Anti-MED6 (Full Length) Polyclonal Antibody (DPABH-09976) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-MED6 (full length) polyclonal antibody (DPABH-09976) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Immunogen Recombinant full length protein corresponding to Human MED6 aa 1-246.Sequence: MAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVV KMQRLTLEHLNQMVGIEYILLHAQEPILFIIRKQQRQSPAQVIPLADYYI IAGVIYQAPDLGSVINSRVLTAVHGIQSAFDEAMSYCRYHPSKGYWWHFK DHEEQDKVRPKAKRKEEPSSIFQ

Isotype IgG

Source/Host Mouse

Species Reactivity Human

Purification Protein A purified

Conjugate Unconjugated

Applications WB

Format Liquid

Size 50 μg

Buffer pH: 7.20; Constituent: 100% PBS

Preservative None

Storage Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Gene Name MED6 mediator complex subunit 6 [ Homo sapiens ]

Official Symbol MED6

Synonyms MED6; mediator complex subunit 6; mediator of RNA polymerase II transcription, subunit 6 homolog (S. cerevisiae); mediator of RNA polymerase II transcription subunit 6; NY REN 28; ARC33; hMed6; renal carcinoma antigen NY-REN-28; activator-recruited cofactor 33 kDa component; mediator of RNA polymerase II transcription, subunit 6 homolog; NY-REN-28;

Entrez Gene ID 10001

Protein Refseq NP_005457

UniProt ID O75586

Chromosome Location 14q24.1

Pathway Developmental Biology; Fatty acid, triacylglycerol, and ketone body metabolism; Gene Expression; Generic Transcription Pathway; Metabolism; Metabolism of lipids and lipoproteins; PPARA Activates Gene Expression

Function DNA binding; RNA polymerase II transcription cofactor activity; transcription coactivator activity; transcription factor binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]