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(12) Patent Application Publication (10) Pub. No.: US 2007/0143878 A1 Bhat Et Al US 20070143878A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2007/0143878 A1 Bhat et al. (43) Pub. Date: Jun. 21, 2007 (54) NUCLEC ACID MOLECULES AND OTHER of application No. 09/198.779, filed on Nov. 24, 1998, MOLECULES ASSOCATED WITH THE now abandoned. TOCOPHEROL PATHWAY Said application No. 09/233,218 is a continuation-in part of application No. 09/227,586, filed on Jan. 8, (76) Inventors: Barkur G. Bhat, St. Louis, MO (US); 1999, now abandoned. Sekhar S. Boddupalli, Manchester, MO Said application No. 09/233,218 is a continuation-in (US); Ganesh M. Kishore, Creve part of application No. 09/229,413, filed on Jan. 12, Coeur, MO (US); Jingdong Liu, 1999, now abandoned. Ballwin, MO (US); Shaukat H. Rangwala, Ballwin, MO (US); (60) Provisional application No. 60/067,000, filed on Nov. Mylavarapu Venkatramesh, Ballwin, 24, 1997. Provisional application No. 60/066,873, MO (US) filed on Nov. 25, 1997. Provisional application No. 60/069.472, filed on Dec. 9, 1997. Provisional appli Correspondence Address: cation No. 60/074,201, filed on Feb. 10, 1998. Pro ARNOLD & PORTER, LLP visional application No. 60/074.282, filed on Feb. 10, 555 TWELFTH STREET, N.W. 1998. Provisional application No. 60/074,280, filed ATTN IP DOCKETING on Feb. 10, 1998. Provisional application No. 60/074, WASHINGTON, DC 20004 (US) 281, filed on Feb. 10, 1998. Provisional application No. 60/074,566, filed on Feb. 12, 1998. Provisional (21) Appl. No.: 11/329,160 application No. 60/074,567, filed on Feb. 12, 1998. Provisional application No. 60/074.565, filed on Feb. (22) Filed: Jan. 11, 2006 12, 1998. Provisional application No. 60/074,789, filed on Feb. 19, 1998. Provisional application No. Related U.S. Application Data 60/075,459, filed on Feb. 19, 1998. Provisional appli (63) Continuation of application No. 09/267,199, filed on cation No. 60/075,460, filed on Feb. 19, 1998. Pro Mar. 12, 1999, now abandoned, which is a continu visional application No. 60/092,036, filed on Jul. 8, ation-in-part of application No. 09/198.779, filed on 1998. Provisional application No. 60/071,479, filed Nov. 24, 1998, now abandoned. on Jan. 13, 1998. Provisional application No. 60/085, Said application No. 09/267,199 is a continuation-in 533, filed on May 15, 1998. Provisional application part of application No. 09/229,413, filed on Jan. 12, 1999, now abandoned. (Continued) Said application No. 09/267,199 is a continuation-in part of application No. 09/252,974, filed on Feb. 19, Publication Classification 1999, now abandoned. Said application No. 09/267,199 is a continuation-in (51) Int. Cl. part of application No. 09/262,979, filed on Mar. 4, AOIH I/00 (2006.01) 1999, now abandoned. CI2O I/68 (2006.01) Said application No. 09/267,199 is a continuation-in C7H 2L/04 (2006.01) part of application No. 09/233,218, filed on Jan. 20. CI2N 9/10 (2006.01) 1999, now abandoned, which is a continuation-in-part C07K 6/40 (2006.01) of application No. 09/198.779, filed on Nov. 24, 1998, (52) U.S. Cl. .............................. 800/281; 435/6: 435/193; now abandoned. 536/23.2; 530/388.26 Said application No. 09/267,199 is a continuation-in part of application No. 09/233,218, filed on Jan. 20. 1999, now abandoned. (57) ABSTRACT Said application No. 09/267,199 is a continuation-in part of application No. 09/227,586, filed on Jan. 8, 1999, now abandoned. The present invention is in the field of plant biochemistry. Said application No. 09/233,218 is a continuation-in More specifically the invention relates to nucleic acid part of application No. 09/227,586, filed on Jan. 8, sequences from plant cells, in particular, nucleic acid 1999, now abandoned. sequences from maize and Soybean associated with the Said application No. 09/233,218 is a continuation-in tocopherol synthesis pathway enzymes. The invention part of application No. 09/229,413, filed on Jan. 12, encompasses nucleic acid molecules that encode proteins 1999, now abandoned. and fragments of proteins. In addition, the invention also Said application No. 09/267,199 is a continuation-in encompasses proteins and fragments of proteins so encoded part of application No. 09/237,183, filed on Jan. 26, and antibodies capable of binding these proteins or frag 1999, which is a continuation-in-part of application ments. The invention also relates to methods of using the No. 09/198,779, filed on Nov. 24, 1998, now aban nucleic acid molecules, proteins and fragments of proteins doned. and antibodies, for example for genome mapping, gene Said application No. 09/237,183 is a continuation-in identification and analysis, plant breeding, preparation of part of application No. 09/233,218, filed on Jan. 20. constructs for use in plant gene expression and transgenic 1999, now abandoned, which is a continuation-in-part plants. US 2007/0143878 A1 Page 2 Related U.S. Application Data 60/085.245, filed on May 13, 1998. Provisional appli cation No. 60/085,224, filed on May 13, 1998. Pro No. 60/089,806, filed on Jun. 18, 1998. Provisional visional application No. 60/085,223, filed on May 13, application No. 60/089,807, filed on Jun. 18, 1998. 1998. Provisional application No. 60/085,222, filed Provisional application No. 60/089,811, filed on Jun. on May 13, 1998. Provisional application No. 60/086, 18, 1998. Provisional application No. 60/089,808, 186, filed on May 21, 1998. Provisional application filed on Jun. 18, 1998. Provisional application No. No. 60/086,339, filed on May 21, 1998. Provisional 60/089,812, filed on Jun. 18, 1998. Provisional appli application No. 60/086,187, filed on May 21, 1998. cation No. 60/089,813, filed on Jun. 18, 1998. Pro Provisional application No. 60/086,185, filed on May visional application No. 607091,247, filed on Jun. 30. 21, 1998. Provisional application No. 60/086,184, 1998. Provisional application No. 60/091,405, filed filed on May 21, 1998. Provisional application No. on Jun. 30, 1998. Provisional application No. 60/099, 60/086,183, filed on May 21, 1998. Provisional appli 697, filed on Sep. 9, 1998. Provisional application cation No. 60/086,188, filed on May 21, 1998. Pro No. 60/100,963, filed on Sep. 17, 1998. Provisional visional application No. 60/089.524, filed on Jun. 16, application No. 60/101,343, filed on Sep. 22, 1998. 1998. Provisional application No. 60/089,810, filed Provisional application No. 60/101.344, filed on Sep. on Jun. 18, 1998. Provisional application No. 60/089, 22, 1998. Provisional application No. 60/101,347, 814, filed on Jun. 18, 1998. Provisional application filed on Sep. 22, 1998. Provisional application No. No. 607091,247, filed on Jun. 30, 1998. Provisional 60/101,508, filed on Sep. 22, 1998. Provisional appli application No. 60/092,036, filed on Jul. 8, 1998. cation No. 60/101,707, filed on Sep. 25, 1998. Pro Provisional application No. 60/099,667, filed on Sep. visional application No. 60/104,124, filed on Oct. 13, 9, 1998. Provisional application No. 60/099,668, filed 1998. Provisional application No. 60/104,126, filed on Sep. 9, 1998. Provisional application No. 60/099, on Oct. 13, 1998. Provisional application No. 60/104, 670, filed on Sep. 9, 1998. Provisional application 127, filed on Oct. 13, 1998. Provisional application No. 60/099,697, filed on Sep. 9, 1998. Provisional No. 60/104,128, filed on Oct. 13, 1998. Provisional application No. 60/100,674, filed on Sep. 16, 1998. application No. 60/111,981, filed on Dec. 11, 1998. Provisional application No. 60/100,673, filed on Sep. Provisional application No. 60/076,709, filed on Jun. 16, 1998. Provisional application No. 60/100,672, 9, 1998. Provisional application No. 60/084,.684, filed filed on Sep. 16, 1998. Provisional application No. on May 8, 1998. Provisional application No. 60/076, 60/101,132, filed on Sep. 21, 1998. Provisional appli 912, filed on Mar. 6, 1998. Provisional application cation No. 60/101,130, filed on Sep. 21, 1998. Pro No. 60/067,000, filed on Nov. 24, 1997. Provisional visional application No. 60/108,996, filed on Nov. 18, application No. 60/066,873, filed on Nov. 25, 1997. 1998. Provisional application No. 60/109,018, filed Provisional application No. 60/069.472, filed on Dec. on Nov. 19, 1998. Provisional application No. 60/071, 9, 1997. Provisional application No. 60/074,201, filed 064, filed on Jan. 9, 1998. Provisional application No. on Feb. 10, 1998. Provisional application No. 60/074, 60/090,170, filed on Jun. 22, 1998. Provisional appli 282, filed on Feb. 10, 1998. Provisional application cation No. 60/075,462, filed on Feb. 19, 1998. Pro No. 60/074,280, filed on Feb. 10, 1998. Provisional visional application No. 60/075,461, filed on Feb. 19, application No. 60/074.281, filed on Feb. 10, 1998. 1998. Provisional application No. 60/075,464, filed Provisional application No. 60/074,566, filed on Feb. on Feb. 19, 1998. Provisional application No. 60/075, 12, 1998. Provisional application No. 60/074,567, 460, filed on Feb. 19, 1998. Provisional application filed on Feb. 12, 1998. Provisional application No. No. 60/077,231, filed on Mar. 9, 1998. Provisional 60/074.565, filed on Feb. 12, 1998. Provisional appli application No. 60/077,229, filed on Mar. 9, 1998.
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