CBB FIRST EDITION | 2016 IMPACT REPORT THE CENTRE FOR BIOENGINEERING AND BIOTECHNOLOGY

Positioned at the cross-roads of physics, chemistry, biology, engineering and medicine, biotechnology and bioengineering hold dramatic promise for improving quality of human health, environment, and bio-industries. CBB DIRECTOR

welcome to the future

The Centre for Bioengineering and Biotechnology (CBB) provides interdisciplinary leadership in the fields of biotechnology and biomedical engineering.

CBB brings together faculty members from all and encourages students to become members of faculties on campus who have an interest in CBB. CBB also pursues strategic partnerships with exploring how human health can be improved international partners who can complement our work. through technology. The common thread among our researchers is a passion for understanding CBB hosts focus days with companies, networking how synergy of life science and engineering events, academic seminars, research translation can improve our lives and society. workshops and student events. We support researchers in grant applications and seek out new CBB is deliberately broad in its scope and in its opportunities for our members. Further, CBB’s rich mandate. CBB’s founding philosophy was grounded network enables us to connect our members with on a recognition that solutions to the toughest the right people internally and externally. problems involve the most innovative people and integration of a wide variety of perspectives. The next decade promises to be a revolutionary time One way to think out of the box is to have people for health technology. New sensor technologies are who look at boxes in really different ways. For this enabling wearable technologies and the collection reason, CBB encourages and actively supports of information that was not available before. With networking and academic events that will this new information, customized treatments and continually broaden our outlook and perspectives. preventions, personalized healthcare is becoming possible and affordable. Just as the Internet Partnerships are essential to the CBB mission and we revolutionized how we work and communicate, take our national and international partnerships very new biotechnologies and biomedical devices have seriously. We work to establish strong relationships the potential to dramatically change how we live. with companies but also with healthcare industries, government at all levels and other institutions. – CATHERINE BURNS, PhD, Director, Centre for Bioengineering CBB strongly encourages student engagement, and Biotechnology UNIVERSITY OF WATERLOO | THE CENTRE FOR BIOENGINEERING AND BIOTECHNOLOGY 1

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UNIVERSITY OF for health technology.” for to be a r to the next decade promises decade promises the next “ vision and mission

“With a focus on industry partnerships and cross-disciplinary research excellence, the Centre for Bioengineering and Biotechnology (CBB) embodies and advances Waterloo’s research strategy of changing lives and the world we live in through high-impact, highly-relevant transformational research. A deep and varied expertise at the CBB will further bioengineering and biotechnology, set standards for research partnerships at Waterloo, and improve quality of life and human health around the world.”

– D. GEORGE DIXON, PhD, Vice-President, University Research, University of Waterloo

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MISSION

VISION AND VISION

osters the formation the formation osters obust hub for technology technology hub for obust y of Engineering y of Science , Associate Director Director C. CHARLES, Associate TREVOR Facult , Associate Director Director , Associate S. KARIM KARIM Facult Bioengineering and Biotechnology for Center Bioengineering and Biotechnology for Center

– – startups and over the past four years, years, four the past and over startups role in an influential CBB has played innovations university fast-tracking in bioengineering and biotechnology players.” industry key towards The Waterloo-Toronto corridor is fast is fast corridor The Waterloo-Toronto a r becoming CBB is responsive to the needs of its the needs of its to CBB is responsive It f members. has and teams, of interdisciplinary part of the an integral become fast ecosystem.” innovation Waterloo

“ “ the University of Waterloo’s reputation for its innovations its innovations for reputation of Waterloo’s the University engthen in biotechnology and bioengineering in biotechnology Str 1. Pursue leading edge research multi-disciplinary partnerships effective 2. Create 3. CBB’s vision is to be a world leader in bioengineering and leader be a world is to vision CBB’s multidisciplinary strategic facilitate is to Its mission biotechnology. sciences, life to applies technology that research and transdisciplinary It is challenges. industrial and environment human health, the and local, national building strong to in its approach collaborative organizations, healthcare industry, with partnerships international other academic institutions and government. other academic institutions facts and figures CBB is growing fast. Established in 2011, it is already one of the largest research centres in membership at Waterloo. It has attracted some of Waterloo’s most recognized and highly respected researchers across the campus.

faculty student 150+ members 120+ members

departments 16 Royal Society of Canada Fellows 4 faculties 3

in words: » Experienced at working with industry 9 Canada » World-class expertise Research » Multidisciplinary research and lab facilities » 9th overall U15 NSERC funding awarded in the past Chairs 14 years within CBB’s research areas

NSERC Industrial University 3 Research Chairs 7 Research Chairs

4 UNIVERSITY OF WATERLOO | THE CENTRE FOR BIOENGINEERING AND BIOTECHNOLOGY THE FIRST 4 YEARS ...

» 71% increase in faculty membership base

» 17 seminars and lectures

» 5 distinguished lectures

» 2 academic-industry networking forums

» 2 conferences

» 3 workshops

» 2 international research partnership collaborations

» 106+ networking activities/events

CBB’s influence on grants received within the biotechnology/bioengineering/biomedical areas:

» 9% influence across 4 faculties

» 16% influence in Science and Engineering faculties

OVERALL FUNDING FOR ALL FACULTIES 20M UNIVERSITY OF WATERLOO 15M AMOUNT IN MILLIONS

10M “CBB connects me | THE CENTRE FOR BIOENGINEERING AND BIOTECHNOLOGY to the research 5M that facilitates

0M 07/08 08/09 09/10 10/11 11/12 12/13 13/14 14/15 innovations.” BEFORE CBB AFTER CBB – JASON DOWD, PhD, Director, Product Development, Senate approved Nov. 2011 Biopharmaceutical Division, Apotex Inc.

5 research impact

CBB has a substantial and significant faculty and student membership spanning across multiple Faculties to address major research challenges.

“CBB is on the forefront of cross-cutting research in areas of major international strategic importance. This research will impact the Canadian economy with the generation of valuable IPs, patents and HQP trainees for the growing interconnections of human wellness and the health ecosystem.”

– MURRAY MOO-YOUNG, PhD, PEng, FAIMBE, FRSC, Distinguished Professor Emeritus, University of Waterloo

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IMPACT IMPACT

tion,

RESEARCH RESEARCH ts ts emen BIOPROCESSING AND BIOPROCESSING 16 FOOD TECHNOLOGY FOOD HEALTHCARE SYSTEMS HEALTHCARE er, infection testing, testing, infection er, tation, sensors, technologies, technologies, sensors, tation, er imaging, diabetes, er imaging, diabetes, 30 IMAGING

or medical implan ENVIRONMENTAL TECHNOLOGY ENVIRONMENTAL 37 s (fitness, continuous healthcontinuous s (fitness, 40 WEARABLE AND HEALTHCARE DEVICES WEARABLE AND HEALTHCARE orneal and coronary, heart orneal and coronary, 42 BIOMEDICAL ENGINEERING

75 analysis, and processing analysis, large area digital medical imaging area large biomedical and scientific image classifica biomedical and scientific Biomedical imaging and biosensor technologies Biomedical imaging and High-throughput systems and microfluidics systems High-throughput Mobile health and health informatics Mobile health and health monitoring, fall prevention, Alzheimer’s) prevention, fall monitoring, lab-on-a-chip) drinking water, ophthalmic instrumen ophthalmic ultrasound) design (MRI, CT, and hardware sensor wearable canc (skin diagnostics (c monitoring interaction human-robot rhythm, sleep) rhythm, devices assistive smart technology f smart technology Electromagnetic and photonic treatment technologies treatment and photonic Electromagnetic diagnostics (skin canc (skin diagnostics Alzheimer’s, glaucoma, blindness and retinal diseases) and retinal blindness Alzheimer’s, glaucoma, 3D imaging sensors and measur 3D imaging sensors

IMAGING members CBB faculty 37 » » » BIOMEDICAL SYSTEMS AND BIOMEDICAL SYSTEMS DEVICE TECHNOLOGIES » » » » » » » » DEVICES WEARABLE AND HEALTHCARE members CBB faculty 42 » » » » CBB RESEARCH GROUPS clinical diagnostic systems systems clinical diagnostic workflow systems workflow analytics health informatics management health informatics drug delivery systems drug delivery biofuels air pollution control filtration processes filtration water and wastewater treatment treatment and wastewater water bioremediation environmental monitoring monitoring environmental fermentation technology fermentation waste utilization waste protein and pharmaceutical products and pharmaceutical protein separation and filtration bioprocessing and filtration separation baking process packaging food safety food food production and processing production food disinfection and sterilization technologies and sterilization disinfection pathogen detection pathogen optics, spectroscopy, microscopy optics, spectroscopy, biomechanics, mechatronics, assistive devices assistive biomechanics, mechatronics, protein engineering protein genetic engineering genetic diagnostic and lab-on-a-chip devices and lab-on-a-chip diagnostic Bionano-derivatives for functional materials functional for Bionano-derivatives systems drug delivery Biomass and environmental bioremediation and environmental Biomass and applications systems Biopharmaceutical and high-value bioproducts and high-value Biopharmaceutical interface design interface microfluidics and nanofluidics microfluidics

» » » » » HEALTHCARE SYSTEMS HEALTHCARE members 30 CBB faculty » » » » » » ENVIRONMENTAL TECHNOLOGY ENVIRONMENTAL members 40 CBB faculty » » » » » » » » » » BIOPROCESSING AND FOOD TECHNOLOGY AND FOOD BIOPROCESSING members 16 CBB faculty » » » » » » » » » » (6) groups research multidisciplinary BIOMEDICAL ENGINEERING members CBB faculty 75 » » BIOMATERIALS AND BIOMATERIALS INNOVATIONS BIOMANUFACTURING priority areas (2) areas priority scientific outreach “CBB is an excellent research centre that ties together Waterloo’s diverse strengths in biotechnology and offers a great platform for building collaborations.”

– BRIAN FOODY, MME, President and CEO, Iogen Corporation

8 UNIVERSITY OF WATERLOO | THE CENTRE FOR BIOENGINEERING AND BIOTECHNOLOGY UNIVERSITY OF WATERLOO | THE CENTRE FOR BIOENGINEERING AND BIOTECHNOLOGY 9

erials: a scientist’s journey from fundamental science science fundamental from journey erials: a scientist’s acturing Academic Industry Forum”, University University Forum”, Industry Academic acturing unding Opportunities” Shaylene Nancekivell, Nancekivell, unding Opportunities” Shaylene : How to Start a Spinoff Company: Some Key Steps and Steps Key Some Company: a Spinoff Start to : How and Challenges in Global Health and Development” Peter Peter Health and Development” and Challenges in Global entres of Excellence, June 18, 2014 of Excellence, entres Angle View of Vaccine R&D and Manufacturing” Donald F. Gerson, Donald F. and Manufacturing” R&D of Vaccine Angle View xt 3 Billion” Suneet Singh Tuli, BASc, CEO, Datawind Inc., Datawind CEO, BASc, Singh Tuli, 3 Billion” Suneet xt opp, University of Waterloo, January 8, 2014 of Waterloo, University opp, celerating Academic Research into Commercial Impact” Charles L. Impact” Commercial into Research Academic celerating Business Development Specialist, Waterloo Mitacs, April 7, 2016 Mitacs, April 7, Waterloo Specialist, Development Business of Waterloo — Ontario Centres of Excellence, January 19, 2016 January 19, of Excellence, Centres — Ontario of Waterloo November 11, 2014 November “Devices and Sensors Academic Industry Forum”, University of Waterloo — of Waterloo University Forum”, Industry Academic and Sensors “Devices C Ontario & Biomanuf “Biomaterial writing tips” changes and grant on open program Session Info “CIHR C Leslie “The Ne “The Who Can Help” Benton Leong, Investor; Member, Selection Committee, Committee, Selection Member, Investor; Leong, Help” Benton Can Who 11, 2015 December Angelnet, Golden Triangle and F “Mitacs Programs to creating value to society” Cynthia Goh, PhD, Director, Impact Centre and Centre Impact Director, Goh, PhD, Cynthia society” to value creating to 2015 30, September of Toronto, University of Chemistry, Department Professor, Workshop “CBB Singer, PhD, CEO, Grand Challenges Canada, October 5, 2015 October Challenges Canada, Grand CEO, PhD, Singer, “Ac Emeritus, Director Chemical Engineering and Faculty Professor, PhD, Cooney, 6, 2015 November MIT, Innovation, Technological for Deshpande Center Wide- “A 2015 27, Inc., March PnuVax and CEO, Co-Founder PhD, nanomat and “Biosensors “Tackling Gr “Tackling

» » (3) CBB WORKSHOPS » » ACADEMIC — INDUSTRY NETWORKING FORUMS (2) FORUMS NETWORKING — INDUSTRY ACADEMIC special events (5) LECTURES DISTINGUISHED Lectures: and Innovation Visionary » » » » » » CONFERENCES (2) » “Imaging Lipids in the Vulnerable Brain” Shawn Whitehead, PhD, Assistant Professor, Depts. Anatomy and » Biophysical Society of Canada Conference, Cell Biology; Clinical Neurological Sciences, Western University of Waterloo, June 17-19, 2015 University, November 27, 2014

» Waterloo Region MED TECH 2016 Conference, » “Exercise Training in Adverse Cardiac Remodeling” Grand River Hospital Freeport Campus, May 25, 2016 Dirk J. Duncker, PhD, Professor of Experimental Cardiology, Erasmus University, The Netherlands, April 2, 2015

» “Persuasive Health Technology to Improve Health GUEST LECTURES/SEMINARS (17) and Wellbeing” Olga Kulyk, PhD, Assistant Professor, National Biotechnology Week Celebration Events (4) Persuasive Health Technology Lab, Center for » “Ontario Life Sciences Sector — Challenges and eHealth, University of Twente, Enschede, The Netherlands, Opportunities” Jason Field, PhD, Executive Director, May 27, 2015 Life Sciences Ontario, September 19-20, 2013 » “Zebra Mussel-inspired Electrically Conductive Polymer » “Biofuels and Waste Treatment” and “Biotechnology: Nanofiber” Boxin Zhao, PhD, and Wei Zhang, Department of Innovations in Imaging” Panel Discussion and Presentations, Chemical Engineering, University of Waterloo, June 11, 2015 September 29-October 1, 2014 » “Mussel Power: Defining the Essentials for Translation » “Fermentology: Innocente Brewery. From Academic to to Technology” J. Herbert Waite, PhD, Professor of Fermentologist” Steve Innocente, PhD, Head Brewer and Biochemistry, Departments of Molecular Cell and Owner, Innocente Brewing Company, November 6, 2015 Developmental Biology and Chemistry & Biochemistry, University of California, Santa Barbara (UCSB), » “CBB Panel Discussion: Engaging Hospitals in Research August 13, 2015 Projects” June 17, 2016 » “A tissue mechanist found in translation” Thomas Biomedical Discussion Group Lectures (13) Willett, PhD, Assistant Professor, Systems Design » “Translational studies of sodium nitrite supplementation to Engineering, University of Waterloo, November 19, 2015 reverse arterial aging” and “Healthy ways to delay vascular » “Ultrasound imaging innovations for live monitoring aging” Douglas R. Seals, PhD, Department of Integrative of complex flow dynamics” Alfred Yu, PhD, Associate Physiology, University of Colorado, September 11, 2013 Professor, Electrical and Computer Engineering, » “Bio-MEMS Seminar: “High-Throughput Analysis of Protein- University of Waterloo, October 29, 2015 Protein Interactions Using Droplet-based Microfluidics” » “Nanostructured based Lab-on-chips for optical and Soo-Ik Chang, PhD, Professor of Biochemistry, Chungbuk electrical detection” Sara Mahshid, Postdoc, Leslie Dan National, October 24, 2013 Faculty of Pharmacy, University of Toronto, April 14, 2016 » “Seeing cells in the living eye: Pushing the limits of high-resolution retinal imaging” Jennifer Hunter, PhD, Assistant Professor, Departments of Ophthalmology, STUDENT GROUPS (3) Biomedical Engineering, and Center for Visual Science, University of Rochester,” October 24, 2013 CBB provides in-kind and seed funding support to student groups on campus for their operations and » “Heart Wall Myofibers are Arranged in Minimal Surfaces” outreach activities. Kaleem Siddiqi, PhD, Professor and William Dawson » Engineers in Medicine Scholar, School of Computer Science, McGill University, » uwDNA October 25, 2013 » International Genetically Engineered Machine (IGEM) » “FDA’s role in regulating medical devices: premarket and scientific research programs” Yuan Fang, PhD, Regulatory Scientist, U.S. Food and Drug Administration (FDA), September 10, 2014

10 UNIVERSITY OF WATERLOO | THE CENTRE FOR BIOENGINEERING AND BIOTECHNOLOGY UNIVERSITY OF WATERLOO | THE CENTRE FOR BIOENGINEERING AND BIOTECHNOLOGY 11 and implementing new technologies for the industry.” the industry.” for technologies new and implementing “IFPT and CBB have many common interests and have effectively effectively and have interests common many have and CBB “IFPT collaborated in the development of research projects for the food food the for projects of research in the development collaborated strengthening our collaboration as we work together on developing on developing together work as we our collaboration strengthening , MSc, Chair, Institute of Food Processing Technology and Trades and Apprenticeship (Millwright), Conestoga College Conestoga (Millwright), Apprenticeship and and Trades Technology Processing of Food Institute GARCIA, MSc, Chair, LUIS – industry. We value the support received from CBB and look forward to to and look forward CBB from the support received value We industry. prestigious awards research and recognition CANADA RESEARCH CHAIRS (9) chairs and » CLARK DICKERSON, PhD, Kinesiology; Shoulder Mechanics Understanding the mechanics of the human shoulder. His research will improve our understanding of the fundamental causes awards of shoulder damage and prompt changes to our workplaces and daily lives that will protect shoulders and improve the lives of Canadians.

“Our company came to the CBB looking » BRIAN DIXON, PhD, Biology; Fish and Environmental Immunology for new medical imaging ideas and Understanding fish immunology and applying it to environmental problems has partnered with researchers to such as climate change. His research will lead to increased knowledge and policies commercialize new technologies for the to preserve fisheries, threatened cold water species and aquaculture stocks.

x-ray imaging field. We believe the CBB » FRANK GU, PhD, Chemical Engineering; Advanced Targeted Delivery Systems creates a valuable ecosystem in which Reducing eye injections by using nanoparticles. His research will lead industry and academic researchers can to new ways to treat eye diseases. » MING LI, PhD, Computer Science; collaborate to bring new ideas to market Bioinformatics Predicting protein structures. This and we look forward to the continued research will make genome mapping, homology searches and determining collaboration programs.” protein structures more efficient by developing tools in bioinformatics.

» JOHN MCPHEE, PhD, Systems Design – GEORGE PINHO, PhD, MBA, President, Christie Medical Holdings, Inc. Engineering; Biomechatronic System Dynamics System Dynamics: From Cars to Humans. His research will result in innovative mechatronic and biomechanical systems that will improve the performance of elderly, athletes and persons with disabilities.

12 UNIVERSITY OF WATERLOO | THE CENTRE FOR BIOENGINEERING AND BIOTECHNOLOGY UNIVERSITY OF WATERLOO | THE CENTRE FOR BIOENGINEERING AND BIOTECHNOLOGY 13

ersités. ersités. , Distinguished Professor Professor , Distinguished , Professor, Department Chair, Kinesiology Chair, Department , Professor, és, France, “Trans-disciplinary “Trans-disciplinary és, France, , PhD, Professor, Chemical Engineering Professor, , PhD, PhD, Professor; Director, Centre for for Centre Director, Professor; PhD, , PhD, Distinguished Professor Professor Distinguished OUNG, PhD, ofessor, Computer Science Computer ofessor, e, with University of Twente’s expertise in expertise of Twente’s with University e, , PhD, Professor, Mechanical Professor, , PhD, ersity of Waterloo. of Waterloo. ersity , PhD, Professor, Mechanical Professor, , PhD, YSERKANI JONES, tions, academic exchanges and innovation actions and innovation tions, academic exchanges a er scienc , PhD, Professor, Physics and Astronomy Physics Professor, , PhD, FORREST t the Univ t the Sorbonne Univ ta Driven Persuasive Technology”, 2015 Technology”, Persuasive ta Driven 16 a omput ollabor PhD, Pr MING LI, PhD, MOO-Y MURRAY Netherlands, The of Twente, University “Da JAMES JAMES LYNDON Contact Lens Research, Optometry and Vision Science and Vision Optometry Research, Lens Contact in health, engineering, and strengths CBB’s Combining c Emeritus, Chemical Engineering , PhD, Professor, Chemical Engineering Professor, PU CHEN, PhD, , PhD BILL MCILROY TAM MICHAEL K.C. TO EHSAN and Mechatronics Engineering and Mechatronics of Twente in June 2016 and a second workshop in November in November workshop and a second in June 2016 of Twente a 2016 the University held at was participating 25 researchers in October workshop with a second 2016 in May of Waterloo 20 , PhD JOHN THOMPSON Emeritus, Biology international this will be one of the largest social sciences, persuasive in data-driven together work to assembled teams in the involved 20 researchers with over technology, at the University was held workshop first The collaboration. Sorbonne Universit in Health Engineering”, 2016 Innovation scientific enable concrete seeks to partnership This c Health of Innovative in the area partners the two between over workshop with first The Engineering Technologies. NORMAN ZHOU Engineering and Mechatronics 

 » » RESEARCH INTERNATIONAL (2) PARTNERSHIPS » UNIVERSITY RESEARCH CHAIRS (7) RESEARCH UNIVERSITY » » » (3) FELLOWS OF CANADA SOCIETY ROYAL scholar. Canadian a for accolade is the highest FRSC » » » » » » » »

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vices for early diagnosis and early diagnosis for vices , Cheriton School of Computer Science; Science; School of Computer , Cheriton esults in medical imaging diagnos AVI-NAEINI, Electrical and Electrical AVI-NAEINI, , PhD, Systems Design Engineering; Design Systems , PhD, ts and de ts with health car tions such as v tigating ways to develop math-based models math-based develop to ways tigating os es trumen v PETER HUCK, PhD, Civil and En PETER HUCK, PhD, CAROLYN REN, PhD, Mechanical and Mechatronics and Mechatronics Mechanical PhD, REN, CAROLYN T Lab-on-a-Chip Engineering; Investigating the presence of known and emerging and emerging of known the presence Investigating Engineering; Water Treatment Engineering; Water in source contaminants chemical and microbial the for technologies the evolving and waters; of these contaminants. removal lead to hand-held devices for point-of-care diagnosis; reducing diagnosis; reducing point-of-care for hand-held devices lead to the c A laboratory in the palm of your hand. This research will research hand. This palm of your in the A laboratory Computer Engineering; In Intelligent Integrated Integrated Engineering; In Intelligent Computer Electromagnetic and Novel Systems Radio/Antenna Media Technologies the investigate with BlackBerry to In collaboration designs and computational human body interactions and methodologies. SAFIEDDIN SAF SAFIEDDIN JOHN MCPHEE, PhD, S JOHN MCPHEE, PhD, on automotive with a focus simulations, and computer applica vehicles. electric and hybrid miniaturizing, of sensor networks, generation next  Micro and Nanodevices Micro and nanotechnologies. diseases with micro Treating medical of new development will lead to research This ins to and savings outcomes patient better lead to to order and Design Modelling Mathematics-Based are they with Maplesoft and Toyota In collaboration in JUSTIN WAN, PhD WAN, JUSTIN Computing Scientific will lead to the development of new medical imaging of new the development will lead to of cancer. early detection for technologies and analysis JOHN YEOW is aimed His research and Body. the Ailing Brain Visualizing systems. the health-care ALEXANDER WONG, PhD WONG, ALEXANDER His research cancer. detect to Imaging technologies  Medical Imaging Systems of diseases. therapy surgery in computer-aided techniques simulation improving at and enhancing r

» » NSERC INDUSTRIAL RESEARCH CHAIRS (3) NSERC INDUSTRIAL » » » » » BOARD OF DIRECTORS

UNIVERSITY OF WATERLOO boards, REPRESENTATIVES: » Pearl Sullivan, PhD, Dean of Engineering

» Robert Lemieux, PhD, Dean of Science

» Chris Backhouse, PhD, Professor, Electrical committees and Computer Engineering » Eric Croiset, PhD, Professor and Chair, Chemical Engineering

» Sue Horton, PhD, Professor, CIGI Chair in and staff Global Health Economics, School of Public Health and Health Systems

» Jan Huisson, PhD, Professor and Chair, Mechanical and Mechatronics Engineering

“GE Healthcare Life Science is a » Elizabeth Meiering, PhD, Professor, Chemistry strong supporter of CBB. As an Industry » Carolyn Ren, PhD, Professor, Mechanical and Mechatronics Engineering Advisory Board member, I’ve seen INDUSTRY, GOVERNMENT AND first-hand the high quality of innovations INSTITUTIONAL REPRESENTATIVES: » Doug Dittmer, MD, Director of Physical emerging from this multidisciplinary Medicine, Grand River Hospital Freeport Campus approach. I’ve seen how CBB innovators » Andriy Lomako, Director of Business Development, Teledyne DALSA

are gearing their research to solve current » Tyler Whale, PhD, President, Ontario issues and bottlenecks in my industry. Agri-Food Technologies » Aldo Badano, PhD, Acting Deputy Director, This is exactly the type of approach FDA (past member) » George Pinho, PhD, MBA, President, Christie we need in universities.” Medical Holdings, Inc. (past member)

– FIONA FITZGERALD, BSc (Hons), National Zone Leader, Life Science, GE Healthcare Canada

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sity of Waterloo sity , PhD, Associate Professor, Professor, Associate , PhD, ey , PhD, Project Manager Project , PhD, , Administrative Assistant Assistant , Administrative owski , PhD, Professor, Electrical and Electrical Professor, , PhD, , PhD, Associate Director — Faculty of Engineering — Faculty Director Associate , PhD, , PhD, Professor, Electrical Professor, , PhD, avi-Naeini , MA, Business Development Director Development , MA, Business ton , PhD, Professor, Physics Physics Professor, ampbell, PhD, , PhD, Associate Professor, Chemical Engineering, Professor, Associate , PhD, , PhD, Associate Professor, Systems Design Systems Professor, Associate , PhD, eow , PhD, Associate Director — Faculty of Science — Faculty Director Associate C. Charles, PhD, vor , PhD, Professor, Biology, Biology, Professor, C. Charles, PhD, vor , PhD, Director Burns, PhD, Catherine S. Karim Karim Tre Fen Shirley Prince Chekema Bednar Krystina , PhD, Associate Professor, Chemical Professor, Associate , PhD, Aucoin Marc Univer Engineering, Melanie C Waterloo of University and Astronomy, Tre of Waterloo University S. Karim Karim of Waterloo Engineering, University Computer McConk Brendan of Waterloo University Biology, Safieddin Saf John Y of Waterloo Engineering, University Gu Frank member) (past of Waterloo University and Computer Engineering, University of Waterloo Engineering, University and Computer

» STAFF » » » » » OPERATIONS COMMITTEE OPERATIONS » » » » » » » » , PhD, MBA, VP, Product R&D — Global, Sanofi R&D Pasteur Product VP, MBA, , PhD, D’AMORE TONY –

the reputation of Canada in the international biotechnology arena.” arena.” biotechnology of Canada in the international the reputation for interaction between academic scientists and industry. CBB provides a a CBB provides and industry. academic scientists between interaction for significant benefit to the Canadian biotechnology industry by supporting by supporting industry to the Canadian biotechnology benefit significant esident and CEO, PnuVax Inc. PnuVax and CEO, esident “The Centre for Bioengineering and Biotechnology has created a great forum forum a great has created Bioengineering and Biotechnology for Centre “The research, contributing to the development of scientific talent, and enhancing and enhancing talent, of scientific the development to contributing research, esident and CEO, Iogen Corporation Iogen and CEO, esident tegrated CIO, Grand River Hospital/ River Grand CIO, tegrated , MBA, President, Christie Medical Christie President, , MBA, , BSc (Hons), National Zone Leader — Leader Zone National , BSc (Hons), , PhD, Ex-officio, Director, Centre for Centre Director, Ex-officio, , PhD, , PhD, FRSC, Distinguished Professor Professor Distinguished FRSC, , PhD, Young , MEcon, Director, Emerging Technologies Technologies Emerging Director, son, MEcon, , PhD, Director of Product Development — Development of Product Director , PhD, wd , PhD, MBA, VP, Product R&D — Global R&D Product VP, MBA, , PhD, Amore oga College , MSc, Chair, Institute of Food Processing Processing of Food Institute , MSc, Chair, arcia t e-President, University Research, University of Waterloo University Research, University e-President, , PhD, FRSC, Chair, Associate Associate Chair, FRSC, , PhD, John Thompson Vic Tim Karls Tim Technology and Trades and Apprenticeship (Millwright), and Apprenticeship and Trades Technology Cones Moo- Murray of Waterloo Emeritus, Chemical Engineering, University , PhD Pinho George Holdings, Inc. Luis G Pr Donald Gerson, PhD, Gary Higgs, MMSc, In Jason Do Fiona Fitzgerald , MME, Pr Brian Foody Hospital Mary’s St. member) (past Canada Industry Directorate, Catherine Burns Catherine D’ Tony  Bioengineering and Biotechnology Pasteur Sanofi Inc. Apotex Biopharmaceuticals, Canada GE Healthcare Science, Life , MSc, VP Mobile Computing, BlackBerry , MSc, VP Mobile Computing, Cotter Frank ADVISORY BOARD ADVISORY » » » » » » » » » » » » » CBB members

“CBB is on the leading edge of research and innovation that cut across traditional disciplines. With its focus on multidisciplinary research, CBB is building a strong, strategic, international footprint in the globally important areas of bioengineering and biotechnology.”

– JOHN THOMPSON, PhD, FRSC, Associate Vice-President, University Research, University of Waterloo

16 UNIVERSITY OF WATERLOO | THE CENTRE FOR BIOENGINEERING AND BIOTECHNOLOGY UNIVERSITY OF WATERLOO | THE CENTRE FOR BIOENGINEERING AND BIOTECHNOLOGY 17 CBB CBB MEMBERS stems trical and Computer Engineering trical and Computer omputer Engineering omputer stems Design Engineering stems trical and Computer Engineering trical and Computer ysics and Astronomy ysics , Cheriton School of Computer Science School of Computer , Cheriton chitecture , Chemistry , Systems Design Engineering , Systems , Chemical Engineering , School of Public Health & Health Systems ocha, School of Public Health , Mechanical and Mechatronics Engineering , Mechanical and Mechatronics ashekar ystems Design Engineering ystems , School of Pharmacy sics and Astronomy , Biology , Chemical Engineering , School of Pharmacy , Cheriton School of Computer Science School of Computer an, Cheriton trical and Computer Engineering trical and Computer , Civil and Environmental Engineering ah, Civil and Environmental t, Chemical Engineering , Physics and Astronomy , Physics a Bizheva ystems Design Engineering ystems , Civil and Environmental Engineering odland, Civil and Environmental oin, Chemical Engineering , Kinesiology y Acker evor evor Charles, Biology Perry Chou, Chemical Engineering Perry Clausi, S David Donald Cow Eric Croise , Elec Bo Cui Damen, Elec Mohamed Oussama , Kinesiology Clark Dickerson , Biology Brian Dixon Dixon George Wayne Br Wayne Budman Hector Burns Catherine , Ph Melanie Campbell , S Shi Cao Chandr Naveen Tr Helen Chen, School of Public Health & Health Sy Jeff Chen, Phy Pu Chen, Chemical Engineering Chris Backhouse, Elec Gladimir Baranoski Baugh Jonathan Beazely Mike , Ar Philip Beesley Kostadink Blay Jonathan Niels Bols, Biology and C Slim Boumaiza, Electrical Eihab Abdel-Rahman, Sy Stace Al-May Adil Bill Anderson Ar Jose (Frank) Auc Marc 

» » » » » » » » » » » » » » » » » » » » » » » » » » » » 150 UWATERLOO FACULTY MEMBERS FACULTY 150 UWATERLOO » » » » » » » Andrew Doxey, Biology » Dana Kulic, Electrical and Computer Engineering » Bernard Duncker, Biology » Andrew Laing, Kinesiology » David Edwards, School of Pharmacy » Vasudevan Lakshminarayanan, Optometry and Vision Science » Monica Emelko, Civil and Environmental Engineering » Edith Law, Cheriton School of Computer Science » Kaan Erkorkmaz, Mechanical and Mechatronics Engineering » Hyung-Sool Lee, Civil and Environmental Engineering » Shahrzad Esmaeili, Mechanical and Mechatronics Engineering » Raymond Legge, Civil and Environmental Engineering » Baris Fidan, Mechanical and Mechatronics Engineering » Zoia Leonenko, Physics and Astronomy » Paul Fieguth, Systems Design Engineering » Bosco Leung, Electrical and Computer Engineering » Marianna Foldvari, School of Pharmacy » Kam Tong Leung, Chemistry » James Forrest, Physics and Astronomy » Peter Levine, Electrical and Computer Engineering » Lora Giangregorio, Kinesiology » Dongquing Li, Mechanical and Mechatronics Engineering » Bernard Glick, Biology » Ming Li, Cheriton School of Computer Science » Maud Gorbet, Systems Design Engineering » Juewen Liu, Chemistry » Kelly Grindrod, School of Pharmacy » Kesen Ma, Biology » Frank Gu, Chemical Engineering » Chandra Madhuranthakam, Chemical Engineering » J Guy Guillemette, Chemistry » Vivek Maheshwari, Chemistry » Bae-yeun Ha, Physics and Astronomy » Mungo Marsden, Biology » Arsen Hajian, Systems Design Engineering » Brendan McConkey, Biology » John Heikkila, Biology » Bill McIlroy, Kinesiology » Jonathan Histon, Systems Design Engineering » Ken McKay, Management Sciences » Danny Ho, School of Pharmacy » Ian McKillop, School of Public Health & Health Systems » Jesse Hoey, Cheriton School of Computer Science » John McPhee, Systems Design Engineering » Laurie Hoffman-Goetz, School of Public Health » Elizabeth Meiering, Chemistry and Health Systems » Barbara Moffatt, Biology » John Honek, Chemistry » Murray Moo-Young, Chemical Engineering » Sue Horton, School of Public Health & Health Systems » Christine Moresoli, Chemical Engineering » Peter Huck, Civil and Environmental Engineering » David Nairn, Electrical and Computer Engineering » Chris Hudson, Optometry and Vision Science » Patricia Nieva, Mechanical and Mechatronics Engineering » Richard Hughson, Kinesiology » Jeff Orchard, Cheriton School of Computer Science » Jan Huissoon, Mechanical and Mechatronics Engineering » Osman Ozaltin, Management Sciences » Stefan Idziak, Physics and Astronomy » Katerina Papoulia, Applied Math » Brian Ingalls, Applied Math » Praveen Rao Perampallio Nekkar, School of Pharmacy » Ning Jiang, Systems Design Engineering » Sean Peterson, Mechanical and Mechatronics Engineering » Lyndon Jones, Optometry and Vision Science » Kumaraswamy Ponnambalam, Systems Design Engineering » Vassili Karanassios, Chemistry » Pascal Poupart, Cheriton School of Computer Science » Karim Karim, Electrical and Computer Engineering » Eric Prouzet, Chemistry » Behrad Khamesee, Mechanical and Mechatronics Engineering » Omar Ramahi, Electrical and Computer Engineering » Jonathan Kofman, Systems Design Engineering » Bruce Reed, Biology » Mohammad Kohandel, Applied Mathematics » Carolyn Ren, Mechanical and Mechatronics Engineering

18 UNIVERSITY OF WATERLOO | THE CENTRE FOR BIOENGINEERING AND BIOTECHNOLOGY UNIVERSITY OF WATERLOO | THE CENTRE FOR BIOENGINEERING AND BIOTECHNOLOGY 19 CBB CBB MEMBERS tronics Engineering tronics onics Engineering tronics Engineering tronics omputer Engineering omputer vironmental Engineering vironmental than, Applied Mathematics ystems Design Engineering ystems trical and Computer Engineering trical and Computer , Electrical and Computer Engineering and Computer , Electrical d, Biology , Kinesiology v, Chemical Engineering , School of Pharmacy cev , Systems Design Engineering , Systems tt , Electrical and Computer Engineering and Computer , Electrical avi-Naeini , Chemistry , Biology , Cheriton School of Computer Science School of Computer , Cheriton , Systems Design Engineering , Systems , Systems Design Engineering , Systems C. Wong , Mechanical and Mechatronics Engineering , Mechanical and Mechatronics serkani , Biology th Vijayan , Physics and Astronomy vick, Physics , Systems Design Engineering izhoosh, Systems , Electrical and Computer Engineering and Computer , Electrical achdev , Management Sciences , Management Safa enay , Mechanical and Mechatronics Engineering en, Mechanical and Mechatronics , School of Pharmacy Wettig , Applied Mathematics w Scott , Chemistry aylor , Electrical and Computer Engineering and Computer , Electrical Yu an der Meer, Biology Zhao, Chemical Engineering , Systems Design Engineering , Systems y Scott , Systems Design Engineering , Systems Wong , School of Public Health and Health Systems Stolee Norman Zhou, Mechanical and Mechatr David Ye David Alfred Boxin Andrew K. Andrew John Yeow Thomas Wille Thomas Alex Richard Wells Richard John W Shawn Justin Wan Justin , Elec Zhou Wang , Mechanical and Mecha James Tung V Matt Mathilaka Hamid T Ehsan Toy , Civil and En Neil Thomson , Biology John Thompson , Chemical Engineering Michael Tam Tang Shirley T Scott , S Daniel Stashuk Paul Roderick Slav Roderick Spaffor David , Electrical and C Raed Shubair, Electrical Simako David Sivalogana Sivabal Stace Shaker George Safieddin Saf Armaghan Salehian, Mechanical and Mecha Matthe Manoj S Er Fatih , School of Public Health & Health Systems Public Health & Health , School of Riley Barbara Rose David

» » » » » » » » » » » » » » » » » » » » » » » » » » » » » » » » » » » » » » » pathway to innovation

20 UNIVERSITY OF WATERLOO | THE CENTRE FOR BIOENGINEERING AND BIOTECHNOLOGY a

UNIVERSITY OF WATERLOO | THE CENTRE FOR BIOENGINEERING AND BIOTECHNOLOGY 21

INNOVATION PATHWAY TO TO PATHWAY oncept of CBB as a large extended family family extended of CBB as a large oncept tworking sessions, inspirational speakers, speakers, sessions, inspirational tworking ers innovative thinking among its members by supporting supporting by among its members thinking innovative ers athway to Innovation,” Industrial Biotechnology 9 (5), 258-259 (2013). 9 (5), 258-259 Biotechnology Industrial Innovation,” to athway egory in the region, and one of the fastest growing. Researchers Researchers growing. and one of the fastest egory in the region, , PhD, Director, Centre for Bioengineering and Biotechnology for Centre Director, BURNS, PhD, CATHERINE “P Ref: CBB hosts regular ne regular CBB hosts CBB fost a culture of partnership and collaboration. One of the mandates One of the mandates and collaboration. of partnership a culture academic silos traditional through break is to behind the Centre in different researchers between interaction encouraging by perspectives. disciplines, and with different different in departments, pays dividends in enhanced research productivity.” research dividends in enhanced pays and small informal group interactions to encourage creative thinking thinking creative encourage to interactions group and small informal This c and mentoring.  Biotechnology and medical devices is the third largest industrial industrial largest is the third and medical devices Biotechnology cat exploring are Bioengineering and Biotechnology for the Centre at biofuels, and new systems, delivery in pharmaceutical advances its high is area of the Waterloo One of the strengths biomaterials. in number. Massachusetts and California rivaling of patents, volume –

  “ UNIVERSITY OF WA TERL OO 519-888-4567, ext. 32732 200 University Avenue West, Waterloo, ON,CanadaN2L3G1 UNIVERSITY OFWATERLOO CENTRE FORBIOENGINEERING ANDBIOTECHNOLOGY (CBB) Tweet us:@WaterlooCBB | cbb@uwat erloo.ca |cbb.uwaterloo.ca | East Campus4,Room 200 1

CONTRIBUTORS: CATHERINE BURNS, KRYSTINA BEDNAROWSKI, SHIRLEY FENTON; PHOTOGRAPHY: BRYN GLADDING, COLIN DEWAR, TUDOR COSTASCHE, UWATERLOO C010195