1 Title 1 Neolithic and Medieval Virus Genomes Reveal Complex Evolution
1 Title 2 Neolithic and Medieval virus genomes reveal complex evolution of Hepatitis B 3 4 Authors 5 Ben Krause-Kyora1,2,†*, Julian Susat1*, Felix M. Key2, Denise Kühnert3,2, Esther Bosse1,4, 6 Alexander Immel1,2, Christoph Rinne5, Sabin-Christin Kornell1, Diego Yepes4, Sören 7 Franzenburg1, Henrike O. Heyne6, Thomas Meier7, Sandra Lösch8, Harald Meller9, Susanne 8 Friederich9, Nicole Nicklisch9,10, Kurt Werner Alt9,10,11,12, Stefan Schreiber1,13, Andreas 9 Tholey4, Alexander Herbig2, Almut Nebel1, Johannes Krause2,† 10 11 Affiliations 12 1Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany. 13 2Max Planck Institute for the Science of Human History, Jena, Germany. 14 3Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, 15 Switzerland 16 4Systematic Proteomics & Bioanalytics, Institute for Experimental Medicine, Kiel University, Kiel, 17 Germany. 18 5Institute of Pre- and Protohistoric Archaeology, Kiel University, Kiel, Germany. 19 6Broad Institute, Stanley Center for Psychiatric Research, Cambridge, MA, USA. 20 7Institute for Pre- and Protohistory and Near Eastern Archaeology, Heidelberg University, Heidelberg, 21 Germany. 22 8Department of Physical Anthropology, Institute of Forensic Medicine, University of Bern, Bern, 23 Switzerland. 24 9State Office for Heritage Management and Archaeology Saxony-Anhalt and State Museum of 25 Prehistory, Halle, Germany. 26 10Danube Private University, Krems, Austria. 27 11Department of Biomedical Engineering, University Hospital Basel,
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