1989 APPLICATION FOR FULL MEMBERSHIP IN THE AMERICAN SOCIETY FOR MICROBIOLOGY 1913 I Street, NW * Washington, D.C. 20006 * (202) 833-9680 COMPLETE ALL INFORMATION REQUESTED AND RETURN FORM WITH REMITTANCE IN U.S. FUNDS Eligibility ASM welcomes to full membership anyone who is interested in its objectives and has a minimum of a bachelor's degree or equivalent in microbiology or a related field. Initiation Memberships are initiated and renewed in January each year Unless there are directions to the contrary, membership nomina- tions received prior to September 1 are credited to the current year, and back issues of the selected publications for the current year are furnished, if available. Nominations received after September 1 will become effective the following January. NAME MISSMS. OR. (CIRCLE ONE) MRS. MR. FIRST INITIAL LAST MAIL NAME AS YOU WANT IT TO APPEAR ON YOUR MAILING LABEL ADDRESS WHERE YOU WANT TO RECEIVE YOUR SUBSCRIPTIONS

STATE/PROVINCE ZIP/POSTAL CODE COUNTRY PHONE (OFFICE) ( ) HOME (02) YEAR OF BIRTH SEX. HIGHEST DEGREE SUBJECT AREA YEAR EARNED_ EMPLOYER PRESENT POSITION SIGNATURE OF APPLICANT DATE *NOMINATED BY MEMBER l SIGNATURE OF ASM MEMBER #1 If you are not associated with an ASM nominating member, you can still apply for membership and we will contact you. Member How did you learn about the ASM? (Check one): Information o A colleague El An advertisement in a journal O Presenting a paper at an ASM meeting O A professor O Direct mail inquiry O An ASM Branch O An ASM journal O A workshop, conference or meeting O Student membership in ASM O None of the above Dues Annual dues for 1989 are $65. Dues include ASM News (monthly) and a $43 credit which may be deducted from the total cost of the journal(s) you purchase at the special membership rates indicated below. Journals Please check:

O Enclosed is my dues payment (U.S. dollars only) ...... $65 O Please send me the following ASM journal(s) at Member Price(s): U.S. Non-U.S. Amount Antimicrobial Agents and Chemotherapy ...... $35 . $61...... $ AA Applied and Environmental Microbiology ...... 35 .61...... _ AE Molecular and Cellular Biology ...... 43 .71...... _ CB Clinical Microbiology Reviews...... 16 .32. CM Infection and Immunity ...... 41 .70. IA International Journal of Systematic Bacteriology ...... 35...... 5...... 33 IJ Journal of Bacteriology ...... 41 .71...... _ JB Journal of Clinical Microbiology ...... 35 .61...... _ JC Journal of Virology ...... 41 .71...... _ JV Microbiological Reviews ...... 16 .32...... MR Total Joumal Fees $ - Subtract your $43 Member Journals Credit - $43 Subtotal (if less than zero, enter zero) $ - Add your $65 Membership Dues + $65 Total (Dues plus Journals). If total is less than $65.00, enter $65 $ - PAYMENT IN U.S. DOLLARS MUST ACCOMPANY APPLICATION A membership card, voting registration form, ASM Placement Service information and the journal(s) of your choice will be sent within 90 days upon completion of processing. ASM dues are tax deductible to the extent permitted by law. ASM designates $12 of your dues for ASM News. Rates are for 1989 only. Applicants must remit in U.S. dollars by check or draft payable to ASM through a U.S. bank located within the Continental U.S. Appli- cants from Canada may use check made out in U.S. dollars and drawn on a Canadian bank or applicants may choose to pay with VISA, MasterCard, or American Express. If that is your preference, please fill in the box below. Li VISA # II IEXPIRATION [ MASTERCARD # III I I DATE: Oii AMEX # M TODAYS DATE MONTH DAY YEAR SIGNATURE MINIMUM CHARGE $15.00 | MCB 12/88 MOLECULAR AND CELLULAR BIOLOGY VOLUME 8 * DECEMBER 1988 * NUMBER 12

Aaron J. Shatkin, Editor in Chief (1990) Randy W. Schekman, Editor Robert Tjian, Editor (1991) Center for Advanced (1992) University of California Biotechnology and Medicine University of California Berkeley Piscataway, N.J. Berkeley Alan M. Weiner, Editor (1993) David J. L. Luck, Editor (1992) Louis Siminovitch, Editor (1990) Yale University Rockefeller University Mount Sinai Hospital New Haven, Conn. New York, N.Y. Toronto, Canada Owen- N. Witte, Editor (1993) Steven L. McKnight, Editor (1992) Joan A. Steitz, Editor (1990) Molecular Biology Institute Carnegie Institution of Washington Yale University University of California Baltimore, Md. New Haven, Conn. Los Angeles

EDITORIAL BOARD Frederick W. Alt (1990) Steve Goff (1989) Susan Lindquist (1990) Norman P. Salzman (1988) Susan Berget (1990) Michael Green (1988) Stuart M. Linn (1989) Paul Schedl (1990) Arnold J. Berk (1988) Jack F. Greenblatt (1988) Douglas Lowy (1990) Milton J. Schlesinger (1989) Alan Bernstein (1990) Leonard P. Guarente (1988) Paul T. Magee (1988) Matthew P. Scott (1989) Barbara K. Birshtein (1990) Christine Guthrie (1989) James Manley (1989) Fred Sherman (1988) J. Michael Bishop (1990) James E. Haber (1990) Janet E. Mertz (1990) Arthur Skoultchi (1988) Michael R. Botchan (1990) Hidesaburo Hanafusa (1989) Robert L. Metzenberg (1988) Barbara Sollner-Webb (1989) David Botstein (1990) Leland D. Hartwell (1990) Robert K. Mortimer (1988) Frank Solomon (1988) Bruce P. Brandhorst (1990) Ari Helenius (1990) Bernardo Nadal-Ginard (1990) Karen Sprague (1989) James R. Broach (1988) Ira Herskowitz (1990) Paul Neiman (1989) Pamela Stanley (1988) Joan Brugge (1988) James B. Hicks (1989) Joseph R. Nevins (1990) Nat Sternberg (1989) Mario R. Capecchi (1990) Alan Hinnebusch (1988) Carol Newlon (1988) Bruce Stillman (1988) John A. Carbon (1990) Michael J. Holland (1990) Mary Ann Osley (1990) Kevin Struhl (1989) Marian Carlson (1989) Greg Hoilis (1990) Brad Ozanne (1989) Bill Sugden (1988) C. Thomas Caskey (1990) Anita K. Hopper (1988) Harvey L. Ozer (1988) Lawrence H. Thompson (1988) Lawrence A. Chasin (1988) Peter M. Howley (1988) Mary Lou Pardue (1988) Shirley M. Tilghman (1990) Nam-Hai Chua (1988) Tony Hunter (1989) Ira H. Pastan (1988) Geoffrey Wahl (1989) Don W. Cleveland (1990) Larry Kedes (1988) David Patterson (1988) Peter Walter (1990) Nicholas Cowan (1990) Robert S. Kerbel (1988) Gianni Piperno (1988) Jonathan R. Warner (1990) Elizabeth A. Craig (1988) Daniel Klessig (1989) John R. Pringle (1988) Harold Weintraub (1988) James E. Darnell, Jr. (1988) Barbara Knowles (1989) Jean-Paul Revel (1988) Reed B. Wickner (1988) Mark Davis (1990) Marilyn Kozak (1988) Daniel B. Riflin (1988) Fred Winston (1988) Gideon Dreyfuss (1990) Monty Krieger (1989) G. S. Roeder (1988) Elton T. Young (1990) Mary P. Edmonds (1990) Elizabeth Lacy (1990) Robert G. Roeder (1988) Michael Young (1988) Thomas D. Fox (1990) Alan Lambowitz (1990) Naomi E. Rosenberg (1988) Edward Ziff (1988) Mary-Jane Gething (1990) Arthur D. Levinson (1990) Rodney Rothstein (1990) Helen R. Whiteley, Chairman, Publications Board Kirk Jensen, Director of Publications Linda M. IHig, Managing Editor, Journals Linda M. Illig, Production Editor Molecular and Cellular Biology (ISSN 0270-7306), a publication of the American Society for Microbiology, 1913 I St., N.W., Washington, DC 20006-5107, is devoted to the advancement and dissemination of fundamental knowledge concerning the molecular biology of eucaryotic cells, of both microbial and higher organisms. Instructions to authors are published in the January issue each year; reprints are available from the editors and the Publications Department. The journal is published monthly, one volume per year. The nonmember subscription price is $340 per year; single copies are $30. The member subscription price is $43 (foreign, $63 [air drop shipping]) per year; single copies are $8. Correspondence relating to subscriptions, reprints, defective copies, availability of back issues, lost or late proofs, disposition of submitted manuscripts, and general editorial matters should be directed to the ASM Publications Department, 1913 I St., N.W., Washington, DC 20006-5107 (area 202 833-9680). Claims for missing issues from residents of the United States, Canada, and Mexico must be submitted within 3 months after publication of the issues; residents of all other countries must submit claims within 6 months of publication of the issues. Claims for issues missing because offailure to report an address change or for issues "missing from files" will not be allowed. Second-class postage paid at Washington, DC 20006, and at additional mailing offices. POSTMASTER: Send address changes to Molecular and Cellular Biology, ASM, 1913 I St., N. W., Washington, DC 20006- 5107. Made in the United States of America. Copyright © 1988, American Society for Microbiology. B*: &J L URICr (I'44, All Rights Reserved. The code at the top of the first page of an article in thisjournal indicates the copyright owner's consent that copies of the article may be made for personal use or for personal use of specific clients. This consent is given on the condition, however, that the copier pay the stated per-copy fee through the Copyright Clearance Center Inc., 21 Congress St., Salem, MA 01970, for copying beyond that permitted by Sections 107 and 108 of the U.S. Copyright Law. This consent does not extend to other kinds of copying, such as copying for general distribution, for advertising or promotional purposes, for creating new collective works, or for resale. Author Index

Aaronson, Stuart A., 5570 Furtak, Krystyna, 5150 Lin, Chin, 5521 Ruddle, Frank H., 5280 Abraham, Robert T., 5448 Lin, Ming-Fong, 5477 Rusovick, Karna M., 5448 Acs, George, 5159 Garchon, Henri-Jean, 5459 Lin, Pin-Fang, 5280 Ryffel, Gerhart U., 5323 Amaudruz, Franqoise, 5425 Gardner, Gillian, 5504 Lindell, Christine M., 5100 Anderson, Philip, 5339 Gilfillan, Susan, 5459 Lis, John, 5200 Saez, Lino, 5378 Arai, Ken-ichi, 5410, 5581 Goetsch, Loretta, 5386 Liskay, R. Michael, 5350 Sakiyama, Shigeru, 5561 Arrigo, Andre-Patrick, 5059 Goldman, Emanuel, 5166 Looney, James E., 5268 Sandmeyer, Suzanne B., 5245 Aujame, L., 5486 Goodman, Patricia A., 5528 Lovett, Michael, 5528 Sartor, Carolyn 1., 5310 Goodnow, Christopher C., Lue, Neal F., 5086 Sasaki, Hiroki, 5545 Bailly, Alain, 5323 5459 Sawadaishi, Kazuyuki, 5179 Bandlow, Wolfhard, 5108 Gray, Todd A., 5310 Ma, Chi, 5268 Schlokat, Uwe, 5549 Banerjee, Ranjit, 5159 Gumucio, Deborah L., 5310 MacGregor, Grant R., 5116 Segatto, Oreste, 5570 Banks, Geoffrey R., 5417 Magdolen, Viktor, 5108 Seiki, Motoharu, 5581 Barna, Thomas J., 5448 Hallauer, Patricia L., 5072 Marshall, Susan T., 5528 Sharp, Z. Dave, 5432 Barr, Philip J., 5126 Hamlin, Joyce L., 5268, 5398 Martinson, Harold G., 5369 Snowden, Margaret M., 5331 Barron, Emily A., 5432 Hanafusa, Hidesaburo, 5541 Matsumoto, Kunihiro, 5410 Solter, Davor, 5470 Barth, Carolyn Frisch, 5358 Hansen, Lori J., 5245 McHugh, Kirk M., 5224 Sprague, Karen U., 5504 Baum, Peter, 5386 Hastings, Kenneth E. M., McKean, David J., 5448 Stumph, William E., 5566 Belmont, John W., 5116 5072 Merlie, J. P., 5257 Suhan, Joseph P., 5059 Berg, Leslie J., 5459 Hawkins, Dianne, 5116 Milgrom, Edwin, 5323 Sun, Xiao-Hong, 5200 Beverley, Stephen M., 5188 Heitlinger, Ellen, 5323 Miller, Paul F., 5439 Surdin-Kerjan, Yolande, 5132 Botros, Ihab W., 5566 Hendrick, Joseph P., 5150 Miyatake, Shoichiro, 5581 Jack 5292 Brennwald, Patrick, 5575 Henikoff, Steven, 5206 Moore, Kateri A., 5116 Szostak, W., Buchman, Andrew R., 5086 Hinnebusch, Alan G., 5439 Morinaga, Tomonori, 5179 Byers, Breck, 5386 Hirano, Akiko, 5232 Mueller, Peter P., 5439 Takenaga, Keizo, 5561 Ho, Steffan N., 5448 Muller, Gunter, 5108 Tamaoki, Taiki, 5179 Cao, Zhaodan, 5432 Hopper, Anita K., 5140 Taylor, Benjamin A., 5528 Carlson, George A., 5528 Horz, Wolfram, 5513 Nakamura, Yohko, 5561 Taylor, Susan Y., 5417 Caskey, C. Thomas, 5116 Humphries, Eric H., 5358 Nakayama, Naoki, 5410 Thomas, Dominique, 5132 Cato, Andrew C. B., 5323 Nicolas, Alain, 5292 Tokunaga, Katsuo, 5561 Chalker, Douglas L., 5245 lida, Hidetoshi, 5555 Troutman, W. Brad, 5268 Chang, Steve M.-W., 5116 Isaya, Grazia, 5150 Obinata, Masuo, 5545 Tso, J. Yun, 5200 Clinton, Gail M., 5477 Ivars, Fredrik, 5459 Oechsner, Ulrich, 5108 Tyrrell, Rex M., 5425 Collins, Francis S., 5310 Oishi, Michio, 5545 Company, Mahshid, 5299 Jackson, Belinda M., 5439 Orr-Weaver, Terry L., 5292 Underwood, Douglas C., 5504 Condliffe, Donald P., 5504 Jakobovits, Edward B., 5549 Conway, Edward M., 5588 Jakubowski, Hieronim, 5166 Paulson, K. Eric, 5541 Crowder, C. Michael, 5257 Jameson, J. Larry, 5100 Pavlovic, Branka, 5513 Vannice, James L., 5549 Cummins, Claudia, 5339 Johnson, Daniel H., 5206 Peterson, Alan C., 5072 Vesco, Cesare, 5495 Curran, Tom, 5521 Peterson-Torchia, Marilyn, Villalon, Deborah, 5116 Kageyama, Hajime, 5561 5528 Davis, Mark M., 5459 Kalousek, Frantisek, 5150 Petrillo-Peixoto, Maria L., Wager-Smith, Karen, 5116 Derynck, Rik, 5549 Kaneko-Ishino, Tomoko, 5545 5188 Waildman, Alan S., 5350 Di Fiore, Pier Paolo, 5570 Karpen, Saul, 5159 Pierce, Jacalyn H., 5570 Wang, Shirley S., 5140 Dijkwel, Pieter A., 5398 Keyse, Stephen M., 5425 Ponta, Helmut, 5323 Welch, William J., 5059 Dreesen, Thomas D., 5206 King, C. Richter. 5570 Porter, Gregory, 5575 Westaway, David, 5528 Klein-Hitpass, Ludger, 5323 Pribyl, Thomas M., 5369 Williams, Lewis T., 5126 Errede, Beverly, 5299 Knickerbocker, Heidi, 5504 Price, Peter, 5159 Wise, Jo Ann, 5575 Escobedo, Jaime A., 5126 Korf, Gina M., 5566 Prusiner, Stanley B., 5528 Wong, Timothy, 5232 Kornberg, Roger D., 5086 Wu, Ray, 5200 Faller, Douglas V., 5080 Kornbluth, Sally, 5541 Ramakrishnan, Lalita, 5216 Fazekas de St. Groth, Kume, Tsau Uan, 5545 Rauch, Claudine, 5323 Barbara, 5459 Riordan, Maureen F., 5310 Yeh, Dong-Bor, 5280 Fenton, Wayne A., 5150 Leadon, Steven A., 5331 Rood, Kirsten L., 5310 Yip, Carli, 5386 Firko, H., 5486 Lee, William M. F., 5521 Rosenberg, Leon E., 5150 Yoshida, Mitsuaki, 5581 Fischer-Fantuzzi, Lia, 5495 Lessard, James L., 5224 Rosenberg, Naomi, 5216 Young, Michael W., 5378 Fletcher, Fred A., 5116 Leu, Tzeng-Horng, 5268 Rosenberg, Nathan, 5132 Flintoff, Wayne F., 5268 Levinson, Arthur D., 5549 Rosenberg, Robert D., 5588 Zelent, Arthur, 5159 Fox, Niles, 5470 Lieberman, Howard B., 5280 Rothstein, Rodney, 5132 Zullo, John N., 5080 1989 APPLICATION FOR STUDENT MEMBERSHIP IN THE AMERICAN SOCIETY FOR MICROBIOLOGY 1913 I Street, NW * Washington, D.C. 20006 * (202) 833-9680 COMPLETE ALL INFORMATION REQUESTED AND RETURN FORM WITH REMITTANCE IN U.S. FUNDS Eligibility Any matriculated student majoring in microbiology or a related field who has not earned a doctoral degree is eligible for election as a Student Member. Student Members have all the privileges of membership except the right to vote and hold office in the Society. Student Members receive ASM News monthly and are entitled to subscribe to the Society's scientific journals at member rates. Initiation Memberships are inttiated and renewed in January each year Unless there are directions to the contrary, membership nomina- tions received prior to September 1 are credited to the current year, and back issues of the selected publications for the current year are furnished, if available. Nominations received after September 1 will become effective the following January. NAME MS. (CIRCLE ONE) MRS. MR. FIRST INITIAL LAST MAIL NAME AS YOU WANT IT TO APPEAR ON YOUR MAILING LABEL ADDRESS WHERE YOU WANT TO RECEIVE YOUR SUBSCRIPTIONS

STATE/PROVINCE ZIP/POSTAL CODE COUNTRY PHONE (OFFICE (01) HOME (02) YEAR OF BIRTH SEX HIGHEST DEGREE MAJOR FIELD OF STUDY SCHOOL SIGNATURE OF APPLICANT DATE SIGNATURE OF CHAIRMAN OF MAJOR DEPARTMENT MEMBER #1 I I I I I I I

*NOMINATED BY ______MEMBER #l SIGNATURE OF ASM MEMBER *If your departmental chairman is a member of the ASM, a nominating signature is not required. If you are not associated with an ASM nominating member, you can still send in this member application form and we will contact you. Be sure to include your dues. Member How did you learn about the ASM? (Check one): Information o A colleague O An advertisement in a journal O Presenting a paper at an ASM meeting O A professor [ Direct mail inquiry [U An ASM Branch D An ASM journal O A workshop, conference or meeting C: None of the above Journals Please check: O Enclosed is my dues payment (U.S. dollars only) ...... $10 El Please send me the following ASM journal(s) at Member Price(s): U.S. Non-U.S. Amount Antimicrobial Agents and Chemotherapy ...... $35 . $61...... $ AA Applied and Environmental Microbiology ...... 35 .61...... _ AE Molecular and Cellular Biology ...... 43 .71...... _ CB Clinical Microbiology Reviews ...... 16 .32...... _ CM Infection and Immunity ...... 41 .70...... _ IA International Journal of Systematic Bacteriology ...... 35...... 5...... 33 IJ Journal of Bacteriology ...... 41 .71...... _ JB Journal of Clinical Microbiology ...... 35 .61...... _ JC Journal of Virology ...... 41 .71. JV Microbiological Reviews ...... 16 32 MR Total Journal Fees $ - Aid your $10 Membership Dues + $10 Total $ - PAYMENT IN U.S. DOLLARS MUST ACCOMPANY APPLICATION A membership card and the journal(s) of your choice will be sent within 90 days upon completion of processing. ASM dues are tax deductible to the extent permitted by law. ASM designates $7 of your dues for ASM News. Rates are for 1989 only. Applicants must remit in U.S. dollars by check or draft payable to ASM through a U.S. bank located within the Continental U.S. Applicants from Canada may use check made out in U.S. dollars and drawn on a Canadian bank or applicants may choose to pay with VISA, MasterCard, or American Express. If that is your preference, please fill in the box below. C: VISICA # EXPIRATIO O MASTERCARD # I I I I I I I I I I I I I I I DATE: O AMEX# MO YR TODAYL DATE MONTH DAY YEAR MINIMUM CHARGE $15.00 MCB 12/88 AUTHOR INDEX VOLUME 8

Aaronson, Stuart A., 284, 557, 5570 Baim, Steven B., 1591 Berlin, Vivian, 2411 AB, G., 4557 Bajwa, Wajeeh, 3439 Berlingieri, Maria Teresa, 2261 Abe, Akio, 4991 Baker, Audrey E., 2999 Bernier, Daniel, 1398 Abelson, John, 2379 Baker, Mark D., 4041 Bernstein, Alan, 3143 Abraham, Irene, 4685 Bakker, O., 4557 Bernstein, Mitchell, 4098 Abraham, Robert T., 5448 Balakier, Hanna, 2082 Berrios, Soledad, 1877, 4573 Acs, George, 5159 Balcells, Susana, 1236 Bertness, Virginia, 124 Adams, David E., 2052 Baltimore, David, 234 Besmer, Peter, 4896 Adams, Lonnie D., 4685 Bandlow, Wolfhard, 5108 Betsholtz, Christer, 571, 2753, 3476 Adams, R. L. P., 1443 Banerjee, Ranjit, 5159 Beullens, Monique, 3051 Adams, Sally E., 2989 Banerji, Sunandita S., 3215 Beverley, Stephen M., 5188 Addison, Christine, 3740 Banks, Geoffrey R., 5417 Beyer, Ann L., 2811 Adeniyi-Jones, Samuel, 4433 Bannon, Gary A., 427, 5043 Bhat, Krishnamoorthi, 3251 Adler, Caroline, 2545 Banta, Lois M., 2105, 4936 Bhat, Narayan K., 4700 Aebersold, Ruedi H., 4659 Barker, Kathleen A., 2804 Bibring, Thomas, 2884 Aebi, Markus, 3065 Barna, Thomas J., 5448 Bich-Thuy, Le thi, 511 Ahn, Byung-Yoon, 2442 Bamhart, Kerry M., 3215, 4270 Bigler, Jeannette, 4155 Akhurst, Rosemary J., 2335 Barnstable, Colin J., 1570 Bigner, Sandra H., 3104 Akins, Robert A., 1376 Barr, Philip J., 5126 Billeter, Ruedi, 1361 Akiyama, Tetsu, 1019 Barron, Emily A., 5432 Birnstiel, Max L., 1076 Alamo, Isaac, Jr., 4716 Barta, Andrea, 2011 Birrer, Michael, 186, 3373, 4381 Alavi, Hossain, 3423 Barth, Carolyn Frisch, 5358 Birrer, Michael J., 2668 Alberghina, Lilia, 1345 Bartolomei, Marisa S., 330 Bishayee, Subal, 36% Albrecht, Glenn, 1534 Barton, David, I Bishop, J. D., 3338 Alexandre, Sylvie, 2367 Bartsch, Ingrid, 3891 Bishop, J. Michael, 2435, 4561 Allen, Randy L., 828, 3260 Bascom, Charles C., 3088 Bishop, John O., 4821 Allen-Hoffmann, B. Lynn, 4234 Baserga, Renato, 1551 Blackburn, Elizabeth H., 251 Allen-Nash, Averie, 427 Basilico, Claudio, 2933 Blackhart, Brian D., 71 Allison, Daniel S., 1915 Basson, Michael E., 3797 Blair, Donald G., 923 Allison, Lori A., 321 Bateman, Erik, 747, 1940 Blank, Miri, 1366 Almendral, Jose M., 2140 Bates, Brian, 3487 Blanton, Harriet M., 2257 Alper, Deborah, 3397 Battey, James, 186, 3373, 4381 Blau, H. M., 2295 Al-Shawi, Raya, 4821 Battey, James F., 3129 Blenis, John, 2309 Alt, Frederick W., 1849 Baum, Mary, 754 Blinder, Dmitry, 1957 Altman, Ronni, 3717 Baum, Peter, 5386 Blumberg, Hal, 1868, 4552 Alwine, James C., 1648 Baumann, Heinz, 42 Bobek, Libuse A., 3008 Amaudruz, Francoise, 5425 Bayley, Stanley T., 3955 Boeke, Jef D., 1421, 1432 Amemura, Mitsuko, 267 Bazin, Herve, 441 Boettiger, David, 1414 Amin, Jahanshah, 3761 Becker, Andrew, 2082 Bogenhagen, Daniel F., 2910, 2917 Amson, Robert, 1498 Beemon, Karen, 4858 Bolen, Joseph B., 4353 Amstutz, Hanspeter, 754 Beggs, Jean D., 1067 Bongcam-Rudloff, Erik, 2753 Anagnou, Nicholas P., 4917 Begue, A., 1835 Bonham, Keith, 4469 Ananthan, Jayakumar, 3761 Behra, Renata, 3332 Bookman, Michael A., 4353 Anderson, John N., 2763 Beier, David R., 3864 Boothroyd, John C., 494, 3837 Anderson, Philip, 737, 3748, 5339 Belagaje, Rama, 1715 Boquet, Patrice, 418 Anderson, Robert W., 1253 Belanger, Luc, 1398 Bornstein, Paul, 4851 Andrianopoulos, Alex, 3532 Bell, J. C., 2655 Borrello, Ivan, 557 Andrisani, Ourania M., 1947 Bell, Jeffrey, 91 Botros, Ihab W., 5566 Ansorge, Wilhelm, 4416 Bell, John, 2770 Boucher, Philip, 4510 Antequera, Francisco, 3043 Bell, John B., 1489 Boxer, Linda M., 4110 Apone, Stephen, 4851 Bellot, F., 1970 Boyse, Edward A., 4889 Arai, Ken-ichi, 466, 3777, 5410, 5581 Bellot, Francoise, 1831 Bozzoni, Irene, 4792 Arai, Naoko, 466 Belmont, John W., 5116 Brady, Helen A., 3291 Araki, Hiroyuki, 955 Bemis, Lynne T., 2125 Brandhorst, Bruce B., 3518 Arquint, M., 2655 Ben Amar, Mohamed F., 2166 Brandriss, Marjorie C., 4634 Arrigo, Andre-Patrick, 5059 Benchimol, Samuel, 974 Branton, Philip E., 3955 Arrigo, Salvatore, 4858 Bender, M. A., 1725 Braun, P. E., 2655 Asker, Charlotte, 3168 Benjamin, Thomas L., 2309 Bravo, Rodrigo, 1319, 2140 Atchison, Michael L., 930 Bennett, Randy L., 843 Brenner, Charles, 3556 Benoist, C., 3975 Brennwald, Patrick, 1580, 5575 Atweh, G. F., 5047 Benton, Bret M., 1877 Breslow, Jan L., 2394 Aufderheide, Karl J., 4765 Benz, Edward J., Jr., 1 Bressler, Peter, 867 Aujame, L., 5486 Ber, Rosalie, 2828 Brewer, Alison C., 1301 Austerberry, Charles F., 3947 Berent, E., 2302 Brewer, Gary, 1697 Ausubel, Frederick M., 1985 Berg, David T., 3448 Brickner, H. E., 5047 Avemann, Karin, 3026 Berg, Leslie J., 5459 Brodeur, G. M., 522 Axelson, Hakan, 441 Berg, Paul, 2837, 4395 Broek, Daniel, 2159 Axelson, H'akan, 3168 Berget, Susan M., 814 Bron, Claude, 674 Ayer, Donald E., 2021 Bergsma, Derk J., 241 Brondyk, William H., 2089 Berk, A. J., 1765 Brooks, Burke, 186 Bailly, Alain, 5323 Berk, Arnold J., 3017, 4799 Brown, David T., 4406 ii AUTHOR INDEX MOL. CELL. BIOL.

Brown, Donald D., 1684 Charnay, Patrick, 1319 Cosman, David, 1803 Brown, E. H., 2149 Charron, Maureen J.. 1027 Costa, Robert H., 81, 1055 Brown, Earl G., 273 Chavrier, Phillippe, 1319 Costas, Maria, 3065 Brown, Karen, 4896 Cheah, Marc S. C.. 259 Cottarel, Guillaume, 2523 Brown, Myles, 1380 Chen, I.-T., 4314 Coulombe, Benoit, 3227 Brown, S. J., 4314 Cheng, Karen, 1206 Courtois, Gilles, 2628 Browning, Philip J., 176 Cheng, Seng H., 1736 Coussens, Paul M., 704 Brugge, Joan S., 2465 Chen-Wu, Joan L.-P., 4981 Cowie, Alison, 3122 Brunet, L., 1765 Cherington, Van, 1380 Cox, John V., 1327 Brunet, Lisa J., 4799 Chevrette, Mario, 1398 Cox, Michael M., 3784 Brunner, Amy M., 2229 Chiad6-Piat, Lorendana, 3510 Crabtree, Gerald R., 1715, 2628 Bucher, Elizabeth A., 4134 Chiang, Tsu-Rong, 764 Crankshaw, Carolyn L., 4234 Buchman, Andrew R., 210, 4395, 5086 Childs, Geoffrey, 1842 Crickmore, Anja, 615 Buckler, Alan J., 1371 Chin, Daniel J., 2713 Cross, Frederick R., 4675 Buhler, Jean-Marie, 3997 Chisholm, Rex L., 794 Cross, Sharon L., 945 Buick, R. N., 4243 Chiu, Choi-Ying, 2713 Crowder, C. Michael, 5257 Burch, John B. E., 1123 Cho, Ken, 3136 Crowe, David T., 2070 Burckhardt, Jean, 2140 Chodosh, Lewis A., 2628 Crumm, Emily R., 4685 Burgess, Jeffrey A., 2089 Choffat, Yves, 3332 Cullen, Catherine Ruta, 330 Burgess, Wilson H., 1831 Choi, Yongwon, 3382 Cummins, Claudia, 5339 Burke, Joanne, 4821 Chou, Janice Yang, 203 Curatola, Anna Maria, 2933 Burkhardt, Anne L., 4071 Christianson, Thomas W., 4502 Curcio, M. Joan, 3571 Burland, Timothy G., 1275 Christy, Robert J., 1093 Curran, Tom, 2063, 5521 Burton, Vicky, 3550 Church, J. G., 4243 Cusick, Michael E., 2379 Burton, Zachary F., 1602 Churchill, Mair E. A., 1684 Czarnecka. Eva, 1113 Bush, Mark R., 1715 Ciafre, Silvia, 4792 Buskin, Jean N., 62 Cigan, A. Mark, 2955, 2964 Daar, Ira O., 802 Buss, Janice E., 3960 Cizdziel, Paul E., 1558 Daigneault, Luc, 3227 Buttin, Gerard, 17 Claesson-Welsh, Lena, 3476 Dalton, Stephen, 1247, 4576 Byers, Breck, 5386 Clark, L., 1443 Damewood, G. P., 2288 Bywater, Margaret, 571, 2753 Clark, Michael W., 2379 Dang, Chi V., 4048 Clarke, Catherine F., 1206 Danovich, Robert M., 3272 Caffarelli, Elisa, 4792 Clarke, Louise, 754 Darlington, Gretchen J., 3857 Calame, Kathryn, 2860, 4972 Clarke, Michael F., 884 Darnell, James E., 1055 Caldwell, R. M., 1197 Claus, Toby E., 4642 Darnell, James E., Jr., 81, 4966 Call, Susan M., 3357 Clayson, Edward T., 3391 Darveau, Andre, 2875 Camonis, Jacques H., 2980 Clayton, Christine E., 4055 Dasgupta, Asim, 3175 Campbell, Bruce A., 1993 Clayton, David A., 3496, 4502 Daugherty, Cathie, 1845 Campbell, Linda, 2628 Clements, John M., 4533 Davidson, Richard L., 4185 Canton, Marc, 2082 Clerc, Roger G., 2402 Davies, Peter L., 3670 Cao, Huining, 2869, 3969 Cleveland, Don W., 1224 Davis, Alan H., 4745 Cao, Zhaodan, 5432 Clinton, Gail M., 5477 Davis, Francis C., 4425 Capon, Daniel J., 2555 Co, Man Sung, 273 Davis, Mark M., 5459 Capozza, Michael A., 4547 Coffey, Robert J., Jr., 3088 Davis, Richard E., 4745 Caras, Ingrid W., 2698 Cohen, Donna R., 2063 Davis, Ronald W., 1469, 2184, 4370 Carbon, John, 754 Cohen, Pamela S., 1677 Dean, Neta, 3017 Carleton, Stephen, 3703 Cohen, Roger B., 105 Debatisse, Michelle, 17 Carlin, Cathleen R., 25 Cole, Charles N., 4829 Defeo-Jones, Deborah, 2999 Carlson, George A., 5528 Colgan, John D., 3582 De Greve, Jacques, 186, 4381 Carlson, John R., 2638, 2647 Coll, J.. 1835 DeGreve, Jacques S., 2668 Carrazana, Enrique J., 2267 Collins, Francis S., 5310 Deichaite, Ida, 4295 Carroll, Simon M., 4745 Comb, Michael, 4225 Deininger, Prescott L., 4566 Carroll, Steven L., 241 Comer, Mary B., 4669 Dekel, Itzhak, 1006 Carroll, Susan M., 1525 Comoglio, Paolo M., 1345, 3510 Della Valle, Giuliano, 1336 Casavant, N. Carol, 4669 Compans, Richard W., 3391 Delli-Bovi, Pasquale, 2933 Caskey, C. Thomas, 5116 Company, Mahshid, 2545, 5299 de Mars, Maryellen, 1558 Casson, Lawrence P., 4295 Condliffe, Donald P., 5504 De-Medina, Tali, 2449 Castrillon, Diego, 1432 Condliffe, Donald Peter, 624 Denell, R. E., 4314 Cato. Andrew C. B., 5323 Cone, Roger D., 1036, 3864 Denhez, F., 1835 Catterall, James F., 1160 Coney, Leslie R., 4009 Denis, Clyde L., 2125 Cech, Thomas R., 4450 Connolly, Bernadette, 2342 Denome, Roger M., 4829 Cerami. Contor, L., 2494 Anthony. 2394 Conway. Edward M.. 5588 Der. Channing J., 3960 Cerdan, M. Esperanza, 2275 Conway, Greg, 2884 Dero, Brigitte, 2166 Chaleff, Deborah T., 551 Conzelmann, Andreas, 674 DeRose, Margaret L., 1525 Chalker, Douglas L., 5245 Cook, Paul W., 1449 Derynck, Rik, 3415, 5549 Chamberlain, J. W., 1821 Cooper, Geoffrey M., 2472, 3235 de St. Groth, Barbara Fazekas, 5459 Chandler, Susan H., 1863 Cooper, Jonathan A., 540, 2229, 3560 De Togni, Pietro, 2251 Chang, Steve M.-W., 5116 Copeland. Neal G.. 301 Detremerie, Katrien, 3051 Chang, Tien-Hsien, 2379 Coppel. Ross L., 2664 Devarayalu, Sreelekha, 4851 Chao, Janna, 3717 Coquelet. Helene, 2367 Devaux, Brigitte, 1534 Chao. Moses, 3160 Corden. Jeffry L., 330 Dhar, V., 2149 Chao, Moses V., 2242 Corrick. Catherine M., 2589 Dhar. Veena, 4958 VOL. 8, 1988 AUTHOR INDEX iii

Diamond, Lisa E., 2233 Elder, Paula K., 480 Fornace, Albert J., Jr., 4716 Diaz de la Espina, Susana Moreno, 4700 Elgin, Sarah C. R., 3204 Forney, James D., 251 Dickson, Robert C., 3726 Eliyahu, D., 531 Forsburg, Susan L., 647 Didamo, V. T., 2149 Ellis, Nathan A., 4692 Fortier, Craig, 71 Dietrich, Rosemary C., 2361 Emerson, Charles P., Jr., 4134 Fortugno-Erikson, Donna, 1 Dietz, Thomas J., 3204 Emmons, Scott W., 875 Fotheringham, Scott, 3703 Di Fiore, Pier Paolo, 557, 5570 Emr, Scott D., 2105, 4098, 4936 Fourel, Genevieve, 2628 Dijkwel, Pieter A., 5398 Engel, James Douglas, 4416 Fournier, Maurille J., 3282 DiMaio, Daniel, 4071 Enver, Tariq, 1301, 4917 Fox, Niles, 5470 DiMartino, Jorge F., 1253 Erba, Harry, 1790 Fragapane, Paola, 4792 Dinh, Thanh-Hoai, 2247 Erba, Harry P., 1775 Francke, Uta, 1 Di Renzo, Maria Flavia, 3510 Eriksson, Anders, 3476 French, Brent A., 4587 Distel, Robert J., 996 Errede, Beverly, 2545, 5299 French, Chris L., 480 Dixon, Jack E., 1947 Escobedo, Jaime A., 5126 French, Martha, 1236 Dixon, Kathleen, 2428, 3267, 3943 Etkin, Laurence, 1236 Frenkel, Niza, 3272 Dodd, Jonathan, 3997 Etkin, Sara, 1366 Frey, Alan B., 1206 Donahue, Thomas F., 2955, 2964 Evan, Gerard, 4381 Freytag, Svend O., 1614 Donoghue, Daniel J., 1011 Evans, Elaine, 2628 Friden, Phillip, 2690 Doppler, Wolfgang, 4212 Evans, Marilyn I., 1123 Fried, Howard M., 4328 Dorn, A., 3975 Evans, Mark J., 35 Fried, Mike, 3898 Dornburg, Ralph, 2328 Friedman, Thea M., 1123 Dorner, Andrew J., 4063 Fagrelius, Thomas J., 2442 Friesen, James D., 169 Dornfield, Kenneth J., 2442 Fahl, William E., 2089 Fu, Xin-Yuan, 3582 Dougan, Scott T., 2787 Faktor, Ouriel, 2449 Fuchs, Elaine, 486, 722 Dove, William F., 1275 Falco, Joseph, 557 Fujii-Kuriyama, Yoshiaki, 2581 Dower, Steven K., 3357 Faller, Douglas V., 5080 Fujisawa, Jun-ichi, 466 Downing, James R., 1795, 2419 Fangman, Walton L., 293, 4949 Fujiwara, Jun, 2097 Dozier, C., 1835 Fanning, Ellen, 903 Fujiwara, Shigeyoshi, 3080, 4700 Dreesen, Thomas D., 5206 Fanning, Thomas G., 1385 Fukasawa, Toshio, 4991 Dreyfuss, Gideon, 2237 Fasullo, Michael T., 4370 Fukayama, June, 4904 Driscoll, Catherine E., 996 Feagin, Jean E., 1259 Fukui, Mikiharu, 2651 Driscoll, Monica, 664 Fearon, Kathleen, 3636 Fukui, Yasuhisa, 1816 Drucker, Daniel J., 4877 Fedorko, Joseph, 4381 Fukumoto, Hiroaki, 2604 Dubin, Robert A., 1027 Fehling, H. J., 3975 Fulton, Sandra M., 2989 Dufort, Daniel, 5000 Feig, Daniel I., 4477 Funk, Fred D., 4669 Dull, T. J., 2302 Feig, Larry A., 2472, 3235 Funkenstein, Bruria, 1160 Dumont, J. E., 2494 Feinbaum, Rhonda L., 1985 Furdon, Paul J., 860 Duncan, R., 2705 Feinstein, Sabine, 3094 Furtak, Krystyna, 5150 Dunham, Raymond G., 2722 Felsenstein, Kevin M., 875 Fusco, Alfredo, 2261 Dunn, James, 2082 Feng, Y., 10 Dunn, Joyce K., 923 Fenton, Wayne A., 5150 Gaber, Richard F., 2848 Dunn, R. J., 2655 Feramisco, James R., 1670 Gaiser, J. Christopher, 4143 Durand, David B., 1715 Ferguson, Blair, 3955 Gal, Susannah, 3316 Durbin, Karen J., 4608 Ferguson, Jill, 2484 Gallie, Brenda L., 2082 Durnam, Diane M., 1863 Fero, Matthew L., 4204 Gallo, Gregory J., 1648 Dynan, William S., 2021 Ferracini, Riccardo, 3510 Galloway, Denise A., 4018 Ferrell, James E., Jr., 3603 Galson, Deborah L., 381 Eakle, Kurt A., 4098 Field, Jeffrey, 2159 Ganguly, Subinay, 361 Early, A. E., 3458 Fields, Bernard N., 273 Garber, Richard L., 4143 Eaton, Suzanne, 4972 Fields, Stanley, 551 Garchon, Henri-Jean, 5459 Ebendal, Ted, 452 Filipowicz, Witold, 2042 Garcia, Alonzo D., 1266, 4441 Eckdahl, Todd T., 2763 Filmus, J., 4243 Garcia, Joseph, 3717 Eckhardt, Laurel A., 1932 Findly, R. Craig, 3423 Gardner, Gillian, 5504 Eckhart, Walter, 461 Finer-Moore, Janet, 3797 Garfinkel, David J., 1421, 3571 Eddy, E. M., 828, 3260 Fink, Gerald R., 1432, 2848 Garfinkel, Susan, 105 Eddy, Roger, 1775 Finlay, C. A., 531 Garofalo, Robert S., 1638 Edgell, Marshall H., 4669 Firestone, Gary L., 1449 Garsky, Victor M., 2999 Edwards, A. M., 2655 Firko, H., 5486 Gartler, Stanley M., 4692 Edwards, Caroline P., 1449 Fischer-Fantuzzi, Lia, 5495 Gartside, Cyndy L., 62 Edwards, R. H., 2456 Fishel, Barbara, 754 Garvin, Alex M., 3058 Egan, Cay, 3955 Fisher, Paul A., 1877, 4573 Gasson, Judith, 3432 Ehrlich, Rachel, 695 Fisher, Robert J., 4700 Gasson, Judith C., 1979 Eichinger, Daniel, 1432 Fisher, Robert P., 3496 Gat, Galia, 2828 Eickbush, Thomas H., 114 Fitzpatrick, V. Danial, 321 Gaudray, Patrick, 1525 Eide, David, 737 Flavin, Nora B., 2335 Gay, David A., 1224 Eisen, Arri, 4552 Fletcher, Fred A., 5116 Gaynor, Richard, 3717 Eisen, Harvey, 1352 Fletcher, Garth L., 3670 Gazdar, Adi F., 124 Eisenman, Robert N., 2504, 4155 Flickinger, Thomas W., 4868 Gedamu, Lashitew, 4469 Eisenstadt, J., 1821 Flint, Yehudit Berko, 1366 Geerts, Lieve, 3051 Eisenstein, Richard S., 3183 Flintoff, Wayne F., 5268 Geis, Amy M., 5016 Ek, Bo, 3476 Fodor, Eric, 982 Geliebter, Jan, 4342 Elango, Narayanaswamy, 1709 Fogel, Seymour, 1253 Gelinas, Richard E., 713, 1725 iv AUTHOR INDEX MOL. CELL. BIOL.

Gentry, Larry E., 2229, 4162 Guan, Jun-Lin, 2869 Hegemann, Johannes H., 2523 Gerlinger, P., 3975 Guarente, Leonard, 647, 655 Heichman, Karen A., 1132 Gertler, Frank B., 843, 2713 Gudas, Lorraine J., 3906 Heindl, Lisa M., 3676 Gettner, Sonya N.. 2224 Guerrero, Isabel, 2233 Heintz, Nicholas H., 1923 Getz, Michael J., 480 Guertin, Michel, 1398 Heitlinger, Ellen, 5323 Ghazal, Peter, 1809 Gumucio, D. L.. 1197 Heldin, Carl-Henrik, 2753, 3476 Gianola, Katherine M., 2797 Gumucio, Deborah L., 5310 Heller, Diana L., 2797 Gibbs, Jackson B., 52 Gunning. Peter, 1775 Hellman, Lars, 3526 Giguere, Vincent, 3847 Gurley, William B., 1113 Helmeste, Daiga, 4561 Gilfillan, Susan, 5459 Gustafson, Thomas A., 4110, 4120 Hendershot, Linda M., 4250 Gilinger, Gwen, 1648 Guthrie, Christine, 3150 Hendrick, Joseph P., 5150 Gill, D. Michael, 418 Guyaux, Michel, 2367 Hengstler, Michael, 3298 Gilley, David, 4765 Henikoff, Steven, 5206 Gilmartin, Gregory M., 1076 Habener, Joel F., 4877 Henkemeyer, Mark J., 843 Gilmour, David S., 3204 Haber, James E.. 2342, 3918 Hennighausen, Lothar, 1809 Ginelli, Enrico, 1336 Hadwiger, Jeffrey A.. 2976 Hennis, B. C., 4557 Gingras, Marie-Claude, 1398 Hagen. David C.. 309 Henry, C., 1835 Giordano, Silvia, 3510 Hager, Karl M., 2411 Hensold, Jack O., 2219 Giroux, Craig N., 978 Haggren, Wendy, 1282 Herrero, Juan-Jose, 2042 Givol, D., 1970 Hahn, Mounou, 2659 Herrick, David, 1957 Givol, David, 1498, 1831 Hahn, Steven, 655 Herrup, K., 1821 Glover, Claiborne V. C.. 4981 Hajduk, Stephen L., 4625 Herschman, Harvey R., 4570 Godbout, Roseline, 1169 Halazonetis, Thanos D., 1845 Hershey, John W. B., 993 Goddard, Audrey D., 2082 Halden, Nancy F., 330 Herskowitz, Ira, 1309 Goebl, Mark, 3556 Hallauer, Patricia L., 5072 Hewick, Rodney M., 2933 Goel, Anurag, 2572 Hallberg, Bengt, 1625 Hiai, Hiroshi, 1853 Goetsch, Loretta, 5386 Hallberg, Richard L., 371 Hieter, Philip, 2523 Goldberg, Erwin, 996 Hallbook, Finn, 452 Hilbert, Diana, 1253 Goldberg, Michael L., 615 Haller, Otto, 4518 Hiller, Susanne, 3298 Goldfarb, Mitchell, 3487 Hamada, Hiroshi, 3251 Hinds, P. W., 531 Goldfinger, Naomi, 2078 Hamaguchi, Michinari, 3035 Hinds, Philip W., 1206 Goldman, Emanuel, 5166 Hamil, Katherine G., 4328 Hinnebusch, Alan G., 3827, 4808, 5439 Golomb, Miriam, 3136 Hamlin, Joyce L., 2316, 5268, 5398 Hirai, Hisamaru, 3770 Gong, Zhiyuan, 3518 Hamm, Jorg, 4787 Hirano, Akiko, 5232 Gonzales, Felicidad, 4322 Hammacher, Annet, 2753 Hirano, Toshio, 3546 Gooding, C., 433 Hampe, Annie, 2675 Hirose, Fumiko, 1853 Goodman, Howard M., 4225 Hanafusa, Hidesaburo, 2675, 3035, 5541 Hirota, Yoshiko, 1826 Goodman, Patricia A., 5528 Hanaka, Satoko, 353 Hirschhorn, Joel N., 822 Goodnow, Christopher C., 5459 Hanaoka, Fumio, 347 Hirschman, Jodi E., 4608 Gooley, A. A., 3458 Handa, Hiroshi, 353, 1290 Hiscott, John, 3397 Gorelik, Elieser, 1857 Handel, Laura M., 632 Ho, Steffan N., 5448 Gorman, J. A., 4721 Hane, Bernhard G., 2089 Hodgkin, Jonathan, 3627 Gorman, Robert R., 5052 Hanke, Paul D., 3591 Hoey, Timothy, 4598 Gorovsky, Martin A., 2681, 4780 Hannig, Ernest M., 4808 Hoffmann, F. Michael. 843 Gottesdiener, Keith M., 3809 Hansen, Lori J., 5245 Hofmann, Johann, 4212 Gottesman, Michael M., 3316 Hansen, R. Scott, 4692 Hollingshead, Philip G., 473, 1748 Gottlieb, John, 2513 Hardies, Stephen C., 4669 Hollis, Gregory F., 124 Gould, Kathleen L., 3345 Harrich, David, 3717 Holloman, William K., 3703 Grandori, Carla, 3035 Harrington, Maureen A., 4322 Holm, Kristin, 1580 Granner, Daryl K., 96, 3467 Harris, Alan S., I Holt, Jeffrey T., 963 Graves-Deal, Ramona, 3088 Harshey, Rasika M., 3303 Homa, Fred L., 457 Gray, Todd A., 5310 Hart, Ronald P., 1839 Hopper, Anita K., 5140 Grayson, Dennis R., 81, 1055 Hartley, Janet W., 301 Hopper, James E., 3439 Green, Michael R., 4225 Hartmuth, Klaus, 2011 Horak, Eva M., 4353 Green, Todd L., 1839 Hartshorne, Toinette A., 1868 Horak, Ivan D., 4353 Greenberg, Michael E., 2787 Harvey, Robert W., 1736 Horiguchi, Junko, 3951 Greenberg, Miriam L., 4773 Hashimoto, Shuichi, 3553 Horikoshi, Masami, 4028 Greenblatt, Jack, 1602 Hassell, John A., 5000 Horwich, A. L., 1821 Greenspan, Jeffrey A., 4185 Hastings, Kenneth E. M., 5072 Horwitz, Bruce H., 4071 Greer, Peter A., 578 Horz, Wolfram, 5513 Grichnik, James M., 4587 Hatton, K. S., 2149 Hattori, Seisuke, 4169 Hoshino, Masato, 4169 Grieco, Michele, 2261 Housman, David, 2770 Grinnell, Brian W., 3448 Hauge, Brian M., 2132 Hauschka, Stephen 62 Housman, David E., 381, 2219, 3244 Grob, Rene, 4518 D., Howe, John A., 3955 Grodzicker, Terri, 1036, 3191 Hauser, Janet, 2428, 3267 Howk, R., 1970 Groppi, Vincent E., 5052 Haut, Sheryl R., 1027 Hoy, Pamala, 466 Gros, Philippe, 2770 Hawkins, Dianne, 5116 Hozumi, Nobumichi, 1857 Grosveld, F., 130 Hayatsu, Hikoya, 347 Hruby, D. E., 2456 Grosveld, Frank, 3847 Hayes. Pliny H.. 3670 Hu, Xiaogao, 3487 Groudine, Mark, 3710 Haynes. Joel R., 2419 Huang, Der-Hwa, 1906 Grummt, Ingrid, 3891 Hayward, William S.. 2659 Huang, Li-Chun, 3784 Grundstrom, Thomas, 1625 Heartlein, M. W., 3611 Huang, Ru Chih C., 1093 Grunicke, Hans H.. 4212 Hecht. Norman B., 996, 1748 Hubach, Cynthia A., 5043 VOL . 8, 1988 AUTHOR INDEX v

Hubbell, Susan, 4773 Jones, Nancy H., 3809 Kimura, Sigenobu, 267 Huberman, Joel A., 1408, 4927 Jones, Peter A., 4322 King, C. Richter, 5570 Hug, Hubert, 3065 Judelson, Catherine, 4510 King, Connie S., 540 Hughes, Stephen, 923 June, Carl H., 3820 King, Linda, 2989 Humphries, Eric H., 5358 Kingsman, Alan J., 2989 Hunt, Clayton R., 2925 Kabnick, Karen S., 3244 Kingsman, Susan M., 2989 Hunter, Tony, 3345 Kadesch, Tom, 145 Kingston, Robert E., 353 Huppi, K., 2705 Kageyama, Hajime, 3929, 5561 Kinzler, Kenneth W., 3104 Hutchison, Clyde A., III, 4669 Kakunaga, Takeo, 267 Kirsch, Ilan R., 124 Huxley, Clare, 3898 Kalfayan, Laura J., 1481 Kishimoto, Tadamitsu, 3546 Hwung, Young-Ping, 2070 Kalff, Martha, 2350 Klein, George, 441, 3168 Hyman, Robert, 674 Kalousek, F., 1821 Kleinberger, Tamar, 1366 Hyman, Steven E., 4225 Kalousek, Frantisek, 5150 Klein-Hitpass, Ludger, 5323 Hynes, Michael J., 2589, 3532 Kamino, Hideko, 786 Kliewer, Steven, 3175 Kamiyama, Kiyofumi, 3929 Klionsky, Daniel J., 2105, 4936 Igarashi, Koichi, 588 Kammermeyer, K. Lynn, 778 Kmiecik, Thomas E., 704, 4541 Ihle, James N., 301 Kamps, Mark P., 3969 Knepel, Willhart, 4877 lida, Hidetoshi, 5555 Kanazawa, Susumu, 664 Knezetic, Joseph A., 3114 Ikawa, Shuntaro, 2651 Kanda, Patrick, 2722 Knickerbocker, Heidi, 5504 Imai, Takeshi, 1290 Kane, Caroline M., 4389 Knippers, Rolf, 3026, 3298 Inaguma, Yutaka, 1853 Kane, Susan E., 3316 Knoll, J. H. M., 3611 Ingham, Lynwood D., 4425 Kaneko, Tomoko, 3311 Knott, Timothy J., 571 Ingles, C. James, 321 Kaneko-Ishino, Tomoko, 5545 Knowles, Barbara B., 25 Ingram, Robert S., 1169, 4707 Kanik-Ennulat, Cynthia, 3094 Koch, W., 3975 Ingvarsson, Sigurdur, 3168 Kao, Fa-Ten, 3104 Koeffler, H. Phillip, 3432 Inman, Ross B., 3784 Kaplan, Gerardo, 1103 Kohalmi, Susanne E., 978 Insdorf, Neil F., 2910 Kaplan, Joshua M., 2435 Kohda, Takashi, 2097 Iqbal, Anwar, 4958 Karathanasis, Sotirios K., 605 Kolb, Janet M., 3997 Iqbal, M. A., 2149 Karpen, Saul, 5159 Kole, Ryszard, 860 Isaya, Grazia, 5150 Karpinski, Beverly A., 3809 Koller, Theo, 3026 Isom, Harriet C., 4492 Karrer, Kathleen M., 1664 Kolodrubetz, David, 1282 Israel, Mark A., 1677 Kartasova, Tonja, 2195, 2204 Koltin, Y., 4721 Ito, H., 2295 Kasprzyk, Philip G., 3129 Komro, Cynthia T., 893 Ito, Masamichi, 1236 Katamine, Shigeru, 259 Kondo, Kazunori, 3627 Ivars, Fredrik, 5459 Kato, Jun-ya, 1826 Kondoh, Hisato, 4529 lwane, Makoto, 588 Katoh, Kazuto, 4529 Konieczny, Stephen F., 4134 Katz, Kenneth S., 2779 Koning, Ann, 4510 Jackson, Belinda M., 5439 Katz, Wendy S., 2730 Konishi, Kazuhiko, 2581 Jackson, Stephen P., 1067 Kaufman, Randal J., 4063 Korczak, Bozena, 3143 Jacob, George A., 3114 Kavathas, Paula, 2837 Korf, Gina M., 5566 Jacobson, Allan, 1957, 4088 Kawakita, Masao, 4169 Korn, David, 5016 Jacquet, Michel, 2980 Kawamoto, Takeshi, 267 Kornberg, Roger D., 210, 5086 Jaggi, Rolf, 4212 Kawamoto, Tomoyuki, 1816 Kornbluth, Sally, 5541 Jahng, Kwang-Yeop, 2484 Kaye, Frederic, 186, 2668, 4381 Kornuc, Masayo, 3717 Jakobovits, Aya, 2555 Kayne, Paul, 3717 3777 Kownin, Preecha, 747 Jakobovits, Edward B., 2555, 5549 Kaziro, Yoshito, 3546, Kozak, Marilyn, 2737 Jakobsen, Bent K., 5040 Kedes, Larry, 1775, 1790, 4110,4120 Jakubowski, Hieronim, 5166 Kedinger, Claude, 1534 Kozarsky, Karen F., 3357 Jameson, J. Larry, 5100 Kejzlarova-Lepesant, Jana, 4459 Krane, Maryann G., 4063 Jaramillo, Maria, 1036 Keller, Paul R., 3857 Kraus, Kevin W., 4756 Jarrell, Kevin A., 2361 Kelley, Dawn E., 930 Krebs, Edwin G., 540 Jarvis, Eric E., 309 Kelley, K. A., 1821 Kreider, John W., 4492 Jaskulski, Dariusz, 1551 Kelley, William N., 457 Krieger, Monty, 3357 Jat, Parmjit S., 988 Kelly, Joan M., 2589 Kruse, Fred, 893 Jay, Gilbert, 1857 Kelly, Kathleen, 867 Krystal, Geoffrey, 3373 Jayaram, Makkuni, 3303 Kelly, Sharon L., 4685 Kubli, Eric, 3322, 3332 Jaynes, James B., 62 Kemp, David J., 2664 Kuczmarski, Edward R., 794 Jelsma, Tony N., 3955 Kent, Stephen B., 4659 Kufe, Donald, 340, 3951 Jenkins, John R., 3740 Kerbel, Robert S., 3143 Kukowska, Jolanta, 3683 Jenkins, Nancy A., 301 Kerppola, Tom K., 4389 Kukowska-Latallo, Jolanta F., 884 Jensen, Lee, 3964 Ketter, James S., 1504 Kulesh, David A., 1540 Jepeal, Lisa, 4877 Key, Joe L., I1 13 Kumar, Rakesh, 4289 Jinno, Yoshihiro, 4174 Keyse, Stephen M., 5425 Kumar, Ramesh, 1509 Johnson, A., 1970 Khan, Shabbir, 3696 Kume, Tsau Uan, 5545 Johnson, Alfred C., 4174 Khoury, George, 2984 Kung, Hsing-Jien, 4868 Johnson, Daniel H., 5206 Kile, Jay P., 5043 Kunz, Bernard A., 978 Johnson, Jane E., 62 Kiledjian, Megerditch, 145 Kunze, Michael, 3298 Johnson, Paula A., 1748 Killeen, Marie, 1602 Kuo, C. Frank, 4966 Johnson, Paul J., 4541 Kim, Chul G., 3215, 4270 Kupiec, Martin, 2942 Johnson, T. K., 4314 Kim, Hyeong-Reh Choi, 4416 Kurokawa, Tsutomu, 588 Jones, Carol C., 3260 Kimchi, Adi, 2828 Kusari, Jyotirmoy, 4289 Jones, Cheryl T., 4821 Kimmerly, William J., 210 Kuwano, Michihiko, 4190 vi AUTHOR INDEX MOL. CELL. BIOL.

Lacy, Elizabeth, 2224 Lim, Robert W., 4570 Majumdar, Subrata, 3696 Lagasse, Eric, 2402 Lin, Alice H., 5052 Majumder, Sadhan, 4896 Lai, Eseng, 81 Lin, Chin, 5521 Majzoub, Joseph A., 2267 Lai, Zhi-Chun, 1842 Lin, Ching-Shwun, 160, 4659 Makaroff, Christopher A., 1474 Lam, Cindy, 4773 Lin, Ming-Fong, 5477 Makino, Kozo, 267 Lamarche, Cathy, 3143 Lin, Pin-Fang, 5280 Malim, Michael H., 2989 Lamb, Ned J., 1670 Lin, Young-Sun, 4225 Maly, Karl, 4212 Lamb, Robert A., 1186 Lindell, Christine M., 5100 Manak, John, 4598 Lambowitz, Alan M., 1376 Lindsten, Tullia, 3809, 3820 Maniak, Markus, 153 Lamy, F., 2494 Lindstrom, Yoshie I., 1657 Manley, James L., 3582 Land, M. Catherine, 4204 Ling, Huai-ping, 4295 Mann, Barbara J., 1376 Lanford, Robert E., 2722 Linn, Stuart, 3964 Manning, S. S., 10 Langer, Stephen J., 3872 Linskens, Maarten H. K., 4927 Manoharan, T. Herbert, 2089 LaRosa, Gregory J., 3906 Lioubin, Mario N., 4162 Manos, M. Michele, 5035 LaRue, Helene, 1398 Lipson, Kenneth E., 1551 Manrow, Richard E., 1957, 4088 Latt, S. A., 3611 Lis, John, 5200 Mansukhani, Alka, 615 Latter, Gerald, 1790 Lis, John T., 4727, 4756 Maquat, Lynne E., 802 Lau, Lester F., 3080 Liska, DeAnn J., 4851 Maraia, Richard, 4433 Lauret, Evelyne, 1551 Liskay, R. Michael, 196, 5350 Marchesi, V. T., I Lavi, Sara, 1366 Lissemore, James L., 4840 Mardon, Graeme, 2435 Law, David T. S., 912 Littlejohn, Timothy G., 2589 Margolskee, Robert F., 2837 Law, Martha L., 3104 Littman, Dan R., 2224 Mark, George, 2753 Lax, I., 1970 Liu, J. M., 5047 Marquardt, Hans, 4162 Lax, Irit, 1831 Liu, Ta-Jen, 1887 Marshall, Mark S., 52 Layden, Ronald E., 1352 Livingston, Dennis M., 2442 Marshall, Susan T., 5528 Laz, Thomas M., 4533 Livneh, E., 2302 Marth, Jamey D., 540, 3058 Lazar, Eliane, 1247 Lockshon, Daniel, 4018 Martin, David W., Jr., 2698 Lazarides, Elias, 1327 Lofquist, Alan K., 4441 Martin, G. Steven, 3603 Leadon, Steven A., 5331 Lonberg, Nils, 2224 Martinson, Harold G., 5369 Leary, Susan L., 1160 Looney, James E., 2316, 5268 Martis, Missie Jo, 1979 Leavitt, John, 160, 1790, 4659 Loreni, Fabrizio, 2350 Maru, Yoshiro, 3770 Lebacq, Jean A., 3129 Lossky, Marie, 1067 Marzluf, George A., 1504 Lebacq-Verheyden, Anne-Marie, 3129 Love, Harold D., Jr., 427, 5043 Marzluff, William F., 1887 Le Beau, Michelle M., 722 LoVerde, Philip T., 3008 Masibay, A. S., 2288 Lebkowski, Jane S., 3988 Lovett, Michael, 5528 Mason, Thomas L., 3636, 3647 Lecocq, R., 2494 Lowery, David E., 2610 Mather, Elizabeth L., 1812 Leder, Philip, 1845 Lowry, Charles V., 4651 Mathey-Prevot, Bernard, 234 Lee, Amy S., 4250, 4579 Lowy, D. R., 3565 Mathis, D., 3975 Lee, Frederick, 1236 Lubon, Henryk, 1809 Matoba, Sam, 4904 Lee, Hyunsook, 4727 Lucioli, Alessandra, 4792 Matsuda, Tadashi, 3546 Lee, Inchul, 3382 Lue, Neal F., 5086 Matsumoto, Kunihiro, 3556, 3777, 5410 Lee, Joo Hun, 2280 Luebbers, Robert, 340 Matsuzaki, Hiroaki, 955 Lee, William M. F., 4048, 5521 Luscher, Bernhard, 2504 Mattaj, lain W., 4787 Lee, Younghoon, 4756 Luse, Donal S., 3114 Matthai, R., 2705 Leffak, Michael, 1657 Lusnak, Karin, 1253 Mattison, James, 25 Legrain, P., 3755 Lustig, Arthur J., 2379 Maxson, Rob, 1236 Leiden, Jeffrey M., 3809, 3820 Luttrell, Deirdre K., 497 Mayeda, Akila, 4484 Leinwand, Leslie A., 2797 Luttrell, Louis M., 497 Mayo, Judy K., 4685 Lemaire, Patrick, 1319 Lutzker, Stuart, 1849 Mbonyi, Kaishusha, 3051 Le Meur, M., 3975 Lyons, Sue, 3734 McBurney, Michael W., 406, 3251 Leon, Javier, 786 McCarthy, Brian J., 71 Leong, Jo Ann C., 1748 Ma, Chi, 2316, 5268 McConlogue, Lisa, 764 Leong, K., 1765 MacAuley, Alasdair, 3560 McCormick, J. Justin, 196, 3364 Lepesant, Jean-Antoine, 4459 MacDonald, Barbara, 2159 McCormick, Mary, 2984 Lerch, L. Bernard, 3988 MacDonald, Raymond J., 893 McDougall, James K., 1863 Lerner, Richard A., 2159 Macdonald-Bravo, Heather, 2140 McEntee, Kevin, 1132 Lersch, Robert, 486 MacGregor, Grant R., 5116 McFadden, Grant, 2787 Lessard, James L., 5224 Machida, Cynthia M., 2479 McHugh, Kirk M., 5224 LeStourgeon, Wallace M., 2884 MacLeod, A. R., 433 McIntosh, Evan M., 4616 Leto, Thomas L., I Macnab, J. C. M., 1443 McKay, John, 4851 Leu, Tzeng-Horng, 2316, 5268 McKean, David J., 5448 Levine, A. J., 531 Magdolen, Viktor, 5108 Magee, B. 4721 McLaughlin, Calvin S., 4217 Levine, Arnold J., 1206 B., McMullin, Thomas W., 371 Levine, Arthur S., 3267, 3943 Magee, P. T., 4721 McNally, Maureen M., 3988 Levine, B. Jane, 1887 Mager, Dixie 4958 McNeil, J. Bryan, 1045 Levine, Michael, 4598 Magnuson, Mark A., 96, 3467 Meckling-Hansen, Kelly, 578 Levine, Myron, 457 Maguire, Jean E., 695 Meek, David W., 461 Levinson, Arthur D., 1460, 5549 Magun, Bruce E., 2247, 2479 Meeker, R., 1216 Levy-Wilson, Beatriz, 71 Maher, Pamela A., 564 Mehta, V. B., 3661 Lewin, Alfred S., 2562 Maher, Veronica M., 196, 3364 Meier, Ellen, 4518 Li, Yi, 4362 Maicas, Emmanuel, 169 Meisler, M. H., 1197 Liao, Xiubei, 1580 Maihle, Nita J., 4868 Meisler, Miriam H., 3857 Lieberman, Howard B., 5280 Maisonpierre, Peter C., 4134 Meneveri, Raffaella, 1336 VOL . 8, 1988 AUTHOR INDEX vii

Meng, Yunlian, 4492 Munson, Peter J., 3943 Ono, Mayumi, 4190 Mengel, Lori, 4492 Murphy, Edwin C., Jr., 1558 Orbach, Marc J., 1469, 2211 Menko, A. Sue, 1414 Murphy, Noel B., 2367 Ord, Robin W., 4616 Menninger, Joan C., 1863 Murray, Andrew W., 4642 Oren, M., 531 Merlie, J. P., 5257 Muscat, George E. O., 4120 Orkin, Stuart H., 2804 Merlino, Glenn T., 4174 Muzyczka, Nicholas, 2513 Orr, A., 1443 Metzenberg, Robert L., 1376 Myers, Richard M., 3122 Orr-Weaver, Terry L., 5292 Meusburger, Herwig, 4212 Ortolan, Loris G., 1602 Meyer, H. E., 3458 Nabeshima, Yo-ichi, 2581 Osheim, Yvonne N., 2811 Meyer-Leon, Leslie, 3784 Nadal-Ginard, Bernardo, 679 Oshima, Robert G., 1540 Michaelis, Susan, 1309 Nagao, Ronald T., 11 13 Oshima, Yasuji, 955 Michels, Corinne A., 1027 Nakajima, Noboru, 4028 Oskarsson, Marianne K., 923 Michnoff, Carolyn H., 893 Nakamura, Shun, 3546 Ostman, Arne, 3476 Miki, Toru, 259 Nakamura, Yohko, 3934, 5561 Ostrowski, Michael C., 3872 Milgrom, Edwin, 5323 Nakata, Atsuo, 267 Overell, Robert W., 540, 1803 Miller, A. Dusty, 1725 Nakatsuji, Norio, 3553 Miller, Edward J., 1179 Nakayama, Naoki, 3556, 3777, 5410 Pabich, Edward K., 2964 Miller, 0. L., Jr., 2811 Nam, Hong Gil, 4328 Pachnis, Vassilis, 4707 Miller, Paul F., 5439 Nathenson, Stanley G., 4342 Pachter, Joel S., 1224 Miller, Rebecca, 655 Nau, Marion, 186, 3373 Padmanabha, Ramesh, 4981 Miller, S. C., 2295 Nawotka, Kevin A., 1408 Paigen, Kenneth, 2117 Miller, Samuel I., 2597 Needham-Vandevanter, Donald R., 1525 Palella, Thomas D., 457 Miller, Thomas, 4492 Needleman, Richard B., 1027 Palmer, Jeffrey D., 1474 Minna, John, 186, 3373, 4381 Neff, Norma, 3094 Pancoast, Thomson C., 4889 Minna, John D., 2668 Negishi, Kazuo, 347 Papas, Takis S., 3080, 4700 Mis, Joseph R. A., 978 Neilson, Lorna, 91 Papayannopoulou, Thalia, 4917 Mishina, Yuji, 2604 Nellen, Wolfgang, 153 Pappu, Sita S., 1489 Misulovin, Ziva, 4877 Nelsen, Barbara, 3526 Park, Joo-Hung, 2536 Mitchell, Herschel K., 3550 Nelson, Donald J., 778 Parker, Roy, 3150 Miwa, Takeshi, 4110 Nelson, Stanley F., 441 Parkin, Neil, 2875 Miyajima, Atsushi, 2214 Nelson, W. James, 632 Parsons, Ronald L., 3303 Miyatake, Shoichiro, 5581 Newburger, Peter E., 2804 Parsons, Sarah J., 497 Mobley, W. C., 2456 Newman, Karen M., 2933 Partaledis, Judith A., 3647 Mohler, J. Dawson, 1481 Newman, Thomas C., 2394 Partono, Stephanus, 2562 Moldave, Kivie, 4217 Ng, Sun-Yu, 1790 Pasieka, Karen B., 2267 Moloney, M. Bridget, 2664 Nibert, Max L., 273 Pastan, Ira, 3316 Mondelo, Chiara, 1336 Nicholson, Robert, 2875 Paterson, Bruce M., 1361 Moore, Charleen M., 1525 Nicolas, Alain, 5292 Pathak, Vinay K., 993 Moore, Claire L., 226 Nielsen, B., 1216 Patient, Roger K., 1301 Moore, Kateri A., 5116 Nienhuis, Arthur W., 963 Patil, Nila, 3160 Morabito, Maria A., 1570 Nihigaki, Takashi, 353 Patterson, Mark, 293 Moran, Betty, 1756 Nikawa, Jun-ichi, 2159 Paucha, Eva, 1380 Morello, Laura, 1345 Nikodem, V. M., 3542 Paul, Eileen C. A., 1275 Moren, Anita, 3476 Niman, Henry, 2251 Paule, Marvin R., 747, 1940 Morgan, John G., 2628 Nimer, Stephen D., 1979 Paulson, K. Eric, 4966, 5541 Morgan, William F., 4204 Nir, Uri, 982 Pavlovic, Branka, 5513 Morimoto, Richard I., 393, 4736 Nishikura, Kazuko, 770 Pawar, Shashi, 3058 Morin, Gregg B., 4450 Nishimori, Katsuhiko, 2097 Pawson, T., 2655 Morinaga, Tomonori, 5179 Nishizawa, Masahiko, 347 Pawson, Tony, 578 Morioka, H., 3542 Niwa, Hideo, 267 Payne, Linda S., 2999 Morita, Elaine A., 1979 Nogi, Yasuhisa, 4991 Pays, Annette, 2166, 2367 Morla, Alex O., 2214 Noguchi, Tsuyoshi, 2604 Pays, Etienne, 2166, 2367 Morrison, Alan, 1179 Nolan, J. A., 1821 Pear, Warren S., 441 Morrison, Deborah K., 176 Nomura, Masayasu, 3997 Pearlberg, Joseph, 4225 Morrow, Jon S., I Nori, Mukund, 833 Pearlman, Ronald E., 2572 Morse, Herbert C., III, 301 Notario, Vicente, 259 Pech, Michael, 284 Moscatelli, David, 2933 Pei, Rui, 2860 Moses, Harold L., 3088 Oberhuber, Hermann, 4212 Pelham, Hugh R. B., 5040 Mosher, Deane F., 4234 Obinata, Masuo, 2604, 5545 Pellegrini, Maria, 91 Moss, Bernard, 1709 O'Brien, Deborah A., 828, 3260 Pelletier, Jerry, 1103 Moss, Jennifer Barnett, 2620 3104 Pellicer, Angel, 786, 2233 Moss, Larry G., 2620 O'Brien, Stephen J., Mosser, Dick D., 4736 Oechsner, Ulrich, 5108 Pellman, David, 2675 Mowatt, Michael R., 4055 Oetliker, Michael, 1275 Pennock, David G., 2681 Moyle, Matthew, 321 Ogawara, Hiroshi, 1019 Perera, Julian, 2140 Mucenski, Michael L., 301 Ogden, Jill, 2989 Perlman, Philip S., 2361 Mueller, Peter P., 3827, 5439 Ogrydziak, David M., 4904 Perlmutter, Roger M., 540, 3058 Muhich, Michael L., 3837 Ohshima, Yasumi, 4484 Perry, Michael, 3676 Muldoon, Leslie L., 2247, 2479 Oishi, Michio, 2097, 3311, 5545 Perry, Robert P., 930 Muller, Gunter, 5108 Okarma, Thomas B., 3988 Perry, W. Michael, 2896 Muller, M. T., 3661 Oliff, Allen, 2999 Persson, Hakan, 452 Muller, William J., 5000 Olson, Eric N., 2896 Petersen, Dan D., % Mulligan, Pamela K., 1481 O'Malley, Patrick J., 1123 Petersen, Nancy S., 3550 viii AUTHOR INDEX MOL. CELL. BIOL.

Peterson, Alan C., 5072 Rao, Tekmal R., 1085 Roufa, D. J., 4314 Peterson, Craig L., 4972 Rappaport, Jay, 3136 Roussel, Martine F., 5026 Peterson, M. Gregory, 2664 Rathjen, Peter D., 2989 Roussou, Irene, 2132 Peterson-Torchia, Marilyn, 5528 Ratner, David 1., 2779 Ruben, Martha, 406 Petes, Thomas D., 595, 2942 Rauch, Claudine, 5323 Rubin, Eric J., 418 Petrillo-Peixoto, Maria L., 5188 Raum, Michael G., 3129 Ruddle, Frank H., 5280 Peverali, Antonio F., 1336 RayChaudhury, Amlan, 722 Rudin, Norah, 3918 Philippe, Jacques, 4877 Raymond, Martine, 2770 Rudnicki, Michael A., 406 Philippsen, Peter, 2523 Raymond, Vincent, 2251 Ruiz, Joseph C., 4302 Philipsen, J. N. J., 4557 Reddy, Sita, 704 Ruppert, John M., 3104 Phillips, Robert A., 2082 Redner, Robert L., 963 Rushforth, Alice M., 794 Pierce, Jacalyn H., 5570 Reed, Steven I., 2484, 2976 Rusovick, Kama M., 5448 Pierce, Mary K., 978 Reeder, Ronald H., 4282 Rutter, W. J., 2456 Pikaard, Craig S., 4282 Rekosh, David M., 3008 Rutter, William J., 982, 2620 Pinkham, Jennifer, 655 Renshaw, Mark W., 4547 Ruusala, Aino, 2869 Pious, Donald, 3734 Replogle, Robert E., 1715 Ryffel, Gerhart U., 5323 Pitts, Sharon L., 473, 1748 Resendez, Elpidio, Jr., 4579 Piwnica-Worms, Helen, 1736 Resh, Marilyn D., 1896, 4295 Saez, Lino, 5378 Platt, Terry, 3423 Resnitzky, Dalia, 2828 Safer, Brian, 105 Plotz, Paul, 4433 Rettenmier, Carl W., 1795, 5026 Saga, Yumiko, 4889 Pluthero, Fred G., 169 Revelant, Olivier, 1319 Saito, Izumu, 17 Pohl, Jens, 2078 Reyes, Evangelica, 2082 Saito, Toshiyuki, 1019 Polisky, Barry, 4765 Reynolds, Wanda F., 5056 Sakiyama, Shigeru, 3929, 3934, 5561 Pollenz, Richard S., 794 Rhoads, D. D., 4314 Sakiyama, Takeshi, 203 Pollok, Brian A., 930 Riabowol, Karl T., 1670 Salazar, Edmund P., 1137 Ponta, Helmut, 5323 Richter-Mann, Lizabeth, 2713 Saltzman, Alan, 3136 Ponton, Andrd, 3227 Ricketts, Michael H., 1460 Sampson, Kathleen E., 4685 Popoff, Michel R., 418 Riemen, Mark W., 2999 Samuelson, L. C., 1197 Por, S; B., 3458 Rienhoff, Hugh Young, Jr., 3710 Samuelson, Linda C., 3857 Portella, Giuseppe, 2261 Rifkin, Daniel B., 2933 Sanders, Nancy J., 1421, 3571 Porter, Gregory, 1580, 5575 Rinaldi, A., 1443 Sandmeyer, Suzanne B., 5245 Pot, David A., 1947 Rine, Jasper, 210, 3797 Santangelo, George M., 4217 Potter, M., 2705 Riordan, Maureen F., 5310 Santoro, Massimo, 2261 Potter, Matthew B., 778 Rixon, Mark W., 713 Santos, Eugenio, 3043 Powelson, Mark A., 515 Robbins, Keith C., 259, 284 Sap, J., 1970 Poyton, R. O., 4537 Roberts, Anne N., 2411 Sapolsky, Ronald J., 2184 Pozzatti, Rudy, 2984 Roberts, Thomas M., 176, 1380, 1736 Sariban, Eric, 340, 3951 Prakash, Louise, 1179 Robins, Diane M., 2350 Sartor, Carolyn I., 5310 Prakash, Satya, 3619 Robinson, Jane S., 4936 Sasada, Reiko, 588 Prasad, Paruchuri V., 3303 Robson, Ian B., 3143 Sasaki, Hiroki, 5545 Preer, John R., Jr., 4765 Rockett, Douglas L., 3260 Sastry, Kedarnath N., 605 Prenger, Joe, 3136 Roder, J. C., 2655 Sato, Yasufumi, 2933 Presutti, Carlo, 4792 Roderick, T., 2705 Satoh, Takaya, 3546 Pribyl, Thomas M., 5369 Rodgers, Claire, 3683 Sauer, Monica K., 1011 Price, Peter, 5159 Rodgers, Linda, 2159 Saule, S., 1835 Privalsky, Martin L., 4510 Rodland, Karin D., 2247, 2479 Sausville, Edward, 186, 3373, 4381 Prochownik, Edward V., 884, 3683 Roeder, G. Shirleen, 4009 Sausville, Edward A., 2668 Propst, Friedrich, 923 Roeder, Robert G., 1906, 4028 Sawadaishi, Kazuyuki, 5179 Prowse, Karen R., 42 Roger, P. P., 2494 Sawchenko, Paul, 2251 Prusiner, Stanley B., 5528 Roilides, Emmanuel, 3943 Scarpulla, Richard C., 35 Prywes, R., 2302 Romanelli, Michael F., 2917 Schaffner, Gotthold, 1076 Pulak, Rock A., 3748 Rood, Kirsten L., 5310 Schalch, Heidi, 4716 Purchio, A. F., 2229 Rorsman, Fredrik, 571, 2753 Schaufele, Fred, 1076 Purchio, Anthony F., 4162 Rosamond, John, 293 Scher, Charles D., 36% Rosbash, M., 3755 Schiestl, Robert H., 3619 Qasba, P. K., 2288 Rose, John K., 2869 Schiff, Leslie A., 273 Qiu, Fei-Hua, 4896 Rosen, Jeffrey M., 3183 Schildkraut, C. L., 2149 Quail, Peter H., 4840 Rosen, Ora M., 1638 Schildkraut, Carl L., 4958 Quatannens, B., 1835 Rosenberg, L. E., 1821 Schimke, Robert T., 2822 Queen, Cary, 511 Rosenberg, Leon E., 5150 Schimmel, Paul, 1800, 2690 Quinlan, Margaret P., 3191 Rosenberg, Marorie, 722 Schindler, Daniel, 993 Quinn, Patrick G., 3467 Rosenberg, Naomi, 5216 Rosenberg, Nathan, 5132 Schirrmacher, Volker, 2078 Quitschke, Wolfgang, 1361 Rosenberg, Robert D., 5588 Schlegel, Richard, 4071 Rosenblatt, Margery F., 3864 Schlessinger, J., 1970, 2302 Racaniello, Vincent R., 1103 Rosenthal, Lawrence S., 778 Schlessinger, Joseph, 1831 Radler-Pohl, Adriana, 2078 Ross, Jeffrey, 1697 Schlokat, Uwe, 5549 Railey, Johnny F., II, 1147 Ross, Susan R., 3382 Schmidt, Lucy J., 480 Raines, Maribeth A., 4868 Rothblum, Lawrence I., 3406 Schmidt, Martin, 923 RajBhandary, Uttam L., 361 Rothstein, Rodney, 5132 Schneider, William P., 2211 Rajkovic, Aleksandar, 4745 Rothstein, Thomas L., 1371 Schoneberg, Christa, 3891 Ramakrishnan, Lalita, 5216 Rotter, Varda, 2078 Schreurs, Jolanda, 2214 Rao, C. Durga, 259, 284 Rottman, Fritz M., 4745 Schroll, Christopher T., 457 VOL . 8, 1988 AUTHOR INDEX ix

Schuh, Susan M., 2465 Sittman, Donald B., 4406 Stuart, Kenneth, 1259 Schumacher, Robert I., 2822 Skolnik-David, Hagit, 226 Stuart, S., 2149 Schumperli, Daniel, 1518 Skoultchi, Arthur I., 1887 Stumph, William E., 5566 Schwager, Christian, 4416 Skowronski, Jacek, 1385 Sturani, Emmapaola, 1345 Schwartz, Robert J., 241, 4587 Skup, Daniel, 3227 Sturzbecher, H.-W., 3740 Schweinfest, Clifford W., 3080 Slagel, Valerie K., 4566 Styles, Cora A., 2848 Sclafani, Robert A., 293 Slobin, Lawrence I., 1085 Su, Li-Kuo, 145 Scolnick, Edward M., 52 Small, D., 522 Subramaniam, M., 480 Scott, Gary K., 3670 Smith, Alan E., 1736 Subramanian, Kiranur N., 1509 Scott, James, 571 Smith, Christopher W. J., 679 Suemori, Hirofumi, 3553 Seebeck, Thomas, 2166 Smith, Deborah H., 3882 Sugano, Sumio, 2675 Seedorf, Udo, 605 Smith, Douglas H., 2555 Sugiyama, Hirotaka, 267 Seeger, R., 522 Smith, E., 3458 Suhan, Joseph P., 5059 Segal, Shoshana, 2668 Smith, Larry J., 974 Sumegi, Janos, 441, 3168 Segalat, Laurent, 4459 Smith, M. Mitchell, 945 Sun, Xiao-Hong, 5200 Segall, Jacqueline, 912 Smith, Michael, 884 Surdin-Kerjan, Yolande, 5132 Segatto, Oreste, 5570 Smith, Patricia P., 1863 Sutcliffe, J. Gregor, 4518, 4524 Segawa, Kaoru, 4190 Snapka, Robert M., 515 Suter, Beat, 3322, 3332 Sehgal, Amita, 2242, 3160 Snowden, Margaret M., 5331 Sutton, Richard E., 494 Seifter, Eric, 186 Snyder, Michael, 2184 Suzuki, Yuriko, 4991 Seiki, Motoharu, 466, 5581 Sogo, Jose M., 3026 Swanson, Kitrena T., 1449 Selby, M. J., 2456 Soldati, Dominique, 1518 Swanson, Maurice S., 2237 Sen, Ganes C., 4289 Sollner-Webb, Barbara, 1001 Symington, Lorraine S., 595 Sen, Ranjan, 3526 Solomon, Frank, 2730 Szeles, Anna, 441 Sengupta, D. N., 2288 Solski, Patricia A., 3960 Szostak, Jack W., 4642, 5292 Sentenac, Andre, 3997 Solter, Davor, 5470 Seraphin, B., 3755 Sommer, Doris, 2140 Tafuri, Sherrie R., 794 Seuanez, Hector N., 3104 Sonenberg, Nahum, 1103, 2875 Taga, Tetsuya, 3546 Severinsson, Liv, 3476 Sonenshein, Gail E., 1371 Tai, Joseph Y., 2999 Shabb, John B., 3467 Sopta, Mary, 1602 Takahashi, Masahide, 1853 Shalloway, David, 704, 4541 Spain, Brian H., 5016 Takahashi, Mitsuko, 347 Shani, Moshe, 1006 Spanopoulou, Eugenia, 3847 Takaku, Fumimaro, 3770 Shapiro, Robert A., 1957 Spiazzi, Annalisa, 674 Takebe, Yutaka, 466 Sharp, Phillip A., 226, 361, 988, 1290 Spiegelberg, T., 3338 Takeda, Kyoko, 3929 Sharp, Stephen J., 1266, 4441 Spiegelman, Bruce M., 1380 Takenaga, Keizo, 3929, 3934, 5561 Sharp, Z. Dave, 5432 Spizz, Gwendolyn, 28% Takeya, Tatsuo, 1826 Shaul, Yosef, 2449 Sporn, Michael B., 1247 Talarico, Daniela, 1336 Shaw, Jeng-Pyng, 1715 Sprague, George F., Jr., 309, 551 Talmage, David A., 2309 Shea, Cathy, 854 Sprague, Karen U., 624, 5504 Tamame, Mercedes, 3043 Sheffery, Michael, 3215, 4270 Spritz, Richard A., 4787 Tamaoki, Norikazu, 1816, 2651 Shen, Fung-Win, 4889 Squire, Jeremy, 2082 Tamaoki, Taiki, 5179 Shen, Rong-Fong, 4362 Sreevalsan, T., 2288 Tan, T.-H., 531 Sheng, Morgan, 2787 St. Louis, James, 1380 Tanaka, Kazuma, 3556 Shenk, Thomas, 4477 Staeheli, Peter, 3065, 4518, 4524 Tanaka, Kenichi, 1857 Sherman, Fred, 1591, 4533 Stallcup, Michael R., 833 Tanhauser, Susan M., 996 Shero, James H., 2523 Stamatoyannopoulos, George, 4917 Taniguchi, Shigehiko, 1816 Sherr, Charles J., 1795 Stanway, Clive A., 2989 Tatchell, Kelly, 505 Sherry, Barbara, 2394 Stark, George R., 17 Taylor, Annette K., 4197 Sherwood, Peter W., 615 Stavenhagen, Jeffrey, 2350 Taylor, Benjamin A., 301, 5528 Sherwood, Steven W., 2822 Stefano, James E., 2052 Taylor, Milton W., 2536 Shibuya, Masabumi, 1816 Stehelin, D., 1835 Taylor, Susan Y., 5417 Shih, Cheng-Kon, 3094 Stein, Jill C., 1160 Taylor, Wayne E., 4552 Shimamura, Akiko, 4257 Stein, Robert, 1206 Tayoshima, Kumao, 2651 Shirakata, Masaki, 2581 Steinberg, Jacob J., 786 Tebabi, Patricia, 2166 Shows, Thomas, 1775 Steinert, Maurice, 2166, 2367 Telerman, Adam, 1498 Shows, Thomas B., 722 Stern, David F., 3969 Temin, Howard M., 2328 Shulman, Marc J., 4041 Stemnberg, Edward A., 2896 Tennyson, G. E., 3542 Shuster, Elizabeth O., 3150 Stevens, Audrey, 2005 Tewari, K. K., 1216 Siddiqui, Ayesha H., 4634 Stevens, Craig W., 2089 Thatcher, Thomas, 2681 Siebenlist, Ulrich, 867 Stewart, M. J., 4314 Thayer, Mathew, 1236 Sigal, Irving S., 52 Stewart, Sheri A., 1137 Theodorakis, Nicholas G., 4736 Siliciano, Paul G., 3150 Stewart, Timothy A., 473, 1748 Thevelein, Johan M., 3051 Silverman, Larry J., 457 Stillman, Bruce W., 1923 Simmons, Trey, 3150 Stimac, Eva, 3734 Thiele, Carol J., 1677 Simon, Daniela, 25 Stoeckle, Mark Y., 2675 Thiele, Dennis J., 2745 Simon, Jeffrey A., 4727 Stone, James C., 3565 Thireos, George, 2132 Simons, J. Paul, 4821 Storms, Reginald K., 4616 Thomas, Dominique, 5132 Singer, Dinah S., 695 Storti, Robert V., 3591 Thompson, Craig, 3373 Singer, Maxine F., 1385 Strayer, John M., 515 Thompson, Craig B., 3809, 3820 Singer, S. J., 564 Stroeher, Virginia L., 4143 Thompson, John A., 105 Singleton, C. K., 10 Strominger, Jack L., 3809 Thompson, Larry H., 1137 Sipes, Nancy J., 3088 Stroud, Robert M., 3797 Thompson, Mary Ann, 2984 Sittisombut, Nopporn, 2034 Struhl, Kevin, 664 Thornell, Anders, 1625 x AUTHOR INDEX MOL. CELL. BIOL.

Thorsness, Mary, 3797 Voellmy, Richard, 3761 Wiebauer, Karin, 2042 Tilghman, Shirley M., 1169, 4707 Vogelstein, B., 522 Wieczorek, David F., 679 Ting, Jerry, 4250 Vogelstein, Bert, 3104 Wiener, Francis, 441 Tinker, Donald A., 540 Vollrath, Douglas, 1469 Wiestler, Otmar D., 502 Tippetts, M. Todd, 4570 Von Hoff, Daniel D., 1525 Wigler, Michael, 2159 Tiwari, Raj K., 4289 Vosatka, Robert J., 1670 Wilcox, Josiah N., 3415 Tobler, Andreas, 3432 Voss, Hartmut, 4416 Williams, Bryan R. G., 3227 Toh-e, Akio, 3556 Vrana, Kent E., 1684 Williams, David A., 3864 Tokunaga, Katsuo, 3929, 5561 Vu, Loan, 3997 Williams, J. G., 3458 Tollervey, David, 3282 Vuocolo, Gerald A., 2999 Williams, Jim A., 1489 Torchia, Timothy E., 3439 Williams, John S., 2763 Tornow, Joanne, 4217 Wachsman, William, 1979 Williams, K. L., 3458 Torri, Al F., 4625 Wadsworth, Samuel C., 778 Williams, Lewis T., 5126 Torti, F. M., 2295 Wager-Smith, Karen, 5116 Williams, Mark A., 1186 Toschi, Luisella, 1345 Wagner, Richard W., 770 Williams, Norma P., 3827 Tower, John, 1001 Wagner, Ronald, 3094 Williams, Trevor, 3898 Toyoshima, Kumao, 1019 Wahl, Alan F., 5016 Willumsen, Berthe M., 3565 Traut, Wolfgang, 903 Wahl, Geoffrey M., 1525, 4302 Wilson, Ellen T., 624 Travali, Salvatore, 1551 Wahlstr0m, Gunilla, 441 Wilson, Ian A., 2159 Treger, Janet M., 1132, 2428 Waldman, Alan S., 5350 Wilson, Robert B., 505 Treisman, Jessica E., 1570 Wall, Doris A., 2242 Wilson, Wilma, 2989 Tremethick, David, 4257 Wall, Randolph, 4197 Wilusz, Jeffrey, 4477 Trempe, James P., 1657 Walls, Jenna D., 3448 Winegar, Richard A., 4204 Troen, Bruce R., 3316 Walsh, Charles J., 2280 Wing, Rod A., 4904 Tronick, Steven R., 259 Walsh, Kenneth, 1800 Winkler, M., 1970 Troutman, W. Brad, 5268 Walter, Gernot, 502 Winston, Fred, 822, 4608 Trueblood, C. E., 4537 Wan, Yu-Jui Yvonne, 203 Wirth, Dyann F., 2597 Tsai, Ming-Jer, 2070 Wang, Jean Y. J., 2214, 4547 Wise, Jo Ann, 1580, 5575 Tsai, Sophia Y., 2070, 4362 Wang, Lee-Ho, 2070 Witte, Michael M., 3726 Tso, J. Yun, 5200 Wang, Shirley S., 5140 Witte, Owen N., 4079 Tsukuda, Toyoko, 3703 Wang, Teresa S.-F., 5016 Wittekind, Michael, 3997 Tullius, Thomas D., 1684 Wang, Yenyun, 196 Wold, William S. M., 3291 Tung, Jwu-Sheng, 4889 Warren, Stephen L., 632 Wolfner, Mariana F., 4756 Tung, Kenneth S. K., 996 Warrior, Rahul, 4598 Wolgemuth, Debra J., 2925 Tyrrell, Rex M., 5425 Watanabe, Hajime, 1290 Wong, Albert J., 3104 Watanabe, Motoo, 1857 Wong, Annie, 3397 Ueda, Kazumitsu, 3316 Watanabe, Shinichi, 1247 Wong, Jerry K.-C., 321 Uemura, Hiroshi, 938 Watanabe, Toshio, 3311 Wong, Scott W., 5016 Ueno, Kenju, 4529 Waterston, Robert H., 3627 Wong, Tai Wai, 3467 Ueyama, Yoshito, 1816, 2651 Watowich, Stephanie S., 393 Wong, Timothy, 5232 Ullrich, A., 1970, 2302 Watson, Gordon, 2117 Woo, Savio L. C., 4362 Ullrich, Axel, 1831 Watson, Roger J., 3938 Wooden, Scott K., 4579 Umlauf, Scott W., 3784 Way, James, 3373 Woodworth, Craig D., 4492 Underwood, Douglas C., 5504 Weber, Christine A., 1137 Wooley, John, 2884 Weber, Michael J., 138 Worcel, Abraham, 4257 van de Putte, Pieter, 2195, 2204 Wegrzyn, Ronald J., 2999 Worden, Jenny, 2335 Van der Ploeg, Lex H. T., 854 Wei, Randy, 655 Wrange, Orjan, 1398 Vande Woude, George F., 923 Weil, Thomas, 2896 Wright, R. M., 4537 van Muijen, Goos N. P., 2204 Weil, Thomas S., 3676 Wrighton, N., 130 Van Ness, Brian G., 2610 Weinberger, Judah, 988 Wu, Guang-Jer, 1147 Vannice, James L., 5549 Weinmann, Roberto, 3136 Wu, Ray, 5200 van Pelt-Heerschap, Hilde, 2204 Weinrich, S. L., 2456 van Santen, Vicky L., 4787 Weisser, Karen E., 1803 Xanthopoulos, Kleanthis G., 1055 Van Slyke, B., 4314 Weissman, Bernard, 557 Xanthoudakis, Steven, 3397 Van Wyke Coelingh, Kathleen, 3129 Weissman, Bernard E., 3088 Xiong, Yue, 114 Varma, Madhu, 4659 Weissman, Irving L., 2647 Xu, Faming, 4185 Varmus, Harold E., 2435 Weissmann, Charles, 3065 Varnum, Brian C., 4570 Welch, William J., 5059 Yaciuk, Peter, 704 Vashishtha, Anshu, 2675 Wells, Alan, 4561 Yakushinji, Miki, 4190 Vass, William C., 3565 Wells, Julian R. E., 4576 Yamada, Masa-atsu, 347 Veillette, Andre, 4353 Westaway, David, 5528 Yamamoto, Tadashi, 1019, 2651 Veit, Bruce E., 4949 Westermark, Bengt, 2753 Yamazaki, Hitoshi, 1816 Velcich, Anna, 2177 Westin, Eric, 884 Yang, Jia-Ling, 3364 Vennstrom, B., 1970 White, Charles I., 2342 Yang, Yih-Sheng, 4406 Vennstrom, Bjrn, 4416 White, Elizabeth M., 4780 Yang-Feng, Teresa L., I Verma, Inder M., 2251 White, James H., 1253 Yang-Yen, Hsin-Fang, 3406 Vesco, Cesare, 5495 White, Martyn K., 138 Yanicostas, Constantin, 4459 Vijaya, S., 1709 White, Morris F., 176 Yanofsky, Charles, 1469, 2211, 2411 Villalon, Deborah, 5116 White, Robert G., 2722 Yao, Meng-Chao, 1664, 3947 Villarreal, Luis P., 1993 Whyte, Peter, 3191 Yeh, Dong-Bor, 5280 Vincent, Alain, 4459 Wickner, Reed B., 938 Yelick, Pamela C., 996 Vizard, Douglas, 2896 Wiebauer, K., 1197 Yen, Tim J., 1224 VOL. 8, 1988 AUTHOR INDEX xi

Yew, Nelson S., 4416 Zafarullah, Muhammad, 4469 Zhan, Xi, 3487 Yip, Carli, 5386 Zagorski, John, 3282 Zhang, Jun-wu, 4917 Yoffe, Olla, 1006 Zakeri, Zahra F., 2925 Zhao, Qian, 427 Yokota, Kyoko, 466 Zakian, Virginia A., 2257 Zhu, X. X., 5047 Yoon, Kyung Pyo, 1509 Zakut-Houri, Rina, 1498 Zhu, Zheng, 1947 Yoo-Warren, Heeja, 4707 Zaller, Dennis M., 1932 Ziegler, Steven F., 540 Yoshida, Michihiro C., 3770 Zapp, Maria L., 814 Ziff, Edward, 2177 Yoshida, Mitsuaki, 466, 5581 Zasloff, Michael, 4433 Ziff, Edward B., 1670, 3882 Young, Elton T., 1868, 1915, 4552 Zavala, Fidel, 1709 Zillmann, Martin, 814 Young, Judy C., 4079 Zechner, Rudolf, 2394 Zippel, Renata, 1345 Young, Michael W., 5378 Zehnbauer, B. A., 522 Young, Patricia, 3550 Zelent, Arthur, 5159 Zitomer, Richard S., 2275, 4651 Youngren, Susan D., 1421 Zenke, Martin, 4416 Zullo, John N., 5080 Yu, Hua, 1932 Zerler, Brad, 1756 SUBJECT INDEX VOLUME 8

2,um plasmid 5' sequences capable of conferring EIA transactivation, 353 copy number and partition, 4949 serum- and cycloheximide-depen- protein-binding sites on products of ear- S. cerevisiae, 4949 dent regulation, 480 ly-region IA, 3955 transcription regulators, 4949 mouse, 480 Adenovirus type 12 3T3-LI cells human, 267 human, 1863 c-myc y-Actin U2 small nuclear RNA, 1863 cell differentiation, 1614 gene structure and expression, 1775 Adenylate cyclase 5S RNA genes human, 1775 RAS proteins, 52 D. melanogaster, 1266 Actin gene S. cerevisiae, 52 transcription, 1266 T. brucei, 2166 Adenylate cyclase gene X. laevis, 4257 a-Actin gene S. cerevisiae, 5555 X. laevis S150 extract chicken, 4587 Adenylate deaminase genes transcriptional efficiency, 5056 promoter, 4587 amplification of rearranged sequences, 7SL trans-Acting factors 17 S. pombe RNA, 1580 murine erythroleukemia cells, 130 Adenylyl cyclase 12S or 13S adenoviral EIA gene product ADE8 S. cerevisiae, 2159 rat epithelial cell immortalization, 1036 S. cerevisiae, 1253 ADP-ribosylation 25S ribonucleoprotein complex Adeno-associated virus 21-kDa G protein, 418 assembly in vitro, 2052 DNA excised from recombinant plas- C. botulinum, 418 72-Base-pair repeat mids, 2513 ADRI SV40, 1509 vector system, 3988 S. cerevisiae, 1868 78-Kilodalton glucose-regulated protein Adenosine deaminase ADR1 protein CEF, 2675 human, 5116 binding to upstream activating sequence p6Ov-src induction, 2675 mouse, 5116 of ADH2, 4552 S-Adenosyl transferase S. cerevisiae, 4552 A431 cells S. cerevisiae, 5132 ADR1 transcriptional activator epidermal growth factor receptor, 1345 SAM2, 5132 S. cerevisiae, 2125 A2318 Adenovirus a-Factor pheromone GRP78 transcription, 4579 EIA S. cerevisiae, 1309 Abelson tyrosine kinase growth-regulating domains, 1756 African green monkey kidney D. melanogaster, 843 HeLa cells, 1765 epidermal growth factor receptor pro- c-abl mRNAs ras cooperation activity, 2177 moter SI nuclease sensitivity, 4174 mouse, 4547 rat, 1756 African green monkey kidney cells v-abl TATA box transcription factor activa- UVB radiation, 5425 lymphoid specificity, 234 tion, 1765 AKXD murine myeloid tumor tyrosine kinase region, 234 ElA-like activity Evi-J viral integration site, 301 Acanthamoeba castellanji mouse, 3553 Albumin genes RNA polymerase I, 747 E2 hepatoma-specific nuclear factor, 5179 rRNA promoter poly(A) site downstream elements af- human, 5179 single base substitutions, 747 fect cleavage activity, 1839 Alkaline extracellular protease rRNA transcription, 1940 E3 mRNA, 3291 4 Y. lipolytica, 4904 transcription, 747 early-region gene transcription initiation factor, 747 transcription factors, 1290 a,-Acid glycoprotein ACE] Ella hepatocyte-stimulating factor, 42 metallothionein gene regulation, 2745 late promoter, 1906 02 interferon, 42 S. cerevisiae, 2745 transcription, 1906 interleukin-1, 42 Acetylcholine receptor 5- and -y-subunit HeLa cells, 1765 rat, 42 genes major late promoter transcription factor Alpha-l-antitrypsin gene transcription mouse, 5257 CAAT-binding factor. 2628 hepatic trans-acting factors, 4362 Acetylcholine receptor-related gene -y-fibrinogen promoter, 2628 human, 4362 D. melanogaster, 778 Spl, 2628 al(I) collagen gene expression ACP2 mouse, 3553 human, 4851 HMGI-like protein, 1282 serotype 5 Ela protein transcriptional control, 4851 S. cerevisiae, 1282 BRK cells, 3882 a Heavy-chain glycosylation Actin transcriptional regulatory regions, 3717 immunoglobulin A degradation, 4197 cytoskeletal Adenovirus type 2 mouse, 4197 cDNA clones, 3929 Ela Alpha tubulin mouse, 3929 metastatic potential, 2984 divergent form, 996 mRNA expression, 3929 rat, 2984 996 L3 polyadenylation site, 226 mouse, human, 1790 polyadenylation-specific complexes, 226 a-Factor microfilament protein composition, 1790 upstream factors S. cerevisiae, 1915 mouse, 3929 DNA affinity labeling, 105 signal sequence mutations, 1915 a-Actin VARNAI gene, 1147 a-Specific gene control cardiac, 4110 Adenovirus type 5 S. cerevisiae, 309 human, 4110, 4120 EIA 12S protein Alphoid DNA protein factor interaction, 4110 primary rat epithelial cell immortaliza- CHO cells, 3611 trans-acting factor, 4120 tion, 3191 chromosome instability, 3611 ,-Actin EIA transactivation human, 3611 enhancer, 267 EIV promoter susceptibility, 353 Altered cytoplasmic domains gene EIV promoter susceptibility transferability, 2869 xii VOL . 8, 1988 SUBJECT INDEX xiii

vesicular stomatitis virus glycoproteins, phv transcription, 4840 CAAT-binding factor 2869 phytochrome, 4840 adenovirus major late promoter tran- Alu Avian erythroblastosis virus scription factor, 2628 common parental Alu sequence, 4566 v-erbA protein y-fibrinogen promoter, 2628 amdR genetic dissection, 4510 Spl, 2628 A. nidulans, 3532 Avian leukosis virus cab amdS regulation B-cell lymphomas A. sativa, 4840 A. nidulans, 2589 c-mvc genes, 2659 phytochrome, 4840 N4-Aminocytidine Cachectin/tumor necrosis factor mouse B 1-Alu expression lipoprotein lipase gene, 2394 mutation induction, 347 pathway, 4433 Caenorhabditis elegans 2-Aminopurine X. Iaei'is, 4433 deletions, 3748 gene induction, 4289 B cells myosin light-chain genes, 5339 human, 4289 chicken, 5358 repetitive DNA with ARS and segrega- Aminotriazole resistance rapid isolation, 5358 tion function in S. cerevisiae, 875 ATRI, 664 v-rel, 5358 Tcl, 737 S. cerevisiae, 664 B lymphocytes tRNAUAG amber suppressors, 3627 Amplicons anti-immunoglobulin antibody, 1371 Calcium dihydrofolate reductase, 5268 cytochalasin, 1371 epidermal growth factor, 557 Amylase genes mouse, 1371 keratinocytes, 557 evolution, 1197 stimulation to enter DNA synthesis mouse, 557 human, 1197 2FI gene, 1371 Calcium-binding protein gene Amylase mRNA y-actin gene, 1371 human, 2402 glucocorticoid, 3857 c-myc gene, 1371 myeloid differentiation, 2402 mouse, 3857 B lymphoid cells Camptothecin Amyloid A gene expression DNA-binding factors, 1812 DNA breakage, 3026 mouse, 3710 Baby hamster kidney cells monkey, 3026 Anarhichas lupus glucogon expression, 4877 SV40, 3026 antifreeze protein genes, 3670 BALB/3T3 cells Candida albicans Androgen-inducible sequences triple-promoter retroviral vectors, 1803 chromosomal map, 4721 mouse, 2117 Basic fibroblast growth factor Carbon regulation mRNA synthesis, 2117 human, 588 S. cerei4siae, 3439 Antifreeze protein genes mouse, 588 Carboxyl-terminal domain wolffish (A. lupus), 3670 B-cell precursors RNA polymerase 11 Antigen receptor response elements DJH recombination arrest, 5216 D. melanogaster, 321 human, 1715 B-cell specificity mammals, 321 interleukin-2 enhancer, 1715 immunoglobulin heavy-chain enhancer, mouse, 330 Anti-immunoglobulin antibody 988 S. cerevisiae, 321 B lymphocyte stimulation, 1371 B-cell stimulatory factor 2 Carcinogens mouse, 1371 interleukin 6, 3546 Chinese hamster embryo cells, 1366 Anti-myc oligomer PC 12 cells mouse L cells, 196 HL60 differentiation, 963 neuronal differentiation, 3546 recombination, 196 Anti-peptide antibody BCRIABL trans activation, 1366 platelet-derived growth factor receptor, lymphoid and myeloid culture transfor- Cardiac actin gene 3696 mation, 4079 human, 406 al-Antitrypsin gene Bent DNA mouse embryonal carcinoma cells, 406 enhancer, 1066 S. cerevisiae, 2763 Cardiac ox-actin promoter mouse, 1055 Beta nerve growth factor human, 4110 Apolipoprotein Al gene chicken, 452 protein factor interaction, 4110 cis-acting regulatory elements, 605 COS cells, 452 "Cassette'" mutagenesis human, 605 rat, 452 p2I-ras effector domain mutants, 3565 Apolipoprotein B gene BmX Cat chromatin structure, 71 transcriptional properties, 624 c-kit, 4896 human, 71 Bombyx mori CDC7 aprt BmX meiosis, 293 CHO cells, 2536 transcriptional properties, 624 mitosis, 293 Arabidopsis thaliana RIBm, 114 S. cerevisiae, 293 chalcone synthase gene, 1985 tRNAAla gene clustering, 5504 CDC25 ARS Bovine papillomavirus RAS mutation, 2980 S. cerevisiae, 2184 4071 S. cerevisiae, 2980 transcription, 2184 E5 transforming protein, Aspergillus nidulans Branched-chain amino acid biosynthesis Cdc28 protein kinase amdR, 3532 LEU3, 2690 phosphorylation, 2976 amdS regulation, 2589 S. cerei'isiae, 2690 S. cerevisiae, 2976 fluFI, 3043 CDC33 ATRI C proteins mRNA cap-binding protein eIF-4E, 3556 aminotriazole resistance, 664 heterogeneous nuclear ribonucleoprotein S. cerevisiae, 3556 S. cerevisiae, 664 complexes, 4477 cDNA Autonomously replicating sequences polyadenylation substrates, 4477 Epstein-Barr virus vector, 2837 S. cerevisiae, 210 Ca2'-mobilizing system fibroblast tropomyosin isoform 2, 5561 U. maydis, 3703 desensitization to serum growth factors, human cells, 2837 Avena sativa 4212 mouse, 5561 cab transcription, 4840 mouse, 4212 rat intestinal mucosa, 4243 xiv SUBJECT INDEX MOL. CELL. BIOL. cDNA gene formation vitellogenin gene Class III transcription factors retroviral vector system, 2328 estrogen response elements, 1123 human, 3017 Cell cycle nuclear factor binding, 4557 promoter binding, 3017 T. thermophila, 2681 Chinese hamster cells Clostridium botulinum Cell-type-specific genes dihydrofolate reductase amplicons, 5268 exoenzyme C3 S. cerevisiae, 551 metallothionein I and 1I induction, 4716 ADP-ribosylation, 418 Cellular protein inactivation nuclear DNA synthesis, 1923 cob S. cerevisiae, 2638 Chinese hamster embryo cells intron 5, 2562 Centromere DNA carcinogen-induced trans activation, S. cerevisiae, 2562 S. cerevisiae chromosome VI, 2523 1366 Cold shock Centromeric DNA Chinese hamster fibroblasts D. discoideum, 153 S. pombe, 754 adenylate deaminase genes Cold stress c-erbB amplification of rearranged sequences, D. melanogaster, 3550 proviral insertional activation, 4868 17 Colony-stimulating factor I quail, 4868 Chinese hamster ovary cells precursor processing by human cDNAs, Chalcone synthase gene 25-kDa phosphoprotein, 4685 5026 A. thaliana, 1985 aprt expression, 2536 receptor Chicken cycloheximide, 2822 tyrosine kinase activity, 1795 78-kilodalton glucose-regulated protein, dhfr amplicons, 2316 con-10 2675 dihydrofolate reductase domain, 5398 N. crassa, 2411 actin microfilaments, 564 double minute chromosomes, 1525 Core histone gene tandem repeat B-cell line isolation EcoRI expression and cytogenetic ef- U. caupo, 4425 rapid method, 5358 fects, 4204 COS-I cells beta nerve growth factor, 452 episomes, 1525 rat somatic cytochrome c gene, 35 DNase I hypersensitivity, 3661 ERCC2, 1137 COS-7 cells epidermal growth factor, 1970 gene amplification, 1525 nuclear sequence-specific DNA-binding c-erbA GRP78 levels protein capture, 982 proteins, 4155 protein secretion, 4063 COS cells erythrocyte anion transport gene histone genes, 1887 beta nerve growth factor, 452 mRNA, 4416 human alphoid DNA, 3611 COUP transcription factor erythroid anion transporter, 1327 interleukin-2 receptors, 3357 rat insulin II gene, 2070 estrogen response elements, 1123 matrix attachment regions, 5398 Cow estrogen responses, 5323 methotrexate resistance, 2822 thrombomodulin gene, 5588 P-globin gene v-mos transfection, 4685 tumor necrosis factor, 5588 transcription termination, 5369 ornithine decarboxylase, 764 COX5a and COX5b glucose deprivation, 2675 pre-pro-transforming growth factor beta, HAP2, 4537 glucose transport, 138 4162 heme, 4537 Hi histone gene-specific factor type I transforming growth factor p pre- REOI, 4537 binding, 4576 cursor, 2229 S. cerevisiae, 4537 histone H5 genes, 1657 UV5 CSF-I integrin P-chain, 564 ERCC2, 1137 human monocytes, 3951 lens cell differentiation, 1414 Chloramphenicol CYCI lens junction formation, 1414 mouse erythroleukemia cells, 3311 S. cerevisiae, 647 membrane protein antigen, 564 Chorion genes upstream activation sequence 2, 647 c-mil RNA, 1835 amplification, 2811 Cyclic AMP mos proto-oncogene homolog, 923 D. melanogaster, 2811 chorionic gonadotropin p subunit gene mouse cells, 1970 Chorion protein gene family cluster, 5100 myosin light-chain {IW3f gene S. mansoni, 3008 human, 5100 I kb of sequence 5' to the start sites, Chorionic gonadotropin p subunit gene neurotransmitter gene transcriptional 1361 cluster regulation, 4225 nerve growth factor, 452 cyclic AMP, 5100 Cyclic AMP phosphodiesterase p60Vsrc, 2675 human, 5100 S. cerevisiae SRA5, 505 pp6Oc-src Chromatin Cyclic AMP signal Ser-17 substitution, 1826 human apolipoprotein B gene, 71 S. cerevisiae ras mutants, 3051 pp6v-src, 1414 S. cerevisiae TDH3, 5513 Cycloheximide progesterone responses, 5323 Chromosomal DNA 5' sequences, 480 protein substrates for tyrosine protein N. crassa, 1469 p-actin gene, 480 kinases, 3035 Chromosome 17 CHO cells, 2822 skeletal actin promoter, 1800 human, 722 D. discoideum, 10 skeletal a-actin gene promoter region, keratin genes, 722 methotrexate resistance, 2822 4587 mouse, 480 skeletal myosin alkali light-chain gene Cilia regeneration myeloid colony-stimulating factor upstream regulatory region, 2581 T. thermophila, 2681 expression, 3432 a-smooth muscle actin gene core pro- cis effects of c-myc mRNA 5' region cys-14+ moter, 241 mouse, 2875 N. crassa, 1504 src, 138 wheat-germ extracts, 2875 Cytochalasin topoisomerase II, 3661 Xenopus, 2875 B lymphocyte stimulation, 1371 transforming growth factor alpha, 1970 CKA1 mouse, 1371 tyrosine protein kinases, 3035 S. cerevisiae, 4981 Cytochrome c vitellogenin II gene Class I major histocompatibility complex COS-1 cells, 35 estrogen receptor-binding sites, 5323 gene gene activation sites, 2275 progesteron receptor-binding sites, pig, 695 rat, 35 5323 regulatory elements, 695 S. cerev'isiae, 2275 VOL . 8, 1988 SUBJECT INDEX xv

T. brucei, 4625 human metallothionein genes, 5331 ribosomal protein S14, 4314 Cytomegalovirus replication ribosome synthesis, 91 enhancer activity, 1809 ,-globin gene activation, 1301 RNA polymerase II Cytoplasmic exchange herpes simplex virus, 3272 carboxyl-terminal domain, 321 T. thermophila, 2681 rabbit skin cells, 3272 RNA splicing, 4143 Cytoskeletal actin SV40, 1509 srv h-i, 4459 cDNA clones, 3929 Vero monkey cells, 3272 TATA box-dependent protein-DNA in- human, 1790 X. laev'is, 1301 teractions microfilament protein composition, 1790 replication origin heat shock promoter, 3204 mouse, 3929 herpes simplex virus, 4018 histone gene promoter, 3204 mRNA expression, 3929 replicon tRNAAsn gene mapping, 1408 transcription, 4441 D19 ribosomal tRNATYr D. discoideum, 3458 mouse, 3891 anticodon, 3332 DAF1 TTFI, 3891 genes, 3322 S. cerevisiae, 4675 synthesis tropomyosin II gene, 3591 DBA fidelity, 3267 ubiquitin genes, 4727 S. pombe, 754 c-fos, 1670 white protein, 5206 Dictyostelium discoideum monkey cell-derived in vitro replica- YPI gene expression, 4756 cell surface glycoprotein PsA, 3458 tion system, 3267 zeste gene product cold shock, 153 rat, 1670 DNA binding, 615 cycloheximide, 10 SV40 vector, 3267 double-strand break repair, 2779 T. thermophila, 3947 EIA expression heat shock, 153 DNA binding human, 4799 homologous recombination, 2779 reticuloendotheliosis virus Ela gene membrane protein gene, 153 long terminal repeat, 5232 adenovirus type 2, 2984 mRNA, 1957 DNA polymerase a metastatic potential, 2984 mRNA decay rates, 4088 human, 5016 rat, 2984 myosin light chain, 794 DNA-binding factors E5 transforming protein prespore-specific gene D19, 3458 B lymphoid cells, 1812 bovine papillomavirus, 4071 protein synthesis inhibition, 10 mouse, 1812 EcoRI Dihydrofolate reductase proteolytic cleavage, 1812 CHO cells, 4204 amplicons, 5268 S. cerevisiae, 210 Eggshell (chorion) protein gene family CHO cells, 2316 DNA-binding proteins S. mansoni, 3008 Chinese hamster ovary cells, 5398 COS-7 cells, 982 Elastase I enhancer matrix attachment regions, 5398 cytomegalovirus enhancer activity, 1809 rat, 893 sn- 1,2-Dioctanoylglycerol hepatitis B virus enhancer and core pro- Elongation factor Tu mouse, 2247 moter domains, 5159 Friend erythroleukemia cells, 1085 VL30, 2247 nuclear sequence specific mRNA stability, 1085 DJH recombination arrest capture by use of SV40-derived mini- Embryonal carcinoma stem cells B-cell precursors, 5216 chromosomes, 982 cloning of active mouse chromosomal DNA polymerase II transcriptional machinery, loci, 3251 adduct removal 1809 Enhancer core sequences human neuroblastoma cell differentia- DNase I polyomavirus, 1993 tion, 3964 chicken, 3661 Enhancers affinity labeling of Ad2 upstream factors, hypersensitivity mouse retrovirus SL3-3, 1625 105 topoisomerase II, 3661 -y-Enteric actin cDNA amplification Dog rat, 5224 L. tarentolae, 5188 pp6 c-src, 632 Enzyme inactivation bent Double minute chromosomes S. cerevisiae, 2647 S. cerevisiae, 2763 CHO cells, 1525 eph binding Drosophila melanogaster receptor tyrosine kinase gene, 3770 D. melanogaster zeste gene product, 5S RNA gene transcription, 1266 Epidermal growth factor 615 Abelson tyrosine kinase, 843 A43, cells, 1345 SV40 T antigen, 1648 acetylcholine receptor-related gene, 778 chicken, 1970 breakage active transport proteins, 5206 c-erbB-2 gene product, 1019 camptothecin, 3026 Antennapedia gene, 4143 glioblastomas, 1816 monkey, 3026 brown protein, 5206 human, 25, 1816, 4561 SV40, 3026 chorion gene amplification, 2811 human adenocarcinoma cells, 1019 Chinese hamster 1923 cold stress, 3550 cells, eve proteins mitogenic blocks, 2302 cleavage DNA binding, 4598 mouse, 1970, 2247 adeno-associated virus, 2513 heat shock, 91 mouse fibroblasts that overexpress D. melanogaster zeste gene product, 615 heat shock protection, 3550 pp60c-src, 497 deletion junctions heat shock regulatory elements, 3761 mouse keratinocytes, 557 T. thermophila, 3947 3-hydroxy-3-methylglutaryl coenzyme A rat, 2479 heteroduplex reductase, 2713 receptor repair, 5292 insulin receptor transcripts, 1638 amplified gene, 4561 S. cerevisiae, 5292 otu, 1481 receptor in human hepatocellular carci- nuclear DNA synthesis in vitro, 1923 p75, 1877 noma-derived cell lines, 25 polyomavirus enhancer elements and P-element-induced vg mutants, 1489 receptor-binding domain, 1831 subelements, 5000 per clock protein, 5378 thyroid cell proliferation, 2494 repair polytene chromosomes, 1877 protein phosphorylation, 2494 xvi SUBJECT INDEX MOL. CELL. BIOL.

transforming growth factor alpha, 1970 DNA binding, 4598 c-fos protein transin gene expression, 2479 Evi-I DNA synthesis, 1670 tumor promoter phorbol ester, 2302 AKXD murine myeloid tumor, 301 rat, 1670 tyrosine phosphorylation of receptor, viral integration site, 301 Fos-related antigen 1345 Exoenzyme C3 fra-1, 2063 VL30 element, 2247 ADP-ribosylation of a 21-kDa protein, rat, 2063 Epidermal growth factor receptor 418 fra-l human, 5477 C. botulinum, 418 Fos-related antigen, 2063 prostatic phosphotyrosyl phosphatase, rat, 2063 5477 a-Fetoprotein Friend erythroleukemia cells Epidermal growth factor receptor promoter gene enhancers, 1169 elongation factor Tu S1 nuclease sensitivity mouse, 1169 mRNA stability, 1085 African green monkey kidney, 4174 a,-Fetoprotein gene Friend murine erythroleukemia cells human, 4174 activation, 1398 c-myb cDNA expression, 884 Episomes glucocorticoid repression, 1398 CHO cells, 1525 rat, 1398 GO/G transition genes Epstein-Barr virus a-Fetoprotein genes c-myc, 3080 cDNA expression in human cells, 2837 hepatoma-specific nuclear factor, 5179 G protein ERA-1 human, 5179 S. cerevisiae pheromone response, 2484 homeobox domain, 3906 FGF-5 oncogene GAL3 mouse, 3906 human, 3487 S. cerevisiae, 3439 retinoic acid, 3906 protein related to fibroblast growth fac- GALII protein c-erbA tors, 3487 S. cerevisiae, 4991 chicken erythroid cell protein, 4155 fgr Galactokinases erbB-2 human, 259 S. cerevisiae GAL3, 3439 mouse, 5570 p55c-fgr 259 Gamma-actin mRNA c-erbB-2 gene product y-Fibrinogen mouse, 2288 human adenocarcinoma MKN-7 cells, adenovirus major late promoter tran- Gapdh-l and Gapdh-2 1019 scription factor, 2628 D. melanogaster, 5200 phosphorylation CAAT-binding factor, 2628 Gastrin-releasing peptide precursor epidermal growth factor, 1019 Spl, 2628 human, 3129 tumor promoter, 1019 Fibroblast growth factor family GCN2 protein kinase ERCC2 novel growth factor with oncogenic po- S. cerevisiae, 2132 CHO UV5 cells, 1137 tential, 2933 transcription-translation, 2132 human, 1137 Fibroblast tropomyosin isoform 2 GCN3 Erythrocyte anion transport proteins cDNA, 5561 S. cerevisiae, 4808 chicken, 4416 mouse, 5561 GCN4 mRNA, 4416 Fibronectin binding S. cerevisiae, 2132 Erythroid anion transporter human, 4234 transcription-translation, 2132 chicken, 1327 transforming growth factor ,1, 4234 GCN4 mRNA Erythroid cell proteins FLP protein-promoted site-specific recom- S. cerevisiae, 3827 a-globin gene, 4270 bination translational control, 3827 Erythroid differentiation Holliday intermediates, 3784 Gene amplification chloramphenicol, 3311 reaction by-products, 3784 double minute chromosomes, 1525 mitochondrial protein synthesis, 3311 FLP recombinase episomes, 1525 mouse, 5545 step-arrest mutants, 3303 inverted duplication formation, 4302 mouse erythroleukemia cells, 3311 fluFl Gene conversion c-myc, 5545 A. nidulans, 3043 S. cerevisiae, 2442 Erythroid progenitor cell differentiation v-fmis Gene induction erythropoietin, 2604 mink, 176 2-aminopurine, 4289 mouse, 2604 NIH 3T3 cells, 176 dsRNA, 4289 Erythropoietin tyrosine phosphorylation associated with human, 4289 erythroid progenitor cell differentiation, transformation, 176 interferons, 4289 2604 c-fos Germ line immunoglobulin -y2b transcripts, mouse, 2604 human, 5521 1849 Escherichia coli human monocytes, 340 GLI-Kruppel family of human genes, 3104 groEL-encoded protein mouse, 5052 Glioblastomas mitochondrial homolog, 371 mRNA stability and transformation, epidermal growth factor, 1816 N. crassa methylated transforming human, 1816 DNA, 2211 5521 ESPI p21 v-ras, 5080 ,B-Globin S. cerevisiae, 5386 platelet-derived growth factor, 5052, mouse erythroleukemic cells, 3122 Estrogen receptor-binding sites 5080 mRNA chicken vitellogenin II gene, 5323 transcriptional activation human, 3244 Estrogen response elements calcium and growth factor pathways, stability determinants, 3244 chicken vitellogenin gene, 1123 2787 a-Globin gene Ethyl methanesulfonate-induced reversion rat, 2787 3-like gene expression, 5047 in mammalian cells, 4185 c-fos mRNA human, 5047 ets-2 protein human, 3244 ,B-Globin gene human, 4700 stability determinants, 3244 BFU-E cells, 1725 protein kinase C, 4700 fos protein DNA replication, 1301 eve proteins human, 2251 a-globin gene, 5047 D. melanogaster, 4598 osteogenesis, 2251 human, 5047 VOL . 8, 1988 SUBJECT INDEX xvii

mouse erythroleukemia cells, 1725 Granulocyte-macrophage colony-stimu- Heavy-chain enhancer X. laevis, 1301 lating factor promoter region mouse, 145 P-Globin gene human, 1979 HeLa cells chicken, 5369 Group II intron domain 5 adenovirus infected, 1534 transcription termination, 5369 trans-splicing reaction, 2361 EIA expression, 4799 ,-Globin gene domain Growth factors enzyme fraction that cleaves DNA at human, 4958 mouse, 2140 poly(G) sequences, 2513 replication, 4958 Growth hormone HI histone gene-specific factor y-Globin gene promoter human, 2011 binding, 4576 human, 5310 pre-mRNA, 2011 IVa2 promoters nuclear protein binding GRP78 footprinting, 1534 HPFH-associated point mutations, A2318, 4579 low-molecular-weight heat shock pro- 5310 CHO cells, 4063 tein, 5059 Globin genes hamster, 4250 major late promoters human, 4917 human, 4579 footprinting, 1534 P-Globin intervening sequence 2 immunoglobulin heavy-chain-binding pOTC mutants mouse, 381 protein, 4250 mitochondrial import, 5150 tissue-specific DNA-binding proteins, protein secretion, 4063 pre-mRNA primary structure, 2884 381 rat, 4579 ribonucleoprotein, 2884 1-Globin pre-mRNA GTP hydrolysis TATA box transcription factor activa- human, 4484 ras (mutated) proteins, 2472 tion by EIA, 1765 intron Guanine nucleotide exchange Hematopoietic growth factors donor site sequences, 4484 RAS (mutated) proteins, 2472 mouse, 2214 a-Globin promoter-binding proteins, 4270 Gus-s' allele tyrosine phosphorylation of proteins, mouse, 3215 mouse 3-glucuronidase gene, 1160 2214 Glucagon expression Hematopoietic stem cells pancreatic islet cells, 4877 HI histone gene-specific factor mouse stromal cell lines, 3864 Glucocorticoid response elements binding retrovirus vectors encoding SV40 large mouse mammary tumor virus, 3872 HI gene transcription, 4576 T antigen, 3864 phosphoenolpyruvate carboxykinase chicken, 4576 Heme gene, 96 HeLa, 4576 S. cerevisiae COXSa and COX5b, 4537 rat, 96 H19 gene Hepatic trans-acting factors transcription, 3872 mouse, 4707 alpha-l-antitrypsin gene transcription, Glucocorticoids regulatory domains, 4707 4362 amylase mRNA regulation, 3857 Hamster human, 4362 liver maturation, 203 GRP78, 4250 Hepatitis B virus mouse, 3857 immunoglobulin heavy-chain-binding enhancer and core promoter domains rat, 203 protein, 4250 protein-binding sites, 5159 rat hepatoma cell variants, 1449 insulin gene transcription control region, S promoter regulation, 2449 tumor cell growth, 1449 2620 Hepatocytes Glucose HAP2 mouse, 3338 human, 393 S. cerevisiae COX5a and COX5b, 4537 tissue-specific gene expression, 3338 Glucose transport HAP3 Hepatocyte-stimulating factor chicken, 138 S. cerevisiae, 655 rat a,-acid glycoprotein gene, 42 rat, 138 Heat shock Hepatoma-specific nuclear factor src, 138 D. discoideum, 153 albumin genes, 5179 Glutamine synthetase D. melanogaster, 91, 3550 a-fetoprotein genes, 5179 mouse, 4966 heat shock, 3837 human, 5179 Glyceraldehyde-3-phosphate dehydroge- human, 393 Herpes simplex virus nase genes protection DNA replication D. melanogaster, 5200 D. melanogaster cold stress, 3550 rabbit skin cells, 3272 Glycolipid anchors ribosome synthesis, 91 Vero monkey cells, 3272 Thy-i - mutant thymoma cells, 674 S. cerevisiae, 5555 DNA replication origin, 4018 Glycoprotein T. brucei, 3837 human hypoxanthine-guanine phosphori- mouse brain, 2655 Heat shock element-binding activity bosyltransferase gene transferred myelin-associated, 2655 HSP70, 4736 into neuronal cells, 457 Glycoprotein CD4 human, 4736 hypomethylation of DNA synthesis, mouse, 2224 Heat shock factor 1443 Glycoprotein hormone alpha-subunit gene binding to DNA, 5040 rat, 1443 human, 5470 S. cerevisiae, 5040 tk expression mouse, 5470 Heat shock protein mouse, 1336 Glycoprotein transport changes in structure and locale, 5059 satellite DNA, 1336 mouse, 833 E. coli, 1206 Heterogeneous nuclear ribonucleoprotein Gmhsp26-A HeLa cells, 5059 complexes soybean, 1113 mouse plasmacytoma C proteins bind polyadenylation sub- Granulocyte-macrophage colony-stimu- theromoresistance, 5486 strates, 4477 lating factor mouse spermatogenic cells, 3260 Heterogeneous nuclear ribonucleoprotein activation p53 complexes, 1206 particles human T-cell leukemia virus type I- rat, 1206 proteins, 2237 encoded p4Ox protein, 5581 thermoresistance, 5486 High-mobility-group-like DNA-binding pro- T-cell activation signals, 5581 Heat shock regulatory elements tein mouse, 5581 D. melanogaster, 3761 rRNA synthesis, 3406 xviii SUBJECT INDEX MOL. CELL. BIOL. his3 recombinational substrates a-actin promoter, 4110 fibroblast tropomyosin isoform 3, 160 chromosome rearrangements, 4370 actin synthesis, 1790 "finger"-containing gene encoded by 5' S. cerevisiae, 4370 adeno-associated virus, 2513 half of the ret transforming gene, HIS4 adenocarcinoma MKN-7 cells 1853 S. cerevisiae, 2955, 2964 c-erbB-2 gene product, 1019 c-fos Histocompatibility complex class I gene adenosine deaminase expressed in monocytes, 340 mouse B16 melanoma rejection, 1857 mouse cells, 5116 c-fos mRNA stability and transforma- Histone gene promoters Ay nondeletion hereditary persistence of tion, 5521 X. laevis, 3676 fetal hemoglobin, 713 fos protein, 2251 Histone gene switching albumin genes c-fos RNA, 3244 mouse, 4406 hepatoma-specific nuclear factor, 5179 c-fpslfes gene product expressed in rat Histone genes alpha-l-antitrypsin gene transcription, fibroblasts, 578 CHO cells, 1887 4362 gastric carcinoma tyrosine kinase, 3510 differential expression, 1887 al(I) collagen gene gastrin-releasing peptide precursor, 3129 sea urchin, 1236 transcriptional control, 4851 gene induction X. laevis oocytes, 1236 alphoid DNA transfected into Chinese 2-aminopurine, 4289 Histone H5 genes hamster genomes, 3611 dsRNA, 4289 avian cells, 1657 amylase gene evolution, 1197 interferons, 4289 replication polarities, 1657 apoAl gene GLI-Kruppel family of genes, 3104 Histone pre-mRNA processing cis-acting regulatory elements, 605 glioblastomas mouse, 1518 apo-B gene epidermal growth factor, 1816 U7 small nuclear RNA, 1518 chromatin structure, 71 1-globin gene, 5047 Histone RNA basic fibroblast growth factor cDNA, BFU-E cells, 1725 S. cerevisiae, 945 588 mouse erythroleukemia cells, 1725 HL60 cells BCRIABL ,B-globin gene domain anti-myc oligomer, 963 lymphoid and myeloid culture trans- coordinate replication, 4958 differentiation, 963 formation, 4079 a-globin gene inhibits 3-like gene human, 963 cachectin/tumor necrosis factor expression, 5047 c-myc, 867 lipoprotein lipase gene expression in -y-globin gene promoter HLA class II genes mouse adipocytes, 2394 nuclear protein binding, 5310 transcription in absence of B-cell-specifi- calcium-binding protein gene expression, globin genes, 4917 c octamer-binding factor, 3734 2402 1-globin mRNA, 3244 HMGI-like protein cardiac actin gene 13-globin pre-mRNA S. cerevisiae ACP2 gene, 1282 mouse embryonal carcinoma cells, 406 donor site sequences inserted in in- HO endonuclease cDNA tron, 4484 chromosomal breaks, 3918 colony-stimulating factor I precursors, glucogon expression, 4877 S. cerevisiae, 3918 5026 glucose-responsive cells, 393 Holliday intermediates cDNA expression, 2837 glycoprotein hormone alpha-subunit FLP protein-promoted site-specific re- chorionic gonadotropin 1B subunit gene gene in mice, 5470 combination, 3784 cluster, 5100 granulocyte-macrophage colony-stimu- HPFH-associated point mutations chromosome 17, 722 lating factor promoter region, 1979 -y-globin gene promoter chromosome instability and alphoid growth hormone, 2011 nuclear protein binding, 5310 DNA, 3611 GRP78, 393 human, 5310 class III transcription factors, 3017 GRP78 transcription, 4579 H-region amplification colony-stimulating factor 1 precursors, heat shock, 393 L. major, 5188 5026 heat shock element-binding activity, L. tarentolae, 5188 CSF-I regulation, 3951 4736 hsp58 cytoskeletal actin genes, 1790 heat shock protein, 5059 S. cerevisiae, 371 DNA adduct removal, 3964 HeLa cell enzyme fraction T. thermophila, 371 DNA polymerase a, 5016 DNA cleavage, 2513 X. laevis, 371 DNA repair, 5331 hepatic trans-acting factors, 4362 Z. mays, 371 downstream exon, 860 hepatocellular carcinoma-derived cell hsp68 EIA expression, 4799 lines, 25 mouse plasmacytoma, 5486 enzyme fraction that cleaves DNA at hepatoma-specific nuclear factor thermoresistance, 5486 poly(G) sequences, 2513 albumin genes, 5179 HSP70 epidermal growth factor, 1816 a-fetoprotein genes, 5179 heat shock element-binding activity, epidermal growth factor receptor, 25, HL60 cells 4736 1345, 5477 anti-myc oligomer, 963 human, 4736 epidermal growth factor receptor gene, c-myc, 867 mouse, 2925 4561 HLA class II genes mouse erythroleukemic cell differentia- epidermal growth factor receptor pro- transcription, 3734 tion, 2219 moter SI nuclease sensitivity, 4174 HSP70, 393 S. cerevisiae transcription mutants, 3423 Epstein-Barr virus shuttle vector, 2837 HSP70 transcription rates, 4736 transcription rates, 4736 ERCC2, 1137 hTMa expression, 433 hTMa erythroleukemia cells, 4917 3-hydroxy-3-methylglutaryl coenzyme A human, 433 ets-2 protein stabilization, 4700 reductase, 3797 Human fetal globin gene mutation in Ay nondele- hypoxanthine-guanine phosphoribosyl- 4F2HC gene, 3809, 3820 tion hereditary persistence of fetal transferase gene, 457 A431 cells, 1345 hemoglobin, 713 immunoglobulin K gene, 511 B-actin enhancer, 267 a-fetoprotein genes initiation factor eIF-2 y-actin gene, 1775 hepatoma-specific nuclear factor, 5179 mutant form, 993 a-actin gene transcription FGF-5 oncogene, 3487 interleukin 2 trans-acting factor, 4120 fgr proto-oncogene product p55c-fgr, 259 antigen receptor response elements, VOL . 8, 1988 SUBJECT INDEX xix

1715 prostatic phosphotyrosyl phosphatase, 1186 interleukin-la 5477 Initiation factor eIF-2 lipoprotein lipase gene expression in protein kinase C, 4700 human, 993 mouse adipocytes, 2394 ras proteins (mutated) mutant form, 993 K gene, 511 GTP hydrolysis, 2472 Inositol keratin 18 gene guanine nucleotide exchange, 2472 phosphatidylglycerolphosphate synthase mouse, 1540 transforming potential, 2472 expression, 4773 keratin genes, 722 retinoblastoma tumors S. cerevisiae, 4773 keratin K5, 486 RBI gene, 2082 Insertion element RlBm keratinocytes retinoic acid-induced differentiation, B. mori, 114 gene families, 2195 1677 non-long-terminal repeat retrotranspo- protein, 2204 retrovirus, 974 son, 114 low-molecular-weight heat shock pro- RNA polymerase II Insulin II gene tein, 5059 transcription elongation factor SII, COUP transcription factor, 2070 macrophage colony-stimulating factor in 3136 rat, 2070 mouse cells, 5035 c-sis overexpression and anchorage inde- Insulin gene metallothionein genes pendence, 2089 hamster, 2620 DNA repair, 5331 SRa promoter, 466 transcription control region binding, microfilament protein composition, 1790 T-cell leukemia virus type I-encoded 2620 mitochondrial transcription factor 1, p40X protein Insulin receptor 3496 mouse granulocyte-macrophage colo- D. melanogaster, 1638 mitochondrial transcription termination, ny-stimulating factor gene, 5581 Integral membrane proteins 4502 teratocarcinoma cells actin microfilaments, 564 monocytes unit-length Line-I transcripts, 1385 chicken, 564 c-fos, 340 thrombomodulin gene, 5588 integrin p-chain, 564 c-myb, 1677 thymidine kinase gene, 1551 P. falciparum, 1709 N-myc amplification units, 522 T-lymphocyte activation, 3809, 3820 peptide sequence transport to cell sur- c-myc, 124, 4389 transforming growth factor alpha pro- face, 1709 polyomavirus middle-T-antigen gene, moter, 5549 respiratory syncytial virus glycoprotein 2261 triosephosphate isomerase mRNA degra- G, 1709 rat, 2261 dation, 802 Integrin ,B-chain L-myc, 186 tropomyosin isoform 3, 160 actin microfilaments, 564 c-myc protein tumor necrosis factor, 2295, 5588 chicken, 564 nuclear translocation signal, 4048 U2 small nuclear RNA membrane protein antigen, 564 L-myc proteins, 4381 adenovirus type 12 infection, 1863 Interferon c-myc RNA fragile site, 1863 mouse, 3065 poly(A) loss and degradation, 1697 X-CGD expression, 2804 Mx promoter, 3065 myeloid differentiation, 2402 Human immunodeficiency virus I and 2 c-myc, 2828 myeloid leukemic blast stem cells, 974 trans-activating element, 2555 a-Interferon neo, 974 Human nerve growth factor receptors SV40 T antigen, 3397 nerve growth factor receptor gene, 3160 X. Iaevis oocytes, 2242 type I nerve growth factor receptors in X. 3-Hydroxy-3-methylglutaryl coenzyme A trans activation of promoters by SV40 laevis oocytes, 2242 reductase T antigen, 3397 neuroblastoma cell differentiation D. melanogaster, 2713 R2 Interferon DNA adduct removal, 3964 human, 3797 a,-acid glycoprotein gene, 42 neuroblastoma cells, 522 S. cerevisiae, 3797 rat, 42 1-nitrosopyrene adducts, 3364 Hypermethylation Interleukin ornithine transcarbamylase expressed in T. thermophila, 1664 mouse, 2214 mouse testes, 1821 Hypoxanthine-guanine phosphoribosyl- tyrosine phosphorylation of proteins, ornithine transcarbamylase precursors transferase 2214 mitochondrial import, 5150 HSV-mediated gene transfer into neuro- Interleukin I processing, 5150 nal cells, 457 a,-acid glycoprotein gene, 42 osteogenesis, 2251 human, 457 rat, 42 p92c-fes, 578 Interleukin 2 p145 protein, 3510 Immunoglobulin antigen receptor response elements, 1715 phosphoglycerate kinase gene, 4692 heavy-chain enhancer CHO cells, 3357 pim-1 gene product, 1498 B-cell specificity, 988 human, 1715 plasma cell myeloma Immunoglobulin A degradation 0-linked carbohydrate-deficient recep- c-myc, 124 a heavy-chain glycosylation, 4197 tors plastin, 4659 mouse, 4197 missorting, 3357 platelet-derived growth factor Immunoglobulin H Interleukin 6 A-chain cDNA, 571 B-cell stimulatory factor 2, 3546 gene, 571 gene expression, 1932 platelet-derived growth factor 2, 2089 mouse, 1932 PC12 cells platelet-derived growth factor homodi- Immunoglobulin heavy-chain-binding pro- neuronal differentiation, 3546 mers, 2753 tein Interleukin-1oa platelet-derived growth factor receptor, GRP78, 4250 lipoprotein lipase gene, 2394 3476 hamster, 4250 Intracisternal A-particle genes polyomavirus BK enhancer, 3448 Immunoglobulin K genes long terminal repeats, 1093 pOTC mutants human B lymphocytes, 511 mouse, 1093 mitochondrial import, 5150 mouse, 4041 Intron 5 pre-mRNA, 2011 Influenza B virus NB cob gene pre-mRNA splicing, 860, 4484 polylactosaminoglycan modification, S. cerevisiae, 2562 xx SUBJECT INDEX MOL. CELL. BIOL.

Intron-dependent and -independent gene differentiation, 1414 Major urinary protein expression expression junction formation, 1414 mouse, 2705 rabbit, 4395 pp60vsrc, 1414 mak Inverted duplication formation, 4302 LEU3 M, virus, 938 Iso-l-cytochrome c gene branched-chain amino acid biosynthesis, S. cerevisiae, 938 S. cerevisiae, 1045 2690 suppression by L-A dsRNA variant, 938 IVa2 promoters multiple gene activation, 2690 MAL63 adenovirus-infected HeLa cells, 1534 S. cerevisiae, 2690 S. cerevisiae, 1027 footprinting, 1534 Lewis lung carcinoma cells MAL64-C tropomyosin isoform, 3934 S. cerevisiae, 1027 Japanese quail L-factor DNA as a plasmid Malarial merozoite myogenesis, 4134 mouse F9 cells, 2097 surface antigen troponin complex gene expression, 4134 Line- I third form, 2664 unit-length transcripts in human terato- Malic enzyme gene promoter K gene carcinoma cells, 1385 rat, 3542 human B lymphocytes, 511 LINES ONE sequences Maltose fermentative enzymes K immunoglobulin genes M. caroli and M. domesticus 0-globin S. cerevisiae, 1027 enhancer activity, 930 loci, 4669 Mammalian cells hypomethylation, 930 movement, 4669 nerve growth factor, 2456 mouse, 930 Lipoprotein lipase gene RNA duplex unwindase, 770 K-Immunoglobulin precursor mRNA human cachectin/tumor necrosis factor, Mating factor signaling pathway splice site selection, 2610 2394 GPAI, 3777 Karyoskeletal protein-enriched fractions human interleukin-la, 2394 S. cerevisiae, 3777 from Saccharomyces cerevisiae mouse, 2394 STE genes, 3777 thermal stabilization, 4573 Liposomes Mating pheromone signaling Keratin 18 gene pp6 v-src 1896 G protein human, 1540 Liver maturation a subunit gene, 2484 mouse, 1540 glucocorticoids, 203 S. cerevisiae, 2484 Keratin genes rat, 203 Mating type switching human chromosome 17, 722 Long terminal repeats physical monitoring, 2342 Keratin K5 DNA binding, 5232 S. cerevisiae, 2342 human epidermal cells, 486 intracisternal A-particle genes, 1093 Mating-factor signaling pathway Keratinocytes mouse, 1093 S. cerevisiae, 5410 calcium signal for terminal differentia- mouse mammary tumor virus, 473 SGP2, 5410 tion, 557 reticuloendotheliosis virus, 5232 Matrix attachment regions epidermal growth factor, 557 transcriptional elements, 5232 Chinese hamster ovary cells, 5398 gene families, 2195 Loop I of small nuclear RNA dihydrofolate reductase domain, 5398 human, 2195, 2204 protein binding, 4787 mdr gene family mouse, 557 Ly-5 mouse, 2770 protein, 2204 mouse, 4889 Meiotic recombination Keratoacanthomas Lymphoid specificity S. cerevisiae animal models, 786 dispersed repeats, 2942 v-abl tyrosine kinase region, 234 Membrane humans, 786 v-src tyrosine kinase region, 234 H-ras, 786 actin microfilaments, 564 Lysine 7 chicken, 564 K-FGF, 2933 2435 c-kit pp60v-src myristylation, integrin p-chain, 564 cat, 4896 Lytechinus pictus protein antigen, 564 Kluyveromyces lactis tubulin mRNA, 3518 Membrane protein gene DNA-binding domain of a regulatory cold shock, 153 protein, 3726 M, virus D. discoideum, 153 mak suppression by L-A dsRNA vari- heat shock, 153 L2 ribosomal protein genes ant, 938 Membrane translocation gene disruptions, 4792 S. cerevisiae, 938 a-factor, 1915 S. cerevisiae, 4792 Macrophage colony-stimulating factor S. cerevisiae, 1915 LAC9 protein human, 5035 Merozoite surface antigens DNA-binding domain, 3726 mouse, 5035 P. falciparum, 2664 K. lactis, 3726 Madin-Darby canine kidney cells Metallothionein B gene Large T antigen pp6csrc 632 rainbow trout, 4469 adipocyte differentiation, 1380 Major excreted protein Metallothionein genes mouse, 1308 ACEI, 2745 mouse, 3316 DNA repair, 5331 SV40, 1380 Major histocompatibility complex human, 5331 Late histone subtype HI-I gene mouse S. cerevisiae, 2745 S. purpuratus, 1842 Kb mutants, 4342 Metallothionein I Ick Major histocompatibility complex class II Chinese hamster cells, 4716 mouse, 3058 gene Metallothionein II Leishmania enriettii B lymphocytes, 3975 Chinese hamster cells, 4716 ribonucleoprotein complexes, 2597 protein binding, 2034 Metastasis trans splicing, 2597 rabbit, 2034 mouse, 2078 Leishmania tarentolae Major late promoters p53, 2078 H-region amplification, 5188 adenovirus-infected HeLa cells, 1534 Methotrexate resistance Lens cells footprinting, 1534 CHO cells, 2822 chicken embryo, 1414 SV40, 2021 cycloheximide, 2822 VOL. 8, 1988 SUBJECT INDEX xxi

Methylated transforming DNA 1-actin gene a-globin promoter-binding proteins, 3215 E. coli, 2211 5' sequences, 480 glucocorticoid, 3857 N. crassa, 2211 adenosine deaminase, 5116 ,B-glucuronidase gene 7-Methylguanosine adenovirus ElA-like activity, 3553 Gus-sa allele, 1160 mRNA cap, 494 adipocyte differentiation, 1380 glutamine synthetase expression, 4966 T. brucei, 494 AKXD myeloid tumor glycoprotein Middle-T antigen Evi-I integration site, 301 myelin-associated, 2655 polyomavirus, 1736 al-antitrypsin gene enhancer, 1055 glycoprotein CD4, 2224 pp60c-src carboxy terminus, 1736 a heavy-chain glycosylation, 4197 glycoprotein transport, 833 Middle-T-antigen gene amylase mRNA regulation, 3857 granulocyte-macrophage colony-stimu- human c-myc oncogene, 2261 amyloid A gene expression, 3710 lating factor gene polyomavirus, 2261 androgen-inducible sequences, 2117 human T-cell leukemia virus type I- rat, 2261 B16 melanoma rejection, 1857 encoded p4Ox protein, 5581 Milk protein gene expression B lymphocyte stimulation T-cell activation signals, 5581 cell substratum regulation, 3183 anti-immunoglobulin antibody, 1371 growth factors, 2140 hormonal regulation, 3183 cytochalasin, 1371 H19 gene regulatory domains, 4707 mammary epithelial cells, 3183 BALB/c 373 cells transformed with hu- haploid-specific transcription, 1748 Mink man basic fibroblast growth factor heat shock proteins, 3260 cellular mutant refractory to transforma- cDNA, 588 heavy-chain enhancer, 145 tion, 2419 Ca2+-mobilizing system hematopoietic growth factors, 2214 v-fms, 176 desensitization to serum growth fac- hematopoietic stem cell proliferation, tyrosine phosphorylation, 176 tors, 4212 3864 Mitochondria carcinogens, 1% histocompatibility complex class I gene, human ornithine transcarbamylase pre- cardiac actin gene, 406 1857 cursors, 5150 cDNA, 5561 histone gene switching, 4406 Mitochondrial DNA cellular determination histone pre-mRNA processing, 1518 Ogura radish, 1474 oncogenic transformation, 4322 homology requirements for recombina- T. malaccensis, 4450 chloramphenicol, 3311 tion, 5350 telomeric repeats chromosomal loci active in embryonal HSP70, 2219 multimodal distribution, 4450 carcinoma stem cells, 3251 HSP70 gene family, 2925 X. laevis, 2917 cis effects of c-myc mRNA 5' region, hsp70-like protein in spermatogenic Mitochondrial homolog 2875 cells, 828 E. coli groEL-encoded protein, 371 colony-stimulating factor I receptor HSV tk gene expression Mitochondrial RNA polymerase tyrosine kinase activity, 1795 satellite DNA, 1336 transcription, 2910 cytoskeletal actin mRNA expression, human adenosine deaminase, 5116 X. laevis, 2910 3929 human basic fibroblast growth factor Mitochondrial transcription factor I cytoskeletal -y-actin cDNA, 588 human, 3496 cDNA clones, 3929 human cardiac actin gene, 406 Mitochondrial transcription termination DNA-binding factors of B lymphoid human glycoprotein hormone alpha-sub- human, 4502 cells, 1812 unit gene, 5470 tridecamer DNA sequence, 4502 EJ-ras, 5052 human keratin 18 gene, 1540 Mitogenic blocks embryonal carcinoma cells, 406 human macrophage colony-stimulating epidermal growth factor, 2302 embryonal carcinoma stem cells, 3251 factor, 5035 tumor promoter phorbol ester, 2302 enhancer-binding proteins in lympho- human ornithine transcarbamylase, 1821 Mitomycin C cytes, 1625 immunoglobulin A degradation, 4197 monkey cells, 3943 epidermal growth factor, 497, 557, 2247 immunoglobulin H enhancer and pro- Molecular karyotype ERA-I moter, 1932 N. crassa, 1469 homeobox domain, 3906 immunoglobulin K genes, 4041 Monkey erbB-2, 5570 inhibitory mutant ras protein, 3235 camptothecin, 3026 erythroid differentiation, 5545 interferon, 3065 DNA breakage, 3026 erythroid progenitor cell differentiation, interferon-regulated Mx gene, 4524 DNA replication, 3272 2604 K immunoglobulin genes, 930 herpes simplex virus, 3272 erythroleukemia cell differentiation, Kb mutants, 4342 mitomycin C treatment, 3943 2219, 3311 keratin 18 gene, 1540 p53-hsp72n3 (mutant) protein-protein erythroleukemia cells keratinocytes, 557 complexes, 3740 globin-inducing trans-acting factors, transforming growth factor 1, 3088 SV40, 3026 130 K-FGF, 2933 SV40 oncoprotein, 5495 erythropoietin, 2604 Ick gene, 3058 SV40 origin binding protein, 903 Evi-I integration site, 301 L-factor DNA as a plasmid, 2097 UV-damaged SV40 DNA replication, a-fetoprotein gene enhancers, 1169 LINES ONE sequence movement, 4669 2428 fibroblast tropomyosin isoform 2, 5561 lipoprotein lipase gene expression, 2394 mos fibroblasts that overexpress pp60cs Ly-S, 4889 chicken homolog of proto-oncogene, 923 497 lymphocytes, 1625 v-mos c-fos, 5052 macrophage colony-stimulating factor, CHO cells, 4685 GI progression, 3683 5035 Mouse gamma-actin mRNA, 2288 major excreted protein, 3316 5' sequences 1-globin intervening sequence 2 major histocompatibility complex class cycloheximide-dependent regulation, tissue-specific DNA-binding proteins, II gene 480 381 B lymphocytes, 3975 serum-dependent regulation, 480 1-globin loci major urinary protein expression, 2705 c-abl mRNAs, 4547 LINES ONE sequence movement, mammary tumor virus acetylcholine receptor 8- and -y-subunit 4669 glucocorticoid response element re- gene activation, 5257 1-globin promoter, 3122 presses transcription, 3872 xxii SUBJECT INDEX MOL. CELL. BIOL.

mdr gene family, 2770 transmembrane signalling, 5448 mRNA function metastasis, 2078 T-cell receptor alpha-chain genes, 5459 leader length, 2737 mitochondrial protein synthesis inhibi- testicular a tubulin secondary structure, 2737 tors, 3311 divergent form, 996 translation, 2737 mRNA synthesis, 2117 Thy-l transcriptional unit, 3847 mRNA-decapping enzyme ,uEBP-E binding to immunoglobulin en- thymidine kinase gene, 3298 S. cerevisiae, 2005 hancers and promoters, 4972 thymidine kinase gene expression, 5280 MRP7 Mup promoter-thymidine kinase reporter TIMP gene S. cerevisiae, 3636 gene, 4821 transcription regulatory elements in MRP13 muscle creatine kinase gene, 62, 28% intron, 3227 S. cerevisiae, 3647 mutation induction TIS gene expression, 4570 ,uEBP-E N4-aminocytidine-mediated replica- tissue-specific gene expression in hepa- binding to immunoglobulin enhancers tional errors, 347 tocytes, 3338 and promoters, 4972 Mx gene, 3065, 4524 trans-acting factors, 130 mouse, 4972 Mx- genes, 4518 transformation-defective variant, 4190 Multigene families c-myb mRNA, 3938 transforming growth factor ,3, 3088 mammalian cells, 2149 c-myc antisense transcripts, 3683 transforming growth factors a and , replication, 2149 c-myc, 3938, 5545 3415 Mup promoter-thymidine kinase reporter myelin-associated glycoprotein, 2655 transthyretin gene enhancer, 81 gene NF-KB-binding site in nonlymphoid troponin I gene, 5072 mouse, 4821 cells, 3526 TTFI, 3891 Muscle creatine kinase gene oncogenic transformation tumorigenesis, 3382 enhancer, 62 cellular determination, 4322 tyrosine kinase, 5541, 5570 mouse, 62, 28% p21 GTPase stimulatory factor, 4169 tyrosine phosphorylation of proteins, regulatory elements, 2896 p53 increases metastasis, 2078 2214 MuSVtsl 1O pS6Ick, 3560, 4353 U7 small nuclear RNA, 1518 pre-mRNA splicing, 1558 p60c-src, 3560 viral integration site, 301 Mx platelet-derived growth factor, 5052 VL30 element, 2247 interferon regulation, 4524 polyomavirus middle T antigen, 2309 VL30 retro-element, 2989 mouse, 3065, 4518, 4524 pp60c-src, 502 zinc fingers promoter, 3065 prealbumin gene enhancer, 81 multigene family that encodes, 1319 c-myb prion gene complex, 5528 Mouse mammary tumor virus cDNA expression, 884 promoterless thymidine kinase gene, glucocorticoid response element Friend murine erythroleukemia cell dif- 3298 represses transcription, 3872 ferentiation, 884 protamine-myc, 1748 glycoproteins human neuroblastoma cells, 1677 protamine-T-antigen fusion gene, 1748 variant mouse lymphoma cell line, 833 c-myb mRNA protein kinase C, 5448 long terminal repeat mouse, 3938 protein kinase C activator, 2247 multiple regulatory domains, 473 c-myb protein degradation pseudogene retroposition and growth mRNA heat shock, 2504 regulation, 2797 3'-end formation metabolic inhibitors, 2504 quail troponin I gene, 5072 S. cerevisiae, 1045 myc B-raf, 2651 adenovirus region E3, 3291 small-cell lung cancer ras mutant protein, 3235 androgen-inducible sequences, 2117 transcriptional regulation, 3373 K-ras point mutations, 2233 D. discoideum, 1957 B-myc N-ras point mutations, 2233 decay rate rat, 3168 rat myosin light-chain 2 gene, 1006 D. discoideum, 4088 c-myc recombination elongation factor Tu 3T3-L1 cells, 1614 carcinogen induced, 1% Friend erythroleukemia cells, 1085 antisense transcripts homology requirements, 5350 erythrocyte anion transport proteins, G, progression, 3683 retinoic acid, 3906 4416 mouse, 3683 retrovirus SL3-3, 1625 chicken, 4416 avian leukosis virus-induced B-cell lym- retrovirus vectors used to tag tumor flagellar mRNA phomas, 2659 cells, 3143 N. gruberi, 2280 cell differentiation, 1614 ribonucleotide reductase Ml, 2698 hvl, 4780 erythroid differentiation, 5545 ribosomal DNA transcription, 3891 7-methylguanosine cap, 494 GOGI transition gene expression, 3080 ribosomal protein S6, 2309 mouse, 2117 HL60 cells, 867 RNA polymerase I1 N. gruberi flagella, 2280 human, 2261, 4389 carboxyl-terminal domain, 330 rat intestinal mucosa, 4243 human plasma cell myeloma, 124 scrapie incubation time, 5528 S. cerevisiae, 1591 interferon resistance, 2828 sex-limited protein S. cerevisiae histone H3-H4 loci, 945 mouse, 3938, 5545 hormonal regulation, 2350 surface protein, 427 p21 v-ras, 5080 spermatogenic cells, 828 synthesis rates platelet-derived growth factor, 5080 heat shock proteins, 3260 mouse kidney, 2117 polyomavirus middle-T-antigen gene, stromal cell lines supporting hematopoi- T. brucei, 494 2261 etic stem cell proliferation, 3864 T. thermophila, 4780 rat, 441, 2261 Surfeit locus T. thermophila surface protein, 427 t(6;7) chromosomal translocation, 441 clustered genes, 3898 translation, 1591 transcription termination, 4389 SV40 large-T antigen, 1380 poliovirus, 1103 transcriptional regulation, 867 SV40 oncoprotein, 5495 tubulin translocation disrupts regulation, 124 SV40 small tumor antigen, 3382 L. pictus embryo, 3518 L-myc T-cell activation, 4353 protein synthesis, 3518 alternative mRNA processing, 186 T-cell antigen receptor mRNA cap-binding protein eIF-4E human, 186 protein kinase C, 5448 S. cerevisiae CDC33, 3556 proteins VOL. 8, 1988 SUBJECT INDEX xxiii

human, 4381 Neuronal cells otu ras, 2668 human hypoxanthine-guanine phosphori- D. melanogaster, 1481 rat fibroblast transformation, 2668 bosyltransferase gene, 457 c-myc mRNA Neuronal differentiation p16 human, 1697 B-cell stimulatory factor 2/interleukin 6, rRNA synthesis, 3406 poly(A) loss and degradation, 1697 3546 p21 GTPase stimulatory factor stability in cell-free system, 2860 PC12 cells, 3546 mouse, 4169 N-myc Neurospora crassa p21 v-ras amplification units, 522 chromosomal DNA, 1469 c-fos expression, 5080 human neuroblastoma cells, 522 con-10, 2411 c-myc expression, 5080 c-myc protein cys-14+, 1504 platelet-derived growth factor, 5080 human, 4048 methylated transforming DNA p21-ras effector domain mutants nuclear translocation signal, 4048 E. coli, 2211 "cassette" mutagenesis, 3565 c-myc protein degradation molecular karyotype, 1469 p2lv-ras heat shock, 2504 nuc-1, 1376 myristylation, 3960 metabolic inhibitors, 2504 phosphate permease, 1376 p60src, 3960 N-myc:,B-galactosidase fusion proteins phosphorus-repressible phosphate per- p53 antitransforming activity, 4529 mease, 1376 complexes, 1206 subnuclear localization, 4529 sulfur regulatory circuit, 1504 metastasis, 2078 Myelin-associated glycoprotein van, 1376 mouse, 2078 mouse brain, 2655 Neurotransmitter gene transcriptional regu- phosphorylation in normal and SV40- phosphorylation, 2655 lation transformed NIH 3T3 cells, 461 Myeloid colony-stimulating factor cAMP, 4225 transformation tumor necrosis factor, 3432 trans-acting factor, 4225 gene product of mutations, 531 Myeloid differentiation NF-KB-binding site p53-hsp72/73 (mutant) protein-protein com- calcium-binding protein gene expression, mouse, 3526 plexes, 3740 2402 Nicotiana tabacum p55c-fgr human, 2402 pre-mRNA processing, 2042 fgr, 259 Myoblasts NIH 3T3 cells human, 259 rat, 2335 v-fms transformation, 176 p561ck temperature sensitive for differentiation, p53 phosphorylation, 461 mouse, 3560 2335 pp60c-sc transformation, 704 p60c-src regulation, 3560 Myosin ras mutant protein, 3235 T-cell activation, 4353 D. discoideum, 794 v-src/c-src chimeras, 704 p60c-src Myosin light-chain l/3f gene tyrosine phosphorylation, 176 mouse, 3560 I kb of sequence 5' to the start sites, I-Nitrosopyrene adducts regulation by carboxy-terminal sequence 1361 human cells, 3364 of p56 ck, 3560 chicken, 1361 Non-AUG codons p6fsrc Myosin light-chain 2 gene translation initiation in S. cerevisiae, p2lv-ras myristylation, 3960 mouse, 1006 4533 p6Ov-src rat, 1006 Nonerythroid a-spectrin genes 78-kilodalton glucose-regulated protein, Myosin light-chain genes homology among diverse species, I 2675 Nonessential disulfide bonds CEF, 2675 C. elegans, 5339 P70 Myristylation v-sis protein, 1011 mouse spermatogenic cells, 828 lysine 7, 2435 nuc-l p75 p60v-src 4295 N. crassa, 1376 D. melanogaster, 1877 pp60v-src, 2435 van, 1376 p92c-fes Nuclear development human, 578 Naegleria gruberi T. thermophila, 2681 rat, 578 flagellar mRNA, 2280 Nuclear DNA synthesis p145 NB Chinese hamster cells, 1923 human gastric carcinoma tyrosine ki- influenza B virus, 1186 replication forks, 1923 nase, 3510 polylactosaminoglycans, 1186 Nucleosomal templates pl85neu neo RNA polymerase II preinitiation com- tyrosine phosphorylation, 3969 human myeloid leukemic blast stem plexes, 3114 Pancreatic islet cells cells, 974 transcription initiation, 3114 glucagon expression, 4877 Neoplastic transformation Pappillomavirus pp56Ick, 540 Ogura radish E5 transforming protein, 4071 Nerve growth factor mitochondrial DNA, 1474 Paramecium tetraurelia chicken, 452 Opsin expression teleomere, 251 COS cells, 452 rat retina, 1570 telomerelike sequences, 4765 mammalian cells, 2456 Origin of replication PC12 cells rat, 452 SV40 B-cell stimulatory factor 2/interleukin 6, Nerve growth factor receptor gene monkey cells, 903 3546 human, 3160 Ornithine decarboxylase neuronal differentiation, 3546 Nerve growth factor receptors CHO cells, 764 Pea chloroplast DNA human, 2242 Orychophragmus violaceus replication origins, 1216 X. laevis, 2242 pre-mRNA processing, 2042 P-element-induced vg mutants Neuroblastoma cells Osteogenesis D. melanogaster, 1489 human, 522 fos protein, 2251 Peptide sequence N-myc amplification units, 522 human, 2251 P. falciparum, 1709 xxiv SUBJECT INDEX MOL. CELL. BIOL.

respiratory syncytial virus glycoprotein c-fos expression, 5080 platelet-derived growth factor, 3345 G, 1709 homodimer expression polyomavirus middle-T antigen, 1736 transport to cell surface, 1709 human fibroblasts, 2753 protein-tyrosine kinase activity, 3345 per clock protein rat-I cells, 2753 regulation by autophosphorylation site in D. melanogaster, 5378 human, 571, 2089, 3476 overexpressed protein, 4541 PFY c-myc expression, 5080 Ser-17 substitution, 1826 Saccharomyces cerevisiae, 5108 NIH 3T3 cells expressing EJ-ras, 5052 v-src/c-src chimeras, 704 Pheromone arrest p21 v-ras, 5080 transformation, 704 DAFI, 4675 pp60c-src pp6Ov-src S. cerevisiae, 4675 phosphorylation, 3345 chicken embryo lens cells, 1414 Phorbol ester protein-tyrosine kinase activity, 3345 myristylation, 2435 thyroid cell proliferation receptor, 3476 myristylation in a cell-free system, 4295 protein phosphorylation, 2494 anti-peptide antibody, 36% reconstitution into liposomes, 18% Phorbol tetradecanoate acetate signal transduction, 5126 Prealbumin gene c-erbB-2 gene product, 1019 c-sis, 2089 mouse, 81 Phosphate permease v-sis protein, 1011 Pre-mRNA N. crassa, 1376 tyrosine kinase, 5126 HeLa cells, 2884 Phosphatidylglycerolphosphate synthase Platelet-derived growth factor 2 primary structure, 2884 expression 5' untranslated sequence, 284 ribonucleoprotein, 2884 inositol, 4773 translational inhibition, 284 S. cerevisiae, 3755 S. cerevisiae, 4773 Poliovirus spliceosome pathway, 3755 Phosphoenolpyruvate carboxykinase gene HeLa cells, 3175 Pre-mRNA processing cAMP elements, 3467 mRNA translation, 1103 human growth hormone, 2011 glucocorticoid response elements, 96 transcription inhibition, 3175 plants, 2042 promoter, 3467 Poly(A) Pre-mRNA splicing rat, 96 human c-myc RNA, 1697 downstream exon, 860 Phosphoglycerate kinase gene Poly(A) site downstream elements 3-globin intron, 4484 demethylation of specific sites, 4692 adenovirus E2, 1839 human, 860, 4484 human, 4692 cleavage activity, 1839 MuSVtsl 10 retrovirus, 1558 Phospholipid vesicles SV40, 1839 NRK cells, 1558 pp60v_src, 1896 Polyadenylation site selection Pre-pro-transforming growth factor beta Phosphorylation patterns, 4829 CHO cells, 4162 tyrosine 527 Polyadenylation-specific 25S ribonucleo- Pre-tRNA pp6Oc-src, 2465 protein complex, 2052 S. cerevisiae, 5140 Phosphotyrosine antibody screening of Polyadenylation-specific complexes Prion gene complex cDNA libraries adenovirus type 2, 226 mouse, 5528 mouse, 5541 Polycistronic pre-mRNAs scrapie incubation time, 5528 tyrosine kinase, 5541 T. brucei heat shock, 3837 Procyclic acidic repetitive protein gene phy Polylactosaminoglycans T. brucei, 4055 A. sativa, 4840 influenza B virus NB, 1186 Progesterone receptor-binding sites phytochrome, 4840 Polyomavirus chicken vitellogenin II gene, 5323 Physarum polycephalum BK enhancer, 3448 Prolactin upstream factor I spindle DNA replication, 5000 rat, 5432 P-tubulin, 1275 enhancer core sequences, 1993 Promoter binding Phytochrome enhancer elements and subelements class III transcription factors, 3017 A. sativa, 4840 DNA replication, 5000 Promoter competition cab transcription, 4840 human, 3448 S. cerevisiae, 4608 phy transcription, 4840 middle T antigen Prostatic phosphotyrosyl phosphatase Pig S6 phosphorylation, 2309 epidermal growth factor receptor, 5477 class I major histocompatibility complex middle-T antigen human, 5477 gene, 695 pp60c-src carboxy terminus, 1736 Protamine-myc pim-l gene product middle-T-antigen gene haploid-specific transcription, 1748 human, 1498 human c-myc oncogene, 2261 mouse, 1748 tyrosine kinase activity, 1498 rat, 2261 Protamine-T-antigen fusion genes Plants mouse, 2309 haploid-specific transcription, 1748 pre-mRNA processing, 2042 Polytene chromosomes mouse, 1748 Plasmid pSRI D. melanogaster, 1877 Protein antigen gene conversion, 955 p75, 1877 actin microfilaments, 564 S. cerevisiae, 955 Postmeiotic segregation chicken, 564 Z. rouxii, 955 S. cerevisiae, 1253 integrin ,-chain, 564 Plasmodium falciparum Potassium transport Protein binding merozoite surface antigens, 2664 S. cerevisiae, 2848 loop I of U1 small nuclear RNA, 4787 peptide sequence transport to cell sur- TRKJ, 2848 face, 1709 ppS6'c/ Protein kinase C Plastin neoplastic transformation, 540 human ets-2 protein stabilization, 4700 human, 4659 pp60c-src mouse, 5448 Platelet tyrosine-specific protein phosphor- carboxy terminus, 1736 T-cell antigen receptor ylation chicken embryo fibroblasts, 1826 transmembrane signalling, 5448 human, 3603 dog kidney cells, 632 Protein phosphorylation thrombin, 3603 Madin-Darby canine kidney cells, 632 epidermal growth factor, 2494 Platelet-derived growth factor mouse brain, 502 phorbol ester, 2494 A-chain cDNA and gene, 571 NIH 3T3 cells, 704 thyroid cell proliferation, 2494 c-fos, 5052 phosphorylation on tyrosine 527, 2465 thyrotropin, 2494 VOL . 8, 1988 SUBJECT INDEX xxv

Protein sorting ras protein, mutant polyomavirus middle-T-antigen gene, S. cerevisiae vpt mutants, 4936 mouse, 3235 2261 Protein synthesis initiation factor eIF-2 RAS proteins prolactin upstream factor I, 5432 human, 993 adenylate cyclase, 52 ras, 2668 mutant form lacking site of phosphoryla- GTP hydrolysis, 2472 c-H-rasl expression, 1460 tion by eIF-2 kinases, 993 guanine nucleotide exchange, 2472 retinoic acid, 1845 Protein tyrosinase kinase S. cerevisiae, 52 sequence-specific DNA-protein com- neoplastic transformation, 540 transforming potential, 2472 plexes, 1947 Proteinase A propeptide RAS-responsive adenylyl cyclase complex somatostatin gene, 1947 S. cerevisiae, 2105 S. cerevisiae, 2159 src, 138 vacuolar hydrolase, 2105 Rat SV40 oncoprotein, 5495 Protein-tyrosine kinase activity adenovirus EIA oncogene, 1756 SV40-immortalized hepatocyte lines platelet-derived growth factor, 3345 adenovirus serotype 5 Ela protein, 3882 tumorigenicity, 4492 pp60c-src, 3345 adenovirus type 2 t(6;7) chromosomal translocation, 441 PsA Ela gene, 2984 transformation, 2668 D. discoideum, 3458 adenovirus type 5 EIA 12S protein, 3191 transformation assay, 1845 PUn2 a,-acid glycoprotein gene, 42 transforming growth factor alpha, 2999 proline-specific induction, 4634 beta nerve growth factor, 452 transforming growth factor beta, 2479 S. cerevisiae, 4634 carboxykinase gene, 96 transin gene expression, 2479 upstream activation site, 4634 cDNA, 4243 a-tropomyosin gene splicing, 679 PYR3 COS-1 cells, 35 vasopressin mRNA poly(A) tract length U. maydis, 5417 COUP transcription factor, 2070 modulation, 2267 cytochrome c promoter elements, 35 RBI gene Quail DNA synthesis, 1670 retinoblastoma tumors, 2082 proviral insertional activation of c-erbB, hypomethylation, 1443 Recombination 4868 elastase I enhancer, 893 carcinogen induced, 1% troponin I gene in mice, 5059 y-enteric actin cDNA, 5224 homology requirements, 5350 epidermal growth factor, 2479 mouse, 5350 RIBm epithelial cell immortalization by EIA mouse L cells, 196 B. mori, 114 retrovirus, 1036 S. cerevisiae RADI, 3619 non-long-terminal repeat retrotranspo- a,-fetoprotein gene, 1398 v-rel son, 114 c-fos protein, 1670 B-cell isolation, 5358 Rabbit c-fos transcriptional activation, 2787 chicken, 5358 DNA replication, 3272 Fos-related antigen, 2063 REOI DPf3 gene conserved sequences fra-1, 2063 S. cerevisiae COX5a and COXSb, 4537 protein binding, 2034 glucagon expression, 4877 Reovirus herpes simplex virus, 3272 glucocorticoid response elements outer capsid protein u3 intron-dependent and -independent gene carboxykinase gene, 96 dsRNA-binding site, 273 expression, 4395 glucocorticoid suppression of tumor cell zinc-binding site, 273 growth, 1449 Replication origins RAD1 glucocorticoids, 203 pea chloroplast DNA, 1216 recombination, 3619 glucose transport, 138 Replicon mapping, 1408 S. cerevisiae, 3619 growth, 1756 Respiratory syncytial virus glycoprotein G RAD6 protein growth factor induction, 3191 P. falciparum carboxyl-terminal polyacidic sequence, GRP78 transcription, 4579 peptide sequence transport to cell sur- 1179 hepatocyte-stimulating factor, 42 face, 1709 S. cerevisiae, 1179 HSV infection, 1443 ret B-raf human c-myc oncogene, 2261 human "finger"-containing gene, 1853 DNA rearrangement, 2651 human p92c-fes, 578 Reticuloendotheliosis virus mouse, 2651 hypomethylation of DNA synthesis after chicken Rainbow trout HSV infection, 1443 B-cell isolation, 5358 metallothionein B gene, 4469 immortalization of primary epithelial long terminal repeat RAP30/74 cells, 3191 DNA binding, 5232 RNA polymerase II initiation factor, insulin II gene, 2070 transcriptional elements, 5232 1602 P2 interferon, 42 Retinoblastoma tumors RAS interleukin-l, 42 human, 2082 adenovirus Ela, 2177 liver maturation, 203 RB1 gene, 2082 L-myc, 2668 malic enzyme gene promoter, 3542 Retinoic acid rat fibroblast transformation, 2668 metastatic potential, 2984 ERA-I c-H-RASI mRNA, 4243 homeobox domain, 3906 Rat-I 1460 B-myc, 3168 mouse, 3906 cells, c-myc, 441 rat embryo fibroblast transformation as- H-RAS L-myc, 2668 say, 1845 keratoacanthomas, 786 N-myc: ,-galactosidase fusion proteins, Retrotransposon Ty K-RAS 4529 functional organization, 1421 point mutations myoblasts temperature sensitive for dif- protease, 1421 clonal murine lymphomas, 2233 ferentiation, 2335 S. cerevisiae, 1421 RAS mutation myosin light-chain 2 gene Retrotransposon Ty3 CDC25 requirement for growth, 2980 expression in mice, 1006 homology to animal retroviruses, 5245 S. cerevisiae, 2980 nerve growth factor, 452 S. cerevisiae, 5245 N-RAS opsin expression in retina, 1570 Retrovirus point mutations platelet-derived growth factor homodi- cDNA gene formation, 2328 clonal murine lymphomas, 2233 mers, 2753 genetic tagging of tumor cells, 3143 xxvi SUBJECT INDEX MOL. CELL. BIOL.

hematopoietic stem cell proliferation, TFIID, 3175 chromosome maintenance, 2184 3864 Rous sarcoma virus chromosome rearrangements human myeloid leukemic blast stem cells chicken direction by his3 recombinational sub- new genetic material, 974 tyrosine protein kinase, 3035 strates, 4370 mouse, 3143 pp60v-src myristylation, 2435 CKAI, 4981 neo, 974 pp60v-src reconstituted into liposomes, clustered meiotic exchanges, 595 rat epithelial cell immortalization, 1036 18% cob gene, 2562 triple-promoter retroviral vectors RNA splicing and stability, 4858 constitutive binding factor, 5299 mammalian cell transformation, 1803 ROXI COX5a, 4537 Retrovirus SL3-3 ANBI and CYC7 regulation, 4651 COX5b, 4537 enhancer-binding proteins in mouse lym- S. cerevisiae, 4651 CYCI phocytes, 1625 RPA1O upstream activation sequence 2, 647 Ribonucleoprotein S. cerevisiae, 3997 CYC7 regulation, 4651 HeLa cells, 2884 temperature-sensitive mutations, 3997 cytochrome c gene activation sites, 2275 pre-mRNA primary structure, 2884 rRNA DAFI, 4675 Ribonucleoprotein complexes A. castellanii, 1940 DNA-binding factors, 210 L. enriettii, 2597 synthesis enzyme inactivation, 2647 trans splicing, 2597 p16, 3406 ESP], 5386 Ribonucleotide reductase cDNA transcription, 1940 FLP protein-promoted site-specific re- mouse, 2698 rRNA promoter combination Ribosomal DNA A. castellanii, 747 Holliday intermediates, 3784 enhancers RNA polymerase I, 747 reaction by-products, 3784 X. laevis, 4282 single base substitutions, 747 G protein S. cerevisiae, 4927 transcription initiation factor, 747 a subunit gene, 2484 Ribosomal protein S6 GAL3, 3439 mouse, 2309 S promoter GALll protein, 4991 polyomavirus middle T antigen, 2309 hepatitis B virus, 2449 GCN2 protein kinase, 2132 Ribosomal protein S14 Saccharomyces cerevisiae GCN3, 4808 D. melanogaster, 4314 2>m plasmid, 4949 GCN4, 2132 Ribosomal proteins ACE], 2745 GCN4 mRNA S. cerevisiae, 169 ACP2, 1282 translational control, 3827 Ribosome synthesis ADE8 mutations, 1253 upstream open reading frames, 5439 D. melanogaster, 91 S-adenosyl transferase, 5132 gene conversion, 2442 heat shock, 91 adenovirus transcriptional regulatory gene expression, 2572 RNA regions, 3717 glucose-induced cAMP signal in ras mu- 7SL component of signal recognition adenylate cyclase, 52 tants, 3051 particle, 1580 adenylate cyclase gene, 5555 GPAI, 3777 D. melanogaster Antennapedia gene, adenylyl cyclase, 2159 HAP2, 4537 4143 ADRI binding to upstream activating HAP3, 655 double stranded sequence of ADH2, 4552 heat shock, 5555 binding site in reovirus outer capsid ADRI transcription factor, 1868 heat shock factor binding, 5040 protein a3, 273 ADRI transcriptional activator, 2125 heme, 4537 polymerase III transcription factor B a-factor pheromone, 1309 heteroduplex DNA, 5292 growth-restricted cells, 1001 a-factor signal sequence mutations, 1915 HIS4 translation initiation, 2955 reovirus outer capsid protein a3, 273 a-specific gene control, 309 HIS4 translation initiator region, 2964 Rous sarcoma virus, 4858 aminotriazole resistance, 664 histone RNA, 945 S. pombe, 1580 ANBI regulation, 4651 HMG1-like protein, 1282 splicing, 4143 ARS, 2184 HO-induced chromosomal breaks, 3918 splicing and stability, 4858 ATRJ, 664 hsp58, 371 RNA8 autonomously replicating sequences, 210 hsp7O transcription mutants, 3423 S. cerevisiae, 1067 bent DNA, 2763 3-hydroxy-3-methylglutaryl coenzyme A RNAII protein branched-chain amino acid biosynthesis, reductase, 3797 S. cerevisiae spliceosome, 2379 2690 inositol, 4773 RNA duplex unwindase C. elegans repetitive DNA with ARS intron 5 mammalian cells, 770 and segregation function, 875 cob gene, 2562 RNA polymerase I calcium-sensitive growth, 3094 iso-l-cytochrome c gene, 1045 A. castellanii, 747 cAMP phosphodiesterase karyoskeletal protein-enriched fractions RNA polymerase II low Ki,m 505 thermal stabilization, 4573 carboxyl-terminal domain, 321, 330 cAMP signal in ras mutants, 3051 L2 ribosomal protein genes D. melanogaster, 321 carbon regulation, 3439 gene disruption, 4792 human, 3136 LEU3 activates multiple genes, 2690 mammalian, 321, 4028 CDC7, 293 Ml virus replication mouse, 330 CDC25, 2980 mak suppression by L-A dsRNA vari- preinitiation complex assembly Cdc28 protein kinase, 2976 ant, 938 nucleosomal template transcription, CDC33, 3556 MAL63, 1027 3114 cell cycle kinetics, 4675 MAL64-C, 1027 RAP30/74, 1602 cell-type-specific genes, 551 maltose fermentative enzymes, 1027 S. cerevisiae, 321 cellular protein inactivation, 2638 mating, 1309 transcription, 4028 centromere DNA mating defects, 822 transcription elongation factor S11, 3136 chromosome VI, 2523 mating factor signaling pathway, 3777 transcription factor chromosome III, 595 mating pheromone signaling, 2484 HeLa cells, 3175 chromosome VI mating type switching poliovirus, 3175 centromere DNA, 2523 physical monitoring, 2342 VOL . 8, 1988 SUBJECT INDEX xxvii

mating-factor signaling pathway, 5410 SUP4-o, 978 Sex-limited protein meiosis, 293 SUP53 tRNA gene transcript processing, mouse, 2350 membrane translocation, 1915 361 SGP2 metallothionein gene regulation, 2745 TCMI transcriptional activation, 4328 mating-factor signaling pathway, 5410 mitosis, 293 TDH3 S. cerevisiae, 5410 mRNA 3'-end formation, 1045 chromatin structure, 5513 Signal transduction mRNA cap-binding protein eIF-4E, 3556 telomere-associated sequences, 2257 platelet-derived growth factor receptor, mRNA structures, 1591 telomeres, 210, 5086 5126 mRNA-decapping enzyme, 2005 telomeric DNA processing, 4642 tyrosine kinase, 5126 MRP7, 3636 TMPI Silencers MRP13, 3647 periodic transcription, 4616 S. cerevisiae, 5086 multistress resistance, 5555 trans-acting factor, 2572 telomeres, 5086 PFY, 5108 transcription, 2184 upstream activating sequences, 5086 pheromone arrest, 4675 transcription-translation regulation, 2132 Simian virus 40 phosphatidylglycerolphosphate synthase translation, 1591 72-Base-pair repeat, 1509 expression, 4773 translation initiation by non-AUG co- camptothecin, 3026 plasmid pSRI, 955 dons, 4533 capture of nuclear sequence-specific postmeiotic segregation frequency, 1253 trifluoperazine resistance gene DNA-binding proteins, 982 potassium transport, 2848 calcium-sensitive growth, 3094 DNA breakage, 3026 pre-mRNA commitment in the spliceo- FOF1 ATP synthase, 3094 DNA replication, 1509 some pathway, 3755 TRKI, 2848 entry into polarized epithelial cells, 3391 pre-tRNA processing, 5140 ,B-tubulin large-T-antigen-transforming and origin- promoter competition, 4608 carboxy-terminal deletion, 2730 binding functions, 1380 promoters, 4217 Ty major late promoter, 2021 protein decay, 169 functional organization, 1421 monkey, 2428, 3026 protein similar to galactokinases, 3439 protease, 1421 mouse, 1380 protein sorting, 4936 transposition, 3571 mutagenesis in mitomycin C-treated proteinase A propeptide, 2105 Tyl, 1432 monkey cells, 3943 PUT2 upstream activation site, 4634 Tyl cell-type-specific responsive ele- oncoprotein RADI ment, 5299 nuclear targeting, 5495 recombination, 3619 Tyl sequence responsive to STE, 2545 origin of DNA replication RAD6 protein, 1179 Ty3, 5245 monkey cells, 903 ras mutants, 3051 Ty elements poly(A) site downstream elements RAS mutation, 2980 meiotic recombination, 2942 cleavage activity, 1839 RAS proteins, 52 Ty inserted into adenylate cyclase gene, polyadenylation site selection, 4829 RAS-responsive adenylyl cyclase com- 5555 replication, 515 plex, 2159 Ty-adjacent gene expression, 4009 replication of UV-damaged DNA in recombination hotspots, 1253 Ty-mediated enhancement of gene mammalian cells, 2428 REOI, 4537 expression, 2572 small tumor antigen replication enhancer, 2763 UASGal elements, 3439 tumorigenesis in transgenic mice, 3382 ribosomal DNA, 4927 UBI4, 1132 small-t antigen pre-mRNA splicing, 3582 ribosomal protein accumulation, 169 upstream activating sequences, 210, 5086 SRa promoter, 466 RNA8, 1067 upstream open reading frames, 5439 synthetic peptide nuclear transport sig- RNA1 protein, 2379 vacuolar hydrolase, 2105 nals, 2722 RNA polymerase I subunit gene, 3997 vacuolar hydrolase mutants, 4936 T antigen RNA polymerase II Z. rouxii plasmid pSRI, 955 DNA binding, 1648 carboxyl-terminal domain, 321 SAM2 trans activation of type I interferon ROXI, 4651 S-adenosyl transferase, 5132 promoters, 3397 RPA190 S. cerevisiae, 5132 topoisomerase, 515 temperature-sensitive mutations, 3997 Satellite DNA Simian virus 40-immortalized hepatocyte SAM2, 5132 tk gene expression cell lines SEC18 gene product, 4098 mouse, 1336 tumorigenicity, 4492 secretion machinery, 4098 Schistosoma mansoni c-sis SGP2, 5410 developmentally regulated transcripts, human, 2089 silencers, 210, 5086 4745 overexpression, 2089 size control, 4675 eggshell (chorion) protein gene family, platelet-derived growth factor 2, 2089 small nuclear RNAs, 3282 3008 v-sis protein SNR, 3282 Schizosaccharomyces pombe nonessential disulfide bonds, 1011 snRNAs, 3150 centromeric DNA, 754 platelet-derived growth factor B chain, spindle pole duplication, 5386 RNA homologous to the 7SL component 1011 spliceosome, 2379 of signal recognition particle, 1580 c-sis/platelet-derived growth factor 2 spore wall maturation, 912 translational inhibitor, 284 sporulation, 5166 U2 small nuclear RNA, 5575 Skeletal actin promoter SPSIOO, 912 Scrapie chicken, 1800 SPT3, 822 incubation time, 5528 DNA-binding site, 1800 SRA5, 505 mouse, 5528 Skeletal a-actin gene STE7, 551 prion gene complex, 5528 promoter, 4587 STEII, 551 Sea urchin Skeletal myosin alkali light-chain gene STE12, 551 histone gene regulation chicken, 2581 STE genes, 3777 X. laevis oocytes, 1236 upstream regulatory region, 2581 STE-responsive element, 2545 U7 small nuclear RNA, 1076 Small nuclear RNA STPI, 5140 SEC18 loop I SUP4(G37), 5140 S. cerevisiae, 4098 protein binding, 4787 xxviii SUBJECT INDEX MOL. CELL. BIOL.

mouse, 1518 STE genes Telomeric DNA processing U7, 1518 GPAI, 3777 S. cerevisiae, 4642 Small nuclear RNAs mating factor signaling pathway, 3777 Testicular a tubulin S. cerevisiae, 3150 S. cerevisiae, 3777 divergent form, 996 S. cerevisiae SNR, 3282 STPl mouse, 996 Small-cell lung cancer S. cerevisiae, 5140 12-0-Tetradecanoylphorbol- 13-acetate myc gene family Strongylocentrotus purpuratus mouse, 2247 transcriptional regulation, 3373 late histone subtype Hi-p gene, 1842 myeloid colony-stimulating factor Small-t antigen pre-mRNA Sulfur regulatory circuit expression, 3432 splicing, 3582 cys-14+, 1504 VL30, 2247 SV40, 3582 N. crassa, 1504 Tetrahymena malaccensis a-Smooth muscle actin gene core promoter SUP4(G37) mitochondrial DNA telomeric repeats chicken, 241 S. cerevisiae, 5140 multimodal distribution, 4450 SNR SUP4-o Tetrahymena thermophila S. cerevisiae, 3282 S. cerevisiae, 978 cell cycle, 2681 Somatostatin gene spontaneous mutations, 978 cilia regeneration, 2681 rat, 1947 SUP53 tRNA gene transcripts cytoplasmic exchange, 2681 sequence-specific DNA-protein com- S. cerevisiae, 361 DNA deletion junctions, 3947 plexes, 1947 Surface protein hsp58, 371 Soybean mRNA stability, 427 hvl, 4780 Gmhsp26-A, 1113 T. thermophila, 427 mRNA, 427, 4780 SPI Surface protein gene family nuclear development, 2681 adenovirus major late promoter tran- T. thermophila, 5043 surface protein, 427 scription factor, 2628 Surfeit locus surface protein gene family CAAT-binding factor, 2628 clustered genes, 3898 rearrangements during development, y-fibrinogen promoter, 2628 mouse, 3898 5043 a-Spectrin genes Synthetic peptide nuclear transport signals, transformation with hypermethylated homology among diverse species, I 2722 rRNA genes, 1664 Spindle pole duplication TFIID, 4028 ESP], 5386 t(6;7) chromosomal translocation HeLa cells, 3175 S. cerevisiae, 5386 c-myc breakpoint clustering, 441 poliovirus, 3175 Spleen necrosis virus rat immunocytomas, 441 RNA polymerase II transcription factor, cDNA gene formation, 2328 T antigen 3175 Splice sites DNA binding, 1648 Thermoresistance K-immunoglobulin precursor mRNA, SV40, 1648 hsp68, 5486 2610 Tagging of tumor cells mouse plasmacytomas, 5486 Spliceosome mouse, 3143 Thrombin RNAII protein, 2379 retrovirus vectors, 3143 human platelets, 3603 S. cerevisiae, 2379 TATA box-dependent protein-DNA inter- tyrosine-specific protein phosphoryla- Spliceosome gels, 814 actions tion, 3603 Spores D. melanogaster Thy-i S. cerevisiae, 912 heat shock promoter, 3204 mouse, 3847 SPS100, 912 histone gene promoter, 3204 Thy-I glycoprotein wall maturation, 912 Tcl glycolipid anchors, 674 Sporulation C. elegans, 737 Thymidine kinase S. cerevisiae, 5166 T-cell activation human, 1551 SPS100 mouse, 4353 Thymidine kinase gene S. cerevisiae, 912 pS6Ick, 4353 insertional activation of promoterless spore wall maturation, 912 T-cell activation signals gene, 3298 SPT3 mouse granulocyte-macrophage colony- mouse, 3298 mating defects, 822 stimulating factor gene, 5581 Thyroid cell proliferation S. cerevisiae, 822 T-cell antigen receptor epidermal growth factor, 2494 SRAS mouse, 5448 phorbol ester, 2494 cAMP phosphodiesterase transmembrane signalling protein phosphorylation, 2494 low Km, 505 protein kinase C, 5448 thyrotropin, 2494 S. cerevisiae, 505 T-cell receptor alpha-chain genes Thyrotropin SRa promoter, 466 mouse, 5459 thyroid cell proliferation src TCMI protein phosphorylation, 2494 chicken, 138 S. cerevisiae, 4328 TIMP gene glucose transport, 138 transcriptional activation, 4328 mouse, 3227 rat, 138 TDH3 transcription regulatory elements in in- v-src chromatin structure, 5513 tron, 3227 lymphoid specificity, 234 S. cerevisiae, 5513 TIS gene expression tyrosine kinase region, 234 Telomere-associated sequences mouse, 4570 v-src/c-src chimeras S. cerevisiae, 2257 tk NIH 3T3 cells, 704 Telomerelike sequences mouse, 5280 pp6Ocsrc transformation, 704 P. tetraurelia, 4765 T-lymphocyte activation sry h-i Telomeres 4F2HC gene, 3809, 3820 D. melanogaster, 4459 P. tetraurelia, 251 human, 3809, 3820 STE S. cerevisiae, 210, 5086 TMPI cell-type-specific genes, 551 silencers, 5086 periodic transcription, 4616 S. cerevisiae, 551 upstream activating sequences, 5086 S. cerevisiae, 4616 VOL. 8, 1988 SUBJECT INDEX xxix

Topoisomerase dation, 802 S. cerevisiae, 2730 SV40 replication, 515 Translocation Tumor cell tagging Topoisomerase II c-myc regulation, 124 mouse, 3143 chicken, 3661 trans-splicing reaction retrovirus, 3143 DNase hypersensitivity, 3661 group II intron domain 5, 2361 Tumor necrosis factor trans splicing Transthyretin gene bovine endothelial cells, 5588 L. enriettii, 2597 mouse, 81 cycloheximide, 3432 ribonucleoprotein complexes, 2597 Trifluoperazine resistance gene human endothelial cells, 5588 T. equiperdum, 1352 calcium-sensitive growth, 3094 human myogenesis, 2295 trans-acting factor FOF1 ATP synthase, 3094 myeloid colony-stimulating factor a-actin genes, 4120 S. cerevisiae, 3094 expression, 3432 neurotransmitter gene transcription regu- Triosephosphate isomerase 12-O-tetradecanoylphorbol 13-acetate, lation, 4225 human, 802 3432 trans-activating element mRNA degradation, 802 thrombomodule gene transcription, 5588 HIV-1 and HIV-2, 2555 TRKI Tumor promoter phorbol ester Transcription potassium transport, 2848 epidermal growth factor receptor, 2302 adenovirus Ella late promoter, 1906 S. cerevisiae, 2848 mitogenic blocks, 2302 Transcription elongation factor SII tRNATrPG amber suppressors Ty RNA polymerase II, 3136 C. elegans, 3627 adenylate cyclase gene, 5555 Transcription factor tRNAAla genes adjacent gene expression, 4009 human KB cell mitochondria, 3496 Bombyx genome, 5504 functional organization, 1421 Transcription factor TFIIIA tRNAAsn gene gene expression, 2572 X. Iaevis, 1684 D. melanogaster, 4441 protease, 1421 Transcription factors transcription, 4441 S. cerevisiae, 1421, 2572, 3571, 4009, adenovirus E4, 1290 tRNATYr 5555 human, 3017 anticodon, 3332 trans-acting factor, 2572 promoter binding, 3018 D. melanogaster, 3322, 3332 transposition, 3571 Transcription initiation genes, 3322 Tyl human, 5549 Tropomyosin II gene constitutive binding factor, 5299 transforming growth factor alpha pro- D. melanogaster, 3591 S. cerevisiae, 1432, 2545, 5299 moter, 5549 a-Tropomyosin STE-responsive element, 2545 Transcription initiation factor gene Ty3 A. castellanii, 747 alternative splicing, 679 homology to animal retroviruses, 5245 Transcription termination rat, 679 S. cerevisiae, 5245 chicken, 5369 Tropomyosin isoform Ty elements pH-globin gene, 5369 Lewis lung carcinoma cells, 3934 meiotic recombination, 2942 c-myc gene, 4389 Tropomyosin isoform 3 S. cerevisiae, 2942 Transformation human fibroblasts, 160 Type 1 transforming growth factor a pre- assay, 1845 Troponin I gene cursor gene product that forms an hsc7O-p53 mouse, 5072 CHO cells, 2229 complex, 531 quail, 5072 glycosylation, 2229 mink mutant cells, 2419 Troponin complex gene expression phosphorylation, 2229 p53, 531 myogenesis, 4134 Tyrosine kinase pp56Ick, 540 quail, 4134 colony-stimulating factor 1, 1795 rat, 1845 Trypanosoma brucei erbB-2, 5570 retinoic acid, 1845 actin gene, 2166 mouse, 5541, 5570 Transformation-defective mouse cell vari- cytochrome c expression, 4625 mouse macrophage cell line, 1795 ant, 4190 heat shock, 3837 phosphotyrosine antibody screening of Transforming growth factor a 7-methylguanosine, 494 cDNA libraries, 5541 chicken, 1970 miniexon-derived RNA cap, 494 platelet-derived growth factor receptor, epidermal growth factor, 1970 mitochondrial transcripts, 1259 5126 human, 5549 mRNA cap, 494 signal transduction, 5126 mouse, 1970 polycistronic pre-mRNAs, 3837 Tyrosine kinase gene mouse fetus, 3415 procyclic acidic repetitive protein gene, eph, 3770 mutation, 1247 4055 Tyrosine kinase region structure-function analysis, 2999 uridine addition, 1259 v-abl, 234 transcription initiation, 5549 variant cell surface glycoprotein gene lymphoid specificity, 234 Transforming growth factor 1 1.8, 854 v-src, 234 fibronectin binding, 4234 variant-specific antigen gene, 2367 Tyrosine phosphorylation human, 4234 Trypanosoma equiperdum mouse fetus, 3415 trans splicing, 1352 v-fms transformation, 176 mouse keratinocytes, 3088 TTFI mouse proteins, 2214 rat, 2479 mouse ribosomal DNA transcription, p 185-neu, 3969 transin gene expression, 2479 3891 Tyrosine protein kinase Transin gene expression Tubulin mRNA chicken, 3035 epidermal growth factor, 2479 L. pictus embryo, 3518 Tyrosine-specific protein phosphorylation rat, 2479 protein synthesis, 3518 human platelets, 3603 transforming growth factor beta, 2479 1-Tubulins thrombin, 3603 Translation carboxy-terminal deletion, 2730 mRNA structures, 1591 mRNA, 1224 U 1 small nuclear ribonucleoprotein parti- S. cerevisiae, 1591 nucleotides specifying autoregulation, cles Translation termination 1224 gel electrophoretic isolation of splicing triosephosphate isomerase mRNA degra- P. polycephalum spindle, 1275 complexes containing, 814 xxx SUBJECT INDEX MOL. CELL. BIOL.

U2 small nuclear RNA S. cerevisiae, 2105 X-CGD gene adenovirus type 12 infection, 1863 S. cerei'isiae mutants, 4936 expression during HL-60 differentiation, fission yeasts and mammals, 5575 van 2804 fragile site, 1863 N. crassa, 1376 Xenopus laevis human, 1863 nluc-l, 1376 SS RNA genes S. pombe, 5575 Variant cell surface glycoprotein gene 1.8 expression, 4257 U4 small nuclear RNA, 5566 T. brucei, 854 transcriptional efficiency in an oocyte U7 small nuclear RNA Variant-specific antigen gene S1S0 extract, 5056 mouse, 1518 T. brucei, 2367 B 1-Alu expression sea urchin, 1076 VARNAI gene pathway, 4433 UASGal elements adenovirus type 2, 1147 cis effects of c-myc mRNA 5' region, S. cerevisiae, 3439 Vasopressin mRNA poly(A) tract 2875 UBI4 length modulation, 2267 DNA replication, 1301 S. cerevisiae, 1132 rat, 2267 ,B-globin gene activation, 1301 stress regulation, 1132 v-erbA histone gene promoters, 3676 Ubiquitin genes avian erythroblastosis virus, 4510 histone genes, 1236 D. melanogaster, 4727 functional domains, 4510 hsp58, 371 Upstream activating sequences Vesicular stomatitis virus human nerve growth factor receptors, S. cerevisiae, 210, 5086 glycoprotein transport 2242 silencers, 5086 altered cytoplasmic domains, 2869 mitochondrial DNA telomeres, 5086 Viral integration site transcription, 2917 Upstream activation sequence 2 AKXD murine myeloid tumor, 301 mitochondrial RNA polymerase, 2910 CYCI, 647 Evi-1, 301 ribosomal DNA enhancers, 4282 S. cerevisiae, 647 Vitellogenin II gene sea urchin histone 1236 Upstream activation site chicken, 5323 genes, S. cerevisiae PUn2, 4634 estrogen receptor-binding sites, 5323 transcription factor TFIIIA, 1684 Upstream open reading frames progesteron receptor-binding sites, 5323 S. cerevisiae GCN4 mRNA, 5439 Vitellogenin upstream region Yarrowia lipolytica Upstream promoter sequence chicken, 4557 alkaline extracellular protease Ad2, 105 nuclear factor binding, 4557 precursors and secretion, 4904 binding factors, 105 VL30 element YPI gene expression DNA affinity labeling, 105 epidermal growth factor, 2247 D. melanogaster, 4756 Urechis caupo mouse, 2247 core histone gene tandem repeat, 4425 protein kinase C activator, 2247 Zea mays Uridine addition transcriptional regulation, 2247 hsp58, 371 T. brucei mitochondrial transcripts, 1259 VL30 retro-element zeste Ustilago maydis mouse, 2989 D. melanogaster, 615 autonomously replicating sequence, 3703 nucleotide sequence, 2989 DNA binding, 615 PYR3, 5417 Zinc fingers UVB radiation Wheat-germ extracts mouse gene family, 1319 African green monkey kidney cells, 5425 cis effects of c-myc mRNA 5' region, Zinc-binding site 2875 reovirus outer capsid protein c3, 273 Vacuolar hydrolase Wolffish (A. lupus) Zygosaccharomyces rouxii proteinase A propeptide, 2105 antifreeze protein genes, 3670 plasmid pSRl, 955