Acknowledgment of Reviewers, 2016
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Infection and Immunity
INFECTION AND IMMUNITY VOLUME 56 0 JANUARY 1988 0 NUMBER 1 J. W. Shands, Jr., Editor in Chief Dexter H. Howard, Editor (1991) (1989) University of California University ofFlorida, Gainesville Peter F. Bonventre, Editor (1989) Los Angeles, Calif. Phillip J. Baker, Editor (1990) University of Cincinnati Stephen H. Leppla, Editor (1991) National Institute ofAllergy and Cincinnati, Ohio U.S. Army Medical Research Institute Infectious Diseases Roy Curtiss III, Editor (1990) of Infectious Diseases Bethesda, Md. Washington University Frederick, Md. Edwin H. Beachey, Editor (1988) St. Louis, Mo. Stephan E. Mergenhagen, Editor (1989) VA Medical Center National Institute ofDental Research Memphis, Tenn. Bethesda, Md. EDITORIAL BOARD Julia Albright (1989) Stanley Falkow (1988) Jerry R. McGhee (1988) Charles F. Schachtele (1988) Leonard t. Altman (1989) Joseph Ferretti (1989) Floyd C. McIntire (1988) Julius Schachter (1989) Michael A. Apicella (1988) Richard A. Finkelstein (1989) John Mekalanos (1989) Patrick Schlievert (1990) Neil R. Baker (1989) Vincent A. Fischetti (1989) Jiri Mestecky (1989) June R. Scott (1990) Alan Barbour (1989) David FitzGerald (1989) Suzanne M. Michalek (1989) Philip Scott (1988) John B. Bartlett (1988) Robert Fitzgerald (1989) David C. Morrison (1989) Gerald D. Shockman (1989) Joel B. Baseman (1988) James D. Folds (1988) Steven Mosely (1990) W. A. Simpson (1988) Robert E. Baughn (1990) Peter Gemski (1988) Antony J. Mukkada (1990) Phillip D. Smith (1988) Gary K. Best (1988) Robert Genco (1988) Robert S. Munford (1989) Ralph Snyderman (1988) Jenefer Blackwell (1988) Ronald J. Gibbons (1988) Juneann W. Murphy (1990) Maggie So (1989) Arnold S. Bleiweis (1990) Jon Goguen (1989) H. Nikaido (1989) P. Frederick Sparling (1990) William H. -
The Canadian Society of Biochemistry and Molecular & Cellular Biology
Bulletin The Canadian Society of Biochemistry and Molecular & Cellular Biology/ La Société canadienne de biochimie et de biologie moléculaire et cellulaire 2001 www.csbmcb.ca ISSN 1197-6578/2001 COVER PHOTO: A schematic diagram of the Sec dependent protein translocation system [from The 2001 Merck Frosst Prize Award Address Mark Paetzel and Natalie C. J. Strynadka] Contents CSBMCB Board for 2001-2002 ....................................................................................... 4 CSBMCB President’s Report ............................................................................................ 5 Incoming Members of CSBMCB Executive Board 2001-2002 ......................................... 6 IUBMB Toronto Congress Update ................................................................................. 13 Minutes of the 44th CSBMCB Annual General Meeting ................................................ 14 11th Winternational Symposium .................................................................................. 21 44th Annual Meeting of the CSBMCB .......................................................................... 22 Society Awards 2000-2001 ........................................................................................... 27 Workshop On: Myelin Structure And Its Role In Autoimmunity ..................................... 31 Report on the AUUBC................................................................................................... 34 In Memoriam Peter Dolphin .......................................................................................................... -
Sir Richard Doll, Epidemiologist – a Personal Reminiscence with a Selected Bibliography
British Journal of Cancer (2005) 93, 963 – 966 & 2005 Cancer Research UK All rights reserved 0007 – 0920/05 $30.00 www.bjcancer.com Obituary Sir Richard Doll, epidemiologist – a personal reminiscence with a selected bibliography The death of Richard Doll on 24 July 2005 at the age of 92 after a short illness ended an extraordinarily productive life in science for which he received widespread recognition, including Fellowship of The Royal Society (1966), Knighthood (1971), Companionship of Honour (1996), and many honorary degrees and prizes. He is unique, however, in having seen both universal acceptance of his work demonstrating smoking as the main cause of the most common fatal cancer in the world and the relative success of strategies to reduce the prevalence of the habit. In 1950, 80% of the men in Britain smoked but this has now declined to less than 30%. Richard Doll qualified in medicine at St Thomas’ Hospital in 1937, but his epidemiological career began after service in the Second World War when he worked with Francis Avery Jones at the Central Middlesex Hospital on occupational factors in the aetiology of peptic ulceration. The completeness of Doll’s tracing of previously surveyed men so impressed Tony Bradford Hill that he offered him a post in the MRC Statistical Research Unit to investigate the causes of lung cancer. For the representations of Percy Stocks (Chief Medical Officer to the Registrar General) and Sir Ernest Kennaway had prevailed against the then commonly held view that the marked rise in lung cancer deaths in Britain since 1900 was due only to improved diagnosis. -
Professor Peter Goldreich Member of the Board of Adjudicators Chairman of the Selection Committee for the Prize in Astronomy
The Shaw Prize The Shaw Prize is an international award to honour individuals who are currently active in their respective fields and who have recently achieved distinguished and significant advances, who have made outstanding contributions in academic and scientific research or applications, or who in other domains have achieved excellence. The award is dedicated to furthering societal progress, enhancing quality of life, and enriching humanity’s spiritual civilization. Preference is to be given to individuals whose significant work was recently achieved and who are currently active in their respective fields. Founder's Biographical Note The Shaw Prize was established under the auspices of Mr Run Run Shaw. Mr Shaw, born in China in 1907, was a native of Ningbo County, Zhejiang Province. He joined his brother’s film company in China in the 1920s. During the 1950s he founded the film company Shaw Brothers (HK) Limited in Hong Kong. He was one of the founding members of Television Broadcasts Limited launched in Hong Kong in 1967. Mr Shaw also founded two charities, The Shaw Foundation Hong Kong and The Sir Run Run Shaw Charitable Trust, both dedicated to the promotion of education, scientific and technological research, medical and welfare services, and culture and the arts. ~ 1 ~ Message from the Chief Executive I warmly congratulate the six Shaw Laureates of 2014. Established in 2002 under the auspices of Mr Run Run Shaw, the Shaw Prize is a highly prestigious recognition of the role that scientists play in shaping the development of a modern world. Since the first award in 2004, 54 leading international scientists have been honoured for their ground-breaking discoveries which have expanded the frontiers of human knowledge and made significant contributions to humankind. -
TRINITY COLLEGE Cambridge Trinity College Cambridge College Trinity Annual Record Annual
2016 TRINITY COLLEGE cambridge trinity college cambridge annual record annual record 2016 Trinity College Cambridge Annual Record 2015–2016 Trinity College Cambridge CB2 1TQ Telephone: 01223 338400 e-mail: [email protected] website: www.trin.cam.ac.uk Contents 5 Editorial 11 Commemoration 12 Chapel Address 15 The Health of the College 18 The Master’s Response on Behalf of the College 25 Alumni Relations & Development 26 Alumni Relations and Associations 37 Dining Privileges 38 Annual Gatherings 39 Alumni Achievements CONTENTS 44 Donations to the College Library 47 College Activities 48 First & Third Trinity Boat Club 53 Field Clubs 71 Students’ Union and Societies 80 College Choir 83 Features 84 Hermes 86 Inside a Pirate’s Cookbook 93 “… Through a Glass Darkly…” 102 Robert Smith, John Harrison, and a College Clock 109 ‘We need to talk about Erskine’ 117 My time as advisor to the BBC’s War and Peace TRINITY ANNUAL RECORD 2016 | 3 123 Fellows, Staff, and Students 124 The Master and Fellows 139 Appointments and Distinctions 141 In Memoriam 155 A Ninetieth Birthday Speech 158 An Eightieth Birthday Speech 167 College Notes 181 The Register 182 In Memoriam 186 Addresses wanted CONTENTS TRINITY ANNUAL RECORD 2016 | 4 Editorial It is with some trepidation that I step into Boyd Hilton’s shoes and take on the editorship of this journal. He managed the transition to ‘glossy’ with flair and panache. As historian of the College and sometime holder of many of its working offices, he also brought a knowledge of its past and an understanding of its mysteries that I am unable to match. -
Kazutoshi Mori and Peter Walter Receive the 2014 Albert Lasker Basic Medical Research Award
Kazutoshi Mori and Peter Walter receive the 2014 Albert Lasker Basic Medical Research Award Corinne L. Williams J Clin Invest. 2014;124(10):4138-4142. https://doi.org/10.1172/JCI78419. News Cells are continuously faced with life-and-death decisions based on their ability to handle stressful situations. One indicator of stress is the accumulation of unfolded proteins within the ER, which induces a transcriptional cascade aimed at increasing the folding capacity of the ER. If the burden is too great and homeostasis cannot be restored, the response shifts from damage control to the induction of apoptotic pathways. This unfolded protein response (UPR) is conserved among all eukaryotes, and dysfunction in this pathway underlies many human diseases, including diabetes and cancer. The 2014 Albert Lasker Basic Medical Research award honors Kazutoshi Mori of Kyoto University and Peter Walter of the UCSF (Figure 1) for their contributions toward unraveling the pathways involved in mediating the complex cellular response to ER stress. A simple question In the 1970s, the identification of a set of proteins that were induced in response to viral transformation set the stage for understanding heat shock-independent cellular stress responses. These particular proteins were constitutively present in cells and notably increased in response to glucose deprivation (1) or agents that block post-translational glycosylation, such as tunicamycin. Based on this apparent glucose-dependent regulation, they became known as glucose-regulated proteins (GRPs). One -
Antimicrobial Resistance and the Role of Vaccines
PROGRAM ON THE GLOBAL DEMOGRAPHY OF AGING AT HARVARD UNIVERSITY Working Paper Series Antimicrobial Resistance and the Role of Vaccines David E. Bloom, Steven Black, David Salisbury, and Rino Rappuoli June 2019 PGDA Working Paper No. 170 http://www.hsph.harvard.edu/pgda/working/ Research reported in this publication was supported in part by the National Institute on Aging of the National Institutes of Health under Award Number P30AG024409. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. SPECIAL FEATURE: INTRODUCTION Antimicrobial resistance and the role of vaccines SPECIAL FEATURE: INTRODUCTION David E. Blooma, Steven Blackb, David Salisburyc, and Rino Rappuolid,e,1 Stanley Falkow (Fig. 1) dedicated his life’s work to being reported (6). These health consequences will the study of bacteria and infectious disease. He have damaging social and economic sequelae, such was a leader in the discovery of the mechanisms as lost productivity due to increased morbidity and of antibiotic resistance and among the first to mortality, and even social distancing, as fear of inter- recognize and raise the alarm about the problem of multidrug resistance. The articles of this Spe- personal contact grows. ’ cial Feature on Antimicrobial Resistance and the Although projections of AMR s future burden Role of Vaccines are dedicated to his memory depend on several assumptions and are therefore (Box 1). uncertain, the idea that the health and economic consequences of AMR will become significant is rea- Rising antimicrobial resistance (AMR) is one of the sonable. In 2014, the Review on Antimicrobial Resis- greatest health challenges the world currently faces. -
Access Pdf of Lancet Paper on Global Burden of Disease Here
Articles A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 Stephen S Lim‡, Theo Vos, Abraham D Flaxman, Goodarz Danaei, Kenji Shibuya, Heather Adair-Rohani*, Markus Amann*, H Ross Anderson*, Kathryn G Andrews*, Martin Aryee*, Charles Atkinson*, Loraine J Bacchus*, Adil N Bahalim*, Kalpana Balakrishnan*, John Balmes*, Suzanne Barker-Collo*, Amanda Baxter*, Michelle L Bell*, Jed D Blore*, Fiona Blyth*, Carissa Bonner*, Guilherme Borges*, Rupert Bourne*, Michel Boussinesq*, Michael Brauer*, Peter Brooks*, Nigel G Bruce*, Bert Brunekreef*, Claire Bryan-Hancock*, Chiara Bucello*, Rachelle Buchbinder*, Fiona Bull*, Richard T Burnett*, Tim E Byers*, Bianca Calabria*, Jonathan Carapetis*, Emily Carnahan*, Zoe Chafe*, Fiona Charlson*, Honglei Chen*, Jian Shen Chen*, Andrew Tai-Ann Cheng*, Jennifer Christine Child*, Aaron Cohen*, K Ellicott Colson*, Benjamin C Cowie*, Sarah Darby*, Susan Darling*, Adrian Davis*, Louisa Degenhardt*, Frank Dentener*, Don C Des Jarlais*, Karen Devries*, Mukesh Dherani*, Eric L Ding*, E Ray Dorsey*, Tim Driscoll*, Karen Edmond*, Suad Eltahir Ali*, Rebecca E Engell*, Patricia J Erwin*, Saman Fahimi*, Gail Falder*, Farshad Farzadfar*, Alize Ferrari*, Mariel M Finucane*, Seth Flaxman*, Francis Gerry R Fowkes*, Greg Freedman*, Michael K Freeman*, Emmanuela Gakidou*, Santu Ghosh*, Edward Giovannucci*, Gerhard Gmel*, Kathryn Graham*, Rebecca Grainger*, Bridget Grant*, -
Physics of Information in Nonequilibrium Systems A
PHYSICS OF INFORMATION IN NONEQUILIBRIUM SYSTEMS A THESIS SUBMITTED TO THE GRADUATE DIVISION OF THE UNIVERSITY OF HAWAI`I AT MANOA¯ IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF DOCTOR OF PHILOSOPHY IN PHYSICS MAY 2019 By Elan Stopnitzky Thesis Committee: Susanne Still, Chairperson Jason Kumar Yuriy Mileyko Xerxes Tata Jeffrey Yepez Copyright c 2019 by Elan Stopnitzky ii To my late grandmother, Rosa Stopnitzky iii ACKNOWLEDGMENTS I thank my wonderful family members Benny, Patrick, Shanee, Windy, and Yaniv for the limitless love and inspiration they have given to me over the years. I thank as well my advisor Susanna Still, who has always put great faith in me and encouraged me to pursue my own research ideas, and who has contributed to this work and influenced me greatly as a scientist; my friend and collaborator Lee Altenberg, whom I have learned countless things from and who contributed significantly to this thesis; and my collaborator Thomas E. Ouldridge, who also made important contributions. Finally, I would like to thank my partner Danelle Gallo, whose kindness and support have been invaluable to me throughout this process. iv ABSTRACT Recent advances in non-equilibrium thermodynamics have begun to reveal the funda- mental physical costs, benefits, and limits to the use of information. As the processing of information is a central feature of biology and human civilization, this opens the door to a physical understanding of a wide range of complex phenomena. I discuss two areas where connections between non-equilibrium physics and information theory lead to new results: inferring the distribution of biologically important molecules on the abiotic early Earth, and the conversion of correlated bits into work. -
Report of Activities 2010 ABN 76 470 896 415
The Royal Society of New South Wales Report of Activities 2010 ABN 76 470 896 415 The Royal Society of New South Wales is one of the oldest learned societies in the southern hemisphere. Its main function is to promote science in all its aspects, and to link the disciplines of science to each other and to other elements of human endeavour. Membership of The Royal Society of New South Wales is open to anyone interested in the pursuit of these ideals. The special category of Student Member encourages science scholarship, especially among the young. THE SOCIETY’S FAMOUS MEMBERS The Clarke Medal Awarded since 1878 for distinguished HISTORY harles Darwin was elected a work in the natural sciences, recipients Cmember of the Royal Society have included Professor Thomas The Royal Society of New South of New Wales in 1879. His letter of Huxley in 1880, Baron Ferdinand von Wales was established as the acceptance to the Society is one of the Müller in 1883, Professor Sir Edgeworth Philosophical Society of Australasia significant items in our collection of David in 1917 and Sir Douglas Mawson on 27 June 1821. Australia’s scientific heritage. in 1936. t was the first scientific society in the Lawrence Hargrave, Australia’s Colony of New South Wales, and was I pioneering flight researcher, was a The Edgeworth David Medal formed ‘with a view to inquiring into member of the Royal Society of New the various branches of physical science This medal has been awarded since of this vast continent [Australia] and its South Wales and published all his 1948 for distinguished contributions to adjacent regions’. -
Phylogenetic Signal in Phonotactics
Phylogenetic signal in phonotactics Jayden L. Macklin-Cordes,1 Claire Bowern2 and Erich R. Round1,3,4 1 The University of Queensland | 2 Yale University | 3 University of Surrey | 4 Max Planck Institute for the Science of Human History Phylogenetic methods have broad potential in linguistics beyond tree infer- ence. Here, we show how a phylogenetic approach opens the possibility of gaining historical insights from entirely new kinds of linguistic data – in this instance, statistical phonotactics. We extract phonotactic data from 112 Pama-Nyungan vocabularies and apply tests for phylogenetic signal, quanti- fying the degree to which the data reflect phylogenetic history. We test three datasets: (1) binary variables recording the presence or absence of biphones (two-segment sequences) in a lexicon (2) frequencies of transitions between segments, and (3) frequencies of transitions between natural sound classes. Australian languages have been characterized as having a high degree of phonotactic homogeneity. Nevertheless, we detect phylogenetic signal in all datasets. Phylogenetic signal is greater in finer-grained frequency data than in binary data, and greatest in natural-class-based data. These results demonstrate the viability of employing a new source of readily extractable data in historical and comparative linguistics. Keywords: historical signal, phylogenetic comparative methods, historical linguistics, phonology, comparative linguistics, linguistic phylogenetics, Pama-Nyungan, Australian languages 1. Introduction A defining methodological -
Quantum Aspects of Life / Editors, Derek Abbott, Paul C.W
Quantum Aspectsof Life P581tp.indd 1 8/18/08 8:42:58 AM This page intentionally left blank foreword by SIR ROGER PENROSE editors Derek Abbott (University of Adelaide, Australia) Paul C. W. Davies (Arizona State University, USAU Arun K. Pati (Institute of Physics, Orissa, India) Imperial College Press ICP P581tp.indd 2 8/18/08 8:42:58 AM Published by Imperial College Press 57 Shelton Street Covent Garden London WC2H 9HE Distributed by World Scientific Publishing Co. Pte. Ltd. 5 Toh Tuck Link, Singapore 596224 USA office: 27 Warren Street, Suite 401-402, Hackensack, NJ 07601 UK office: 57 Shelton Street, Covent Garden, London WC2H 9HE Library of Congress Cataloging-in-Publication Data Quantum aspects of life / editors, Derek Abbott, Paul C.W. Davies, Arun K. Pati ; foreword by Sir Roger Penrose. p. ; cm. Includes bibliographical references and index. ISBN-13: 978-1-84816-253-2 (hardcover : alk. paper) ISBN-10: 1-84816-253-7 (hardcover : alk. paper) ISBN-13: 978-1-84816-267-9 (pbk. : alk. paper) ISBN-10: 1-84816-267-7 (pbk. : alk. paper) 1. Quantum biochemistry. I. Abbott, Derek, 1960– II. Davies, P. C. W. III. Pati, Arun K. [DNLM: 1. Biogenesis. 2. Quantum Theory. 3. Evolution, Molecular. QH 325 Q15 2008] QP517.Q34.Q36 2008 576.8'3--dc22 2008029345 British Library Cataloguing-in-Publication Data A catalogue record for this book is available from the British Library. Photo credit: Abigail P. Abbott for the photo on cover and title page. Copyright © 2008 by Imperial College Press All rights reserved. This book, or parts thereof, may not be reproduced in any form or by any means, electronic or mechanical, including photocopying, recording or any information storage and retrieval system now known or to be invented, without written permission from the Publisher.