Award-Winning Research (PDF)

Total Page：16

File Type：pdf, Size：1020Kb

Award-Winning Research Kyoto University is acknowledged as one of the most accomplished research-oriented universities in Asia. That reputation is testified by the accolades conferred on our alumni and researchers, most notably nine Nobel Prize laureates who undertook vital research during their time at the university. In addition to those awards, several other Kyoto University faculty members have received major accolades, including two Fields Medalists and one Gauss Prize winner. Nobel Prize 1949, Physics 1965, Physics 1981, Chemistry 1987, Physiology and Medicine 2001, Chemistry Hideki Yukawa Shinichiro Tomonaga Kenichi Fukui Susumu Tonegawa Ryoji Noyori 2008, Physics 2008, Physics 2012, Physiology or Medicine 2014, Physics Makoto Kobayashi Toshihide Maskawa Shinya Yamanaka Isamu Akasaki Fields Medal Gauss Prize Kyoto Prize 1970, Mathematics 1990, Mathematics 2006, Mathematics 1995, Basic Sciences 1998, Basic Sciences 2004, Advanced Technology 2010, Advanced Technology Heisuke Hironaka Shigefumi Mori Kiyoshi Ito Chushiro Hayashi Kiyoshi Ito Alan Curtis Kay Shinya Yamanaka Japan Prize Lasker Award 2005, Information and 2005, Cell Biology 1987, Basic Medical 1989, Basic Medical 1998, Basic Medical 2009, Basic Medical 2014, Basic Medical Media Technology Masatoshi Takeichi Research Research Research Research Research Makoto Nagao Susumu Tonegawa Yasutomi Nishizuka Yoshio Masui Shinya Yamanaka Kazutoshi Mori *photos provided by the Japan Prize Foundation Professor Kazutoshi Mori wins the 2014 Albert Lasker Award for Basic Medical Research Professor Kazutoshi Mori of Kyoto University’s Graduate school of Science received the 2014 Albert Lasker Basic Medical Research Award in New York City on September 19. Professor Mori shares the award with Prof. Peter Walter of the University of California, San Francisco. The Two scientists received the award for their “discoveries concerning the unfolded protein response (UPR)—an intracellular quality-control system that detects harmful misfolded proteins in the endoplasmic reticulum and signals the nucleus to carry out corrective measures.” Kyoto University AT A GLANCE 2015 9.

Copy Link

Recommended publications

Looking at Earth: an Astronaut's Journey Induction Ceremony 2017
american academy of arts & sciences winter 2018 www.amacad.org Bulletin vol. lxxi, no. 2 Induction Ceremony 2017 Class Speakers: Jane Mayer, Ursula Burns, James P. Allison, Heather K. Gerken, and Gerald Chan Annual David M. Rubenstein Lecture Looking at Earth: An Astronaut’s Journey David M. Rubenstein and Kathryn D. Sullivan ALSO: How Are Humans Different from Other Great Apes?–Ajit Varki, Pascal Gagneux, and Fred H. Gage Advancing Higher Education in America–Monica Lozano, Robert J. Birgeneau, Bob Jacobsen, and Michael S. McPherson Redistricting and Representation–Patti B. Saris, Gary King, Jamal Greene, and Moon Duchin noteworthy Select Prizes and Andrea Bertozzi (University of James R. Downing (St. Jude Chil- Barbara Grosz (Harvard Univer- California, Los Angeles) was se- dren’s Research Hospital) was sity) is the recipient of the Life- Awards to Members lected as a 2017 Simons Investi- awarded the 2017 E. Donnall time Achievement Award of the gator by the Simons Foundation. Thomas Lecture and Prize by the Association for Computational American Society of Hematology. Linguistics. Nobel Prize in Chemistry, Clara D. Bloomfield (Ohio State 2017 University) is the recipient of the Carol Dweck (Stanford Univer- Christopher Hacon (University 2017 Robert A. Kyle Award for sity) was awarded the inaugural of Utah) was awarded the Break- Joachim Frank (Columbia Univer- Outstanding Clinician-Scientist, Yidan Prize. through Prize in Mathematics. sity) presented by the Mayo Clinic Di- vision of Hematology. Felton Earls (Harvard Univer- Naomi Halas (Rice University) sity) is the recipient of the 2018 was awarded the 2018 Julius Ed- Nobel Prize in Economic Emmanuel J.
[Show full text]
Pnas11141toc 3..7
October 14, 2014 u vol. 111 u no. 41 u 14637–14960 Cover image: Pictured is a duck during feeding. Ducks and other tactile foraging birds rely on their sense of touch, rather than sight, to feed in murky water. Eve R. Schneider et al. found that the trigeminal ganglia in duck bills contain a high number of neurons hypersensitive to mechanical stimuli. Multiplication of mechanosensitive neurons, however, may reduce the number of thermosensitive neurons. This tradeoff may confer an advantage on tactile foraging birds, which can tolerate cold water temperatures without diminishing feeding efficiency. See the article by Schneider et al. on pages 14941–14946. Image courtesy of Eve R. Schneider (Bagriantsev Lab). From the Cover 14941 Duckbill mechanosensitivity 14675 Mobility of packaged viral DNA 14740 Strong male bonds among Guinea baboons 14822 Losing independence in microbial mutualism 14864 Density-based sickle cell detection E4288 Reply to Azuaje: Predicting effective combined Contents therapies for heterogeneous tumors Boyang Zhao, Michael T. Hemann, and Douglas A. Lauffenburger THIS WEEK IN PNAS INNER WORKINGS—An over-the-shoulder look at scientists at work 14637 In This Issue 14639 Inner Workings: Coding on the big screen Robert Frederick LETTERS (ONLINE ONLY) QNAS E4284 Delphi: Somewhere between Scylla and Charybdis? Fergus Bolger and Gene Rowe 14640 QnAs with Alan Guth E4285 Are Marine Group II Euryarchaeota significant Paul Gabrielsen contributors to tetraether lipids in the ocean? Stefan Schouten, Laura Villanueva, Ellen C. Hopmans, Marcel T. J. van der Meer, and Jaap S. Sinninghe Damsté RETROSPECTIVE E4286 Reply to Schouten et al.: Marine Group II planktonic Euryarchaeota are significant contributors to tetraether lipids in the ocean 14641 Jake MacMillan: A pioneering chemist in Sara A.
[Show full text]
Professor Peter Goldreich Member of the Board of Adjudicators Chairman of the Selection Committee for the Prize in Astronomy
The Shaw Prize The Shaw Prize is an international award to honour individuals who are currently active in their respective fields and who have recently achieved distinguished and significant advances, who have made outstanding contributions in academic and scientific research or applications, or who in other domains have achieved excellence. The award is dedicated to furthering societal progress, enhancing quality of life, and enriching humanity’s spiritual civilization. Preference is to be given to individuals whose significant work was recently achieved and who are currently active in their respective fields. Founder's Biographical Note The Shaw Prize was established under the auspices of Mr Run Run Shaw. Mr Shaw, born in China in 1907, was a native of Ningbo County, Zhejiang Province. He joined his brother’s film company in China in the 1920s. During the 1950s he founded the film company Shaw Brothers (HK) Limited in Hong Kong. He was one of the founding members of Television Broadcasts Limited launched in Hong Kong in 1967. Mr Shaw also founded two charities, The Shaw Foundation Hong Kong and The Sir Run Run Shaw Charitable Trust, both dedicated to the promotion of education, scientific and technological research, medical and welfare services, and culture and the arts. ~ 1 ~ Message from the Chief Executive I warmly congratulate the six Shaw Laureates of 2014. Established in 2002 under the auspices of Mr Run Run Shaw, the Shaw Prize is a highly prestigious recognition of the role that scientists play in shaping the development of a modern world. Since the first award in 2004, 54 leading international scientists have been honoured for their ground-breaking discoveries which have expanded the frontiers of human knowledge and made significant contributions to humankind.
[Show full text]
Kazutoshi Mori and Peter Walter Receive the 2014 Albert Lasker Basic Medical Research Award
Kazutoshi Mori and Peter Walter receive the 2014 Albert Lasker Basic Medical Research Award Corinne L. Williams J Clin Invest. 2014;124(10):4138-4142. https://doi.org/10.1172/JCI78419. News Cells are continuously faced with life-and-death decisions based on their ability to handle stressful situations. One indicator of stress is the accumulation of unfolded proteins within the ER, which induces a transcriptional cascade aimed at increasing the folding capacity of the ER. If the burden is too great and homeostasis cannot be restored, the response shifts from damage control to the induction of apoptotic pathways. This unfolded protein response (UPR) is conserved among all eukaryotes, and dysfunction in this pathway underlies many human diseases, including diabetes and cancer. The 2014 Albert Lasker Basic Medical Research award honors Kazutoshi Mori of Kyoto University and Peter Walter of the UCSF (Figure 1) for their contributions toward unraveling the pathways involved in mediating the complex cellular response to ER stress. A simple question In the 1970s, the identification of a set of proteins that were induced in response to viral transformation set the stage for understanding heat shock-independent cellular stress responses. These particular proteins were constitutively present in cells and notably increased in response to glucose deprivation (1) or agents that block post-translational glycosylation, such as tunicamycin. Based on this apparent glucose-dependent regulation, they became known as glucose-regulated proteins (GRPs). One
[Show full text]
Masthead (PDF)
Proceedings of the National Academy ofPNAS Sciences of the United States of America www.pnas.org PRESIDENT OF Cellular and Geology Peter K. Vogt THE ACADEMY Developmental Biology W. G. Ernst Thomas E. Wellems Ralph J. Cicerone Eric H. Davidson James P. Kennett John B. Gurdon Physics EDITOR-IN-CHIEF Eric N. Olson Human Environmental Anthony Leggett Randy Schekman Michael Rosbash Sciences Paul C. Martin David D. Sabatini Susan Hanson Jose´ N. Onuchic ASSOCIATE EDITORS Gertrud M. Schu¨pbach Immunology Physiology and William C. Clark Robert Tjian Alan Fersht Peter Cresswell Pharmacology Douglas T. Fearon Susan G. Amara Jack Halpern Cellular and Molecular Jeremy A. Sabloff Tak Wah Mak David Julius Neuroscience William E. Paul Ramon Latorre Solomon H. Snyder Pietro V. De Camilli Susan R. Wessler Ralph M. Steinman Richard L. Huganir Plant Biology L. L. Iversen Mathematics Anthony R. Cashmore Jeremy Nathans Richard V. Kadison Maarten J. Chrispeels EDITORIAL BOARD Charles F. Stevens Robion C. Kirby Enrico Coen Thomas C. Su¨dhof Jeffery L. Dangl Animal, Nutritional, and Joseph S. Takahashi Medical Genetics, Joseph R. Ecker Applied Microbial Sciences Hans Thoenen Hematology, and Robert Haselkorn David L. Denlinger Charles S. Zuker Oncology R. Michael Roberts Joseph L. Goldstein Plant, Soil, and Linda J. Saif Chemistry Mark T. Groudine Microbial Sciences Ryuzo Yanagimachi Stephen J. Benkovic Tony Hunter Roger N. Beachy Philip W. Majerus Brian J. Staskawicz Anthropology Harry B. Gray David C. Page M. S. Swaminathan Dolores R. Piperno Raphael D. Levine Stanley B. Prusiner Jerrold Meinwald Alan Walker Craig B. Thompson Psychology Mark A. Ratner Inder M.
[Show full text]
Special Edition: Woman Researchers in Kyoto University Vol
Kyoto University Kyoto UniversityKyoto Research Activities Vol.4 No.1 June 2014 Special Edition: Woman Researchers in Kyoto University Vol . 4 No.1 June 2014 Vol.4 No.1 June 2014 Contents Message from the President 1 Promoting a Gender-Equal Research Environment About the Special Issue 2 Message to Our Readers Awards & Honors 4 International Recognition of Kyoto University’s Research Introduction 6 Women in University Research Research Frontiers 10 Cutting-Edge Research in Kyoto University Looking Back 18 A Female Student in the Pioneer Days Encourage Women to Research 20 The Tachibana Award Brief History 26 Ten Years of Gender Equality at KU Programs and Services 28 Gender Equality Promotion Center 31 Summary of Kyoto University 32 Author Index Cover: Clock Tower 33 Map and Access ■▶ p.14 Message from the President Message from the President Promoting a Gender-Equal Research Environment HE NUMBER and ratio of female scholars engaged in research at universities in Japan still remains remarkably T low compared to many other countries. This highlights an area of Japan’s academic environment and system in which there is still plenty of room for improvement. Despite this, however, it is also true that there are many female Japanese scientists who are internationally recognized as outstanding in their fields. It is all the more vital, therefore, to create an environment in which they can fully exercise their capabilities and flourish. To this end, Kyoto University is focusing its efforts on developing a research environment in which all scholars can fully and freely pursue their research regardless of gender.
[Show full text]
Table of Contents (PDF)
April 21, 2015 u vol. 112 u no. 16 u 4833–5254 Cover image: Pictured are marine fossils from a Late Ordovician seafloor uncovered in southwestern Ohio, including a dozen species of brachiopods (large shell in lower right, 1 cm wide), crinoids, and trilobites—three groups that were mainstays of Paleozoic biota but are obscure or absent in modern seas—as well as bryozoans and ostracods. These invertebrates were likely buried during a hurricane, which struck a shallow trop- ical sea that covered most of North America nearly 450 million years ago, leaving behind a rich fossil record that has supported a wide range of evolutionary and ecolog- ical analyses. David Jablonski and Neil H. Shubin introduce the Future of the Fossil Record Special Feature, which describes advances in understanding the origin and evolution of life that emerge from the intersection of paleontology with diverse natural sciences disciplines. See the Introduction to the Special Feature by Jablonski and Shubin on pages 4852–4858. Image courtesy of Steven M. Holland (University of Georgia, Athens, GA). From the Cover 4852 Paleontology, origins, and evolution E2004 Contact between intracellular membranes E2102 Human sex ratio from conception to birth 4952 Probing supercooled liquids Contents CORE CONCEPTS—A brief introduction to emerging topics in science 4835 Core Concept: Capturing atoms in motion Danielle Venton THIS WEEK IN PNAS 4833 In This Issue COMMENTARIES LETTERS (ONLINE ONLY) 4837 Extended synaptotagmins (E-Syts): Architecture and dynamics of membrane contact sites revealed E1968 LQT1-phenotypes in hiPSC: Are we measuring the Ángel Pérez-Lara and Reinhard Jahn right thing? See companion article on page E2004 Torsten Christ, András Horvath, and Thomas Eschenhagen 4839 The human prenatal sex ratio: A major surprise E1969 Reply to Christ et al.: LQT1 and JLNS phenotypes in Steven N.
[Show full text]
Molecular and Cellular Biology Volume 8 May 1988 Number 5
MOLECULAR AND CELLULAR BIOLOGY VOLUME 8 MAY 1988 NUMBER 5 Aaron J. Shatkin, Editor in Chief(1990) Randy W. Schekman, Editor Joan A. Steitz, Editor (1990) Center for Advanced (1992) Yale University Biotechnology and Medicine University of California New Haven, Conn. Piscataway, N.J. Berkeley Robert Tjian, Editor (1991) David J. L. Luck, Editor (1992) Louis Siminovitch, Editor (1990) University of California Rockefeller University Mount Sinai Hospital Berkeley New York, N.Y. Toronto, Canada Harold E. Varmus, Editor (1989) Steven L. McKnight, Editor (1992) University of California Carnegie Institution of Washington San Francisco Baltimore, Md. EDITORIAL BOARD Frederick W. Alt (1990) Michael Green (1988) Douglas Lowy (1990) Matthew P. Scott (1989) Susan Berget (1990) Jack F. Greenblatt (1988) Paul T. Magee (1988) Fred Sherman (1988) Arnold J. Berk (1988) Leonard P. Guarente (1988) James Manley (1989) Arthur Skoultchi (1988) Alan Bernstein (1990) Christine Guthrie (1989) Janet E. Mertz (1990) Barbara Sollner-Webb (1989) Barbara K. Birshtein (1990) James E. Haber (1990) Robert L. Metzenberg (1988) Frank Solomon (1988) J. Michael Bishop (1990) Hidesaburo Hanafusa (1989) Robert K. Mortimer (1988) Karen Sprague (1989) Michael R. Botchan (1990) Leland D. Hartwell (1990) Bernardo Nadal-Ginard (1990) Pamela Stanley (1988) David Botstein (1990) Ari Helenius (1990) Paul Neiman (1989) Nat Sternberg (1989) Bruce P. Brandhorst (1990) Ira Herskowitz (1990) Joseph R. Nevins (1990) Bruce Stiliman (1988) James R. Broach (1988) James B. Hicks (1989) Carol Newlon (1988) Kevin Struhl (1989) Joan Brugge (1988) Alan Hinnebusch (1988) Mary Ann Osley (1990) Bill Sugden (1988) Mario R. Capecchi (1990) Michael J. Holland (1990) Brad Ozanne (1989) Lawrence H.
[Show full text]
Peter Walter “Since All of Our New Knowledge Is Built on Exist- Awarded the Nobel Prize in Chemistry in 1999
ASCB Profile Peter Walter “Since all of our new knowledge is built on exist- awarded the Nobel Prize in Chemistry in 1999. ing knowledge, we need to have full access to the Blobel’s signal hypothesis postulated a protein- scientific literature to do our jobs as scientists,” conducting channel that is made up of protein says Peter Walter. “The knowledge base of man- subunits that attached polypeptide “addresses” to kind is a global resource that belongs to the citi- target proteins to the ER. “This was a large bone zens of the world. It shouldn’t be locked up in the of contention for the next 20 years,” says Blobel, archives of some private publishers who are basi- who served as President of the ASCB in 1990. cally driven by the need to make greater profits.” “But when Peter came, we had the hypothesis. Walter’s passionate views on access to the scien- We had a cell-free system. The question was how tific literature have made him, along with UCSF we get the components of the system.” colleague Keith Yamamoto, a national advocate. Walter had unique skills at the bench and as Their efforts led in 2003 to the organization of a an experimental thinker, says Blobel. “He was boycott of six prestigious scientific journals pub- among the best graduate students I’ve ever had lished by Elsevier. in my lab. He is a very good thinker, supremely Walter's advocacy has made him a momentary well organized logistically, but also willing to take media darling. “At times, I felt like one of those risks.
[Show full text]
Vierzig Jahre Fachverband Atomphysik
DEUTSCHE PHYSIKALISCHE GESELLSCHAFT E.V. Vierzig Jahre Fachverband Atomphysik 1972 - 2012 Herausgegeben von Uwe Becker, Rainer Hentges, Bernd Lohmann, Burkhard Langer Please help us to improve this document by mailing your corrections to Rainer Hentges, Schönhauser Allee 68, 10437 Berlin, [email protected]. In particular it would be nice to get all the names correctly spelled. t Inhalt v06 [ i \ 23. Mai 2013 t Register Vorwort Vor 40 Jahren fanden die ersten Sitzungen des neugegründeten Fachverbands Atomphysik auf der Frühjahrstagung der Deutschen Physikalischen Gesellschaft in Hannover statt. In den davorliegenden Tagungen wurden die Bereiche Atom-, Kern- und Teilchenphysik noch in ge- meinsamen Sitzungen behandelt. Die Gründungsperiode des Fachverbands Atomphysik fand in einer Zeit statt, in der sich das speziﬁsche Fachgebiet in keiner besonders guten Position im Hinblick auf seinen Bei- trag zum Fortschritt der Physik im Allgemeinen befand. Dieser Fortschritt wurde in zuneh- mendem Maße in Fachkreisen mit den faszinierenden Entdeckungen in der Hochenergie- Physik gleichgesetzt. Dass Atomphysik in der breiteren Öffentlichkeit immer noch als Syn- onym für Atom-, Kern- und Elementarteilchenphysik stand, der Titel eines Buches meines Doktorvaters Hans Bucka, ein Schüler von Hans Kopfermann, war in Fachkreisen längst ver- gessen und das Gesamtgebiet in seine jeweiligen Unterdisziplinen aufgeteilt. Hier stand die Hochenergie-Physik, welche die klassische Kernphysik bereits in atemberaubendem Tempo überholt hatte, eineindeutig als Speerspitze der Physik im Vordergrund des Interesses. Es war eine Zeit, in der ich mich manchmal entschuldigen musste, meine Doktorarbeit noch auf ei- nem Gebiet durchzuführen, von dem viele meinten, dies sei doch die „Physik der Frühphase der Quantenphysik“ also die Physik der zwanziger Jahre.
[Show full text]
Lasker Interactive Research Nom'18.Indd
THE 2018 LASKER MEDICAL RESEARCH AWARDS Nomination Packet albert and mary lasker foundation November 1, 2017 Greetings: On behalf of the Albert and Mary Lasker Foundation, I invite you to submit a nomination for the 2018 Lasker Medical Research Awards. Since 1945, the Lasker Awards have recognized the contributions of scientists, physicians, and public citizens who have made major advances in the understanding, diagnosis, treatment, cure, and prevention of disease. The Medical Research Awards will be offered in three categories in 2018: Basic Research, Clinical Research, and Special Achievement. The Lasker Foundation seeks nominations of outstanding scientists; nominations of women and minorities are encouraged. Nominations that have been made in previous years are not automatically reconsidered. Please see the Nomination Requirements section of this booklet for instructions on updating and resubmitting a nomination. The Foundation accepts electronic submissions. For information on submitting an electronic nomination, please visit www.laskerfoundation.org. Lasker Awards often presage future recognition of the Nobel committee, and they have become known popularly as “America’s Nobels.” Eighty-seven Lasker laureates have received the Nobel Prize, including 40 in the last three decades. Additional information on the Awards Program and on Lasker laureates can be found on our website, www.laskerfoundation.org. A distinguished panel of jurors will select the scientists to be honored with Lasker Medical Research Awards. The 2018 Awards will
[Show full text]
NAM Annual Report 2019
2019 Annual Report CONTENTS Special Insert: Responding to the COVID-19 Pandemic 3 Letter from the President 5 2019–2020 Governing Council 7 Organizational Chart 8 The IOM/NAM 50th Anniversary Celebration 9 Program Highlights 10 Responding to Critical & Pressing Issues Confronting the U.S. Opioid Epidemic, 11 Promoting Clinician Well-Being & Resilience, 13 Human Germline Genome Editing, 15 Climate Change & Human Health, 16 Advising the Nation & the World on Health & Health Care Advancing Health Equity, 17 Artificial Intelligence in Health Care, 19 Understanding Heterogeneous Treatment Effects, 20 Vital Directions in Health & Health Care, 21 The Future of Nursing, 22 Leading & Inspiring for the Future Healthy Longevity Global Grand Challenge, 23 Committee on Emerging Science, Technology, & Innovation, 25 Member Highlights 26 Inaugural Election of NAM Officers, 27 Members Inducted in 2019 (Class of 2018), 28 Members Elected in 2019 (Class of 2019), 30 2019 Nobel Laureates, 33 2019 Annual Meeting, 34 In Memoriam, 36 Fellowships & Leadership Programs 37 Awards 42 Finances 47 Donor Appreciation 48 Contact Us 65 2 SPECIAL INSERT Responding to the COVID-19 Pandemic As this document entered its final stages of production, coronavirus disease (COVID-19) began to spread around the world—quickly becoming the most destructive pandemic in a century. The National Academy of Medicine quickly initiated a short-term reorientation of its existing programs to respond to the diverse and far-reaching health impacts of the pandemic, including in the areas of equity, workforce, aging, vulnerable populations, health system strengthening, and scientific and technological innovation. An “impact map” that guides the NAM’s role and priorities with regard to the COVID-19 response appears below.
[Show full text]