Published OnlineFirst June 15, 2017; DOI: 10.1158/2326-6066.CIR-16-0381 Title: A Four-Factor Immunoscore System that Predicts Clinical Outcome for Stage II/III Gastric Cancer Running Title: Immunoscore as Prognostic Model for Gastric Cancer Ti Wen1†PhD., Zhenning Wang2†MD., Yi Li3 MD., Zhi Li1 MD., Xiaofang Che1 PhD., Yibo Fan1 MD., Shuo Wang1 MD., Jinglei Qu1 MD., Xianghong Yang5 MD., Kezuo Hou1BS., Wenyang Zhou5 MS., Ling Xu1 MD., Ce Li1 MS., Jin Wang1 MD., Jing Liu1 MD., Liqun Chen3BS., Jingdong Zhang4 MD., Xiujuan Qu1* MD., Yunpeng Liu1* MD. 1 Department of Medical Oncology, Key Laboratory of Anticancer Drugs and Biotherapy of Liaoning Province 2 Department of Surgical Oncology and General Surgery, The First Hospital of China Medical University, No.155, Nanjing North Street, Heping District, Shenyang, 110001, China 3 Department of Pathology, 4 Department of Medical Oncology, Cancer Hospital of Liaoning Province, No.44, Xiaoheyan Road, Dadong District, Shenyang, 110042, China 5 Department of Pathology, Shengjing Hospital of China Medical University, No.36, Sanhao Street, Heping District, Shenyang, 110004, China *Corresponding Author: Yunpeng Liu, MD. PhD., Tel/Fax: +86-(0)24-83282312; E-mail:
[email protected] and Xiujuan Qu, MD. PhD. Tel/Fax: +86-(0)24-83282312; E-mail:
[email protected]; Department of Medical Oncology, The First Hospital of China Medical University, No.155, Nanjing North Street, Heping District, Shenyang 110001, China; †These two authors contributed equally to this work. Keywords: gastric cancer, immunoscore system, PD-L1, PD-1, CD8, prognostic model Grant Support This work was supported by Key National Science and Technology Major Project of China (No.