in the Medicinal Chemistry Department of Japan Shouzhi Pharmaceuticals Ltd. Recently, Dr. QIN Hong-Bo has been working on the complete synthesis research of halenaquinol, development ZHAO Jin-Hua, graduated and received the master's of asymmetric catalytic reactions area and research of degree of physiology in Sun Yat-sen University in the year hyperlipaemia therapeutic drugs. He has also published 1996 and then doctor's degree in the year 1999. He has several papers in the top magazines of the area including worked in the technological center of Shenzhen Neptunus Tetrahedron, Heterocycles, JACS .and ACIE . Bioengineering Co., Ltd. since the year 1999 as a senior researcher who is responsible for organizing and managing the new drug development of the center. He is also the natural medicine office director (senior manager) in charge of the drug research, development and daily administration and also the Secretary of Party Committee of the Company. He is responsible for establishing the national technology center laboratory of Neptunus with 863 topic and 863 leading project, NDRC New Neptunus Drup, natural drug capability building project, key break through projects of and , Shenzhen-Hong Kong Innovative Project and its financial topic projects, and also series of new drug research and development projects. He has been approved with the "Excellent Technology Talent Award of Pharmaceuticals Industry of Guangdong Province in Thirty Years of Reform and Opening-up".

37 Others Highlights academic council of the institute and the deputy director SUN Hang became a member of the educational expert In the year of 2009, one person of our institute won the group. normal project, one for the key project, one of the associate scholar and four for the western doctors in the Annual Construction of Platforms for Western Light Program. And we have been approved by the final appraisal (CHENG Yong-Xia, DU Zhi-Zhi, NIE Ze-Long) Scientific Research and the periodic investigation (XIAO Wei-Lie, LUO Xiao- Analysis and Testing Center Dong, -Bao). The analysis and testing center became the organization In 2009, we have officially taken in six postdoctors unit of the "public experimental center" approved by Yunnan and taken out three for the out-station work, and the Provincial Development and Reform Commission in the year same time, the first foreign postdoctor (Frederic Jacques) 2009. It has set up the regional service networks and 600M was successfully taken out for the work. And in the same superconducting nuclear resonance spectrometers and year, we have went through five senior scholars appraisal double focusing mass spectrometers have been put into use, procedures and four of which have been approved for the which enable the national first grade natural pharmaceutical short term cooperation research in the institute. And we chemistry researches with all the necessary large and have also been dedicated into the postdoctors development medium sized instruments and facilities. It is able to work together with China Pharmaceutical provide 35,901 pieces of atlases with an income over RMB Group Co., Ltd., Yunnan Agricultural University and Sichuan 2,220,000. Persisting in the principle of "Orienting to the Academy of Agricultural Science. institute and society and Serving the institute and society", We have organized the experimental units for the analysis and testing center have made great efforts development work of postdoctors: as the project of Ministry on the technological innovation, international cooperation of Education and Chinese Academy of Sciences "Co- and educational training aspects, and in the year 2009, it development of Postdoctors of High Education Universities successfully finished the daily testing works of the whole and Scientific Research Institutes". We are responsible for year with all its high quality services. It was responsible for the co-development work of postdoctors with 14 research testing the content of Taxol in the Taxus chinensis planting institutes of Chinese Academy of Sciences (Chemical project of Yunnan Academy of Forestry (for the quality Institute, Semiconductor Institute, Institute of evaluation) with 240 sample tests finished. It also helped Chemical Physics, Medical Institute), Peking University, the drug manufacturing factories to test the residues in , University of Science and Technology of drugs and carried out the instrumental educational practices China and over ten 985 and 211 high education universities. for 511 students from 3 higher educational schools. We have been equipped with six first tutors and six second tutor qualifications and now we have started the enrolment procedures. Declaration of professional degrees: our Herbarium institute has finished declaration on the second degree In the year 2009, the collections of KUN increased professions and the bioengineering degree has now been stably with a total number of 38,817, which ranked the approved. In the year 2010 we will officially start the highest for many years. The total collection has, as a result, enrolment with 3 candidates received already. At the same increased to about 1,300,000. The collection received time, the pharmaceutical engineering degree is now waiting over 1,139 visitors who undertook specimens reviewing. for the authorization. Over 23 batches of 1,777 specimens were on loan. And in Appraisal and adding of degrees: in compliance with the the year 2009, our staff have appraised 7,508 specimens regulations stipulated in Ph.D. & Master Degree Subject and bonded 38,492 specimens. All the label specimens Appraisal Measures of Chinese Academy of Sciences have been recored in compliance with the properties. We (Y.F.X.W.Z.(2006)No.2), will be added and attached to the have also organized or took part in 31 field studies with year 2003 Medicinal Chemistry Development Unit and year 3,511 plant specimens collected. We have also received 60 2004 Microbiology; and according to the developmental enquiries of plant specimens consultation, evaluation and 50 needs of the institute, we are declaring for the doctor's plant specimens appraisals with 50 plant expert evidences degree of biochemistry and microbiology. issued in the year 2009 on the basis of commerce, resource In the year 2009, 14 researchers were chosen as the development and administrational purpose. The Herbarium doctoral supervisors or master supervisors. And 7 doctoral staff not only do their daily management work and provide candidates including NIE Ze-Long were granted with services, but in addition, they also undertake research Year 2009 President Honorable Mention and 10 graduate activity and paper work. In the year 2009, they have students with Year 2009 Sponsorship Award. SUN Hang was published 8 academic papers, 6 of which were SCI journal conferred Zhu Li Yuehua Bonus. And researcher LI De-Zhu papers and 1 s CSCD journal paper. In recognition of this was chosen as the member of the third degree committee effort, our institute was awarded the second in the herbaria and vice chairman of the biology department, researcher appraisal by Chinese Academy of Sciences in May 2009. HAO Xiao-Jiang was chosen as the member of the third

38 Molecular Biology Experimental Center The newly established Molecular Biology Experimental Center in the year 2009 finished recording of 1,000 plant DNA extraction and 5,000 quality qualified DNA materials, data and pictures. It also received, installed and adjusted 9 large scale instruments and meters, 14 instruments operated successfully and over 1,000 people received services from us. We have also arranged 12 research groups of 50 researchers, 5 units of 10 researchers to the Center for the experimental work. Besides the daily service and work, the Center also teaches, introduces and innovate experimental technologies

Germplasm Preservation Center

Germplasm Preservation Center of the Germplasm Bank of Wild Species, continues to strengthen the wildlife germplasm collection and preservation network establishment. It has established cooperation relationship with 54 (9 of which were added in the year 2009) scientific research institutes and universities all over the country and the network in 2009 successfully provided over 10,000 germplasm information and material including 7,817 qualified germs, 5,354 samples, 2,420 DNA materials and and measures including SSR molecule markers, DNA relative samples and collection data. 4,908 germ samples sequence testing technologies, totaling 4 times by 12 were recorded and 1,440 bourgeon experiments were people. It takes part in the research projects and hosts carried out with all of the procedures completely started the national natural science fund, knowledge innovation for the preservation. It also kept 584 germs from Millenium engineering project and other four research projects and Seed Bank and World Agroforestry Center, which indicated programs in the year 2009. During this period, it has that Germplasm Protection Center has become one of the published 5 academic papers combining experimental most important platforms for the global wildlife germplasm technologies and the corresponding research results. resource protection. In the year 2009, Germplasm Preservation Center realized 45 germ practicality sharing with the national scientific research institutes and sent out about 500 plant seeding to the institute staff for scientific research and breeding. It also provides the germ activity testing services for the corresponding governmental departments. At the same time, the Center is equipped with Rotronic water activity meter, Selecta gravity separator, Sussex Ventilation dust hood, Grant temperature gradient incubator, Germany MMM illumination incubator and Air Liquid nitrogen storage system, which help to perfect the platform hardware and provide an experimental platform for other wildlife germplasm research. On the aspect of public scientific promotion, in the year 2009 the Center has received 350 visitors from both at home and abroad and took part in the British Pavilion establishing work in 2010 Shanghai Expo. Furthermore, the preservation of germplasm became the international spot again, of which Musa itinerans was chosen as the representative plant of Millennium Seed Bank.

39 Garden has received the reputed titles of "Price Credit Unit", "One Hundred Museums" of Kunming Cultural Bureau and the first group “Practical Base of Social Education “of Yunnan Educational Bureau.

Scientific Information Center Scientific & Technical Information Center is one of Horticulture Center of KIB’s Kunming the most important supporting departments of Kunming Botanic Garden Institute of Botany, Chinese Academy of Sciences, with its For the year of 2009, 12 field works were executed, goal orientated to creating a professional botany data center, and 1351 plant accession numbers of wild collections a special and national famous library and an academic basis were introduced, which include more than 560 taxa. Over with abundant support through knowledge accumulation and 200,000 pots of ornamentals were grown and used for innovation and special resource building within the institute. landscaping in the exhibition area. Around 58,990 potted The primary innovations achievements of the institute in the saplings were planted for exhibition and conservation at year 2009 are as follows: 1. In compliance with the uniform Kunming Botanical Garden (KBG). Some 1500 seedlings arrangement of the budget center and bidding procedures of critically endangered endemic Yangbi maple Acer of the central government, the institute successfully finished yangbiensis have been ex-situ conserved in KBG’s nursery. the 10 trillion times high performance computer group “Yue Sai Rhododendron Garden”, covering an area system purchasing and the installation and adjustment of of 2.2ha, was created and pre-opened. In total, 19,677 the facilities; at the same time, with the support and help individuals of 243 of rhododendron species and cultivars of the budget center, it carried out the practical training were conserved and exhibited in the garden. Among and learning class; 2. To celebrate the 60th anniversary them, 7 are cultivars with proprietary intellectual property of Chinese Academy of Sciences, the Chinese and English rights selected by hybridization by the Professor ZHANG website were transferred and series of training and learning Chang-Qin’s team. Meanwhile, the landscape of the“Rock movements were arranged; the English website information Garden”was improved, and a total of 86 rock garden plants is strengthened on the update work with an active function has been re-planted and exhibited. The Pond of 397m2 in on the promotion work; 3. Though standard treatment the Medicinal Herb Garden has been re-treated for anti- on the species resource information, the information and leakage and the concrete fences for the Medicinal Herb records of the species were completed and integrated with Garden have been replaced by hedges. The 3rd nature trail 31,985 specifies, 11,808 DNA information, 78,384 samples and 11km of 11kv electric power line have been constructed and 78,142 database were finished; the resources including in Lijiang Alpine Botanical Garden. 37,142 species information and 43,812 pictures were shared The Germplasm Nursery for the Germplasm Bank of through network, which made a great contribution to the Wild species has been created. In total, 437 important national inspection and approval; 4. The projects involved: living plant species with 49,580 individuals, which it assisted on the editing work of General Index of Chinese exceeds the five-year scientific goal of 400 species with & Latin Names of Yunnan Plants and Economic Plants, which 9,000 individuals, have been conserved. Meanwhile, the have been now been sent to Science Press for typing; it important data related to the living plant species have been assisted on the second phase building project ARP System systematically documented. Management Regulation Forming of Chinese Academy of The center has smoothly passed the inspections from Sciences; it took the building project of "Information Sharing the tourism department, price control authorities, industrial Platform"; 5. Academic communication: it successfully and commercial administrations, urban management hosted "Biological Resource Development and Cooperation department, food sanitation administrations and other High Standard Strategy Seminar to the Peripheral Countries relative local governmental departments. With the hard Around Yunnan", "Flower Technology Innovation and work and supports from the staff and security department Supporting Industrial Development Seminar", "National of KIB, around 4,915,060,000 visitors safely toured in Drug Resource Chemical Application Research Seminar" (co- Kunming Botanical Garden. The 6 themed public education hosted), "Children Caring and Science Loving" promotional activities were successfully organized and Kunming Botanical activity and "Botany Seminar botany Across the Straits".

40 IMPORTANT EVENTS 2009

January

1.12 Mr. QIAN Heng-Yi, vice secretary of Yunnan Provincial Party Committee, visited and inspected the southwestern wildlife germplasm resource library, accompanied by Prof. LI De-Zhu, director of Kunming Institute of Botany.

February

2.5 The Second International Orchid & Camellia 2.12 The work of Native Ferns and Fern Allies of Yunnan Exposition, which extended over a period of five days, China in Color edited by our researchers CHENG Xiao and was held in Dali International Exhibition Center, and JIAO Yu and published by Yunnan Science and Technology was hosted by Floral Industry Office of Yunnan Province, Press was awarded the original book publishing project Government of the Dali Bai ., award in the second "Three Hundred" prize. branches of the Orchids and Camellias of China Flower Association and co-hosted by Kunming Institute of Botany 2.17 According to the Government Information and other corresponding organizations. Notification and the departmental scores and ranks received ‘Fenyulan’,bred by Kunming Botanical Garden under from ARP news promotion management system of the Kunming Institute of Botany, with its fresh and attractive Academy, our institute ranked the 6th in the Academy colors and shapes, won the best flower golden prize (five and was granted with the advanced unit of information golden prizes in total), and Camellia reticulata ‘Dahongpao’ promotion; and was awarded as the advanced also from the botanical garden, won the silver prize. personal. Approximately 115 of the governmental information data we sent in the year 2008 were adopted 2.5 In compliance with the regulations stated in the with an accumulated score of 455, ranking us 12th in the reply F.G.B.G.J. [2008] No. 2181 "Reply to the Public Service Academy and receiving the recognition of advanced unit. Condition Building Project of the Second Group of Year 2008 In addition we sent 118 information notifications through National Biology Industrial Basis of National Development ARP news promotion management system in the year 2008 and Reform Commission", the corresponding departments and this produced a total score of 442, the 3rd within the and experts of Yunnan Provincial Development and Reform Academy and recognition as advanced new promotion unit. Commission reviewed on the "Public Experimental Center of Kunming National Biology Industrial Basis" that was 2.18 The project starting ceremony of "Basic research hosted by researchers Mr. -Ping. They thought it in Medicinal Properties of Indigenous Chinese Plants and was enforceable in accordance with the depth and quality Microorganisms" (Project No.: 2009CB522300), the national standards of the national projects in theory. key basis research development plan (973 plan) that is hosted by our institute opened in Kunming, which signifies 2.6 To strengthen the scientific and technical project that the project was officially started and went into the all- management and improve the project implement quality sided implementation stage. and outlay using efficiency, Yunnan Scientific & Technical Bureau issued the results of the year 2008 scientific and technical project inspection and outlay test. The project of "Phenchlobenpyrrone Phase I Clinical Research" carried out by researcher HAO Xiao-Jiang was approved as the best and the project of "Anti-AIDS Drug Qishile Clinical Research" by researcher CHEN Ji-Jun was also awarded.

2.9 The two technical experts Vanessa Bertenshaw (Seed Technology Specialist) and Beverly Maynard (Curation Team Supervisor) from MSB visited the institute from February 9 to 20, 2009 on invitation for the two-week seed 2.20 With approval from the degree evaluation management technology series training for our Germplasm committee of Kunming Institute of Botany, Chinese Protection Center. Academy of Sciences, it is suggested to confer 15 students including ZHANG Xue-Mei the Ph.D. degree and 3 students including ZHANG Peng-Tao the master's degree.

41 2.23 Our institute examined and approved year 2008 winners of the first prize of environment protection and "Western Light" talents sponsorship program with ZHAO science popularization works, 6 winners of the second prize, Qin-Shi granted with co-scholar project fund RMB 500,000, 9 winner of the third prize and 2 winner of the outstanding GAO Lian-Ming the key project fund RMB 350,000, ZHAO prize, 7 advanced groups and 10 advanced individuals. Pei-Ji the normal project fund RMB 250,000 and the western The science popularization work The Colorful Plant World doctor's project fund RMB 100,000 for GE Zai-Wei, LIU En- compiled by our institute's researchers GUAN Kai-Yun and De, CHEN Jia-Hui and WANG Yuan-Yuan. SHI Zong-Ming was conferred the first prize and, at the same time, researchers GUAN Kai-Yun and CHEN Gao-Huan 2.24 In compliance with the arrangement requirements were the advanced individual honor winners. on carrying out crowds' satisfaction test work stated by the practical activity leading groups from the central and 3.21 Botanical sociaty of Yunnan, China convened the provincial commissions, our institute held "further study Fourth Session of the 10th Council in Kunming, which heard on practicing scientific outlook on development activity of the Annual Sociaty's Work Final Report of Year 2008 of the crowd's satisfaction test conference" with the satisfaction president LI De-Zhu and the Annual Financial Statement rate received at 94.5%. Report of Year 2008 of the vice president YANG Yong-Ping. This meeting also discussed the procedures on how to 2.24 With the discussion of the institute party further study the Articles of Association and the Year 2009 commission, it is decided to confer 10 groups including Academy Work Plan and other topics. Academy of Opto-Electronics the honor of "the Fourth Advanced Innovation Cultural Building Unit of Chinese 3.26 The project starting conference of "Carbon Sink Academy of Sciences" and 21 comrades including YANG Jia & Biological Diversity Asset Development of Mekong "the Fourth Advanced Innovation Cultural Building Individual River Upstream" undertaken by our institute and World of Chinese Academy of Sciences". Researcher HU Hong, the Agroforestry Center successfully opened in our institute. party branch secretary of our botanical garden was granted with the advanced individual honor. 3.26 The technical transformation contract signing ceremony to Yunnan Baiyao Group Co., Ltd. opened and 2.27 The master's thesis Educational Strategies of vice director LIU Ji-Kai on behalf of our institute signed the Pedicularis of Hengduan Mountain Area of the year 2007 contract. This was selected as a result of research among graduate YU Wen-Bin submitted by our institute won the hundreds of plants with over 20 years of hard work by our Outstanding Master's Thesis Paper of the Year 2009. researcher CHEN Chang-Xiang, covering various topics, generally based on the natural plants and oriented to cure 2.28 With selections and inspections and reporting blood stasis in gynecology. to the provincial governmental leaders for approval, the people's government of the province decided to appoint Mr. ZHOU Zhe-Kun as the government counselor with a term from February 2009 to February 2014.

March 3.11 -Fang won a scholarship for academic visitor's project financing of K.C.WONG Education Foundation, Chinese Academy of Sciences of the year 2009.

3.12 The relative experts from Yunnan Provincial Science and Technology Department carried out the inspection approval on our institute's research' topic "Research on Medicine Active Ingredient and Interaction Mechanism of Alstonia-leaf", which is a key project of Yunnan Natural Science Foundation. April 3.14 LUO Xiao-Dong and CAI Xiang-Hai were granted WANG Kuan-Cheng Scholar's Contribution 4.7 The experts from Bureau of Academy-Locality Award and LU Jia-Xi Yong Scientists Award. Cooperation Chinese Academy of Sciences and Guizhou Science and Technology Department carried out inspection 3.17 With the recommendations of the provincial approval on the topic "GAP Planting, Active Ingredient and environmental scientific academy and other corresponding Quality Control of the Major Chinese Medicine of Guizhou" departments, the second "ERM-Innovation Award of that is undertaken by our institute's researcher QIU Ming- Environment Protection and Science Popularization" Hua. appraisal committee published the results including 2 42 4.7 Professor Ram P. Chaudhary from Tribhuvan De-Zhu, academician ZHOU Jun, principal -Hua, University of Nepal and Professor Ole R. Vetaas from Bergen researcher CHEN Ji-Jun and the director of Department of University of Bergen held a special academic report for our Biology of Hong Kong University of Science and Technology, teachers and students on invitation. professor ZHAN Hua-Qiang attended. The establishment of the lab will take full advantage of the unique natural 4.8 Our institute was awarded with the honor of resources of medicinal plants and talents from both sides Advanced Unit of Comprehensive Statistical Statements and improve the cooperation between the two sides on Submitting by Chinese Academy of Sciences in the year of using the resources and researching. 2008. 4.11 Year 2008 Project Cooperation Summing-up 4.8 The first Academy Informatization Evaluation Exchange Meeting opened in Lijiang, which is financially Notification Conference of CAS opened in the network supported by the southwestern wildlife germplasm resource center of CAS and our institute was ranked the 6th in the library of the country. comprehensive evaluation. 4.14 Experts from CAS carried out appraisal procedures 4.10 Led by the director of Yunnan Provincial Science on the special project "Wildlife Germplasm Resource and Technology Department and accompanied by 12 Investigate and Preservation under Specific Environment principals from the Regulation Office, Social Development of Tibet Plateau" and the execution blue prints of our Office, Basis Office, International Cooperation Office, the institute's researcher SUN Hang. The experts were satisfied research and talent training program investigation were on the annual work report. carried out in our institute. The director, LI De-Zhu, Secretary SUN Hang, vice directors LIU Ji-Kai and YANG Yong-Ping, and principals from the financial department, offices and research department took part in the conference.

4.18 The 7th Rhododendrons Exhibition of China opened in Biyun Gardern in Jiashan County, Province, where various enterprises of landscaping and Rhododendrons attended the exhibition. Some exquisite 4.10 With approvals from the director's office, it cultivated Rhododendrons and many valuable Chinese was decided to set up the second CAS Graduate College species from the genus were exhibited, The Rhododendron Commission and our researcher and doctoral supervisor Mr. flower-baskets presented by KBG’s Kunming Botanical HAO Xiao-Jiang was chosen as one of the members. Garden were widely popular with visitors. And KIB’s Professor Zhang Changqian has been selected as the vice chairman of 4.10 The signing ceremony of KIB-HKUST Joint Lab was Rhododendron Branch, China Flower Association. held in Kunming Institute of Botany, CAS, where director LI 4.19 Mr. Andrew Smith, who is the academician of Australian Academy of Science and professor of Earth and Environment Science College of the University of Adelaide, was invited to visit our institute, along with his wife Mrs. Sally Smith. During this visit, he gave a specific academic report to the scientific researchers and graduate students.

4.20 The project of "Key Technology Research of Original Part, Material Basis, Quality Evaluation System and After Fermentation of Puer Tea Plants" co-completed by Kunming Institute of Botany, Chinese Academy of Sciences and Yunnan Product Quality Supervision and Testing Center

43 passed the result committee's evaluation procedures that Management Office and Kunming Institute of were organized by Yunnan Scientific Technology Reward Botany. Office and composed of the trade experts of the country.

4.23 The experts organized by Bureau of Life Sciences and Biotechnology under Chinese Academy of Sciences had evaluated the execution plan of " Collection of Camellias & Rhododendrons and the improvement of the specialized gardens", which has being undertaken by Kunming Botanical Garden.

May

5.5 The project of "Diversity Research of Alpine Plants" jointly completed by Kunming Institute of Botany, CAS and Yunnan Normal University passed the result evaluation procedures of Yunnan Scientific Technology Reward Office.

5.8 An Award ceremony by Kunming Panlong Ciba Street Committee was held for the advanced units and 4.23 Protection of New Varieties of Plants in China individuals in the year 2008 comprehensive administration —— the 10th Anniversary Convention of China's entry into of social security and judicial administration, in which our the International Union for the Protection of New Varieties institute was granted with the honor of advanced unit and of Plants opened in Beijing, which was hosted by State researcher CAI Ming was granted with the title of advanced Intellectual Property Office of the People's Republic of individual. China, Ministry of Agriculture of the People's Republic of China and State Forestry Administration. The researcher of 5.13 The project of "Diversity Investigation, Research our institute ZHANG Chang-Qin was awarded with the title and Protection of Seed Plants in Southeast Yunnan and of national advanced individual for the protection of new Neighborhood" completed by Kunming Institute of Botany, varieties of plants. Chinese Academy of Sciences, Yunnan University and Yunnan Academy of Forestry Science and Technology passed 4.24 To further strengthen the cooperation and the result evaluation procedures given by Yunnan Provincial understanding between Yunnan Province and Chinese Science and Technology Department. Academy of Sciences on science and technology and talents training, Mr. LUO Chong-Min, the director of the Department 5.13 The project of "Artificial Propagation Promotion of of Education of Yunnan Province along with the higher Ganba and Conservation Technology Test" hosted by education delegation, including the vice director Mr. HE Fu- Kunming Institute of Botany, Chinese Academy of Sciences Sheng and ZOU Ping and the principals from ten universities and undertaken by Yunnan Baoshan Forestry Station passed in Kunming like Yunnan University and the science & the result evaluation procedures given by Yunnan Provincial technical responsible visited our institute for discussions. Science and Technology Department.

4.28 "Diversity Protection Seminar of Biology Crossing 5.15 To develop and expand the academic thoughts Border of Gaoligong Mountain" sponsored by ICIMOD of academician WU Zheng-Yi and accelerate our country's (International Centre for Integrated Mountain Development) research on the actinobiology road, "WU Zheng-Yi Academic successfully opened in our institute, with over 20 leaders Thoughts Seminar" held by Key Laboratory of Biodiversity and experts representing; ICIMOD, Forestry Department and Biogeography, Kunming Institute of Botany, CAS was of Yunnan Province, Gaoligong Mountain National Nature held in our institute. Reserve Management Bureau, Kunming Institute of Zoology, CAS, Yunnan Academy of Social Sciences, Gaoligong Mountain National Nature Reserve Management Bureau

44 5.25 In accordance with Provisional Regulations of Achievements Inspection for Doctoral Supervisors of Yunnan Province, 9 doctoral supervisors of our institute including YANG Zhu-Liang, WANG Hong, ZHAO Qin-Shi, LUO Xiao- Dong, LI Wei-Qi, GU Zhi-Jian, HU Hong, ZHANG Yin-Jun and SUN Wei-Bang passed the achievements inspection committee's evaluation hosted by corresponding experts of Yunnan Degree Committee and Yunnan Province Office of Education.

5.31 With recommendations and reviews of the relative organizations and expert committee and approved by the Director's Office of Yunnan Provincial Science and 5.15 The Year 2009 Annual Public Science Day Series Technology Department, 3 people from our institute Activities were officially opened and the activity of "Big including ZHAO Pei-Ji, SHAO Ying-Tong and Hand by Small Hand" was held. were selected as the reserve training talents of the 12th provincial young and middle-aged academic and technical 5.16 Yunnan Association of Science and Technology held pioneers. the commencement ceremony of Year 2009 Scientific & Technical Activity Week in Yunnan Science and Technology Museum and Botanical Society of Yunnan Province organized June quiz activities on the knowledge of biological diversities and health. 6.5 The Ministry of Science and Technology of the People's Republic of China issued the Decision on Giving 5.18 The project of "Research on the Novel Structure Commendation to Outstanding Contributors, Advanced of Daphniphyllum Alkaloids" hosted by our institute's Individuals and Advanced Collective in the Field S&T researcher HAO Xiao-Jiang passed the result evaluation Works to commend those collectives and individuals with procedures by Yunnan Provincial Science and Technology outstanding achievements in the field and S&T works. Department. Academician WU Zheng-Yi was conferred with the honor of "Outstanding Contributor in the Field S&T Works" and 5.19 Kunming Institute of Botany, Chinese Academy researchers SUN Hang "Advanced Individual in the Field of Sciences organized the inspection on the infrastructure S&T Works". facilities of "Yue Sai Rhododendron Garden" undertaken by Kunming Botanical Garden. “Yue Sai Rhododendron Garden” 6.8 Seven people, led by including Dr. Doug Needham, has been partly sponsored by L'Oreal (China) Co., Ltd. and including students from Longwood Garden in America visited KIB’s Kunming Botanical Gardens. The experiences and information regarding Garden maintenance and the public educational program were shared and exchanged.

5.25 To improve the comprehensive quality, standard and service level of the information publicists, the general office of the Academy held "Information Publicist Training Class of Chinese Academy of Sciences" in . 6.16 The subproject "Formulation of ARP System Combining our practical situations and experience, the Management Rules" of ARP Phase II project "Standardization vice director of the institute, Mr. GAN Fan-Yuan, exchanged Project" of Chinese Academy of Sciences that is hosted his experience and understandings on the information by our institute and joined by Institute of Policy and promotion work. Management, Chinese Academy of Sciences was officially approved.

45 6.16 The ceremony of Year 2008 Annual Yunnan on which the Institute Party Branch and Germplasm Party Awards for Science and Technology was opened in Branch and several party members were awarded with Kunming, on which the People's Government of Yunnan honors. Province commended the award of outstanding science and technology contributor of Yunnan Province to Sun Handong, 6.29 Prof. BAI Chun-Li, the Executive Vice-President who is academician of Chinese Academy of Sciences of Chinese Academy of Sciences attended the evaluation and researcher of Kunming Institute of Botany, Chinese conference for changing of leading group of the institute Academy of Sciences. and made an important speech.

6.16 The project "Systematics and Biogeography of the 6.29 Mr. Simon Appleton, former minister of Ministry Important Groups of Bambusoideae in China" of researcher of the Environment of New Zealand, visited our institute in Prof. LI De-Zhu was awarded the first prize of Science and the company of the corresponding leaders from the New Technology Award; the research achievements "Research Zealand Embassy in China and Environment Protection on the Officinal Plant Active Ingredient of Cucurbitaceae" Department of Yunnan. of researcher QIU Ming-Hua and project "(Quantum) Computational Chemistry Research" of researcher Zhu July Huajie won the second prizes. 7.1 The director general ZHANG Zhi-Bin, vice-director 6.16 Experience Exchange of Retired Official Leaders general -Hui, section chief XING Xue-Rong, DUAN Party Branch Construction of Chinese Academy of Sciences Zi-Yuan, LUO Zhi-Ping and -Ping from of Bureau & Recognition Ceremony of "Two-Advanced" was held in of Life Sciences and Biotechnology Chinese Academy of Beijing, on which the first party branch of our institute was Sciences attended "Life Sciences Development Strategy awarded with the honor of advanced party branch of retired Seminar of Western Chinese Academy of Sciences to Year official leaders. 2020" and then visited our institute for work investigation and research. 6.17 Third Session of 6th Workers' Conference of Kunming Institute of Botany was held in the lecture hall, 3F in the administration building of the institute.

6.19 The 2009 Graduate Graduation Ceremony of Kunming Institute of Botany was held in the lecture hall of the institute, attended by over 2000 people including academician ZHOU Jun, institute leaders and department leaders, supervisors, graduates, studying graduates and their families.

7.2 According to the corresponding rules stipulated in Administrative Measures of Key Laboratories of Yunnan Province, Yunnan Provincial Science and Technology Department carried out evaluations on the work situations

6.22 After preliminary assessment of the institute and reevaluation of Graduate University of Chinese Academy of Sciences, 2 students of our institutes won the title of "Three-good Pacesetter", 3 "Excellent Graduate", 24 "Three- good Student" and 5 won "Excellent Student Leader". 6.26 Kunming Branch Chinese Academy of Sciences held the Recognition Ceremony of Party Member Cadres,

46 since year 2006 of the established 20 key laboratories in 7.31 With a smooth completion on the first five- Yunnan, in which "Natural Pharmaceutical Chemistry Key year cooperation agreement, KIB-CAS and ICRAF signed Laboratory of Yunnan Province" was named the excellent in a second five-year cooperation agreement dated from the year 2009 evaluation. November, 2009 to end of October, 2014.

7.10 "Gramineae Germplasm Resource and Genomics August Innovation Group of Kunming Institute of Botany, Chinese Academy of Sciences" lead by our institute's researcher LI 8.4 Prof. TAN Tie-Niu, the vice secretary of De-Zhu was selected as the candidate of Yunnan provincial Chinese Academy of Sciences visited our institute for innovations groups. investigation and research on international cooperation and informatization construction subjects in the company 7.17 Mr. WAN Gang, 11th CPPCC vice-chairman, of Xi Jianxun, vice president of Kunming Branch Chinese Chairman of China Public Interest Party and Minister of the Academy of Sciences and other related leaders. Ministry of Science and Technology of the People's Republic of China visited Kunming Institute of Botany accompanied 8.4 The project "Feasibility Study Report of Natural by Mr. HE Duan-Qi, vice-governor of Yunnan Province and Medicine Screening Engineering Laboratory of Yunnan other relative leaders. Province" declared by our institute was replied (Y.F.G.G.J. [2009] No. 1469) by Yunnan Provincial Development and 7.20 On the basis of crowd recommendation of the Reform Commission, which was authorized to commence. national "Two-Hundred" activity and the classic situation on advance promotion works in Yunnan in the recent years, 8.11 "Kunming Institute of Botany — Institute of Yunnan Province has selected 60 people with outstanding Biochemistry and Cell Biology Shanghai Institute for contributions to the liberation of Yunnan and 60 people Biological Sciences, CAS Academic Symposium" was held with deep impressions. Prof. CAI Xi-Tao was selected as in the national key laboratory for persistent utilization of a candidate for the "60 people with deep impressions in phytochemistry and western plant resources of our institute, Yunnan since foundation of New China". which would facilitate the improvement and the cooperation relationship between our institute and IBCA on the aspects 7.29 Mr. -Ke, the general director of Guangxi of drug activity filtration, researches on mechanism of drug Science and Technology Department with the leaders and action, chemical biology and molecular biology. experts from Guangxi Science and Technology Department, Guangxi Medicinal Herb Garden, Guangxi Traditional Chinese Medical University and Guangxi Institute of Chinese Medicine & Pharmaceutical Science visited Kunming Institute of Botany for investigation and research in the company of LUO Guo-Quan, the vice director of Yunnan Provincial Science and Technology Department.

7.30 By the authority of Department of Science and Technology in Rural Areas of the Ministry of Science and Technology of the People's Republic of China, experts of Bureau of Life Sciences and Biotechnology Chinese Academy of Sciences carried out inspection approval on the project "Formulation, Integration and Sharing of Technical Regulations Specifications and Standard of Collection and Conservation of Important Wild Plant Germplasm Resources" of our institute. 8.11 Mr. LIU Qing-Mao, vice inspector of Guangdong Science and Technology Department with leaders and experts of Guangdong Science and Technology Department, Guangdong Productivity Center, Guangdong Academy of Agricultural Sciences, Botanical Garden, Chinese Academy of Sciences, Guangdong Institute of Eco-Environment and Soil Sciences, Guangdong Research Institute of Petrochemical Industry and Guangdong Fruit Research Institute visited our institute for investigation and research.

47 8.14 The party committee, labor union and retired 9.7 FANG Xin, Deputy Secretary of Party Committee worker office together hosted "'the 60th Anniversary of the of Chinese Academy of Sciences, CHEN Guang, director People's Republic of China'-Kunming Institute of Botany, of Bureau of Personnel and Education Chinese Academy Chinese Academy of Sciences" and "Entertainment & of Sciences, WANG Qin-Li, president of Kunming Branch Sports Activities for Celebrating the 60th Anniversary of the Chinese Academy of Sciences, LI Lei, Secretary of Party Institute". Committee, YANG Jun-Xing, deputy secretary and vice president, WEI Yi, head of the personnel department 8.25 Our institute held a ceremony to grant the title of and corresponding leaders from Yunnan government and honorary professor to Dr. Alan Charles Hamilton, a famous departments came to our institute to announce the new British botanist. leader group members: LI De-Zhu as the director, SUN Hang, LIU Ji-Kai and GAN Fan-Yuan as the vice directors.

9.8 "The First National smallest Population Wild Plant Protection Seminar & Plant Reintroduction Program Launching Ceremony" hosted by Kunming Institute of Botany, State Forestry Administration and Yunnan Forestry Administration was held in Kunming. KIB’s Director LI De- Zhu, Professors of SUN Wei-Bang, ZHOU Zhe-Kun, HU Hong and ZHANG Chang-Qin made special reports on the seminar. Saplings of Cyclobalanopsis sichourensis , and Manglietiastrum sinicum propagated and cultivated by Kunming Botanical Garden were transferred to the principals of the related nature reserves separately by CHEN Jian-Wei, inspector of Protection Office of State Forestry Administration, GUO Hui-Jun, vice director of Yunnan Forestry Administration and LI De-Zhu, the director of Kunming Institute of Botany. 8.31 Yunnan Press and Publication Bureau and Yunnan Association of Journal hosted the Third Excellent Journal 9.9 Lord Selborne, senator of British Parliament and Award of Yunnan, on which Acta Botanica Yunnanica of Chairman of the Board of Royal Botanic Gardens Kew, our institute was awarded the honor of "Excellent Journal visited our institute with Dr. Paul Smith, Head of MSB, Award" and "Excellent Binding Award"; and LIU AI-Qin from Professor Hugh Pritchard, head of MSB's research section the editorial department won "Outstanding Contributor" and the corresponding officials for the Chinese project. title.

September

9.2 The institute hosted the opening ceremony of graduate students, education conference, "Three-good Student Pacesetter Award", "Outstanding Students' Leader Award", "Three-good Student Award" and Outstanding Graduate Student Award Certificate.

9.3 The election at expiration of graduate students was held in the report hall of the administration building with the brand new graduate student committee founded with LIN Liang as the chairman. 9.12 Dr. FANG Xin was granted with the Year 2009 Chinese Academy of Sciences President Excellent Award. 9.5 The first group "Three-sheng Education" social practice training base authorization ceremony of Yunnan 9.14 "Yunnan China • Japan Friendly Communication and Sky of Growing Up – Three-sheng Education Forum Sodality" was held in Kunming, hosted by the Foreign Affairs hosted by Department of Education of Yunnan Province Office of the People's Government of Yunnan Province, and assisted by Kunming TV Station and the corresponding Yunnan Provincial People's Association for Friendship with activities were held in Kunming, and Kunming Institute of Foreign Countries, Yunnan Province Office of Education, Botany was selected as one of the 12 authorized units. People's Government of Yunnan Province, Kunming Institute of Botany, CAS and Yunnan Academy of Agricultural Sciences.

48 9.28 The project of "Southwestern Biology Diversity Laboratory" with an investment of RMB 220,000,000 by Chinese Academy of Sciences and the People's Government of Yunnan Province commenced construction. This laboratory is to be composed of Kunming Institute of Zoology, CAS, Kunming Institute of Botany, CAS, Xishuang Banna Tropical Botanical Garden, CAS, Yunnan University and Yunnan Agricultural University and managed by relying on Kunming Institute of Zoology, CAS.

9.15 Principal and head of Japan Toyama Central Plant Garden visited our institute.

9.16 The BGCI China’s project seminar on "Ex-situ and In-Situ Conserving China's Threatened Plants and Integration of Local Corporation Roles" hosted by BGCI and undertaken by KIB’s Botanical Garden was held in Caojian Town, Yunlong County of Dali Bai Autonomous Prefecture, Yunnan Province, China.

9.17 The first foreign post-doctor of our institute, Frédéric Jacques, successfully passed his final review. 9.29 The party committee, labor union and retired worker office together hosted "'the 60th Anniversary of the People's Republic of China'-Kunming Institute of Botany, Chinese Academy of Sciences" and "Singing Competition for Celebrating the 60th Anniversary of the Institute".

October

10.10 Sir William Ehrman, the British Ambassador in China visited Kunming Institute of Sciences on invitation of director LI De-Zhu.

9.22 GUO Jian-Hui, the secretary of the party committee of Academy of Sciences along with his colleagues, visited our institute for investigations and researches.

9.22 Yunnan Educational Health & Scientific Research Union hosted "Artistic Performance of Yunnan Educational Health & Scientific Research Union for Celebrating the 60th Anniversary of the People's Republic of China" in Kunming Grand Theater, on which chorus from our institute won the second prize and our labor union won the title of excellent 10.15 The experts from Bureau of Life Sciences and organization. Biotechnology Chinese Academy of Sciences and Bureau of Planning and Finance Chinese Academy of Sciences carried 9.25 The public affairs management standards of out project inspection and approval on the national key Kunming Institute of Botany archives and files passed the scientific engineering "Germplasm Bank of Wild Species" first level testing of Chinese Academy of Sciences. that was undertaken by Kunming Institute of Botany and Yunnan University.

49 10.26 The engineering specialties including the 11.5 Experts from Shanghai Institute of Materia construction security, finance and files of the national key Medica and from the US visited our institute for academic scientific engineering "Germplasm Bank of Wild Species" promotion and commutation at the invitation of the national with its construction undertaken by Kunming Institute key laboratory for persistent utilization of phytochemistry of Botany, Yunnan University and Kunming Institute of and western plant resources. Zoology, CAS were inspected and approved by Bureau of Planning and Finance Chinese Academy of Sciences.

November

11.2 The comprehensive building of technical transformation center undertaken by our institute was started to construct, and the corresponding leaders of our institute and the co-construction unites and departments presented in the foundation stone laying ceremony.

11.2 "The Second International Traditional Forest Knowledge and Culture Symposium" hosted by Kunming Institute of Botany, Chinese Academy of Sciences was held in Kunming and Xishuang Banna.

11.9 The third session of the 2nd general meeting of commission of the national key laboratory for persistent utilization of phytochemistry and western plant resources was successfully held in Kunming.

11.3 "Kunming Institute of Botany — Shanghai Institute for Biological Sciences, Chinese Academy of Sciences & Shanghai Jiao Tong University School of Medicine Academic Symposium" was held in our institute.

11.13 The party committee of Kunming Institute of Botany held an enlarged meeting to prepare for the party committee changing work, which was hosted by Mr. SUN Hang, Secretary of the Party Committee and attended by the party committee members, members of discipline inspection commission and the secretaries of basic level party branches.

50 11.19 The professional project completion confirmation group organized by Kunming Institute of Botany and joined by corresponding design, supervision and construction departments finished the completion confirmation work on the 7th and 8th graduate students' buildings of the institute.

11.24 The large national scientific engineering "Germplasm Bank of Wild Species" passed the state acceptance review and audit organized by National Development and Reform Commission.

December

12.7 Ministry of Education of the People's Republic of China held a conference on the subject of cooperation between the higher education universities and scientific research institutions on training doctoral candidates. And from the year 2010 on, Kunming Institute of Botany, Chinese Academy of Sciences would carry on the demonstration work to train doctorial candidates with Yunnan University.

12.14 The institute held the fourth session of 6th workers conference (extending conference) to discuss on the topic "Restructuring Scheme (draft) of Companies".

12.19 Leaders from Bureau of Personnel and Education Chinese Academy of Sciences and Kunming Branch Chinese Academy of Sciences went to Hekou, Yunnan to review the developing circumstances of "Western Light" program.

12.29 Mr. YUE Ji-Pei, assistant professor of Key Laboratory of Biodiversity and Biogeography, Kunming Institute of Botany, CAS, attended "Year 2009 Young Scientists Conference" in Dacca, capital of Bengal, which was held by BAS, TWAS and IAP together.

51 APPENDIX 1 STAFF AND STUDENTS

Director: DUAN Jun-Hong (Take the post of Deputy Division Chief LI De-Zhu since December, 2009) Deputy Directors: ZHANG Ying-Jue SUN Hang HAN Min YANG Yong-Ping (To August, 2009) LIU Ji-Kai XUAN Yu GAN Fan-Yuan GU Shuang-Hua Director Emeritus: LI Sen (From July, 2009) WU Zheng-Yi (Academician) -Juan (From July, 2009) HU Bin General Administrative Office Head: Science and Technology Information Center GAN Fan-Yuan (until December, 2009) Chief Executive: Deputy head: ZHOU Bing (Until December, 2009) QIAN Jie (Take the post of Standing Vice Director of the Member: Office from December, 2009) LIU Ai-Qin Member: ZHOU Yi-Lan TIAN Zhi-Duan (Deputy Division Chief from December, 2009) DU Ning XIONG De- Yan-Biao ZHAO Ji-Dong LI Tuo-Jing HUANG Lu-Lu LIN Na-Na WU Yan YANG Song Biogeography and Ecology Department -Wei Head: ZHOU Zhe-Kun Division of Human Resources, CPC and Deputy Head: Education Affaires PENG Hua Head: WU Shu-Guang CAS Key Laboratory of Biodiversity and Biogeography Member: Director: ZHENG Yan-Mei (Deputy Division Chief from December, SUN Hang (Concurrent post) 2009) Executive Director: ZHOU Zhe-Kun YIN Wen WU Shao-Bo Innovation Base Consultant: WU Zheng-Yi PU Ying-Dong YANG Yun-Shan (Secretary to the Academician) SONG Bo GAO Feng (From April, 2009) LI De-Zhu's Group: LI De-Zhu HE Hai-Yan WANG Hong HUA Hong-Ying XUE Chun-Ying GAO Lian-Ming Division of Science Research and Development LU Jin-Mei & Assets and Finance Management (Divided -He (Post Doctor) into Science & Technology Department ZHANG Feng-Ping (Post Doctor from September, 2009) and Assets Management Department from WANG Qun (April to September, 2009) December, 2009) LU Lu （From March, 2009) Head: LIU Pei-Gui's Group: WANG Yu-Hua LIU Pei-Gui Member: ZHANG Chang-Qin LI Zhi-Jian (Deputy Division Chief from December, 2009) -Hua MA Xiao-Qing YU Fu-Qiang YUE Yuan-Zheng SUN Hang's Group: TIAN Ning SUN Hang NI Jing-Yun NIE Ze-Long LE Ji-Pei

52 ZHANG Yong-Hong TANG Ying ZHA Hong-Guang ZHAO Hou-Tao ZHANG Zhi-Qiang (Post Doctor from June, 2009) CHEN Jian-Guo YANG Yang (From March, 2009) ZHOU Zhuo ZHANG Jian-Wen (From March, 2009) ZHU Xin YANG Zhu-Liang's Group: LUO Dong YANG Zhu-Liang HUANG Pan-Hui ZHANG Li-Fang ZHANG Ping (Post Doctor) XU La GE Zai-Wei LUO Yang LI Yan-Chun (From August, 2009) ZHAO Dong-Wei ZHOU Zhe-Kun's Group: -Hui ZHOU Zhe-Kun WU Gang CHEN Shao-Tian CAI Qing JI Yun-Heng GUO Ting CHEN Wen-Yun -Jiang ZHAN Ke-Ping (Frederic Jacques, Post Doctor, French, ZHAI Yan-Hong leaving in November, 2009) LI Guo-Feng YANG Qing-Song (Until August, 2009) HU Jin-Jin SHUI Yu-Min's Group: SHUI Yu-Min Ph.D. Students (28) CHEN Wen-Hong SHAO Shi-Cheng CAO Guo-Yan (From November, 2009) DENG Xiao-Juan WU Shun-Yu The Herbarium (KUN) -Chun PENG Hua (Curator) ZHAN Qing-Qing LIU En-De (Assistant Curator from May, 2009) XU Jin LEI Li- Xi WANG Li-Song ZHANG Ti- Xue-Dong ZHU Wei-Dong WANG Jing-Hua NIU Yang YUE Liang-Liang WANG Ling -Hui XIANG Jian-Ying JIAN Hong-Ying MA Wen-Zhang (From September, 2009) HE Jun FANG Wei AI Hong-Lian LIU Zhen-Wen (From March, 2009) ZHANG Shu XIANG Chun-Lei (From August, 2009) TANG Li-Ping Other members: ZENG Nian-Kai YANG Shi-Xiong -Feng HU Yun-Qian FENG Bang WEN Ning ZHU Xue-Tai WEN Yi-Lin XING Yao-Wu PU Chun-Xia Master's Students (30) XIA Ke XI Xue YANG Ying ZHANG Fang-Ming SU Tao LI Shu-Hong CHEN Wen-Yun SHI Xiao-Fei YU Wen-Tao XIE Xue-Dan ZHANG Jie Laboratory of Ethnobotany ZHANG Jie-Ping Director: XIE Yan-Ping YANG Yong-Ping (Concurrent post) -Jin LONG Chun-Lin's Group: YIN Zhi-Jian LONG Chun-Lin WANG Ze-Huan WANG Yue-Hu

53 HUANG Yuan LIANG Hui-Ling (Executive chief) LUO Ji-Feng LI Bo YOSHNO Hiromichi HE Yi-Neng LI Rong YU Zhen HU Guang-Wan QU Yan LONG Bo (From August, 2009) LI Xiao-Nian (From August, 2009) XU Jian-Chu's Group: Secretary: XU Jian-Chu LIN Xian YANG Xue-Fei LI Lin LI Qiao-Hong Innovation Base Consultants: GAO Fu ZHOU Jun YANG Jian-Kun -Qing (Secretary to the Academician) ZHANG Quan-Xing CHEN Ji-Jun's Group: GAO Chao CHEN Ji-Jun Other members: -Kui DAO Zhi-Ling ZHAO You-Xing -Wei ZHANG Xue-Mei WANG Jie-Ru (Going abroad on a long term basis) MA Yun-Bao XIE Hong-Yan (Going abroad on a long term basis) LUO Jie LI Dong-Sheng CHENG Yong-Xian's Group: DU Hong-Li (Until November, 2009) CHENG Yong-Xian LV Qing Master's Student (12): CHEN Xiao-Liang (From July, 2009) TANG Gui-Hua HAO Xiao-Jiang's Group: WANG Xue- Xiao-Jiang TAN Ying HE Hong-Ping -Xin LI Shun-Lin ZHUANG Hui-Fu LIU Hai-Yang LANG Rong Ni Wei YANG Xue-Qing DI Ying-Tong FANG Xin (From March, 2009) -Jie YAN Cheng-Jian (During January to July, 2009) ZHANG Yu LIU Ji-Kai's Group: ZHAO Yan-Li LIU Ji-Kai YANG Jun DING Zhi-Hui ZHANG Chan DONG Ze-Jun LI Zheng-Hui (From June, 2009) Ph. D. Student (9): WANG Fang (From March, 2009) -Yan AI Qin (From February, 2009) ZHAO Fu-Wei WEI Kun ZHAO Da-Ke LUO Xiao-Dong's Group: GU Wei LUO Xiao-Dong LI Zhuo-Qing DU Zhi-Zhi YU Hai-Ying CAI Hai- Yao QUE Ming-Hua's Group: QUE Ming-Hua Anup Sharma -Rong ZHOU Lin State Key Laboratory of Phytochemistry and HE Chun-Ling Plant Resources in West China CHEN Jian-Chao ZHANG Xian-Min Director: LIU Ji-Kai (Concurrent post) SHU Zhi-Lin LIU Jie-Qing (Post Doctor, from August, 2009) Deputy Directors: TAN Ning-Hua WANG Yi-Fen ZHAO Qin-Shi JU Peng SUN Han-Dong's Group: SUN Han-Dong Phytochemistry Analyzing and Testing Center XIAO Wei-Lie

54 PU Jian-Xin HU Jiang-Miao DU Xue LI Hai-Zhou (Having left) TAN Ning-Hua's Group: BAI Xue (From July, 2009) TAN Ning-Hua JIA Rui-Rui (Having left in March, 2009) ZHANG Yu-Mei JIA Rui-Rui Master's Students (63): JI Chang-Jiu JIANG Fu-Qiang ZENG Guang-Zhi WANG Hong-Ling PAN Xu-Lin TONG Xiao-Gang ZHANG Ying-Jun's Group: ZENG Lin-Hong ZHANG Ying-Jun YANG Yang CHEN Ke-Ke YANG Ting-Quan WANG Dong HUANG Sheng-Dian ZHU Hong-Tao LIU Ling-Li ZHANG Xiang-Lan ZHOU Yan-Ying XU Min LI Chun-Huan ZHAO Qin-Shi's Group: SONG Wei-Wu ZHAO Qin- Qian-Kun CHENG Xiao LIU Wen-Xing XU Gang PENG Li-Yan LI Xing-Yao ZHAO Yu XIAO Xiao GAO Xiu (From June, 2009) ZHANG Xiang-Yun YANG En-Hu (From October) LI Xiao-Ning ZENG Ying's Group: WANG Cui-Fang ZENG Ying JIANG Si- Pei-Ji -Xiong Ma Juan HAN Jing ZHU Hua-Jie's Group: XU Hui-Min ZHU Hua-Jie SHANG Shan-Zhai REN Jie SHEN Liang LUO Huai Rong's Group: CHEN Qian-Qian LUO Huai Rong GAO Juan CHEN Rui ZHOU Min WU Gui-Sheng ZHOU Lei HU Ying-Kai (From January, 2009) DENG Xu WU Chun-Feng (From April, 2009) DONG Liao-Bin XIE Cang-Sang (From July, 2009) WANG Peng-Cheng ZHANG Guo- Wei-Wei -Jin LI Da-Shan LI Yan's Group: HAN Wen-Xia LI Yan SHEN Lan WANG Yuan-Yuan TONG Lei SU Jia CHEN Hao LI Sheng-Hong's Group: SHI Yan-Ni LI Sheng-Hong CAO Ming-Ming LUO Qian YANG Wei YANG Ya-Rong's Group: SHI Wei YANG Ya-Rong CHENG Yuan-Yuan HE Ya-Zheng (From October, 2009) LIAO Hong-Mei XIA Cheng-Feng's Group: WANG Hai-Yan XIA Cheng-Feng KUANG Bin MA Li-Ying (From October, 2009) ZHENG Yu-Qing Other members (workers in the factory included): DONG Chuan-Fu LIU Xiao Bing SHI Yi-Ming HONG Xin (Go abroad on a long term basis) YANG Xing-Wei

55 XU Tao HE Jun FU Xiao-Li JIANG He-Zhong ZHU Li-Fang CHENG Zhong-Quan CHENG Jin-Tang LI Liang-Bo TU Dan-Dan BAI Bing WU Xiu DENG Yuan-Yuan LIU Lei DONG Ke QIAN Sheng-Yan ZOU Juan KONG Ling-Mei JI Chang-Jiu NIU Yun PENG Wen-Wen LIU Liang-Yan WU Xing-De YANG Jie YIN Xia CAO Tuan-Wu HUANG Sheng-Zhuo Ph. D. Students (57): ZHOU Bei-Dou SHEN Yong LIU Ya-Ping ZUO Ai-Xue GENG Chang-An Botanic Garden HE Kang Director: WANG Li-Jun LI De-Zhu (Concurrent post) GUO Rui-Hua Executive Director: ZHANG Yu SUN Wei-Bang LUO Shi-Hong WANG Lei Horticulture Center (Supporting system): FU Yan-Hui SUN Wei-Bang (executive chief) -Fei XIE Li-Shan ZHANG Qiang WANG Zhong-Lang ZHANG Zhen FENG Bao-Jun FANG Sheng-Tao KONG Fan-Cai LIU Rong YIN Qing (as assistant executive chief from May, 2009) JIANG Meng-Yuan YU Hong-Yuan ZHOU Zhong-Yu Yuan Hui-Kun -Qiu XU Kun ZHANG Ling LI Xing-Gui HU Jiang MAO He- Tao ZHANG Cheng-Min NIAN Yin PI Wen-Lin LU Lu LV Yuan-Lin SUN Yun ZHU Zhou YAN Yu-Xin SHEN Yun-Guang YAN Xiao-Hui XIE Jian ZHANG Hai-Bo SUN Xian-Feng -Bo KUANG Jian YIN Jun-Lin WANG Shi-Qiong LU Ren-Fu YANG Jian-Hong LI Cong-Ren CHEN Xuan-Qin LI Yue-Ming -Yan CHEN Yu HE Wen-Jun CHEN Yi-Shan -Chun FAN Jun-Tin -Hua YAN He -Kun GAO Da-Fang FENG Shi (From June, 2009) TIAN Li-Wen JI Fei (From April, 2009) PAN Zheng-Hong XI Wang (From May, 2009) WANG Kou

56 GONG Xun's Group: Ph. D. Students (19): GONG Xun WU Jiang-Chong PAN Yue-Zhi YANG Zhi-Yun YANG Yao-Wen XIONG Jiang REN Yong-Quan ZHOU Jing (From August, 2009) GUAN Zhi-Hao GUAN Kai-Yun's Group: JIANG Nan GUAN Kai-Yun WANG Zhi-Juan LI Jing-Xiu CHANG Wei LU Yuan-Xue ZHANG Le CHEN Jing ZHAO Yu-Juan LI Ai-Rong GAO Ze-Rui GU Zhi-Jian's Group: -Peng GU Zhi-Jian QIAO Qin HU Hong's Group: TIAN Wei HU Hong SHEN Min YAN Ning HU Xiao-Jian WANG Hua Sailesh Ranjitkar LI Shu-Yun HUANG Jia-Lin HUANG Jia-Lin WANG Qiu-Xia HU Shi-Jun (Post Doctor) KANG Zhi-Yu (Post Doctor) Germplasm Bank of Wild Species in GAO Qian (From August, 2009) Southwest China SUN Wei-Bang's Group: Director: SUN Wei-Bang LI De-Zhu (Concurrent post) ZHOU Yuan Deputy Director: HAN Chun-Yan LI Wei-Qi -Yang (Unitl August, 2009) Director of the Research Center: LUO Gui-Feng GAO Li-Zhi CHEN Gao (From March, 2009) Project Headquarters: XUE Rui-Juan (From March, 2009) LI De-Zhu (Manager) GAN Fan-Yuan Master's Students (24): LONG Chun-Lin DU Xin-Yu YANG Xiang-Yun -Qing ZHANG Ying-Jue WANG Chao-Bo Yu Jiao-Jun ZOU Jun-WU YANG Li-Hua Supporting System: -Ya YANG Xiang-Yun (Supervisor) CHENG Xiao-Feng ZHANG Ting AI Juan DU Yan MOU Zong-Min LI Ai-Hua ZHU Xin-Min GUO Yun-Gang PAN Rui YANG Jun-Bo (Molecular Biology Research Center from May, ZHAO Lin-Lin 2009) WANG Nian ZHANG Fu-Juan CAI Zhao-Ming LI Hong-Tao ZHANG Xin YANG Jing ZHANG Xian-Zhi ZHANG Shu-Dong JIA Jing ZHANG Zhi-Feng WANG Wen-Cai YANG Ya-Juan CUI Wei-Hua YANG Juan ZHANG Juan-Juan QIN Shao-Fa YANG Ting LIU Cheng ZHANG Rui-Rui LIN Chen WANG Guang-Yan LI Pei Xi Xue

57 SHI Chao GUO Yong-Jie ZHAO Xu-Yao HE Hua-Jie YIN Xian-Lun CAI Jie WU Zeng-Yuan ZENG Chun-Xia (From March, 2009) ZHANG Li-Na YA Ji-Dong (From July, 2009) TANG Ting LI Lian-Yi (From July, 2009) SUN Yao LI Wei-Qi's Group: LI Xiang LI Wei-Qi LI Han Ph. D. Students (23): TAO Fa-Qing WANG Dan-Dan GUO Rui-Xian MO Xin-Chun GAO Li-Zhi′s Group: ZHANG Yun GAO Li-Zhi LING Li-Zhen JIAO Jun-Ying ZHANG De-Quan YANG Li-Li REN Zong-Xin XU Ping-Zhen (Until August, 2009) YU Wen-Bin ZHAO You-Jie WEI Zhi-Dan KANG Hai-Qi (Post Doctor) DONG Li-Na HUANG Hui ZHANG Yu-Xiao ZHANG Li-Ping FAN Deng-Mei GAO Ju (Post Doctor from January, 2009) MENG Jing LIU Jiang-Peng (From August, 2009) YU Bu-Zhu MAO Shu-Yan (From July, 2009) ZHENG Guo-Wei ZHANG Dong-Ru (From September, 2009) ZHENG Yan-Ling ZHANG Qun-Jie (From July, 2009) CHEN Hong-Ying ZHANG Shao-Zhi ( Post Doctor, from January, 2009) JIA Yan-Xia -Kai ZHANG Xu-Dong YIN Ting-Shuang's Group: LIU Jie YIN Ting-Shuang LIU Yun-Long YANG Yang TONG Yan WANG Yun-Sheng ZHOU Wei XIE Lei (Post Doctor from January, 2009) Ram Chandra Poudel GUO Zhen-Hua's Group: GUO Zhen-Hua ZHANG Xue-Mei Tibetan (Qingzang) Plateau Research Institute CHEN Si-Yun (From July, 2009) ZHAO Lei (From July, 2009) at Kunming Director: YANG Yong-Ping (Concurrent post) Master′s Students (25): Members: FAN Ya-Yu HAN Xi WU Chun-Yan WEI Qi-Yun ZHU Ting ZHOU Yan HU Na YANG Yong-Ping's Group: WANG Xiao-Yan YANG Yong-Ping LIU De-Tuan DUAN Yuan-Wen YANG Hong-Mei CHEN Jia-Hui MA Peng-Fei MENG Ying ZHANG Yun-Jie LI Xiao-Li YANG Mei-Qing Ping (From June, 2009) LI Yan JIN Qiu (From June, 2009) YANG Hui SUN Shan ( From May, 2009) YU Xiao-Mei WANG Yun (From August, 2009) LIN Liang YANG Yun-Qiang (From August, 2009) -Xia BAI Xue-Gui (From October, 2009) HE Shui-Lian ZHANG Jie

58 HU Xiang-Yang's Group: KIB and Academic Committees of State and HU Xiang-Yang CAS Key Laboratories LI Wan-Sha Academic Committee of KIB TIAN Mei-Hua (Until June, 2009) Director: YIN Xian-Lun (From February, 2009) SUN Han-Dong (Academician) Members: Logistics Center CHEN Jin (Xishuangbanna Tropical Botanical Garden, Manager: Chinese Academy of Sciences) YI Yong-Sheng GONG Xun Members: GUAN Kai-Yun SONG Wei-Kui HAO Xiao-Jiang CAI Ming HU Hong WANG Kun-Sheng LI De-Zhu ZHAO Feng-Lan (Retired in May, 2009) LI Wei-Qi DONG Hai-Jun LIU Ji-Kai ZHOU Jia-Xing (Retired in March, 2009) LIU Pei-Gui FAN Xi-Kai LONG Chun-Lin FU Bao-Chong PENG Hua HU Zhao-Chang QIU Ming-Hua HUANG Li SUN Hang JIAO Yun-Ting TAN Ning-Hua LI Hai-Yan XU Jian-Chu LI Ping-Lan YANG Yong-Ping LI Ping-Yi YANG Zhu-Liang LI Ying-Hui ZHANG Zhang-Qin QIN Guo-Fu ZHANG Ke-Qin (Yunnan University) -Lin ZHANG Ya-Ping (Academician, Kunming Institute of Zoology, YANG Yong-Rui CAS) ZHONG Shun-Rong ZHANG Zhuang-Xin (Kunming Branch of CAS) BAI Bo ZHOU Zhe-Kun ZHU Hua-Jie Botanical Society of Yunnan ZHU You-Yong (Yunnan Agricultural University) Exclusive personnel: ZHAO Jun-Fen Degree Appraisal Committee of the Institute Director: Center for Mountain Ecosystems Studies LI De-Zhu Director: Members: XU Jian-Chu HAO Xiao-Jiang Members: LI Wei-QI CHEN Hua-Fang LIU Ji-Kai YAN Mei LIU Pei-Gui -Fei SUN Han-Dong (Academician) -Fang SUN Hang Tennigkeit Timm YANG Yong-Ping LI Zheng-Li ZHOU Zhe-Kun HE Jun MU Zhi-Lin Academic Committee for State Key Laboratory of YANG Hai Phytochemistry and Plant Resources in West China YANG Mei Chairman of Academic Committee: LIU Wen-Jun (From February, 2009) HAO Xiao-Jiang LU Cai-Zhen (Post Doctor from July, 2009) Vice Chairman of Academic Committee: WANG Ming-Ming SUN Han-Dong (Academician) Drschmidt Vogt（From November, 2009）Ho Myong Hyok CHEN Xiao-Ya (Academician, Shanghai Institute for (From March, 2009) Biological Sciences, CAS) Kim In Sam (From March, 2009) Pang Chol Jun (From March, 2009) Juliet Nadeau Lu (From 2009)

59 Committeeman: Honorary Posts PEI Gang (Academician, Shanghai Institute for Biological Honorary chairman of the Academic committee of CAS Key Sciences, CAS) Laboratory of Biodiversity and Biogeography: DENG Zi-Xin (Academician, Shanghai Jiao Tong University) Peter Raven (Missouri Botanical Garden, Academician of U. S. TAN Ren-Xiang ( University) National Academy of Sciences, Foreign member of CAS) TU Yong-Qiang (Academician, Lanzhou University) ZHANG Hong-Bin (Yunnan University) Honorary Professors: DU Guan-Hua (Institute of Materia Medica, Chinese Stephen Blackmore (Royal Botanic Garden Edinburgh) Academy of Medical Sciences & Peking Union Medical Chua Nam-Hai (Rockefeller University) College) Antony Galsworthy (Former British ambassador to P. R. DING Jian ( Academician, Shanghai Institute of Materia China) Medica) WEN Jun (Smithsonian Institution) JIANG Hua-Liang (Shanghai Institute of Materia Medica) Xu Jian-Ping (McMaster University, Canada) MA Da-Wei (Shanghai Institute of Organic Chemistry, CAS) Hugh W. Prichard (Royal Botanic Gardens, Kew) LI De-Zhu Alan charles hamiton (Plantlife International) LIU Ji-Kai TAN Ning-Hua Honorary Senior Horticulturalist: Advisors for the Academic Committee: David Paterson (British Royal Botanic Garden Edinburgh) ZHOU Jun (Academician) YU De-Quan (Academician, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College) YAO Xin-Sheng (Academician, Shenyang Pharmaceutical University) HONG De-Yuan ( Academician, Institute of Botany, Chinese Academy of Sciences) LIN Guo-Qiang (Academician, Shanghai Institute of Organic Chemistry, CAS)

Academic Committee for CAS Key Laboratory of Biodiversity and Biogeography Chairman: CHEN Yi-Yu ( Academician, National Natural Science Foundation of China) Vice Chairman: LI De-Zhu Committeeman: ZHANG Ya-Ping (Academician, Kunming Institute of Zoology, CAS) GU Ya-Hong (School of Life Sciences, Peking University) SHI Su-Hua (Sun Yat-Sen University) GE Song (Institute of Botany, Chinese Academy of Sciences) ZHANG Ke-Qin (Yunnan University) SUN Ge ( University) YANG Yu-Ming (Southwest Forestry University) LI Wen-Hua (Academician of Chinese Academy of Engineering, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences) SUN Hang ZHOU Zhe-Kun PENG Hua CHEN Jin (Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences) WEN Jun (American Museum of Natural History)

60 APPENDIX 2：LIST OF PUBLICATIONS

Articles cited by SCI with KIB Staff as first Author

111 Ai, Hong-Lian; Wang, Hong; Li, De-Zhu; Yang, Jun-Bo. (2009). Isolation and characterization of 13 microsatellite loci from Incarvillea mairei (), an endemic species to the Himalaya-Hengduan mountains region. Conservation Genetics 10(5): 1613-1615.

222 Chang, Xin-Liang; Jiang, Zhi-Yong; Ma, Yun-Bao; Zhang, Xue-Mei; Tsim, Karl W. K.; Chen, Ji-Jun. (2009). Two new compounds from the roots of Ligusticum chuanxiong. Journal of Asian Natural Products Research 11(9): 805-810.

333 Chen, Gao; Sun, Wei-Bang; Sun, Hang. (2009). Morphological characteristics of leaf epidermis and size variation of leaf, flower and fruit in different ploidy levels in macrostachya (Buddlejaceae). Journal of Systematics and Evolution 47(3): 231-236.

444 Chen, Gang; Wang, ; Gao, Suo; He, Hong-Ping; Li, Shun-Lin; Zhang, Jian-Xin; Ding, Jian; Hao, Xiao- Jiang. (2009). Synthesis and Bioactivity Evaluation of 3-Hydroxy-3-(phenylethynyl) indol-2-one Analogues. Journal of Heterocyclic Chemistry 46(2): 217-220.

555 Chen, Jia; Yan, Xiao-Hui; Dong, Jia-Hong; Sang, Peng; Fang, Xin; Di, Ying-Tong; Zhang, Zhong-Kai; Hao, Xiao-Jiang. (2009). Tobacco Mosaic Virus (TMV) Inhibitors from Picrasma quassioides Benn. Journal of Agricultural and Food Chemistry 57(15): 6590-6595.

666 Chen, Jian-Chao; Liu, Wu-Qing; Lu, Lu; Qiu, Ming-Hua; Zheng, Yong-Tang; Yang, Liu-Meng; Zhang, Xian- Min; Zhou, Lin; Li, Zhong-Rong. (2009). Kuguacins F-S, cucurbitane triterpenoids from . Phytochemistry 70(1): 133-140.

777 Chen, Jia-Hui; Du, Zhi-Zhi; Shen, Yue-Mao; Yang, Yong-Ping. (2009). Aporphine alkaloids from Clematis parviloba and their antifungal activity. Archives of Pharmacal Research 32(1): 3-5.

888 Chen, Wen-Hong; Shui, Yu-Min; Sima, Yong-Kang; Zhang, Rong-Mei; Wei, Zhi-Dan. (2009). Pararuellia glomerata (Acanthaceae), a new species from Yunnan, China. Botanical Studies 50(2): 261-267.

999 Chen, Xuan-Qin; Li, Yan; He, Juan; Wang, Kou; Li, Ming-Ming; Pan, Zheng-Hong; Peng, Li-Yan; Cheng, Xiao; Zao, Qin-Shi. (2009). Four New Lignans from Viburnum foetidum var. foedidum. Chemical & Pharmaceutical Bulletin 57(10): 1129-1131.

1111 Chen, Zhe; Li, Heng; Ying, Jun-Sheng. (2009). Two new species of Mahonia (Berberidaceae) from Yunnan, China. Annales Botanici Fennici 46(5): 469-473.

61 1111 Cheng, Bao Hui; Chen, Jian Chao; Qiu, Ming Hua. (2009). A new monoterpenoid indole alkaloid from Rauvolfia yunnanensis. Chinese Chemical Letters 20(10): 1221-1223.

1111 Cheng, Zhong-Quan; Yang, Dan; Liu, Yu-Qing; Hu, Jiang-Miao; Jiang, He-Zhong; Wang, Peng-Cheng; Li, Ning; Zhou, Jun; Zhao, You-Xing. (2009). Two New Phenolic Glycosides from Hypoxis aurea Lour. Bulletin of the Korean Chemical Society 30(10): 2446-2448.

1111 Deng, Xiao-Juan; Chen, Juan; Yu, Fu-Qiang; Liu, Pei-Gui. (2009). Notes on Tuber huidongense (Tuberaceae, Ascomycota), an endemic species from China. Mycotaxon 109: 189-199.

1111 Ding, Lin-Fen; Liu, Ying; Liang, Heng-Xing; Liu, Da-Peng; Zhou, Guang-Biao; Cheng, Yong-Xian. (2009). Two new terpene glucosides and antitumor agents from Centipeda minima. Journal of Asian Natural Products Research 11(8): 732-736.

1111 Fan, D.-M.; Yang, Y.-P. (2009). Altitudinal variations in flower and bulbil production of an alpine perennial, Polygonum viviparum L. (Polygonaceae). Plant Biology 11(3): 493-497.

1111 Fang, Li-Zhen; Liu, Ji-Kai. (2009). First synthesis of racemic concentricolide, an anti-HIV-1 agent isolated from the fungus Daldinia concentrica. Heterocycles 78(8): 2107-2113.

1111 Fang, Sheng-Tao; Li, Bo; Liu, Ji-Kai. (2009). Two New Withanolides from Physalis peruviana. Helvetica Chimica Acta 92(7): 1304-1308.

1111 Fang, Xin; Di, Ying-Tong; Hu, Guang-Wan; Li, Shun-Lin; Hao, Xiao-Jiang. (2009). Chemical constituents from Cipadessa cinerascens (Pellegr) Hand.-Mazz (Meliaceae). Biochemical Systematics and Ecology 37(4): 528-530.

1111 Fang, Xin; Di, Ying-Tong; Li, Chun-Shun; Geng, Zhao-Liang; Zhang, Zhen; Zhang, Yu; Lu, Yang; Zheng, Qi-Tai; Yang, Shi-Yin; Hao, Xiao-Jiang. (2009). Tetranortriterpenoids from the Leaves of Cipadessa cinerascens. Journal of Natural Products 72(4): 714-718.

2222 Fang, Xin; Zhang, Qiang; Tan, Chen-Jian; Mu, Shu-Zhen; Lu, Yang; Lu, Yong-Bin; Zheng, Qi-Tai; Di, Ying-Tong; Hao, Xiao-Jiang. (2009). Cipadonoids B-G, six new limonoids from Cipadessa cinerascens. Tetrahedron 65(36): 7408-7414.

2222 Feng, Tao; Cai, Xiang-Hai; Li, Yan; Wang, Yuan-Yuan; Liu, Ya-Ping; Xie, Ming-Jin; Luo, Xiao-Dong. (2009). Melohenines A and B, Two Unprecedented Alkaloids from Melodinus henryi. Organic Letters 11(21): 4834-4837.

2222 Feng, Tao; Cai, Xiang-Hai; Zhao, Pei-Ji; Du, Zhi-Zhi; Li, Wei-Qi; Luo, Xiao-Dong. (2009). Monoterpenoid Indole Alkaloids from the Bark of Alstonia scholaris. Planta Medica 75(14): 1537-1541.

62 2222 Feng, Tao; Li, Yan; Cai, Xiang-Hai; Gong, Xun; Liu, Ya-Ping; Zhang, Rong-Ting; Zhang, Xiang-Yun; Tan, Qin-Gang; Luo, Xiao-Dong. (2009). Monoterpenoid Indole Alkaloids from Alstonia yunnanensis. Journal of Natural Products 72(10): 1836-1841.

2222 Feng, Tao; Xu, Yan; Cai, Xiang-Hai; Du, Zhi-Zhi; Luo, Xiao-Dong. (2009). Antimicrobially Active Isoquinoline Alkaloids from Litsea cubeba. Planta Medica 75(1): 76-79.

2222 Feng, Tao; Zhang, Rong-Ting; Tan, Qin-Gang; Zhang, Xiang-Yun; Liu, Ya-Ping; Cai, Xiang-Hai; Luo, Xiao- Dong. (2009). Two New Isoquinoline Alkaloids from Litsea cubeba. Zeitschrift Fur Naturforschung Section B-a Journal of Chemical Sciences 64(7): 871-874.

2222 Gao, Lian-Ming; Li, De-Zhu. (2009). Rhododendron qiaojiaense (), a new species from Yunnan, China. Annales Botanici Fennici 46(1): 67-70.

2222 Gao, Zhu-Lin; He, Hong-Ping; Di, Ying-Tong; Fang, Xin; Li, Chun-Shun; Liu, Hai-Yang; Zhou, Qian-Lan; Mu, Quan-Zhang; Hao, Xiao-Jiang. (2009). Gracillosides A-F, six new 8, 14-seco-pregnane glycosides from Adelostemma gracillimum. Steroids 74(8): 694-700.

2222 Gao, Zhu-Lin; He, Hong-Ping; Di, Ying-Tong; Fang, Xin; Li, Chun-Shun; Zhang, Qiang; Zhao, Pei-Ji; Li, Shun-Lin; Hao, Xiao-Jiang. (2009). Three New Pregnane Glycosides from Marsdenia tinctoria. Helvetica Chimica Acta 92(9): 1775-1781.

2222 Ge, Yong-Hui; Mu, Shu-Zhen; Yang, Shi-Ying; Yang, Lu; Zhang, Jian-Xin; Ye, Wang; Hao, Xiao-Jiang. (2009). New diterpenoid alkaloids from Aconitum recemulosum Franch. Helvetica Chimica Acta 92(9): 1860-1865

3333 Geng, Chang-An; Jiang, Zhi-Yong; Ma, Yun-Bao; Luo, Jie; Zhang, Xue-Mei; Wang, Hong-Ling; Shen, Yong; Zuo, Ai-Xue; Zhou, Jun; Chen, Ji-Jun. (2009). Swerilactones A and B, Anti-HBV New Lactones from a Tradtional Chinese Herb: Swertia mileensis as a Treatment for Viral Hepatitis. Organic Letters 11(18): 4120-4123.

3333 Geng, Chang-An; Zhang, Xue-Mei; Shen, Yong; Zuo, Ai-Xue; Liu, Ji-Feng; Ma, Yun-Bao; Luo, Jia; Zhou, Jun; Jiang, Zhi-yong; Chen, Ji-Jun. (2009). Swerilactones C and D, anti-HBV New Lactones from a Traditional Chinese Herb: Swertia mileensis. Organic Letters 11(21): 4838-4841.

3333 Geng, Li-Ying; Wang, Xiang-Hua; Yu, Fu-Qiang; Deng, Xiao-Juan; Tian, Xiao-Fei; Shi, Xiao-Fei; Xie, Xue- Dan; Liu, Pei-Gui; Shen, Yu-Ying. (2009). Mycorrhizal synthesis of Tuber indicum with two indigenous hosts, and . Mycorrhiza 19(7): 461-467.

3333 Geng, Zhao-Liang; Fang, Xin; Di, Ying-Tong; Zhang, Qiang; Zeng, Ying; Shen, Yue-Mao; Hao, Xiao- Jiang. (2009). Trichilin B, a novel limonoid with highly rearranged ring system from Trichilia connaroides. Tetrahedron Letters 50(18): 2132-2134.

3333 Hao, Xiao-Jiang. (2009). Chemical and Biological Study of Spiraea japonica Complex. Progress in Chemistry 21(1): 84-99.

63 3333 He, Fei; Xiao, Wei-Lie; Pu, Jian-Xin; Wu, Ying-Li; Zhang, Hai-Bo; Li, Xiao-Nian; Zhao, Yong; Yang, Li-Bin; Chen, Guo-Qiang; Sun, Han-Dong. (2009). Cytotoxic ent-kaurane diterpenoids from Isodon sinuolata. Phytochemistry 70(11-12): 1462-1466.

3333 He, Jun; Zhou, Zhi-Mei; Weyerhaeuser, Horst; Xu, Jian-Chu. (2009). Participatory technology development for incorporating non-timber forest products into forest restoration in Yunnan, Southwest China. Forest Ecology and Management 257(10): 2010-2016.

3333 He, Juan; Chen, Xuan-Qin; Li, Ming-Ming; Zhao, Yu; Xu, Gang; Cheng, Xiao; Peng, Li-Yan; Xie, Min-Jin; Zheng, Yong-Tang; Wang, Yi-Ping; Zhao, Qin-Shi. (2009). Lycojapodine A, a Novel Alkaloid from Lycopodium japonicum. Organic Letters 11(6): 1397-1400.

3333 Hu, Guang-Wan; Lei, Li-Gong; Liu, Ke-Ming; Long, Chun-Lin. (2009). Floral development in Nymphaea tetragona (Nymphaeaceae). Botanical Journal of the Linnean Society 159(2): 211-221.

3333 Hu, Jiang-Miao; Zhao, You-Xing; Chen, Ji-Jun; Miao, Ze-Hong; Zhou, Jun. (2009). A New Spongilipid from the Freshwater Sponge Spongilla lacustris. Bulletin of the Korean Chemical Society 30(5): 1170-1172.

4444 Hu, Jiang-Miao; Zhao, You-Xing; Miao, Ze-Hong; Zhou, Jun. (2009). Chemical Components of Dendrobium polyanthum. Bulletin of the Korean Chemical Society 30(9): 2098-2100.

4444 Hu, Xu-Jia; Di, Ying-Tong; Wang, Yue-Hu; Kong, Ling-Yi; Gao, Suo; Li, Chun-Shun; Liu, Hai-Yang; He, Hong-Ping; Ding, Jian; Xie, Hua; Hao, Xiao-Jiang. (2009). Carboline Alkaloids from lii. Planta Medica 75(10): 1157-1161.

4444 Hu, Xu-Jia; Wang, Yue-Hu; Kong, Ling-Yi; He, Hong-Ping; Gao, Suo; Liu, Hai-Yang; Ding, Jian; Xie, Hua; Di, Ying-Tong; Hao, Xiao-Jiang. (2009). New phenanthrenes from Trigonostemon lii YT Chang. Tetrahedron Letters 50(24): 2917-2919.

4444 Hu, Xiang-Yang; Neill, Stevn J.; Yang, Yong-Ping; Cai, Wei-Ming. (2009). Fungal elicitor Pep-25 increases cytosolic calcium ions, H2O2 production and activates the octadecanoid pathway in Arabidopsis thaliana. Planta 229(6): 1201-1208.

4444 Huang, Yuan; Li, Yong; Hu, Xiao; Ge, Xue-Jun; Zhang, Chang-Qin; Long, Chun-Lin. (2009). Development of twelve polymorphic microsatellite loci in polyploid endangered Omphalogramma vincaeflora Franch. (). Conservation Genetics 10(3): 515-517.

4444 Huang, Yuan; Zhang, Chang-Qin; Li, De-Zhu. (2009). Low genetic diversity and high genetic differentiation in the critically endangered Omphalogramma souliei (Primulaceae): implications for its conservation. Journal of Systematics and Evolution 47(2): 103-109.

4444 Huo,Qiang; Huang Pan; Xu, Lin; Ji, Chang-Jiu; Zeng, Guang;Zhi, Jiang; Li, Hua; Fu, Xiang; Liu, Ji-Kai; Hao, Xiao-Jiang; Zhang, Ying-Jun; Tan, Ning-Hua. (2009). Screening and docking studies of natural phenolic inhibitors of carbonic anhydrase II. Science in China Series B-Chemistry 52(3): 332-337.

64 4444 Jacques, Frederic M. B. (2009). Survey of the Menispermaceae endocarps. Adansonia 31(1): 47-87.

4444 Jacques, Frederic M. B. (2009). Fossil history of the Menispermaceae (Ranunculales). Annales De Paleontologie 95(2): 53-69.

4444 Jiang, Meng-Yuan; Zhang, Ling; Dong, Ze-Jun; Liu, Ji-Kai. (2009). Two New Metabolites from Basidiomycete Sparassis crispa. Zeitschrift Fur Naturforschung Section B-a Journal of Chemical Sciences 64(9): 1087-1089.

5555 Jiang, Meng-Yuan; Zhang, Ling; Liu, Rong; Dong, Ze-Jun; Liu, Ji-Kai. (2009). Speciosins A-K, Oxygenated Cyclohexanoids from the Basidiomycete Hexagonia speciosa. Journal of Natural Products 72(8): 1405-1409.

5555 Jiang, Nan; Yu, Wen-Bin; Guan, Kai-Yun. (2009). Valid publication of the name Atalantia acuminata (Rutaceae), endemic to southwestern China and northern Vietnam. Nordic Journal of Botany 27(6): 478-478.

5555 Kong, Ning-Chuan; Zhang, Yu; Gao, Suo; Lu, Yang; Zheng, Qi-Tai; Sun, Quan-Yun; Yang, Fu-Mei; Di, Ying- Tong; Hao, Xiao-Jiang. (2009). Structural elucidation of daphniacetal A, a new oxa-cage compound isolated from Daphniphyllum macropodum Miq. Tetrahedron Letters 50(8): 957-959.

5555 Lai, Guo-Fang; Wang, Xian-You; Wang, Yi-Fen; Cao, Jian-Xin; Luo, Shi-De; Ju, Peng. (2009). Diterpenes and Diterpene Glucosides from Phlogacanthus curviflorus. Helvetica Chimica Acta 92(3): 470-480.

5555 Lei, Chun; Pu, Jian-Xin; Huang, Sheng-Xiong; Chen, Ji-Jun; Liu, Jing-Ping; Yang, Li-Bin; Ma, Yun-Bao; Xiao, Wei-Lie; Li, Xiao-Nian; Sun, Han-Dong. (2009). A class of 18(13 -> 14)-abeo-schiartane skeleton nortriterpenoids from Schisandra propinqua var. propinqua. Tetrahedron 65(1): 164-170.

5555 Li, Chun-Shun; Di, Ying-Tong; Zhang, Qiang; Zhang, Yu; Tan, Chen-Jian; Hao, Xiao-Jiang. (2009). Alkaloids from the Leaves of Daphniphyllum longeracemosum ROSENTH. Helvetica Chimica Acta 92(4): 653-659.

5555 Li, De-Zhu; Pritchard, Hugh W. (2009). The science and economics of ex situ plant conservation. Trends in Plant Science 14(11): 614-621.

5555 Li, Jun-Zhu; Qing, Chen; Chen, Chang-Xiang; Hao, Xiao-Jiang; Liu, Hai-Yang. (2009). Cytotoxicity of cardenolides and cardenolide glycosides from Asclepias curassavica. Bioorganic & Medicinal Chemistry Letters 19(7): 1956-1959.

5555 Li, Li-Mei; Li, Guo-You; Ding, Li-Sheng; Pu, Jian-Xin; Xiao, Wei-Lie; Han, Quan-Bin; Sun, Han-Dong. (2009). ent-Abietanoids and ent-Isopimaranoid Glycosides from Isodon nervosus. Helvetica Chimica Acta 92(2): 362-369.

65 5555 Li, Li-Mei; Li, Guo-You; Pu, Jian-Xin; Xiao, Wei-Lie; Ding, Li-Sheng; Sun, Han-Dong. (2009). ent-Kaurane and Cembrane Diterpenoids from Isodon sculponeatus and Their Cytotoxicity. Journal of Natural Products 72(10): 1851-1856.

6666 Li, Ming-Ming; Wang, Kou; Pan, Zheng-Hong; Chen, Xuan-Qin; Peng, Li-Yan; Li, Yan; Cheng, Xiao; Zhao, Qin-Shi. (2009). Two New Sesquiterpene Glucosides from Dennstaedtia scabra (WALL.) MOORE. Chemical & Pharmaceutical Bulletin 57(10): 1123-1125.

6666 Li, Xiao-Li; Li, Yang; Wang, Si-Feng; Zhao, Yan-Li; Liu, Ke-Chun; Wang, Xi-Min; Yang, Yong-Ping. (2009). Ingol and Ingenol Diterpenes from the Aerial Parts of Euphorbia royleana and Their Antiangiogenic Activities. Journal of Natural Products 72(6): 1001-1005.

6666 Li, Xiao-Nian; Pu, Jian-Xin; Du, Xue; Yang, Liu-Meng; An, Hui-Mei; Lei, Chun; He, Fei; Luo, Xiao; Zheng, Yong-Tang; Lu, Yang; Xiao, Wei-Lie; Sun, Han-Dong. (2009). Lignans with Anti-HIV Activity from Schisandra propinqua var. sinensis. Journal of Natural Products 72(6): 1133-1141.

6666 Li, Xiao-Xian; Zhou, Zhe-Kun. (2009). Phylogenetic studies of the core Alismatales inferred from morphology and rbcL sequences. Progress in Natural Science 19(8): 931-945.

6666 Li, Yang; Wang, Si-Feng; Zhao, Yan-Li; Liu, Ke-Chun; Wang, Xi-Min; Yang, Yong-Ping; Li, Xiao-Li. (2009). Chemical Constituents from Clematis delavayi var. spinescens. Molecules 14(11): 4433-4439.

6666 Li, Y. C.; Yang, Z. L.; Tolgor, B. (2009). Phylogenetic and biogeographic relationships of Chroogomphus species as inferred from molecular and morphological data. Fungal Diversity 38: 85-104.

6666 Li, Zhen-Jie; Chen, Jian-Chao; Sun, Yun; Song, Na-Li; Cheng, Bao-Hui; Lu, Lu; Ma, Wei-Guang; Zhou, Lin; Zhang, Xian-Min; Li, Zhong-Rong; Qiu, Ming-Hua. (2009). Three New Triterpene Saponins from Hemsleya chinensis. Helvetica Chimica Acta 92(9): 1853-1859.

6666 Liang, J. F.; Xu, J.; Yang, Z. L. (2009). Divergence, dispersal and recombination in Lepiota cristata from China. Fungal Diversity 38: 105-124.

6666 Liu, Hai-Yang; Ni, Wei; Chen, Chang-Xiang; Di, Ying-Tong; Hao, Xiao-Jiang. (2009). Two New Diterpenoid Lactams from Spiraea japonica var. ovalifolia. Helvetica Chimica Acta 92(6): 1198-1202.

6666 Liu, Jian; Mei, Wen-Li; Wu, Jiao; Zhao, You-Xing; Peng, Ming; Dai, Hao-Fu. (2009). A new cytotoxic homoisoflavonoid from Dracaena cambodiana. Journal of Asian Natural Products Research 11(2): 192-195.

7777 Liu, Jie-Qing; Wang, Cui-Fang; Chen, Jian-Chao; Tu, Shang-Hui; Gu, Hong-Fei; Hu, Wen-Xiang; Qiu, Ming- Hua. (2009). Six New Triterpenoid Glycosides from Gynostemma pentaphyllum. Helvetica Chimica Acta 92(12): 2737-2745.

66 7777 Liu, M. Q.; Deng, M.; Zhou, Z. K. (2009). Taxonomic and ecological implications of leaf cuticular morphology in , Castanea, and . Plant Systematics and Evolution 283(1-2): 111-123.

7777 Liu, Qing; Wang, Ya-Feng; Chen, Rong-Jie; Zhang, Mei-Ying; Wang, Yi-Fei; Yang, Chong-Ren; Zhang, Ying- Jun. (2009). Anti-Coxsackie Virus B3 Norsesquiterpenoids from the Roots of emblica. Journal of Natural Products 72(5): 969-972.

7777 Liu, Qing; Zhang, Ying-Jun; Yang, Chong-Ren; Xu, Mei. (2009). Phenolic Antioxidants from Green Tea Produced from Camellia crassicolumna Var. multiplex. Journal of Agricultural and Food Chemistry 57(2): 586-590.

7777 Liu, Rong; Liu, Ji-Kai. (2009). A New Neodolastane Diterpene from Cultures of the Basidiomycete Trametes corrugata. Heterocycles 78(10): 2565-2570.

7777 Liu, Rong; Zhou, Zhong-Yu; Xu, Di; Wang, Fei; Liu, Ji-Kai. (2009). A New Tricyclo [6.3.1.0(2.5)] dodecane Sesquiterpene from Cultures of the Basidiomycete Campanella junghuhnii. Helvetica Chimica Acta 92(2): 375-378.

7777 Liu, Yan-Chun; Peng, Hua. (2009). Mastixia mirocarpa (Mastixiaceae), a new species from Yunnan, China. Annales Botanici Fennici 46(6): 566-568.

7777 Liu Zhen-Wen; Deng Yun-Fei. (2009). Aristolochia wuana, a New Name in Chinese Aristolochia (Aristolochiaceae). Novon 19(3): 370-371.

7777 Lu, Lu; Chen, Jian-Chao; Nian, Yin; Sun, Yun; Qiu, Ming-Hua. (2009). Trinor-cycloartane Glycosides from the Rhizomes of Cimicifuga foetida. Molecules 14(4): 1578-1584.

7777 Lu, Lu; Fritsch, Peter W.; Wang, Hong; Li, Hong-Tao; Li, De-Zhu; Chen, Jian-Qun. (2009). Pollen morphology of Gaultheria L. and related genera of subfamily Vaccinioideae: Taxonomic and evolutionary significance. Review of Palaeobotany and Palynology 154(1-4): 106-123.

8888 Luo, Huai-Rong; Wu, Gui-Sheng; Pakstis, Andrew J.; Tong, Li; Oota, Hiroki; Kidd, Kenneth K.; Zhang, Ya- Ping. (2009). Origin and dispersal of atypical aldehyde dehydrogenase ALDH2*487Lys. Gene 425(1-2): 96-103.

8888 Luo, Jian-Rong; Ma, Qing-Yun; Zhao, You-Xing; Yi, Tie-Mei; Li, Cheng-Sen; Zhou, Jun. (2009). Palaeophytochemical Components from the Miocene-Fossil Wood of Pinus griffithii. Journal of the Chinese Chemical Society 56(3): 600-605.

8888 Luo, Xiao; Chang, Ying; Zhang, Xing-Jie; Pu, Jian-Xin; Gao, Xue-Mei; Wu, Ying-Li; Wang, Rui-Rui; Xiao, Wei-Lie; Zheng, Yong-Tang; Lu, Yang; Chen, Guo-Qiang; Zheng, Qi-Tai; Sun, Han-Dong. (2009). Schilancidilactones A and B: two novel tetranortriterpenoids with an unprecedented skeleton from Schisandra lancifolia. Tetrahedron Letters 50(43): 5962-5964.

67 8888 Ma, Xing; Xu, Jian-Chu; Luo, Yi; Aggarwal, Shiv Prasad; Li, Jia-Tong. (2009). Response of hydrological processes to land-cover and climate changes in Kejie watershed, south-west China. Hydrological Processes 23(8): 1179-1191.

8888 Mao, Chang-Li; Pan, Yue-Zhi; Wang, Jin-Feng; Gong, Xun. (2009). Isolation and characterization of microsatellite markers for Ligularia hodgsonii Hook. (Asteraceae). Conservation Genetics 10(6): 1853-1855.

8888 Mei, Ren-Qiang; Liang, Heng-Xing; Wang, Jun-Feng; Zeng, Lin-Hong; Lu, Qing; Cheng, Yong-Xian. (2009). New Seco-anthraquinone Glucosides from Rumex nepalensis. Planta Medica 75(10): 1162-1164.

8888 Mei, Ren-Qiang; Wang, Yue-Hu; Du, Guan-Hua; Liu, Guang-Ming; Zhang, Li; Cheng, Yong-Xian. (2009). Antioxidant Lignans from the of Broussonetia papyrifera. Journal of Natural Products 72(4): 621-625.

8888 Meng, Jing; Li, De-Zhu; Yi, Ting-Shuang; Yang, Jun-Bo; Zhao, Xing-Feng. (2009). Development and characterization of microsatellite loci for Rosa odorata var. gigantea Rehder & E. H. Wilson (Rosaceae). Conservation Genetics 10(6): 1973-1976.

8888 Nian, Yin; Chen, Jian-Chao; Lu, Lu; Zhang, Xian-Ming; Zhou, Lin; Qiu, Ming-Hua. (2009). Four New 9, 19-Cyclolanostane Derivatives from the Rhizomes of Cimicifuga yunnanensis HSIAO. Helvetica Chimica Acta 92(1): 112-120.

8888 Nie, Ze-Long; Sun, Hang; Meng, Ying; Wen, Jun. (2009). Phylogenetic analysis of Toxicodendron (Anacardiaceae) and its biogeographic implications on the evolution of north temperate and tropical intercontinental disjunctions. Journal of Systematics and Evolution 47(5): 416-430.

9999 Pan, Yue-Zhi; Fang, Li-Qin; Hao, Gang; Cai, Jie; Gong, Xun. (2009). Systematic positions of Lamiophlomis and Paraphlomis (Lamiaceae) based on nuclear and chloroplast sequences. Journal of Systematics and Evolution 47(6): 535-542.

9999 Pei, Sheng-Ji; Zhang, Guo-Xue; Huai, Hu-Yin. (2009). Application of traditional knowledge in forest management: Ethnobotanical indicators of sustainable forest use. Forest Ecology and Management 257(10): 2017-2021.

9999 Ren, Jie; Jiang, Ju-Xing; Li, Liang-Bo; Liao, Tou-Geng; Tian, Ren-Rong; Chen, Xu-lin; Jiang, Si-Ping; Pittman, Charles U. J.; Zhu, Hua-Jie. (2009). Assignment of the Absolute Configuration of Concentricolide - Absolute Configuration Determination of Its Bioactive Analogs Using DFT Methods.European Journal of Organic Chemistry (23): 3987-3991.

9999 Ren, Jie; Zhu, Hua-Jie. (2009). Application of Computational Chemistry in Identification for Chiral Compounds. Chemical Journal of Chinese Universities-Chinese 30(10): 1907-1918.

9999 She, Gai-Mei; Zhang, Ying-Jun; Yang, Chong-Ren. (2009). Phenolic Constituents from Balanophora laxiflora with DPPH Radical-Scavenging Activity. Chemistry & Biodiversity 6(6): 875-880.

68 9999 Shi, Ya-Na; Zhou, Yi-Ping; Long, Chun-Lin; Li, Ma-Lin; Wang, Yue-Hu; Li, Xing-Yu; Guo, Rung; Wang, Hong- Sheng. (2009). Cycloheximide Derivatives from the Fruits of dyeriana. Helvetica Chimica Acta 92(8): 1545-1549.

9999 Sun, Bao-Ling; Zhang, Chang-Qin; Lowry, Porter P. II.; Wen, Jun. (2009). Cryptic Dioecy in Nyssa yunnanensis (), A Critically Endangered Species from Tropical Eastern Asia. Annals of the Missouri Botanical Garden 96(4): 672-684.

9999 Sun, Han-Dong; Zhao, Qin-Shi. (2009). A Drug for Treating Cardio-Cerebrovascular Diseases-Phenolic Compds of Erigeron breviscapus. Progress in Chemistry 21(1): 77-83.

9999 Sun, Wei-Bang; Yin, Qing. (2009). Conservation of the Yangbi maple Acer yangbiense in China. Oryx 43(4): 461-462.

9999 Tan, Qin-Gang; Cai, Xiang-Hai Du, Zhi-Zhi; Luo, Xiao-Dong. (2009). Three Terpenoids and a Tocopherol- Related Compound from Ricinus communis. Helvetica Chimica Acta 92(12): 2762-2768.

11111Tan, Qin-Gang; Cai, Xiang-Hai Feng, Tao; Du, Zhi-Zhi; Luo, Xiao-Dong. (2009). A New Cyclooxygenase Inhibitor from Incarvillea arguta. Zeitschrift Fur Naturforschung Section B-a Journal of Chemical Sciences 64(4): 439-442.

11111Tang, An-Jun; Tian, Mei-Hua; Long, Chun-Lin. (2009). Seed dormancy and germination of three herbaceous perennial desert ephemerals from the Junggar Basin, China. Seed Science Research 19(3): 183-189.

11111Tang, A. J.; Tian, M. H.; Long, C. L. (2009). Environmental control of seed dormancy and germination in the short-lived Olimarabidopsis pumila (). Journal of Arid Environments 73(3): 385-388.

11111Tang, Gui-Hua; Sun, Chang-Song; Long, Chun-Lin; Li, Ma-Lin; Wang, Yue-Hu; Luo, Min; Wang, Hong- Sheng; Shi, Ya-Na. (2009). Sesquiterpenoids from Pilea cavaleriei subsp crenata. Bioorganic & Medicinal Chemistry Letters 19(19): 5737-5740.

11111Teng, Fei; Zhong, Hui-Min; Chen, Chang-Xiang; Liu, Hai-Yang. (2009). Four New Eudesmane Sesquiterpenoid Lactones from Chloranthus serratus. Helvetica Chimica Acta 92(7): 1298-1303.

11111Tian, Jun-Mian; Yang, Xian-Wen; Di, Ying-Tong; Ma, Yan-Lin; Li, Ling; Li, Lin; He, Hong-Ping; Hao, Xiao- Jiang. (2009). Antioxidant Lignans from Mananthes patentiflora. Planta Medica 75(5): 534-537.

11111Tian, Li-Wen; Pei, Ying; Zhang, Ying-Jun; Wang, Yi-Fei; Yang, Chong-Ren. (2009). 7-O-Methylkaempferol and -quercetin Glycosides from the Whole Plant of Nervilia fordii. Journal of Natural Products 72(6): 1057-1060.

69 11111Tian, Li-Wen; Zhang, Ying-Jun; Wang, Yi-Fei; Lai, Chi-Choi; Yang, Chong-Ren. (2009). Eucalmaidins A-E, (+)-Oleuropeic Acid Derivatives from the Fresh Leaves of maideni. Journal of Natural Products 72(9): 1608-1611.

11111Tu, Lin; Xu, Gang; Zhao, Yu; Peng, Li-Yan; He, Juan; Guo, Na; Zhao, Qin-Shi. (2009). Seven New Phenolic Glucosides from Viburnum cylindricum. Helvetica Chimica Acta 92(7): 1324-1332.

11111Wang, Fei; Cheng, Xue-Lian; Li, Ya-Ju; Shi, Song; Liu, Ji-Kai. (2009). ent-Pimarane Diterpenoids from Siegesbeckia orientalis and Structure Revision of a Related Compound. Journal of Natural Products 72(11): 2005-2008.

11111Wang, Fei; Li, Xiang-Mei; Liu, Ji-Kai. (2009). New Terpenoids from Isodon sculponeata. Chemical & Pharmaceutical Bulletin 57(5): 525-527.

11111Wang, Fei; Ren, Fu-Cai; Liu, Ji-Kai. (2009). Alstonic acids A and B, unusual 2, 3-secofernane triterpenoids from Alstonia scholaris. Phytochemistry 70(5): 650-654.

11111Wang, Fei; Xu, Yao; Liu, Ji-Kai. (2009). New geranyloxycoumarins from Toddalia asiatica. Journal of Asian Natural Products Research 11(8): 752-756.

11111Wang, Fei; Yang, Ku; Ren, Fu-Cai; Liu, Ji-Kai. (2009). Sesquiterpene lactones from Carpesium abrotanoides. Fitoterapia 80(1): 21-24.

11111Wang, Jun-Feng; Zhang, Cun-Li; Lu, Qing; Yu, Ya-Fang; Zhong, Hui-Min; Long, Chun-Lin; Cheng, Yong- Xian. (2009). Three New Diarylheptanoids from nana. Helvetica Chimica Acta 92(8): 1594-1599.

11111Wang, Li-Qin; Zhao, You-Xing; Zhou, Lu; Zhou, Jun. (2009). Lignans from montanum Markgr. f. megalocarpua. Chemistry of Natural Compounds 45(3): 424-426.

11111Wang, Peng-Cheng; Hu, Jiang-Miao; Ran, Xin-Hui ;Chen, Zhong-Quan; Jiang, He-Zhong; Liu, Yu-Qing; Zhou, Jun; Zhao, You-Xing. (2009). Iridoids and Sesquiterpenoids from the Roots of Valeriana officinalis. Journal of Natural Products 72(9): 1682-1685.

11111Wang, Wei; Zeng, Shu-Fen; Yang, Chong-Ren; Zhang, Ying-Jun. (2009). A New Hydrolyzable Tannin from Balanophora harlandii with Radical-Scavenging Activity. Helvetica Chimica Acta 92(9): 1817-1822.

11111Wang, Xiang-Hua; Liu, Pei-Gui. (2009). A type study of Lactarius sakamotoi and its presence in China. Cryptogamie Mycologie 30(1): 45-51.

70 11111Wang, Xiang-Hua; Yang, Zhu-Liang; Li, Yan-Chun; Knudsen, Henning; Liu, Pei-Gui. (2009). Russula griseocarnosa sp. nov. (Russulaceae, Russulales), a commercially important edible mushroom in tropical China: mycorrhiza, phylogenetic position, and taxonomy. Nova Hedwigia 88(1-2): 269-282.

11111Wang, Xue-Qin; Huang, Yuan; Long, Chun-Lin. (2009). Isolation and Characterization of Twenty-four Microsatellite Loci for Franch. (Ericaceae). Hortscience 44(7): 2028-2030.

11111Wang, Yue-Hu; Long, Chun-Lin; Yang, Fu-Mei; Wang, Xi; Sun, Qian-Yun; Wang, Hong-Sheng; Shi, Ya- Na; Tang, Gui-Hua. (2009). Pyrrolidinoindoline Alkaloids from Selaginella moellendorfii. Journal of Natural Products 72(6): 1151-1154.

11111Wang, Yun-Song; He, Hong-Pin; Yang, Jing-Hua; Di, Ying-Tong; Tan, Ning-Hua; Hao, Xiao-Jiang. (2009). Clausenain B, a Phenylalanine-rich Cyclic Octapeptide from Clausena anisum-olens. Journal of the Brazilian Chemical Society 20(3): 478-U105.

11111Weckerle, Caroline S.; Huber, Franz K.; Yang, Yong-Ping. (2009). A New Hysteranthous Species of Chelonopsis (Lamiaceae) from Southwest China. Novon 19(4): 552-558.

11111Weckerle, Caroline S.; Ineichen, Robert; Huber, Franz K.; Yang, Yong-Ping. (2009). Mao's heritage: Medicinal plant knowledge among the Bai in Shaxi, China, at a crossroads between distinct local and common widespread practice. Journal of Ethnopharmacology 123(2): 213-228.

11111Wei, Hai-Lei; Lei, Li-Ping; Liu, Shuo; Xia, Zhen-Yuan; Liu, Xing-Zhong; Liu, Pei-Gui. (2009). PanB is involved in nicotine metabolism in Pseudomonas putida. International Biodeterioration & Biodegradation 63(8): 988-992.

11111Wu, Ding; Gao, Lian-Ming; Moeller, Michael. (2009). Taxonomic notes on Parnassia section Saxifragastrum (Parnassiaceae) from China. Annales Botanici Fennici 46(6): 559-565.

11111Xia, Cheng-Feng; Zhang, Wen-Peng; Zhang, Ya-Long; Chen, Wen-Lan; Nadas, Janos; Severin, Ryan; Woodward, Robert; Wang, Bin; Wang, Xin; Kronenberg, Mitchell; Wang, Peng-G. (2009). The Roles of 3 ' and 4 ' Hydroxy Groups in alpha-Galactosylceramide Stimulation of Invariant Natural Killer T Cells. Chemmedchem 4(11): 1810-1815.

11111Xia, Cheng-Feng; Zhang, Wen-Peng; Zhang, Ya-Long; Woodward, Robert L.; Wang, Jin-Hua; Wang, Peng-G. (2009). Facile synthesis of biotin-labelled alpha-galactosylceramide as antigen for invariant natural killer T cells. Tetrahedron 65(32): 6390-6395.

11111Xia, Ke; Su, Tao; Liu, Yu-Sheng (Christopher); Xing, Yao-Wu; Jacques, Frederic M. B.; Zhou, Zhe-Kun. (2009). Quantitative climate reconstructions of the late Miocene Xiaolongtan megaflora fromYunnan, southwest China. Palaeogeography Palaeoclimatology Palaeoecology 276(1-4): 80-86.

11111Xiang, Chun-Lei; Liu, Zhen-Wen; Xu, Jin; Peng, Hua. (2009). Validation of the Name Chelonopsis chekiangensis (Lamiaceae), a Species from Eastern China. Novon 19(1): 133-134.

71 11111Xiang, Chun-Lei; Peng, Hua. (2009). Validation of Scrophularia macrocarpa (Scrophulariaceae) endemic to southwestern China. Nordic Journal of Botany 27(5): 379-380.

11111Xiao, Wei-Lie; Gong, Yan-Qing; Wang, Rui-Rui; Weng, Zhi-Ying; Luo, Xiao; Li, Xiao-Nian; Yang, Guang- Yu; He, Fei; Pu, Jian-Xin; Yang, Liu-Meng; Zheng, Yong-Tang; Lu, Yang; Sun, Han-Dong. (2009). Bioactive Nortriterpenoids from Schisandra grandiflora. Journal of Natural Products 72(9): 1678-1681.

11111Xie, Bai-Bo; Liu, Hai-Yang; Ni, Wei; Chen, Chang-Xiang. (2009). Ypsilandrosides C-G, five new spirostanol saponins from Ypsilandra thibetica. Steroids 74(12): 950-955.

11111Xu, Di; Sheng, Yu; Zhou, Zhong-Yu; Liu, Rong; Leng, Ying; Liu, Ji-Kai. (2009). Sesquiterpenes from Cultures of the Basidiomycete Clitocybe conglobata and Their 11 beta-Hydroxysteroid Dehydrogenase Inhibitory Activity. Chemical & Pharmaceutical Bulletin 57(4): 433-435.

11111Xu, Gang; Peng, Li-Yan; Tu, Lin; Li, Xiao-Li; Zhao, Yu; Zhang, Peng-Tao; Zhao, Qin-Shi. (2009). Three New Diterpenoids from Salvia przewalskii MAXIM. Helvetica Chimica Acta 92(2): 409-413.

11111Xu, Jian-Chu; Grumbine, R. Edward; Shrestha, Arun; Eriksson, Mats; Yang, Xue-Fei; Wang, Yun; Wilkes, Andreas. (2009). The Melting Himalayas: Cascading Effects of Climate Change on Water, Biodiversity, and Livelihoods. Conservation Biology 23(3): 520-530.

11111Xu, Jun-Ju; Tan, Ning-Hua; Chen, Yi-Shan; Pan, Xu-Lin; Zeng, Guang-Zhi; Han, Hong-Jin; Ji, Chang-Jiu; Zhu, Mei-Ju. (2009). Three Unusual New Sesquiterpenes from Alpinia oxyphylla. Helvetica Chimica Acta 92(8): 1621-1625.

11111Xu, Jun-Ju; Tan, Ning-Hua; Xiong, Jiang; Adebayo, Abiodun Humphrey; Han, Hong-Jin; Zeng, Guang-Zhi; Ji, Chang-Jiu; Zhang, Yu Mei; Zhu, Mei-Ju. (2009). Oxyphyllones A and B, novel sesquiterpenes with an unusual 4, 5-secoeudesmane skeleton from Alpinia oxyphylla. Chinese Chemical Letters 20(8): 945-948.

11111Xu, Min; Litaudon, Marc; Krief, Sabrina; Martin, Marie-Therese; Kasenene, John; Kiremire, Bernard; Dumontet, Vincent; Gueritte, Francoise. (2009). Ugandenial A, a New Drimane-type Sesquiterpenoid from Warburgia ugandensis. Molecules 14(10): 3844-3850.

11111Xu, Min; Yang, Chong-Ren; Zhang, Ying-Jun. (2009). Minor antifungal aromatic glycosides from the roots of Gentiana rigescens (Gentianaceae). Chinese Chemical Letters 20(10): 1215-1217.

11111Xu, Min; Zhang, Ming; Zhang, Ying-Jun; Yang, Chong-Ren. (2009). New Acylated Secoiridoid Glucosides from Gentiana straminea (Gentianaceae). Helvetica Chimica Acta 92(2): 321-327.

11111Xue, Chun-Ying; Li, De-Zhu; Wang, Qing-Zhong. (2009). Application of LightCycler Polymerase Chain Reaction and Melting Curve Analysis to the Authentication of the Traditional Chinese Medicinal Plant Cimicifuga foetida. Planta Medica 75(8): 873-875.

72 11111Xue, C. Y.; Xue, H. G.; Li, D. Z. (2009). Population structure and gene flow among wild populations of the Saussurea involucrate based on chloroplast DNA sequences. Planta Medica 75(9): 929-929.

11111Xue, C. Y.; Xue, H. G.; Li, D. Z. (2009). Authentication of the traditional Chinese medicinal plant Saussurea involucrate using enzyme-linked immunosorbent assays (ELISA). Planta Medica 75(9): 995-995.

11111Yan, He; Pan, Xu-Lin; Tan, Ning-Hua; Fan, Jun-Ting; Zeng, Guang-Zhi; Han, Hong-Jin. (2009). 2D-and 3D-QSAR studies on 54 anti-tumor Rubiaceae-type cyclopeptides. European Journal of Medicinal Chemistry 44(9): 3425-3432.

11111Yan, Jian; Sun, Li-Rong; Wu, Gui-Sheng; Yi, Ping; Yang, Fu-Mei; Zhou, Lin; Zhang, Xian-Min; Li, Zhong- Rong; Yang, Xiao-Sheng; Luo, Huai-Rong; Qiu, Ming-Hua. (2009). Rational design and synthesis of highly potent anti-acetylcholinesterase activity huperzine A derivatives. Bioorganic & Medicinal Chemistry 17(19): 6937-6941.

11111Yan, Jian; Sun, Li-Rong; Zhang, Xian-Ming; Li, Zhong-Rong; Zhou, Lin; Qiu, Ming-Hua. (2009). Serratene Triterpenoids from Palhinhaea cernua var. sikkimensis. Chemical & Pharmaceutical Bulletin 57(12): 1381-1384.

11111Yan, Yu-Xin; Hu, Xiao-Dong; Chen, Jian-Chao; Sun, Yun; Zhang, Xian-Min; Qing, Chen; Qiu, Ming-Hua. (2009). Cytotoxic Triterpenoid Alkaloids from Buxus microphylla. Journal of Natural Products 72(2): 308-311.

11111Yang, Chun-Yan; Huang, Yuan; Long, Chun-Yin. (2009). Isolation and Characterization of 17 Polymorphic Microsatellite Loci for Musella lasiocarpa (Musaceae). Hortscience 44(7): 2041-2042.

11111Yang, Guang-Yu; Fen, Wei-Bo Lei, Chun; Xiao, Wei-Lie; Sun, Han-Dong. (2009). Study on Determination of Pentacyclic Triterpenoids in Chaenomeles by HPLC-ELSD. Journal of Chromatographic Science 47(8): 718-722.

11111Yang, Guang-Yu; Fen, Wei-Bo; Lei, Chun; Xiao, Wei-Lie; Sun, Han-Dong. (2009). Study on solid phase extraction and graphite furnace atomic absorption spectrometry for the determination of nickel, silver, cobalt, copper, cadmium and lead with MCI GEL CHP 20Y as sorbent. Journal of Hazardous Materials 162(1): 44-49.

11111Yang, Jing; Wu, Jiang-Chong; Gu, Zhi-Jian. (2009). Karyomorphology of three species in Dipentodon (), (Celastraceae), and Tapiscia (Tapisciaceae) of the order and their phylogenetic implications. Journal of Systematics and Evolution 47(4): 291-296.

11111Yang, Jun-Bo; Li, Hong-Tao; Li, De-Zhu; Liu, Jie; Gao, Lian-Ming. (2009). Isolation and Characterization of Microsatellite Markers in the Endangered Species Taxus wallichiana Using the FIASCO Method. Hortscience 44(7): 2043-2045.

11111Yang, Jun-Bo; Yang, Jing; Li, Hong-Tao; Zhao, Yu; Yang, Shi-Xiong. (2009). Isolation and characterization of 15 microsatellite markers from wild tea plant () using FIASCO method. Conservation Genetics 10(5): 1621-1623.

73 11111Yang, Qing-Song; Chen, Wen-Yun; Xia, Ke; Zhou, Zhe-Kun. (2009). Climatic envelope of evergreen sclerophyllous and their present distribution in the eastern Himalaya and Hengduan Mountains. Journal of Systematics and Evolution 47(3): 183-190.

11111Yang, Shun-Li; Liu, Xi-Kui; Wu, Hui; Wang, Hai-Bo; Qing, Chen. (2009). Steroidal saponins and cytoxicity of the wild edible vegetable-Smilacina atropurpurea. Steroids 74(1): 7-12.

11111Yang, Xiao-Long; Xie, Zheng-Hong; Jiang, Xian-Jun; Huang, Yan-Bing; Liu, Ji-Kai. (2009). A New Acridone Alkaloid from integerrimum. Chemical & Pharmaceutical Bulletin 57(7): 734-735.

11111Yang, Xian-Wen; He, Hong-Ping; Du, Zhi-Zhi; Liu, Hai-Yang; Di, Ying-Tong; Ma, Yan-Lin; Wang, Fang; Lin, Hua; Zuo, Yi-Qing; Li, Ling; Hao, Xiao-Jiang. (2009). Tarennanosides A-H, Eight New Lignan Glucosides from Tarenna attenuata and Their Protective Effect on H2O2-Induced Impairment in PC12 Cells. Chemistry & Biodiversity 6(4): 540-550.

11111Yang, Yang; Sun, Hang. (2009). The Bracts of Saussurea velutina (Asteraceae) Protect from Fluctuating Weather at High Elevations of the Hengduan Mountains, Southwestern China. Arctic Antarctic and Alpine Research 41(4): 515-521.

11111Yuan, Lin; Lin, Xiang; Zhao, Pei-Ji; Ma, Juan; Huang, Yao-Jian; Shen, Yue-Mao. (2009). New Polyketides from Endophytic Diaporthe sp XZ-07. Helvetica Chimica Acta 92(6): 1184-1190.

11111Yuan, Lin; Ma, Juan, Wang, Ting; Li, Guo-Hong; Shen, Yue-Mao; Zhao ,Pei-Ji. (2009). Chemical Constituents from Endophytic Phomopsis sp Lz42 of Maytenus hookeri. Chemical Journal of Chinese Universities-Chinese 30(1): 78-81.

11111Yuan, Lin; Zhao, Pei-Ji; Ma, Juan; Lu, Chun-Hua; Shen, Yue-Mao. (2009). Labdane and Tetranorlabdane Diterpenoids from Botryosphaeria sp MHF, an Endophytic fungus of Maytenus hookeri. Helvetica Chimica Acta 92(6): 1118-1125.

11111Yue, Ji-Pei; Sun, Hang; Baum, David A.; Li, Jian-Hua; Al-Shehbaz, Ihsan A.; Ree, Richard. (2009). Molecular phylogeny of Solms-laubachia (Brassicaceae) s.l., based on multiple nuclear and plastid DNA sequences, and its biogeographic implications. Journal of Systematics and Evolution 47(5): 402-415.

11111Zeng, Guang-Zhi; Tan, Ning-Hua; Ji, Chang-Jiu; Fan, Jun-Ting; Huang, Huo-Qiang; Han, Hong-Jin; Zhou, Guang-Biao. (2009). Apoptosis Inducement of Bigelovin from Inula -aquatica on Human Leukemia U937 Cells. Phytotherapy Research 23(6): 885-891.

11111Zhang, Da-Cai; Boufford, David E.; Ree, Richard H.; Sun, Hang. (2009). The 29 degrees N latitudinal line: an important division in the Hengduan Mountains, a biodiversity hotspot in southwest China. Nordic Journal of Botany 27(5): 405-412.

11111Zhang, Da-Cai; Zhang, Yong-Hong; Boufford, David E.; Sun, Hang. (2009). Elevational patterns of species richness and endemism for some important taxa in the Hengduan Mountains, southwestern China. Biodiversity and Conservation 18(3): 699-716.

74 11111Zhang, Jian-Wen; Nie, Ze-Long; Sun, Hang. (2009). Cytological study on the genus Syncalathium (Asteraceae-Lactuceae), an endemic taxon to alpine scree of the Sino-Himalayas. Journal of Systematics and Evolution 47(3): 226-230.

11111Zhang, Ling; Shen, Yu; Zhu, Hua-Jie; Wang, Fei; Leng, Ying; Liu, Ji-Kai. (2009). Pentanol derivatives from basidiomycete Catathelasma imperiale and their 11 beta-hydroxysteroid dehydrogenases inhibitory activity. Journal of Antibiotics 62(5): 239-242.

11111Zhang, Lan-Sheng; Li, Zhen; Mei, Ren-Qiang; Liu, Guang-Ming; Long, Chun-Lin; Wang, Yue-Hu; Cheng, Yong-Xian. (2009). Hastatusides A and B: Two New Phenolic Glucosides from Rumex hastatus. Helvetica Chimica Acta 92(4): 774-778.

11111Zhang, Qiang; Di, Ying-Tong; Li, Chun-Shun; Fang, Xin; Tan, Cheng-Jian; Zhang, Zhen; Zhang, Yu; He, Hong-Ping; Li, Shun-Lin; Hao, Xiao-Jiang. (2009). Daphenylline, a New Alkaloid with an Unusual Skeleton, from Daphniphyllum longeracemosum. Organic Letters 11(11): 2357-2359.

11111Zhang, Quan; Jiang, Zhi-Yong; Luo, Jie; Liu, Ji-Feng; Ma, Yun-Bao; Guo, Rui-Hua; Zhang, Xue-Mei; Zhou, Jun; Chen, Ji-Jun. (2009). Anti-HBV agents. Part 2: Synthesis and in vitro anti-hepatitis B virus activities of alisol A derivatives. Bioorganic & Medicinal Chemistry Letters 19(8): 2148-2153.

11111Zhang, Quan; Jiang, Zhi-Yong; Luo, Jie; Ma, Yun-Bao; Liu, Ji-Feng; Guo, Rui-Hua; Zhang, Xue-Mei; Zhou, Jun; Niu, Wei; Du, Fei-Fei; Li, Li; Li, Chuan; Chen, Ji-Jun. (2009). Anti-HBV agents. Part 3: Preliminary structure-activity relationships of tetra-acylalisol A derivatives as potent hepatitis B virus inhibitors. Bioorganic & Medicinal Chemistry Letters 19(23): 6659-6665.

11111Zhang, Rong-Ting; Feng, Tao; Cai, Xiang-Hai; Luo, Xiao-Dong. (2009). Two New Clerodane-type Diterpenoids from Gomphostemma microdon. Zeitschrift Fur Naturforschung Section B-a Journal of Chemical Sciences 64(4): 443-446.

11111Zhang, Xue-Mei; Gao, Lian-Ming; Moeller, Michael; Li, De-Zhu. (2009). Molecular evidence for fragmentation among populations of Taxus wallichiana var. mairei, a highly endangered in China. Canadian Journal of Forest Research-Revue Canadienne De Recherche Forestiere 39(4): 755-764.

11111Zhang, Yu; Di, Ying-Tong; Mu, Shu-Zhen; Li, Chun-Shun; Zhang, Qiang; Tan, Cheng-Jian; Zhang, Zhen; Fang, Xin; Hao, Xiao-Jiang. (2009). Dapholdhamines A-D, Alkaloids from Daphniphyllum oldhami. Journal of Natural Products 72(7): 1325-1327.

11111Zhang, Yu; Di, Ying-Tong; Zhang, Qiang; Mu, Shu-Zhen; Tan, Cheng-Jian; Fang, Xin; He, Hong-Ping; Li, Shun-Lin; Hao, Xiao-Jiang. (2009). Daphhimalenine A, a New Alkaloid with an Unprecedented Skeleton, from Daphniphyllum himalense. Organic Letters 11(23): 5414-5417.

11111Zhang, Yu-Mei; Tan, Ning-Hua; Zeng, Guang-Zhi; Adebayo, Abiodun Humphrey; Ji, Chang-Jiu. (2009). A new norlignan from ascendens. Fitoterapia 80(6): 361-363.

11111Zhang, Zhen; Di, Ying-Tong; Wang, Yue-Hu; Zhang, Zhen; Mu, Shu-Zhen; Fang, Xin; Zhang, Yu; Tan, Cheng-Jian; Zhang, Qiang; Yan, Xiao-Hui; Guo, Jie; Li, Chun-Shun; Hao, Xiao-Jiang. (2009). Gelegamines A-E: five new oxindole alkaloids from Gelsemium elegans. Tetrahedron 65(23): 4551-4556.

75 11111Zhao, Pei-Ji; Gao, Suo; Fan, Li-Ming; Nie, Jing-Lei; He, Hong-Ping; Zeng, Ying; Shen, Yue-Mao; Hao, Xiao- Jiang. (2009). Approach to the Biosynthesis of Atisine-Type Diterpenoid Alkaloids. Journal of Natural Products 72(4): 645-649.

11111Zhao, Xu; Zheng, Guo-Wei; Niu, Xue-Mei; Li, Wei-Qi; Wang, Fu-Sheng; Li, Sheng-Hong. (2009). Terpenes from Eupatorium adenophorum and Their Allelopathic Effects on Arabidopsis Seeds Germination. Journal of Agricultural and Food Chemistry 57(2): 478-482.

11111Zhao, Xing-Feng; Sun, Wei-Bang. (2009). Abnormalities in sexual development and pollinator limitation in Michelia coriacea (Magnoliaceae), a critically endangered endemic to Southeast Yunnan, China. Flora 204(6): 463-470.

11111Zhao, Xing-Feng; Sun, Wei-Bang; Yang, Jun-Bo; Meng, Jing. (2009). Isolation and characterization of 12 microsatellite loci for Michelia coriacea (Magnoliaceae), a critically endangered endemic to Southeast Yunnan, China. Conservation Genetics 10(5): 1583-1585.

11111Zhao, Yong; Huang, Sheng-Xiong; Xiao, Wei-Lie; Ding, Li-Sheng; Pu, Jian-Xin; Li, Xian; Yang, Li-Bin; Sun, Han-Dong. (2009). Diterpenoids from Isodon pharicus. Tetrahedron Letters 50(17): 2019-2023.

11111Zhao, Yong; Huang, Sheng-Xiong; Yang, Li-Bin; Pu, Jian-Xin; Xiao, Wei-Lie; Li, Li-Mei; Lei, Chun; Weng, Zhi-Ying; Han, Quan-Bin; Sun, Han-Dong. (2009). Cytotoxic ent-Kaurane Diterpenoids from Isodon henryi. Planta Medica 75(1): 65-69.

11111Zhao, Yong; Pu, Jian-Xin; Huang, Sheng-Xiong; Ding, Li-Sheng; Wu, Ying-Li; Li, Xian; Yang, Li-Bin; Xiao, Wei-Lie; Chen, Guo-Qiang; Sun, Han-Dong. (2009). ent-Kaurane Diterpenoids from Isodon pharicus. Journal of Natural Products 72(6): 988-993.

11111Zhao, Yong; Pu, Jian-Xin; Huang, Sheng-Xiong; Wu, Ying-Li; Yang, Li-Bin; Xiao, Wei-Lie; Han, Quan-Bin; Chen, Guo-Qiang; Sun, Han-Dong. (2009). ent-Kaurane Diterpenoids from Isodon scoparius. Journal of Natural Products 72(1): 125-129.

11111Zheng, Y. L.; Sun, W. B.; Zhou, Y.; Coombs, D. (2009). Variation in seed and seedling traits among natural populations of Trigonobalanus doichangensis (A. Camus) Forman (), a rare and endangered plant in southwest China. New Forests 37(3): 285-294.

11111Zheng, Y. L.; Sun, W.B. (2009). Seed germination of Huagaimu, a critically endangered plant endemic to Southeast Yunnan, China. HortTechnology 19(2): 427-431.

11111Zhou, Jun. (2009). New Understanding of the Basic Theory of Traditional Chinese Medicine. Chinese Journal of Integrative Medicine 15(1): 7-12.

11111Zhou, Jing; Gong, Xun; Downie, Stephen R.; Peng, Hua. (2009). Towards a more robust molecular phylogeny of Chinese Apiaceae subfamily Apioideae: Additional evidence from nrDNA ITS and cpDNA intron (rpl16 and rps16) sequences. and Evolution 53(1): 56-68.

76 11111Zhou, Zhong-Yu; Liu, Rong; Jiang, Meng-Yuan; Zhang, Ling; Niu, Yun; Zhu, Ying-Cheng; Dong, Ze-Jun; Liu, Ji-Kai. (2009). Two New Cleistanthane Diterpenes and a New Isocoumarine from Cultures of the Basidiomycete Albatrellus confluens. Chemical & Pharmaceutical Bulletin 57(9): 975-978.

11111Zhu, Hua-Jie; Ren, Jie; Pittman, Charles U. Jr. (2009). Matrix model to predict specific optical rotations of acyclic chiral molecules (vol 63, pg 2292, 2007). Tetrahedron 65(12): 2610-2612.

11111Zuo, Guo-Ying; He, Hong-Ping; Shen, Yue-Mao; Xu, Xiao-Jie; Wang, Zhe-Ming; Yan, Chun-Hua; Hao, Xiao- Jiang. (2009). Spiraeosides A and B, Two New Diterpenoid Glucosides from Spiraea japonica var. ovalifolia. Planta Medica 75 (12): 1349-1351

Other Publications

111 Aquila, Silvia; Weng, Zhi-Ying; Zeng, Yue-Qin; Sun, Han-Dong; Ríos, José-Luis. (2009). Inhibition of NF- κB Activation and iNOS Induction by ent-Kaurane Diterpenoids in LPS-Stimulated RAW264.7 Murine Macrophages. Journal of Natural Products 72: 1269-1272

222 Bush, Catherine M.; Lu, Lu; Fritsch, Peter W.; Li, De-Zhu; Kron, Kathleen A. (2009). Phylogeny of Gaultherieae (Ericaceae: Vaccinioideae) Based on DNA Sequence data from matK, ndhF, AND nrITS. International Journal of Plant Sciences 170(3): 355-364.

333 Cheng, Pi; Chen, Ji-Jun; Huang, Ning; Wang, Rui-Rui; Zheng, Yong-Tang; Liang, Yi-Zeng. (2009). Synthesis and Anti-Human Immunodeficiency Virus Type 1 Activity of (E)-N-Phenylstyryl-N-alkylacetamide Derivatives. Molecules 14(9): 3176-3186.

444 Dai, Yu-Cheng; Yang, Zhu-Liang; Cui, Bao-Kai; Yu, Chang-Jun; Zhou, Li-Wei. (2009). Species Diversity and Utilization of Medicinal Mushrooms and Fungi in China (Review). International Journal of Medicinal Mushrooms 11(3): 287-302.

555 Deng, Yun-Fei; Wu, Zheng-Yi. (2009). A New Combination in Mackaya (Acanthaceae), with Lectotypification for Mackaya tapingensis. Novon 19(3): 307-309.

666 Dillon, Michael O.; Tu, Tie-Yao; Xie, Lei; Quipuscoa, Silvestre Victor; Wen, Jun; Sp. Iss. SI. (2009). Biogeographic diversification in Nolana (Solanaceae), a ubiquitous member of the Atacama and Peruvian Deserts along the western coast of South America. Journal of Systematics and Evolution 47(5): 457-476.

777 Ding, Qiang; Yang, Li-Xin; Yang, Hai-Wei; Jiang, Chao; Wang, Yi-Fen; Wang, Shui. (2009). Cytotoxic and antibacterial triterpenoids derivatives from Clematis ganpiniana. Journal of Ethnopharmacology 126(3): 382-385.

888 Duan, Lin; Tao, Hong-Wen; Hao, Xiao-Jiang; Gu, Qian-Qun; Zhu, Wei-Ming. (2009). Cytotoxic and Antioxidative Phenolic Compounds from the Traditional Chinese Medicinal Plant, Myristica fragrans. Planta Medica 75(11): 1241-1245.

77 999 Esposito, Karin; Reierson, G illian W; Luo, Huai-Rong; Wu, Gui-Sheng; Licinio, Julio; Wong, Ma-Li. (2009). Association of PDE11A global haplotype with major depression and antidepressant drug response. Neuropsychiatric Disease and Treatment 5:163-170

1111 Fan, Jie; Qin, Hai-Ning; Li, De-Zhu; Jin, Xiao-Hua. (2009). Molecular phylogeny and biogeography of Holcoglossum (Orchidaceae: Aeridinae) based on nuclear ITS, and chloroplast trnL-F and matK. Taxon 58(3): 849-861.

1111 Gan, Yu-Juan; Mei, Wen-Li; Zhao, You-Xing; Dai, Hao-Fu. (2009). A new cytotoxic cardenolide from the latex of Antiaris toxicaria. Chinese Chemical Letters 20(4): 450-452.

1111 Gao, Tian-Gang; Wang, Wei; Bayer, Randall J.; Li, De-Zhu. (2009). Systematic position of the enigmatic genus Sheareria (Asteraceae)-evidence from molecular, morphological and cytological data. Taxon 58(3): 769-780.

1111 Grumbine, R. Edward; Xu, Jian-Chu. (2009). China Shakes the World-and Then What? Conservation Biology 23(3): 513-515.

1111 Guo, Shuang-Xing; Sha, Jin-Geng; Bian, Li-Zeng; Qiu, Yin-Long. (2009). Male spike strobiles with Gnetum affinity from the Early Cretaceous in western , . Journal of Systematics and Evolution 47(2): 93-102.

1111 Han, Q.-B.; Xu, H.-X. (2009). Caged Garcinia Xanthones: Development Since 1937. Current Medicinal Chemistry 16(28): 3775-3796.

1111 Han, Zhuang; Mei, Wen-Li; Zhao, You-Xing; Deng, Yuan-Yuan; Dai, Hao-Fu. (2009). A New Cytotoxic Isocoumarin from Endophytic Fungus Penicillium SP 091402 of the Mangrove Plant Bruguiera sexangula. Chemistry of Natural Compounds 45(6): 805-807.

1111 Jang, Dae-Sik; Lee, Ga-Young; Lee, Yun-Mi; Kim, Young-Sook; Sun, Hang; Kim, Dong-Hee; Kim, Jin-Sook. (2009). Flavan-3-ols having a gamma-Lactam from the Roots of Actinidia arguta Inhibit the Formation of Advanced Glycation End Products in Vitro. Chemical & Pharmaceutical Bulletin 57(4): 397-400.

1111 Jia, Ai-Qun; Tan, Ning-Hua; Zhou, Jun. (2009). Two new minor cyclopeptides from Sagina japonica (Caryophyllaceae). Fitoterapia 80(3): 192-195.

1111 Kim, Sang-Yong; Kashiwada, Yoshiki; Kawazoe, Kazuyoshi; Murakami, Kotaro; Sun, Han-Dong; Li, Shun- Lin; Takaishi, Yoshihisa. (2009). Spicachlorantins A and B, new dimeric sesquiterpenes from the roots of Chloranthus spicatus. Phytochemistry Letters 2(3): 110-113.

2222 Kim, Sang-Yong; Kashiwada, Yoshiki; Kawazoe, Kazuyoshi; Murakami, Kotaro; Sun, Han-Dong; Li, Shun- Lin; Takaishi, Yoshihisa. (2009). Spicachlorantins C-F, hydroperoxy dimeric sesquiterpenes from the roots of Chloranthus spicatus. Tetrahedron Letters 50(44): 6032-6035.

78 2222 Kim, Woncheol; Lee, Dongho; Hong, Seong-Su; Na, Zhu; Shin, Jin-Chul; Roh, Su-Heun; Wu, Cheng-Zhu; Choi, Oksik; Lee, Kyeong; Shen, Yue-Mao; Paik, Sang-Gi; Lee, Jung-Joon; Hong, Young-Soo. (2009). Rational Biosynthetic Engineering for Optimization of Geldanamycin Analogues. Chembiochem 10(7): 1243-1251.

2222 Li, Rong; Hu, Chi-Ming. (2009). lihengiana (Primulaceae), a new species from Yunnan, China. Annales Botanici Fennici 46(2): 130-132.

2222 Li, Su-Mei; Yang, Xian-Wen; Li, Yong-Li; Shen, Yun-Heng; Feng, Lin; Wang, Yue-Hu; Zeng, Hua-Wu; Liu, Xiao-Hua; Zhang, Chang-Sheng; Long, Chun-Lin; Zhang, Wei-Dong. (2009). Chemical Constituents of Dracocephalum forrestii. Planta Medica 75(15): 1591-1596.

2222 Li, Ying-Ke; Zhao, Qing-Jie; Hu, Jiang; Zou, Zui; He, Xing-Ying; Yuan, Hong-Bin; Shi, Xue-Yin. (2009). Two New Quinoline Alkaloid Mannopyranosides from . Helvetica Chimica Acta 92(5): 928-931.

2222 Liang, Guang-Yi; Xu, Bi-Xue; Pan, Wei-Dong; Cao, Pei-Xue; Zhang, Yong; Lu, Yang; Wu, Yun-Shan; Hao, Xiao-Jiang. (2009). A novel iridoid from Torricellia angulata var intermedia. Natural Product Research 23(1): 1-4.

2222 Liao, Pei-Chun; Gong, Xun; Shih, Huei-Chuan; Chiang, Yu-Chung. (2009). Isolation and characterization of eleven polymorphic microsatellite loci from an endemic species, polysyphonum (Piperaceae). Conservation Genetics 10(6): 1911-1914.

2222 Liu, Xian-Wei; Xia, Cheng-Feng; Li, Lei; Guan, Wan-Yi; Pettit, Nicholas; Zhang, Hou-Cheng; Chen, Min; Wang, Peng-George. (2009). Characterization and synthetic application of a novel beta 1,3-galactosyltransferase from Escherichia coli O55:H7. Bioorganic & Medicinal Chemistry 17(14): 4910-4915.

2222 Luo, Du-Qiang; Zhao, Li-Yan; Shi, Yao-Long; Tang, Hong-Liang; Li, Yu-Ye; Yang, Liu-Meng; Zheng, Yong-Tang; Zhu, Hua-Jie; Liu, Ji-Kai. (2009). Velleratretraol, an unusual highly functionalized lactarane sesquiterpene from Lactarius vellereus. Journal of Antibiotics 62(3): 129-132.

2222 Ma, Wen-Zhang; Liu, Wen-Yao; Li, Xing-Jiang. (2009). Species composition and life forms of epiphytic in old-growth and secondary forests in Mt. Ailao, SW China. Cryptogamie Bryologie 30(4): 477-500.

3333 Mao, Wei; Yang, Han-Qi; Li, De-Zhu. (2009). xishuangbannaensis (: Bambusoideae), a new species from Yunnan, China. Annales Botanici Fennici 46(6): 574-576.

3333 Nagano, Hajime; Torihata, Atsushi; Matsushima, Mika; Hanai, Ryo; Saito, Yoshinori; Baba, Makiko; Tanio, Yui; Okamoto, Yasuko; Takashima, Yuriko; Ichihara, Mayu; Gong, Xun; Kuroda, Chiaki; Tori, Motoo. (2009). Chemical and Genetic Study of Ligularia cyathiceps in Yunnan Province of China. Helvetica Chimica Acta 92(10): 2071-2081. 3333 Nakano, Masaru; Takagi, Hiroki; Sugawara, Shintaro; Saito, Tomoka; Watanabe, Yusuke; Lu, Yuan-Xue; Guan, Kai-Yun; Godo, Toshinari. (2009). Adventitious Shoot Regeneration and Micropropagation of Chirita flavimaculata W. T. Wang, C. Eburnea Hance, and C. Speciosa Kurz. Propagation of Ornamental Plants 9(4): 216-222.

79 3333 Nimgirawath, Surachai; Lorpitthaya, Rujee; Wanbanjob, Asawin; Taechowisan, Thongchai; Shen, Yue-Mao. (2009). Total Synthesis and the Biological Activities of (+/-)-Norannuradhapurine. Molecules 14(1): 89-101.

3333 Nimgirawath, Surachai; Udomputtimekakul, Phansuang; Taechowisan, Thongchai; Wanbanjob, Asawin; Shen, Yue-Mao. (2009). First Total Syntheses of (+/-)-Isopiline, (+/-)-Preocoteine, (+/-)-Oureguattidine and (+/-)-3-Methoxynordomesticine and the Biological Activities of (+/-)-3-Methoxynordomesticine. Chemical & Pharmaceutical Bulletin 57(4): 368-376.

3333 Pi, Hui-Fang; Zhang, Peng; Ruan, Han-Li; Zhang, Yong-Hui; Sun, Han-Dong; Wu, Ji-Zhou. (2009). A new alkaloid from Lycoris aurea. Chinese Chemical Letters 20(11): 1319-1320

3333 Pi, Hui-Fang; Zhang, Peng; Ruan, Han-Li; Zhang, Yong-Hui; Sun, Han-Dong; Wu, Ji-Zhou. (2009). Two new triterpenoids from the leaves and stems of hupehensis. Journal of Asian Natural Products Research 20(11): 1319-1320

3333 Ren, Qiang; Sun, Zhong-Shuai; Wang, Li-Song; Zhao, Zun-Tian. (2009). A new species of Pertusaria (Pertusariaceae) from China. Mycotaxon 108: 231-234.

3333 Ren, Zhu-Mei; Zhu, Bin; Ma, Enbo; Wen, Jun; Tu, Tie-Yao; Cao, Ying; Hasegawa, Masami; Zhong, Yang. (2009). Complete nucleotide sequence and gene arrangement of the mitochondrial genome of the crab- eating frog Fejervarya cancrivora and evolutionary implications. Gene 441(1-2): 148-155.

3333 Sun, Wei-Hao; Chen, Guo-Sheng; Ou, Xi-Long; Yang, Ye; Luo, Cheng; Zhang, Yuan; Shao, Yun; Xu, Hai- Chen; Xiao, Bin; Xue, Yi-Ping; Zhou, Su-Ming; Zhao, Qin-Shi; Ding, Guo-Xian. (2009). Inhibition of COX-2 and activation of peroxisome proliferator-activated receptor gamma synergistically inhibits proliferation and induces apoptosis of human pancreatic carcinoma cells. Cancer Letters 275(2): 247-255.

4444 Tanaka, Hitoshi; Yatsuhashi, Saya; Yasuda, Tadashi; Sato, Masaru; Sakai, Eiji; Xiao, Chen; Murata, Hiroko; Murata, Jin. (2009). A new amide from the leaves and twigs of Litsea auriculata. Journal of Natural Medicines 63(3): 331-334.

4444 Torihata, Atsushi; Chao, Xun; Kuroda, Chiaki; Hanai, Ryo; Hirota, Hiroshi; Gong, Xun. (2009). Chemical and Genetic Differentiation of Ligularia hodgsonii in Japan and China. Chemistry & Biodiversity 6(12): 2184-2191.

4444 Wang, Conan-K.; Hu, Shu-Hong; Martin, Jennifer L.; Sjogren, Tove; Hajdu, Janos; Bohlin, Lars; Claeson, Per; Goransson, Ulf; Rosengren, K. Johan; Tang, Jun; Tan, Ning-Hua; Craik, David J. (2009). Combined X-ray and NMR Analysis of the Stability of the Cyclotide Cystine Knot Fold That Underpins Its Insecticidal Activity and Potential Use as a Drug Scaffold. Journal of Biological Chemistry 284(16): 10672-10683.

4444 Wang, Gang; Liu, Jin-Song; Lin, Bin-Bin; Wang, Guo-Kai; Liu, Ji-Kai. (2009). Two New Furanoid Norditerpenes from Dioscorea bulbifera. Chemical & Pharmaceutical Bulletin 57(6): 625-627.

4444 Wang, Hong; Wortley, Alexandra H.; Blackmore, Stephen. (2009). Pollen morphology of Crepidinae and Lactucinae (Asteraceae: Cichorieae) and its systematic significance. Grana 48(3): 160-178.

80 4444 Wang, Huan; Yu, Kai-Bei; Ding, Li-Sheng; Luo, Xiao-Duo; Zhang, Xiao-Feng. (2009). 3 alpha-Hydroxy-ent- atis-16-en-14-one. Acta Crystallographica Section E-Structure Reports Online 65: O1832-U2755.

4444 Wang, H.; Yu, W. B.; Chen, J. Q.; Blackmore, S. (2009). Pollen morphology in relation to floral types and pollination syndromes in Pedicularis (Orobanchaceae). Plant Systematics and Evolution 277(3-4): 153-162.

4444 Wang, Q. Z.; Wang, M. F.; Ma, J. R.; Li, Z. X.; Zhang, G. M.; Liu, X. M.; Xue, C. Y. (2009). Allele-specific primers for diagnostic PCR authentication of Halenia elliptica, a traditional Tibetan medicinal plant. Planta Medica 75(9): 898-898.

4444 Wang, Xiao-Yu; Sun, Lian-Li; Huang, Ke-Xin; Shi, Shu-Yun; Zhang, Li-Juan; Xu, Juan-Hua; Peng, Hua; Sun, Xian-Feng; Wang, Li-Wei; Wu, Xiu-Mei; Zhao, Yu; Li, Xiao-Kun; Stockigt, Joachim; Qu, Jia. (2009). Phytochemical Investigation and Cytotoxic Evaluation of the Components of the Medicinal Plant Ligularia atroviolacea. Chemistry & Biodiversity 6(7): 1053-1065.

4444 Wu, Hai-Feng; Ding, Li-Sheng; Shen, Jian-Wei; Zhu, Hua-Jie; Zhang, Xiao-Feng. (2009). A new proaporphine alkaloid from Meconopsis horridula. Fitoterapia 80(4): 252-254.

5555 Wu, Shao-Hua; Shen, Yue-Mao; Chen, You-Wei; Li, Zhi-Ying; Yang, Li-Yuan; Li, Shao-Lan. (2009). Chemical constituents from the stem bark of Trewia nudiflora. Chemistry of Natural Compounds 45(4): 536-538.

5555 Wang, Ya-Feng; Wang, Xiao-Yan; Ren, Zhe; Qian, Chui-Wen; Li, Yi-Cheng; Kaio, Kitazato; Wang, Qing- Duan; Zhang, Yan; Zheng, Li-Yun; Jiang, Jin-Hua; Yang, Chong-Ren; Liu, Qing; Zhang, Ying-Jun; Wang, Yi-Fei. (2009). Phyllaemblicin B inhibits Coxsackie virus B3 induced apoptosis and myocarditis. Antiviral Research 84(2): 150-158.

5555 Yang, Wen-Jing; Li, Liang-Qian; Xie, Lei. (2009). A revision of Clematis sect. Atragene (Ranunculaceae). Journal of Systematics and Evolution 47(6): 552-580.

5555 Yang, Yun-Shan; Sun, Han-Dong; Zhou, Yi-Ping; Ji, Shu-Yu; Li, Ma-Lin. (2009). Effects of three diterpenoids on tumour cell proliferation and telomerase activity. Natural Product Research 23(11): 1007-1012.

5555 Ye, Guan; Li, Zhi-Xiong; Xia, Guang-Xin; Peng, Hua; Sun, Zhao-Lin; Huang, Cheng-Gang. (2009). A New Iridoid Alkaloid from the Flowers of Plumeria rubra L. cv. acutifolia. Helvetica Chimica Acta 92(12): 2790-2794.

5555 Yi, San-San; Akashi, Yukari; Tanaka, Katsunori; Cho, Tin-Tin; Khaing, May-Thin; Yoshino, Hiromichi; Nishida, Hidetaka; Yamamoto, Tatsuya; Win, Kyaw; Kato, Kenji. (2009). Molecular analysis of genetic diversity in melon landraces (Cucumis melo L.) from Myanmar and their relationship with melon germplasm from East and South Asia. Genetic Resources and Crop Evolution 56(8): 1149-1161.

5555 Zhang, Ji-Xia; He, Zhi-An; Chen, Zheng-Yue; Wang, Yong-Xue; Bai, Su-Ping; Sun, Han-Dong. (2009). Cytotoxic ent-kaurane diterpenoids from Isodon macrophyllus. Journal of Asian Natural Products Research 11(8): 693-697.

81 5555 Zhang, Ji-Xia; Wang, Yong-Xue; He, Zhi-An; Yan, Fu-Lin; Sun, Han-Dong. (2009). Two new ent-kaurane diterpenoids from Isodon excisoides. Chinese Chemical Letters 20(2): 201-203.

5555 Zhang, Li; Fang, Xin; Hao, Xiao-Jiang; Lu, Yang. (2009). 2a, 3a-Dihydroxyandrostan-16-one. Acta Crystallographica Section E-Structure Reports Online 65: O2043-U4562.

5555 Zheng, Jin-Kai; Zhu, Hua-Jie; Hong, Kui; Wang, Yi; Liu, Pei-Pei; Wang, Xin; Peng, Xiao-Ping; Zhu, Wei- Ming. (2009). Novel Cyclic Hexapeptides from Marine-Derived Fungus, Aspergillus sclerotiorum PT06-1. Organic Letters 11(22): 5262-5265.

6666 Zhou, Xiao-Jian; Zhang, Zhen; Xu, Ying; Jin, Cui-Li; He, Hong-Ping; Hao, Xiao-Jiang; Qian, Pei-Yuan. (2009). Flavone and isoflavone derivatives of terrestrial plants as larval settlement inhibitors of the barnacle Balanus amphitrite. Biofouling 25(1): 69-76.

6666 Zhou, Yan; Xu, Gang; Choi, Franky Fung Kei; Ding, Li-Sheng; Bin, Han-Quan; Song, Jing-Zheng; Qiao, Chun-Feng; Zhao, Qin-Shi; Xu, Hong-Xi. (2009). Qualitative and quantitative analysis of diterpenoids in Salvia species by liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry. Journal of Chromatography A 1216(24): 4847-4858.

6666 Zhou, Yan; Yang, Bin-Li; Yang, Jing; Huang, Sheng-Xiong; Sun, Han-Dong; Xu, Hong-Xi; Ding, Li-Sheng. (2009). Electrospray ionization tandem mass spectrometric analysis of ent-6, 7-seco-kaurane diterpenoids from the Isodon species. Rapid Communications in Mass Spectrometry 23(1): 138-146.

6666 Zhu, Judy T. T.; Choi, Roy C. Y.; Li, Jun; Xie, Heidi Q. H.; Bi, Cathy W. C.; Cheung, Anna W. H.; Dong, Tina T. X.; Jiang, Zhi Y.; Chen, Ji J.; Tsim, Karl W. K. (2009). Estrogenic and Neuroprotective Properties of Scutellarin from Erigeron breviscapus: A Drug against Postmenopausal Symptoms and Alzheimer's Disease. Planta Medica 75(14): 1489-1493. 6666 Zhu, Judy T. T.; Choi, Roy C. Y.; Xie, Heidi Q.; Zheng, Ken Y. Z.; Guo, Ava J. Y.; Bi, Cathy W. C.; Lau, David T. W.; Li, Jun; Dong, Tina T. X.; Lau, Brad W. C.; Chen, Ji J.; Tsim, Karl W. K. (2009). Hibifolin, a flavonol glycoside, prevents beta-amyloid-induced neurotoxicity in cultured cortical neurons. Neuroscience Letters 461(2): 172-176.

6666 Ziegler, Alan D.; Fox, Jefferson M.; Xu, Jian-Chu. (2009). The Rubber Juggernaut. Science 324(5930): 1024-1025.

82 APPENDIX 3 LIST OF PATENTS GRANTED AND APPLIED

List of patents Granted 2009

Application Issue Date Name of Patents Inventors Patent No. Date of patent

Pinus Khasya Chemical Increasing QIU Ming-Hua LI Zhong- Oleoresin Agent and its Method of Rong LUO Ting-Xiang YAN ZL200610011093.3 2006.08.02 2009.02.11 Preparation Jian ZHOU Lin

HAO Xiao-Jiang FANG Anti-viral Agent, its Method of Rong-Xiang LI Yan-Mei ZL200510010936.3 2005.07.26 2009.03.18 Preparation and Application CHEN Xiao-Ying LI Shun- Lin

Helicid- Huperzine A Acetal Imine, QIU Ming-Hua YAN Jian its Method of Preparation and YANG Fu-Mei YANG Xiao- ZL200710065827.0 2007.04.20 2009.06.24 Application Sheng ZHOU Lin YI Ping

Method for Preparation of Ursolic LUO Xiao-Dong CAI Xiang- ZL200610048656.6 2006.09.05 2009.08.12 Acid Hai

Method for Preparation of Plant WANG Hao-Xin ZENG Ying ZL200710065724.4 2007.03.19 2009.08.19 Endophyte SHEN Yue-Mao

HAO Xiao-Jiang LI Yan- Chemical Activator, its Method of Mei CHEN Gang LUO Xiao- ZL200710065721.0 2007.03.19 2009.08.19 Preparation and Application Dong ZHANG Zhong-Kai HE Hong-Ping

QIU Ming-Hua YAN Jian Huperzine A Derivative, its Method YANG Fu-Mei YI Ping ZHOU ZL200710065824.7 2007.04.20 2009.08.1 of Preparation and Application Lin YANG Xiao-Sheng

CHEN Ji-Jun WU Ying-Rui ZHAO You-Xing MA Yun- Medicine for Curing Hepatitis B ZL200710065709.X 2007.03.13 2009.09.30 Bao YAO Shu-Ying ZHOU Jun

CHEN Ji-Jun JIANG Zhi- Medical Composition for Curing Yong ZHANG Feng-Xue LIU ZL200510010827.1 2005.05.27 2009.09.3 Hepatitis B Ni ZHAO Fang ZHANG Xue- Mei ZHOU Jun

83 List of Patents Applied 2009

Application Invention Names Applicant (s) Inventors Application No. Date

Kunming Institute of Tea, Preparation Method ZHANG Ying-Jun LIU Qing Botany, Chinese Academy 2009.01.12 200910094036.X and Application XU Min YANG Chong-Ren of Sciences

Kunming Institute of HE Shu-Zhen CHEN Ypsilandra Tissue Culture Botany, Chinese Academy Chang-Xiang LIU Hai- 2009.01.23 200910094057.1 and Plant Method of Sciences Yang NI Wei

Hyaluronidase Inhibitor, Kunming Institute of ZHANG Ying-Jun LIU Preparation Method and Botany, Chinese Academy Qing QIAO Chun-Ling XU 2009.01.23 200910094058.6 Application of Sciences Min YANG Chong-Ren

Kunming Institute of LI Xiao-Li YANG Yong- Antineoplastic Drugs Botany, Chinese Academy Ping LI Yang HAN Li-Wen Composition and of Sciences and Biology 2009.01.23 200910094056.7 WANG Si-Feng LIU Ke- Application Institute of Shandong Chun Academy of Sciences

Kunming Institute of ZHOU Jun ZHAO You- Method for propagating Botany, Chinese Academy Xing LIU Yu-Qing CAO and planting seeds of of Sciences and Kunming 2009.04.03 200910094291.4 Jia-Ju ZHAO Jian-Guo XU Valerianae Dihon Pharmaceutical Yun-Feng Co.,Ltd

Kunming Institute of ZHOU Jun ZHAO You- Method for propagating Botany, Chinese Academy Xing LIU Yu-Qing CAO and planting Tissues of of Sciences and Kunming 2009.04.03 200910094291.4 Jia-Ju ZHAO Jian-Guo XU Valerianae Dihon Pharmaceutical Yun-Feng Co.,Ltd

Medlar nutrient Kunming Institute of CHENG Yong-Xian DONG substance, Preparation Botany, Chinese Academy Sha-Sha LV Qing HUANG 2009.05.15 200910094462.3 Method and Application of Sciences Zhao-Xiong

84 Wallnut nutrient Kunming Institute of CHENG Yong-Xian LV substance, soft capsule Botany, Chinese Academy 2009.05.15 200910094463.8 Qing BU Wei and healthy product of Sciences

Cycloartane Triterpenoid QIU Ming-Hua NIAN Yin Alkyl Type Compound, Kunming Institute of ZHANG Yan-Li QING its Medical Composition, Botany, Chinese Academy 2009.06.05 200910094550.3 Chen ZHOU Lin CHEN Preparation Method and of Sciences Jian-Chao LI Zhong-Rong Application

Alismol A Derivative, CHEN Ji-Jun ZHANG Quan Kunming Institute of medical composition, JIANG Zhi-Yong LUO Jie Botany, Chinese Academy 2009.07.03 200910094689.8 preparation method and MA Yun-Bao ZHOU Jun of Sciences application ZHANG Xue-Mei

Method for Cultivating Kunming Institute of HUANG Jia-Lin CHENG and Rapid Propagating Botany, Chinese Academy Ai-Hua YAN Ning HU 2009.07.03 200910094690.0 Sophora flavescens of Sciences Hong KANG Zhi-Yu

Kunming Institute of Botany, Chinese Academy HE Jun ZHOU Zhi-Mei XU Artificial propagation and of Sciences and Forestry Jian-Chu YANG Hui-Xian conservation method of 2009.07.09 200910094701.5 Technique Extension LU Ding-Wei LI Hong-Wei Wild Thelephora bacteria General Station of SHANG Su-Qin Baoshan Kunming Institute of Botany, Chinese Academy HE Jun ZHOU Zhi-Mei XU Stereoscopic Plant of Sciences and Forestry Jian-Chu -Ping method on Cultivated 2009.7.09 200910094702.X Technique Extension YU Yong-Ming YIN Rui-Ze Land for Quitting General Station of QU Chun-Xia Baoshan

Method for cultivating Kunming Institute of YIN Qing SUN Wei-Bang and planting rare and Botany, Chinese Academy CHEN You-Sheng LUO 2009.07.09 200910094703.4 endangered plant seeds of Sciences Gui-Fen DAN Guo-Li of acer yangbiense

Method for Extracting Kunming Institute of LIU Xi-Kui XIAO Jian- total alkali, reserpine and Botany, Chinese Academy 2009.08.05 200910094803.7 Qing ZHANG Fang-Jin rutin from Rauwolfia of Sciences

Method for adjusting Kunming Institute of YAN Ning HU Hong PI flowering period of Botany, Chinese Academy 2009.08.05 200910094804.1 Qiu-Xia LI Shu-Yun armeniacum of Sciences

85 ZHU Hong-Tao ZHANG Method for Cultivating Kunming Institute of Ying-Jun XU Min WANG Gentiana rigescens tissue Botany, Chinese Academy 2009.09.18 200910094989.6 Ping YANG with Gentiopicrin of Sciences Chong-Ren

LIU Hai-Yang LI Ling Lindenrane dimeric Kunming Institute of CHEN Chang-Xiang SUN sesquiterpene Botany, Chinese Academy Ling TENG Fei HUANG 2009.10.13 200910095051.6 compound, preparation of Sciences and Kunming Nian-Xu RAN Xin-Hui NI method and application Medical College Wei HAO Xiao-Jiang GAO Suo

Cyclopentenyl Fatty Acid, Kunming Institute of CHENG Yong-Xian LV Preparation Method and Botany, Chinese Academy 2009.10.19 200910095064.3 Qing -Feng Application of Sciences

SUN Wei-Bang LI Cong- Method of Propagation Kunming Institute of Ren LUO Gui-Fen HAN and Cultivation of Botany, Chinese Academy 2009.10.29 200910095119.0 Chun-Yan JI Xu- Michelia‘Yuanzi’ of Sciences Yang

SUN Wei-Bang LI Cong- Method of Propagation Kunming Institute of Ren LUO Gui-Fen HAN and Cultivation of Botany, Chinese Academy 2009.10.29 200910095117.1 Chun-Yan JI Li FU Xu- Michelia ‘Duanzi’ of Sciences Yang

SUN Wei-Bang LI Cong- Method of Propagation Kunming Institute of Ren LUO Gui-Fen HAN and Cultivation of Botany, Chinese Academy 2009.10.29 200910095118.6 Chun-Yan JI Li FU Xu- Michelia ‘Yuxin’ of Sciences Yang

LUO Xiao-Dong FENG Tao Melonines Indole Kunming Institute of LI Yan WANG Yuan-Yuan Compound, Medical Botany, Chinese Academy 2009.11.04 200910095137.9 CAI Xiang-Hai LIU Ya- Composition and Usage of Sciences Ping

Kunming Institute of A Method for Preparing SUN Han-Dong HAN Botany, Chinese Academy 2009.11.12 200910095183.9 Eriocalyxin B Quan-Bin PU Jian-Xin of Sciences

Bithieny Compound, Kunming Institute of ZHU Hua-Jie LI Liang-Bo Medical Composition and Botany, Chinese Academy 2009.12.07 200910218293.X REN Jie Application of Sciences

86 Kunming Institute of Trigonostemon HAO Xiao-Jiang ZHENG Botany, Chinese Academy Lactones A-D, Medical Yong-Tang HE Hong-Ping of Science and Kunming Composition, Method HUANG Ning TAN Cheng- 2009.12.18 200910218391.03 Institute of Zoology, for Preparation and Jian LI Chun-Yan DI Ying- Chinese Academy of Application Tong WANG Rui-Rui Sciences

Trademark Registration 2009

Commodity Registered Registration Trade Name Valid Term Checked and Person Number Ratified

Kunming Institute From January 14, 2009 to HUA Fu-Le of Botany, Chinese No. 4811316 Class No. 5 January 13, 2019 Academy of Sciences

Kunming Institute From April 7, 2009 to April QI Shi-Le of Botany, Chinese No. 4798050 Class No. 5 6, 2019 Academy of Sciences

Application Items of New Cultivars of Plant 2009

Application Application Cultivar Name Applicant Breeders Date Number

Kunming Institute SUN Wei-Bang LI Cong-Ren Michelia ‘Yuxin of Botany, Chinese LUO Gui-Fen HAN Chun-Yan JI 2009.10.16 20090039 Academy of Science Li FU Xu-Yang

Kunming Institute SUN Wei-Bang LI Cong-Ren Michelia ‘Duanzi’ of Botany, Chinese LUO Gui-Fen HAN Chun-Yan JI 2009.10.16 20090040 Academy of Science Li FU Xu-Yang

Kunming Institute SUN Wei-Bang LI Cong-Ren Michelia ‘Yuanzi’ of Botany, Chinese LUO Gui-Fen HAN Chun-Yan JI 2009.10.16 20090041 Academy of Science Li FU Xu-Yang

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