Welcoming 62 New EMBO Members Marek Basler & Melina Schuh
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Annual Report Fy 2018 Human Frontier Science Program Organization
APRIL 2017 APRIL 2018 — MARCH 2019 ANNUAL REPORT FY 2018 HUMAN FRONTIER SCIENCE PROGRAM ORGANIZATION The Human Frontier Science Program Organization (HFSPO) is unique, supporting international collaboration to undertake innovative, risky, basic research at the frontier of the life sciences. Special emphasis is given to the support and training of independent young investigators, beginning at the postdoctoral level. The Program is implemented by an international organisation, supported financially by Australia, Canada, France, Germany, India, Italy, Japan, the Republic of Korea, New Zealand, Norway, Singapore, Switzerland, the United Kingdom of Great Britain and Nothern Ireland, the United States of America, and the European Commission. Since 1990, over 7000 researchers from more than 70 countries have been supported. Of these, 28 HFSP awardees have gone on to receive the Nobel Prize. 2 The following documents are available on the HFSP website www.hfsp.org: Joint Communiqués (Tokyo 1992, Washington 1997, Berlin 2002, Bern 2004, Ottawa 2007, Canberra 2010, Brussels 2013, London 2016): https://www.hfsp.org/about/governance/membership Statutes of the International Human Frontier Science Program Organization: https://www.hfsp.org/about/governance/hfspo-statutes Guidelines for the participation of new members in HFSPO: https://www.hfsp.org/about/governance/membership General reviews of the HFSP (1996, 2001, 2006-2007, 2010, 2018): https://www.hfsp.org/about/strategy/reviews Updated and previous lists of awards, including titles and abstracts: -
Reviewers [PDF]
The Journal of Neuroscience, January 2013, 33(1) Acknowledgement For Reviewers 2012 The Editors depend heavily on outside reviewers in forming opinions about papers submitted to the Journal and would like to formally thank the following individuals for their help during the past year. Kjersti Aagaard Frederic Ambroggi Craig Atencio Izhar Bar-Gad Esther Aarts Céline Amiez Coleen Atkins Jose Bargas Michelle Aarts Bagrat Amirikian Lauren Atlas Steven Barger Lawrence Abbott Nurith Amitai David Attwell Cornelia Bargmann Brandon Abbs Yael Amitai Etienne Audinat Michael Barish Keiko Abe Martine Ammasari-Teule Anthony Auger Philip Barker Nobuhito Abe Katrin Amunts Vanessa Auld Neal Barmack Ted Abel Costas Anastassiou Jesús Avila Gilad Barnea Ute Abraham Beau Ances Karen Avraham Carol Barnes Wickliffe Abraham Richard Andersen Gautam Awatramani Steven Barnes Andrey Abramov Søren Andersen Edward Awh Sue Barnett Hermann Ackermann Adam Anderson Cenk Ayata Michael Barnett-Cowan David Adams Anne Anderson Anthony Azevedo Kevin Barnham Nii Addy Clare Anderson Rony Azouz Scott Barnham Arash Afraz Lucy Anderson Hiroko Baba Colin J. Barnstable Ariel Agmon Matthew Anderson Luiz Baccalá Scott Barnum Adan Aguirre Susan Anderson Stephen Baccus Ralf Baron Geoffrey Aguirre Anuska Andjelkovic Stephen A. Back Pascal Barone Ehud Ahissar Rodrigo Andrade Lars Bäckman Maureen Barr Alaa Ahmed Ole Andreassen Aldo Badiani Luis Barros James Aimone Michael Andres David Badre Andreas Bartels Cheryl Aine Michael Andresen Wolfgang Baehr David Bartés-Fas Michael Aitken Stephen Andrews Mathias Bähr Alison Barth Elias Aizenman Thomas Andrillon Bahador Bahrami Markus Barth Katerina Akassoglou Victor Anggono Richard Baines Simon Barthelme Schahram Akbarian Fabrice Ango Jaideep Bains Edward Bartlett Colin Akerman María Cecilia Angulo Wyeth Bair Timothy Bartness Huda Akil Laurent Aniksztejn Victoria Bajo-Lorenzana Marisa Bartolomei Michael Akins Lucio Annunziato David Baker Marlene Bartos Emre Aksay Daniel Ansari Harriet Baker Jason Bartz Kaat Alaerts Mark S. -
Art + Design : News + Notes
ART + DESIGN : NEWS + NOTES COLLEGE OF ARCHITECTURE AND DESIGN – NEW JERSEY INSTITUTE OF TECHNOLOGY – NEWARK, NEW JERSEY – OCTOBER 2015 School of Art + Design Receives NASAD Accreditation Digital Design Student Animation Selected for Screening at MetroCAF 2015 in New York City The School of Art + Design successfully “Voice,” a completed its efforts in music and obtaining accreditation geometry- from the National inspired Association of Schools animation of Art and Design created in (NASAD). All three undergraduate four-year programs a second (Bachelor of Arts in Digital Design, Bachelor of Science year class in Industrial Design, and Bachelor of Arts in Interior by Digital Design student Nathalie Carrasco, was Design) in the School of Art + Design were accredited. selected and screened at MetroCAF 2015 on Friday, The Visiting Team described the efforts and impact of September 25. “MetroCAF is the annual New York City the School as “vibrant and commendable.” Metropolitan Area College Computer Animation Festival organized by the New York City ACM SIGGRAPH The accreditation was achieved through a collaborative Professional Chapter.” Eligibility extends to all students effort that required written reports, digital exhibit and attending a school within a 160-mile radius of Times physical exhibits of student work, and evidence of Square in New York City. Augustus Wendell, principal participation in regional and national arts communities and creative director of Kim.Wendell Design, LLC in and activities. Brooklyn, and Coordinator of the Digital Design program, was selected to serve on the MetroCAF jury. This achievement completes the suite of accreditations for the College of Architecture and Design in the last two years: CIDA (Interior Design); NAAB (Architecture); Recent Interior Design Graduate and Faculty NASAD (Art + Design). -
YEARBOOK Medicinal Chemistry in Europe
EFMC YEARBOOK Medicinal Chemistry in Europe EFMC-ISMC 2020 EFMC-YMCS 2020 EFMC-ASMC’19 Basel, Switzerland Basel, Switzerland EFMC-YMCS 2019 September 6-10, 2020 September 10-11, 2020 Special reports EFMC International Symposium on Medicinal Chemistry Basel, CH September 6-10, 2020 SESSIONS AND SESSION COORDINATORS EFMC AWARD LECTURES CHEMICAL BIOLOGY THERAPEUTIC AREAS – The Nauta Pharmacochemistry Award – The UCB-Ehrlich Award for Excellence in Medicinal CARBOHYDRATE RECOGNITION AND DRUG DESIGN ADDRESSING NEGLECTED AND EMERGING VIRAL Chemistry Alexander Titz (Helmholtz Institute for Pharmaceutical DISEASES WITH SMALL MOLECULES AFMC Session – The Prous Institute-Overton and Meyer Award for New Sciences, DE) Esin Aki-Yalçin (Ankara University, TR) Technologies in Drug Discovery CHEMICAL APPROACHES TO STEM CELL BREATHING LIFE INTO INHALED DRUG DISCOVERY: DIFFERENTIATION ICBS Session CHALLENGES AND BREAKTHROUGHS TO THE CLINIC EFMC PARTNER PRIZES Colin Pouton (Monash University, AU) ACSMEDI Session Nicole Goodwin(GSK, US) – The IUPAC-Richter Prize in Medicinal Chemistry CHEMICAL PROBES FOR TARGET DISCOVERY AND – The Klaus Grohe Prize VALIDATION CHEMICAL TOOLS AND DRUG DISCOVERY FOR Gyorgy Keseru (Hungarian Academy of Sciences, HU) NEUROINFLAMMATION EUCHEMS Session EFMC PRIZE LECTURES Sonsoles Martin-Santamaria (Biological Research Center, ES) MOLECULAR IMAGING TOOLS FOR CHEMICAL BIOLOGY Valle Palomo (CIB, ES) NEW STRATEGIES AND AGENTS FOR TARGETING – EFMC Prize for a Young Medicinal Chemist in Industry GRAMNEGATIVE PATHOGENS – EFMC Prize -
Crystallography News British Crystallographic Association
Crystallography News British Crystallographic Association Issue No. 119 December 2011 ISSN 1467-2790 22nd Congress of the IUCr in Madrid p6 BCA Meeting 2012 p12 National Facilities News p16 SAXS Course Leeds 2012 p24 ThreeThree Whishes Whishes Granted...Granted... TheThe new new D8 D8 VENTURE VENTURE withwith PHOTON PHOTON 100 100 zzHighzzHigh Performance Performance zzLowzz LowMaintenance Maintenance zzBrightestzzBrightest Microfocus Microfocus The D8The VENTURE D8 VENTURE is the is perfect the perfect answer answer to all to your all yourquestions questions in single in single crystal crystal X-ray X-ray structurestructure determination. determination. The D8The VENTURE D8 VENTURE features features excellent excellent sample sample access access and and visibility.visibility. The patentedThe patented doors doors either either can becan opened be opened in a sliding-door-modein a sliding-door-mode or as or swinging as swinging doors.doors. In addition In addition to single to single source source configurations configurations the theD8 VENTURED8 VENTURE accommodates accommodates dual dual wavelengthwavelength configurations. configurations. Based Based on the on principlesthe principles of DAVINCI.DESIGN of DAVINCI.DESIGN it is itengineered is engineered with withhigh highmodularity modularity from from best-in-class best-in-class components. components. www.bruker.comwww.bruker.com SC-XRDSC-XRD InnovationInnovation with with Integrity Integrity D8 VENTURED8 VENTURE 8.375 x 11.1258.375 xinch 11.125 2011.indd inch 2011.indd 1 1 07.06.201107.06.2011 14:23:19 14:23:19 EMPYREAN 100M 10M 1M The world of X-ray diffraction 0D Intensity [counts] 100K 10K 1K is no longer fl at 100 10 -6000 -4000 -2000 0 2000 4000 6000 Omega/2Theta [s] Intensity [counts] FWHM = 0.026 °2 1D 4000 θ Intensity [counts] 3000 Position 2Theta [deg.] (Copper Cu)) 2000 1000 0 20 30 40 50 60 70 80 90 100 110 120 130 140 Position 2Theta [deg.] (Copper (Cu)) 2D 3D The new Empyrean from PANalytical The only XRD platform is truly innovative, with cutting-edge technology in every aspect. -
Sculpture Trail Leaflet
1 nechemia azaz 1923–2008 natural growth, ripeness and fecundity. Of this welder. After the war he attended the Central created millions of years ago. He uses a piece Randall-Page wrote: ‘I have tried to make School of Arts and Crafts and became a full- pneumatic drill to make holes which join in Op Mobile No 10 1974 a sculptural equivalent of an emotional state time sculptor. the centre of the rocks and then carves shapes – the dark knotted centre, the consciousness around some of the holes, creating curious Painted aluminium tubing This architectural work is a focal point of of being alone’. protrusions. Sound is an element in these Purchased by the University Rootes Square, where its bright colour and works so if you gently hit your hand against curved forms stand in contrast to the angular Azaz was born in Berlin yet spent his childhood these, percussive sounds are made. Two of 5 avtarjeet dhanjal b 1940 sixties architecture of the student residences. in Palestine. After training as a stonemason the pieces incorporate an electronic device Austerely abstract, as underlined by its title in Bologna he studied sculpture in the which transmits natural sounds the artist has Grown in the Field 1976 3B Series I, it utilises industrial materials and Netherlands and Paris. recorded. Aluminium methods of production. The careful positioning This brightly coloured mobile reflects the Commissioned and presented to the University by of different shapes draws attention to the original colour scheme of the Arts Centre, Alcan Aluminium (UK) Ltd, 1977 internal negative spaces they define. -
YEARBOOK 2021 | 1 Editorial
EFMC Yearbook 2021 Medicinal Chemistry and Chemical Biology in Europe EFMC-ISMC International Symposium on Medicinal Chemistry Virtual Event Aug. 29-Sept. 2, 2021 SESSIONS AND SESSION NEXT GENERATION DRUGS FOR HEART CONFIRMED PLENARY LECTURES COORDINATORS FAILURE Alleyn Plowright, Wren Therapeutics, UK Phil Baran, The Scripps Research Institute, US CHEMICAL BIOLOGY Karin Briner, Novartis, US RECENT ADVANCES IN ANTICANCER DRUG Jean-Paul Clozel, Idorsia, CH CARBOHYDRATE RECOGNITION AND DRUG DISCOVERY Stefan Knapp, Goethe University Frankfurt, DE DESIGN Roberto di Santo, Sapienza University of Rome, IT Alexander Titz, Helmholtz Institute for Pharmaceutical Sciences, DE TARGETING FIBROTIC DISEASES WITH SMALL MOLECULES EFMC AWARD LECTURES CHEMICAL APPROACHES TO STEM CELL Boehringer Ingelheim, DE DIFFERENTIATION (ICBS Session) THE NAUTA PHARMACOCHEMISTRY AWARD Colin Pouton, Monash University, AU TISSUE AND CELL SPECIFIC DRUG DELIVERY FOR MEDICINAL CHEMISTRY AND CHEMICAL (EUFEPS Session) BIOLOGY CHEMICAL PROBES FOR TARGET DISCOVERY Sébastien Papot, University of Poitiers, FR Ad P. Ijzerman, Leiden University, NL AND VALIDATION Gyorgy Keseru, Hungarian Academy of Sciences, HU TECHNOLOGIES IN MEDICINAL CHEMISTRY MOLECULAR IMAGING TOOLS FOR CHEMICAL Malin Lemurell, AstraZeneca, SE BIOLOGY APPLICATION OF ARTIFICIAL INTELLIGENCE Valle Palomo, CIB, ES IN DRUG DISCOVERY PROJECTS Christopher Swain, Cambridge MedChem AWARD FOR NEW TECHNOLOGIES IN DRUG PHOTOCHEMISTRY IN DRUG DISCOVERY: Consulting, UK DISCOVERY PHOTOPHARMACOLOGY, PHOTOTOXICITY Gisbert Schneider, ETH Zürich, CH AND SYNTHESIS (ACSMEDI Session) BIOCATALYSIS & LATE STAGE Timothy Henderson, MSD, US & Amjad Ali, MSD, US FUNCTIONALISATION Radka Snajdrova, Novartis, CH EFMC PARTNER PRIZES SMALL MOLECULES TARGETING RNA FUNCTION AND PROCESSING Maria Duca, University of Côte d'Azur, FR Jean-Paul Renaud, Urania Therapeutics, FR John E. Macor, Sanofi, US TARGET DECONVOLUTION STRATEGIES IN THE KLAUS GROHE AWARD DRUG DISCOVERY EXPANDING CHEMICAL SPACE THROUGH Stephan A. -
3.1 Consolidated Financial Statements of FUCHS PETROLUB SE
ANNUAL REPORT 2018 Pacesetter FUCHS PETROLUB SE | ANNUAL REPORT 2018 “ Technological advances, new possibilities within the Brief profile Brief – digital world, autonomous driving, e-mobility – these are all challenges that we want Locations – to use as opportunities. Our aim is to create a more agile company based on our values – Group structure Group with communication free – of hierarchies and with an open feedback culture.” Stefan Fuchs, Chairman of the Executive Board FUCHS at a glance a at FUCHS 2018 in 18 seconds € 2,567 million 2,473 2017 2018 EBIT € 383 million Sales + 4 % 14.9 % of sales R & D expenses 5,446 employees € 52 million (+ 256 ) FUCHS at a glance FUCHS Group Amounts in € million Change 2018 2017 in % Sales revenues 1 2,567 2,473 3.8 Europe 1,546 1,515 2.0 Asia-Pacific, Africa 783 733 6.8 North and South America 409 393 4.1 Consolidation – 171 – 168 1.8 Earnings before interest and tax and before income from companies consolidated at equity 357 356 0.3 in % of sales revenues 13.9 14.4 Earnings before interest and tax (EBIT) 383 373 2.7 Earnings after tax 288 269 7.1 in % of sales revenues 11.2 10.9 Investments in long-term assets 121 105 15.2 in % of scheduled depreciation 2 209 198 Free cash flow before acquisitions 3 147 142 3.5 Shareholders' equity 1,456 1,307 11.4 in % of balance sheet total 77.0 74.6 Balance sheet total 1,891 1,751 8.0 Employees as at December 31 4 5,446 5,190 4.9 Earnings per share (in €) Ordinary share 2.06 1.93 6.7 Preference share 2.07 1.94 6.7 Proposed dividend / dividend (in €) per ordinary share 0.94 0.90 4.4 per preference share 0.95 0.91 4.4 1 By company location. -
Reviewers [PDF]
The Journal of Neuroscience, January 2015, 35(1) Acknowledgement For Reviewers 2014 The Editors depend heavily on outside reviewers in forming opinions about papers submitted to the Journal and would like to formally thank the following individuals for their help during the past year. Kjersti Aagaard Ce´line Amiez Craig Atencio Deanna Barch Esther Aarts Bagrat Amirikian Coleen M. Atkins Yves-Alain Barde Michelle Aarts Nurith Amitai Lauren Atlas Izhar Bar-Gad Lawrence Abbott Yael Amitai Bernard Attali Jose Bargas Brandon Abbs Martine Ammassari-Teule David Attwell Steven Barger Keiko Abe Katrin M. C. Amunts Etienne Audinat Cornelia I. Bargmann Nobuhito Abe Costas A. Anastassiou Anthony P. Auger Michael E. Barish Ted Abel Beau Ances Vanessa Jane Auld Philip A. Barker Hermann Aberle Julie K. Andersen Jesu´s Avila Neal H. Barmack Ute Abraham Richard A. Andersen Karen B. Avraham Gilad Barnea Wickliffe C. Abraham Søren K. Andersen Edward Awh Carol A. Barnes Andrey Y. Abramov Adam Keith Anderson Nikolai Axmacher Gareth R. Barnes Thomas W. Abrams Anne E. Anderson Cenk Ayata Steven Barnes Hermann Ackermann Clare Anderson Anthony W. Azevedo Susan Carol Barnett David J. Adams Lucy A. Anderson Rony Azouz Michael Barnett-Cowan Nii Addy Matthew Peter Anderson Peter W. Baas Kevin Barnham Arash Afraz Susan Anderson Hiroko Baba Scott Barnham Ariel Agmon Anuska Andjelkovic Luiz Baccala´ Colin J. Barnstable Adan Aguirre Rodrigo Andrade Stephen Alexander Baccus Scott Barnum Geoffrey Karl Aguirre Ole A. Andreassen Stephen A. Back Ralf Baron Ehud Ahissar Michael Andres Lars Bäckman Pascal Barone Alaa A. Ahmed Michael C. Andresen Aldo Badiani Anne Baron-Van Evercooren Andrew H. -
Growing Together More Closely We Are Keen to Make Their Processes More Efficient
Growing together ANNUAL REPORT ANNUAL REPORT 2013 REPORT ANNUAL | LUBRICANTS. TECHNOLOGY. PEOPLE. FUCHS PETROLUB SE FUCHS PETROLUB is a global Group based in Germany, which produces and distributes lubricants and related specialties around the world. The Group, which was founded in 1931, with its headquarters in Mannheim, ranks num- ber one among the world’s independent lubricant providers. The Group currently employs a workforce of 3,888 in 50 operating companies in Europe and overseas. The most important regions for FUCHS in terms of sales revenues are Western Europe, Asia and North America. For 83 years, we have been concentrating all of our efforts and ideas on the development of innovative lubricants. We provide special lubricant solutions in market niches and offer our customers support in the world‘s key growth countries. Our local presence, coupled with the expertise and special understanding of values displayed by our employees, enables us to cater to individual customer requirements with tailor-made products. In this endeavor, we strive to utilize the strength of our global network and continue to grow as group. This is how we generate sustainable added value for our customers and all other stakeholders. FUCHS at a glance FUCHS PETROLUB GROUP Change Amounts in € million 2013 2012 in % Sales revenues 1 1,831.6 1,819.1 0.7 Europe 1,104.2 1,080.7 2.2 Asia-Pacifi c, Africa 497.9 486.8 2.3 North and South America 307.3 320.3 – 4.1 Consolidation – 77.8 – 68.7 13.2 Earnings before interest, tax and income from companies consolidated -
General Kofi A. Annan the United Nations United Nations Plaza
MASSACHUSETTS INSTITUTE OF TECHNOLOGY DEPARTMENT OF PHYSICS CAMBRIDGE, MASSACHUSETTS O2 1 39 October 10, 1997 HENRY W. KENDALL ROOM 2.4-51 4 (617) 253-7584 JULIUS A. STRATTON PROFESSOR OF PHYSICS Secretary- General Kofi A. Annan The United Nations United Nations Plaza . ..\ U New York City NY Dear Mr. Secretary-General: I have received your letter of October 1 , which you sent to me and my fellow Nobel laureates, inquiring whetHeTrwould, from time to time, provide advice and ideas so as to aid your organization in becoming more effective and responsive in its global tasks. I am grateful to be asked to support you and the United Nations for the contributions you can make to resolving the problems that now face the world are great ones. I would be pleased to help in whatever ways that I can. ~~ I have been involved in many of the issues that you deal with for many years, both as Chairman of the Union of Concerne., Scientists and, more recently, as an advisor to the World Bank. On several occasions I have participated in or initiated activities that brought together numbers of Nobel laureates to lend their voices in support of important international changes. -* . I include several examples of such activities: copies of documents, stemming from the . r work, that set out our views. I initiated the World Bank and the Union of Concerned Scientists' examples but responded to President Clinton's Round Table initiative. Again, my appreciation for your request;' I look forward to opportunities to contribute usefully. Sincerely yours ; Henry; W. -
Bioorganic & Medicinal Chemistry, Volume 11, Dec, 2003
MMCC Results Volume 15 No. 2 1 June 2006 Vol. 15, No. 2 1 June 2006 Coverage period: 1 April 2006 through 31 May 2006 Editorial and News About 105 papers from 20 journals are cited. As mentioned last month, the majority of the journal 1. APPLICATIONS ( 78 ) . page 2 reviews are now covered in the main section of the 1.1 Small Molecules – 40 reviews. General & Model systems-1 QSAR — 19 Water and Solvation – 2 Host-guest systems-4 I would call your attention on few highlighted Med Chem & Drug Design – 10 Carbon Nanoparticles – 3 articles, particularly in the Methodology section related to Liquid crystals-1 potentials and parameters. 1.2 Biopolymers – 34 R.Nageswar, Editor Bioinformatics – 3 Protein Dynamics – 5 Protein Folding - 1 Ligand Binding – 7 Protein Structure Prediction – 2 Protein-Protein Inter. – 2 Comp and Homol Modeling – 6 Membrane Proteins — 1 Protein Folding – 1 Free energy- 4 Protein Engg. & Design -2 1.3 Polymers – 1.4 Surfaces, Catalysts, and Materials Subjects — 5 2. METHODOLOGY (32) . page 19 QSAR - 4 Homology modeling – 1 Conformational Search & Anal -2 Mol.Graphics-2 Potentials and Parameters - 4 Ligand Docking — 4 Molecular Dynamics – 3 Surface volme - 1 QM/MM - 9 Protein structure prediction-2 3. JOURNAL REVIEWS (38) . page 26 J. Comp. Chem. 27 (8), 1 June 2006 J. Comp. Chem. 27 (9), 15 July 2006 J. Comp. Chem. 27 (10), 30 July 2006 Current Opinion in Structural Biology 16 (2) April 2006 4. ADDRESSES OF PRINCIPLE AUTHORS page 31 5. COPYRIGHT, DISCLAIMER AND PUBLISHER INFORMATION Page 1 1 June 2006 MMCC Results Volume 15 No.