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Effectiveness of Brief Alcohol Interventions in Primary Care Populations

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Effectiveness of Brief Alcohol Interventions in Primary Care Populations This is a repository copy of Effectiveness of brief alcohol interventions in primary care populations. White Rose Research Online URL for this paper: http://eprints.whiterose.ac.uk/128807/ Version: Published Version Article: Kaner, E.F.S., Beyer, F.R., Muirhead, C. et al. (6 more authors) (2018) Effectiveness of brief alcohol interventions in primary care populations. Cochrane Database of Systematic Reviews, 2018 (2). CD004148. https://doi.org/10.1002/14651858.CD004148.pub4 © 2018 The Cochrane Collaboration. Reproduced in accordance with the publisher's self-archiving policy. Reuse Items deposited in White Rose Research Online are protected by copyright, with all rights reserved unless indicated otherwise. They may be downloaded and/or printed for private study, or other acts as permitted by national copyright laws. The publisher or other rights holders may allow further reproduction and re-use of the full text version. This is indicated by the licence information on the White Rose Research Online record for the item. Takedown If you consider content in White Rose Research Online to be in breach of UK law, please notify us by emailing [email protected] including the URL of the record and the reason for the withdrawal request. [email protected] https://eprints.whiterose.ac.uk/ Cochrane Database of Systematic Reviews Effectiveness of brief alcohol interventions in primary care populations (Review) Kaner EFS, Beyer FR, Muirhead C, Campbell F, Pienaar ED, Bertholet N, Daeppen JB, Saunders JB, Burnand B Kaner EFS, Beyer FR, Muirhead C, Campbell F, Pienaar ED, Bertholet N, Daeppen JB, Saunders JB, Burnand B. Effectiveness of brief alcohol interventions in primary care populations. Cochrane Database of Systematic Reviews 2018, Issue 2. Art. No.: CD004148. DOI: 10.1002/14651858.CD004148.pub4. www.cochranelibrary.com Effectiveness of brief alcohol interventions in primary care populations (Review) Copyright © 2018 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. TABLEOFCONTENTS HEADER....................................... 1 ABSTRACT ...................................... 1 PLAINLANGUAGESUMMARY . 2 SUMMARY OF FINDINGS FOR THE MAIN COMPARISON . ..... 4 BACKGROUND .................................... 6 OBJECTIVES ..................................... 7 METHODS...................................... 7 RESULTS....................................... 12 Figure1. ..................................... 13 Figure2. ..................................... 18 Figure3. ..................................... 19 Figure4. ..................................... 22 Figure5. ..................................... 24 Figure6. ..................................... 25 Figure7. ..................................... 26 Figure8. ..................................... 27 Figure9. ..................................... 28 Figure10. ..................................... 31 ADDITIONALSUMMARYOFFINDINGS . .. 32 DISCUSSION ..................................... 37 AUTHORS’CONCLUSIONS . 40 ACKNOWLEDGEMENTS . 41 REFERENCES ..................................... 41 CHARACTERISTICSOFSTUDIES . .. 52 DATAANDANALYSES. 175 Analysis 1.1. Comparison 1 Brief intervention versus control, Outcome 1 Quantity of drinking (g/week) at 12 months. 179 Analysis 1.2. Comparison 1 Brief intervention versus control, Outcome 2 Quantity of drinking (g/week) at 12 months, restricted to trials at low risk of bias due to allocation concealment. ............... 181 Analysis 1.3. Comparison 1 Brief intervention versus control, Outcome 3 Quantity of drinking (g/week) at 12 months, restricted to trials at low risk of bias due to attrition. ................ 182 Analysis 1.4. Comparison 1 Brief intervention versus control, Outcome 4 Quantity of drinking (g/week) at 12 months, with imputation of unknown standard deviations. ............ 183 Analysis 1.5. Comparison 1 Brief intervention versus control, Outcome 5 Quantity of drinking (g/week) at 12 months, subgrouped by cluster/individual randomisation. .............. 185 Analysis 1.6. Comparison 1 Brief intervention versus control, Outcome 6 Quantity of drinking (g/week) at 12 months, subgrouped by cluster/individual randomisation, varying imputed ICC. 187 Analysis 1.7. Comparison 1 Brief intervention versus control, Outcome 7 Quantity of drinking (g/week) at 12 months, subgroupedbygender.. 189 Analysis 1.8. Comparison 1 Brief intervention versus control, Outcome 8 Quantity of drinking (g/week) at 12 months, subgrouped by gender, excluding trials of men only. ............. 190 Analysis 1.9. Comparison 1 Brief intervention versus control, Outcome 9 Quantity of drinking (g/week) at 12 months, subgrouped by adolescents/young adults only versus other. ................. 192 Analysis 1.10. Comparison 1 Brief intervention versus control, Outcome 10 Quantity of drinking (g/week) at 12 months, subgrouped by general practice/emergency setting. ............ 194 Analysis 1.11. Comparison 1 Brief intervention versus control, Outcome 11 Quantity of drinking (g/wk) at 12 months, subgrouped by intervention modality (advice versus counselling)................. 196 Analysis 1.12. Comparison 1 Brief intervention versus control, Outcome 12 Quantity of drinking (g/week) at 12 months, subgroupedbytypeofcontrol. 198 Analysis 1.13. Comparison 1 Brief intervention versus control, Outcome 13 Quantity of drinking (g/week), subgrouped by lengthoffollow-up.. 200 Effectiveness of brief alcohol interventions in primary care populations (Review) i Copyright © 2018 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. Analysis 1.14. Comparison 1 Brief intervention versus control, Outcome 14 Quantity of drinking (g/week), subgrouped by length of follow-up (6 and 12 months) and restricted to trials with information at both times. 203 Analysis 1.15. Comparison 1 Brief intervention versus control, Outcome 15 Quantity of drinking (g/week) at 12 months, subgrouped by effectiveness/efficacy. 205 Analysis 1.16. Comparison 1 Brief intervention versus control, Outcome 16 Frequency of binge drinking (number binges/week)at12months. 207 Analysis 1.17. Comparison 1 Brief intervention versus control, Outcome 17 Frequency of drinking (number binges/week), subgrouped by length of follow-up (6 & 12 months) and restricted to trials with information at both times. 208 Analysis 1.18. Comparison 1 Brief intervention versus control, Outcome 18 Frequency of drinking (number days drinking/week)at12months. 209 Analysis 1.19. Comparison 1 Brief intervention versus control, Outcome 19 Frequency of drinking (number days drinking/week), subgrouped by length of follow-up (6 & 12 months) and restricted to trials with information at both times. .................................... 210 Analysis 1.20. Comparison 1 Brief intervention versus control, Outcome 20 Intensity of drinking (g/drinking day) at 12 months..................................... 211 Analysis 1.21. Comparison 1 Brief intervention versus control, Outcome 21 Heavy drinkers at 12 months. 212 Analysis 1.22. Comparison 1 Brief intervention versus control, Outcome 22 Binge drinkers at 12 months. 213 Analysis 1.23. Comparison 1 Brief intervention versus control, Outcome 23 Laboratory markers - GGT (IU/L) at 12 months..................................... 214 Analysis 1.24. Comparison 1 Brief intervention versus control, Outcome 24 Laboratory markers - GGT (IU/L) at 12 months, subgrouped by gender. 215 Analysis 2.1. Comparison 2 Extended intervention versus minimal or no intervention, Outcome 1 Quantity of drinking (g/week)at12months. 216 Analysis 2.2. Comparison 2 Extended intervention versus minimal or no intervention, Outcome 2 Frequency of binge drinking (number binges/week) at 12 months. ........ 217 Analysis 2.3. Comparison 2 Extended intervention versus minimal or no intervention, Outcome 3 Frequency of drinking (number days drinking/week) at 12 months. 217 Analysis 2.4. Comparison 2 Extended intervention versus minimal or no intervention, Outcome 4 Intensity of drinking (g/drinkingday)at12months.. 218 Analysis 2.5. Comparison 2 Extended intervention versus minimal or no intervention, Outcome 5 Heavy drinkers at 12 months..................................... 219 Analysis 2.6. Comparison 2 Extended intervention versus minimal or no intervention, Outcome 6 Binge drinkers at 12 months..................................... 219 Analysis 2.7. Comparison 2 Extended intervention versus minimal or no intervention, Outcome 7 Laboratory markers - GGT(IU/L)at12months. 220 Analysis 3.1. Comparison 3 Extended versus brief intervention, Outcome 1 Quantity of drinking (g/week) at 12 months..................................... 221 Analysis 3.2. Comparison 3 Extended versus brief intervention, Outcome 2 Quantity of drinking (g/week) at 12 months, with imputation of unknown standard deviations. ............ 222 Analysis 3.3. Comparison 3 Extended versus brief intervention, Outcome 3 Frequency of drinking (number days drinking/week)at12months. 222 Analysis 3.4. Comparison 3 Extended versus brief intervention, Outcome 4 Intensity of drinking (g/drinking day). 223 Analysis 3.5. Comparison 3 Extended versus brief intervention, Outcome 5 Binge drinkers at 12 months. 224 Analysis 3.6. Comparison 3 Extended versus brief intervention, Outcome 6 Laboratory markers - MCV (fl) at 12 months..................................... 225 ADDITIONALTABLES. 225 APPENDICES ..................................... 230 FEEDBACK...................................... 240 WHAT’SNEW..................................... 244 HISTORY......................................
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