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DED UN 18 O 98 F http://www.nesacs.org N Y O T R E I T H C E N O A E S S S L T A E A C R C I N S M S E E H C C TI N O CA February 2009 Vol. LXXXVII, No. 6 N • AMERI Monthly Meeting Professor Wilton L. Virgo of Wellesley College to Speak at Simmons College Tips for Job Seekers By Megan Driscoll Summer Scholar Report Identification of Genes Regulated by Transcriptional Regulator, p8 By Derek Kong This Month in Chemical History By Harold Goldwhite, California State University, Los Angeles February Historical Events in Chemistry by Leopold May, The Catholic University of America, Washington, DC February 1, 1905 methods for the determination of ing and used it against pellagra and Fifty years ago, Emilio Segré shared crystal structures, was born on this pursued the idea that diseases such the Nobel Prize in Physics (1959) day. as beriberi, scurvy, rickets and pella- with Owen Chamberlain for their gra were caused by lack of vital sub- discovery of the antiproton. He co- February 16, 1955 stances in the diet. discovered technetium with C. Per- F. P. Bundy, H. T. Hall, H. M. Strong rier in 1937, and astatine with D. R. and R. H. O. Wentoff announced the February 25, 1880 Corson and R. MacKenzie in 1940, synthesis of diamonds at General Arthur B. Lamb, who was the editor and demonstrated the existence of Electric Research Laboratories on of the Journal of the American the antiproton in 1955. He was born this date. Chemical Society (1917-1949), was born on this day. on this date. February 19, 1859 February 2, 1802 One hundred and fifty years ago, February 28, 1901 Jean Baptiste Boussingault, who Svante A. Arrhenius was born. He Linus C. Pauling, who was born on demonstrated that plants absorb devised a theory of electrolytic dis- this date, received the Nobel Prize nitrogen from soil in the form of sociation and was a researcher in for Chemistry in 1954 for his nitrates and not from air as previ- viscosity and reaction rates. In 1903 research into the nature of the chem- ously believed, was born on this day. he was awarded the Nobel Prize in ical bond and its application to the Chemistry in recognition of the elucidation of the structure of com- February 6, 1892 extraordinary services he had ren- plex substances and the Nobel Peace Seventy-five years ago, William P. dered to the advancement of chem- Prize in 1962. He did research on Murphy shared the Nobel Prize in istry by his electrolytic theory of the structure of molecules such as Physiology or Medicine (1934) with dissociation. proteins and investigated the con- George R. Minot & George H. cepts of valency and resonance. February 23, 1884 Whipple for their discoveries con- Additional historical events can be cerning liver therapy in cases of One hundred and twenty-five years ago Casimir Funk was born. He iso- found at the CSW website or Dr. anemia. He was born on this date. May’s website, faculty.cua.edu/may/ lated nicotinic acid from rice polish- N February 7, 1834 history.htm. One hundred and seventy-five years ago Dimitri I. Mendeleev was born. He discovered the Periodic Law (Table) at same time as Lothar Meyer, who published later. February 8, 1795 One hundred and seventy-five years ago Friedlieb F. Runge discovered carbolic acid (phenol) and aniline in coal tar. He also investigated dry distillation and the composition of matter and was born on this date. February 12, 1826 Moritz Traube, who was born on this date, did research in semi-per- meable membranes, sugars, respira- tion, fermentation, oxidation, protoplasm, and muscle. February 14, 1917 Herbert A. Hauptman, who devel- oped methods for the determination of crystal structures and received the Nobel Prize in 1985 with Jerome Karle for their outstanding achieve- ments in the development of direct 2 The Nucleus February 2009 The Northeastern Section of the American Chemical Society, Inc. Contents Office: Marilou Cashman, 23 Cottage St., Natick, MA 01360. 1-800-872-2054 February Historical Events in Chemistry 2 (Voice or FAX) or 508-653-6329. ____________________ e-mail: mcash0953(at)aol.com by Leopold May, Catholic University of America Any Section business may be conducted Notable New England Chemists 4 via the business office above. NESACS Homepage: ___________________________ http://www.NESACS.org Eben Horsford, Wolcott Gibbs, Josiah Cooke, Jr. and Thomas Hunt David Cunningham, Webmaster Monthly Meeting 5 ACS Hotline, Washington, D.C.: _______________________________________ 1-800-227-5558 Professor Wilton L. Virgo, Wellesley College, to Speak At Simmons College Officers 2009 Announcements 6 Chair: ________________________________________ Dr. E. Joseph Billo NSYCC Event-Overcoming Barriers in Careers in Chemistry and Chemical Sci- 13 Shattuck Street ences Natick, MA 01760 508-653-3074, joseph.billo(at)verizon.net Call for Nominations 6 ____________________________________ Chair-Elect: John McKew James Flack Norris Award for Outstanding Achievement in the Teaching Of Wyeth Research Chemistry, Philip L. Levins Memorial Prize 200 Cambridge Park Drive This Month in Chemical History 7 Cambridge, MA 02140 ___________________________ Immediate Past Chair: By Harold Goldwhite, California State University, Los Angeles Marietta Schwartz Summer Scholar Report 8 Chemistry Department, UMass-Boston Boston, MA 02125 _________________________________ 617-287-6146; marietta.schwartz(at)umb.edu Identification of Genes Regulated by Transcriptional Regulator, p8 Secretary: By Derek Kong, Sandro Goruppi and John Kyriakes, Molecular Cardiology Michael Singer Research Institute, Tufts University, Medford, MA Sigma-Aldrich Tips for Job Seekers in a Contracting Environment 11 3 Strathmore Rd., Natick, MA 01360 __________ 508-651-8151X291; msinger(at)sial.com By Megan Driscoll, Pharmalogics Recruiting Treasurer: James Piper 2009 Chair’s Statement 11 19 Mill Rd., Harvard, MA 01451 _______________________________ 978-456-3155, piper28(at)attglobal.net Correction: E. Joseph Billo’s Actual 2009 statement! Auditor: Photos from National Chemistry Week 12 Anthony Rosner ____________________ Archivist: By Morton Z. Hoffman Myron S. Simon Cover: 20 Somerset Rd. Professor Bassam Shakhashiri (University of Wisconsin-Madison), Newton, MA 02465; 617-332-5273 Phyllis A. Brauner Memorial Lecturer at the Boston Museum of Science during Romysimon(at)mindspring.com Trustees: National Chemistry Week (Photo by Morton Z. Hoffman) Joseph A. Lima, Esther A. H. Hopkins, Deadlines: Michael E. Strem April 2009 Issue: February 13, 2009 Councilors Alternate Councilors May 2009 Issue: March 13, 2009 Term Ends 12/31/2009 Catherine Costello Julia H.Miwa Patricia Mabrouk Alfred Viola Michaeline F. Chen Jerry P. Jasinski Dorothy J. Phillips Eva B. Binnun Amy Tapper Barney Grubbs The Nucleus is published monthly, except June and August by the Northeastern Section of the American Term Ends 12/31/2010 Chemical Society, Inc. Forms close for advertising on the 1st of the month of the preceding issue. Text Thomas R. Gilbert Timothy B. Frigo must be received by the editor six weeks before the date of issue. Pamela Nagafuji Mark Froimowitz Robert Lichter David Cunningham Editor: Michael P. Filosa, Ph.D., ZINK Imaging, Inc., 16 Crosby Drive, Building 4G, Michael Singer Erik Rozners Bedford, MA 01730 Email: Michael.filosa(at)zink.com; Tel: 508-843-9070 Term Ends 12/31/2011 Associate Editors: Myron S. Simon, 20 Somerset Rd., W. Newton, MA 02465, Tel: 617-332-5273 Doris I. Lewis C. Jaworek-Lopes Sheila E Rodman, Konarka Technologies, Inc., 116 John St. Suite 12, Lowell, Mary Burgess Patrick M. Gordon MA 01852 email:srodman(at)konarka.com tel 978-569-1414 Morton Z. Hoffman Lawrence Scott Assistant Editors: Stefan G. Koenig, Mindy Levine Michael P. Filosa Donald Rickter Kathi Brown Liming Shao Board of Publications: David Cunningham (Chair), Mary Mahaney, Vivian K. Walworth Business Manager: Karen Piper, 19 Mill Rd., Harvard, MA 01451, Tel: 978-456-8622 All Chairs of standing Advertising Manager: Vincent J. Gale, P.O. Box 1150, Marshfield, MA 02050, Committees, the editor Tel: 781-837-0424 of THE NUCLEUS, and Contributing Editors: Morton Hoffman, Feature Editor; Dennis Sardella, Book Reviews the Trustees of Section Calendar Coordinator: Sheila Rodman, email: srodman(at)konarka.com Funds are members of the Board of Directors. Any Photographers: Morton Z. Hoffman and James Phillips Coun cilor of the American Chemical Society Proofreaders: Donald O. Rickter, Myron S. Simon, Vivian K. Walworth, E. Joseph Billo, residing within the section area is an ex officio Webmaster: David Cunningham, webmaster(at)nesacs.org member of the Board of Directors. Copyright 2008, Northeastern Section of the American Chemical Society, Inc. The Nucleus February 2009 3 American Academy of Arts and Sci- Notable New ences. He was deeply interested in the Corporate Patrons ($2000+) chemistry of foods, an interest shown Abbott Bioresearch by many articles, his book on “Theory Genzyme England Lyophilization Service of New England and Art of Breadmaking” (1861), and Merck the development of processes for man- National ACS Chemists ufacturing condensed milk and baking Novartis powder. Pfizer From Myron S. Simon Schering Corporation Here we continue with the short biog- Wolcott Gibbs Sepracor raphies by Lyman C. Newell and Ten- 1822-1908 Serono Reproductive Institute ney L. Davis of Noted New England Wolcott Gibbs was the son of an enthu- Vertex Pharmaceuticals chemists of bygone days. siastic mineralogist. He was born in Wyeth Pharmaceuticals New York City and received the Bach- Eben Norton Horsford Patrons ($1000-$1999) elor’s degree from Columbia Univer- Aptuit 1818-1893 sity in 1841. He then served for a time Astra-Zeneca R&D Boston Eben Norton Horsford was born in as an assistant to Robert Hare in Broad Institute Moscow, NY. He graduated from the Philadelphia. In 1845 he was awarded Creagen Biosciences Rensselaer Polytechnic Institute as a the degree of Doctor of Medicine by Estate of Wallace Gleekman civil engineer in 1838.