Annual Report

ANNUAL REPORT

2004

Northeastern Section American Chemical Society

Local Section Name: Northeastern Section URL for Total Report: http://www.nesacs.org

Prof. Jean A. Fuller-Stanley Chair 2004 Northeastern Section, ACS

2 TABLE OF CONTENTS (Pages numbered separately by section) Pages PART I - QUESTIONNAIRE

Annual Report Questionnaire ...... 7

PART II: ANNUAL NARRATIVE REPORT

Activities: National Chemistry Week ...... 17 Phyllis A. Brauner Memorial Lecture...... 17 Northeast Student Chemistry Research Conference (NSCRC) ...... 18 Northeast Regional Undergraduate Day...... 18 Undergraduate Environmental Research Symposium ...... 18 Connections to Chemistry ...... 19 NESACS Vendor Fair and Medicinal Chemistry Symposium...... 19 NESACS Fundraising Booklet19...... 19 ACS Scholars Program...... 20 Summary...... 20 2004 Goal Attainment 2004 Local Section Goals and Assessment ...... 22 2004 Chair's Goals and Assessment...... 22 2005 Goals...... 23 Suggestions / Concerns...... 23 ACS Strategic Thrusts...... 24

PART II - APPENDICES 1-5

APPENDIX 1 - SUPPORTING DOCUMENTS FOR ACTIVITIES

Supporting Documents for Activities National Chemistry Week ...... 27 Phyllis A. Brauner Memorial Lecture...... 33 Northeast Student Chemistry Research Conference (NSCRC) ...... 37 Northeast Regional Undergraduate Day...... 39 Undergraduate Environmental Research Symposium ...... 41 Connections to Chemistry ...... 43 NESACS Vendor Fair and Medicinal Chemistry Symposium...... 46 NESACS Fundraising Booklets...... 52 ACS Scholars Progra ...... 60

APPENDIX 2 - BUDGETS AND LONG-RANGE PLAN

Report of the Treasurer ...... 64 2-A: Budget for 2004 ...... 65 Budget for 2005 ...... 66 2-B: Long-Range Plan...... 68

APPENDIX 3 - MEMBERSHIP SURVEYS AND 2004 NEWSLETTER

3-A: Membership Survey Conducted in 2004 ...... 74 3-B: 2004 Newsletter...... 74 April, 2004 issue of The Nucleus uploaded to ACS online report (S.O.L.A.R.)

APPENDIX 4 - PUBLIC RELATIONS PLAN - TALKS TO PUBLIC - NEWSPAPER CLIPPINGS

4-A: Public Relations Plan ...... 76 4-B: Talks to Public...... 78 4-C: Press Release / Hill Award...... 80

APPENDIX 5 - AS NEEDED BY SECTION: NESACS REPORTS

Officers, Councilors, Directors, and Committee Chairs 2004 ...... 83 Calendar of Activities 2004...... 89 Reports: Archivist...... 92 Awards Committee...... 93 Awards Presented by the Northeastern Section ...... 102 Brauner, Phyllis A. - Memorial Lecture...... 103 Constitution & Bylaws Committee ...... 106 Continuing Education Committee ...... 106 Corporate Funding...... 110 Education Committee ...... 115 Education Committee / High School Subcommittee ...... 123 Esselen Award Committee...... 137 Government Relations Committee...... 145 Local Arrangements Committee...... 146 Long-Range Planning ...... 146 Medicinal Chemistry Group ...... 151 Membership Committee ...... 159 National Chemistry Week Committee...... 162 NERM 2004 ...... 164 Nominating Committee...... 165 Norris Award Committee...... 166 Professional Relations Committee ...... 173 Program Committee / Chair-Elect...... 174 Public Relations Committee...... 175 Public Service Committee / Elementary Education Task Force...... 177 Publications, Board of...... 178 Richards Medal Committee...... 184 Speakers' Bureau ...... 187 Summerthing 2004 ...... 188 Treasurer ...... 191 Trustees, Board of ...... 191

APPENDIX 5-A: Highlights of 2004 Section Meetings in Pictures ...... 194

APPENDIX 5-B: Programs and Publications

Northeast Student Research Conference...... 204 Connections to Chemistry...... 219 Undergraduate Research Symposium at Bridgewater State College...... 231 Employment Guide for ACS Members...... 236

APPENDIX 6 - YOUNGER CHEMISTS COMMITTEE

Report of the Younger Chemists Committee ...... 250

PART III - ANNUAL FINANCIAL REPORT

Part A: Statement of Revenues and Expenses Operating Fund ...... 260 Part B: Balance Sheet as of 12/31/04...... 260 Addendum to Financial Report filed online with ACS...... 261

PART IV - SELF-NOMINATIONS FOR CHEMLUMINARY AWARDS

Outstanding Performance by Local Sections ...... 263

Outstanding Local Section Younger Chemists Committee...... 266 Outstanding or Creative Local Section Younger Chemists Committee Event...... 268

Outstanding On-going NCW Event ...... 270 Outstanding Event for the General Public Using the Yearly Theme Award...... 272 Best Student Affiliate Event...... 275

Annual Report Northeastern Section

PART I

ANNUAL REPORT QUESTIONNAIRE

http://www.nesacs.org

6 PART I - QUESTIONNAIRE

Part I - Annual Report Questionnaire REQUIRED

Northeastern

Save and Mark Form as Complete Save Changes Main Menu Printable Version

Please provide your answers in the form below. You may save your work and return to this form at any time by clicking "Save Changes". Once you have completed this form, please click "Save and Mark Form as Complete".

****Important Notice Please Read****

The EZ form consists of the Part I - Questionnaire, Part III - Financial Report and the Optional Part IV - Self- Nomination Form for ChemLuminary Awards. Sections that wish to submit the EZ form are not required to submit the Part II - Narrative and Appendices. All local sections are eligible to complete the EZ form UNLESS, they would like to self-nominate themselves for the LSAC Award for Outstanding Performance by a Local Section. Local sections may submit the EZ form and self-nominate themselves for any of the other awards listed in Part IV. Local Sections must postmark or submit their completed annual reports electronically by February 15, 2005 to be eligible for any of the awards

We do not wish to be considered for the Local Section Outstanding Performance Award

*Part I Annual Report Questionnaire *Part II Annual Report Narrative and Appendices (Optional) *Part III Financial Report *Part IV Self Nomination for ChemLuminary Awards (Not Eligible for Local Section Outstanding Performance Award (Optional)

Our section would like to be considered for the ACS Local Section Outstanding Performance Award. We are submitting Parts I,II,III and IV of the annual report

*Part I Annual Report Questionnaire * Part II Annual Report Narrative& Appendices * Part III Financial Report * Part IV Self Nomination for ChemLuminary Awards (***Outstanding Performance Award Nomination must be completed***)

Web Posting of Annual Reports

Our Section would like to have Parts I and II (if applicable) posted on the Local Section Activities Committee website.

1. Top Activities

Please list the titles of your top activities (in rank order) and indicate if the activity was new in 2004. Check if new in 2004 Title of Activity 1. National Chemistry Week

7 2. Phyllis A. Brauner Memorial Lecture 3. Northeast Student Chemistry Research Conference 4. Northeast Regional Undergraduate Day 5. Undergraduate Environmental Research Symposium 6. Connections to Chemistry

7. NESACS Vendor Fair and Medicinal Chemistry Symposium

8. NESACS Fundraising Booklets 9. ACS Scholars Program 10.

2. Section Administration

EXECUTIVE COMMITTEE 10 2.1 How many times did the executive committee meet during 2004? 67 2.2 How many members are on the executive committee? 9 2.3 How many section meetings were held in 2004? 88 2.4 On average, how many members attend regular section meetings?

COUNCILORS What percentage of the section's Councilors were in official attendance at the ACS spring Council 100 2.5 meeting? % What percentage of the section’s Councilors were in official attendance at the ACS fall Council 86 2.6 meeting? %

2.7 How do Councilors report to the section about national ACS matters? (check all that apply)

at a section meeting at an executive committee meeting

in the newsletter on the local section website

COMMITTEES 2.8 Specify active committees having two or more members.

Awards Newsletters/Publications

Budgets/Finance Nominations

Career Assistance Professional Relations

Chemistry Olympiad Project SEED

Continuing Education Public Relations

Education Senior Chemists

Environmental Environmental Health and Safety/ Chemical Hygiene

8 Government Affairs Women Chemists

Industry Relations Younger Chemists

Local Arrangements Long-Range Planning Other

Constitution & Bylaw s Membership/Member Retention Other

Brauner Memorial Lecture Mentoring Other

Corporate Funding Minority Affairs Other

National Chemistry Week

SUBSECTIONS 0 2.9 How many subsections are active in the section? 0 2.10 How many subsection meetings were held in 2004?

TOPICAL GROUPS 1 2.11 How many topical groups are active in the section? 3 2.12 How many topical group meetings were held in 2004?

OPERATIONS AND PLANNING (Check all that apply)

2.13 The section prepared a budget for 2004 (Please include a copy in Part II Appendix 2)

2.14 The section prepared a budget for 2005 (Please include a copy in Part II, Appendix 2)

2.15 The section prepared a long-range plan (Please include a copy in Part II, Appendix 2) The section maintains and uses a current job manual prepared by the section as a guide for officers 2.16 and committees. The section conducted a membership survey in 2004 to determine member's interests and needs 2.17 (Please include a copy in Part II, Appendix 3)

2.18 A section representative attended the ACS Leaders Conference (Local Section Leaders Track) in 2004.

SECTION COMMUNICATION How many newsletters were published in 10 2.19 2004? One copy of a newsletter is included in 2.20 Appendix 3. How many meeting notices were published 37 2.21 in 2004? URL: http://w w w .nesacs.org

2.22 The section has an active website.

9 2.23 The section used electronic communication. The section posted its 2003 Annual Report 2.24 on its website.

SECTION ELECTIONS 553 2.25 How many members voted in the 2004 officer election?

SECTION AWARDS (check all that apply) The section submitted a nomination for the ACS Regional Award in High School Chemistry Teaching 2.26 during 2004.

The section gave awards or a Salutes to Excellence to:

2.27 Primary school students (K-6)

2.28 Secondary school students (7-12)

2.29 College students

2.30 Primary school teachers (K-6)

2.31 Secondary school teachers (7-12)

2.32 College teachers

2.33 Members of the local section for service

2.34 Outstanding chemist(s), regardless of section affiliation

The section or local company encouraged and/or submitted a nomination for the ACS Regional Industrial 2.35 Innovation Awards.

SECTION AFFILIATES How many paid section affiliates excluding students (teachers, technicians, others) are there 24 2.36 in the section?

2.37 Section has supported an existing Technician Affiliate Group (TAG)during 2004.

2.38 Section has promoted the formation of a Technician Affiliate Group during 2004

REGIONAL MEETINGS

2.39 Does your local section have a representative to your Regional Board/Steering Committee?

3 - 8 ACS Strategic Plan Core Strategies

CORE STRATEGY #1 Provide Timely State-of-the-Art Chemical Information(Check all that apply)

3.1 The section organized a regional meeting.

An ACS Technical Division was involved.

3.2 The Section organized a symposium.

10 An ACS Technical Division was involved.

3.3 The organized a Meeting-in-Miniature.

An ACS Technical Division was involved.

3.4 The section organized an undergraduate research symposium.

An ACS Technical Division was involved.

3.5 The section organized a meeting that was co-sponsored by an ACS Technical Division.

CORE STRATEGY #2 Serve as the Premiere Professional Organization for Practitioners of Chemistry (Check all that apply)

4.1 The section provided services for pre-college students.

4.2 The section provided speakers for student affiliate chapter meetings.

4.3 The section organized tours of local industries for student affiliate chapters.

4.4 The section offered financial support for student affiliate chapter activities. The section offered financial support to students attending regional or national meetings undergraduate 4.5 or graduate

4.6 The section appointed a member as student affiliate chapter liiaison The section members served as non faculty professional advisors or contacts for students and young 4.7 chemists

4.8 The section provided students with free subscriptions to journals.

4.9 The section invited student affiliates to attend regular section meetings.

4.10 The section sponsored a teacher affiliate group to engage students in ACS.

4.11 The section involved student affiliates in National Chemistry Week activities.

4.12 The section distributed career literature to students or to college and universities.

CORE STRATEGY #3 Enhance the Public Appreciation of the Chemical Sciences and Technologies (Check all that apply)

5.1 Providing Judges for area science fair(s)

5.2 Sponsoring awards at area science fair(s)

5.3 Members make visits to K-12 classrooms.

5.4 Presenting career programs and/or distributing career literature to students or schools Sponsoring or organizing student competitions (e.g., chemistry examinations, Chembowls, poster 5.5 competitions)

11 5.6 Presenting Chemical Demonstrations

5.7 Participating in US National Chemistry Olympiad

The section encourages paticipation and leadership in all aspects of the chemical sciences by women (W) underrepresented minorities (M) and persons with disabilities (D) (Check all that apply) W M D

5.8 Section members mentored students or colleagues

5.9 The section sponsored hands-on science activities in underserved communities.

5.10 The section provided summer research opportunities. The section developed science career fairs at high schools or colleges that have high 5.11 female, minority or disabled populations.

5.12 The section organized summer science camps.

5.13 The section sponsored contests or awards.

5.14 The section maintained employment services

Local section members interacted with federal government officials (i.e., members of congress, agency 5.15 staff, etc.) to encourage funding of research

5.16 The section maintained an experts roster and provided it to local media.

5.17 The section created or updated a media list.

5.18 The section prepared a public relations plan and included a copy of this plan in Appendix 4. How many times were section activities promoted to the local media (press releases, op-eds, 5.19 advisories, etc.)? 24

5.20 The section used an ACS film, videotape, or other ACS visual-aid resource at a public event. 5.21 How many talks were given by section members to the public in 2004? 52 The section conducted a chemical hygeine, responsible care or environmental health and safey 5.22 event for the general public. The section offered its services to the local community as a resource on chemical hygeine, 5.23 responsible care or environmental health and safety.

5.24 The section carried out environmental activities for the general public.

5.25 The section participated in or conducted the following community activities:

Chemists Celebrate Earth Day Chemists in the Library

Chemagination Contest NCW

NCW Youth Patch Activity Program

5.26 The section conducted the following activities during NCW 2004:

12 Chemical Hands-on activities Demonstrations

Lectures Contests or games or training Other UG Day & Connections to Chem

5.27 The section's NCW Activities were carried out in the following venues:

K-8 schools High Schools Colleges or Universities

Industrial Sites Museum/Libraries Shopping Malls

Other

5.28 The section worked with the following group(s) to produce NCW events:

K-8 schools High Schools Colleges or Universities

Industry Museums or Libraries Scout Troops

Civic Orgnizations

Other

5.29 The section publicized NCW via:

Newspapers/magazines/flyers Radio Television Website

5.30 The section participated in the NCW unifying event in 2004. 2 5.31 What is the total number of year that the NCW coordinator has served in this capacity?

5.32 The section has a Government Relations Representative.

5.33 The section invited state or federal government officials to speak at a local section meeting. The section organized or participated in a special government relations event(state capitol day, science 5.34 town meeting, legislative hearing, public policy forum, etc.). The section informed its members on legislative issues and events through newsletter article, website, 5.35 or other communications method.

5.36 The section member(s) held an office or key position in state or federal government in 2004.

CORE STRATEGY #4 Transform the Defination of Chemistry to Encompass Its True Multidisciplinary Nature

6.1 The section has topical groups in interdisciplinary areas.

6.2 The section has sponsored meetings with an interdisciplinary focus.

13 The section offered activities such as symposium, seminars, or sponsored student activities on 6.3 environmental issues.

CORE STRATEGY #5 Deliver a Dynamic and Integrated Porfolio of Products and Services. (Check all that apply)

7.1 The section published articles on employment services in its newsletter or website.

The section sponsored local employment services (e.g., free ads in section newsletter or website, job 7.2 counseling, employment clearing house)

7.3 A section representative attended a Local Section Career Program during 2004

7.4 The section referred individuals to national ACS Department of Career Services.

7.5 The section maintained a job line for positions available within the local section.

7.6 The section hosted an ACS short course. 7.7 How many local section career programs or activities were conducted in 2004? 21 7.8 Of the local section programs that were conducted in 2004, how many were new? 8

7.9 The section offered career counseling/literature.

CORE STRATEGY #6 Promote Inclusiveness Throughout the Chemical Enterprise (Check all that apply)

8.1 Conducting teacher workshops

8.2 Inviting teachers to attend section meetings.

8.3 Providing teachers with free subsciptions to magazines and journals

8.4 Involving teachers in section program planning

8.5 Participation in Project SEED

8.6 Presenting a forum to address educational issues The section offered specifically tailored symposium, seminars, or sponsored activities for industrial 8.7 chemical professionals.

8.8 Industrial members are active in the section's governance The section communicated with non-ACS members working in industry and local companies about 8.9 meetings and programs.

8.10 Local companies have financially-sponsored and activity or donated money to the section.

8.11 Industrial members (M), local companies (C), and/or non-members employed in industry (N) participated in these section programs or activities. M C N

Meeting at industrial site/plant tour

Local Section Award/Recognition program

Membership Drive for new members

14 Industrial speaker/Industrially focused topic

NCW or community activities

Career Development activities

Student or younger chemist activities

The section is affiliated with other technical or scientific 8.12 societies or consortia. 8.12a If the section has a formal affiliation with

(Name of organization)

This affiliation was approved by ACS council in what year The section held a meeting jointly with another professional 8.13 organization.

ACS STRATEGIC PLAN 2004 - 2006 The American Chemical Society Strategic Plan focuses on the commitments to our Science, our profession and the Public. The plan sets forth a bold course that builds on the traditional strengths of the society and concentrates on emerging needs and opportunities. The plan focuses on six core strategies that the Society will pursue to lead and support the chemical enterprise into the future. For more information on the ACS Strategic Plan, please visit chemistry.org

ANNUAL REPORT Northeastern Section, ACS

PART II

ANNUAL NARRATIVE REPORT

http://www.nesacs.org

16 PART II - NARRATIVE

Form: Part II - Annual Narrative Report Optional for EZ Submission Organization: Northeastern Year: 2004

A. Activities Please describe and rank up to ten of your section's activities during 2004. Provide (a) the title of the activity, (b) a one paragraph description of the activity, and (c) an indication of which ACS Strategic Thrusts. Please refer to the end of this section for a listing of the ACS Strategic Thrusts or see Part I, questions 3-12. If you wish to provide details beyond these paragraphs, please do so in Appendix 1.

Activity #1 a) Title: National Chemistry Week b) Description (Please limit to one paragraph)

On Sunday, October 17, 2004 the Phyllis A. Brauner Memorial Lecture held at the Wellesley College Science Center signaled kick-off activities for the Northeastern Section’s National Chemistry Week. Two lecture- demonstrations (at 11:00 a.m. and 2:00 p.m.) were performed by Dr. Jerry Bell (ACS, formerly at Simmons College) and Dr. Jim Golen, (UMass-Dartmouth). In keeping with the National theme, “Celebrating Chemistry - Health and Wellness,” numerous student affiliate chapters provided participatory educational, yet fun, activities for close to 300 children of “all ages.” Additionally, Tufts University’s Dental Smile Squad provided hands-on demonstrations in proper brushing of teeth as well as free toothbrushes and other samples. This venue also marked the kick-off of Mole Day activities (ten individuals, each with ten mole-stickers, finding ten people to get ten more, etc.,) organized by the Simmons College student affiliate. The mole-sticker activities continued throughout the week and culminated on October 23, (Mole Day). This significantly demonstrated the enormity of the mole as a quantitative concept. Over 5000 individuals participated. The Wellesley College Science Center’s unique design was a natural complement to the NCW activities and many visited the College’s Greenhouses to view some medicinal plants. c) Which Strategic Thrust(s) does this activity support? (Please refer to the List of Strategic Thrusts) 1 2 3 4 5 6 (No) This activity was new in 2004

Activity #2

Title: Phyllis A. Brauner Memorial Lecture b) Description (Please limit to one paragraph)

The late Dr. Phyllis A. Brauner was an active and dedicated member of the faculty of Simmons College and Framingham State College and served as a Past-Chair of the NESACS, Editor of The Nucleus, Councilor, and Trustee and was a recipient of the Henry A. Hill Award for Outstanding Service to the Northeastern Section. The NESACS established the Phyllis A. Brauner Memorial Lecture Endowment in 2002 to support this lecture annually during National Chemistry Week. A Phyllis A. Brauner Memorial Book Award is also presented annually at the Northeast Student Chemistry Conference to the student who gives the best talk or poster c) Which Strategic Thrust(s) does this activity support? (Please refer to the list of Strategic Thrusts) 1 2 3 4 5 6 (No) This activity was new in 2004

17 Activity #3 a) Title The Northeast Student Chemistry Research Conference (NSCRC) b) Description (Please limit to one paragraph)

The Sixth Annual Research Conference was held April 24, 2004 at Boston University and was jointly organized by the Education Committee of the Northeastern Section ACS and the Younger Chemists Committee of the Northeastern Section. This conference brought together undergraduates, graduate students and post-doctoral fellows in a venue where they were able to interact with each other and share results of their chemistry investigations through oral and poster presentations. Additionally, this year German students from the on-going exchange between the Jungchemikerforum (JCF) of the Gesellschaft Deutscher Chemiker (GdCh) and the Younger Chemists of NESACS also participated in the conference activities. Dr. Charles Casey, National ACS President 2004, gave the welcoming remarks and Dr. Stephen Lippard of MIT gave the keynote address. There were 6 oral presentations by students--3 undergraduate and 3 graduate students. Additionally, over 90 students representing a wide variety of institutions presented posters of their research. Prizes were awarded for the best oral presentations and best posters in a variety of categories. c) Which strategic thrust(s) does this activity support? (Please refer to the list of Strategic Thrusts) 1 2 3 4 5 6 (No) This activity was new in 2004

Activity #4 a) Title: Northeast Regional Undergraduate Day b) Description (Please limit to one paragraph)

The 13th Annual Northeast Regional Undergraduate Day sponsored by the Education Committee and hosted by the Student Affiliate of Boston University was held November 6, 2004 at B.U. This was one of many activities celebrating National Chemistry Week. Nearly 150 individuals representing colleges and universities from Massachusetts, Rhode Island, Connecticut, New York and Vermont participated in a myriad of activities. Topics ranged from: Résumé Review & Choosing a Graduate School to seminars on such topics as Synthesis and Applications of Biodendrimers & Making Things from Light. c) Which Strategic Thrust(s) does this activity support? (Please refer to the list of strategic thrusts.) 1 2 3 4 5 6 (No) This activity was new in 2004

Activity #5 a) Title: Undergraduate Environmental Research Symposium b) Description (Please limit to one paragraph)

The 3rd Annual Undergraduate Environmental Research Symposium was held November 6, 2004 at Bridgewater State College (BSC), and was co-sponsored by the Education Committee of NESACS. Undergraduate and graduate research projects were the main focus of the symposium; however, there was special emphasis on the environmental issues of particular concerns to Southeastern Massachusetts, the location of BSC. Over 40 students’ research posters in all sectors of environmental research were presented from students representing a wide variety of academic institutions from the northeastern United States. The keynote address was given by Dr. Bill Freedman from Dalhousie University, Halifax, Nova Scotia. c) Which Strategic Thrust(s) does this activity support? (Please refer to the list of Strategic Thrusts) 1 2 3 4 5 6 (No) This activity was new in 2004

18 Activity #6 a) Title: Connections to Chemistry b) Description (Please limit to one paragraph)

The Fifth Annual Connections to Chemistry program – to connect high school chemistry teachers to the educational resources of the ACS and in particular to members of the Northeastern Section was held October 13, 2004 at Burlington High School, MA. This unique program attracted over 140 teachers from 83 different high schools in Massachusetts, New Hampshire, Connecticut, Rhode Island and Maine. This year’s activities included workshops on a variety of chemistry-related topics including Bonding and Molecular Graphics by Frank Gorga of Bridgewater State College and The Real CSI Lab by a Forensic Chemist at the MA State Police Crime labs. The program culminated with an after-dinner talk titled Vampires, Rockets and the Hot Zone – Confronting Emerging Infectious Diseases (Mark Klempner M.D.). Raffle items included subscription to J. Chem. Educ., affiliate memberships in CHED & ACS software. Additionally all participants were awarded certification for professional development credits as well as a year’s subscription to ChemMatters and a year’s associate membership in the NESACS. c) Which Strategic Thrust(s) does this Activity Support? (Please refer to the list of Strategic Thrusts. 1 2 3 4 5 6 (No) This activity was new in 2004

Activity #7 a) Title: NESACS Vendor Fair and Medicinal Chemistry Symposium b) Description (Please limit to one paragraph)

The first NESACS Vendor Fair was organized by the Fund Raising Committee and held September 9, 2004 at the Radisson Hotel, Woburn, MA. This was held in conjunction with the Medicinal Chemistry Symposium and Career Workshop. Over 12 exhibitors participated in this event which led to increased revenue for the Section’s activities and programs. Given the success of this first Vendor Fair, plans are underway to make this an annual event. c) Which strategic Thrust(s) does this activity support? (Please refer to the list of Strategic Thrusts). 1 2 3 4 5 6 (Yes) This activity was new in 2004

Activity #8 a) Title NESACS Fund Raising Booklets b) Description (Please limit to one paragraph)

The focus of the NESACS Fundraising Committee was to have a broader outreach and to appeal to a wider donor base. The committee, in consultation with NESACS Board, decided to highlight the Section’s programs and activities in the form of booklets to be sent to potential donors. In order to make the fundraising plans as effective as possible, Chairs of committees were asked to write a paragraph and/or provide pictures that best described what their activities and programs entailed. The Fundraising Committee compiled and edited the information into two brochures that were printed in color and bound to better appeal to particular sponsors. One brochure was specifically on the ACS Scholars program and the other on NESACS activities. These brochures and other fundraising activities substantially increased contributions to the Section. c) Which strategic Thrust(s) does this activity support? (Please refer to the list of Strategic Thrusts). 1 2 3 4 5 6 (Yes) This activity was new in 2004

19 Activity #9 a) Title: NESACS / ACS Scholars Program b) Description (Please limit to one paragraph)

The Section renewed its financial commitment to the ACS Scholars program in 2004 by pledging $2500 each year for the four years (2004-2007) to a worthwhile and necessary program. Additionally, the Section invites all ACS Scholars attending academic institutions within our Section to attend monthly meetings and dinner as guests of the section. Despite a short notice, many ACS Scholars attended the February meeting where they were able to participate in the Section’s honoring of one of its oldest and most active member, Arno Heyn. The ACS Scholars attending that meeting were also able to meet and be greeted by then President-elect 2004, William Carroll. A good time was had by all. c) Which strategic Thrust(s) does this activity support? (Please refer to the list of Strategic Thrusts). 1 2 3 4 5 6 (No) This activity was new in 2004

B. Summary - Overall Section Activities

Please summarize in 1,000 words or less, the activities of the section in 2004 which have not been already described. Outstanding events should be described in some detail and appropriate attachments included in Appendix 1. Programs described here may be featured in publications produced by the ACS Membership Division and/or at the Local Section Leadership Conferences.

It was an honor and a privilege to serve as Chair of the Northeastern Section of the American Chemical Society (NESACS) in 2004. My overall theme, if there was one, was rekindling the spirit of active participation and active involvement. As one of the largest (and growing) sections of the ACS we have close to 20% attendance by members at our monthly meetings. Our Section organized and sponsored a significant number of lectures, programs and activities during 2004 for members, non-members and the community at large. The Chair’s opening statement in the Section’s newsletter, (The Nucleus, January 2004) urged greater member involvement. Additionally, sign-up sheets for committee volunteers were handed out at each meeting. Theses strategies proved to be very effective in getting members to volunteer for committees.

The Section is fortunate in being financially well-endowed and, with a revitalized Fund Raising Committee, we were able to continue to provide a wide variety of programs and services for members and the community. The fund raising committee was centralized and incorporated members from Younger Chemists Committee and the medicinal chemistry group. The Section engaged in long-term planning and integrated the Medicinal Chemistry Group fully into the Section’s programs. Our National Chemistry Week events at Wellesley College and continuing at different venues in the Greater Boston area involved over 5000 individuals.

The Membership Committee sent letters to the more than a thousand new members of the Section, inviting them to the monthly meetings as the Section’s guest at the dinner that precedes the lecture. Attendance at the meetings of the Board of Directors which precedes the monthly meetings had excellent attendance. Additionally the Social Hours preceding the monthly dinners and talks were lively and provided excellent networking opportunities. Ten monthly meetings of the Executive Committee were held; our June Board meeting was dedicated to Long-Range Planning.

Employment initiatives: Recognizing the changing nature of chemistry in particular, the increased emphasis on interdisciplinary acumen and emergence and importance of the biotechnology industries,

20 particularly within the geographic locale of the Northeastern Section and the increasing unemployment (and underemployment) of Section members, a Career workshop targeting mid-career chemists was organized as part of the September monthly meeting. This was well attended and focused on how to reorganize one’s resume as well as an emphasis on the need to be flexible and to see chemistry and the skills acquired as being transferable to these emerging related areas. The feedback has been very positive and the Section certainly intends to repeat this workshop in the near future. In addition, the Northeastern Section Younger Chemists organized a Student Career Fair which included workshops on resume writing and interviewing skills. This also included a Job Fair where students were able to meet with representatives from local companies. Additionally, an Employment Guide was published in the Nucleus and job listings were posted on the Section’s website.

During 2004, the Section sponsored and presented the James Flack Norris Award in Physical Organic Chemistry to Dr. C. Dale Poulter at the Spring 2004 ACS National Meeting in Anaheim, CA. In addition, the Section presented the following awards: Theodore W. Richards Medal to Dr. John Ross (Professor Emeritus Stanford University) for Conspicuous Achievement in Chemistry. Gustavus J. Esselen Award to Dr. James W. Jorgenson (Professor, University of North Carolina at Chapel Hill) for Chemistry in the Public Interest. The James Flack Norris Award for Outstanding Achievement in the Teaching of Chemistry was also awarded to Dr. Richard N. Zare (Professor, Stanford University). The Henry A. Hill Award for Outstanding Service to the Northeastern Section was presented to Dr. Donald O. Rickter (retired) at the October meeting.

The Section is very proud of both the quality and timeliness of our monthly newsletter, The Nucleus. We have also had the good fortune to have had continuity in the editorship of Arno Heyn for nearly 15 years. Unfortunately due to ill health, Arno was forced to resign at the end of 2003 as editor of The Nucleus. Thus the Section underwent a period of transition while we searched for a new editor. Again we are fortunate and grateful that we have members who willingly volunteered as Interim Editors to take up the challenge of keeping the publication on time as well as maintain the high standards we had come to expect under Arno’s editorship.

Finally, another area that underwent significant revamping and transition was that of the Public Relations Committee. Due to relocation and family commitments, our new co-chairs of this revitalized committee had to resign. However, the Section was fortunate to find a young capable volunteer who is eager to get involved and make things happen. As a result, the Section anticipates much more interaction with the media about our events, activities and members’ accomplishments.

To summarize, the Section had a successful year in 2004 and was able to continue to provide both technical and professional service to its members while at the same time connecting to the next and future generation of chemists and informed citizens through its various programs. For our activities in 2003, the Section was named award finalist for ChemLuminary Awards in the following categories at the National Meeting in Philadelphia in August 2004: Committee on Community Activities – Most Original Hands-On Activity or Chemical Demonstration, YCC - Outstanding Local Section Younger Chemists Committee and Outstanding Local Section Younger Chemists Committee Event. Even though we did not win any of the awards, we are proud of the service we have provided and continue to provide for members and non- members alike.

We are proud of our accomplishments throughout the year and of all our members who worked so hard to accomplish our goals and to provide programs and activities of benefit to members of the Northeastern Section and the community at large.

C. Local Section and Chair Goals

1. 2004 Goal Attainment. The Local Section Activities Committee strongly encourages local section planning. As a result, the 2004 local section annual report should follow-up on the attainment of goals. Please list the goals you set at the beginning of your term for your section and yourself, and report on the attainment of the goals. a) 2004 Local Section Goals and Assessment: 1. Goal: Revitalize the Public Relations Committee to increase media coverage of the Section’s activities, especially our NCW, Education and monthly meetings programs. Assessment: Membership on this committee was increased and two new co-chairs emerged. Despite losing our new co-chairs due to relocation and increased family commitments, the Section’s media coverage increased during 2004. Plans are currently underway for updated media contacts and early publicity for our activities.

2. Goal: Increase the membership on Section’s committees; assign members to committees based on information from the informal feedback sheets. Assessment: Sheets were handed out at each monthly meeting and members were asked to list committees they were interested in both learning more about and or serving on. This was very successful in expanding membership on a number of committees, such as Public Relations, Professional Relations, Local Arrangements and Membership.

3. Goal: Reduce Section’s expense for monthly meetings by seeking different and less costly host sites for monthly meetings. Assessment: This continues to be a goal to strive for. While we were able to achieve some reduction in the cost for venues, this still remains an area of high priority.

4. Goal: Alter the general content and aesthetics of the Section’s newsletter, The Nucleus; increase the number of photographs depicting attendees at Section’s activities. Assessment: This was achieved; many issues of the Nucleus for 2004 have an increased number of photographs of section activities.

b) 2004 Chair's Goals and Assessment:

1. Goal: Conduct membership survey to better ascertain Section members’ needs Assessment: This was not achieved. A comprehensive survey was not done, however, informal feedback was solicited from members attending monthly meetings, with regard to committees of interest and programs and activities of interest.

2. Goal: Increase integration of sub-groups (i.e., Medicinal Chemistry Group) in our Section Assessment: This goal was met. The MCG programs used to be separate from the Section and funds were allocated to their activities somewhat grudgingly. The MCG is now fully integrated into the Section and fundraising is now coordinated through one central committee. Additionally, to increase the number of opportunities and to satisfy the increasing demands for topics related to medicinal chemistry, the September monthly meeting has now become the venue for the Fall Medicinal Chemistry Symposium and Vendor Fair. This was very successful in 2004 and will continue for the foreseeable future. Attendance at these MCG symposia has increased the visibility of Section activities to our industrial chemists.

22 3. Goal: Broaden Section’s fundraising solicitation to include Chemistry and Non-Chemistry agencies. Assessment: This goal was achieved. The preparation of the Section’s new Fundraising booklets has enabled us to present a summary of the Section’s programs and activities to a wide audience of potential donors.

4. Goal: Provide more printed information and workshops targeted to middle-aged unemployed or under-employed Section chemists to increase their marketability. Assessment: This goal was achieved. At the September 2004 monthly meeting, in addition to the Vendor Fair and MCG Symposium, the Section held the first Mid-Career Workshop. This was over-subscribed and feedback was positive. Additionally, more information about job opportunities was posted on the Section’s website as well as e-mail sent to members who indicated they were seeking employment.

a) 2005 Local Section Goals (Include at least three goals):

1. Completely redesign the NESACS website with emphasis on the employment link. Ensure that the website maintains current information. Set up a NESACS mailing list link. 2. Recruitment of younger chemists, student affiliates, high school teachers, and industrial chemists for attendance at monthly meetings and participation on NESACS committees. 3. Promote financial support from industry b) 2005 Chair’s Goals:

1. Start a Northeastern Section Women’s Chemist Committee 2. Organize four networking /social events 3. Hold a golf tournament co-sponsored by the WCC. This event will be used for social / networking as well as a fundraising event for the Section.

D. Suggestions/Concerns

List any suggestions you have for the Local Section Activities Committee (LSAC). How can LSAC specifically help your section?

The Local Section Leadership Conferences have been extremely valuable as a springboard for new chairs- elect and chairs. I think it is crucial that this leadership conference continue in the same or a slightly modified format. The Northeastern Section still needs help with getting more members from the industrial sector to participate at the level of chair-elect.

Listing of Strategic Thrusts

Please refer to the numbers below when identfiying activities as they relate to the ACS Core Strategies 1 Providing Timely State-of-the-Art Chemical Information. 2 Serving as a Premier Professional Organization for Practioners of Chemistry. 3 Elevating Public Appreciation of Chemical Sciences and Technologies. 4 Changing the Defination of Chemistry to Encompass its True Multidisciplinary Nature. 5 Delivering a Dynamic and Integrated Portfolio of Products and Services. 6 Promoting Inclusiveness throughout the Chemical Enterprise. For more information on the Core Strategies or the ACS Strategic Plan 2004-2007 please visit www.chemistry.org.

ANNUAL REPORT Northeastern Section, ACS

PART II - APPENDIX 1

SUPPORTING DOCUMENTS FOR ACTIVITIES

http://www.nesacs.org

25 APPENDIX 1 - SUPPORTING DOCUMENTS FOR ACTIVITIES

APPENDIX 1 - CONTENTS Supporting Documentation for Part II - Narrative

Activity 1 - National Chemistry Week ...... 27 Report from NCW Chair ...... 27 From NESACS Calendar of Activities...... 28 Sample Items from The Nucleus...... 29 Program Schedule - Undergraduate Day ...... 30 Poster and Flyer from Connections to Chemistry Program...... 31 Activity 2 – Phyllis A. Brauner Memorial Lecture...... 33 Report from the Brauner Lecture Committee...... 33 Invitation Letter to Wellesley College Lecture...... 34 Excerpt from the National Chemistry Week Report...... 35 Items from The Nucleus...... 35 Excerpt from the NCW ChemLuminary Award Self-Nomination...... 35 Activity 3 – Northeast Student Chemistry Research Conference...... 37 Report from Education Committee...... 37 Report from YCC ...... 37 Sample Item from The Nucleus / Call for Papers ...... 38 NSCRC Program (See Appendix 5-B for total program) ...... 38 Activity 4 – Northeast Regional Undergraduate Day...... 39 From the Education Committee Report...... 39 From The Nucleus – Preliminary Announcement...... 39 Undergraduate Day Program...... 40 Activity 5 – Undergraduate Environmental Research Symposium...... 41 From the Education Committee Report...... 41 Symposium Announcement / Bridgewater State College web site...... 42 See Appendix 5-B for Symposium Program ...... 42 Activity 6 – Connections to Chemistry ...... 43 From the Education Committee Report...... 43 From the NESACS Calendar of Activities ...... 44 See Appendix 5-B for the total Connections to Chemistry program...... 44 From The Nucleus / schedule of activities...... 45 Activity 7 – NESACS Vendor Fair and Medicinal Chemistry Group Symposium...... 46 Excerpt from Report of Committee on Corporate Funding...... 46 From the NESACS Calendar of Activities ...... 46 Item from The Nucleus ...... 46 Vendor Fair Poster...... 47 Program of Activities / List of Vendors ...... 48 Medicinal Chemistry Group Flyer...... 51 Activity 8 – NESACS Fundraising Booklets...... 52 Excerpt from Report of Committee on Corporate Funding...... 52 Letter to Potential Donors ...... 52 Booklet mailed to potential donors...... 53 Activity 9 – ACS Scholars Program...... 60 Reference to Fundraising Booklet related to Scholars Program...... 60 Excerpt from Education Committee Report ...... 60 Commitment of NESACS to ACS Scholars Program ...... 60 Invitation to ACS Scholars...... 61

26 SUPPORTING DOCUMENTATION: ACTIVITY 1

NATIONAL CHEMISTRY WEEK

Report from NCW Chair

REPORT OF NATIONAL CHEMISTRY WEEK - 2004 Christine Jaworek-Lopes, Chair

On Sunday, October 17, 2004, the Northeastern Section of the American Chemical Society and Wellesley College sponsored and hosted a 2004 National Chemistry Week celebration focusing on the yearly theme Health and Wellness. For weeks before the celebration, volunteers from Emmanuel College, Simmons College, Suffolk University, Tufts University, and Wellesley College worked out the details of numerous demonstrations and hands- on activities. More than 60 volunteers (from Clark University, Emmanuel College, Simmons College, Suffolk University, Tufts University, Wellesley College) ensured that the more than 250 visitors to the day-long event enjoyed a number of hands-on activities and demonstrations relating to the theme.

These activities included: • making UV detectors (bracelets) using UV-sensitive beads and comparing the effectiveness of sunscreens; • isolating iron from Total® cereal; • demonstrating proper hand-washing techniques using a Glo Germ kit; • demonstrating the importance of insulin to regulate blood sugar; • the Urine the Know activity taken from “Celebrating Chemistry – Health and Wellness, p. 5”; • demonstrating how a glucose meter works; • demonstrating how dental sealants work and how acidity affects teeth.

The Tufts Dental Smile Squad was on hand for the day to demonstrate how to effectively brush teeth.

Among the highlights of the day were the lecture demonstrations as part of the Phyllis A. Brauner Memorial lectures presented by Dr. Jerry Bell of the American Chemical Society, Dr. William Dills of UMASS Dartmouth, and Dr. James Golen of UMASS Dartmouth. These captivating lectures were enjoyed by children and adults alike.

Throughout the week, Simmons College educated individuals about the enormity of the mole at a variety of locations including the Wellesley kick-off event, Simmons College, Emmanuel College, and at the Museum of Science in Boston. This was accomplished by first giving ten individuals a sticker, each numbered one through ten. Each of these ten individuals was given ten additional stickers to give out to ten more people. If any of the “stuck” people returned to the Mole Day table throughout the week they would receive ten stickers as well and information about the mole. To visualize this, a stunning pipe cleaner display was arranged in which each of the original branches were linked together and attached were the people that stickers went out to. One pipe cleaner represented one individual, which made it easy to see the enormity of how many people were reached yet how far from a mole this really was. Over 5000 individuals participated in this event. For partaking in this event, each individual’s number was entered into a free raffle which included various gift certificates and prizes from places around Boston.

In September 2004, more than 250 public and private schools were informed of the Northeastern Section’s participation in the NCW poster competition via a mass mailing. Although the number of participating schools was low (two schools, 14 participants), two posters were sent onto the NCW Office of Community Activities. The creators of the winning posters were: Tayla Thomes (K-2 entrant) and Lori Merlo (3rd-4th grade entrant). Each participant in the poster competition received a notepad, a pencil, and a certificate. The two winners also received T-shirts for their accomplishments.

Throughout the week, volunteers from local schools and industries assisted hundreds of visitors in the week-long celebration in appreciation of chemistry in the world around us.

27 From NESACS Calendar of Activities

Oct-Nov 2004 National Chemistry Week Activities October 17 Phyllis A. Brauner Memorial Lecture / Wellesley College Science Center Dr. Jerry Bell, ACS & Dr. Jim Golen, University of Massachusetts Dartmouth Theme: Health and Wellness! Hands-on Activities related to Health and Wellness November 6 Thirteenth Annual Northeast Regional Undergraduate Day / Boston University Keynote Speaker: Prof. Matthew D. Shair, Harvard University Topic: From Biology-Inspired Organic Synthesis to Organic Synthesis for Studying Biology Research Talks & Seminar Prof. Mark Grinstaff, Boston University Synthesis and Aplications of Biodendrimers Dr. Antony Wright, Strem Chemicals Navigating a Chemistry Career to Include Employment within a Commercial Enterprise Prof. Alex Golger, Boston University Demonstrations in Chemistry to Fascinate Kids Prof. Scott Schaus, Boston University Choosing a Graduate School Dr. Frank Wagner, Strem Chemicals Preparing Your Resume Graduate School and Industry Fair Prof. John Fourkas, Boston College Making Things with Light Dr. Adam Yeager, Boston University Development of Chemical Libraries Using Parallel Synthesis Prof. Anthony Fernandez, Merrimack College Resuscitating a Shallow-Breathing Student Affiliates Chapter November 6 Third Annual Undergraduate Environmental Research Symposium / Bridgewater State College Keynote Speaker: Dr. Bill Freedman, Dalhousie University, Halifax, Nova Scotia Environmental Impacts of Forest Harvest Practices in Canada

28 From The Nucleus

29 Program Schedule - Undergraduate Day

30 From the Connections to Chemistry Program

Workshops

National Chemistry Week

Celebrate National Chemistry Week October 17-23, 2004

National Chemistry Week (NCW) provides an opportunity for your students to share the fun and relevance of chemistry with members of their school and neighborhood communities. It also provides a way for them to share in a nation-wide celebration of Chemistry. Teachers can participate in NCW by holding events that focus on celebrating this year’s theme Health and Wellness. The October issue of ChemMatters, the ACS magazine for high school students, contains articles and activities that reflect this theme. ChemMatters can be accessed on line at . The October issue of the Journal of Chemical Education also features articles about the chemistry of Health and Wellness, and lists numerous resources

As part of the National Chemistry Week 2004 celebration, the Northeastern Section of the American Chemical Society (NESACS) will sponsor a daylong program at Wellesley College on Sunday, October 17, 2004. Chemistry demonstrations and hands-on activities related to Health and Wellness will be featured at the Wellesley Science Center. Guests for these activities will include the Tufts Dental Smile Squad. A special presentation of chemical demonstrations will be given by Dr. Jerry Bell and Dr. Jim Golen at 11 AM – noon and repeated at 2 PM.; the presentations are free; seating is on a first-come, first-served basis. The official announcement for this program is included at the end of this program.

For more information on the National Chemistry Week programs for the Northeastern Section, go to .

SUPPORTING DOCUMENTATION: ACTIVITY 2

BRAUNER MEMORIAL LECTURE

From the Brauner Committee Report

As agreed by the Northeastern Section and the ACS, the Phyllis A. Brauner Lecture is held in the Northeastern Section’s territory in conjunction with National Chemistry Week and named in memory of Dr. Brauner. As envisioned and established by Phyllis, and presented by the Northeastern Section since 1986, the Lecture will be for the general public of all ages. In addition to assisting with the annual presentation of the Lecture, the Committee is charged with establishing a trust that will support the Lecture. Since the Lecture is a participant in National Chemistry Week, contributions may be matched through the ACS Matching Gift Fund Program, subject to the conditions of this program and to continuing support of this program by the ACS. The endowment goal is a $150,000 endowment fund with income supporting the lectures.

The committee met jointly with the NCW Committee in September. Activities of the Committee this year were centered around organizing the 2004 Phyllis A. Brauner Lecture. This year the lecturers were Jerry Bell, currently with the education division of the American Chemical Society, and formerly a colleague of Phyllis’ at Simmons College, and Jim Golen of UMass-Dartmouth, who for years has been delighting children in the Northeastern Section with his demonstrations. Again this year the site of the lecture was Wellesley College, Phyllis’ alma mater; the date was Sunday, October 17. The beautiful campus was an ideal setting for the Lecture and for the hands-on activities for youngsters led by area college chemistry students based on the National Chemistry Week 2004 Theme, Health and Wellness. The Northeastern Section web site www.nesacs.org features the National Chemistry Week activities, and, under the NCW link, the web site of the Brauner Lecture (look for the Brauner Lecture logo).

Brauner Fund Report – 2004 (Submitted by NESACS treasurer Jim Piper)

2004 Cash gifts $2380.50 Cash gifts from operating account that did not appear in the 12/31/04 Smith Barney statements - $493.50 Value of the Brauner Memorial Account $21,474.04 Brauner portion of the Consolidated Account: 2.0771% of $1,742,524.09 or $36,193.97. Total Brauner Funds: 58,161.51 Income portion $2605.53; the remainder is principal.

Respectfully submitted, Doris I. Lewis, Chair

Invitation to Attend Lecture

N ORTHEASTERN SECTION AMERICAN CHEMICAL SOCIETY

PHYLLIS A. BRAUNER MEMORIAL LECTURE COMMITTEE

DR. DORIS I. LEWIS PHONE: (617) 573-8546 SUFFOLK UNIVERSITY FAX: (617) 573-8668 41 TEMPLE STREET [email protected] BOSTON, MA 02114

October 6, 2004

Dear Friend of the Phyllis A. Brauner Lecture,

I am writing on behalf of the Phyllis A. Brauner Lecture Committee to inform you of our current activities and to invite you to join us in attending and supporting this year’s Lecture. This year the lecturers will be Jerry Bell, currently with the education division of the American Chemical Society, and formerly a colleague of Phyllis’ at Simmons College, and Jim Golen of UMass-Dartmouth, who for years has been delighting children in the Northeastern Section with his demonstrations Again this year the site of the lecture will be Wellesley College, Phyllis’ alma mater, and the date is Sunday, October 17. The beautiful campus is a wonderful setting for the Lecture and for the hands-on activities for youngsters led by area college chemistry students. Please consult the enclosed brochure for details on this marvelous day of activities, the Northeastern Section's opening activity for National Chemistry Week. We have held a limited number of tickets for Friends of the Lecture; just contact Marilou Cashman as described on the enclosed flyer. If you would like to help out with the day’s activities, you’re cordially invited to do so; just contact me. You are invited as well to visit the Northeastern Section web site at www.nesacs.org to view the National Chemistry Week activities, and particularly, under the NCW link, to view the web site of the Brauner Lecture (look for the Brauner Lecture logo).

Additionally, I am pleased to report that the Northeastern Section donation, personal donations, corporate matches, and ACS matching funds have brought the total at this time to over $50,000. We continue to seek individual, corporate, and foundation support toward our goal of $150,000, and are appreciative of donations or of suggestions of appropriate sponsors. Under current American Chemical Society guidelines, donations of $3000 or more paid over a period of three years or less are eligible for a match on a 50% basis. Establishing the Brauner Trust as a Northeastern Section Trust has ensured the continuation of the Phyllis A. Brauner Lecture, a lasting memorial to Phyllis, bringing the excitement of chemistry to the public of all ages.

Sincerely yours,

Doris I. Lewis, Chair Phyllis A. Brauner Memorial Lecture Committee [email protected] 617-573-8546

Phyllis A. Brauner Memorial Lecture Committee Inka Allen Michaelene Chen Sarah Iacobucci Katherine O’Sullivan Steven Allen Dudley Hershbach Ann Jenkins Bassam Shakhashiri Catherine Brauner Arno Heyn Doris I. Lewis Carolyn Spodick Susan Brauner Esther A. H. Hopkins Julianna Lovell Valerie Wilcox

From the NCW Report

From The Nucleus

From the NCW ChemLuminary Self-Nomination

Description of the Activity: Name of the Activity/Program: Phyllis A. Brauner Memorial Lecture Date Conducted: Sunday, October 17, 2004 Location of the Event: Wellesley College

Number of Participants: Number of ACS members involved: 50 Approximate size of audience reached: 275

35 chemistry at Northeastern University as well as Swarthmore College; she was a professor of chemistry at Simmons College for 34 years. Actively involved in the Northeastern Section of the American Chemical Society, Phyllis was chair of the Section in 1974, a Member of the Board of Directors, a Councilor of the Section, a Trustee, and the Editor of The Nucleus.

“Over the years, Phyllis organized numerous lectures featuring chemistry educators, such as Hubert Alyea, Jerry Bell, and Dudley Herschbach. The lectures have always been free to the public and have drawn enthusiastic audiences of all ages.”2 In 1986, Phyllis played an integral role in starting a Holiday Lecture Series at the Museum of Science. Professor Bassam Shakhashiri presented the inaugural lecture on December 29, 1986.

“In commemoration of Phyllis’ lifetime of work the Northeastern Section of the ACS has instituted the annual Phyllis A. Brauner Memorial Lecture to be held during National Chemistry Week.”3 On November 4, 2001, the first memorial lecture was held at the Museum of Science in Boston. Professor Bassam Shakhashiri presented a lecture entitled Picasso, Da Vinci, Shakhashiri: Artistry and Chemistry. Approximately 400 individuals attended this free lecture.4 On October 20, 2002, Professor Bassam Shakhashiri regaled audiences at the Museum of Science- Boston with a Phyllis A. Brauner Memorial Lecture entitled “Quest for Chemistry: Moles, Molecules, and Mummies.” Once again, approximately 400 individuals attended this free lecture. The third memorial lecture was held on October 19, 2003 at Wellesley College; approximately 350 individuals attended the lecture-demonstrations performed by Professor Bassam Shakhashiri. Highlights of the lecture included: the methanol cannon and demonstrations of complete vs. incomplete combustion reactions. The fourth memorial lecture was held on October 17, 2004 at Wellesley College; approximately 275 individuals attended the lecture-demonstrations performed by Dr. Jerry Bell of the American Chemical Society, Dr. William Dills of UMASS Dartmouth, and Dr. James Golen of UMASS Dartmouth. Highlights of the lecture included showing that air, a gas, is a substance that takes up space; testing breath for a substance that is acidic and causes limewater to get cloudy, demonstrating the non-flammability of carbon dioxide, and demonstrating some of the properties of hydrogen, oxygen, and hydrogen-oxygen mixtures. Over the years, these captivating lectures were enjoyed by children and adults alike.

This lecture was the centerpiece of a day of hands-on activities featuring volunteers of all ages from retired chemists to student affiliates and involving participants from preschoolers through high school. This year’s event at Wellesley College featured the five student affiliate chapters participating in a single NESACS NCW event, with approximately 50 SAACS students sharing the chemistry of health and wellness with demonstrating the importance of insulin in blood sugar regulation, isolating iron from cereals, demonstrating proper hand-washing techniques using a Glo Germ Kit all while sporting the popular NCW tattoos. Volunteers were treated to an informal lunch with Dr. Bell, Dr. Dills, and Dr. Golen in a brief break from the day’s whirlwind of activities.

For the last four years, the Northeastern Section of the American Chemical Society and either the Museum of Science or Wellesley College has co-sponsored these lectures. These popular lecture demonstrations have been performed to capacity-filled lecture halls for the last three years. This event has become a highlight of the Northeastern Section’s National Chemistry Week Kick-off Event.

SUPPORTING DOCUMENTATION: ACTIVITY 3

NORTHEAST STUDENT CHEMISTRY RESEARCH CONFERENCE

from the Education Committee report:

Held at Boston University on April 24, 2004, the sixth annual Research Conference brought together undergraduates, graduate students and post-doctoral fellows from the northeastern region of the country for the purpose of celebrating their accomplishments in research, and for providing a forum for the sharing of ideas and scientific understanding. In addition, this year included German students from the on-going exchange between the Jungchemikerforum (JCF) of the Gesellschaft Deutscher Chemiker (GdCh) and the Younger Chemists and undergraduate students of NESACS. Welcoming remarks were given by Dr. Charles Casey, National ACS President 2004; the keynote address, New Fluorescent Sensors to Study Biochemical Zinc and Nitric Oxide and to Monitor Mercury in the Environment was given by Dr. Stephen Lippard of MIT.

In addition to the research poster presentations, there were 6 student presentations: 3 undergraduate student speakers and 3 graduate student speakers. The presenting students and their institutions were: Filiz Aslan, Boston University: Engineering Reduced-Size Streptavidin Mutants Sebastian Fritzsche, University of Leipzig: Early-Late Heterobimetallic Salen Complexes as Catalysts for Selective Epoxidation Elisa Miller, Boston University: Chemical Dynamics of High Energy Molecules Pasha Mirazimi, Boston College: Development of Models for the Synamics of Oligomeric DNA through Solid State Nanopore Channels: Prospects for Ultrarapid DNA Sequencing Mingfend Yang, Clark University: Mapping Early Steps of Amyloid Formation with Computational Approaches Christian Ducho, University of Hamburg: CycloSal Pronucleotides – Chemical Trojan Horses with Antiviral Activity

A presentation of the Phyllis Brauner Undergraduate Book Award was made to Elisa Miller from Boston University for her research paper given above.

From the YCC Annual Report

Northeast Student Chemistry Research Conference, NSCRC (April 24)

The sixth annual Northeast Student Chemistry Research Conference was held at Boston University’s Photonics Center on April 24 this year. Approximately 120 participants joined us for the event, a 50% increase over last year’s attendance. Of these 120, 80 presented posters during the afternoon poster session.

The conference began with an address from Dr. Charles Casey. Dr. Casey welcomed the younger chemists attending the NSCRC, talked about his research, and asked students for their opinions and concerns for the future of chemistry. Six research talks by selected students followed these welcoming remarks; two were given by German visitors. After the oral presentations, a buffet luncheon was served to the attendees and the poster session began.

This year, we had 10 judges at the NSCRC who walked around and questioned students about their posters and research. Among these were Dr. Casey, our very own Chair, Dr. Jean Fuller-Stanley and

37 our Immediate Past-Chair, Dr. John Neumeyer. After the poster session, Dr. Stephen Lippard of MIT gave an excellent Keynote Address entitled “New Fluorescent Sensors to Study Biochemical Zinc and Nitric Oxide and to Monitor Mercury in the Environment.”

Awards were then given out to the students for the best oral and poster presentations. Strem Chemicals, Inc. gave a monetary award for the Best Oral Presentation, which went to Christian Ducho of the University of Hamburg. Genzyme gave monetary awards for the Best Poster Presentations. These went to Christopher Dicesare (Tufts University), Supratim Datta (Boston University), and Jamie Ryan (Boston University). The Brauner Undergraduate Book Award went to Elisa Miller of Boston University. Kluwer also donated books as prizes for the conference. These prizes went to William Neeley (MIT), Frank Sischerl (University of Konstanz), Lourdes Pia H. Lopez (MIT), Melanie Schnell (University of Hannover), Nathan Maugel (Merrimack College) and Aaron Gregory Schmidt (Emmanuel College).

The NSYCC met its goals this year in the planning of the NSCRC. We improved the attendance, held the conference in a much larger, more attractive venue and were able to award cash prizes to students for their posters and talks. For the first time, we also had posters designed by a graphic artist advertising the conference (and Career Fair), which we mailed to area universities. Next year, we hope to increase attendance further and move the conference to a different university to enhance diversity. We would also like to increase the amount of cash prizes awarded.

From The Nucleus

NSCRC Program

The complete NSCRC Program taken from the NESACS web site may be found in Appendix 5-B of the NESACS Annual Report.

38 SUPPORTING DOCUMENTATION: ACTIVITY 4

NORTHEAST REGIONAL UNDERGRADUATE DAY from the Education Committee report

Thirteenth Annual Northeast Regional Undergraduate Day (Coordinated by Matthew Vigneau, Kevin Burgoyn and Morton Hoffman and Hosted by Chemia, SAACS at Boston University)

The 13th annual Northeast Regional Undergraduate Day sponsored by the Education Committee was held on November 6, 2004 at Boston University in conjunction with National Chemistry Week Activities. The registrants numbered more than 135 representing colleges and universities from Massachusetts, Rhode Island, Connecticut, New York, and Vermont. The keynote address, From Biology-Inspired Organic Synthesis to Organic Synthesis for Studying Biology, was given by Prof. Matthew Shair from Harvard University.

Small group topics and seminars followed that included: Choosing a Graduate School (Prof. Scott Schaus, Boston University) Demonstrations in Chemistry to Fascinate Children (Prof. Alex Golger, Boston University) Resumé Review (Dr. Frank Wagner, Strem Chemicals) Reviving a Shallow-Breathing SA Chapter (Prof. Anthony Fernandez, Merrimack College) Making Things with Light (Prof. John Fourkas, Boston College) Navigating a Chemistry Career to Include Employment within a Commercial Enterprise (Dr. Anthony Wright, Strem Chemicals) Synthesis and Applications of Biodendrimers (Prof. Mark Grinstaff, Boston University) Development of Chemical Libraries Using Parallel Synthesis (Dr. Adam Yeager, Boston University)

A graduate school and industry fair provided students with the opportunity to obtain information from representatives of universities and industries. A nominal registration fee was charged to offset the costs of refreshments, lunch and materials. The Undergraduate Day was a National Chemistry Week activity, and was sponsored by the NESACS Education Committee.

From The Nucleus

Undergraduate Day Program

40 SUPPORTING DOCUMENTATION: ACTIVITY 5

UNDERGRADUATE ENVIRONMENTAL RESEARCH SYMPOSIUM

from the Education Committee report

The Third Undergraduate Environmental Research Symposium. Sponsored by the Education Committee of the Northeastern Section ACS et al., Bridgewater State College

The Education Committee of NESACS co-sponsored the Third Annual Undergraduate Environmental Research Symposium held on Saturday, November 6, 2004 at Bridgewater State College. The symposium focuses on undergraduate and graduate research projects, with a special emphasis on environmental issues of particular concern to Southeastern Massachusetts. Over 40 student research posters in all areas and disciplines of environmental research from colleges and universities in the northeastern United States were submitted. The Symposium is intended to provide a forum for discussion on environmental research and concerns and possibly open doors to potential research collaborations. The keynote address, Environmental Impacts of Forest Harvest Practices in Canada, was given by Dr. Bill Freedman from Dalhousie University in Halifax, Nova Scotia. Two poster sessions were held immediately following Dr. Freedman’s talk

Attendees were treated to a continental breakfast, and to lunch. Assistance with registration and poster set-up was provided by the Bridgewater State College ACS Student Affiliate. In addition to NESACS, financial assistance was provided by the Bridgewater State College Adrian Tinsley Program for Undergraduate Research and by the NCUR/Lancy Initiative, a program that provides resources to undergraduates who show promise of exceptional achievement.

From Bridgewater State College web site

Environmental Research and Teaching

Third Annual Undergraduate Environmental Research Symposium Bridgewater State College Saturday, November 6, 2004 9:00 AM - 3:00 PM John Joseph Moakley Center

Symposium Program!

Abstracts of Poster Presentations!

Guest Speaker: Dr. Bill Freedman Department of Biology and School for Resource and Environmental Studies Dalhousie University, Halifax, Canada

Symposium Program Directions to the Moakley Center

Poster Titles & Abstracts 2004 BSC Campus Maps

Abstract Submission and Registration-closed Photo Gallery 2003

Contact Information Sponsors Announcement...... (PDF Poster here) The abstract submission deadline has passed.

SPONSORS Bridgewater State College Adrian Tinsley Program for Undergraduate Research The Canadian Studies Program Northeastern Section of the American Chemical Society

Please see Appendix 5-B for a list of presenters.

42 SUPPORTING DOCUMENTATION: ACTIVITY 6

CONNECTIONS TO CHEMISTRY

From the Education Committee Report

On October 13, 2004 NESACS sponsored Connections to Chemistry, a unique program to connect high school chemistry teachers to the educational resources of the ACS and to the members of the Northeastern Section. This is the fourth year for the program. Hosted by Burlington (MA) High School, the program drew over 140 teachers from 83 different high schools in Massachusetts, New Hampshire, Connecticut, Rhode Island, and Maine..

The high school chemistry teachers were welcomed to the program by Ruth Tanner (University of Massachusetts Lowell), Chair of the NESACS Education Committee and Chair of the Connections to Chemistry program. Steve Lantos, Chair of the High School Education SubCommittee (NESACS), welcomed his high school colleagues. He highlighted the ACS resources available for high school teachers, and encouraged them to utilize these resources. Morton Hoffman discussed the letter in their written program from Bill Carroll, the ACS President-Elect that encouraged the teachers to participate in a survey intended to gather data about a proposed associate membership in the ACS CHED for chemistry high school teachers. Survey cards were included.

Following the opening, workshops were offered to showcase the ACS resources for high school chemistry teachers and students: Four Simultaneous Workshops were offered in Two Sessions: Session I: 4:30 – 5:15 Session II: 5:25 – 6:10

Workshop A: Turn Them Into Writers Carolyn Collins Petersen, Science Writer and VP of Loch Ness Productions

Workshop B: The Real CSI Lab William Hebard, Forensic Chemist, Massachusetts State Police Crime Laboratory

Workshop C: Cows Eat Grass; People eat Pasta (NCW workshop) Edwin Jahngen, Biochemist, Department of Chemistry, University of Massachusetts Lowell

Workshop D: Bonding and Molecular Graphics Frank Gorga, Department of Chemical Sciences, Bridgewater State College (A two-session workshop, 4:30 - 6:10 PM)

The evening program included dinner and a talk titled Vampires, Rockets and the Hot Zone- Confronting Emerging Infectious Diseases by Mark Klempner, M.D., Director of the National Biocontainment Laboratories (National Center for Emerging Infectious Diseases and Biodefense) and Associate Provost of Research at Boston University’s Medical Campus.

Following his address, several items were raffled, including subscriptions to J. Chem. Educ., affiliate memberships in CHED, ACS Chemical Education Division CD’s and software, and several ACS logo products. To conclude the program, participants were given a certificate awarding professional development credits, a year’s subscription to ChemMatters, and a year’s associate membership in the Northeastern Section of the ACS.

The event received material assistance from the ACS, and publicity support from the New England Association of Chemistry Teachers, the Massachusetts Association of Science Supervisors, the Massachusetts Association of Science Teachers, Science Teachers Area Resources Swap and the New England Science Teachers. The Program Conference Committee also received planning and program support from the following:

Christine Jaworek, Chair, National Chemistry Week, NESACS; Emmanuel College Peter Nassiff, Past-Chair, NEACT; Head, Science Division, Burlington High School Arthur Fallon, Head, Media Services, Burlington High School Mark Malagodi, Computer Services, Burlington High School Nancy Spicer, Chemistry Faculty, University of Massachusetts Lowell Martin Isaks, Chemistry Faculty, University of Massachusetts Lowell James Hall, Director of Freshman Laboratories, University of Massachusetts Lowell

The Connections program received substantial material assistance from the ACS, and the editorial staff of the Journal of Chemical Education:

Lin Morris, Assistant Editor, Journal of Chemical Education Betty Moore, Associate Editor, Journal of Chemical Education Helen Herlocker, Manager, Office of High School Science, ACS, (ChemMatters) Robin Giroux, Assistant Managing Editor, Editing & Production, Chemical & Engineering News Denise Creech, Membership, Meetings and Expositions Head, ACS Staff John Clevenger, Chair, Division of Chemical Education, ACS Kevin McCue, Editor, ChemMatters, ACS

From the NESACS Calendar of Activities

October 13 Connections to Chemistry - High School Teacher Workshop - Burlington (MA) High School Workshop Sessions: A: Turn Them into Writers B: The Real CSI Lab C: Cows Eat Grass; People Eat Pasta D: Bonding and Molecular Graphics Program Speaker: Mark Klempner, MD National Center for Emerging Infectious Diseases and Biodefense & Boston University Topic: Vampires, Rockets and the Hot Zone – Confronting Emerging Infectious Diseases

The total program for Connections to Chemistry may be found in Appendix 5-B.

45 SUPPORTING DOCUMENTATION: ACTIVITY 7

NESACS VENDOR FAIR AND MEDICINAL CHEMISTRY SYMPOSIUM

From the Report of the Committee on Corporate Funding

The Fundraising Committee also organized the first vendor fair sponsored by NESACS, The fair was held with the Medicinal Chemistry Symposium on September 9, 2004. . . Fourteen companies participated with revenue of $5600.

From the NESACS Calendar of Activities

September 9 Monthly Meeting – Joint meting with Medicinal Chemistry Group Medicinal Chemistry Group Symposium – Radisson Hotel, Woburn, MA Topic: New Uses for Old Drugs Norton Peet, Aurigene Discovery Technologies, Lexington, MA Topic: Introductory Remarks George Muller, Celgene Corporation, Waren, NJ Topic: The Two Faces of Thalidomide Timothy Barberich, Sepracor, Marlborough, MA Topic: Evolution of the Improved Chemical Entity (ICE) Strategy Prof. Camille Wermuth, Université Louis Pasteur, Strasbourg, France Topic: New Leads from Old Drugs: The SOSA Approach September 9 NESACS Vendor Fair – Radisson Hotel, Woburn, MA September 9 Career Services Employment Seminar Resume Preparation – Mukund Chorghade Interviewing Skills – Arlene Wick Light Globalization Issues & Chemical Employment – Truman S. Light

From The Nucleus

46 Northeastern Section American Chemical Society Vendor Fair

Exhibit at the Medicinal Chemistry Symposium And Career Workshop Network with >100 Qualified Prospects Thursday, September 9, 2004 3-7 PM Radisson Hotel 15 Middlesex Canal Woburn MA

Three well-known speakers address “ New Uses for Old Drugs”

Professor, Camille G. Wermuth Faculte de Pharmacie, Universite Louis Pasteur, France

Dr. George W. Muller Sr. Director, Chemistry, Celgene Corporation

Mr. Timothy J. Barberich Chairman and CEO, Sepracor

Career Workshop for Mid-Career Chemists 2:30 PM

Cost: $400 per 6 foot table (address checks and mail to NESACS} Contact: Marilou Cashman, NESACS Office 23 Cottage St. Natick, MA 01760 1-800-872-2054 [email protected]

NORTHEASTERN SECTION

of the

AMERICAN CHEMICAL SOCIETY

SYMPOSIUM: New Uses for Old Drugs

CAREER WORKSHOP

VENDOR FAIR

September 9, 2004 Radisson Hotel Woburn, Massachusetts

PROGRAM

2:30 p.m. CAREER WORKSHOP for Mid-Career Chemists

3:00 – 7:00 p.m. VENDOR FAIR

SYMPOSIUM

3:30 p.m. Introductory Remarks Norton Peet Aurigene Discovery Technologies Lexington, MA

3:45 p.m. The Two Faces of Thalidomide George Muller Celgene Corporation Warren, NJ

4:45 p.m. Evolution of the Improved Chemical Entity (ICE) Strategy Timothy Barberich Sepracor Marlboro, MA

5:45 p.m. Social Hour and Dinner

7:45 p.m. 852ND MEETING, NORTHEASTERN SECTION, ACS Jean A. Fuller-Stanley Chair, Northeastern Section, presiding

New Leads from Old Drugs: The SOSA Approach Professor Camille Wermuth Université Louis Pasteur, Strasbourg, France

49 VENDOR FAIR EXHIBITORS

BIOTAGE FRED WINGERATH 1725 DISCOVERY DRIVE, CHARLOTTESVILLE, VA 29911

CHEMSILICO MARK HALL, MARC PARHAM 48 BALDWIN STREET, TEWKSBURY, MA 01876

DIONEX CORP. MIKE HUGHES, AZITA KAFFASHAN 1228 TITAN WAY, SUNNYVALE, CA 94088

ERLAB, INC. STEPHAN HAUVILLE 1980 TURNPIKE STREET, NORTH ANDOVER, MA 01845

ESA, INC. DAVE CLARK 22 ALPHA ROAD, CHELMSFORD, MA 01824

K-FORCE ALLISON OHRT, JEFF D’ITALIA 1001 EAST PALM AVENUE, TAMPA, FL 33605

PHASEX CORP. VAL KRUKONIS, KARA WILLIAMS 360 MERRIMACK STREET, LAWRENCE, MA 01843

STREM CHEMICALS, INC. MIKE STREM 7 MULLIKEN WAY, NEWBURYPORT, MA 01950

TOXICON CORPORATION FRED DECKERT, LARRY MILLER 15 WIGGINS AVENUE, BEDFORD, MA 01730

USFILTER DAVID HUGHES, DAVID YACIONELLO 10 TECHNOLOGY DRIVE, LOWELL, MA 01851

WATERS CORPORATION KIM HAYNES, ERNIE FAULKNER, 34 MAPLE STREET, MILFORD, MA 01757LINDA DEJESUS

WILMARK GROUP, INC. KELLY SCHUMACHER, AMY CREED 20 WILLIAM STREET, WELLESLEY, MA 02481

Note: Additional vendors were added after the programs were printed.

September Meeting

The 852nd Meeting Northeastern Section

of the American Chemical Society Northeastern Section of the American Chemical Society

Symposium: New Uses for Old Drugs

Organized by the Medicinal Chemistry Section of the Northeastern Section, American Chemical Society

Thursday - September 9th, 2004 Radisson Hotel - 15 Middlesex Canal - Woburn, MA

2.30 pm Refreshments 3.30 pm Introductory Remarks Norton Peet, Aurigene Discovery Technologies, Lexington, MA 3.45 pm The Two Faces of Thalidomide George Muller, Celgene Corporation, Warren, NJ 4:45 pm Evolution of the Improved Chemical Entity (ICE) Strategy Timothy Barberich, Sepracor, Marlborough, MA 5.45 pm Social Hour 6.30 pm Dinner 7.45 pm New Leads from Old Drugs: The SOSA Approach Professor Camille Wermuth, Université Louis Pasteur, Strasbourg, France

Dinner reservations should be made no later than 12:00 noon on Thursday, September 2, 2004. Please call Marilou Cashman at (800) 872-2054 or (508) 653-6329 or respond by e-mail to [email protected]. Reservations not canceled at least 24 hours in advance must be paid. Members, $28.00; Non-members, $30.00; Retirees, $15.00; Students, $10.00. Anyone who needs handicapped services/transportation, please call a few days in advance so that suitable arrangements can be made.

THE PUBLIC IS INVITED

SUPPORTING DOCUMENTATION: ACTIVITY 8

NESACS FUNDRAISING BOOKLETS

From the Report of the Committee on Corporate Funding

In order to make the fundraising plans as effective as possible, Chairs of committees were asked to write a paragraph and/or provide pictures that best described what their activities and programs entailed. The Fundraising Committee compiled and edited the information into two brochures that were printed in color and bound to better appeal to particular sponsors. One brochure was specifically on the ACS Scholars program and the other on NESACS activities.

Letter to Potential Donors December 6, 2004

Dear «Salutation»:

The Northeastern section’s most recent and continuing activities have included support of our younger chemists and students through exchange visits with the Jungchemikerforum of the German Chemical Society, Project SEED and the ACS Scholars Program. The section also proudly sponsors several nationally recognized ACS awards including: James Flack Norris Awards for Physical Organic Chemistry and for Outstanding Achievement in the Teaching of Chemistry; Gustavus John Esselen Award for Chemistry in the Public Interest; and, the Theodore William Richards medal for Achievement in Chemistry. A further effort to expand the public awareness of chemistry has lead to the establishment of the Phyllis A. Brauner Memorial Lecture during National Chemistry Week. The medicinal chemistry symposium is another specialized activity that the Section has supported for many decades.

Your support is crucial for the continuation and expansion of these activities. Please consider extending your generosity again and, if possible, expanding it. Your corporation’s gift will be acknowledged in the section’s monthly publication, THE NUCLEUS, and at NESACS functions. For gifts of $2,000 or greater you will be listed as a Benefactor while gifts of $1,000 or $500 will be acknowledged as a Corporate Patron or Corporate Sponsor respectively.

Please send your donation to “Northeastern Section ACS”, Attn: Dr. James Piper, Treasurer, 19 Mill Road, Harvard, MA 01451. Please also include your corporate name for our public acknowledgements. The Northeastern Section of the American Chemical Society, Inc. is a 501(c) 3 non-profit corporation with tax ID Number 04-6037800.

Members of our fundraising committee would be happy to make a personal visit to highlight some of our programs if needed.

Kindest regards,

Dorothy J. Phillips, Ph.D. Jean A. Fuller-Stanley, Ph.D. Chair, Fund Raising and Corporate Relations Committee Chair, Northeastern Section

52 Booklet mailed to potential donors in 2004 (cover only included here)

Northeastern Section American Chemical Society

Highlights of Selected 2003 Programs and Activities

“Inspiring Future Scientists”

53 Booklet mailed to potential donors in 2004

ACS Scholars Program in the Northeastern Section

ACS Scholars attend NESACS Meeting February 2004

What is the ACS Scholars Program

® A scholarship programs sponsored by ACS and targeted for underrepresented minorities in sciences

¢ African-American, Hispanic, and American Indian students ò Who have strong academic records and show an interest in and potential for careers in the chemical science; ò Who are undergraduates planning to enter the fields of chemistry, biochemistry, or chemical engineering, or ò Who are seeking a two-year degree in chemical technology

Goal of ACS Scholars Program

® To aid in building an awareness of the value and the rewards associated with careers in science and ® To assist minority students in acquiring the skills and credentials needed for success in these areas

ACS Scholars in NESACS

® NESACS sponsors a scholarship for one student in the program ® Twenty-three Scholars attend colleges that are located within the Northeastern Section ® Northeastern Section builds on the program goals by inviting Scholars to attend monthly meetings and fostering mentoring relationships

55 NESACS Harvard University ACS Scholars

® Sharon O. Doku ® Candice J. Givan ¢ Junior in Chemical ¢ Senior, Chemistry major engineering ® Lauren M. Goins ® Adan Farinas ¢ Senior in Biochemistry ¢ Senior in Biochemistry ® Daniel D. Golab ® Christina Ann Fields ¢ Senior in Chemistry ¢ Junior in Chemistry ® Shirley Lemus Hufstedler ® Roy G. Hughes, Jr. ¢ Freshman in Biochemistry ¢ Junior in Biochemistry

NESACS MIT ACS Scholars

® Silvana R. Arevalo ® Nduka O. Enemchukwu ¢ Freshman, Chemical engineering ¢ Junior, Materials Science & ® Pedro L. Arrechea Engineering ¢ Senior Chemical engineering ® Doris M. Grillo-Gonzalez ® Elisa E. Calimano ¢ Freshman Chemistry ¢ Senior, Chemistry ® Christiana O. Obiaya ® Yamicia D. Connor ¢ Junior, Chemical Engineering ¢ Freshman, Chemical ® Nicholas A. Pearce

Engineering ¢ Freshman, Chemical ® Reuben L. Cummings Engineering ¢ Senior, Chemical Engineering ® Keith G. Reed ¢ Senior, Chemical Engineering

56 NESACS Scholars cont.

MIT cont. Northeastern University ® Silvia C. Robles ® Ryan R. Richardson

¢ Freshman , Chemical ¢ Freshman, Chemistry Engineering ® Jillian A. Smith ¢ Freshman, Chemical Engineering ® Roberto Velazquez ¢ Freshman, Chemistry ® Cherelle R. Walls ¢ Freshman, Chemical Engineering

The Scholars Program has identified 1355 scholarship winners since inception in late 1994 as follows:

771 female 57% 584 male 43% 766 African American 57% 512 Hispanic/Latino 38% 77 Native American 5%

Majors: 469 Chemistry 35% 503 Chemical Engineering 37% 166 Biochemistry 12% 195 Related Majors 14%

57 Graduates - 504 as Follows:

293 female 58%

212 male 42%

285 African American 56%

200 Hispanic/Latino 40%

20 Native American or American Indian 4%

Follow-up (79% or total tracked to date):

213 are in graduate school 53%

189 are currently in the chemical work force 47%

Retention Rate:

Student retention in the ACS Scholars Program 82%

Founding Partner - Donor of $500,000+

PPG Industries Foundation, Inc.

Partners - Donors of $100,000 or more *AstraZeneca Pharmaceuticals Bayer Corporation Camille and Henry Dreyfus Foundation, Inc. DuPont Central Research GlaxoSmithKline Inc. The Procter & Gamble Company Xerox Corporation * Site in the Northeastern Section

58 Contributors

Air Products and Chemicals, Inc. *Genzyme Corporation *Amgen, Inc. Great Lakes Chemical Company BASF Corporation *Rohm and Haas Company *Cambridge Isotope Labs Schering-Plough Foundation Shell Chemical Company The Dow Chemical Corporation Societé de Chimie Industrielle Eastman Chemical Company *Strem Chemicals, Inc. FMC Corporation Tripos, Inc. Ford Motor Company *Wyeth-Ayerst Research Geneva College ACS North Jersey Local Section ACS Central Texas Local Section ACS Philadelphia Local Section ACS New York Local Section *ACS Northeastern Local Section * Offices located in the Northeastern Section

The ACS Scholars Program and Project Seed are 2001 winners of The Presidential Award for Excellence in Science, Mathematics, and Engineering Mentoring.

The ACS Scholars Program is a 1997 winner of the American Society of Association Executives (ASAE) Award of Excellence.

59 SUPPORTING DOCUMENTATION: ACTIVITY 9

ACS SCHOLARS PROGRAM

Please see supporting documentation for Activity 8 for copy of booklet published by NESACS highlighting the ACS Scholars Program.

From the Education Committee Report

ACS SCHOLARS PROGRAM (Morton Hoffman, Chair)

ACS Scholars: 2003-2004 academic year.

HARVARD UNIVERSITY Jessica Bazick Mark Garro Roy Hughes, Jr. Melissa McCreery Durrell Robinson Sharon Doku Chikezie Eseonu Christina Ann Fields

MASSACHUSETTS INSTITUTE OF TECHNOLOGY Silvana Arevalo Nia Beckley Yamicia Connor Jamira Cotton Ruben Cummings Nduka Enemchukwu Ismael Gomez Nicholas Pearce Doris Grillo Gonzalez Aline Thomas Roberto Velazquez Jillian Smith (NESACS ACS Scholar)

NORTHEASTERN UNIVERSITY Mark Michelman Ryan Richardson

TUFTS UNIVERSITY Camille Petersen

These Scholars were contacted by e-mail monthly from September to May, and informed of NESACS activities of interest to undergraduates. In particular, they were invited to attend the monthly meetings of the Section, and to be its guests at the social hours and dinners that preceded the invited speakers. They also were put on the mailing list to receive THE NUCLEUS.

NESACS Commitment to Support ACS Scholars Program

Subj: NESACS ACS Scholars Renewed Contributions Date: 02/13/04 1:40:57 PM Eastern Standard Time From: [email protected] To: [email protected] CC: [email protected], [email protected], [email protected] Sent from the Internet (Details)

Dear Robert Hughes;

60 On behalf of the Northeastern Section (NESACS) I am pleased to inform you that the NESACS Board voted at the February 12th 2004 meeting to extend our financial support to the ACS Scholars Program. Our last financial commitment expired at the end of 2003. The Section wish to renew this commitment to an outstanding program to continue to increase the diversity and vibrancy of Chemistry and the Society. The Northeastern Section will contribute the sum of $2500 each year for four years ( 2004-2007) to the ACS Scholars Program.

NESACS Treasurer, Jim Piper will work with ACS office on the details of the financial transaction.

Best regards

Jean A. Fuller-Stanley Ph.D. Professor and Chair, Chemistry Wellesley College, Wellesley, MA 02481 Phone: 781 283 3224 FAX: 781 283 3642 E-mail: [email protected] NESACS Chair 2004

Invitation to Attend Section Meetings

Greetings. On behalf of the Chair of the Northeastern Section of the American Chemical Society (NESACS), Professor Jean Fuller-Stanley of Wellesley College, I would like to welcome you to the area as ACS Scholars for 2003-04. Some of you have been Scholars over the past few years, and may remember my previous messages to you as Chair (2002) and Immediate Past-Chair (2003) of NESACS. I now serve as the Chair of the College Subcommittee of the NESACS Education Committee (Ruth Tanner, Chair), and will be the liaison between you and our American Chemical Society local section.

I apologize for not getting in touch with you earlier in the academic year, but circumstances conspired to delay this communication. However, it is not too late to invite you to attend the upcoming NESACS meeting and dinner as guests of the Section. The meeting, which will take place on Thursday, February 12, at Boston College, is a joint meeting with the NESACS Younger Chemists Committee (YCC), a group of students, postdoctorates, and young professionals who seek to encourage the study and practice of chemistry. The meeting will feature a YCC symposium in the afternoon on "Careers in Communicating Science," a social hour and dinner, and a talk by Dr. William Carroll, Jr., ACS President- Elect.

61 A flyer (suitable for framing) in rtf format about the meeting is attached. Boston College is conveniently reached via the "T" on the "B" Green Line (Commonwealth Avenue). For travel directions and more information about NESACS, go to ; current (and past) issues of The NUCLEUS, the NESACS monthly newsmagazine, are availabe in pdf format at that site.

I hope you will be able to come to the meeting on February 12, meet some of the younger (and older) chemists of Eastern Massachusetts and New Hampshire, and begin your professional networking. If you intend to come, please contact Marilou Cashman, the NESACS administrator, by telephone at 800-872- 2054 or via e-mail no later than noon on February 5 in order to secure your seat at the dinner.

While you have your calendar open, please note the remaining NESACS meetings of this academic year: March 11, April 15, May 13. I promise to send you invitations to attend in a timely fashion.

Until we meet, I want to wish you good luck with your studies and success in everything chemical.

Morton Hoffman ******************************************************************* Professor Morton Z. Hoffman Tel: 617-353-2494 Department of Chemistry Fax: 617-353-6466 Boston University e-mail: [email protected] 590 Commonwealth Avenue Boston, MA 02215

ACS Scholars Program in the Northeastern Section

ACS Scholars attend NESACS Meeting February 2004

ANNUAL REPORT Northeastern Section, ACS

APPENDIX 2

BUDGETS LONG-RANGE PLAN

http://www.nesacs.org

63 APPENDIX 2 - BUDGETS AND LONG-RANGE PLAN

APPENDIX 2

REPORT OF THE TREASURER - 2004

Page 1 of the financial report reflects the transactions in the operating account of the Section. In addition to the operating account, the Trust Funds operate under the supervision of the Board of Trustees. The operating account generally pays all bills and then requests reimbursement of Trust-related expenses from the Trustees. In 2004, those reimbursements totaled $64,711.09 (line 10). Since the Trust funds are separately maintained, the calculation of the Public Support ratio on page 2 of the Financial Report is incorrect. The correct calculation is on the attachment to the Financial Report.

The market value of the Trust Funds at the end of 2004 was $2,274,891.55, an increase of $193,209.73 from 2003.

A separate set of books is kept for the Nucleus, and these are maintained on an accrual basis. The financial results presented by the Board of Publications differ from those in the Treasurer’s report because the latter is presented on a cash basis.

The Attorney General of the Commonwealth of Massachusetts requires nonprofit organizations to file annual reports. In 2003, organizations with gross revenue exceeding $250,000 were required to submit audited financial statements. The audited statements for 2003 were completed and the report filed in August. For 2004, the requirement for audited financial statements was modified so that $500,000 is the revenue level that triggers the audit requirement. Therefore, in 2004 the Section will need a review rather than an audit.

James U. Piper Treasurer

64 2-A: Budgets

BUDGET 2004

Northeastern Section 01/02/04 draft Budget Proposal 2003 2003 2004 2004 2004 Annual Account # Budget Actual Requests Proposed Proposed From General Offsetting Acct National Allotment 10 26,841.00 26,841.00 29,195.00 Travel Grants 11 12,000.00 13,677.30 12,000.00 Local Dues 12 42,000.00 41,985.97 42,000.00 New-member Commission 13 50.00 45.00 50.00 Contributions 14 8,000.00 11,769.00 22,000.00 9,000.00 Other Program Income 15 2,300.00 2,765.00 8,775.00 Project SEED 16 6,000.00 2,425.00 6,000.00 Continuing Education 17 4,000.00 19,575.00 2,000.00 8,000.00 Dinner Receipts 18 7,000.00 9,529.00 7,000.00 Savings Interest 19 150.00 77.78 100.00 Miscellaneous 20 0.00 3,708.00 Trustees: Cons. Acct. 21 1,000.00 0.00 1,000.00 Perm. Inc. Acct. 22 10,750.00 3,029.00 9,000.00 Norris Inc. Acct. 23 23,000.00 29,524.87 30,100.00 Richards Inc. Acct. 24 8,850.00 16,437.88 14,000.00 Publ. Inc. Acct. 25 13,000.00 4,000.00 8,000.00 Hill Award 26 1,500.00 4,000.00 1,500.00 Esselen Award 27 14,000.00 12,000.00 14,000.00 Levins Award 28 700.00 0.00 700.00 Brauner Lecture 29 2,000.00 NERM 30 0.00 8,800.00 Summer Programs 31 4,500.00 13,036.00 500.00 2,000.00 Advertising 32 46,000.00 49,143.00 50,000.00 50,000.00 INCOME TOTALS 231,641.00 272,368.80 95,845.00 183,075.00 TOTAL 278,920.00 Chair 50 3,315.00 2,791.65 4,100.00 4,100.00 Business Office 51 1,800.00 1,866.04 1,850.00 Treasurer 52 5,522.50 790.46 5,600.00 800.00 4,800.00 22 Archivist 53 100.00 90.46 400.00 400.00 Publication, Web Site 54 5,000.00 0.00 Nucleus 55 64,990.00 66,808.04 69,480.00 11,480.00 58,000.00 see notes Program 56 2,125.00 1,014.21 1,000.00 1,000.00 Ballots 57 1,750.00 1,847.97 1,850.00 Public Relations 58 750.00 593.79 750.00 Prof. Relations 59 850.00 0.00 1,200.00 1,200.00 Education 60 9,712.50 9,922.62 15,000.00 11,825.00 3,175.00 15 Newell Awards 61 700.00 1,029.00 1,000.00 1,000.00 22 Ashdown Awards 62 1,820.00 2,428.52 2,500.00 1,900.00 600.00 15 Continuing Education 63 2,000.00 17,116.54 8,000.00 8,000.00 17 Local Arrangements 64 15,000.00 19,519.01 8,600.00 7,000.00 18 New & 50 Yr members 65 600.00 70.00 Membership Committee 66 1,000.00 423.66 1,000.00 1,000.00 Hill Award 67 1,500.00 4,045.71 1,500.00 26 Norris Award 68 16,000.00 13,945.30 16,000.00 23 Speakers Bureau 69 150.00 32.52 400.00 400.00 23 Summer Scholars 70 13,700.00 15,494.15 13,700.00 13,700.00 23 Project SEED 71 12,000.00 4,811.11 6,000.00 6,000.00 16 Richards Medal 72 0.00 88.50 12,000.00 24 Esselen Award 73 14,000.00 13,119.07 14,000.00 27 Levins Prize 74 700.00 640.00 700.00 28 Sec. School Award 75 2,000.00 2,178.65 2,000.00 24 Aula Laudis 76 550.00 695.17 500.00 500.00 22 Trustees 77 1,000.00 628.89 1,000.00 21

65 Safety Committee 78 0.00 0.00 Chair-elect 79 1,955.00 512.10 2,700.00 2,700.00 Legislative Affairs 80 0.00 0.00 National Chem. Week 81 6,250.00 5,049.90 6,650.00 4,650.00 2,000.00 29 Summer Programs 82 2,000.00 12,715.36 2,000.00 31 ACS Scholars 83 2,700.00 2,500.00 2,500.00 2,700.00 22 Medicinal Group 84 7,500.00 3,430.53 7,500.00 7,500.00 Travel Grants 85 18,000.00 19,759.04 6,000.00 12,000.00 11 Adm. Secretary 86 18,000.00 15,882.26 Inc1 to $27 18,000.00 Miscellaneous 87 0.00 121.00 NERM 88 100.00 0.00 100.00 Younger Chemists Comm 89 4,080.00 3,201.73 9,600.00 4,600.00 5,000.00 15 Jung Chemiker 90 7,000.00 7,754.60 21,000.00 12,000.00 9,000.00 14 EXPENSE TOTALS 246,220.00 252,917.56 108,305.00 183,075.00 TOTAL 291,380.00

BUDGET 2005

Northeastern Section Draft 01/13/05 Budget Proposal 2004 2004 2005 2005 2005 Annual Account # Budget Actual Requests Proposed Proposed From INCOME General Offsetting Acct National Allotment 10 29,195.00 29,195.00 29,859.00 Travel Grants 11 12,000.00 17,044.16 20,000.00 Local Dues 12 42,000.00 53,617.38 60,000.00 New-member Commission 13 50.00 0.00 50.00 Contributions 14 31,000.00 9,971.09 10,000.00 Other Program Income 15 8,775.00 18,557.00 10,575.00 Project SEED 16 6,000.00 0.00 2,850.00 Continuing Education 17 10,000.00 9,825.00 8,000.00 Dinner Receipts 18 7,000.00 9,547.25 7,000.00 Savings Interest 19 100.00 171.64 150.00 Miscellaneous 20 0.00 2,526.23 Trustees: Cons. Acct. 21 1,000.00 1,220.21 1,000.00 Perm. Inc. Acct. 22 9,000.00 14,995.17 8,800.00 Norris Inc. Acct. 23 30,100.00 19,158.89 23,250.00 Richards Inc. Acct. 24 14,000.00 12,565.82 8,850.00 Publ. Inc. Acct. 25 8,000.00 8,000.00 Hill Award 26 1,500.00 1,576.00 1,500.00 Esselen Award 27 14,000.00 15,195.00 14,000.00 Levins Award 28 700.00 0.00 700.00 Brauner Lecture 29 2,000.00 2,000.00 NERM 30 0.00 0.00 Summer Programs 31 2,500.00 2,464.00 500.00 2,000.00 Advertising 32 50,000.00 47,830.50 45,000.00 45,000.00 INCOME TOTALS 278,920.00 265,460.34 100,559.00 163,525.00 TOTAL 264,084.00 EXPENSE Chair 50 4,100.00 3,329.46 6,000.00 6,000.00 Business Office 51 1,850.00 1,102.40 1,350.00 Treasurer 52 5,600.00 11,655.06 5,600.00 800.00 4,800.00 22.00 Archivist 53 400.00 118.84 250.00 250.00 Publication 54 0.00 0.00

66 Nucleus 55 69,480.00 61,840.67 68,239.00 13,239.00 53,000.00 various Program 56 1,000.00 217.54 500.00 500.00 Ballots 57 1,850.00 1,782.30 1,850.00 Public Relations 58 750.00 365.10 1,000.00 Prof. Relations 59 1,200.00 0.00 1,200.00 0.00 Education 60 15,000.00 10,201.12 13,500.00 9,025.00 3,475.00 15.00 Newell Awards 61 1,000.00 1,021.13 1,000.00 1,000.00 22.00 Ashdown Awards 62 2,500.00 1,525.07 2,500.00 1,900.00 600.00 15.00 Continuing Education 63 8,000.00 8,550.34 8,000.00 17.00 Local Arrangements 64 15,600.00 20,425.56 8,600.00 7,000.00 18.00 Membership Committee 65 1,000.00 390.53 600.00 600.00 Hill Award 66 1,500.00 1,922.34 1,500.00 26.00 Norris Award 67 16,000.00 8,417.89 16,000.00 23.00 Speakers Bureau 68 400.00 0.00 400.00 400.00 23.00 Summer Scholars 69 13,700.00 11,313.47 13,700.00 13,700.00 23,24 Project SEED 70 12,000.00 3,873.00 6,188.00 3,350.00 2,850.00 16.00 Richards Medal 71 12,000.00 7,297.67 0.00 24.00 Esselen Award 72 14,000.00 15,042.58 14,000.00 27.00 Levins Prize 73 700.00 623.60 700.00 28.00 Sec. School Award 74 2,000.00 1,791.00 2,000.00 24.00 Aula Laudis 75 500.00 566.36 375.00 500.00 22.00 Trustees 76 1,000.00 625.96 1,000.00 21.00 Chair-elect 77 2,700.00 1,527.76 1,675.00 1,675.00 National Chem. Week 78 6,650.00 6,141.60 6,950.00 4,950.00 2,000.00 29.00 Summer Programs 79 2,000.00 2,146.00 2,000.00 31.00 ACS Scholars 80 2,700.00 2,500.00 2,500.00 2,500.00 22.00 Medicinal Group 81 7,500.00 2,205.89 7,500.00 5,500.00 Travel Grants 82 18,000.00 22,778.88 6,500.00 20,000.00 11.00 Adm. Secretary 83 18,000.00 17,002.75 @28 17,500.00 Miscellaneous 84 0.00 108.12 200.00 NERM 85 100.00 0.00 Younger Chemists Comm 86 9,600.00 9,499.80 12,100.00 4,600.00 6,500.00 15.00 Jung Chemiker 87 21,000.00 24,861.41 12,000.00 12,000.00 EXPENSE TOTALS 291,380.00 262,771.20 101,389.00 163,525.00 TOTAL 264,914.00

67 APPENDIX 2

LONG-RANGE PLAN

Long-Range Planning Meeting June 22, 2004 5:00 p.m. – 7:00 p.m. Science Center – Wellesley College Wellesley, MA

AGENDA

Younger Chemists Committee German Exchange Program Board of Publications Editorial arrangements for The Nucleus Electronic Communications Electronic Voting Fund-Raising Committees Structure and Formation / Dissolution Other items to be added

MINUTES

Long-Range Planning 2004 June 22, 2004

Attending: Jean Fuller-Stanley, Amy Tapper, Mike Strem, Susan Buta, Vince Gale, Joe Bilio, Al Viola, Wally Gleekman, Vivian Walworth, Myke Simon, Dorothy Phillips, Ruth Tanner, Doris Lewis, David Yesair, Jim Piper, Raj(SB) Rayir? Patrick M. Gordon, Michaeline Chen, Liming Shao, M. S. Chorghade, Pam (Patricia) Mabrouk, Arlene Wick Light, Ted Light, Pamela Nagafuji

Fuller-Stanley, chair of NESACS, presiding

Election results announced (note: Patricia Mabrouk, chair-elect, likes to be called Pam). Please refer to e- mail from Marilou Cashman of 06-05-04.

‹ YCC Proposal: See proposal read per Mike Strem’s e-mail of June 16, 2004 (See Below):

68 Dear Members of the NESACS Board:

The YCC/Jungchemiker (JCF) program between NESACS and the German Chemical Society (GDCh) is now four years old. We have sent a group to Germany twice and they have sent a group to Boston twice. We have been invited to Berlin for April 2005, but before accepting, we are requesting formal approval by the NESACS Board for continuation of the program, including the make-up of the NESACS committee to steer the program. We are requesting this approval at the June Board meeting, as delaying it would make our organizing efforts for 2005 very difficult because of the time lines required.

The importance to the scientific education of the students, and the relevance to international networking among chemists argue strongly that the program be continued. The receipt of several Chemluninary Awards by our section because of the program reinforces that argument. Therefore, we are making the following recommendations to the NESACS Board:

1) We request that the Board accept the GDCh-JCF invitation for a group of students and their accompanists from NESACS to travel to Berlin during the week of 3-10 April 2005. Part of the program will be participation in the two day "Euroregionale" which includes students from Germany as well as other European countries.

2) We request the NESACS Chair name the following people, should they agree to serve, to the ad hoc Organizing Committee for the 2005 Exchange: Mike Strem (Chair), Amy Tapper, Ruth Tanner, Morton Hoffman, Aida Herrera, Cassandra Celatka, Lauren Wolf, Tony Fernandez, Sonia Taktak, Ivan Korendovych, and Christian Hackenberger.

3) We request that the Board commit to support the 2005 exchange to a maximum of $12,000. for twelve students plus the NESACS Chair (or designate) and the NESACS-YCC Chair (or designate).

Discussion Q’s (Strem) German Chemical Society wants to continue the program; strongly-invited our YCC group back with no strings or expectations to a reciprocal trip attached for 2006. (Simon) Can we do something with other countries? (Chorghade) Suggests to de-link this program with other international programs and to consider other programs separately (Mabrouk) -ChE society-are we merging? Should they be contacted? Chair-elect: That plan is not going forward, or at least still more to be worked out. (Phillips) How much did YCC raise so far in our fundraising efforts via the Conference? (Treasurer-Piper) $7000 company donations, $6000-career fair, $4000-baseball tickets (Strem) Career fair was helped by presence of the international students. (Tapper) Both students and companies positively received career fair. Chemluminaries were won (and this year nominated) for all four years that YCC has functioned. (?) Who pays what? Why is this year less expensive then last year? (Strem) The host country funds room and board, travelers pay transportation. This year we are travelers. (Viola) How does the treasurer feel about funding this proposal? (Treasurer): If we budget 12K we’ll make it through the year. (Viola) Would like to see the Exchange Committee open up to a broader range of students, accompanying professionals, NESACS Board members, etc. (Tapper) YCC advertises this program in the Nucleus and on YCC’s website. (Mabrouk) suggests improvement in outreach via letters to the dept chairs or students themselves via e- mail. (Lewis) Good motivational tool for joining national and locals ACS. (Tanner) Moves question. (Chorghade) seconds. Approved (Strem) moves proposal

69 (Chorghade) seconds. Approved. The proposal will be funded.

‹ Board of Publications-The Nucleus

Chair recognizes Chorghade for stepping into difficult transition. (Lewis) Board owes great thanks to all involved with making the transition a success. Chair: Vince Gale introduced as advertising editor of the Nucleus. Vivian Walworth--part of Board of Publications (BOP). She and Gale were instrumental in editorial team assemblage.

(Gale) Mark Spitler is managing editor; Nancy Simons is associate editor. Both worked with Patrick at Polaroid. Either one will accept information for the Nucleus. There are other associate editors, but NESACS Board would not have contact with them. (Gleekman) Nancy’s e-mail corrected: [email protected] (Gordon) Arno Heyn is still being consulted. Team is completely comprised of volunteers.

Why Financial overruns? (Chorghade) Printing had extra billing that was not budgeted.

(Tanner) Questions whether editor should be paid. (Piper) Remuneration must be written and approved per by-laws. (Strem) puts forth a motion to pay editors as of July 2004 (Tanner) seconds. (Gordon) requests BOP considers this motion. (Gleekman) Can we substitute that we request BOP to give NESACS Board recommendation about the remuneration (retroactive to July 1) to Nucleus editors by Sept Board meeting? (Treasurer) Careful about recommending over the budget. (Gale) – Arno did work of the 4 people now needed and was excellent. The task is not as huge when divided by four. Please take this under consideration. (Strem) accepts Wally’s modification as substitute motion if retroactive remuneration back to July 1 is part of the substitute motion. (Billo) supports BOP current position of first balancing the budget. He also wants compensation to be appropriate. (Tanner) Who are the other editors mentioned? (Gale) Ao Zhang- (Production end), and yet to be named 4th position part of the editorial crew, four proofreaders, plus other minor editors. (Viola): Nucleus is vital tool; feels volunteer working staff can’t put the time and energy into what the job is really worth. Supports Mike Strem’s initial motion. It’s too risky to wait until Sept. (Gordon) has every confidence in the team. Doesn’t see any indication that a dip in service will occur. Chair requests phone number, etc of editors (Gordon) Will send all info to Marilou Cashman. (Buta) What actually happened to finances of Nucleus--was it resolved? (Chorghade) formatting numbers, equations, and budgets into final copy needed extra help from the printer mostly due to inexperience with the computer programs needed to format the figures. (Walworth)-Arno supported waiting with remuneration at last BOP meeting. (Simon) Was associate editor for many years and supports volunteer editorial board. Remuneration is not the motivator. (Lewis) Requests much closer communications with BOP. Ideal would be a written recommendation plus representation in Sept and following months. (Strem) We have a tradition of paying the editor (or call it an honorarium). He suggests keeping the tradition going.

70 (Buta) Requests safeguards spelled out in case Nucleus deadlines missed or quality suffers. (Gordon) Safeguards already proven during this transition. Chair: two questions for BOP Honorarium amount? To be discussed Who is responsible for deadlines? Managing editor (Tanner) Question called. (Tapper) seconds. Question called

Motion Vote: BOP to provide NESACS board with recommendation for remuneration by Sept. NESACS board meeting: approved, 2 opposed no abstentions. Motion approved.

(Viola) Requests written recommendation from BOP prior to actual NESACS board meeting. Chair asks Gordon to follow up.

‹ Finances

(Mabrouk) Only one SEED student this year so requests $2000 of $6000 budget to support HS teacher. Pam worked with this teacher last year. Became interested in research and requested a research opportunity. (Lewis) Supports proposal and motions that $2000 will be allowed to transfer to HS teacher to support summer research. (Tapper) seconds- Motion approved.

‹ Treasurer Report. Total assets- remarkably stable considering stock market. Treasurer feels we are in reasonable state.

‹ Fundraising Chair: Phillips worked on two booklets. Printing done via Wellesley College Chemistry Dept, to lower cost. Final copy looks great and will be ready next week. (Phillips) The committee put together the booklet. Coming up: Vendor Fair (Sept 9th at Radisson Hotel in Woburn). Anyone can solicit vendors. E-mail Dorothy for details and flyer. July 12 meeting to sort out Sept 9th vendor fair that will be held during the Medicinal Chem. symposium. Professional relations committed to focus on employment service presentations in the afternoon. Chorghade, Wick-Light (interviewing), and Light (outsourcing) are doing presentations.

‹ Chem. Luminaries Chair: 3 nominations. • YCC program • YCC event • Hands on Activities Nat’l Chemistry Week. Poster info will be needed for Nat’l meeting in August. Send photographs to Chair.

‹ NERM 2004: Oct 30-Nov.3 in Rochester, NY Soliciting nominations for NE Regional HS Teacher award- Need nomination for July 1. NERM holding a Chemagination contest (science essay and poster contest) for HS students addressing: “What innovation or breakthrough in the field of chemistry will be important in the lives of teenagers 25 years from now?” Categories include: Biotechnology, Medicine/Healthcare, New Materials, or Transportation / Environ-ment. Contact Chair for details of this program. (Tanner) Please bring this program to the attention to Steve Lantos as chair of HS committee.

71 ‹ Electronic Communications Webmaster. (Chair) We may need a different model in the future. Sam is doing a great job, but he has received a grant and may not be able to spend more time on the site. NJ / NY both employ webmasters for long term. NJ is very different then our site. Our site may need revamping. (Tanner) National recommended our board hire a paid Webmaster. (Gordon): BOP cost/benefit may not be there since there’s not a lot of work to be done to maintain the website at this point. (Strem) Should we put paid advertising on our Website? (Gale) 5% of our NESACS membership goes onto our website. If we get 1000 member hits, we would go for web advertising. We get hits from outside the membership. Gale feels our site is among the best from what he can see. (Simon) –NY does not have a Nucleus or equivalent-maybe their website fills that gap. Chair-We need to be forward-looking. (Gale) agrees because we should always strive for improvement in the future. (Tanner) We should review the design of site with questions such as: Is the site information friendly? Can you immediately find what you need? Does the organization of material need to be looked at? Example: should we have search capabilities on our home page? (Tapper) Job postings may need to be more pronounced. (Chorghade) Novartis specifically asked for that sort of help.

‹ Other (Gleekman) Summerthing III tomorrow- Red Sox game; Summerthing IV- August 6th visit, to Genzyme facility on Soldier’s Field road. 10:00 a.m. with lunch at Old Country Buffet $7.00. Free 2004 entertainment books available if you buy a 2005 book in Sept. $20.

Meeting adjourned.

(Notes taken by Susan Buta)

ANNUAL REPORT Northeastern Section, ACS

APPENDIX 3

MEMBERSHIP SURVEYS NEWSLETTERS

http://www.nesacs.org

73 APPENDIX 3 - MEMBERSHIP SURVEY AND 2003 NEWSLETTER

3-A: No membership survey was conducted in 2004.

3-B: 2004 Newsletter April 2004 issue of The Nucleus uploaded into online report.

Copies of The Nucleus may be viewed in PDF format on the NESACS web site at http://www.nesacs.org

ANNUAL REPORT Northeastern Section, ACS

APPENDIX 4

PUBLIC RELATIONS PLAN TALKS TO PUBLIC

http://www.nesacs.org

75 APPENDIX 4

4-A: Public Relations Plan

The following public relations activities are included in the Public Relations Plan for 2004:

‹ Provide press releases for publication in The Nucleus and area newspapers relating to all meetings of the Section ‹ Make arrangements for a photographer to be present at all meetings of the Section including

• March 2005 Richards Medal Award ° April 2005 Esselen Award ° May 2005 Education Awards ° October 2005 Hill Award & 50-Year Member Certificates ° November 2005 Norris Award

‹ Photographs will also be printed in The Nucleus and posted on our web site.

‹ Arrange for preparation, e-mailing, and posting on web site of flyers describing monthly meetings; e-mail to approximately 200 chemists, colleges, and businesses in the area approximately three weeks prior to each meeting of the Section with follow-up reminder notices approximately one week prior to each meeting.

‹ Arrange for mailing, e-mailing, and posting on web site of information about Section activities relating to high school students and teachers to all high schools in the Northeastern Section's geographical area. Specifically, this includes the following: ° Ashdown and Olympiad Examinations ° Richards Award for Outstanding Secondary School Teaching ° Lyman C. Newell Grants to attend NEACT summer conference ° National Chemistry Week activities ° Connections to Chemistry Program for High School Teachers ° Speakers' Bureau

‹ Arrange for information about Section activities relating to college students to be mailed and e-mailed to all colleges and universities in the Northeastern Section's geographical area and to be posted on the web site. Specifically, this includes the following: ° Norris - Richards Undergraduate Summer Research Scholarships ° Northeast Student Chemistry Research Conference (NSCRC) ° National Chemistry Week activities ° Undergraduate Research Poster Session Call for Papers (ACS) ° Undergraduate Grants-in-Aid to attend 2005 National ACS meeting ° Philip L. Levins Memorial Prize These activities are also posted on the YCC web site

‹ Arrange for information relating to Continuing Education programs offered by the Section to be mailed to ~450 individual chemists and chemical companies, e-mailed to approximately 200 chemists, published in The Nucleus and posted on the web site.

‹ All items mentioned above will be publicized in The Nucleus and posted on the web site.

‹ Press releases relating to Section activities will be written as information is provided and upon request from officers and committee chairs; these will be distributed appropriately via flyers, The Nucleus, area newspapers, Chemical & Engineering News, and area television and radio stations.

76 Press Release of Hill Award Submitted to “Arlington Advocate”

The Northeastern Section of the American Chemical Society (ACS) announces Dr. Donald O. Rickter of Arlington, MA as the 2004 Henry A. Hill Award for distinguished service to the Section and the profession of chemistry. The award was presented to Dr. Rickter at the 854th Meeting of the Northeastern Section, held on October 14th at Wellesley College in Wellesley, MA. Dr Rickter, a 35 year resident of Arlington, becomes the 24th recipient of the award.

Dr. Rickter earned AB and MS degrees from the University of California-Davis and his Ph.D. in organic chemistry from Michigan State University in 1964. Prior to serving as a Research Scientist and Information Manager at Polaroid, Dr. Rickter served in the United States Navy and taught high school and college chemistry. While at Polaroid, Dr. Rickter served as liaison between Polaroid and the Northeastern Section from 1974-1996, as Section Chair and Chair-elect (1998, 1999), Congressional Science Councilor for the 8th District, MA (1974-1998), Co-Chair Professional Relations Committee (1997) and as chair or member of various other boards and committees. In addition to his dedicated service to the Section, Dr. Rickter participated in the planning of the State Capital Days (1998, 2000) and served on the Presidential Task Force for K-12 Education in 2001. He is currently an independent information consultant.

The Henry A. Hill Award was established in 1979 by the friends and colleagues of Dr. Hill in the Northeastern Section. Born in St. Joseph, Missouri, Dr. Hill obtained a bachelors degree from Johnson C. Smith University, at the time a segregated university, and followed in 1942 with a Ph.D. degree in organic chemistry from the Massachusetts Institute of Technology. Dr. Hill overcame prevalent discrimination, and along with several colleagues, founded a consulting firm following graduation. In 1952, Dr. Hill rose to the position of Vice President of National Polychemicals and co-authored several patents. Dr. Hill served as Chair of the Northeastern Section in 1963 and was very active in the National ACS, serving as member and chair of several committees. He also served as a Director of the ACS from 1971 to 1975, when he was elected President-Elect, and became President in 1976. Dr. Hill is especially remembered for drafting the basis of the Professional Employment Guidelines, while serving on the Professional Relations Committee. The first Henry A. Hill award was award posthumously to Dr. Hill in 1980 and accepted on his behalf by his son Anthony C. Hill, a reporter for WGBH.

The Northeastern Section is the local affiliation of the American Chemical Society, serving Eastern Massachusetts and New Hampshire. The Society is a nonprofit organization with a multidisciplinary membership of more than 159,000 chemists and chemical engineers.

Note: Press releases are interspersed throughout Appendix 5 relating to various activities of the Northeastern Section.

77 APPENDIX 4-B: TALKS TO PUBLIC

Date Speaker/Affiliation - Title/Topic Location

8-Jan Dr. Mark Murcko / Vertex Pharmaceuticals Harvard Faculty Club How Do New Technologies Influence the Drug Design Process? 28-Jan Prof. David Liu / Harvard University Boston Colege An Evolution-Based Approach to the Creation & Discovery Of Synthetic Molecules 4-Feb Prof. Vernon Reinhold / University of New Hampshire Northeastern University Chemical & Analytical Strategies for Complete Glycoprotein Characterization 10-Feb Prof. Shana Kelley / Boston Colege Tufts University DNA Damage Promoted by Amino Acids 11-Feb Prof. John Esingmann MIT Synthesis of Novel Toxins that Block DNA Repair & Hijack Transcription Factors: Applications to Cancer Chemotherapy” 24-Feb Prof. Dr. Michael Wolfe / Harvard Medical School Tufts University Biochemistry and Inhibitionof Ei-Secretase 25-Feb Prof. Tom Tullius / Boston University Northeastern University Adding Another Dimension to the Genome: Chemical Maps of DNA Structure 8-Mar Prof. Timothy Jamison / MIT Brandeis University Total Synthesis Using Cascades & Selective Catalytic Multi- Component Coupling Reactions 11-Mar Prof. John Clardy / Harvard Medical School Boston College DNA-Based Approaches to Natural Products 11-Mar Prof. Robert Langer / MIT Tufts University Materials for Drug Delivery and Tissue Engineering 15-Mar Prof. Amy Keating / MIT Biology Department MIT Combinatorial Interactions of the bZIP Transcription Factor Leucine Zippers: Measurements and Predictions 17-Mar Prof. Ashok Cholli / University of Mass. Lowell Northeastern University Biocatalytically Synthesized Opto-electronic Polymers and Nanocomposites 22-Mar Prof. Gregory Fu / MIT Harvard University Palladium-Catalyzed Coupling Reactions 23-Mar Dr. Mukund Chorghade / Pharmachem, Inc. UMass Boston Fascinating Adventures in the Progress of a Drug From Conception to Commercialization 6-Apr Prof. James Hendrickson / Brandeis University UMass Boston Organization of Organic Chemical Knowledge for Automatic Generation of Synthesis Routes: The ‘SynGen’ Program 14-Apr Prof. Barbara A. Seaton / Boston Univ. School of Medicine Brandeis University Structural Basis of Peripheral Membrane Protein Action 14-Apr Young Mi Kim / Swager Group, MIT MIT Synthesis & Applications of Electron Deficient Conjugated Polymers 29-Apr Dr. S. R. Holmes-Farley / Genzyme Corp. UMass Lowell Advances in Polymeric Pharmaceuticals 3-May Prof. Timothy F. Jamison / MIT Harvard University Development and Applications of Cascades and Selective Catalytic Multi-Component Coupling Reactions 6-May Dr. Michael E. Strem / Strem Chemicals, Inc. MIT The Story of Strem Chemicals 17-May Prof. David Liu / Harvard University Harvard University An Evolution-Based Approach to the Creation and Discovery of Synthetic Molecules 27-May Dr. Norton Peet / Aurigene Discovery Technologies Radisson Hotel, Woburn Introduction to MedChem Drug Discovery Symposium 27-May John Tallarico / Harvard Inst. of Chemistry & Cell Biology Radisson Hotel, Woburn Natural-Product-Inspired Compound Libraries – from Synthesis To Screening to ChemBank

9-Sept Norton Peet / Aurigene Discovery Technologies Radisson Hotel, Woburn Introduction to MedChem Symposium – New Uses for Old Drugs 9-Sept Timothy Barberich / Sepracor, Marlborough, MA Radisson Hotel, Woburn Evolution of the Improved Chemical Entity(ICE) Strategy 9-Sept Dr. Mukund Chorghade / NESACS Prof. Relations Committee Radisson Hotel, Woburn Career Services Seminar: Resume Preparation 9-Sept Arlene Wick Light / NESACS Prof. Relations Committee Radisson Hotel, Woburn Career Services Seminar: Interviewing Skills 9-Sept Dr. Truman S. Light / NESACS Prof. Relations Committee Radison Hotel, Woburn Career Services Seminar: Globalization Issues & Chemical Employment 28-Sept Prof. Yoshito Kishi / Harvard University Boston College Organic Chemistry Seminar 13-Oct Prof. Edwin Jahngen / University of Mass. Lowell Burlington (MA) H.S. Connections to Chemistry: Cows Eat Grass; People Eat Pasta 13-Oct Prof. Frank Gorga / Bridgewater State College Burlington (MA) H.S. Connections to Chemistry: Bonding & Molecular Graphics 4-Oct Prof. Timothy Swager / MIT Harvard University PresenterTriptycene: Translation of a Simple Chemical Structure into New Structural and Electronic Materials 12-Oct Prof. Li Deng / Brandeis University Boston College Organic Chemistry Seminar 25-Oct Prof. Susan Lindquist / Whitehead Inst. & Dept of Biology, MIT MIT Biological Seminar Series 26-Oct Prof. Joseph Sadighi / MIT Tufts University Small Molecule Activation and New Bond-Forming Reactions By Low Coordinate Late Transition Metal Complexes 29-Oct Prof. Andrei Tokmakof / MIT Boston College Physical Chemistry Seminar 6-Nov Prof. Tom Tullius / Boston University Boston University Undergraduate Day – Opening Remarks 6-Nov Prof. Morton Hoffman / Boston University Boston University Undergraduate Day – Opening Remarks 6-Nov Jenifer Levine / Boston University – Student Affiliates President Boston University Undergraduate Day – Opening Remarks 6-Nov Prof. Mathew Shair / Harvard University Boston University Keynote:Undergraduate Day – From Biology-Inspired Organic Synthesis to Organic Synthesis for Studying Biology 6-Nov Prof. Mark Grinstaff / Boston University Boston University Undergraduate Day – Synthesis & Applications of Buiodendrimers 6-Nov Dr. Antony Wright / Strem Chemicals, Inc. Boston University Undergraduate Day – Navigating a Chemistry Career to Include Employment within a Commercial Enterprise 6-Nov Prof. Scott Schaus / Boston University Boston University Undergraduate Day – Choosing a Graduate School 6-Nov Dr. Frank Wagner / Strem Chemicals, Inc. Boston University Undergraduate Day – Preparing Your Resume 6-Nov Prof. John Fourkas / Boston College Boston University Undergraduate Day – Making Things with Light 6-Nov Prof. Adam Yeager / Boston University Boston University Undergraduate Day – Development of Chemical Libraries Using Parallel Synthesis 6-Nov Prof. Anthony Fernandez / Merimack College Boston University Undergraduate Day – Resuscitating a Shallow-Breathing Student Affiliates Chapter 10-Nov Prof. John Esigman / MIT UMass Boston Synthesis of Anticancer Agents that Hijack Transcription Factors and Disrupt DNA Repair 17-Nov Prof. Morton Hoffman / Boston University UMass Dartmouth Interesting Insights into Modern Developments in Chemical Education

79 3-Dec Dr. Randy Holmes-Farley / Genzyme Corporation UMass Lowell. Sukant Tripathy Annual Memorial Symposium Speaker 9-Dec Norton Peet / Aurigene Discovery Technologies Radisson Hotel, Woburn Introduction to MedChem Symposium – Kinase Targets 13-Dec Dr. Jack Szostak / Mass. General Hospital & Harvard Med. School Harvard University The Transition from Chemical Evolution to Darwinian Evolution 15-Dec Prof. Catherine C. Neto / University of Mass. Dartmouth UMass Dartmouth The Phytochemicals behind the Potential Health Benefits of Cranberries

APPENDIX 4-C

Press Release of Hill Award Submitted to “Arlington Advocate” Additional press releases are interspersed throughout Appendix 5 as Items from The Nucleus.

ANNUAL REPORT Northeastern Section, ACS

APPENDIX 5

AS NEEDED BY SECTION NESACS REPORTS

http://www.nesacs.org

APPENDIX 5 - AS NEEDED BY SECTION

TABLE OF CONTENTS

Officers, Councilors, Directors, and Committee Chairs 2004 ...... 83

Calendar of Activities 2004...... 89

Reports: Archivist...... 92 Awards Committee...... 93 Awards Presented by the Northeastern Section ...... 102 Brauner, Phyllis A. - Memorial Lecture...... 103 Constitution & Bylaws Committee ...... 106 Continuing Education Committee ...... 106 Corporate Funding...... 110 Education Committee ...... 115 Education Committee / High School Subcommittee ...... 123 Esselen Award Committee...... 137 Government Relations Committee...... 145 Local Arrangements Committee...... 146 Long-Range Planning ...... 146 Medicinal Chemistry Group ...... 151 Membership Committee ...... 159 National Chemistry Week Committee...... 162 NERM 2004 ...... 164 Nominating Committee...... 165 Norris Award Committee ...... 166 Professional Relations Committee ...... 173 Program Committee / Chair-Elect...... 174 Public Relations Committee ...... 175 Public Service Committee / Elementary Education Task Force ...... 177 Publications, Board of...... 178 Richards Medal Committee...... 184 Speakers' Bureau ...... 187 Summerthing 2004 ...... 188 Treasurer ...... 191 Trustees, Board of ...... 191

APPENDIX 5-A: Highlights of 2004 Section Meetings in Pictures ...... 194

APPENDIX 5-B: Programs and Publications

Northeast Student Research Conference...... 204 Connections to Chemistry...... 219 Undergraduate Research Symposium at Bridgewater State College...... 231 Employment Guide for ACS Members...... 236

82 NORTHEASTERN SECTION OFFICERS / COUNCILORS / CHAIRS -- 2004

Chair Dr. Jean A. Fuller-Stanley Chemistry Dept., Wellesley College, Wellesley, MA 02481 (P) 781-283-3224 (F) 781-283-3642 [email protected]

Chair-elect Dr. Amy Tapper Peptimmune, 64 Sidney St., Suite 380, Cambridge, MA 02139 (P) 617-715-8005 [email protected]

Past-Chair Dr. John L. Neumeyer 1 Holiday Road, Wayland, MA 01778 (P) 617-855-3388 (F) 617-855-3585 [email protected]

Secretary Dr. Michael Singer Sigma-RBI, 1 Strathmore Road, Natick, MA 01760 (P) 508-651-8151 x291 (F) 508-655-1359 [email protected]

Treasurer Dr. James U. Piper 19 Mill Road, Harvard, MA 01451 (P) 978-456-8622 (F) 978-456-8949 [email protected]

Auditor Dr. Anthony L. Rosner 1443 Beacon Street, Apt. No. 201, Brookline, MA 02446 (P) 703-276-7455 (F) 703-276-8178 [email protected]

Trustee Dr. Esther A. H. Hopkins 1550 Worcester Road, Unit 309, Framingham, MA 01702 (P) 508-872-8148 [email protected]

Trustee Mr. Joseph A. Lima 11 Morningside Avenue, Natick, MA 01760 (P) 617-244-5764 (F) 617-254-2713 [email protected]

Trustee Dr. Michael E. Strem Strem Chemicals, Inc., 7 Mulliken Way, Newburyport, MA 01950 (P) 978-462-3191 (F) 978-465-3104 [email protected]

Councilor Miss Mary Burgess 63 Weld Hill Street, Boston, MA 02130-4150 (P) 617-522-9165 [email protected]

Councilor Mrs. Michaeline Chen 529 Grove Street, Needham, MA 02492 (P) 781-235-5201 [email protected]

Councilor Dr. Catherine Costello B. U. School of Medicine, 715 Albany Street R-806, Boston, MA 02118-2394 (P) 617-638-6490 (F) 617-638-6491 [email protected]

Councilor Dr. Thomas Gilbert Chemistry Department, Northeastern University, Boston, MA 02115 (P) 617-373-4505 (F) 617-373-8795 [email protected]

Councilor Dr. Michael J. Hearn Chemistry Department, Wellesley College, Wellesley, MA 02481 (P) 781-283-3127 (F) 781-283-3642 [email protected]

Councilor Dr. Morton Z. Hoffman Chemistry Department, Boston University, Boston, MA 02215-2507 (P) 617-353-2494 (F) 617-353-6466 [email protected]

Councilor Dr. Patricia A. Hogan 806 Bay Road, Stoughton, MA 02072-3957 (H) 781-344-4636 [email protected]

Councilor Dr. Doris I. Lewis 236 Lexington Street, Newton, MA 02466 (P) 617-573-8546 (F) 617-573-8668 [email protected]

Councilor Mrs. Arlene W. Light 85C Seminary Avenue, Lasell Village, Apt. 239, Auburndale, MA 02466-0260 (P) 617-244-5764 [email protected]

Councilor Dr. Truman S. Light 85C Seminary Avenue, Lasell Village, Apt. 239, Auburndale, MA 02466-0260 (P) 617-244-5764 [email protected]

Councilor Dr. Patricia A. Mabrouk Department of Chemistry, Northeastern University, Boston, MA 02115 (P) 617-373-2845 (F) 617-373-8795 [email protected]

Councilor Dr. Julia Miwa Chemistry Dept., Wellesley College, Wellesley, MA 02481-8203 (P) 781-283-3128 (F) 781-283-3642

Councilor Dr. Dorothy J. Phillips 10 Lamplight Circle, Natick, MA 01760 (P) 508-482-2860 (F) 508-482-3100 [email protected]

84 Councilor Dr. Amy Tapper Peptimmune, 64 Sidney St., Suite 380, Cambridge, MA 02139 (P) 617-715-8005 [email protected]

Alternate Councilor Dr. Mukund Chorghade 14 Carlson Circle, Natick, MA 01760 (P) t08-651-7809 (F) 508-651-7921 [email protected]

Alternate Councilor Dr. Timothy B. Frigo Advanced Magnetics, Inc., 61 Mooney Street, Cambridge, MA 02138 (P) 617-497-2070 (F) 617-547-2445 [email protected]

Alternate Councilor Dr. Wallace J. Gleekman 35 Rangeley Road, West Newton, MA 02465 (P) 617-527-1192 [email protected]

Alternate Councilor Dr. Patrick M. Gordon 1 Brae Circle, Woburn, MA 01801-2222 (P) 781-932-0169 [email protected]

Alternate Councilor Dr. Lowell H. Hall Chem. Dept., Eastern Nazarene College, Quincy, MA 02170 (P) 617-773-6350 (F) 617-773-4839 [email protected]

Alternate Councilor Dr. Howard R. Mayne Department of Chemistry, University of New Hampshire, Durham, NH 03824-3598 (P) 603-862-2358 (F) 603-862-2529 [email protected]

Alternate Councilor Dr. Donald O. Rickter 88 Hemlock Street, Arlington, MA 02474 (P) 781-643-7575 [email protected]

Alternate Councilor Dr. Lawrence T. Scott Chemistry Department, Boston College, Chestnut Hill, MA 02467 (P) 617-552-8024 [email protected]

Alternate Councilor Dr. Michael Singer Sigma-RBI, 1 Strathmore Road, Natick, MA 01760 (P) 508-651-8151 x291 (F) 508-655-1359 [email protected]

Alternate Councilor Dr. J. Donald Smith Dept. of Chem., Univ. of Mass. Dartmouth, No. Dartmouth, MA 02747 (P) 508-999-8231 (F) 508-999-9167 [email protected]

85 Alternate Councilor Dr. Alfred Viola 14 Glover Road, Wayland, MA 01778 (P) 508-358-7222 [email protected]

Alternate Councilor Dr. David Warr Dept. of Natural Sciences, Bristol Comm. College, Fall River, MA 02720-7307 (P) 508-678-2811 (F) 508-295-5222 [email protected]

Alternate Councilor Dr. Derk A. Wierda 22 Orchard Drive, Durham, NH 03824 (P) 603641-7148 [email protected]

Alternate Councilor Mrs. Barbara Wood P. O. Box 198, Melvin Village, NH 03850 (H) 603-544-3351 [email protected]

Director-at-Large Dr. Carmela Amato-Wierda Chem. Dept., Univ. of New Hampshire, Durham, NH 03824-3598 (P) 608-862-2526 [email protected]

Director-at-Large Susan M. Chiri-Buta 3 Knox St., #2, Boston, MA 02116 (P) 617-504-4791 [email protected]

Director-at-Large Dr. Ernest V. Groman 80 Columbia Street., Brookline, MA 02446 (P) 617-738-8501 [email protected]

Director-at-Large Dr. Sarah Iacobucci Chem. Dept., Tufts University, 62 Talbot Ave., Medford, MA 02155 (P) 978-453-5047 [email protected]

Director-at-Large Stephen Lantos 22 McTernan Street, Cambridge, MA 02139 (P) 617-491-3637 (F) 617-730-2635 [email protected]

Director-at-Large Dr. Gary R. Weisman Dept. of Chemistry, University of New Hampshire, Durham, NH 03824 (P) 603-862-2304 [email protected]

Archivist Dr. Myron S. Simon 20 Somerset Road, West Newton, MA 02465-2722 (P) 617-332-5273 [email protected]

Awards Chair Dr. Michael J. Dube Nye, Inc., P. O. Box 8927, New Bedford, MA 02742-8927 (P) 508-996-6721 (F) 508-997-5285 [email protected]

Board of Pubs. Chair Mrs. Vivian K.Walworth 215 Valley Road, Concord, MA 01742-4924 (P) 978-369-3735 [email protected]

Budget Chair Dr. James U. Piper 19 Mill Road, Harvard, MA 01451 (P) 978-456-8622 (F) 978-456-8949 [email protected]

Chem Hlth/Sfty Chair Ms. Mary Ann Solstad 16 Pequot Road, Marblehead, MA 01945 (P) 781-631-4748 (F) 781-631-1832 [email protected]

Chem. Ed. Chair Dr. Ruth Tanner Department of Chemistry, University of Massachusetts Lowell, Lowell, MA 01854 (P) 978-934-3662 (F) 978-934-2013 [email protected]

Const./Bylaws Chair Dr. Catherine Costello B. U. School of Medicine, 715 Albany Street R-806, Boston, MA 02118-2394 (P) 617-638-6490 (F) 617-638-6491 [email protected]

Continuing Ed. Chair Dr. Alfred Viola 14 Glover Road, Wayland, MA 01778 (P) 508-358-7222 [email protected]

Corporate Funding Dr. Dorothy J. Phillips 10 Lamplight Circle, Natick, MA 01760 (P) 508-482-2860 (F) 508-482-3100 [email protected]

Esselen Chair Dr. E. Joseph Billo Chemistry Dept., Boston College, Chestnut Hill, MA 02467 (P) 617-552-3619 (F) 617-552-2705 [email protected]

Local Arrangements Miss Mary Burgess 63 Weld Hill Street, Boston, MA 02130-4150 (P) 617-522-9165 [email protected]

Med. Chem. Rep. Dr. S. B. Rajur 5 Keystone Way, Andover, MA 01810 (P) 978-764-7068 [email protected]

87 Membership Chair Mrs. Michaeline Chen 529 Grove Street, Needham, MA 02492 (P) 781-235-5201 [email protected]

NCW Chair Dr. Christine Jaworek-Lopes Emmanuel College, 400 The Fenway, Boston, MA 02115 (P) 617-264-7614 [email protected]

NERM Chair Dr. Morton Z. Hoffman Chemistry Department, Boston University, Boston, MA 02215-2507 (P) 617-353-2494 (F) 617-353-6466 [email protected]

Nominations Chair Dr. John L. Neumeyer 1 Holiday Road, Wayland, MA 01778 (P) 617-855-3388 (F) 617-855-3585 [email protected]

Norris Award Chair Dr. Frederick D. Greene 25 Canterbury Road, Winchester, MA 01890-3812 (P) 617-253-1840 [email protected]

Nucleus / Editor Dr. Mark Spitler 71 Villa Street, So. Waltham, MA 02453-1543 (P) 781-376-9911 [email protected]

Prof. Relations/ Dr. Truman S. Light and Mrs. Arlene W. Light Career Services 85C Seminary Avenue, Lasell Village, Apt. 239, Auburndale, MA 02466-0260 (P) 617-244-5764 [email protected] [email protected]

Program Chair Dr. Amy Tapper Peptimmune, 64 Sidney St., Suite 380, Cambridge, MA 02139 (P) 617-715-8005 [email protected]

Project SEED Chair Dr. Patricia A. Mabrouk Department of Chemistry, Northeastern University, Boston, MA 02115 (P) 617-373-2845 (F) 617-373-8795 [email protected]

Pub. Relations Chair Dr. Christopher Doona U.S.Army Natick, SBCCOM, Natick, MA 01760 (P) 508-233-5083 [email protected]

Public Service Chair Dr. Mukund S. Chorghade 14 Carlson Circle, Natick, MA 01760 (P) 508-651-7809 (F) 508-651-7920 [email protected]

88 Public Service/ Dr. James A. Golen Elem. Ed. Task Force Dept. of Chemistry, University of Mass. Dartmouth, No. Dartmouth, MA 02747 (W) 508-999-8245 (F) 508-999-8901 [email protected]

Richards Medal Chair Dr. Patricia A. Mabrouk Department of Chemistry, Northeastern University, Boston, MA 02115 (P) 617-373-2845 (F) 617-373-8795 [email protected]

Senior Chemists Chair Mr. Charles J. Bardsley 61 Harrison Avenue, Braintree, MA 02184-4911 (P) 781-843-6604 [email protected]

Webmaster Dr. Samuel Kounaves Chem. Dept., Tufts University, Medford, MA 02155 (P) 617-627-3124 [email protected]

YCC Chair Ms. Lauren Wolf Chem. Dept., Boston University, Boston, MA 02215 (P) 617-353-3072 (F) 617-353-6466 [email protected]

NESACS CALENDAR OF ACTIVITIES - 2004

Date Activity

January 2004 Call for Nominations: Philip L. Levins Memorial Prize (Graduate Student) January 2004 Call for Nominations: Aula Laudis Society (Secondary Teachers) January 8 Monthly Meeting - Harvard Faculty Club Joint meeting with Organizational Meeting of the Boston Area Group for Informatics and Modeling (BAGIM) Dr. Mark Murcko, Vertex Pharmaceuticals, Cambridge, MA Topic: How Do New Technologies Influence the Drug Design Process February 2004 Speakers’ Bureau – Call for Speakers to be listed in Speakers’ Bureau February 2004 Call for Applications: Norris-Richards Research Scholars (Undergraduate Students) February 2004 Employment Guide for Members published in The Nucleus February 12 Monthly Meeting - Joint Meeting with YCC - Boston College, Chestnut Hill, MA Dr. William Carroll, Jr., ACS President-elect Topics: “The Public Perception of Chemistry,” “Pre-College Education and Educators,” and “The Changing Chemistry Enterprise in the U. S.” February 12 YCC Symposium – Careers in Communicating Science – Conte Forum / Boston College Speakers: Prof. B. D. Colen, M. I. T. Prof. A. L. Utz, Tufts University Dr. A. Dichner, C.O.O., BioPro, Inc. March 2004 Call for Papers: Northeast Student Chemistry Research Conference (Graduate & Undergraduate Students) March 11 Monthly Meeting – Harvard Faculty Club Richards Medal Award Prof. John Ross – Prof. emeritus, Stanford University Topic: Biochemical Reaction Mechanisms: Determination and Synthesis

89 April 15 Monthly Meeting - Harvard University Gustavus John Esselen Award Dr. James E. Jorgensen, University of North Carolina at Chapel Hil Topic: “The Magic of Capillaries in Chemical Separations and Analysis” Wk. of Apr. 18 4th Annual NESACS-NSYC/GDCh-JCF Exchange Program German students hosted in Boston by YCC and NESACS April 23 Student Chemistry Carer Fair – Holiday In, Brookline, MA Workshops on resumé-writing and interviewing skils Job Fair with representatives of chemical companies April 24 Northeast Student Chemistry Research Conference - Boston University May 2004 Call for Nominations: Henry A. Hill Award (Service to Northeastern Section) May 9 Summerthing I - Fenway Park, Boston Boston Red Sox & Kansas City Royals Baseball Game May 10-11 ACS Short Course - Northeastern University Experimental Design for Productivity and Quality in R&D Stanley N. Deming / University of Houston May 13 Monthly Meetng / Education Awards - Northeastern University Dr. Guy Koji Nakanishi, Columbia University Topic: “Biorganic Studies of Natural Products” Presentation of Awards: Philip L. Levins Memorial Prize Norris/Richards Undergraduate Research Fellowships Undergraduate Grants-in-Aid Project SEED Certificates Richards Secondary Teaching Awards Aula Laudis Society - Induction of Members Ashdown Examination Prizes Simmons College Prize Phyllis A. Brauner Memorial Book Award May 27 Summerthing II - Fenway Park, Boston Boston Red Sox & Oakland Athletics Baseball Game June 2004 Lyman C. Newell Grants Awarded Grants to attend New England Association of Chemistry Teachers Summer Conference June 17 Andrew H. Weinberg Memorial Lecture – Dana Farber Cancer Institute David A. Kesler, M.D., J.D. – University of California at San Francisco Topic: The FDA Drug Approval Process June 23 Summerthing III - Fenway Park, Boston Boston Red Sox & Minnesota Twins Baseball Game Aug 2-5 NEACT Summer Conference / Brown University, Providence, RI Newell Grants awarded to four high school teachers to attend NEACT Conference August 6 Summerthing IV Tour of Genzyme Corporation facilities / Lunch at Watertown Mall September 2004 Call for Nominations: Gustavus J. Esselen Award (Chemistry in the Public Interest) September 2004 Call for Applications: Grants-in-Aid (Undergraduate Students) - National Meeting / San Diego September 2004 Pre-Announcement - YCC-GHCh/JCF Exchange Trip to Germany Announcement of trip to Germany to take place April 3-10, 2005 September 9 Monthly Meeting – Joint meeting with Medicinal Chemistry Group Medicinal Chemistry Group Symposium – Radisson Hotel, Woburn, MA Topic: New Uses for Old Drugs Norton Peet, Aurigene Discovery Technologies, Lexington, MA Topic: Introductory Remarks George Muller, Celgene Corporation, Warren, NJ Topic: The Two Faces of Thalidomide Timothy Barberich, Sepracor, Marlborough, MA Topic: Evolution of the Improved Chemical Entity (ICE) Strategy Prof. Camille Wermuth, Université Louis Pasteur, Strasbourg, France

90 Topic: New Leads from Old Drugs: The SOSA Approach September 9 NESACS Vendor Fair – Radisson Hotel, Woburn, MA September 9 Career Services Employment Seminar Resume Preparation – Mukund Chorghade Interviewing Skills – Arlene Wick Light Globalization Issues & Chemical Employment – Truman S. Light October 2004 Call for Papers: Undergraduate Research Poster Session - National Meeting / San Diego October 2004 Annual Nucleus Buyers Guide published October 13 Connections to Chemistry - High School Teacher Workshop - Burlington (MA) High School Workshop Sessions: A: Turn Them into Writers B: The Real CSI Lab C: Cows Eat Grass; People Eat Pasta D: Bonding and Molecular Graphics Program Speaker: Mark Klempner, MD National Center for Emerging Infectious Diseases and Biodefense & Boston University Topic: Vampires, Rockets and the Hot Zone – Confronting Emerging Infectious Diseases October 14 Monthly Meeting - Wellesley College Club, Wellesley, MA Henry A. Hill Award for Outstanding Service to the Northeastern Section to Donald O. Rickter 50-Year Members of ACS presented certificates of recognition Francis Coppa, Esq. Topic: Better Chemistry, Better Mousetrap! Patents and What They Can Do for You Oct-Nov 2004 National Chemistry Week Activities October 17 Phyllis A. Brauner Memorial Lecture / Wellesley College Science Center Dr. Jerry Bell, ACS & Dr. Jim Golen, University of Massachusetts Dartmouth Theme: Health and Wellness! Hands-on Activities related to Health and Wellness November 6 Thirteenth Annual Northeast Regional Undergraduate Day / Boston University Keynote Speaker: Prof. Matthew D. Shair, Harvard University Topic: From Biology-Inspired Organic Synthesis to Organic Synthesis for Studying Biology Research Talks & Seminar Prof. Mark Grinstaff, Boston University Synthesis and Applications of Biodendrimers Dr. Antony Wright, Strem Chemicals Navigating a Chemistry Career to Include Employment within a Commercial Enterprise Prof. Alex Golger, Boston University Demonstrations in Chemistry to Fascinate Kids Prof. Scott Schaus, Boston University Choosing a Graduate School Dr. Frank Wagner, Strem Chemicals Preparing Your Resume Graduate School and Industry Fair Prof. John Fourkas, Boston College Making Things with Light Dr. Adam Yeager, Boston University Development of Chemical Libraries Using Parallel Synthesis Prof. Anthony Fernandez, Merrimack College Resuscitating a Shallow-Breathing Student Affiliates Chapter November 6 Third Annual Undergraduate Environmental Research Symposium / Bridgewater State College Keynote Speaker: Dr. Bill Freedman, Dalhousie University, Halifax, Nova Scotia Environmental Impacts of Forest Harvest Practices in Canada November 11 Monthly Meeting / M.I.T., Cambridge, MA James Flack Norris Award Dinner & Program Dr. Richard N. Zare, Stanford University Topic: Chemical Fizzics: Seeing Chemistry in Action

91 October 28-29 ACS Short Course / Northeastern University Analytical Biotechnology – Characterization of Protein Therapeutic Drug Products David Car, Trainer and Consultant December 2004 Call for Nominations - Norris Award (Outstanding Achievement in the Teaching of Chemistry) December 2004 Call for Nominations - Levins Memorial Prize (Graduate Student) December 2004 Call for Speakers – NESACS Speakers’ Bureau December 9 Monthly Meeting / Radisson Hotel, Woburn Joint Meeting with the Medicinal Chemistry Group Symposium: Kinase Targets Norton Peet, North Andover, MA Topic: Introductory Remarks David Dudley, Pfizer Global Research & Development, Ann Arbor, MI Topic: Development of non-ATP Competitive MEK Inhibitors Michael Block, AstraZeneca R&D, Boston, MA Topic: The Discovery of the EGFR Inhibitor IressaTM (ZD1836, gefitinib) Prabha Ibrahim, Plexxicon, Inc., Berkeley, CA Topic: Discovery of Kinase Inhibitors through a Novel Aproach – “Scafold-Based Drug Discovery” TM

REPORT OF THE ARCHIVIST - 2004 Myron S. Simon, Ph.D., Archivist

The Archives continue to be located in the basement of the library building at Regis College, Weston, MA.

The normal activities, collecting the reports of the meetings of the Board of Directors and the Board of Publications, the Treasurer’s reports, meeting flyers, photographs, etc. have continued. The continuing gathering of reports and other conservable materials has led to the need for an additional filing cabinet, and one has been purchased and put into operation.

Considerable material has been deposited by Richard Handrick for examination for keeping in the archives. Handrick was closely involved with the Trustees during many years, and he compiled valuable reports which will be added to the relatively meager material already in the Trustees’ folder.

Several of the Chemluminary Awards which this Section has won in the national competitions of the American Chemical Society have been temporarily located for display in the James Flack Norris Room at Northeastern University.

Respectfully submitted, M. S. Simon

92 REPORT OF THE AWARDS COMMITTEE - 2004 Michael J. Dube, Chair

The responsibility of the Awards Committee for NESACS includes the presentation of two awards issued by the Section. These awards include the Henry A. Hill Award and the Phillip Levins Prize.

The former is awarded to a member of the Northeastern Section for meritorious service. This year the award was presented to Dr. Donald O. Rickter. This award was presented at the October local section meeting.

The Levins Prize is awarded to a graduate student demonstrating superior achievement. This year, the award was given to Kai Zhang from the University of Massachusetts Dartmouth, under the direction of Prof. Yuegang Zuo.

Respectfully submitted, Michael J. Dube, Ph.D. Chair, NESACS Awards Committee

94 Hill Award Program 2004

NORTHEASTERN SECTION

of the

AMERICAN CHEMICAL SOCIETY

Presentation of the

Twenty-fourth

HENRY A. HILL MEMORIAL AWARD for Outstanding Contribution to the Northeastern Section

Donald O. Rickter

Thursday, October 14 Two thousand four Wellesley College Club Wellesley, Massachusetts

PROGRAM

Jean A. Fuller-Stanley Chair, Northeastern Section, presiding

RECOGNITION OF FIFTY-YEAR MEMBERS

Presentation of Certificates Jean A. Fuller-Stanley

THE HENRY A. HILL AWARD

Henry A. Hill Award Anthony Cromwell Hill

Introduction of Award Recipient Michael J. Hearn

Presentation of the Award Michael J. Hearn

Acceptance Donald O. Rickter

ADDRESS

"Build Me a Better Mousetrap! Patents and What They Can Do For You"

Francis Coppa, Esq. Patent Attorney

96 PRIOR RECIPIENTS of the HENRY A. HILL MEMORIAL AWARD for Outstanding Contribution to the Northeastern Section

Henry A. Hill (posthumously)...... 1980 Edward R. Atkinson ...... 1981 Robert D. Eddy ...... 1982 Arnet L. Powell (posthumously) ...... 1983 G. Richard Handrick...... 1984 Janet S. Perkins...... 1984 Phyllis A. Brauner...... 1985 Arno H. A. Heyn ...... 1986 Sr. Magdalen Julie Wallace (posthumously) ...... 1987 Esther A. H. Hopkins...... 1988 Wallace J. Gleekman ...... 1989 James U. Piper...... 1990 Valerie Wilcox...... 1991 Ernest I. Becker...... 1992 Arlene W. Light...... 1993 Truman S. Light...... 1993 William O. Foye ...... 1994 Michael E. Strem...... 1995 Alfred Viola ...... 1996 Mary T. Burgess...... 1997 Michaeline F. Chen...... 1997 David M. Howell ...... 1997 John L. Neumeyer...... 1998 Morton Z. Hoffman ...... 1999 Catherine E. Costello...... 2000 Myron S. Simon...... 2001 Michael J. Hearn...... 2002 Doris I. Lewis...... 2003

97 This month we are honoring the memory of Henry A. Hill by giving awards in his name to one of our Section members for meritorious service to the Northeastern Section.

Who was Henry A. Hill?

Henry Hill was Chairman of our Section in 1963. He was very active in the national ACS, and served as a member of and chairman of several of its committees. His service on the Professional Relations Committee was especially notable where he drafted the Professional Employment Guidelines. He was Director of the ACS in 1971-1975, was elected President-elect and became President in 1976.

Born in St. Joseph, Missouri, he obtained a bachelor's degree from Johnson C. Smith University, then a segregated university for "colored" students as they were then called. Because of his excellent record, he was accepted at M.I.T., studying organic chemistry. He obtained the Ph.D. in 1942 working under Professor Robert C. Hockett with the highest grades of the graduate students in his class. While at M.I.T., he became acquainted with Professor James Flack Norris of whom he said:

He was the first big man I met who was more interested in my ability to learn chemistry than in the identity of my grandparents.

Not being able to obtain a position in industry because of prevailing discrimination, he and a few colleagues established a small consulting business. In 1946 he joined Dewey & Almy Co. as Research Supervisor, and in 1952 he became Vice President of National Polychemicals which was active in polymer chemistry. He obtained patents for blowing agents.

In 1961 he established his own research and consulting business, Riverside Laboratories, to be able to pursue his research interests and to allow him to participate in ACS activities.

After his untimely death in 1979, friends and colleagues in the Northeastern Section established the Henry A. Hill Award for Outstanding Service to the Northeastern Section. The first award was made posthumously to Henry A. Hill in 1980; his son, Anthony C. Hill, then a reporter for WGBH, accepted the award. Since then, twenty-four members of this Section have been thus honored and thereby honored the memory of Henry A. Hill. From an appreciation of Henry A. Hill delivered by Arno Heyn at the 1991 Hill Award meeting and based on notes of the late Larry Powell.

98 Honored Members

AMERICAN CHEMICAL SOCIETY

Members - Fifty Years

Jaspard Harvey Atkins Richard Stephen Auda Glenn Allen Berchtold John M. Bradley John Joseph Cawley Gerald Dudek Erivan Hagopian Raymond Bush Hanselman Robert Sehon Holdsworth Raymond Joseph Jasinski Muriel W. Kanter Edmund Charles Knapp David Markham Lemal Dolores Lopiekes Haig Markarian Ronald McRae Milburn Ben Fee Moy K. V. Nahabedian Harry George Pars David Lloyd Petterson Donald Rivin Ian Douglas Robinson Henry Sarafian Donald Storer Smith Samuel Cooper Smith John Roman Stemniski Arnold Bernard Tarr Vernon Harold Ure Alfred N. Wohlwend John Edward Zarembo

99 50-Year Member Invitation to Hill Award Dinner

N ORTHEASTERN SECTION AMERICAN CHEMICAL SOCIETY

JEAN FULLER-STANLEY SECTION OFFICE CHEMISTRY DEPT., 23 COTTAGE STREET WELLESLEY COLLEGE NATICK, MA 01760 106 CENTRAL STREET PHONE OR FAX: (508) 653-6329 WELLESLEY, MA 02481 MA & NH ONLY: (800) 872-2054 E-MAIL: [email protected] E-MAIL: [email protected]

August 7, 2004

SAVE THE DATE - (OCTOBER 14)

«Line_1» «Line_2» «Line_3» «Line_4» «Line_5»

«Salutation»

Congratulations on your fifty years of membership in the American Chemical Society. I would like to take this opportunity to commend you on your longevity and continued association with chemistry. As they say, “Old chemists never die; they just reach equilibrium." This is a very important milestone and we of the Northeastern Section would like to celebrate with you.

At the October meeting of the Northeastern Section, in addition to presenting the Hill Award, we will be honoring our fifty-year members. I hope that you (and your spouse) will be able to attend as guests of the Section so that we can congratulate you personally. We are also interested in learning about your career in chemistry. If you would like to do so, we would appreciate receiving a brief biographical sketch that can be added to the archives of the Northeastern Section. It can be sent to the Section office at the address or e-mail shown in the letterhead.

You should already have received a 50-year member lapel pin and a 50-year membership card that entitles you to free registration at ACS National and regional meetings. These were sent to you in March, 2004. If you have not received these, please let me know.

The meeting is on Thursday evening, October 14 at the Wellesley College Club in Wellesley, MA. Additional information and further details of the program and speakers for the evening will appear in the October issue of The Nucleus. Please contact Marilou Cashman in the Section office by October 7 to make your dinner reservations. She may be reached by phone or fax at (800) 872-2054 or by e-mail at [email protected].

Again, my congratulations and thanks for your many years of service.

Sincerely,

Jean A Fuller-Stanley, Chair Northeastern Section, ACS

100 October Meeting Northeastern Section The 853rd Meeting American Chemical Society of the Northeastern Section of the American Chemical Society

Francis Coppa, Esq. Patent Attorney

Build Me a Better Mousetrap!

Patents and What They Can Do For You

Thursday, October 14, 2004 Wellesley College - Wellesley, MA in the Wellesley College Club

5:30 p.m. Social Hour 6:30 p.m. Dinner 50-Year Members to be Honored 7:45 p.m. Evening Meeting: Presiding: Dr Jean A. Fuller-Stanley, Chair, Northeastern Section, ACS Presentation of the Henry A. Hill Award Speaker: Francis Coppa, Esq.

Entrée Choices: Chicken -- Fish -- Vegetarian Please indicate meal choice when making dinner reservations

Dinner reservations should be made no later than noon on Thursday, October 7, 2004. Please send e-mail to [email protected] or call or fax Marilou Cashman at (800) 872-2054 (voice or fax). Reservations not canceled at least 24 hours in advance must be paid.

PRICES: Members: $28.00; Non-Members: $30.00; Retirees: $18.00, Students: $10.00. Pay at the door by cash or check; no credit cards and no purchase orders.

Directions - FREE PARKING ON CAMPUS - Additional information at: http://www.wellesley.edu *Wellesley College Club is the last building on the right entering the campus from Route 135 or the first building on the left entering from Route 16 From the West: Take the Massachusetts Turnpike to Exit 14 (Weston). Go south on Interstate 95 (Route 128) for 1/2 mile to Route 16, Exit 21B. Follow Route 16 West for 2.9 miles to a stoplight (5-way intersection) in the town of Wellesley; go straight on Route 135 (West). At the third traffic light take a left into the main entrance of the College. Follow signs for admission parking. *OPTIONAL: Take Route 16 or Route 135 heading west to Wellesley; campus is located between these two routes. From the East: Take the Massachusetts Turnpike to Exit 16 (West Newton). Follow Route 16 West for 4.7 miles, using directions above. From the North : Take Interstate 95 (Route 128) South to Exit 21B (Route 16 West). Follow Route 16 West for 2.9 miles, using directions above. From the South: Take Interstate 95 (Route 128) North to Exit 21B (Route 16 West). Follow Route 16 West for 2.9 miles, using directions above.

THE PUBLIC IS INVITED

101 AWARDS PRESENTED BY THE NORTHEASTERN SECTION, ACS

James Flack Norris Award Martin Saunders Yale University in Physical Organic Chemistry (presented at ACS National Meeting)

Gustavus John Esselen Award James W. Jorgenson University of North Carolina. for Chemistry in the Public Interest at Chapel Hill

James Flack Norris Award Richard N. Zare Stanford University for Outstanding Achievement in the Teaching of Chemistry

Henry A. Hill Award Donald O. Rickter Polaroid Corp. (retired) for Outstanding Service to the Northeastern Section, ACS

Theodore William Richards Award Valerie J. Lechtanski Hopkinton High School for Excellence in Teaching Gary Liptak Laconia High School, NH

Induction into the Aula Laudis Society W. Cary Kilner Somerset High School, NH John Mauch Braintree High School Marianne McChesney Newton North High School Coretta Tam Newton Country Day School

Lyman C. Newell Grants Linda Ryan Shrewsbury, MA to secondary teachers to Douglas Baker Center Barnstead, NH attend the NEACT Summer Conference Cheryl Nowak Rockland, MA Pamela Bergquist Somerville, MA

Philip L. Levins Memorial Prize Kai Zhang University of Mass. Dartmouth

Norris-Richards Undergraduate Summer Christopher D. Gilmore Boston College Research Scholarships Yehuda Edo Paz Harvard University Cara B. Patten Stonehill College Sarah J. Fischer University of Mass. Lowell

Undergraduate Grants-in-Aid Certificates Elisa Miller Boston University Karen DeBalsi Bridgewater State College Claudia Moura Merrimack College Renato Bauer Stonehill College Shaina Byrne Stonehill College

Dr. Phyllis A. Brauner Memorial Book Award Elisa Miller Boston University

Project SEED Certificates Jie Wen Fang with Northeastern Univ. Mentor Ting Fen Zeng with Northeastern Univ. Mentor

Ashdown Examination Awards: First Place / Simmons College Prize Clara Blättler Brookline High School Second Place Tzyy-Nong Liou Brookline High School Third Place T. Y. Albert Chen Lexington High School Fourth Place Sunny Lou Wayland High School Fifth Place Joshua Kaitz Framingham High School Sixth Place Song Wang Acton-Boxborough High School

102 Seventh Place (tie) Andrew Shu Andover High School Seventh Place (tie) Vladimir N. Mirkin Brookline High School

Honorable Mention - 1st-year Students Elizabeth R. Jerison Belmont High School Michael W. Kaye Wayland High School Alexander Kazberouk Acton-Boxborough High School Lynette Lee Phillips Andover Academy Brian Liu Phillips Andover Academy Ivan Tan Lexington High School

Honorable Mention - 2nd-year Students James Boumil Phillips Andover Academy Eric Frackleton Framingham High School Dan Fromson Phillips Andover Academy Chris Gentile Masconomet High School Jeffrey Grover Framingham High School Adam E. Sandel Brookline High School Jarrod Shaheen Masconomet High School Caroleen J. Verly Wayland High School Joshua M. Weiner Andover High School Kathleen T. Xie Belmont High School

REPORT OF THE PHYLLIS A. BRAUNER MEMORIAL LECTURE COMMITTEE - 2004 Doris I. Lewis, Chair

Members of the Phyllis A. Brauner Memorial Lecture Committee in 2004 were:

Inka Allen Michaelene Chen Chris Jaworek-Lopez Katherine O’Sullivan Steven Allen Dudley Hershbach Ann Jenkins Bassam Shakhashiri Catherine Brauner Arno Heyn Doris I. Lewis Carolyn Spodick Susan Brauner Esther A. H. Hopkins Julianna Lovell Valerie Wilcox

103

Brauner Fund Report – 2004 (Submitted by NESACS treasurer Jim Piper)

Respectfully submitted, Doris I. Lewis, Chair

104 NORTHEASTERN SECTION AMERICAN CHEMICAL SOCIETY

PHYLLIS A. BRAUNER MEMORIAL LECTURE COMMITTEE

DR. DORIS I. LEWIS PHONE: (617) 573-8546 SUFFOLK UNIVERSITY FAX: (617) 573-8668 41 TEMPLE STREET [email protected] BOSTON, MA 02114

October 6, 2004

Dear Friend of the Phyllis A. Brauner Lecture,

Sincerely yours,

Doris I. Lewis, Chair Phyllis A. Brauner Memorial Lecture Committee [email protected] 617-573-8546

Phyllis A. Brauner Memorial Lecture Committee Inka Allen Michaelene Chen Sarah Iacobucci Katherine O’Sullivan Steven Allen Dudley Herschbach Ann Jenkins Bassam Shakhashiri Catherine Brauner Arno Heyn Doris I. Lewis Carolyn Spodick Susan Brauner Esther A. H. Hopkins Julianna Lovell Valerie Wilcox

105

REPORT OF THE COMMITTEE ON AMENDMENTS TO THE CONSTITUTION AND BYLAWS - 2004 Catherine E. Costello, Chair

The committee was composed of the following members:

Catherine Costello, Chair Arno Heyn† Truman Light Esther Hopkins Myron Simon

The Board of Directors of the Northeastern Section is presently considering the modification of the Constitution and Bylaws of the Section to introduce an award in honor of Phyllis Brauner, a former Section chair who contributed significantly to the success of the Section over many years. A draft of the proposed change was sent to the national C&B committee in late 2001 to solicit their opinion on the wording of the changes prior to presentation of the matter to the Section as a whole for formal approval. The report from this committee was received in September 2004 and was presented to the Board. A final decision on the wording should be made shortly. No other C&B changes initiated by the Section are under discussion at the present time. Changes recommended at the national level to allow for electronic balloting will be implemented when this change is made.

Catherine E. Costello Chair, NESACS C&B Committee

Contact person: Prof. Catherine E. Costello Mass Spectrometry Resource Boston University School of Medicine phone: 617-638-6490 715 Albany Street, R-806 fax: 617-638-6491 Boston, MA 02118-2526 e-mail: [email protected]

†died in December 2004

COMMITTEE ON CONTINUING EDUCATION 2004 Annual Narrative Report Northeastern Section

Following the tradition of recent years, the Committee scheduled two events in 2004. Both were held at Northeastern University, which kindly made the required facilities available at no charge to the Section. Since 1993, when we learned that National ACS had decided to make ACS Short Courses available to local sections at tuition fees greatly reduced from the normal fee structure, which is currently in excess of $1000, this Committee has sponsored Short Courses under this aegis. Since our original offering in the Fall of 1993 proved to be a highly successful event, the Committee has continued to bring such courses to the Northeastern Section.

106

1) In the Spring of 2004 the Committee sponsored the two-day ACS Short Course: Experimental Design for Productivity and Quality in R&D Monday, May 10, 2004: 8:00 a.m. – 5:00 p.m. and Tuesday, May 11, 2004: 8:30 a.m. - 5:00 p.m. Paid registration: 7. Total attendees: 11. 7 ACS Members @ $500 2 Unemployed ACS Member no charge 2 Lecturer’s Assistants (Northeastern University Seniors) no charge (In addition, 1 registrant was assessed the late-registration fee of $75) Instructor: Dr. Stanley N. Deming (Professor Emeritus of Analytical Chemistry, University of Houston)

2) In the Fall the Committee sponsored the two-day ACS Short Course: Analytical Biotechnology – Characterization of Protein Therapeutic Drug Products Thursday, Oct. 28, 2004: 8:00 a.m. - 5:00 p.m. and Friday, Oct. 29, 2004: 8:30 a.m. - 5:00 p.m. Paid registration: 10. Total attendees: 14 9 ACS Members @ $500 1 Non-ACS Member @ $600 1 Unemployed ACS Member no charge 3 Lecturer’s assistants (Northeastern University Grad Students) no charge (In addition, 5 registrants were assessed the late-registration fee of $95) Instructor: Dr. David Carr

In accord with National ACS policy, unemployed and retired ACS members were offered admission without charge on a space- available basis.

The above fee schedule included an increment of $50 above the charges set by National ACS, calculated to offset Committee expenses on the basis of the minimum number of 10 registrants required for presentation of the course. The Section also keeps the incremental fees charged to Non-ACS members and to late registrants.

Although the number of registrants for the Spring presentation was below the minimum normally required, the lecturer was local and the absence of hotel and travel expenses permitted the offering to proceed.

These courses have normally been advertised in The Nucleus in the two issues preceding the scheduled event (copies attached). Also, posters were mailed to ca 550 employers of chemists on the list maintained by the Northeastern Section, notices of the Short Courses were posted on the Section’s web site and were also sent to about 75 e-mail addresses maintained by the Section Office. Unfortunately, because of changes in the Editorship of The Nucleus as well as in the composition of the Board of Publications the announcement intended for the October issue of The Nucleus was inadvertently omitted. The Committee believes that this omission resulted in the relatively low enrollment in a course which was expected to be very popular in this area.

Despite the low enrollments in both of these courses, there was still a modest surplus of funds generated for the Section, which will be utilized to support other Section activities.

E. Joseph Billo Vishnu C. Solan James Hall Alfred Viola, Chair Mary Mahaney

107

Experimental Design for Productivity and Quality in R&D

This Short Course is designed for chemical scientists, engineers, R&D managers, and others who need to learn proven methods for designing quality into products and processes. The course assumes no previous knowledge of statistics and is aimed at both beginning and experienced R&D workers. Participants should bring a hand-held calculator to the course.

PLACE: Dodge Hall, Northeastern University, 360 Huntington Ave., Boston, MA

DATES and TIME: Monday, May 10, 2004; 8:00 a.m. – 5:00 p.m. Room 450B and Tuesday, May 11, 2004; 8:30 a.m. – 5:00 p.m. Room 450C

PROGRAM AGENDA - Topics will be selected from the following: Linear Models The Rosetta Stone of Statistics Fractional Factorial Designs The importance of n, p, and f Basic Design Concepts Blocking Choice of Model Looking for Lack of Fit Various Design Possibilities Matrix Least Squares Solutions Looking for Pure Error Mixture Designs Regression Analysis Calibration Multiple Response Estimated Responses Coding Analysis of Variance (ANOVA) Residuals Orthogonal Designs Correlation Coefficient Replication and Pure Error Classical Data Analysis F-Test for Regression and for Lack of Fit Sums of Squares Factorial-Type Designs Confidence Intervals and Bands Degrees of Freedom Yates’ Algorithm Comparing Different Designs

INSTRUCTOR: Stanley N. Deming, Professor Emeritus of Analytical Chemistry at the University of Houston and the President of Statistical Designs. Dr. Deming is the author or co-author of more than 90 publications in the areas of analytical chemistry and related disciplines, including the Elsevier text Experimental Design: A Chemometric Approach, 2nd edition (1992).

PRE-REGISTRATION REQUIRED – Registration Fees: ACS Members if received before April 26…..…… $500.00; after April 26 ……$575.00 Non-ACS Members if received before April 26 ..…$600.00; after April 26 ……$675.00 There will be a limited number of scholarships for unemployed ACS Members on a space-available basis. Parking Fee: about $14.00/day University cafeterias will be available for lunches.

For further information contact: Prof. Alfred Viola at (617) 373 2809 ______

Short Course Registration Form: Experimental Design for Productivity and Quality in R&D, May 10–11, 2004

Name: ______Business Affiliation: ______

Mailing ______Telephone: ______Address (circle: Home or Work) ______E-mail: ______

Mail with remittance to: Prof. Alfred Viola, Chair . NESACS Committee on Cont. Ed. (Please make checks payable to NESACS Department of Chemistry Sorry, we cannot accept credit cards or Northeastern University purchase orders.) Boston, MA 02115

108

ACS SHORT COURSE Designed to improve the skills and marketability of practicing B.S., M.S., and Ph.D. chemists. The NESACS Committee on Continuing Education is pleased to sponsor this new National ACS Two-Day Short Course, at a registration fee less than half of that charged at National ACS Meetings. Analytical Biotechnology - Characterization of Protein Therapeutic Drug Products This Short Course is designed to familiarize chemists and other life science professionals with the techniques and requirements of protein therapeutic analyses. In particular, scientists experienced with traditional small molecule drugs who want to become better grounded in the analysis of protein therapeutics will benefit from this course. DATES and TIME: Thursday, Oct. 28, 2004; 8:00 a.m. – 5:00 p.m. and Friday, Oct. 29, 2004; 8:30 a.m. – 5:00 p.m. PLACE: Room 340 Egan Building, Northeastern University, 360 Huntington Ave., Boston, MA KEY TOPICS TO BE DISCUSSED: The basics of protein therapeutics; Molecular properties of proteins therapeutics which require characterization and/or analysis; Fundamental principles and operating parameters of reversed-phase HPLC, capillary electrophoresis and mass spectrometry used in the characterization and analysis of protein therapeutics; Determination of degradation in protein therapeutics; Characterization and measurement of glycosylation; Pegylation in protein therapeutics and its effect on protein analysis. PROGRAM AGENDA: Introduction to Protein Therapeutics Review of protein chemistry. Protein modifications and degradations: Deamination; Oxidation; Glycosylation; Pegylation. Reversed-Phase HPLC and its role in Protein Therapeutic Analysis Typical operating conditions; Best column characteristics; Optimum mobile phase conditions; Effects of gradients and temperature on peptide separations. Protein therapeutic analysis: Use of reversed-phase HPLC in characterization and analysis of protein therapeutics for degradation products, disulfide bonds, glycosylation and other modifications. Capillary Electrophoresis Mobility, migration and electroosmotic flow; Temperature effects; Operating conditions for proteins and peptides. Modes of operation: Capillary zone; Isoelectric focus; Replaceable gel capillary electrophoresis. Use in analysis of protein therapeutics; Capillary electrophoresis in the analysis of antibody therapeutics. The Rapidly Developing Field of Protein and Peptide Analysis by Mass Spectrometry Ionization sources such as electrospray and matrix-assisted laser desorption (MALDI); Typical mass analyzers; Application of mass spectrometry in the characterization and analysis of proteins, including its role in the analysis of glycosation; LC/MS in protein analysis; Optimum operating conditions. INSTRUCTOR: David Carr is a consultant and trainer in HPLC, electrophoresis, and mass spectrometry of proteins and peptides. He has over thirty years of experience working with the chemical, pharmaceutical, and biotechnology industries. He is the author of the popular monograph, The Handbook of Analysis and Purification of Proteins and Peptides by Reversed-Phase HPLC. PRE-REGISTRATION REQUIRED – Registration Fees: ACS Members if received before Oct. 14…..…… $500.00; after Oct. 14 ……$595.00 Non-ACS Members if received before Oct. 14..… $600.00; after Oct. 14 ……$695.00 There will be a limited number of scholarships for unemployed ACS Members on a space-available basis. Parking Fee: about $14.00/day University cafeterias will be available for lunches. For further information contact: Prof. Alfred Viola at (617) 373 2809 Registration form for Short Course: Analytical Biotech. - Characterization of Protein Therapeutic Drug Products, Oct. 28-29, 2004 Name: ______Business Affiliation: ______Mailing Address ______Telephone:______(circle: Home or Work) ______E-mail: ______Mail with remittance to: Prof. Alfred Viola, Chair Please make checks payable to NESACS NESACS Committee on Cont. Ed. (Sorry, we cannot accept credit cards or Department of Chemistry purchase orders.) Northeastern University Boston, MA 02115

109

REPORT OF THE COMMITTEE ON CORPORATE FUNDING - 2004 Dorothy J. Phillips, Chair

Fundraising Committee Strategies and Results for 2004

The proposed budget for the 2004 projected a shortfall of $30,000. A fundraising committee was organized and charged with reducing the shortfall for the year. Different and more targeted fundraising strategies became the focus in order to raise more than in 2003 which was $5600.

The NESACS Board identified the following programs as fundraising targets: ° YCC-German Students Exchange- $21,000 $9,000 not in budget $12,000 in budget ° Project SEED $6000 ° National Chemistry Week $5000 ° Medicinal Chemistry Group Symposium $7500 yearly ° ACS scholar $2500 ° Education Committee Activities--May meeting ° Professional Relations Career Fair-Workshops Total budget amount for these programs was $33,000.

The Fundraising Committee also organized the first vendor fair sponsored by NESACS, The fair was held with the Medicinal Chemistry Symposium on September 9, 2004. The announcement flyer is attached. Fourteen companies participated with revenue of $5600.

The annual solicitation letter was sent out to area businesses in November 2004. The direct solicitation by members of the Fundraising Committee using the brochures and the letter resulted in raising $3850 from corporate contributions. An additional $7071 was contributed directly to the YCC-German Exchange program; the German students traveled to NESAC in 2004.

The Younger Chemists Committee sponsored a career fair that resulted in an additional $5978.00 for their programs. The NESACS nights at the Red Sox games that are coordinated by Wallace Gleekman continue to be a source of funds for NESACS programs with a 2004 net of $2972.00.

The results for the year are summarized in the attached table and total $29,478. The goal of raising $30,000 in 2004 was achieved. The Fund-raising Committee thanks the YCC for their success in getting support for their programs; Lauren Wolf, YCC Chair and Amy Tapper, NESACS Chair-Elect led this effort.

The Fund-raising Committee appreciates the support of all NESAC members.

Fundraising committee for 2004: ° Dorothy J. Phillips Committee Chair ° Mukund Chorghade ° Doris Lewis ° John Neumeyer ° Lauren Wolf- YCC representative ° David Yesair ° Tim Frigo ° Jean Fuller-Stanley, 2004 NESACS Chair, ex-officio

110

Contributions 14 Corporate Gifts for German Exch Pfizer 500.00 Genzyme 1,800.00 Strem 4,771.09 7,071.09 Corporate Gifts, General Phasex 1,000.00 Millipore Foundation 1,000.00 Zone Enterprises 1,500.00 Millennium Pharm 350.00 3,850.00 10,921.09 Program Fees 15 Ashdown 530.00 Connections to Chemistry 2,160.00 Career Fair Booths Strem 500.00 Wyeth 500.00 PharmEco 500.00 Novartis 500.00 Bayer 500.00 KForce 500.00 Englehard 500.00 Amgen 500.00 Degussa 478.00 Cubist 500.00 Astrazeneca 500.00 Immunogen 500.00 5,978.00 Vendor Fair Phasex 400.00 ER Labs 400.00 US Filter 400.00 Chemsilico 400.00 KForce 400.00 Biotage 400.00 Strem 400.00 Waters 400.00 Wilmark 400.00 Toxicon 400.00 Dionex 400.00 ESA 400.00 Mass. College of Pharm 400.00 Transform Pharm 400.00 5,600.00 Research Conference 435.00 Red Sox tickets 2,972.00 Symphony tickets 882.00 18,557.00

111

NORTHEASTERN SECTION AMERICAN CHEMICAL SOCIETY

ADMINISTRATIVE SECRETARY PHONE OR FAX 23 COTTAGE STREET (508) 653-6329 NATICK, MA 01760 MA AND NH ONLY E-MAIL: [email protected] (800) 872-2054

November 16, 2004

Mr. Barry Singlais Alfa Aesar 30 Bond Street Ward Hill, MA 01835-8042

Dear Mr. Singlais:

The Northeastern Section of the American Chemical Society (NESACS) would like to ask you for your company’s support of its 2004-05 programs. Our section is one of the five largest in the Society; over the last three years the National office has commended us for providing a high level of service to our members and the community at large. With your help and partnership NESACS can continue to maintain that high level of activity. The Northeastern section’s most recent and continuing activities have included support of our younger chemists and students through exchange visits with the Jungchemikerforum of the German Chemical Society, Project SEED and the ACS Scholars Program. The section also proudly sponsors several nationally recognized ACS awards including: James Flack Norris Awards for Physical Organic Chemistry and for Outstanding Achievement in the Teaching of Chemistry; Gustavus John Esselen Award for Chemistry in the Public Interest; and, the Theodore William Richards medal for Achievement in Chemistry. A further effort to expand the public awareness of chemistry has lead to the establishment of the Phyllis A. Brauner Memorial Lecture during National Chemistry Week. The medicinal chemistry symposium is another specialized activity that the Section has supported for many decades. Your support is crucial for the continuation and expansion of these activities. Please consider extending your generosity again and, if possible, expanding it. Your corporation’s gift will be acknowledged in the section’s monthly publication, THE NUCLEUS, and at NESACS functions. For gifts of $2,000 or greater you will be listed as a Benefactor while gifts of $1,000 or $500 will be acknowledged as a Corporate Patron or Corporate Sponsor respectively.

Dorothy J. Phillips, Ph.D. Jean A. Fuller-Stanley, Ph.D. Chair, Fund Raising and Corporate Relations Committee Chair, Northeastern Section

112

Northeastern Section American Chemical Society Vendor Fair

Exhibit at the Medicinal Chemistry Symposium And Career Workshop Network with >100 Qualified Prospects

Thursday, September 9, 2004 3-7 PM Radisson Hotel 15 Middlesex Canal Woburn MA

Three well-known speakers address “ New Uses for Old Drugs”

Professor, Camille G. Wermuth Faculte de Pharmacie, Universite Louis Pasteur, France

Dr. George W. Muller Sr. Director, Chemistry, Celgene Corporation

Mr. Timothy J. Barberich Chairman and CEO, Sepracor

Career Workshop for Mid-Career Chemists 2:30 PM

Cost: $400 per 6 foot table (address checks and mail to NESACS} Contact: Marilou Cashman, NESACS Office 23 Cottage St. Natick, MA 01760 1-800-872-2054 [email protected]

Booklets mailed to potential donors in 2004 – PLEASE SEE APPENDIX 1 FOR A COPY OF THE BOOKLET

113

Corporate Patrons

AstraZeneca R & D Boston Genzyme Drug Discovery & Development Phasex Corporation Strem Chemicals, Inc. Zone Enterprises

Corporate Sponsors

Aerodyne Research, Inc. Cambridge Isotope Labs New England BioLabs, Inc. Pfizer Sigma-RBI

Donors

Consulting Resources Corporation Houghton Chemical Corp. Organix, Inc

114

EDUCATION COMMITTEE Submitted by Ruth Tanner, Chair 2004 Report

Education Committee Members

Ruth E. Tanner, Chair College Stephen Lantos High School Subcommittee Chair Anthony Fernandez Student Affiliates Morton Hoffman ACS Scholars

The Education Committee continued to take an activist position with regard to the organizing of events, the creation of awards, and the recognition of students and faculty in the colleges, universities, and high schools of the Section. Through announcements at the monthly meetings of the Section in The Nucleus, and via mailings, information was provided to the membership in order to foster a greater interest in chemical education and to develop a responsible professional outlook toward chemistry among young scientists.

Morton Hoffman, who is a member of the Education Committee, was elected in 2003 as Chair-Elect (2004) and Chair (2005) of the Division of Chemical Education (CHED), and serves as a member of the CHED Program Committee, Chair of the CHED Regional Meetings Committee, and a member of the CHED International Activities Committee. He is a member of SOCED, and served as a member of the Organizing Committee and a panel moderator of the SOCED Invitational Conference on Exploring the Molecular Vision. He served as a member of the organizing committee of the ACS Invitational Conference on Chemistry Research and Education in the Middle East, and as a member of the Editorial Review Panel for the general chemistry textbook project of the ACS Education Division.

James Flack Norris/Theodore William Richards Undergraduate Summer Research Scholarships. (Edwin Jahngen, University of Massachusetts Lowell, Chair).

The 2004 scholarships were awarded to: Cara Pattern, Stonehill College, The Effect of mut-2 on Recombination Frequency in Caenorhabditits elegans; Dr. Craig Almeida, Advisor

Sarah Fischer, University of Massachusetts Lowell, The Scope and Limitations of the Reaction of Potassium Hydride with Thiones; Dr. Edwin Jahngen, Advisor

Yehuda Edo Paz, Harvard College, Determination of the Structural Basis for HIV-1 integrase Substrate Recognition; Prof. Gregory Verdine, Advisor

Christopher Gilmore, Boston College, The Synthesis of 4(R)-Hydroxy-L-Proline-Glycine Alkene Isosteres; Prof. Scott Miller, Advisor

115

Award winners were required to submit a report of their summer projects by November 2004 for publication in The Nucleus. They are also required to participate in the Northeast Student Chemistry Research Conference (NSCRC) in April 2005.

The competition was publicized through The Nucleus, the NESACS web site, and mailings of applications and descriptive material to the chairs of the Departments of Chemistry, Biochemistry, and Chemical Engineering at colleges and universities in the Section. Applications included student transcripts, descriptions of the proposed research, and two letters of recommendation. The awards enabled the students to spend the summer of 2004 engaged in research at their home institutions.

Thirteenth Annual Northeast Regional Undergraduate Day (Coordinated by Matthew Vigneau, Kevin Burgoyn and Morton Hoffman and Hosted by Chemia, SAACS at Boston University)

Choosing a Graduate School (Prof. Scott Schaus, Boston University) Demonstrations in Chemistry to Fascinate Children (Prof. Alex Golger, Boston University) Resumé Review (Dr. Frank Wagner, Strem Chemicals) Reviving a Shallow-Breathing SA Chapter (Prof. Anthony Fernandez, Merrimack College) Making Things with Light (Prof. John Fourkas, Boston College) Navigating a Chemistry Career to Include Employment within a Commercial Enterprise (Dr. Anthony Wright, Strem Chemicals) Synthesis and Applications of Biodendrimers (Prof. Mark Grinstaff, Boston University) Development of Chemical Libraries Using Parallel Synthesis (Dr. Adam Yeager, Boston University)

The Third Undergraduate Environmental Research Symposium. Sponsored by the Education Committee of the Northeastern Section ACS et al., Bridgewater State College

116

was provided by the Bridgewater State College Adrian Tinsley Program for Undergraduate Research and by the NCUR/Lancy Initiative, a program that provides resources to undergraduates who show promise of exceptional achievement.

The Northeast Student Chemistry Research Conference (VI). Sponsored by the Education Committee of the Northeastern Section ACS and the Younger Chemists Committee of the Northeastern Section

Held at Boston University on April 24, 2004, the sixth annual Research Conference brought together undergraduates, graduate students and post-doctoral fellows from the northeastern region of the country for the purpose of celebrating their accomplishments in research, and for providing a forum for the sharing of ideas and scientific understanding. In addition, this year included German students from the on-going exchange between the Jungchemikerforum (JCF) of the Gesellschaft Deutscher Chemiker (GdCh) and the Younger Chemists and undergraduate students of NESACS. Welcoming remarks were given by Dr. Charles Casey, National ACS President 2004; the keynote address, New Fluoerscent Sensors to Study Biochemical Zinc and Nitric Oxide and to Monitor Mercury in the Environment, was given by Dr. Stephen Lippard of MIT.

In addition to the research poster presentations, there were 6 student presentations--3 undergraduate student speakers and 3 graduate student speakers. The presenting students and their institutions were: Filiz Aslan, Boston University: Engineering Reduced-Size Streptavidin Mutants Sebastian Fritzsche, University of Leipzig: Early-Late Heterobimetallic Salen Complexes as Catalysts for Selective Epoxidation Elisa Miller, Boston University: Chemical Dynamics of High Energy Molecules Pasha Mirazimi, Boston College: Development of Models for the Synamics of Oligomeric DNA through Solid State Nanopore Channels:Prospects for Ultrarapid DNA Sequencing Mingfend Yang, Clark University: Mapping Early Steps of Amyloid Formation with Computational Approaches Christian Ducho, University of Hamburg: CycloSal Pronucleotides – Chemical Trojan Horses with Antiviral Activity

A presentation of the Phyllis Brauner Undergraduate Book Award was made to Elisa Miller from Boston University for her research paper given above.

Grants -in -Aid to Undergraduates (Subcommittee: Ruth Tanner, Martin Isaks)

The Education Committee awards Grants-in-Aid of $250 each to undergraduates at colleges and universities within the Northeastern Section to enable them to attend the national spring meeting of the ACS to present a paper at the Undergraduate Research Poster Session in the Division of Chemical Education. The Education Committee awarded Grants-in-Aid to six undergraduates to enable them to attend the 229th ACS National Meeting in San Diego, California to present a paper at the Undergraduate Research Poster Session in the Division of Chemical Education on Monday, March 14, 2005. Matching funds have been committed by the institutions to support the students’ travel. The recipients are also required to participate in the Northeast Student Chemistry Research Conference (NSCRC) in April 2005.

The awardees, their research supervisors, and the titles of the papers are as follows:

Marcy Keddy, Simmons College (Prof. Richard Gurney) Sustainable Approach to Conducting Polymers Using Electrophilic Carbohydrate Reagents

Alison Erbeck, Bridgewater State College, (Prof. Edward Brush) Synthesis of S-Glutathionyl-3-Bromooxindole Acetic Acid as a Potential Trojan Horse Inhibitor of Glyoxalase II

117

Ellen Sletten, Stonehill College (Prof. Louis Liotta) Stereospecific Synthesis of Polyhydroxylated Pyrrolizidines from Commercially Available Sugars

Yehuda Edo Paz, Harvard College (Prof. Gregory Verdine) Determination of the Structural Basis for HIV-1 Integrase Substrate Recognition

Ryan Smith, Stonehill College (Prof. Leon Tilley) Isotope Effects in Solvolysis of alpha-Trifluoromethyl Gamma- Silyl Systems

Sarah Fischer, University of Massachusetts Lowell (Prof. Edwin Jahngen) The Scope and Limitations of the Reaction of Potassium Hydride with Thiones

Applications for the travel stipend are accepted from students majoring in chemistry, biochemistry, chemical engineering, or molecular biology majors who are in good standing with at least junior status, and are currently engaged in undergraduate research.

CONNECTIONS TO CHEMISTRY (Ruth Tanner, Chair)

Ruth Tanner, Chair, Education Committee, NESACS; University of Massachusetts Lowell Morton Hoffman, Chair-Elect, Division of Chemical Education, ACS: Boston University Susan Buta, Chair, Speakers Bureau, NESACS Steve Lantos, Chemistry Faculty, Brookline (MA) High School Jerusha Vogel, Chemistry Faculty, Lexington (MA) High School Marilou Cashman, Executive Secretary, NESACS

The high school chemistry teachers were welcomed to the program by Ruth Tanner (University of Massachusetts Lowell), Chair of the NESACS Education Committee and Chair of the Connections to Chemistry program. Steve Lantos, Chair of the High School Education Sub-committee (NESACS), welcomed his high school colleagues. He highlighted the ACS resources available for high school teachers, and encouraged them to utilize these resources. Morton Hoffman discussed the letter in their written program from Bill Carroll, the ACS President-Elect that encouraged the teachers to participate in a survey intended to gather data about a proposed associate membership in the ACS CHED for chemistry high school teachers. Survey cards were included.

Following the opening, workshops were offered to showcase the ACS resources for high school chemistry teachers and students. Four Simultaneous Workshops were offered in Two Sessions: Session I: 4:30 – 5:15 Session II: 5:25 – 6:10

Workshop A: Turn Them into Writers Carolyn Collins Petersen, Science Writer and VP of Loch Ness Productions

Workshop B: The Real CSI Lab William Hebard, Forensic Chemist, Massachusetts State Police Crime Laboratory

Workshop C: Cows Eat Grass; People Eat Pasta (NCW workshop) Edwin Jahngen, Biochemist, Department of Chemistry, University of Massachusetts Lowell

118

Workshop D: Bonding and Molecular Graphics (A two-session workshop, 4:30 - 6:10 PM) Frank Gorga, Department of Chemical Sciences, Bridgewater State College The evening program included dinner and a talk titled Vampires, Rockets and the Hot Zone-Confronting Emerging Infectious Diseases by Mark Klempner, M.D., Director of the National Biocontainment Laboratories (National Center for Emerging Infectious Diseases and Biodefense) and Associate Provost of Research at Boston University’s Medical Campus.

The Connections program received substantial material assistance from the ACS, and the editorial staff of the Journal of Chemical Education:

ACS SCHOLARS PROGRAM (Morton Hoffman, Chair)

ACS Scholars: 2003-2004 academic year.

This is the fourth year for the involvement of the NESACS in the ACS Scholars Program. The NESACS sponsored one student, Jullian Smith, a freshman chemical engineering major at MIT. In the 2003-04 academic year, 23 Scholars studied within NESACS: HARVARD UNIVERSITY Jessica Bazick Mark Garro Roy Hughes, Jr. Melissa McCreery Durrell Robinson Sharon Doku Chikezie Eseonu Christina Ann Fields

119

NORTHEASTERN UNIVERSITY Mark Michelman Ryan Richardson

TUFTS UNIVERSITY Camille Petersen

NESACS Commitment to Support ACS Scholars Program

Dear Robert Hughes;

On behalf of the Northeastern Section (NESACS) I am pleased to inform you that the NESACS Board voted at the February 12th 2004 meeting to extend our financial support to the ACS Scholars Program. Our last financial commitment expired at the end of 2003. The Section wish to renew this commitment to an outstanding program to continue to increase the diversity and vibrancy of Chemistry and the Society. The Northeastern Section will contribute the sum of $2500 each year for four years ( 2004-2007) to the ACS Scholars Program.

NESACS Treasurer, Jim Piper will work with ACS office on the details of the financial transaction.

Best regards

Jean A. Fuller-Stanley Ph.D. Professor and Chair, Chemistry Wellesley College, Wellesley, MA 02481 Phone: 781 283 3224 FAX: 781 283 3642 E-mail: [email protected] NESACS Chair 2004

Invitation to Attend Section Meetings

Subj: Welcome to the ACS Scholars Date: 01/30/04 1:55:34 PM Eastern Standard Time From: [email protected]

120

A flyer (suitable for framing) in rtf format about the meeting is attached. Boston College is conveniently reached via the "T" on the "B" Green Line (Commonwealth Avenue). For travel directions and more information about NESACS, go to ; current (and past) issues of The NUCLEUS, the NESACS monthly newsmagazine, are availabe in pdf format at that site.

I hope you will be able to come to the meeting on February 12, meet some of the younger (and older) chemists of Eastern Massachusetts and New Hampshire, and begin your professional networking. If you intend to come, please contact Marilou Cashman, the NESACS administrator, by telephone at 800-872-2054 or via e-mail no later than noon on February 5 in order to secure your seat at the dinner.

While you have your calendar open, please note the remaining NESACS meetings of this academic year: March 11, April 15, May 13. I promise to send you invitations to attend in a timely fashion.

Until we meet, I want to wish you good luck with your studies and success in everything chemical.

Morton Hoffman *******************************************************************

121

122

EDUCATION COMMITTEE High School Subcommittee Stephen Lantos, Subcommittee Chair

High School Subcommittee Members

Stephen Lantos, Chair Peter Nassiff Avery A. Ashdown Examination Ruth Tanner Lyman C. Newell Grants David Olney Aula Laudis Society Wallace J. Gleekman Theodore William Richards Award

Avery A. Ashdown High School Chemistry Examination Contest & United States Chemistry Olympiad Team (Ashdown Committee: Peter Nassiff, Chair; Steve Lantos, Wally Gleekman) (Olympiad Section Coordinator: Steve Lantos)

The HS Education Committee continues to sponsor and run the annual Avery Ashdown High School Examination Contest. Since the early 1970s, the exam has increased participation to include over 35 participating schools from across the section with well over 120 students sitting for the exam each spring. Peter Nassiff will continue to head the exam writing and administration of the Ashdown Exam.

Top scorers from the exam are eligible to participate in the United States National Chemistry Olympiad, and though we did not have any competitors to compete for a place on the US Team in 2004, in recent years we've sent students from the section to compete amongst a select group of only 20 students nationwide to vie for a spot on the team. Maybe in 2005 . . .

Cash prizes are awarded to the top five scorers; honorable mention certificates are given to the students earning the top five scores at each of the two levels--first and second year.

The 2004 awardees were: Ashdown Examination Awards: First Place / Simmons College Prize Clara Blättler Brookline High School Second Place Tzyy-Nong Liou Brookline High School Third Place T. Y. Albert Chen Lexington High School Fourth Place Sunny Lou Wayland High School Fifth Place Joshua Kaitz Framingham High School Sixth Place Song Wang Acton-Boxborough High School Seventh Place (tie) Andrew Shu Andover High School Seventh Place (tie) Vladimir N. Mirkin Brookline High School

123

Adam E. Sandel Brookline High School Jarrod Shaheen Masconomet High School Caroleen J. Verly Wayland High School Joshua M. Weiner Andover High School Kathleen T. Xie Belmont High School

Lyman C. Newell Grants Ruth Tanner, Chair

The Lyman C. Newell Grants provide financial assistance to high school teachers in the geographical area of the Northeastern Section of the ACS to subsidize the cost of attending the annual summer conference sponsored by NEACT, the New England Association of Chemistry Teachers. The grants are administered by the Newell Grants Committee, all of who are high school chemistry teachers. The Committee administers the grant process starting with the publicity to the awarding of the grants. The Committee coordinates its activities with the Chair of the Education Committee and the President of NEACT.

The Northeastern Section of the American Chemical Society has awarded four Lyman C. Newell Grants for the 66th Annual Summer Conference of the New England Association of Chemistry on Astronomy and Chemistry. The grants of $225.00 each, that partially cover the cost of the conference, were awarded to:

Linda Ryan of Shrewsbury, MA Douglas Baker of Center Barnstead, NH Cheryl Nowak or Rockland, MA Pamela Bergquist of Somerville, MA.

This four-day conference on extra-terrestrial chemistry explored the chemical interactions and processes on the Earth and other planets. The conference was held at Brown University in Providence, RI from Monday, August 2nd through Thursday, August 5th, and was co-sponsored by NEACT, NASA/Brown University Northeast Planetary Data Center and the NASA/Rhode Island Space Grant Program

The Lyman C. Newell Grants commemorate a former chair of the Northeastern Section who was a distinguished chemist, teacher, and historian of chemistry. For many years he was chair of the Chemistry Department at Boston University. Lyman Newell served as the first president of NEACT from 1889 to 1900 and expressed a continuing interest in training chemistry students throughout his long career. His efforts are celebrated by grants that bear his name.

Aula Laudis Society (Committee: Dave Olney, Chair; Wallace J. Gleekman, Kathy Skelly, Helen O’Keefe)

The Section recognizes outstanding secondary school teachers of chemistry by naming them to the Aula Laudis Society at the Annual Education Awards Night conducted in May. In 2004, four area teachers were inducted into the Society; i.e.,

John Mauch Braintree High School Cary Kilner Somerset High School (NH) Coretta Tam Newton Country Day School Marianne McChesney Newton South High School

124

Theodore William Richards Award (Committee: Wallace J. Gleekman, Chair; Emily Dudek, Christopher Doona, Martin Idelson)

The Theodore William Richards Awards for Excellence in Teaching of Secondary School Chemistry were awarded to Valerie J. Lechtanski Hopkinton High School Gary Liptak Laconia (NH) High School

SAMPLE FORMS USED IN HIGH SCHOOL AND COLLEGE MAILINGS / WEB POSTINGS

NORTHEASTERN SECTION AMERICAN CHEMICAL SOCIETY

ADMINISTRATIVE SECRETARY PHONE OR FAX 23 COTTAGE STREET (508) 653-6329 NATICK, MA 01760 MA AND NH ONLY E-MAIL: [email protected] (800) 872-2054

TO: High School Chemistry Teachers FROM: Steve Lantos, Chair, High School Education Committee DATE: February 23, 2004 NOTE: Please refer to the website of the Northeastern Section for Ashdown Examination information and registration forms. The URL is http://www.nesacs.org

This year's Avery Ashdown High School Chemistry Examination Contest of the Northeastern Section of the American Chemical Society will take place on SATURDAY, APRIL 3, 2004, starting at 9:00 a.m. at SIMMONS COLLEGE 300 The Fenway Boston, MA 02115

At Simmons, we will be using rooms in the Science Building which is directly behind the Main College Building. Free parking will be available in the college parking lot located off Avenue Louis Pasteur. Parking permits will be issued at Simmons.

Each high school in the Northeastern Section may be represented by a maximum of five (5) participants selected by their school or teachers. (One alternate may be named on the registration form, but only five students will be tested.) Winners of cash awards and honorable mention awards in previous years are not eligible to compete for Ashdown recognition; however, they may compete to become eligible for the Olympiad Examination. Cash awards will be given to the students with the top five (5) scores. Honorable mention awards will be given to five (5) first-year and five (5) second-year students with the next highest scores. In addition, each winning student will be invited, along with his/her teacher, to be guests of the Northeastern Section at its May, 2004, dinner meeting and will be given appropriate recognition. SCORES WILL BE REPORTED TO TEACHERS VIA E-MAIL IF ADDRESSES ARE PROVIDED ON THE TEACHER REGISTRATION FORM.

Top scorers in the Ashdown Examination will be eligible to take the qualifying exam for the Unites States Chemistry Olympiad Team on April 17. PLEASE SEE THE GUIDELINES ON THE REVERSE SIDE OF THIS MEMO FOR MORE INFORMATION ABOUT THE ASHDOWN EXAMINATION AND THE INTERNATIONAL CHEMISTRY OLYMPIAD.

Please return the enclosed STUDENT and TEACHER REGISTRATION FORMS by Tuesday, March 30, 2004, to register your students for the Ashdown Exam. Each student should bring #2 pencils to the examination. Students may use programmable or graphing calculators provided the memory is erased from the programs. This will be verified by proctors before the exam.

Along with the enclosed form for registration of students, it is requested that each school send $5.00 per student ($25 maximum) in order to help defray the cost of prizes and awards. The check should be made out to NESACS - Ashdown Exam. (Please DO NOT SEND PURCHASE ORDERS.)

125

Please be certain that your students make careful note of the exact information about the examination since this is not an official function of the college involved and few on campus will be aware of essential details. Any questions about the details of the examination should be directed, preferably by e-mail, to: Dr. Peter Nassiff Science Department Burlington High School Burlington, MA 01803 781-270-2923 e-mail: [email protected] Questions relating to registrations for the exam should be directed to: Marilou Cashman (508) 653-6329 or (800) 872-2054

e-mail: [email protected] Note: This information, with the Guidelines and Registration Forms, can be found on the internet at http://www.nesacs.org

126 2004 AVERY A. ASHDOWN EXAMINATION GUIDELINES

1. Entrants. The Ashdown Examination has traditionally been divided among two populations of students: first- year and second-year/AP level. Difficulty has arisen in the past in defining those students who are taking chemistry as a second-year course but do not follow the AP curriculum and those who are taking a first-year course but do follow the AP curriculum.

It is NOT the intent of the Examination Committee to narrow and define academic guidelines of entrants; the simple goal of the exam is to test for chemical knowledge. Thus, students will be defined as: first-year (a first exposure to chemistry) and second-year (a second-year exposure to chemistry), regardless of an individual's background, course name, or curriculum. We feel this will most fairly include as many as possible in taking the examination. THERE WILL BE TWO SEPARATE TESTS THIS YEAR -- one for those in the first year of chemistry and a second exam for all others.

2. Scoring and Prizes. As before, five (5) cash awards will be given for the top scores of ALL entrants. Duplicate scores in the top five will be considered as two of the five scores. Scoring is determined by raw score. The next five scores for both first and second year will be awarded an Honorable Mention and certificate, regardless of duplicate scores. Recognition will also be given to each teacher. It is strongly felt that students and teachers must be given greater recognition than before.

3. The Exam. Both examinations -- for first-year students and for students in a second or later year of studying chemistry -- will remain with 100 questions.

4. Olympiad. Those successful students wishing to compete in the International Chemistry Olympiad will be selected from the top scores, regardless of level. Should there be a duplicate score, both entrants may be considered. As before, only two students from any school may compete.

5. Other. Students may use programmable or graphing calculators provided the memory is erased from the programs. This will be verified by proctors before the exam. It is felt that as much time as possible during the exam should be spent doing chemistry, not math. Within one week of the exam date, student scores will be mailed to the participating schools notifying teachers of the winners. A breakdown of the range of scores and high scorers will be included along with a distribution of the types of chemistry questions included on this year's examination.

Should there be questions about the examination, please contact Dr. Peter Nassiff at (781) 270-2923 or by e-mail to [email protected]. Questions about registrations for the exam should be addressed to the Administrative Secretary by phone or fax at the Section Office (800) 872-2054 or by e-mail - [email protected]

Dates

Registration Deadline for Ashdown Examination: Tuesday, March 30, 2004

Ashdown Exam Saturday, April 3 Simmons College 9:00 a.m.

The Olympiad Exam will be administered on Saturday, April 17, at 9:00 a.m. at Simmons College to the top scorers on the Ashdown Exam. These students will be notified by telephone within a day or two of the Ashdown Exam.

Note: This information may also be found on the internet at http://www.nesacs.org

127

Call for Applications – Grants-in-Aid NORTHEASTERN SECTION AMERICAN CHEMICAL SOCIETY

ADMINISTRATIVE SECRETARY PHONE OR FAX 23 COTTAGE STREET (508) 653-6329 NATICK, MA 01760 MA AND NH ONLY E-MAIL: [email protected] (800) 872-2054

September 1, 2004

To: Chairs of Departments of Chemistry, Chemical Engineering, Biochemistry & Molecular Biology (Colleges and Universities in the Northeastern Section of the American Chemical Society

From: Professor Ruth Tanner, Chair Education Committee of the Northeastern Section of the American Chemical Society

Subject: Applications for Grants-in-Aid for Undergraduate Researchers to Attend the National Meeting of the American Chemical Society, San Diego, California, March 13-17, 2005

I am pleased to announce the continuation of the Northeastern ACS Section Grants-in-Aid program to assist undergraduates to attend the spring National ACS Meeting and present a paper on their research at the Undergraduate Research Poster Session. The 229th National Meeting will be held in San Diego, California, March 13-17, 2005.

Grants-in-Aid of $250 will be awarded to each of four undergraduates who are enrolled in the Chemistry, Chemical Engineering, Biochemistry or Molecular Biology Departments in the colleges and universities within the Northeastern Section. One condition of the Grants-in-Aid is that the award must be matched, at a minimum, by the institution.

Two copies of the application form are enclosed for you to give to undergraduate researchers who may wish to apply. Please photocopy if additional forms are needed for your students. In addition, application forms may be obtained from the NESACS web site at http://www.nesacs.org. I will be happy to answer any questions you or your students and faculty might have about the Grants-in-Aid program or the application form. I can be reached at (978) 934-3662; e mail: [email protected].

Enclosed are announcements of the Grants-in-Aid program and the Undergraduate Research Poster Session for you to post and distribute in your Department. I thank you for your help in making the activities of the Section known to your students.

The deadline for receipt of completed applications for the Grants-in-Aid is November 3, 2004. Applicants will be notified of the results by e-mail on November 8, 2004. Abstracts for the Undergraduate Research Poster Session must be received by electronic transmission at ACS National Headquarters by November 22, 2004.

Completed Grants-in-Aid applications are to be sent to: Professor Ruth Tanner University of Massachusetts Lowell Chemistry Department, Olney Hall 1 University Avenue Lowell, MA 01854-5047

128

Call for Papers

Undergraduate Research Poster Session

at the

229th National Meeting of the American Chemical Society

San Diego, California March 13 – 17, 2005

The ACS invites undergraduate students to submit abstracts of their research papers for presentation at the Undergraduate Research Poster Session (URPS), which will be part of the extensive programming for undergraduates at this national meeting. Submit your abstract electronically by November 22, 2004 to . Click on the CHED division and then select the URPS site that is appropriate to the subject of your paper. Please follow the directions carefully.

For further information, contact:

LaTrease Garrison ACS Student Affiliates Program 1155 Sixteenth Street, NW Washington, DC 20036 Tel: (800) 227-5558, ext. 6166 e–mail: [email protected]

129

Call for Applications The James Flack Norris and Theodore William Richards Undergraduate Summer Research Scholarships

Research awards of $3250 will be given for the summer of 2004. The student stipend is $2750 for a minimum commitment of ten weeks of full-time research work. The remaining $500 of the award can be spent on supplies, travel, and other items relevant to the student project.

Institutions whose student/faculty team receives a Norris/Richards Undergraduate Summer Research Scholarship are expected to contribute toward the support of the faculty members and to waive any student fees for summer research. Academic credit may be granted to the students at the discretion of the institutions.

Award winners are required to submit a report (~5-7 double-spaced pages including figures, tables, and bibliography) of their summer projects to the NESACS Education Committee by November 5, 2004 for publication in The Nucleus. They are also required to participate in the Northeast Student Chemistry Research Conference (NSCRC) in April 2005.

Eligibility: Applications will be accepted from student/faculty teams at colleges and universities within the Northeastern Section. The undergraduate student must be a chemistry, biochemistry chemical engineering, or molecular biology major in good standing, and have completed at least two full years of college-level chemistry by summer, 2004.

Application: Application forms are available on the NESACS web site at http://www.nesacs.org. Completed applications are to be submitted no later than April 9, 2004 to the Chair of the Selection Committee:

Professor Edwin Jahngen University of Massachusetts Lowell Chemistry Department, Room 520 265 Riverside Street, Olney Hall Lowell, MA 01854-5047

Notification: Applicants will be notified of the results by e-mail on April 23, 2004 with written confirmation to follow.

130

Informational Letter – Summer Research Scholarships

NORTHEASTERN SECTION AMERICAN CHEMICAL SOCIETY

ADMINISTRATIVE SECRETARY PHONE OR FAX 23 COTTAGE STREET (508) 653-6329 NATICK, MA 01760 MA AND NH ONLY E-MAIL: [email protected] (800) 872-2054

January 29, 2004

To: Chairpersons of Departments of Chemistry, Chemical Engineering, and Biochemistry (Colleges and Universities in the Northeastern Section of the American Chemical Society)

From: Professor Ruth Tanner (University of Massachusetts Lowell), Chair Education Committee of the Northeastern Section of the American Chemical Society

Subject: Applications for Norris/Richards 2004 Undergraduate Summer Research Scholarships

The Northeastern Section of the American Chemical Society (NESACS) established the James Flack Norris and Theodore William Richards Undergraduate Summer Scholarships to honor the memories of Professors Norris and Richards through the promotion of research interactions between undergraduate students and faculty. Research awards of $3,250 will be given for the Summer of 2004, which include a stipend to the student of $2,750 for a minimum of ten weeks of full-time research work; the remaining $500 can be spent on supplies, travel, and other items related to the student project. I am asking for your help to make sure that all those student/faculty pairs who might be interested in applying for support are informed of this program. The deadline for receipt of the completed applications (with two supporting letters) is April 9, 2004. Applicants will be notified of the results on April 23, 2004. Completed application must be submitted to the Chair of the Selection Committee:

Professor Edwin Jahngen University of Massachusetts Lowell Chemistry Department, Room 520 265 Riverside Street, Olney Hall Lowell, MA 01854-5047

Enclosed is an announcement of the program. I ask you to distribute and post it where students and faculty will see it. I would also appreciate your help in making sure that students who might qualify for the scholarships, but who are majors in departments not covered by this mailing, have an opportunity to obtain the information.

Institutions whose student/faculty team receives a Norris/Richards Fellowship are expected to contribute toward the support of the faculty member and to waive any student fees for summer research. Academic credit may be granted to the students at the discretion of the institutions. Award winners are required to submit a report of their summer projects by November 5, 2004, for publication in The Nucleus, and to participate in the NESACS Northeast Student Chemistry Research Conference in April 2005.

Application forms are available on the NESACS web site at http://www.nesacs.org. If you, your students, or your faculty have any questions about the program or the application, call me at (978) 934-3662, or contact Professor Edwin Jahngen, Chair of the Selection Committee at (978) 934-3693.

Thank you for helping to make this program known and for promoting undergraduate research as a vital part of chemical education.

131

Call for Nominations – Teaching Award

Northeastern Section AMERICAN CHEMICAL SOCIETY

ADMINISTRATIVE SECRETARY PHONE OR FAX 23 COTTAGE STREET (508) 653-6329 NATICK, MA 01760 MA AND NH ONLY E-MAIL: [email protected] (800) 872-2054

THEODORE WILLIAM RICHARDS AWARD FOR EXCELLENCE IN TEACHING SECONDARY SCHOOL CHEMISTRY

ANNOUNCEMENT OF AN AWARD PROGRAM

February 2004

Dear Science Department:

Do you know an excellent Chemistry teacher to nominate for the 2004 Theodore William Richards Award for Excellence in Teaching Secondary School Chemistry sponsored by the Northeastern Section of the American Chemical Society? We feel that there are many outstanding and exceptional Chemistry teachers in the Northeastern Section, so please take the time to nominate one of the deserving faculty members from your school.

The prestigious Theodore William Richards Award for Excellence in Teaching Secondary School Chemistry is presented annually to a teacher who demonstrates exceptional innovation and dedication in inspiring students (majors and non-majors alike), communication in the principles of chemistry in and out of the classroom, and leadership in influencing and mentoring other chemistry teachers. Sound like someone you know or work with? Then use the attached nomination form and recognize that teacher’s talents.

Nominations by STUDENTS (current or former), COLLEAGUES, DEPARTMENT HEADS, or INDIVIDUALS who choose to self-nominate are eligible for consideration. The deserving recipient will be honored at the Education Night ceremony in May and presented with a $1,500 cash prize and Certificate of Recognition.

Thank you for your attention in bringing recognition to the talented Chemistry teachers of the Northeastern Section, and hopefully the next deserving recipient of the prestigious Theodore William Richards Award will be from your school.

Please send nomination forms by March 31, 2004 to: Dr. Wallace J. Gleekman, Award Committee Chair 35 Rangeley Road West Newton, MA 02465 e-mail: [email protected].

Very truly yours,

Dr. Wallace J. Gleekman

This information can be found on the website of the Northeastern Section, ACS: http://www.nesacs.org

132

Sample Education Committee Items from The Nucleus 2004

133

134

135

136

1$/.13.%3'$$22$+$- 6 1#".,,(33$$ $)∂∫¨∑Ø!∞≥≥∂ "Ø®∞π The 18th Gustavus John Esselen Award for Chemistry in the Public Interest was presented on April 15, 2004 to Dr. James W. Jorgenson, William Rand Kenan Jr. Distinguished Professor of Chemistry, University of North Carolina at Chapel Hill, for his research leading to the development of capillary electrophoresis. Public announcement of the award appeared in the March 22nd issue of Chemical and Engineering News.

The award reception and dinner were held at the Harvard Faculty Club with approximately 100 people in attendance. The award ceremony and recipient’s address, “The Magic of Capillaries in Chemical Separations and Analysis,” were held in the Pfizer Lecture Hall in Mallinckrodt Chemistry Building. The award recipient was introduced by Dr. Robert T. Kennedy, University of Michigan. The award, consisting of a medal and a check for $5000, was presented to Dr. Jorgenson by Mr. Gustavus John Esselen IV.

The members of the 2004 Award Committee were: E. J. Billo, Boston College; Paul Vouros, Northeastern University; William Klemperer, Harvard University, Robert Langer, MIT; Harry Gray, CalTech; Joseph DeSimone, UNC Chapel Hill; Madeleine Jacobs, C&E News.

Dr. Paul Vouros was elected chair of the Esselen Award Committee for 2005, with duties to commence after the Esselen Award events for 2004.

Respectfully submitted, E. Joseph Billo, Chair Esselen Award Committee, 2004

Dr. James W. Jorgenson Esselen Award Recipient 2004

137

Invitation to Esselen Award Dinner

138

Esselen Award Dinner Program

139

140

141

142

143

144

REPORT OF THE GOVERNMENT RELATIONS COMMITTEE - 2004 Doris I. Lewis, Chair

Members: Michael Hearn, Tim Rose, Michael Strem, Doris Lewis

Our Section has three active participants in the ACS Joint Board-Council Committee on Chemistry and Public Affairs. Dr. Michael J. Hearn is a committee member and is Chair of the Grassroots Advocacy and Membership Subcommittee. Timothy L. Rose serves on the Awards Subcommittee. Doris Lewis is a committee member.

Dr. Hearn, Dr. Rose, and Dr. Lewis attended the CCPA meeting in Washington on April 19 and 3rd annual ACS Legislative Summit April 20, making several congressional visits. The Legislative Summit focused on the Department of Energy's Office of Science; the Office of Science funds 40 percent of the federal government's investment in physical science research. Subsequent to our congressional meetings, the Senate Department of Energy's Office of Science Dear Colleague Letter was sent to Senate Appropriator with 55 Senators signing on. One of the last sign-ons was Senator Kerry; according to Bradley R. Smith, our legislative Associate for Grassroots Programs, our meeting with Senator Kerry’s staff helped make this happen. Our NESACS CCPA members also attended the CCPA committee meeting at the Philadelphia national meeting in August. Among the agenda items were a preliminary endorsement of a joint energy policy statement from ACS and the. The similar goals of the AIChE and the ACS regarding public policy issues and legislative action were discussed. AIChE

Four NESACS members, Michael Hearn, Tim Rose, Mike Strem, and Doris Lewis, met with Rep. Tierney in his Peabody office and with Rep. Lynch’s legislative assistant in his Boston office on July 19. Ray Garant of the Office of Legislative and Government Affairs accompanied us on these visits and conducted a briefing breakfast prior to the meetings. Support for funding of NSF in the current budget was the major request we made of the congressmen. OLGA provided us with statistics regarding current NSF expenditures in the state and affects congressional districts as part of the standard briefing for the visits.

As CCPA members, Dr. Hearn, Dr. Rose, and Dr. Lewis were asked to review and approve an ACS Energy Policy Statement . This statement was developed by a special working group of ACS and AIChE leaders; drafts of the statement were reviewed by over a dozen units within ACS, including CCPA.

Respectfully submitted, Doris Lewis

145

REPORT OF THE LOCAL ARRANGEMENTS COMMITTEE - 2004 Mary Burgess, Chair

The following is data for the meetings held during 2004. January 8, 2004 Harvard Faculty 80 people Dr. Mark Murko Joint with BAGIM Club February 12,2004 Boston College 72 people Dr. William Carroll President ACS March 11,2004 Harvard Faculty 88 people Professor John Ross Richards Medal Club Award April 15,2004 Harvard Faculty 97 people Professor James Esselen Award Club Jorgenson May 13, 2004 Northeastern 120 people Dr. Koji Naganishi Education Meeting. University Awards Ceremony September9,2004 Radisson Hotel, 100 people MCG Symposium: Vendor Fair and Woburn MA New Uses for Old Career Program Drugs October 14,2004 Wellesley College 100 people Francis Coppa, Esq. Henry Hill Award and 50-Yr. Member Recognition November MIT 85 people Dr Richard N. Zare James Flack Norris 11,2004 Award December 9,2004 Holiday Inn, 50 people MCG Symposium: Brookline MA Kinase Targets

REPORT OF THE LONG-RANGE PLANNING MEETING

Long-Range Planning Meeting June 22, 2004 5:00 p.m. – 7:00 p.m. Science Center – Wellesley College Wellesley, MA

AGENDA

146

MINUTES

Long-Range Planning 2004 June 22, 2004

Fuller-Stanley, chair of NESACS, presiding

Election results announced (note: Patricia Mabrouk, chair-elect, likes to be called Pam). Please refer to e- mail from Marilou Cashman of 06-05-04.

‹ YCC Proposal: See proposal read per Mike Strem’s e-mail of June 16, 2004 (See Below):

Dear Members of the NESACS Board:

3) We request that the Board commit to support the 2005 exchange to a maximum of $12,000. for twelve students plus the NESACS Chair (or designate) and the NESACS-YCC Chair (or designate).

147

(Treasurer-Piper) $7000 company donations, $6000-career fair, $4000-baseball tickets (Strem) Career fair was helped by presence of the international students. (Tapper) Both students and companies positively received career fair. Chemluminaries were won (and this year nominated) for all four years that YCC has functioned. (?) Who pays what? Why is this year less expensive then last year? (Strem) The host country funds room and board, travelers pay transportation. This year we are travelers. (Viola) How does the treasurer feel about funding this proposal? (Treasurer): If we budget 12K we’ll make it through the year. (Viola) Would like to see the Exchange Committee open up to a broader range of students, accompanying professionals, NESACS Board members, etc. (Tapper) YCC advertises this program in the Nucleus and on YCC’s website. (Mabrouk) suggests improvement in outreach via letters to the dept chairs or students themselves via e- mail. (Lewis) Good motivational tool for joining national and locals ACS. (Tanner) Moves question. (Chorghade) seconds. Approved (Strem) moves proposal (Chorghade) seconds. Approved. The proposal will be funded.

‹ Board of Publications-The Nucleus

Why Financial overruns? (Chorghade) Printing had extra billing that was not budgeted.

148

(Gale) Ao Zhang- (Production end), and yet to be named 4th position part of the editorial crew, four proofreaders, plus other minor editors. (Viola): Nucleus is vital tool; feels volunteer working staff can’t put the time and energy into what the job is really worth. Supports Mike Strem’s initial motion. It’s too risky to wait until Sept. (Gordon) has every confidence in the team. Doesn’t see any indication that a dip in service will occur. Chair requests phone number, etc of editors (Gordon) Will send all info to Marilou Cashman. (Buta) What actually happened to finances of Nucleus--was it resolved? (Chorghade) formatting numbers, equations, and budgets into final copy needed extra help from the printer mostly due to inexperience with the computer programs needed to format the figures. (Walworth)-Arno supported waiting with remuneration at last BOP meeting. (Simon) Was associate editor for many years and supports volunteer editorial board. Remuneration is not the motivator. (Lewis) Requests much closer communications with BOP. Ideal would be a written recommendation plus representation in Sept and following months. (Strem) We have a tradition of paying the editor (or call it an honorarium). He suggests keeping the tradition going. (Buta) Requests safeguards spelled out in case Nucleus deadlines missed or quality suffers. (Gordon) Safeguards already proven during this transition. Chair: two questions for BOP Honorarium amount? To be discussed Who is responsible for deadlines? Managing editor (Tanner) Question called. (Tapper) seconds. Question called

Motion Vote: BOP to provide NESACS board with recommendation for remuneration by Sept. NESACS board meeting: approved, 2 opposed no abstentions. Motion approved.

(Viola) Requests written recommendation from BOP prior to actual NESACS board meeting. Chair asks Gordon to follow up.

‹ Finances (Mabrouk) Only one SEED student this year so requests $2000 of $6000 budget to support HS teacher. Pam worked with this teacher last year. Became interested in research and requested a research opportunity. (Lewis) Supports proposal and motions that $2000 will be allowed to transfer to HS teacher to support summer research. (Tapper) seconds- Motion approved.

‹ Treasurer Report. Total assets- remarkably stable considering stock market. Treasurer feels we are in reasonable state.

149

‹ Electronic Communications Webmaster. (Chair) We may need a different model in the future. Sam is doing a great job, but he has received a grant and may not be able to spend more time on the site. NJ / NY both employ webmasters for long term. NJ is very different then our site. Our site may need revamping. (Tanner) National recommended our board hire a paid Webmaster. (Gordon): BOP cost/benefit may not be there since there’s not a lot of work to be done to maintain the website at this point. (Strem) Should we put paid advertising on our Website? (Gale) 5% of our NESACS membership goes onto our website. If we get 1000 member hits, we would go for web advertising. We get hits from outside the membership. Gale feels our site is among the best from what he can see. (Simon) –NY does not have a Nucleus or equivalent-maybe their website fills that gap. Chair-We need to be forward-looking. (Gale) agrees because we should always strive for improvement in the future. (Tanner) We should review the design of site with questions such as: Is the site information friendly? Can you immediately find what you need? Does the organization of material need to be looked at? Example: should we have search capabilities on our home page? (Tapper) Job postings may need to be more pronounced. (Chorghade) Novartis specifically asked for that sort of help.

Meeting adjourned.

(Notes taken by Susan Buta)

150

MEDICINAL CHEMISTRY GROUP Annual Report 2004 Pamela Nagafuji, Chair

The Medicinal Chemistry Group (MCG) of the NESACS held three well-attended technical medicinal chemistry mini-symposia this year covering the following topics:

• Natural products as starting points in drug design • New uses for old drugs • Kinases

These symposia continue to provide a means for area NESACS scientists to present their research, to foster collaborations, to further professional development and to pursue personal scientific interests in areas outside their expertise and are open to the general public. For the year 2004 the MCG demographically represented over 50% of the sections 6,500 plus members with an annual operating budget of $7,500.

The following is a description of the three symposia held this year.

September Meeting Northeastern Section The 856th Meeting American Chemical Society of the Northeastern Section of the American Chemical Society

Thursday - May 27th, 2004 Radisson Hotel - 15 Middlesex Canal - Woburn, MA

2.30 pm Refreshments 3.00 pm Introductory Remarks Norton Peet, Aurigene Discovery Technologies, Lexington, MA 3.15 pm Future potential of Natural Products as Quality Leads- Attempts for a Qualitative and Quantitative Assessment Matthias Gehling, Bayer AG, Bayer Health Care, Elberfeld, Germany 4.00 pm New Spectroscopic Methods for Natural Products Discovery Frank Koehn, Wyeth Research, Pearl River, NY 4.45 pm Natural Product-Inspired Compound Libraries - From Synthesis to Screening to ChemBank John Tallarico, Harvard Institute of Chemistry and Cell Biology, Boston, MA 5.30 pm Social Hour 6.30 pm Dinner 7:45 pm Industrial Natural Products Research- Challenges and Opportunities Frank Petersen, Novartis Pharma Ltd., Basel, Switzerland

THE PUBLIC IS INVITED

151

Symposium: Natural Product Scaffolds as Starting Points for Drug Discovery Organized by the Medicinal Chemistry Section of the Northeastern Section, American Chemical Society

Norton Peet Norton Peet will introduce the topic and give examples and suggest new starting points where mechanistic work on natural products has suggested a lead compound, or where traditional medicine has defined a potentially good drug- like compound. ------Norton Peet is the Chief Executive of Aurigene Discovery Technologies. Prior to joining Aurigene, he was Vice President of Discovery Alliances at ArQule, Inc. Previous to that appointment he was Head of Medicinal Chemistry and Distinguished Scientist at Aventis. Norton serves on several editorial boards and has authored 140 technical articles and books. He holds 65 US Patents, which largely cover enzyme inhibitors and receptor ligands for therapeutic targets in the areas of CNS, cardiovascular, metabolic and respiratory diseases and oncology

Matthias Gehling Future potential of Natural Products as Quality Leads- Attempts for a Qualitative and Quantitative Assessment The importance of natural products as drugs for life science applications can easily be drawn from actual sales figures of marketed products and their impact as biochemical tools as well as inspiring starting point for chemical/biological optimization to become a useful product. However, regarding the identification of new innovative bioactive compounds from nature, the value assessment of certain biological material towards molecular diversity and thus improvement of probability of success, is still challenging. The intrinsic high costs of natural product research must be minimized by optimizing the technology platform around this research and speeding up the process from hit to lead. This presentation will emphasize on the potential of natural products and will touch on perspectives how they can contribute to the value generation chain of the life science industry in the future.

Matthias Gehling received his Ph.D. in Chemistry in 1989 from the University of Münster, Germany. He first joined Bayer AG (Leverkusen, Germany) as a research scientist, after working several years in dyes and textile processing chemicals division, he moved to the central research division to conduct research on natural products. In 1998 he joined Bayer AG, Health care and pharma research division, Elberfeld, Germany, where he is now director and head of natural products research.

John Tallarico Natural Product-Inspired Compound Libraries - From Synthesis to Screening to ChemBank The Harvard Institute of Chemistry and Cell Biology (ICCB) is engaged in the systematic screening and use of small molecules to perturb complex biological systems at the protein level in order to increase our understanding basic mechanism in biology. This is analogous to the use of classical genetics, where genomic level mutations are used to perturb the functional state of the proteins they encode. The ICCB has invested heavily in creating an integrated chemical synthesis and biological screening platform for use in our chemical genetic and chemical genomic analyses. A detailed description of the overall platform will be presented along with some recent discoveries from within the ICCB. The central output of the ICCB efforts is information about how small molecules interact with biology. We intend to systematically collect and annotate all of the information from our chemical genetic and chemical genomic experiments and make it publicly accessible and available via ChemBank, a new initiative from the National Cancer Institute (NCI, USA) which is centered at ICCB ------John Tallarico is currently Head of Chemical Technology and an Institute Fellow at the Harvard Institute of Chemistry and Cell Biology (ICCB). The Harvard ICCB is a joint initiative of Harvard Medical School and Harvard University where research is focused on developing the nascent field of chemical genetics. Prior to this position, John received his B.A. (1993) in chemistry at Miami University, Oxford, Ohio, USA. Dr. Tallarico continued his studies at Boston College (Chestnut Hill, Massachusetts, USA), receiving his Ph.D. in organic chemistry in 1999.

152

His postdoctoral studies were performed at Harvard Medical School and Harvard University as a Fellow of the Cancer Research Fund of the Damon Runyon-Walter Winchell Foundation under the guidance of Prof. Stuart L. Schreiber. It was at this time that Dr. Tallarico began his work in the field of chemical genetics where he worked with a team of researchers to build the chemical technology platform central to the ICCB discovery efforts. His laboratory is specifically interested in the areas of diversity-oriented synthesis (DOS), solid support/linker chemistries and cheminformatics. His group is generally interested in using chemistry-based approaches to solve any problems faced by the field of chemical genetics. For further information, see http://iccb.med.harvard.edu

Frank Koehn New Spectroscopic Methods for Natural Products Discovery This talk will focus on development and application of new methodologies in NMR and mass spectrometry which have greatly accelerated the detection, isolation and structure elucidation of biologically active natural products. ------Frank Koehn, received his Ph.D. in Biochemistry in 1977 from the University of Wisconsin-Madison. He went on to a 2- year postdoctoral position in natural products chemistry at the University of Pennsylvania, Monell Chemical Senses Center. From there he spent the next 10 years as a researcher at Harbor Branch Oceanographic Institution, Division of Biomedical Marine Research, in Fort Pierce, FL, working in the field of marine natural products drug discovery. In 1994 he joined Wyeth in Pearl River, NY, where he is now Associate Director of Natural Products Chemistry and Discovery Analytical Chemistry.

Frank Petersen Industrial Natural Products Research- Challenges and Opportunities A landmark survey from 2003, published in the Journal of Natural Products showed that a whopping 61% of 877 smallmolecule New Chemical Entities (NCEs) introduced worldwide from 1981 to 2002 can be traced to natural products. Those NCEs include blockbuster categories such as cholesterol-lowering statins and ACE inhibitors. In some therapeutic areas, natural products are the dominant source of successful new compounds: 78% of antibacterials and 74% of anticancer compounds are either natural products, or inspired by a natural-product model. Although natural products are very successful molecules as starting point for new therapeutics, the majority of US pharmaceutical companies terminated their natural products activities and in Japan and Europe the investment in industrial natural products research was reduced substantially during the last decade. The main reasons for termination were the time and cost intensive efforts by contrast to synthetic molecules, however, also the lack of success compared to synthetics as sources for drug discovery and development. The free resources were shifted to new technologies such as genomics and combinatorial chemistry searching for sources of chemical diversity easily accessible via synthesis. By examples on recent launches or compounds now at advanced stages in research or clinical development it will be highlighted what opportunities are generated when industrial natural products are in the research portfolio of drug discovery. Coartem®, the fixed-combination antimalarial drug, jointly developed with Chinese partners and provided at cost to developing countries, is derived from artemisinin, a compound used for centuries in traditional Chinese medicine. Elidel® (pimecrolimus), for the treatment of atopic dermatitis first approved in 2001, is making use of the topical anti-inflammatory properties of the macrolactams, natural substances obtained from soil bacteria. FTY720, in Phase III, a new cornerstone in immune modulation, is a synthetic structural analog of the fungal metabolite myriocin. In a collaboration with scientists at the Dana-Faber-Institute/ Harvard Medical School, Midostaurin® was identified as a potent Flt-3 inhibitor. The staurosporine based kinase inhibitor is currently in clinical trials Ph II for acute myeloblastic leukemia (AML). The identification of unusual sources for secondary metabolites is an important goal of natural products microbiology. During a research collaboration between Novartis and GBF (Braunschweig, Germany), the research groups of Profs. Reichenbach and Höfle isolated highly potent epothilones from Sorangium cellulosum. Interacting with the taxol binding site, these unusual macrolides inhibit the tubulin depolymerization in the low nM range. Epothilone B is currently in clinical Ph II at Novartis Pharma. Only recently, the molecular interaction at the taxol binding domain was elucidated by scientists at Max-Planck-Institute (Göttingen) and Novartis Pharma. ------Frank Petersen studied microbiology at the universities of Hohenheim and Tübingen. From 1988-1991, he did his thesis in the group of Prof. Hans Zähner and isolated the first auto- regulative germination inhibitor of the genus Streptomyces. For this scientific achievement he received the DECHEMA-Award 1991 "New natural products and perspectives for their application". In 1991, he moved to the microbial chemistry group at Ciba-Geigy and was

153

responsible for the natural products microbiology. He implemented a chemical screening approach based on UV- DAD analytics and physiological media variations. By this concept many new natural products could be isolated demonstrating how to unleash the biosynthetic potential of secondary metabolite producers. The development of computer assisted titer optimization strategies could be applied successfully in the development of natural products on production scale. Being promoted to programme head in 1999, Frank Petersen was responsible for the microbiology and resupply activities of epothilone B, a novel tubulin depolymerization inhibitor. During this project, the whole biosynthesis cluster has been sequenced and subsequently patented. The compound is currently in Ph II clinical trials. Since 2001, he helds the unit head position of natural products research at Novartis Pharma

September Meeting Northeastern Section American Chemical Society The 852nd Meeting of the Northeastern Section of the American Chemical Society

Symposium: New Uses for Old Drugs

Organized by the Medicinal Chemistry Section of the Northeastern Section, American Chemical Society

th Thursday - September 9 , 2004 Radisson Hotel - 15 Middlesex Canal - Woburn, MA

7.45 pm New Leads from Old Drugs: The SOSA Approach Professor Camille Wermuth, Université Louis Pasteur, Strasbourg, France

THE PUBLIC IS INVITED

154

Norton Peet Estimates on the present cost for new drugs from pharmaceutical executives - from start to finish - ranges from US$800M to US$1.8B. The timeline cost is 10 - 13 years. These high costs and long timeline make the idea of creating new uses for old drugs very attractive. Existing drugs are known quantities in terms of human safety and bioavailability, and can therefore shorten the time and cost needed for drug development of a new utility. ------Norton Peet is the Chief Executive of Aurigene Discovery Technologies. Prior to joining Aurigene, he was Vice President of Discovery Alliances at ArQule, Inc. Previous to that appointment he was Head of Medicinal Chemistry and Distinguished Scientist at Aventis. Norton serves on several editorial boards and has authored 140 technical articles and books. He holds 65 US Patents, which largely cover enzyme inhibitors and receptor ligands for therapeutic targets in the areas of CNS, cardiovascular, metabolic and respiratory diseases and oncology

George Muller The Two Faces of Thalidomide Thalidomide was discovered and developed in the 1950’s as a non-addicting sedative and made infamous by its teratogenic activity. In the late 50’s thalidomide rapidly became a popular sedative that was removed from the market when its use as a treatment for morning sickness was linked to serious birth defects. The serendipitous discovery of its anti-inflammatory activity in the mid-60’s in the treatment of erythema nodosum leprosum (ENL) in leprosy resulted in its renewed use. The discovery of thalidomide TNF-α inhibitory activity, anti-angiogenic activity and its clinical efficacy in cancer has resulted in renewed interest in thalidomide and its analogs. Celgene began development of thalidomide in 1992 and received FDA approval in 1998 for the treatment of cutaneous manifestations of ENL in leprosy. The major clinical use of thalidomide in the United States is in oncology with a focus on blood cancers. A large number of clinical trials have demonstrated clinical efficacy of thalidomide in the treatment of multiple myeloma. An sNDA for the treatment of multiple myeloma was filed in 2004. Thalidomide is currently being investigated in over 100 clinical trials in a wide range of diseases. Celgene began its drug discovery program at the end of 1992 to discover thalidomide analogs with improved therapeutic indices and improved activity. This research resulted in the discovery of a new class of thalidomide analogs termed IMiDs. The IMiDs are thalidomide analogs with greatly improved in vitro activity that show potent anti-inflammatory activity and anticancer activity. The most advanced IMiD is presently in pivotal clinical trials for the treatment of multiple myeloma and MDS. Thalidomide’s development as a drug and the discovery and the development of the IMiDs will be presented. ------George Muller received his Ph.D. in organic Chemistry in 1981 from the University of California, Santa Barbara. He first joined ZOECON CORPORATION, Palo Alto, California. After working several years at Zoecon he moved to G.D. SEARLE, Mt. Prospect, Illinois, as Senior Research Investigator. In 1992 he joined CELGENE CORPORATION, Warren, New Jersey where he is now serving as Senior Director of Chemistry. Muller has authored several technical articles and holds more than 40 US patents.

Timothy Barberich Evolution of the Improved Chemical Entity (ICE) Strategy

The formation and key milestones of Sepracor parallel the development of a novel drug discovery strategy that has led to an industry wide practice of commercializing isomers and metabolites of existing drugs. By complementing the traditional pathway of medicinal chemistry and high throughput screening, the ICE discovery strategy has resulted in shortened development time-lines, contained risk assessment, and life-cycle management programs of major impact to the pharmaceutical industry ------Timothy Barberich, is the Chief Executive of Sepracor. He served as President and Chief Executive Officer from 1984 through 1999. Prior to founding Sepracor, Mr. Barberich spent 10 years at Millipore Corporation. While at

155

Millipore, he held a variety of marketing, sales, and general management positions. Prior to Millipore, Mr. Barberich held project management and research scientist positions at American Cyanamid Company. Mr. Barberich serves as Chairman of the Board of Sepracor and as a board member of BioSphere Medical and Point Therapeutics.

Professor Camille-Georges Wermuth New Leads from Old Drugs: The SOSA Approach The SOSA (selective optimization of side activities) approach represents a validated alternative to HTS.9-12 It consists of testing “old” drugs on new pharmaceutical targets. The aim is to subject to pharmacological screening a limited number of drug molecules that are structurally and therapeutically very diverse and that have known safety and bioavailability in humans and thereby shorten the time and the cost needed for a hit identification. ------Camille-Georges Wermuth, was Professor of Organic Chemistry and Medicinal Chemistry at the Faculty of Pharmacy, Louis Pasteur University, Strasbourg, France from 1969 to 2002. He founded The Prestwick Chemical Inc. company in 1999 in which he acts as President and CSO. Professor Wermuth’s main research themes focus on the chemistry and the pharmacology of pyridazine derivatives. Particularly, the 3-aminopyridazine pharmacophore allowed him to accede to an impressive variety of biological activities. Among them one can cite: antidepressant and anticonvulsant molecules; inhibitors of enzymes such as mono-amine-oxidases, phosphodiesterases and acetylcholinesterase; ligands for neuro-receptors: GABA-A receptor antagonists, serotonine 5-HT3 receptor antagonists, dopaminergic and muscarinic agonists.

Besides about 300 scientific papers and about 60 patents, Professor Wermuth is co-author or editor of several books. Particularly, the second edition of his book "The Practice of Medicinal Chemistry" was published by Academic Press in May 2003. The first edition has been translated into Japanese in 1998 and into Italian in 2000. Together with Dr P.H. Stahl, he published also the “Handbook of Pharmaceutical Salts, Properties Selection and Use” by Wiley-VCH in 2002. Professor Wermuth has been President of the Medicinal Chemistry Section of the International Union of Pure and Applied Chemistry (IUPAC) from 1988 to 1992 and from January 1998 to January 2000 was President of the IUPAC Division on Chemistry and Human Health.

156

December Meeting

The 856th Meeting Northeastern Section of the American Chem ical Society Northeastern Section of the American Chemical Society

Symposium: KINASE TARGETS Organized by the Medicinal Chemistry Section of the Northeastern Section, A merican Chemical Society

Thursday - December 9th, 2004 Holiday Inn – 1200 Beacon Street, Brookline, MA

3.00 pm Refreshments

3.15 pm Introductory Remarks Norton Peet, North Andover, MA

3.30 pm Development of non-ATP competitive MEK inhibitors David Dudley, Pfizer Global Research & Development, Ann Arbor, MI

4:30 pm The Discovery of the EGFR inhibitor IressaTM (ZD1836, gefitinib) Michael Block, Cancer Research, AstraZeneca R&D Boston, MA

5.30 pm Social Hour 6.30 pm Dinner

7.45 pm Discovery of Kinase inhibitors through a Novel approach – “Scaffold-Based Drug Discovery “TM Prabha Ibrahim, Plexxikon Inc, Berkeley, CA

THE PUBLIC IS INVITED

157

David Dudley Development of non-ATP competitive MEK inhibitors Use of the non-ATP competitive MEK inhibitors, PD98059 and PD184352 has greatly facilitated insight into the biological role of MAP kinase signaling. This talk will highlight our experience with these compounds from early screening to structural studies to the clinical setting.

David Dudley is currently a Research Fellow in Inflammation Molecular Sciences at the Ann Arbor, Michigan labs of Pfizer Global Research and Development. He obtained graduate training in Biochemistry at the University of Iowa focusing on phospholipid metabolism and it’s (then) emerging role in signal transduction. Postdoctoral training was in receptor characterization in the Department of Physiology and Biophysics at the University of Iowa. Dr. Dudley joined Parke-Davis in 1987, and continued working with receptor signaling systems, primarily those that stimulated inositol phospholipid turnover. Exposure to the compound collection and screening approaches led to the discovery of a novel angiotensin II receptor. Subsequent work in exploring the role of MAP kinases in insulin signaling led to the discovery of PD 98059 and the initial chemical matter for further MEK inhibitors. Additional work in his group has revolved around characterization of the interaction of the MEK inhibitors, and exploring the roles of other MKK family members, and signaling kinases in general, primarily for inflammation and oncology indications.

Michael Block The Discovery of the EGFR inhibitor IressaTM (ZD1836, gefitinib) Protein kinases play a key role in cellular signaling and as such they represent potentially important targets in treating a number of diseases. However, from the outset a number of key issues were apparent. Understanding the role of specific kinases in a disease setting, and the implications of inhibition, has been and remains a significant challenge. Similarly, with literally hundreds kinases all using ATP as a common co-factor, it was not clear that adequate selectivity to ensure appropriate therapeutic margins could be achieved. IressaTM (ZD1836, gefitinib) is a selective inhibitor of Epithelial Growth Factor Receptor (EGFR) kinase, that has recently been launched for the treatment of non-small cell lung cancer. The talk will outline the discovery of this molecule, illustrate that good selectivity and therapeutic margins are achievable, and discuss briefly how our understanding of the role of EGFR in cancer is developing

Michael Block began his career with a 1st class honors degree in Chemistry from the University of Edinburgh in 1982 and then moved to the University of Cambridge to study for his PhD with Professor Alan Battersby working on the synthesis of Vitamin B12 biosynthetic precursors. From 1985 to 1987 he held a Nato Postdoctoral Fellowship, working with Professor David Cane at Brown University in the USA on synthesis of labeled biosynthetic precursors of the polyether antibiotic Monensin. In 1988 he joined ICI Pharmaceuticals as a medicinal chemist and has remained with the company as it first became Zeneca and then through a merger to become AstraZeneca. He has worked in a number of different disease areas, focusing in the early part of his career on cardiovascular and antibacterial therapy, and including two years in process research and development. From 1997 to 2002 he was involved in building research at AstraZeneca in the area of diabetes and obesity. In March 2002 he moved to Boston to help lead the newly established Oncology research group, and formally took up the position of Director of Chemistry for Cancer at the AstraZeneca R&D site in Boston in January 2004.

Prabha N. Ibrahim Discovery of Kinase inhibitors through a Novel approach - “Scaffold-Based Drug Discovery “TM Plexxikon’s discovery platform is designed to discover chemical scaffolds that are broadly active on protein families sharing a common domain. Our approach uses the combination of low affinity biochemical screening and high throughput co-crystallography to identify novel scaffolds. Data from our kinase program demonstrates that in multiple instances potent and selective inhibitors with better pharmacological profile were developed with minimum iterations of chemistry. The presentation will include the approach and the discovery of kinase inhibitors.

Prabha Ibrahim is currently head of chemistry at Plexxikon Inc. Plexxikon is a drug discovery company that uses TM a novel approach, Scaffold-Based Drug Discovery , to identify drug candidates derived from proprietary scaffolds. This approach relies on the integrated efforts of structural biologists, biochemists, and computational and medicinal

158

chemists. Before joining Plexxikon in 2002, she worked at CV Therapeutics and was intimately involved in the identification and development of a number of preclinical candidates as apart of the drug discovery efforts in the cardiovascular area. She also worked at Amgen and was an integral part of the small molecule drug discovery efforts in inflammation. Dr. Ibrahim earned her PhD at the University of Victoria, Victoria, Canada, and was a Welch Foundation Fellow at Rice University, Houston, TX.

REPORT OF THE MEMBERSHIP COMMITTEE Michaeline Chen, Chair

797 “Welcome New Member” letters were sent out in 2004:

Date No. of Letters New Members Members were transferred to our Local Section March 27, 2004 144 66 48 April 24, 2004 109 51 58 August 10, 2004 145 95 50 September 17, 2004 90 52 38 October 20, 2004 163 74 89 December 21, 2004 146 57 89

159

About 60 New Members attended the monthly dinner meetings for 2004.

The purpose of the membership committee is to welcome new members, assist and support our members in need and refer them to the appropriate resources; monitor membership in our section and recommend chemists and chemical scientists for membership. I have always provided Membership Applications to non-members who attended our Monthly Dinner Meetings.

More new members are interested in employment opportunities and job information. Some are interested in the National Chemistry Week; others are interested in Gorvernmemt Relations, Hospitality and other functions.

The committee works very closely with Mrs. Karen Piper, Business Manager of The Nucleus. She supplies the labels for the new members’ roster. Our Editor of The Nucleus, Dr. Arno Heyn, placed a short note in the monthly issues of The Nucleus to invite New Members to our monthly meetings and dinners. (Due to Dr. Heyn’s passing I’ll be working with Dr.Michael Filosa for the coming year). The ACS envelopes are provided by our section secretary, Marilou Cashman.

160

Sample Welcome Letter to New Members

18 October 2004 Dear Colleague,

Congratulations on your joining the American Chemical Society and its Northeastern Section. Welcome aboard! We intend to make sure your decision to join was a wise one. We also provide you with a broad range of services and opportunities to help you personally and professionally.

I would like to invite you to be a guest of our section at the next dinner meeting--The James Flack Norris Award--on Thursday, November 11, 2004, at MIT, Cambridge, MA Walker Hall, Memorial Dr. & Ames St. Building 6 / Room 120, Eastman Laboratories.

5:30 pm : Social hour and dinner. 8:00 pm : Evening meeting: Evening Speaker: Norris Award Recipient Professor Richard N. Zare Stanford University

For dinner reservations, please contact our section secretary Marilou Cashman at 1-800-872-2054 or 1- 508-653-6329, or E-mail: [email protected], on or before the 4th November. and let her know that you are a new member or a new Local Section member. If you cannot make it this time, you may join us at one of our monthly dinner-lecture meetings of your choice in the future. Our dinner-lecture meetings are usually held on the second Thursday of each month (September through May). Social hour is at 5:30 pm, where a table of Career Services Aids and literature will be available. Dinner is at 6:30 pm., with a guest speaker to follow. The lectures are on a drop-in basis, but reservations are necessary for the dinner.

Information about our monthly meetings will be provided through The Nucleus, our monthly publication. Have you received a copy of the Nucleus? If not, please call the Business Manager of the Nucleus, Karen Piper, at 978-456-8622 or Email [email protected].

Once again, welcome to ACS and the Northeastern Section!

Sincerely yours,

Michaeline F. Chen Chair, Membership Committee Northeastern Section, ACS e-mail: [email protected] or [email protected] 529 Grove Stree Needham, Massachusetts 02492-1009

161

REPORT OF NATIONAL CHEMISTRY WEEK - 2004 Christine Jaworek-Lopes, Chair

The Tufts Dental Smile Squad was on hand for the day to demonstrate how to effectively brush teeth.

Throughout the week, volunteers from local schools and industries assisted hundreds of visitors in the week-long celebration in appreciation of chemistry in the world around us.

Christine H. Jaworek, Chair National Chemistry Week Northeastern Section, ACS

162

163

Report on NERM 2004

Morton Hoffman NESACS Representative to the NERM Steering Committee

NERM 2004 was held at the Hyatt Regency Hotel and the Riverside Convention Center in Rochester, NY, October 31-November 3, 2004. The General Chair was Richard Cobb of Kodak; the Program Chair was Joan Williams, also of Kodak. More than 700 attendees presented more than 400 papers across the spectrum of chemistry, including chemical education. Special events included a Town Hall Meeting with members of governance of the ACS and the Canadian Society of Chemists (CSC), an awards banquet, and undergraduate research poster sessions. The exposition had more than 60 exhibitors. The meeting succeeded in its design as a “mini-national-ACS meeting.”

At the end of the meeting, the NERM Steering Committee met to discuss the development of the by-laws that would come into effect when the Northeast Region is incorporated in Washington, DC, which is planned for some time in 2005. The Committee gave approval of future Northeast Regional Meetings:

July 14-17, 2005, Sacred Heart University, Fairfield, CT. October 5-7, 2006, Binghamton, NY. 2007, no NERM because the ACS National Meeting is scheduled for Boston (August). 2008, Burlington, VT.

164

REPORT OF THE NOMINATING COMMITTEE - 2004 John L. Neumeyer, Chair

The Nominating Committee was chaired by Dr. John L. Neumeyer, immediate Past-Chair of the Northeastern Section. The following are the results of the balloting for the 2004 ACS officers of the Northeastern Section. There were a total of 553 ballots counted..

NESACS ELECTION RESULTS - 2004 BALLOT

Name Votes Result Position Term

Patricia A. Mabrouk 298 Elected Chair-Elect 1 year Marietta H. Schwartz 229 Chair-Elect

James U. Piper 467 Elected Treasurer 2 years

Esther A. H. Hopkins 473 Elected Trustee 3 years

Thomas R. Gilbert 380 Elected Councilor 3 years Jean A. Fuller-Stanley 364 Elected Councilor 3 years Michael J. Hearn 358 Elected Councilor 3 years Michael Singer 355 Elected Councilor 3 years Arlene W. Light 339 Elected Alternate Councilor 3 years Pamela M. Nagafuji 335 Elected Alternate Councilor 3 years. Timothy B. Frigo 330 Elected Alternate Councilor 3 years. Susan Chiri-Buta 306 Elected Alternate Councilor 3 years. Mark Froimowitz 249 Mary A. Mahaney 227 Daniel Coughlin 225

Gary R. Weisman 321 Elected Director-at-Large 3 years Graham B. Jones 294 Elected Director-at-Large 3 years Samuel P. Kounaves 177 David W. Yesair 169

Catherine E. Costello 372 Elected Nominating Committee 1 year Ira S. Krull 249 Elected Nominating Committee 1 year Lauren K. Wolf 243 James E. Quick 136

Barry B. Snider 335 Elected Norris Award Committee 4 years J. Donald Smith 285 Elected Norris Award Committee 4 years Graham B. Jones 230 David Yue-Wei Lee 118

165

REPORT OF THE NORRIS AWARD COMMITTEE - 2004 Frederick D. Greene, Chair

The James Flack Norris Award for Outstanding Achievement in the Teaching of Chemistry is presented annually by the Northeastern Section to an educator who is both an excellent classroom teacher and whose professional activities have had a wide-ranging effect on chemical education. The committee of peers who selects the award recipient consists of elected members from the Northeastern Section and external members chosen by the committee, one of whom is the Editor of the Journal of Chemical Education.

After studying the nomination materials the committee met via conference call in late Spring to select the awardee. As is often the case, the committee was presented with a number of outstanding chemical educators who had been nominated, making the choice a difficult one.

The 2004 award was presented to Richard N. Zare, Marguerite Blake Wilbur Professor in Natural Science, Stanford University, at a dinner meeting at M.I.T. on November 11, 2004. The award address, "Chemical Fizzics: Seeing Chemistry in Action," included many demonstrations!

The citation which was presented to Professor Zare may be found immediately following this report.

Respectfully submitted, Frederick D. Greene, Chair

Committee members for 2004: - Professor Frederick Greene (ret.), Massachusetts Institute of Technology - Professor Robert Umans, Boston University - Professor Howard R. Mayne, University of New Hampshire - Professor Marietta Schwartz, University of Massachusetts Boston - Professor Jerry Mohrig, Carleton College - Professor Mary Virginia Orna, College of New Rochelle - Professor John W. Moore, University of Wisconsin, Editor, Journal of Chemical Education

Prof. Richard Zare James Flack Norris Award For Excellence in Chemical Education – Awardee 2004

166

167

Citation Presented to Professor Richard N. Zare

The Northeastern Section of the American Chemical Society confers the fifty-third

James Flack Norris Award for Outstanding Achievement in the Teaching of Chemistry on Richard N. Zare Stanford University - Stanford, California

In recognition of a career exemplifying excellence in chemical education

You are honored with this award because of the great impact you have had in enabling and inspiring students. Your passion for chemistry and education manifests itself in the classroom, with your research group, as advisor and mentor, in your writing, in interactions with colleagues at many levels, and in your public service. Your knowledge and infectious enthusiasm for chemistry and your extraordinary ability to communicate this to others have generated a host of intellectually excited students and teachers. You have notably enriched the heritage and future of chemical education.

Frederick D. Greene November 11, 2004 Jean A. Fuller-Stanley Chair, Norris Award Committee Chair, Northeastern Section

168

From the Norris Award Dinner Invitation

The Board of Directors of the Northeastern Section of the American Chemical Society requests the honour of your presence at the Dinner and Awards Ceremonies on the occasion of the presentation of The James Flack Norris Award for Outstanding Achievement in the Teaching of Chemistry to Professor Richard N. Zare Marguerite Blake Wilbur Professor in Natural Science Stanford University

on Thursday, November 11, 2004 at Walker Hall Massachusetts Institute of Technology Cambridge, Massachusetts

5:30 o'clock - Social Hour and Dinner Walker Hall Memorial Drive & Ames Street Award Ceremony and Program Building 6 / Room 120 Eastman Laboratories

R.S.V.P.

169

from the Norris Award Dinner Program:

NORTHEASTERN SECTION

of the

AMERICAN CHEMICAL SOCIETY

Presentation of the Fifty-third

JAMES FLACK NORRIS AWARD

for

Outstanding Achievement in the Teaching of Chemistry

RICHARD N. ZARE

Thursday, November eleventh Two thousand four

Massachusetts Institute of Technology Cambridge, Massachusetts

170

PROGRAM Massachusetts Institute of Technology Cambridge, MA

5:30 P.M. Social Hour 6:30 P.M. Dinner 7:45 P.M. Norris Award Ceremonies

Jean A. Fuller-Stanley Chair, Northeastern Section, Presiding

James Flack Norris Myron S. Simon Archivist, Northeastern Section

Introduction of Award Recipient Robert L. Lichter Merrimack Associates – Atlanta, GA

Presentation of Award Frederick D. Greene Chair, Norris Award Committee

Norris Award Address "Chemical Fizzics: Seeing Chemistry in Action"

Richard N. Zare Marguerite Blake Wilbur Professor in Natural Science Stanford University

Reception in honor of Professor Zare

171

JAMES FLACK NORRIS: THE MAN AND THE AWARD*

The James Flack Norris Award for Outstanding Achievement in the Teaching of Chemistry pays tribute to outstanding contributions to the field of chemical education and in so doing honors the memory of a distinguished teacher of chemistry: James Flack Norris.

The Award The Norris Award is one of the oldest national awards of the American Chemical Society and is presented annually by the Northeastern Section. The recipient is selected from an international list of nominees who have served with special distinction as teachers of chemistry at any level and whose efforts have had a wide-ranging effect on chemical education. The award has been given for a wide variety of achievements: for outstandingly effective textbooks, lecture demonstrations, or laboratory experiments, for editing the Journal of Chemical Education, for developing the Chemical Educational Material Study Project, or for new ways to teach laboratory courses in chemistry. Always, and this is of the utmost importance, the specific achievement must be coupled with dedicated teaching of chemistry at the graduate, undergraduate, or high school level. The award consists of a citation and an honorarium.

The Man James Norris was born in 1871 in Baltimore. He was the fifth of nine children and attended schools in that city and in Washington, D.C. His collegiate career started at Johns Hopkins University, from which he graduated with an A.B. degree, Phi Beta Kappa, in 1892. He was strongly attracted by the great Ira Remsen and consequently decided to carry out his graduate studies at Johns Hopkins where he investigated complex compounds of selenium and tellurium. In 1895 he obtained his Ph.D. After graduation, Professor Norris served in the Chemistry Department of M.I.T. In 1904 he then moved to the newly founded Simmons College to become its first Professor of Chemistry and to head its School of Science. He remained at Simmons until 1915 except for 1910-11 when, feeling the need for more physical chemistry, he spent a sabbatical with Fritz Haber at Karlsruhe. After one year at Vanderbilt University, Norris returned to M.I.T. where he remained for the next 24 years as an enthusiastic and successful teacher of chemistry. On February 4, 1902 he was married in Washington, D.C. to Anne Bent Chamberlin, daughter of an Army Captain. They had no children. Professor Norris died in Cambridge, Massachusetts on August 4, 1940.

In 1916 Norris was a member of the Naval Consulting Board and during World War I he served as a Lt. Colonel in the Chemical Warfare Service. After the war, he served for ten years as vice chairman and chairman of the Division of Chemistry and Chemical Technology of the National Research Council.

Although serious when the occasion called for it, the debonair Norris was known as "Sunny Jim" to a host of friends who found him a jovial companion.

His activities in the ACS were many: Chairman of the Northeastern Section in 1904 and President of the National Society in 1925 and 1926. As President of the Society, he did much to improve and clarify the finances of the society. He was also active in the National Research Council and in IUPAC, serving as vice president of the latter from 1925-28. He was an honorary member of the Rumanian Chemical Society and of the Royal Institute of Chemistry in Great Britain. In 1937, he received the gold medal of the American Institute of Chemists for "outstanding service as a teacher and as an investigator." Norris was one of the first chemists to study the structure- reactivity relationship of organic compounds on a systematic basis. Between 1912 and 1922 he authored four influential textbooks in inorganic and organic chemistry. The income from those texts, at least in part, formed the foundation of the bequest from Mrs. Norris to the Northeastern Section in 1948. The purpose of this bequest, to quote the will of Mrs. Norris, is "to keep green the memory of James Flack Norris."

The Norris Fund has grown over the years with judicious management by the Trustees of the Northeastern Section. From its income the Section sponsors two James Flack Norris Awards: the James Flack Norris Award in Physical Organic Chemistry, administered by the National ACS, and the James Flack Norris Award for Outstanding Achievement in the Teaching of Chemistry. Tonight's recipient joins a distinguished group of predecessors.

*Taken from the biographical memoir of James Flack Norris by John D. Roberts and from the biography of James Flack Norris given by Joseph Bornstein at the presentation of the James Flack Norris Award for Outstanding Achievement in the Teaching of Chemistry.

172

REPORT OF THE PROFESSIONAL RELATIONS COMMITTEE - 2004 Submitted by Truman S. Light

Truman and Arlene Light, as Councilors, attended both National Meetings at Anaheim and Philadelphia actively participating in the CEPA committee work and its subcommittees on employment. Mukund Chorghade also attended these National meetings and worked with the ACS Department of Career Services in reviewing resumes and conducting mock interviews.

Mukund Chorghade arranged an afternoon Career Services Employment Seminar that was held September 9, 2004 preceding the regular meeting of the Northeastern Section. A lecture on Resume Presentations was presented and publications of the ACS National Employment Services were distributed. These publications were also distributed at each of the monthly meetings. Also, at the monthly meetings assistance with employment was available.

The Chair-elect was assisted in planning the annual October Professional Relations meeting which included presentations of 50-year pins and the Henry Hill Award for Outstanding Local Services.

Truman (Ted) Light E-Mail: [email protected]

173

REPORT OF THE CHAIR–ELECT / PROGRAMS - 2004 Amy Tapper

As Program Chair, the Chair–Elect organized those monthly meetings of the Section (speakers, venues, etc.) that were not otherwise within the purview of the special awards committees (Esselen, Norris, Richards) and the Medicinal Chemistry Group.

January 8, 2004 – Joint Meeting with Organizational Meeting No. attended: 80 of the Boston Area Group for Informatics and Modeling (BAGIM) Speaker: Dr. Mark Murcko (Vertex Pharmaceuticals / Cambridge, MA) Title: “How Do New Technologies Influence the Drug Design Process?” Location: Harvard Faculty Club, Cambridge, MA February 12, 2004 - Joint Meeting with Younger Chemists Committee (YCC) No. attended: 72 YCC Program: Symposium & Networking Event NESACS Meeting Speaker: Dr. William Carroll, Jr. (President-Elect, ACS) Title: “Careers in Communicating Science” Location: Conte Forum / Boston College, Chestnut Hill, MA March 11, 2004 – Richards Medal No. attended: 88 Speaker: Prof. John Ross, Camille and Henry Dreyfus Professor of Chemistry emeritus, Stanford University Recipient of the Theodore William Richards Medal for Conspicuous Achievement in Chemistry Title: "Biochemical Reaction Mechanisms: Determination and Synthesis” Location: Harvard Faculty Club, Cambridge, MA April 15, 2004 - Esselen Award No. attended: 97 Speaker: Dr. James W. Jorgenson, W. R. Keenan, Jr. Distinguished Professor of Chemistry, University of North Carolina at Chapel Hill Recipient of the Gustavus J. Esselen Award for Chemistry in the Public Interest Title: “The Magic of Capillaries in Chemical Separations and Analysis” Location: Harvard Faculty Club, Cambridge, MA May 13, 2004 - Education Awards Program No. attended: 120 Speaker: Dr. Koji Nakanishi, Centennial Professor of Chemistry, Columbia University Title: “Bioorganic Studies of Natural Products” Location: NortheasternUniversity, Boston, MA Hosted by the Northeastern University Student Affiliates Chapter September 9, 2004 – Joint Meeting with Medicinal Chemistry Group No. attended: 100 Symposium Topic: New Uses for Old Drugs Speakers: Norton Peet (Aurigene Discovery Technologies, Lexington, MA) Introductory Remarks George Muller (Celgene Corporation, Warren, NJ) “The Two Faces of Thalidomide” Timothy Barberich (Sepracor, Marlboro, MA) “Evolution of the Improved Chemical Entity (ICE) Strategy” Dinner Speaker: Prof. Camille Wermuth, Université Louis Pasteur, Strasbourg, France Title: “New Leads from Old Drugs: The SOSA Approach” Location: Radisson Hotel, Woburn, MA October 14, 2004 – Hill Award & 50-Year Member Recognition No. attended: 100 Presentation of Henry A. Hill Award for Service to the Local Section to Dr. Donald O. Rickter Presentation of Certificates to 50-Year ACS Members Speaker: Francis Coppa, Esq.

174

Title: “Better Chemistry, Better Mousetrap! Patents, and What They Can Do for You”” Location: Wellesley College Club, Wellesley, MA November 11, 2003 - Norris Award No. attended: 85 Speaker: Prof. Richard N. Zare, Marguerite Blake Wilbur Professor in Natural Science, Stanford University Recipient of the James Flack Norris Award for Outstanding Achievement in Teaching Chemistry Title: “Chemical Fizzics: Seeing Chemistry in Action”” Location: Massachusetts Institute of Technology, Cambridge, MA December 9, 2004 – Joint Meeting with Medicinal Chemistry Group No. attended: 50 Symposium Topic: Kinase Targets Speakers: Norton Peet (North Andover, MA) Introductory Remarks David Dudley, Pfizer Global Research & Development, Ann Arbor, MI “Development of non-ATP competitive MEK inhibitors” Michael Block (Cancer Research / AstraZeneca R&D, Boston, MA) “The Discovery of the EGFR inhibitor IressaTM (ZD1836, gefitinib)” Dinner Speaker: Prabha Ibrahim (Plexxikon, Inc., Berkeley, CA) Title: Discovery of Kinase Inhibitors through a Novel Approach – “Scaffold-Based Drug Discovery “TM Location: Holiday Inn, Brookline, MA

REPORT OF THE PUBLIC RELATIONS COMMITTEE Steven Doherty, Chair

• All activities listed in this report were publicized extensively in The Nucleus • Information relating to all activities was provided to The Nucleus and posted on the NESACS web site; information relating to the Richards, Esselen, and Norris Awards were publicized in national journals. • Press releases relating to Section activities were written, as information was provided and upon request from officers and committee chairs; these were distributed appropriately via flyers, The Nucleus, area newspapers, Chemical & Engineering News, and area television and radio stations. . • Publicity for the programs of the local section was enhanced by targeted e-mailings to the practicing chemists at the chemical and biotechnology companies and colleges in the area. Recipients were encouraged to distribute the notices to their staff and to place them on display on public notice boards. • A photographer was present at all meetings of the Section in 2004, including the Award meetings, i.e., • March Richards Medal Award • April Esselen Award • May Education Awards • October Hill Award and 50-year Member Certificates • November Norris Award • A photographer was present at additional activities of the Section, including the Phyllis A. Brauner Memorial Lecture, the German Program, the Medicinal Chemistry programs, and National Chemistry Week activities.

175

• A strengthening of the connection between the Speakers Bureau and the Public Relations Committee has been undertaken in order to increase awareness of the Speakers Bureau and to allow for the Bureau to increase the public profile of the Section.

Monthly Meetings: Flyers were e-mailed to individuals, businesses, and colleges approximately three weeks prior to each monthly meeting; approximately 1,800+ monthly meeting flyers were e-mailed during the year with a similar number of reminders e-mailed one week prior to each meeting.

• Medicinal Chemistry Symposia: More than 600 flyers were e-mailed to publicize the three Symposia conducted by the Medicinal Chemistry Group. • 50-Year Member Recognition: Invitations to attend the October meeting as guests of the Northeastern Section were sent to 30 members celebrating their 50th year of membership. • Richards Medal Award: Approximately 200 flyers were e-mailed publicizing the Richards Medal Award Program in addition to formal invitations sent to 151 people. • Esselen Award: Approximately 200 flyers were e-mailed publicizing the Esselen Award Program in addition to formal invitations sent to ~150 people. • Hill Award: Invitations to attend the October meeting as guests of the Northeastern Section were sent to 30 individuals celebrating 50 years as ACS members and two members of the family of Henry A. Hill. The awarding of the 24th Hill Award was publicized in the “Arlington Advocate”. The local newspaper of the recipient. (Copy of Release follows.) • Norris Award: A total of 129 formal invitations to the James Flack Norris Dinner and Award Ceremony were mailed to individuals and couples representing approximately 200 people in addition to approximately 200 flyers e-mailed to individuals and companies. • Phyllis A. Brauner Memorial Lecture: 104 flyers were mailed and approximately 200 e-mailed to individuals and businesses relating to the Phyllis A. Brauner Memorial Lecture conducted at Wellesley College • ACS Short Courses: A total of 1428 flyers were mailed publicizing the two ACS Short Courses offered by the Section, as follows: April 2 478 July 30 491 September 29 459 • Career Fair: 107 letters were sent to companies soliciting their support and participation in the YCC Career Fair in addition to 72 letters sent to colleges publicizing the event. • Vendor Fair: 230 letters were mailed to companies requesting that they exhibit at the Vendor Fair. • Corporate Funding: Letters of request for donations and descriptive booklets were mailed to 127 companies seeking support for the activities of the Northeastern Section.

College and University Programs:

• German Programs: Information and applications were mailed to 95 colleges and posted on the NESACS and YCC web sites relating to the German Program planned for 2005. • Levins Prize: Publicity was provided via the web site, The Nucleus, and e-mails informing individuals in all of the graduate programs within the geographical area of the Northeastern Section to publicize the process for requesting to be considered for the Levins Prize. • Norris-Richards Summer Research Scholarships: Letters, flyers, and application forms were mailed to 95 college chemistry and/or chemistry-related departments within the geographical area of the Northeastern Section. • Grants-in-Aid: Flyers and applications were mailed to 95 college chemistry and/or chemistry- related department within the geographical area of the Northeastern Section publicizing the Section's

176

Grant-in-Aid Program to provide financial assistance to undergraduate college students to attend and participate in a National Meeting

High School Programs

• Richards Secondary School Teaching Award: This award was made known to all 381 high schools in the geographic area of the Northeastern Section to which flyers and applications were mailed. • Newell Awards: Letters were sent to 381 high schools in the Section’s geographic area including applications to participate in the competition for the Lyman Newell Award providing financial assistance to attend the NEACT Summer Conference. • Ashdown Examination: Informational letters and applications were mailed to 381 high schools and additional reminder e-mails were sent to all of the individual teachers who had participated in the Ashdown Examination for the past three years. • Connections to Chemistry: Flyers were mailed to 381 high schools publicizing the Connections to Chemistry program that was conducted in conjunction with National Chemistry Week.

REPORT OF THE PUBLIC SERVICE COMMITTEE - EDUCATION TASK FORCE - 2004 James A. Golen, Chair and William L. Dills, Jr.

Science (mostly hands-on classroom) outreach activities

We wish to report the following school activities for the 2004 year. I would also like to note that these activities were significantly reduced during 2003, due to the fact that both of us had job changes that limited our availability for this type of program.

Thu, 4/1,Wood School, Fairhaven, MA, (5th grade, 2 classes) Polymers Thu, 4/1,Wood School, Fairhaven, MA, (4th grade, 2 classes) Polymers Thu, 4/8,Rogers School, Fairhaven, MA, (5th grade, 2 classes) Polymers Thu, 4/8,Rogers School, Fairhaven, MA, (4th grade, 2 classes) Polymers Thu, 4/29,East Fairhaven School, Fairhaven, MA, (5th grade, 2 classes) Polymers Thu, 4/29,East Fairhaven School, Fairhaven, MA, (4th grade, 2 classes) Polymers Tue, 5/4,Oxford School, Fairhaven, MA, (5th grade, 2 classes) Polymers Tue, 5/4,Oxford School, Fairhaven, MA, (4th grade, 2 classes) Polymers Mon., 6/14, Cushman School (Dartmouth, MA), 5th grade (2 classes) Tie dye Mon., 6/21, Cushman School (Dartmouth, MA), 5th grade Water Rockets Tue. 7/6, Cotuit (MA) Public Library, summer program (~50 mostly 3-5th graders) Water Rockets Th., 9/30, Marion Natural History Museum (Marion, MA), (~25 mostly 2-5th graders) Polymers Fri, 11/5, Cushman School (Dartmouth), 5th grade (2 classes) Polymers

Chemical Magic Show Presentations A number of chemistry demonstration shows were done at UMass Dartmouth and also at Wellesely College. These shows were presented to roughly audiences of 300 individuals.

1. Presentation in conjunction with Dr. Dills and student helpers of Chemical Magic Shows for incoming freshmen on June 28th, July 7th, 12th, and 15th, UMass Dartmouth. 2. Chemical Magic Shows in conjunction with Dr. Dills and Dr. J.Bell at Wellesely College, Wellesely MA 10/17/04. Presentations to initiate the start of National Chemistry Week 3. Chemistry Magic Show “BOOM” presented in conjunction with Dr. Dills and UMD elves at UMass Dartmouth on 12.26/04.

177

2004 ANNUAL REPORT of the BOARD OF PUBLICATIONS Patrick Gordon, Chair

The Board of Publications (BOP) of the Northeastern Section is responsible for production of the Section’s publication, The Nucleus, as well as the Section directory and the Section’s web page (www.nesacs.org). The Board consists of three voting members, each of whom serves for a three-year term. One member is appointed by the Section chair each year. The voting members of the Board of Publications for 2004 were Patrick Gordon (chair), Marietta Schwartz and Vivian Walworth. Other NESACS members, who participated but did not vote, were Associate Editor Myron Simon, Webmaster Samuel Kounaves, Joseph Billo, and former Editor Arno Heyn, who acted as consultants to the Board of Publications. Contract personnel are the Advertising Manager, Vince Gale and the Business Manager, Karen Piper.

Marietta Schwartz and Patrick Gordon have both retired from the BOP. Newly appointed members are Mary Mahaney and Martin Idelson. Vivian Walworth will serve as Chair in 2005. Due to his teaching and research commitments, Samuel Kounaves has announced his retirement as webmaster, pending the appointment of a replacement. We thank Sam for upgrading the NESACS website and giving it a stronger appeal to visitors.

In the spring of 2003 Arno Heyn indicated that he would retire at the end of the year and that he would assist in mentoring a replacement editor. Due to illness, Arno resigned in November, 2003. Mukund Chorghade, who had been assisting Arno, served as Interim Editor for the 2004 February through May issues. Mark Spitler was appointed Editor in the spring of 2004. In October, 2004, Mark informed the BOP that he would be taking a new job that will necessitate a move to Maryland. He will be leaving the area and resigning the editorial position at the end of the year. Mike Filosa has been appointed Editor as of January 1, 2005.

In addition to long-time Associate Editor Myron Simon, new Associate Editors Nancy Simons, Ao Zhang, and Kelie Williams joined the editorial staff under the leadership of Mark Spitler. The Board welcomes the new members of the team. Vince Gale and Vivian Walworth are due thanks for recruiting this team. A number of other volunteers make up the complete staff of The Nucleus. Their responsibilities include the Calendar, Book Reviews, Feature Articles, and Proofreading. We are all indebted to the late Arno Heyn for his sagacity and continued guidance in the publication of The Nucleus.

Ten issues of The Nucleus were published during 2004: two 16-page issues, five 20-page issues, one 24- page issue, one 28-page issue, and one 32-page issue, for a total of 216 pages. Of these, 53.06 pages (24.6%) were advertising. The October issue included the fourth annual Nucleus Buyers Guide, a listing of suppliers, products, and services of interest to Section members. Advertising revenue in 2004 was $4000, or 8% lower than anticipated. With higher than expected production costs, as well as lower advertising revenue, The Nucleus stayed within budget by reducing the number of pages printed and using the volunteer services provided by the editorial staff.

178

Board of Publications Financial Report for 2004 (summarized)

budgeted actual Income: Advertising sales $50,000 $46,074

Expenses: Administration (editor, business manager, $10,250 $ 4,907 office expense) Production (printing, assembly, mailing) $51,730 $50,568 Advertising Commissions $12,500 $11,843 Total expenses $74,480 $67,318

Operating Deficiency (from Section funds) $24,480 $21,244 [This includes Section funds, Norris funds, and Nominating Committee expenses] Receivables as of December 31, 2004 were approximately $13,856.

Pages for 2003, 2004

2004 Total pp. Ads. Pp 2003 Total pp. Ads. Pp January 20 5.0 20 6.17 February 32 5.0 20 7.83 March 20 6.0 24 7.67 April 24 5.0 24 6.33 May 28 4.8 32 6.33 Summer 16 7.0 24 7.33 September 20 5.6 28 7.67 October 20 4.66 28 5.42 November 20 5.75 20 5.67 December 16 4.25 20 5.67 TOTALS 216 53.06 240 66.09 (24.6%) (27.5%) % of budgeted pp 85.7% 96.8%

NESACS Web Site Report Sam Kounaves, Tufts University

Attached are three figures indicating some of the usage info for the NESACS web site for 2004. Figure 1 shows the disk usage for the past two years. We currently have an account with NetNation that allows for 300MB of space. Extrapolating from the previous two years’ usage, we are using disk space at approx. 45MB per year. The largest users of disk space are the Nucleus pdf files, which average 2-6 MB per issue. Maintaining this rate, the current disk space allocation should suffice at least until about 2007.

Figure 2 shows a summary of the monthly visitor statistics for the NESACS web site. In terms of the more common “hits” measure, our web site has received 344,786 for 2004. This is slightly higher than the 2003 value of 315,924, but I would not consider this increase necessarily significant. The more valuable measure of “visits from unique sites” is reset each month. We had a high of 2,917 for March of 2004, compared to the high of 2,720 in October of 2003. This suggests to me that we have a reasonably stable number of visitors, which varies seasonally but otherwise little.

179

Figure 3 shows the US-domains/countries from which the hits originated. As can be seen, about 36% originated from US commercial, 11% US educational, 27% from other US network domains, 0.36 from US government/military, 8% from foreign sources, and 18% were unresolved.

Finally, Figure 4 shows which pages are accessed the most. Taking the totals for the 2nd level directories, the most visited pages are those for the Nucleus, followed by the award and seminar pages.

180

FIGURE 1 Available Disk Space: 300.00 MB, Current Disk Usage: 164.46 MB

FIGURE 2

Summary by Month

Daily Avg Monthly Totals Month Hits Files Pages Visits Sites KBytes Visits Pages Files Hits

Jan 2005 768 467 278 158 545 167080 632 1115 1871 3072 Dec 2004 1008 602 329 152 2885 2423765 4717 10221 18674 31256 Nov 2004 1065 666 273 134 2562 1779607 4048 8215 19989 31971 Oct 2004 1149 678 306 127 2654 1255479 3945 9507 21048 35632 Sep 2004 918 588 219 113 2648 1441906 3394 6578 17654 27556 Aug 2004 848 508 251 98 2014 1222016 3039 7808 15777 26312 Jul 2004 692 422 224 94 1806 1215150 2922 6955 13100 21469 Jun 2004 748 443 250 93 1926 950328 2791 7505 13294 22467 May 2004 868 533 203 101 2233 1848709 3152 6300 16531 26934 Apr 2004 1653 899 280 121 2728 1458818 3659 8416 26984 49606 Mar 2004 1275 850 289 130 2917 1058417 4053 8985 26364 39527 Feb 2004 999 701 175 100 2421 950791 2911 5094 20340 28984

Totals 15772066 39263 86699 211626 344786

181

FIGURE 3

Top 35 of 56 Total Countries

# Hits Files KBytes Country

1 11257 36.02% 6110 32.72% 764909 31.56% US Commercial 2 8341 26.69% 4711 25.23% 515112 21.25% Network 3 5748 18.39% 3971 21.26% 718362 29.64% Unresolved/Unknown 4 3288 10.52% 2044 10.95% 268666 11.08% US Educational 5 498 1.59% 360 1.93% 14419 0.59% Canada 6 269 0.86% 156 0.84% 4144 0.17% Netherlands 7 235 0.75% 155 0.83% 5493 0.23% France 8 227 0.73% 165 0.88% 1661 0.07% Non-Profit Organization 9 170 0.54% 150 0.80% 3595 0.15% United States 10 149 0.48% 126 0.67% 4140 0.17% Belgium 11 130 0.42% 93 0.50% 37686 1.55% United Kingdom 12 118 0.38% 75 0.40% 3503 0.14% Brazil 13 112 0.36% 85 0.46% 7507 0.31% Germany 14 66 0.21% 29 0.16% 1811 0.07% US Military 15 62 0.20% 45 0.24% 564 0.02% India 16 46 0.15% 32 0.17% 8686 0.36% US Government 17 39 0.12% 29 0.16% 329 0.01% Ireland 18 32 0.10% 30 0.16% 1075 0.04% Australia 19 31 0.10% 15 0.08% 762 0.03% Korea (South) 20 30 0.10% 15 0.08% 328 0.01% Colombia 21 30 0.10% 25 0.13% 285 0.01% Japan 22 28 0.09% 17 0.09% 4341 0.18% Denmark 23 25 0.08% 15 0.08% 3031 0.13% Saudi Arabia 24 24 0.08% 9 0.05% 6887 0.28% Turkey 25 21 0.07% 15 0.08% 68 0.00% Austria 26 21 0.07% 17 0.09% 400 0.02% Czech Republic 27 21 0.07% 2 0.01% 972 0.04% Slovak Republic 28 20 0.06% 19 0.10% 178 0.01% Mexico 29 20 0.06% 16 0.09% 190 0.01% Peru 30 17 0.05% 14 0.07% 43 0.00% Uruguay 31 15 0.05% 15 0.08% 72 0.00% Israel 32 15 0.05% 9 0.05% 4349 0.18% Taiwan 33 14 0.04% 14 0.07% 31 0.00% Macedonia 34 14 0.04% 8 0.04% 5244 0.22% Poland 35 14 0.04% 14 0.07% 31 0.00% Russian Federation

182

FIGURE 4

Top 35 of 756 Total URLs

# Hits KBytes URL

1 787 1.99% 8269 0.78% / 2 331 0.84% 9902 0.94% /nucleus/0012Nuc/wolfgang_dobereiner.htm 3 222 0.56% 2293 0.22% /awards/norris_richards.htm 4 188 0.48% 5831 0.55% /events/seminars.htm 5 161 0.41% 1502 0.14% /awards/awards.htm 6 161 0.41% 3206 0.30% /nucleus/nucleus.htm 7 142 0.36% 766 0.07% /who/who.htm 8 137 0.35% 1057 0.10% /jobs/employment.htm 9 127 0.32% 1049 0.10% /events/Ashdown/ashdown.htm 10 124 0.31% 746 0.07% /links/links.htm 11 106 0.27% 469 0.04% /awards/Norris-RichardsUG/instructions.htm 12 104 0.26% 1494 0.14% /business/business.htm 13 96 0.24% 1806 0.17% /business/nesacs_history.htm 14 90 0.23% 567 0.05% /awards/Norris-RichardsUG/student-form.htm 15 87 0.22% 2057 0.19% /MedChemSymp.pdf 16 87 0.22% 16810 1.59% /nucleus/htlm_files/Sept2003.htm 17 87 0.22% 553 0.05% /search.htm 18 85 0.22% 471 0.04% /contact.htm 19 85 0.22% 12776 1.21% /nucleus/pdf_files/01_Summer_Nucleus.pdf 20 76 0.19% 2466 0.23% /nucleus/obituaries.htm 21 72 0.18% 407 0.04% /awards/BruceRothBio.pdf 22 71 0.18% 12982 1.23% /nucleus/htlm_files/Summer2003.html 23 70 0.18% 23054 2.18% /nucleus/pdf_files/Dec02Nucleus.pdf 24 69 0.17% 244 0.02% /awards/Norris-RichardsUG/faculty-form.htm 25 69 0.17% 7235 0.68% /nucleus/htlm_files/December2003.htm 26 67 0.17% 1529 0.14% /business/nesacs_history/leaders.html 27 58 0.15% 1204 0.11% /business/nesacs_history/jfnorris.html 28 58 0.15% 275 0.03% /events/Ashdown/Guidelines-2004.PDF 29 57 0.14% 593 0.06% /awards/Richards/richards.htm 30 57 0.14% 21490 2.03% /nucleus/pdf_files/MAY03NucleusLR.pdf 31 52 0.13% 338 0.03% /awards/hill.htm 32 52 0.13% 753 0.07% /nucleus/02_sum_nuc/mme_lavoisier.htm 33 50 0.13% 9701 0.92% /nucleus/pdf_files/01_11_Nucleus.pdf 34 49 0.12% 735 0.07% /business/nesacs_history/dinner.html 35 49 0.12% 18580 1.76% /nucleus/pdf_files/APRIL_03_Nucleus.pdf

183

REPORT OF THE RICHARDS MEDAL COMMITTEE - 2004 Patricia A. Mabrouk, Chair

This report summarizes the work of the T. W. Richards Medal Committee for the year 2003-2004.

As is custom, the Chair of the Richards Medal Committee selected two prominent chemists from outside the Northeast Section to serve on the committee. Josef Michl (U. of Colorado at Boulder) and Kristin Bowman-James (U. Kansas) agreed to serve. Peter J. Stang, the new Editor of the Journal of the American Chemical Society, replaced former Editor, Allen J. Bard, on the Committee. Members of the Committee elected by the Northeastern Section included, Charles Kolb, Pam Mabrouk, Mary Mahaney, and Vahe Marganian.

The Chair contacted by e-mail the Chairs of the top ten research universities in the U.S. (according to C&E News) soliciting nominations and Geraldine Richmond as head of COACH. An announcement was prepared and printed in both The Nucleus and C&E News. Two nomination packages were submitted this year. Fred Greene kindly handled the arrangements for the engraving of the silver and gold medals.

John Ross, Professor Emeritus at Stanford U., was selected as the 2004 Richards Medal recipient. He received the award on Thursday evening, March 11, 2004 at a ceremony held in the Pfizer Lecture Hall in the Mallinkrodt Hall at Harvard University, following an awards dinner held at the Harvard Faculty Club.

Charles Kolb has kindly agreed to serve as the next Chair of the Richards Medal Committee.

Two points of discussion: As very few nominations were received this year, the committee discussed methods of increasing the pool of nomination packages. In the end, the Committee endorsed the idea of a canvassing committee. In addition, the suggestion was made that the committee e-mail chairs of ACS local sections and selected ACS divisions (organic, physical, analytical, inorganic, environmental, etc.) and soliciti the assistance of living Richards awardees in nominating worthy candidates.

Since this was the first time that nomination packages were submitted electronically, the Committee also discussed the adequacy of the current format of the nomination package. The Committee suggested that in the future nomination packages should consist of only one pdf file to be submitted for each candidate; and that more concrete directions be provided regarding what we want in a nominations package. The suggestion was made that the letter which should summarize the candidate's conspicuous achievements meriting receipt of the Richards medal be 3-4 pages in length and that the CV list 10-12 representative/key publications.

184

Prof. John Ross Emeritus Professor, Stanford University Recipient of Theodore William Richards Medal

185

186

REPORT OF THE SPEAKERS' BUREAU COMMITTEE - 2004 Susan Chiri-Buta, Chair

The Speaker’s committee, chaired by Alternate Councilor, Susan Buta, focused on recruiting volunteers for the James Flack Norris Speakers’ Bureau. A Call for Section Participants was published in the February 2004 Nucleus. A second short announcement was made in the December 2004 Nucleus. We also made a public appeal for volunteers at our well-attended April 2004 Section meeting. We have 11 Section members willing to participate in the Speakers’ Bureau as of December 2004. Ms. Buta met with the Public Relations Committee, NESACS Chair and Chair-elect in November to discuss our joint interests.

Speaker’s Bureau The Nucleus February 2004

The Northeastern Section of the Amer- topics in chemistry (nanotech-nology, Ican Chemical Society is renewing and combi- chem., etc), careers in revitalizing its Speaker’s Bureau. The chemistry, the greening of the chemical Section maintained the James Flack industry, water and air purification and Norris Speaker’s Bureau under the protection of our waterways (including supervision of Mary Ann Solstad from impacts from households), household 1981-1994 and Michael Dube from chemistry (including household chemicals 1994-2000. It is now being headed by and toxic substances, chemical Susan M. Buta. storage and safety at home) and the human body as a biochemistry lab The importance of an active (including simplified genetics, vita-mins speaker’s bureau should not be under- and food supplements, good chemical estimated. Chemists are the public’s practices to keep your body healthy, best resource for understanding the drugs and the body, and under-standing importance of chemistry in our every our senses). And don’t forget day lives. We know the major strides the kid’s chemistry: toys (slime, glow toward Green Chemistry, new materi-als, sticks, silly putty, etc) bubble gum, new process, etc. that our indus-tries bubble baths, and chemical demonstra- have made and we should be the tions). Though other topics are certainly bearers of our own good news. We are welcomed, it is desirable and also most able to confront the miscon- imperative to respond to the needs captions about our profession with listed above. knowledgeable answers. Consider, then, your role in edu- Our revived Speaker’s Bureau must be cating the public on chemical matters. useful and desirable to the general public. You may have an expertise in one of Speakers, theoretically, would be in better the areas above and can prepare a pres- demand if they respond to the needs of the entation. Or perhaps, you have interest community. in developing your own knowledge in one of the areas. We also encourage To understand those needs, over 50 you to partner on a topic with another towns, schools, and community groups colleague. In partnerships, even plan- were contacted in the spring and sum- ning becomes inspiring! We have mer of 2003 to glean their interests. developed training materials to help Survey results show that very popular make your participation effective, effi- interests include understanding energy cient, and most of all enjoyable. sources (coal, natural gas, nuclear, and alternative sources), the chemistry of Many companies and higher edu- automobiles, global warming, food cation institutions are supportive of chemistry (caffeine to dyes), contemporary their employee’s interest in community

187

service. If you are a business owner or news of chemistry to our area schools, manger, consider promoting participa- cities and towns, and community tion in the Speaker’s Bureau as a form organizations. Contact Marilou Cash- of company recognition and employee man by calling or e-mailing the development. A favorable public is NESACS office at 1-800-872-2054 or built on familiarity and that breeds [email protected] today! .. trust. Help NESACS spread the good

REPORT OF THE SUMMERTHING COMMITTEE - 2004 Wallace J. Gleekman, Chair

Members of the Northeastern Section, ACS had the rare opportunity to witness (after a hiatus of 86 years) the conquering march of the Boston Red Sox to (1) the 2004 American League Championship after dropping the first three games to the New York Yankees and then making an unprecedented conquest of the next four straight games to insure the pennant and (2) sweeping the first four games against the St. Louis Cardinals, the National League Champions, in an anticlimactic finish to secure the title of 2004 World Series Champions. What a season! What a finish! And the NESACS was there to view this historic phenomenon.

188

Summerthing I: May 9, 2004 Boston Red Sox vs. Kansas City Royals Sometimes bad things happen to good teams even on Mother’s Day. The Red Sox appeared poised to complete a three game sweep but it was not to be. Bill Mueller smashed a 2 run homer to give pitcher Derek Lowe an early lead but Mike Sweeny hit a 2 run double in the third to tie it up. A sellout crowd of 34,589 endured a 16-minute rain delay hoping to see the Sox make it five in a row. Going into the sixth inning, with a 2 to 2 tie, with two out and a runner on first. Lowe walked Desi Relaford and then walked David DeJesus loading the bases. Angel Berroa, the next batter, hit an infield single to third as the Royals bounced ahead 3-2. Manager Terry Francona sent in reliever Mark Malaska who promptly fell behind 3-0 on the next batter, Carlos Beltran, and then had to fire the ball down the middle to avoid another walk. Beltran hit a liner to left which cleared the bases for A 6-2 Kansas City lead. The Royals made it 7-2 in the eighth when Beltran doubled home Relaford. Manny Ramirez homered on the bottom of the eighth to make it 7-3. Matt Stinnett homered in the ninth and Johnny Damon singled home Pokey Reese for Boston’s final run. The 8-4 loss dropped the Red Sox to a one game lead over the second place New York Yankees. At the end of the fifth inning a message appeared on the scoreboard “The Red Sox welcome the Northeastern Section”.

Summerthing II: May 27, 2004 Boston Red Sox vs. Oakland Athletics Did the NESACS jinx the Red Sox? The Boston team had the best record in baseball, their pitching staff topped the American League in ERA (earned run average) and their batters averaged 6.2 runs per game at Fenway Park. In their previous nine games their fielders had committed but one error. Suddenly the Red Sox bats went silent as Mark Mulder dominated the Sox. The Boston defense collapsed as they committed two errors that led the way for six unearned runs as the A’s clobbered the Sox 15-2 before 35,438 horrified fans. It was the most runs the Sox had given up since last July 24 when Tampa Bay beat them 15-9. By the fourth inning the Sox fell to a 12-0 deficit as started Bronson Arroyo got tagged for nine runs (six earned) and seven hits and two walks in 3 1/3 innings. Pokey Reese’s error set up three unearned runs in the second inning and Kevin Youkilis’ error in the seventh led to three more unearned runs. The Red Sox scored their only runs in the sixth when Reese and Doug Mirabelli singled in Youkilis and Gabe Kapler. The only consolation for the Red Sox was that they were able to take two out of three from the A’s. The Red Sox lead over the second place Yankees shrunk to 1/2 game. During the middle of the sixth inning, the Red Sox scoreboard flashed “Fenway Park welcomes the Northeastern Section, American Chemical Society”

Summerthing III: June 23, 2004 Boston Red Sox vs. Minnesota Twins The NESACS jinx continued as the Red Sox fell to the Twins 4-2 before 35,895 disappointed fans. Derek Lowe surrendered all four runs in seven innings. Shortstop Pokey Reese sustained an injury to his hand in the top of the second and had to be removed from the game. Third baseman Mark Belhorn replaced him as Kevin Youkilis entered the game at third. The Twins loaded the bases in the first inning and scored two runs on fielder’s choices as the Sox failed to turn double plays. Minnesota scored again in the sixth when Corey Koskie doubled to center and Torii Hunter homered. Two empty bases home runs were all the Sox could muster for offense. Mark Belhorn homered in the sixth and Trot Nixon homered in the ninth. It was too little too late. The Red Sox dropped to 4 1/2 games behind the Yankees. In the middle of the seventh the scoreboard displayed the message “The Red Sox welcome the Northeastern Section ACS”.

SUMMERTHING SUMMARY On their march to the 2004 American League Championship and the 2004 World Series Championship, our cheering members of the Northeastern Section had the most unfortunate experience of witnessing

189

three Red Sox losses. This misfortune, however, did not daunt the spirit of our NESACS members who continued to support the team and cheered their wins right down to their successful finish. Meanwhile, the Red Sox have extracted a promise from the Summerthing chair: During 2005, there will not be a repeat of the 2004 NESACS record of three consecutive losses. Go Red Sox!!

190

REPORT OF THE TREASURER - 2004 James U. Piper, Treasurer

The market value of the Trust Funds at the end of 2004 was $2,274,891.55, an increase of $193,209.73 from 2003.

James U. Piper Treasurer

REPORT OF THE BOARD OF TRUSTEES - 2004 Esther A. H. Hopkins, Joseph A. Lima, Michael E. Strem

The Trustees of the Section for the year 2004 were Esther A. H. Hopkins, Michael Strem and Joseph Lima. We met with our financial consultant, Robert M. Sarly, Senior Vice President at Smith Barney,

191

Inc., held informal meetings, received reports from Smith Barney and from Piper Enterprises and discussed recommendations for the Board as to uses for the Funds in our care in keeping with the wishes of the donors of the funds.

The Trust Funds of the Northeastern Section are in three Trust Accounts and six income accounts. The Trust Accounts are (one)—the Consolidated, comprising the principal amounts of the Richards, the Norris, the Publication, the Permanent, the Hill and a portion of the Brauner trusts, (two)—the Esselen Trust, and (three)—the Levins Trust. To keep the capital ratios constant in the Consolidated Trust, capital amounts withdrawn from it are distributed to the Income accounts in the ratio of their ownership.

The Consolidated Account for 2004 had an opening portfolio value of $1,539,184.89. Withdrawals made over the year totaled $36,220.21. The adjusted opening balance was, therefore, $1,502,964.68. The closing balance was $1,742,524.09 for an increase of $239,559.41. This represents a gain of 16%. The Consolidated Trust contains money funds, common stocks, closed end funds, preferred stocks, mutual funds and corporate bonds. The current yield at year-end was 5.52% and the annualized anticipated income was $96,267.27.

The Esselen Fund, comprising money funds, mutual funds and government bonds, had an opening balance of $457,990.57. $15,195 was withdrawn for the expense of the award this year. The adjusted opening value was $442,795.57 and the closing value was $480,604.28. The Levins Fund, comprising money funds, preferred stocks, and mutual funds had an opening portfolio balance of $13,689.87. No funds were withdrawn during the year. The closing portfolio value was $13,724.81. The Brauner Trust “income account” comprised of money funds, common stock and closed end funds had an opening balance of $14,738.89. $2,613.98 was deposited from gifts to the Fund for an adjusted opening balance of $17,352.87. The closing value was $21,474.04 of which $1,878.55 was income and the remainder was Trust principal.

The Hill income account comprising money funds and closed end funds had an opening portfolio value of $8,208.42, received $1,747.93 from the prorated distribution from the Consolidated Account, and wrote checks for $1,576.00 for an adjusted value of $8.380.35. The closing value was $8,784.64. The Norris Award income account, comprising only money funds had an opening portfolio value of $12,565.81 and an adjusted value of $6,903.71 after receiving 20,418.79 from the prorated distribution and writing checks for $26,080.69. The closing portfolio value was $7,713.31. The Permanent income account, comprising money funds, common stocks and closed end funds had an opening portfolio value of $50,035.58, received $5,055.16 from the prorated distribution and wrote checks for $14,995.17 for an adjusted value of $40,095.57. The closing value of the portfolio was $48,684.36. The Publication income account, comprising money funds, common stocks and closed end funds had an opening portfolio value of $35,184.14, received $2,857.47 from the prorated distribution and wrote no checks for an adjusted value of $38,041.61. The closing value was $43,817.97. The Richards income account, comprising money funds and closed end funds had an opening value of $42,009.53, received $4,193.67 from the capital distribution, wrote checks for $12,565.82 for an adjusted value of $33,637.38. The closing value was $38,689.85.

Respectfully submitted,

The Trustees

Esther A.H. Hopkins Michael Strem Joe Lima

192

ANNUAL REPORT Northeastern Section, ACS

APPENDIX 5-A

Highlights of 2004 NESACS Meetings in Pictures

http://www.nesacs.org

193

Highlights of 2004 Northeastern Section Meetings in Pictures

James E. Phillips, Photographer

January 2004

Program Speaker – Mark Murcko Mark Murcko Jean Fuller-Stanley

Section Chair – Jean Fuller-Stanley

194

February 2004

Dr.Fuller- Stanley and Dr. William Carroll, 2004 ACS President

Arno Heyn Late Editor of The Nucleus

Arno Heyn with Myke Simon

195

March 2004

Drs. Mukund Chorghade and Pam Mabrouk Dr. and Mrs. John Ross, Richards Medal Recipient

Drs. John Ross and

George Whitesides

196

April 2004

Dr. James Jorgenson, Esselen Award Recipient, and Gustavus Esselen ,III

Dr . Jorgenson and Dr. Joe Billo

The E sselen Family

197

May 2004

Prof. Nakanishi and Colleague

Prof. Koji Nakanishi, Speaker

Aula Laud is Society: Coretta Tam, John Mauch, Marianne M cChesney, W. Cary Kilner

198

September 2004

Pam Nagafuji, MedChem Group

Vendor Table – Biotage

Prof. Camille Wermuth, the Speaker and Raj Rajur, MedChem Group

Vendor Table – Waters Corp.

Vendor Table – Mass. College of Pharmacy Dr. Dorothy Phillips Vendor Fair Committee

199

October 2004

James Golen and Frank Coppa, the Speaker

RPI Group

Drs. Mort Hoffman and Ruth Tanner

200

November 2004

Prof. Richard Zare, Norris Award Recipient and Prof. Fred Greene, Norris Award Chair

Dr. John Neumeyer, Prof. David Lemal, and David McFadden

Prof. & Mrs. Richard Zare

201

December 2004

Attendees at Medicinal Chemistry Group Symposium and NESACS Meeting

Dr. Prabha Ibrahim Program Speaker

202

ANNUAL REPORT Northeastern Section, ACS

APPENDIX 5-B

Programs: NSCRC Connections to Chemistry Nucleus Reprint: An Employment Guide for ACS Members

http://www.nesacs.org

203

The Sixth Annual Northeast Student Chemistry Research Conference

Boston University Photonics Center April 24, 2004

204

205

NSCRC 2004

Saturday,April 24, 2004

Boston University Photonics Center 8 St. Mary‘s St. Boston, MA 02215

Program Schedule:

8:30am - Poster Set-Up and Registration, Breakfast 9:00am

9:00am - Welcoming Remarks by Dr. Charles P. Casey, National ACS 9:30am President 2004

9:30am - Filiz Aslan (Boston University) 9:50am "Engineering Reduced-Size Streptavidin Mutants"

Sebastian Fritzsche (University of Leipzig) 9:50am - "Early-Late Heterobimetallic Salen Complexes as Catalysts for 10:10am Selective Epoxidation"

10:10am - Elisa Miller (Boston University) 10:30am "Chemical Dynamics of High Energy Molecules"

10:30am - Coffee Break 10:50am

Pasha Mirazimi (Boston College) 10:50am - "Development of Models for the Dynamics of Oligomeric DNA 11:10am through Solid State Nanopore Channels: Prospects for Ultrarapid DNA Sequencing"

11:10am - Mingfeng Yang (Clark University) "Mapping Early Steps of 11:30am Amyloid Formation with Computational Approaches"

11:30am - Christian Ducho (University of Hamburg) "CycloSal

206

11:50am Pronucleotides - Chemical Trojan Horses with Antiviral Activity"

11:50am - Lunch 12:30pm

12:30pm - First Poster Session (Even posters) 1:30pm

1:30pm - Second Poster Session(Odd posters) 2:30pm

Keynote Address: Dr. Stephen Lippard of MIT: 2:30pm - "New Fluorescent Sensors to Study Biochemical Zinc and Nitric 3:30pm Oxide and to Monitor Mercury in the Environment"

3:30pm - Awards Presentation 3:50pm

3:50pm - Closing Remarks, Poster Take-Down 4:00pm

This conference is being sponsored by:

Posters 2004

1. Biomimetic Iron Complexes with Amide-Containing Pentadentate Macrocyclic Ligands Ivan V. Korendovych, Olga P. Kryatova, Elena V. Rybak-Akimova Tufts University, 62 Talbot Ave., Medford, MA 02155

2. Exploring the Properties of Phosphido-borates as Ligands in Transition Metal Chemistry Franz Dornhaus, Matthias Wagner Institute for Inorganic Chemistry, Marie-Curie Strasse 11, 60439 Frankfurt/Main, Germany

3. In Search of a Homogeneous Gold Catalyst with Long-term Stability Jan P. Weyrauch, A. Stephen K. Hashmi University of Stuttgart, Pfaffenwaldring 55, D-70569 Stuttgart

4. Modeling the Zn2+ Coordination Site of Zinc Metalloenzymes Using Peptide Phage Display Kristin Felice, Marilena F. Hall Stonehill College, 320 Washington St. Box #193 N. Easton, MA 02357

207

5. Simultaneous Removal of SOx and NOx Using a Wet Flue Gas Cleaning Processes Liliang Zhang, Yuegang Zuo University of Massachusetts Dartmouth, 285 Old Westport Road, North Dartmouth, MA 02747

6. Vitisin A: Synthesis, Isolation by Chromatography Michael Schwarz, Peter Quast, Dietrich von Baer, Peter Winterhalter Technical Universitiy of Braunschweig, Braunschweig, Germany

7. GC-MS Evaluation of Phenolic Antioxidants in Human Plasma Kai Zhang, Yuegang Zuo University of Massachusetts - Dartmouth, North Dartmouth, MA, 02747

8. Following Nature's Lead - Methane Oxidation by a Dinuclear, Non-heme Iron Catalyst Trina L Foster, John P Caradonna Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

9. Synthesis and Solvolysis of Trifluoromethyl Substituted Gamma Silyl Systems Shaina Byrne, Sean Arsenault Stonehill College, 320 Washington Street, Easton, MA 02357

10. Synthesis, Purification, and Characterization of Glutathione Dialkylester Conjugates with 3-Methyleneoxindole Karen L. DeBalsi , Edward J. Brush Bridgewater State College, Bridgewater, MA 02325

11. Slicing and Dicing RNA: First Observation of a Deuterium Kinetic Isotope Effect on Hydroxyl Radical Cleavage of RNA Timothy Gay, Alison Moore, Thomas Tullius Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

12. Kinetics of Oxygen Binding and Activation by Dinuclear Non-heme Iron(II) Complexes Sergey V. Kryatov, Elena V. Rybak-Akimova Tufts University, Medford, MA 02155

13. Chemical Dynamics of High Energy Molecules. Elisa Miller, Amy Mullin Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

14. Swelleable Poly(hydroxyethylmethacrylate) Microspheres for pH and Metal Ion Sensing George K. Mwangi, W. R Seitz University of New Hampshire, 14 Forest Park, Durham, NH. 0382

15. Investigation into the Concentration of Antibiotics in Natural and Treated Water Systems Erin Dieckman, Stephen Theberge Merrimack College, 315 turnpike St. North Andover, MA, 01845

16. Molecular Dynamics Simulation on Human Transthyretin and it Variants Mingfeng Yang, Ming Lei, Shuanghong Huo Clark University, 950 Main St, Worcester, MA

17. Mechanistic Mutant Studies of Phenylalanine Hydroxylase SuzAnn Hertzler, S.Datta, E.I. Solomon, J.P. Caradonna

208

Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

18. Investigation of the Acidity of Phosphorus(III) Ligands Using UV-vis Spectroscopy C. Moura, A.L. Fernandez, B. Gregory, S. Salamone Merrimack College, 315 turnpike St. North Andover, MA, 01845

19. Engineering Reduced-Sized Streptavidin Mutants Filiz Aslan, Yong Yu, Zhiping Weng, Scott Mohr, Charles Cantor Boston University, 36 Cummington St, Boston, MA, 02215

20. CycloSal Pronucleotides - Chemical Trojan Horses with Antiviral Activity Christian Ducho, Ulf Goerbig, Jan Balzarini, Chris Meier University of Hamburg, Institute of Organic Chemistry, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany

21. Total Syntheses of the Oximidines, Salicylate Enamide Antitumor Agents Xiang Wang, John A. Porco, Jr. Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

22. Development of Models for the Dynamics of Oligomeric DNA through Solid State Nanopore Channels: prospects for Ultrarapid DNA Sequencing Pasha Mirazimi, Udayan Mohanty Boston College, 140 Commonwealth Avenue Chesnut Hill, MA 02467

23. Direct Coupling of TLC with Newly Designed High-Throughput, HP MALDI-FTMS for the Analysis of Glycolipids from Biological Sources Vera B. Ivleva Boston University, Medical Campus, Boston, MA, 02118

24. Early-Late Heterobimetallic Salen Complexes as Catalysts for Selective Epoxidation D.C. Sebastian Fritzsche, Evamarie Hey-Hawkins University of Leipzig, Johannisallee 29, 04103 Leipzig, Germany

25. Formation of Dimers That Contain Unbridged W(IV)/W(IV) Double Bonds Lourdes Pia H. Lopez, Richard R. Schrock MIT, 77 Massachusetts Avenue, Cambridge, MA, 02138

26. Separation of Rabbit-liver metallothionein isoforms high performance capillary electrophoresis. Oliver E. Okumba-Arigi,, John H Beattie University of New Hampshire, 23 College Rd, Parsons, Durham NH. 03824

27. Versatile Fluorescent Probes of Protein Kinase Activity Melissa D. Shults, Barbara Imperiali MIT, 77 Massachusetts Ave, Cambridge, MA, 02139

28. Individual Cell Migration Analysis Using Fiber-Optic Bundles Christopher Dicesare, David R. Walt Tuft's University, 62 Talbot Ave., Medford, MA 02155

29. Caged Phosphoserine Peptides and Proteins Deborah M. Rothman, Barbara Imperiali MIT, 77 Massachusetts Ave, Cambridge, MA, 02139

209

30. Role of Mouse CYP2E(-I-) in the o-hydroxylation of p-nitrophenol: a Comparison of Hepatic Activities in CYP2E(-I-) and Wild-Type Mice K.K. Wolf, S.G. Wood, J.L. Bement, P.R. Sinclair, S.A. Wrighton, E.H. Jeffery, F.J. Gonzalez, J.F. Sinclair Dartmouth Medical School, Hanover, NH 03756

31. Shuttling Electrons: Understanding the Redox Properties of Archaeoglobus fulgidus Thioredoxin Reductase Sarah E. Chobot, Sean J. Elliott Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

32. To Rearrange or Not to Rearrange? That is the Question! A study of the Synthesis and Possible Rearrangement of Pyrrol-2-ones Nathan Maugel, Cynthia McGowan Merrimack College, 315 Turnpike St. N. Andover, MA 01845

33. II-VI semiconductor fullerenic clusters A. Burnin, J. J. BelBruno Dartmouth College, Burke 6128, Hanover, NH, 03755

34. Green Chemistry Using Non-Covalent Derivatization, The Manipulation of Physical Properties of Materials By Using Intermolecular Interactions Michele Turner, Amy S. Cannon, John C.Warner University of Massachusetts-Boston, 100 Morrissey Blvd., Boston, MA, 02125

35. The Effect of a Single-Nucleoside Gap in DNA on Cyclization Kinetics Truc T. Diep, Thomas D. Tullius Boston University, 590 Commonwelath Avenue, Boston, MA, 02215

36. Individual Cell Migration Analysis Using Fiber-Optic Bundles Christoher Dicesare, David R. Walt Tuft's University, 62 Talbot Ave., Medford, MA 02155

37. Conversion of D-galactopyranoside to D-talopyranoside Renato A. Bauer, Louis J. Liotta Stonehill College, 320 Washington Street, Easton, MA 02357

38. Spectroscopic and Kinetic Studies of PKU Inducing Mutants of Phenylalanine Hydroxylase Supratim Datta, Tara Acharya, Hau Le and John P. Caradonna Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

39. Chemical Approaches to Understand and Modulate DNA Polymerase Functions H. Martin Mueller and Andreas Marx University of Bonn, Gerhard-Domagk-Str.1, 53121 Bonn, Germany

40. Experimental and Theoretical Study of the Internal Rotation in Trimethyl-Tin-Chloride Melanie Schnell, Deike Banser, Jens-Uwe Grabow Institut fuer Physikalische Chemie, Callinstrasse 3-3a, D-30167

41. Dianions of Mercaptocarboxylic Acids as Bifunctional Ligands in Heterometallic Complexes Ulrike Helmstedt, Evamarie Hey-Hawkins

210

University of Leipzig, Johannisallee 29, 04103 Leipzig, Germany

42. Oligofunctional tris(1-pyrazolyl)borates and Cyclopentadienyl-scorpionate Hybrid Ligands Susanne Bieller, Fan Zhang, Hans-Wolfram Lerner, Matthias Wagner Institute for Inorganic Chemistry, Frankfurt, Germany

43. AWACSS - Automated Water Analyser Computer Supported System Jens Tschmelak, Guenther Proll, Guenter Gauglitz University of Tuebingen, IPTC, Auf der Morgenstelle 8, D - 72076

44. Field-Effect Transistors: A Self-Assembly Approach Jan Mueller, Andreas Terfort University of Hamburg, Martin-Luther-King Platz 6 20146 Hamburg Germany

45. Synthesis of Aminoglycoside Mimetics Using Orthogonally Protected Sugar Diamino Acid Building Blocks Frank Sicherl, Valentin Wittmann University of Konstanz, Fachbereich Chemie, Konstanz, Germany

46. Synthesis of a Fully Solvated Molybdenyl Complex with the [Mo2(µ-O)2O2]2+ Core Travis R. Pribusauskas, Steven C. Haefner Bridgewater State College, Bridgewater, MA 02325

47. Spectral Characterization and Origin Classification of Natural Waters by Multidimensional Fluorescence Kerin E. Clow, Gregory J. Hall, Hao Chen, Jonathan E. Kenny Tufts University, 62 Talbot Avenue, Somerville, MA

48. Total Synthesis of Guanacastepene A through a [4+2+2] Homo Diels-Alder Approach Alexandra E. Hours, John K. Snyder Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

49. Solid State NMR and the Thermal Solid State Polymerization of 2,4-hexadiyne-1,6-bis- (p-toluenesulfonate) Jeffrey M. Njus, Daniel J. Sandman University of Massachusetts Lowell

50. Modeling Important Atmospheric Nonadiabatic Charge Transfer Reactions and Collision Induced Electronic Transitions L. Chen, D.F. Coker, H. Dothe Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

51. Heavy Metal Pollution in Sediment of the Salisbury Plain River Lower Eric Curry, Drainage Basin, Jordan Bethoney, Cielito D. King Bridgewater State College, Bridgewater, MA 02325

52. Total Synthesis of Cystothiazole A and B Jian Shao, James Panek Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

53. Application of Chiral Anthracenes as Templates in the Synthesis of Pyrrolizidine, Indolizidine and Related Alkaloidal Core Ring Systems Wanlin Yan, John K. Snyder

211

Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

54. Initial Design and Implementation of a Cryogenic Preamplifier for FTICRMS Raman Mathur Boston University, School of Medicine, Boston, MA, 02138

55. Designing High School Chemistry Peer Led Workshops Arlin Vargas, Morton Z. Hoffman Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

56. Synthesis of 1,4,5-Trisubstituted 1,2,3-Triazoles by Copper-Catalyzed Cycloaddition- Coupling of Azides and Terminal Alkynes Jamie Ryan, Baudoin Gerard, Aaron Beeler, John A. Porco Jr. Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

57. Computer simulated single amino acid substitution in copper amine oxidases and its impact on catalytic mechanism Aaron Gregory Schmidt, Michael Flaherty Emmanuel College 400 The Fenway, Boston MA 02115

58. Peer-Led Team Learning: An Innovative Pedagogical Approach for Teaching General Chemistry Meghan Clancy, Dr. Morton Hoffman Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

59. Mild and Selective Synthetic Methods Sha Lou Boston University, 590 Commowealth Avenue, Boston, MA 02215

60. Molecular dynamics studies of the PCAf bromodomain in complex with HIV-1 Tat peptide, and with Acetylated Lysine Haijun Yang, Ming Lei, MingFeng Yang, Shuanghong Huo Clark University, 950 Main st, Worcester, Ma 01610

61. Synthesis of Azaphilone Natural Products and Related Molecules Employing Cylcoisomerization of o-Alkynylbenzaldehydes Andrew Germain, Jianglong Zhu, Nicholas Grigoriadis, John A. Porco, Jr. Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

62. Improved Algorithms for Interpretation of High Resolution Mass Spectra Parminder Kaur Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

63. Synthesis of New Chiral Camphor-based 1,4 Amino Alcohols. Urvi Sheth, Vesa Nevalainen University of Masachusetts at Dartmouth, Dartmouth, MA, 02740

64. Iron Detoxification Properties of the Ferritin-like Dps Protein from Listeria Innocua Meihong Su, Emilia Chiancone, N. Dennis Chasteen University of New Hampshire, Durham, 03824 NH

65. Increase of the Activity of Candida antarctica lipase B upon Entrapment in PEG-PEI Block Copolymer Micelles Benjamin Malte Rossbach, Asier Galan, Ralf Weberskirch

212

Lehrstuhl fuer Makromolekulare Stoffe, Garching, Germany

66. The Synthesis of Aplha-Carbolines via Intramolecular Inverse Electron Demand Diels- Alder Chemistry Sie-Mun Lo, Phil Roveto, John K. Snyder Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

67. New Approaches to Small Molecule Activation Using Three-Coordinate Early Transition Metal Complexes Joshua S. Figueroa, Arjun Mendiratta, Emma L. Sceats, Christopher R. Clough, Christopher C. Cummins MIT, 77 Massachusetts Ave.,Cambridge, MA, 02139

68. Synthesis and catalytic properties of novel iron(II) complexes of pyridine-containing macrocycles bearing an aminopropyl pendant arm Sonia Taktak, Aida M. Herrera, Elena V. Rybak-Akimova Tuft's University, 62 Talbot Avenue, Sommerville, MA

69. Reflection and Transmission Diffraction Measurements of Phonon Polaritons in LiNbO3 and BaTiO3 Eric R. Statz, Kenji Katayama, David W. Ward, Keith A. Nelson MIT, 77 Massachussets Ave., Cambridge, MA, 02143

70. Synthesis of Novel Bio-active Indolocarbazoles Sudipta Roy, Alan Eastman, Gordon W. Gribble Dartmouth College, Hanover, NH, 03755

71. Chiral Anthracene Based Diels-Alder/Retro Diels-Alder Strategy for Butenolide and lactam Synthesis Qian Yuan, John K. Snyder Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

72. Preparation of Polymeric Nanostructures Using Electrochemical Dip-Pen Nanolithography Shaun Filocamo, Ben Maynor, Jie Liu, Chad Immoos, and Mark Grinstaff Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

73. New, Homochiral Anthrones as Enantioselective Templates for the Synthesis of Butenolides and Lactams in a Diels-Alder/Retro-Diels-Alder Sequence Xiang, Liu , John K. Snyder Boston University, 590 Commonwealth Avenue, Boston, MA 02215

74. Study Towards the Synthesis of the Antitumor Agent (-)-Zampanolide Jia Yi Yuan, Dawn M. Troast, John A. Porco, Jr. Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

75. Differentiation of Alpha Versus Beta-aspartic Acid Residues in Peptides by Electron Capture Dissociation Fourier-transform Mass Spectrometry Jason J. Cournoyer, Jason L. Pittman, Vera B. Ivelva, Lucy Waskell, Peter B. O'Connor Boston University, 715 Albany Street, R-R806, Boston, MA 02118

76. Synthesis of Rocaglamide Natural Products Baudouin Gerard, Guilford Jones, and John A. Porco, Jr. Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

213

77. Biodendritic Amphiphiles Nathanael Luman, Mark Grinstaff Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

78. Kinetics of Phenyl Radical Addition to Butadiene Using Quantum Chemistry Huzeifa Ismail, Bryan M. Wong, William H. Green, Jr. MIT, 25 Ames Street, Cambridge, MA 02139

79. Thermal Control of Competitive Adsorption and Desorption at a Solid Surface Kimberly Dolan, John Beauregard Assumption College, 500 Salisbury St, Wocester, MA 01609

80. [4+2]-Annulations Toward the Stereoselective Synthesis of Alkaloid 205B Leland L. Johnson Jr., James Panek Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

81. Computational Studies at the Semi-empirical Level on Dimethylsilanes and the Carbon Analogues Natasha Soodoo, Jean Fuller-Stanley Wellesley College, 106 Central Street, Wellesley, MA 02481

82. Synthesis and in vivo Mutational Properties of the Guanine Oxidation-Nitration Product 5-Guanidino-4-nitroimidazole William L. Neeley, Paul T. Henderson, James C. Delaney, and John M. Essigmann MIT, Cambridge,MA 02139

83. Synthesis of Naphthyridine Library by [2+2+2] Cyclocondensation Ya Zhou, John K. Snyder Boston University, 590 Commonwealth Avenue, Boston, MA, 02215

Awards 2004 Best Oral Presentation ($100, sponsored by Strem Chemicals, Inc.):

Christian Ducho (University of Hamburg) "CycloSal Pronucleotides - Chemical Trojan Horses with Antiviral Activity"

214

Best Poster Presentations ($100 each, sponsored by Genzyme):

Supratim Datta (Boston University) "Spectroscopic and Kinetic Studies of PKU Inducing Mutants of Phenylalanine Hydroxylase"

Christopher Dicesare (Tufts University) "Individual Cell Migration Analysis Using Fiber-Optic Bundles"

Jamie Ryan (Boston University) "Synthesis of 1,4,5-Trisubstituted 1,2,3-Triazoles by Copper-Catalyzed Cycloaddition-Coupling of Azides and Terminal Alkynes"

215

Poster Book Prizes (sponsored by Kluwer):

Lourdes Pia H. Lopez (MIT) "Formation of Dimers That Contain Unbridged W(IV)/W(IV) Double Bonds"

Nathan Maugel (Merrimack College) "To Rearrange or Not to Rearrange? That is the Question! A study of the Synthesis and Possible Rearrangement of Pyrrol-2-ones"

William Neeley (MIT) "Synthesis and in vivo Mutational Properties of the Guanine Oxidation-Nitration Product 5-Guanidino-4-nitroimidazole"

Aaron Gregory Schmidt (Emmanuel College) "Computer simulated single amino acid substitution in copper amine oxidases and its impact on catalytic mechanism"

Melanie Schnell (University of Hannover) "Experimental and Theoretical Study of the Internal Rotation in Trimethyl-Tin-Chloride"

216

Frank Sischerl (University of Konstanz) "Synthesis of Aminoglycoside Mimetics Using Orthogonally Protected Sugar Diamino Acid Building Blocks"

Brauner Undergraduate Book Award (sponsored by the NESACS Education Committee):

Elisa Miller (Boston University) "Chemical Dynamics of High Energy Molecules"

217

218

Complete Program: Con nections to Chemistry

Connections to Chemistry

Burlington High School Burlington, Massachusetts October 13, 2004

219

Sponsored by the Northeastern Section of the American Chemical Society The American Chemical Society and The Northeastern Section

The American Chemical Society (ACS) is the largest scientific organization in the world that is devoted to a single discipline –chemistry– with more than 160,000 members at all degree levels. Among its members are teachers that span the entire spectrum of chemical education: high schools, two- and four-year colleges, and research universities. The specific interests of the members of the ACS are reflected in the activities of the 34 technical divisions, such as the divisions of Organic Chemistry, Biological Chemistry, Computers in Chemistry, Chemical Education, and the History of Chemistry.

The membership in the Division of Chemical Education (DivCHED) is open to anyone who has an interest in chemical education, including those who teach chemistry in high schools, community colleges, 4-year colleges and universities; membership also includes chemists in industry, government, and foundations. DivCHED publishes the Journal of Chemical Education, which is a monthly journal for all teachers of chemistry, from K–16 and beyond. In addition, DivCHED offers programs for teachers and students to further enhance the learning of chemistry and the future of the profession. For more information, visit the American Chemical Society website at http://www.acs.org.

The ACS has more than 180 local sections of which the Northeastern Section (NESACS) is one of the largest, with almost 6,000 members, encompassing Eastern Massachusetts and New Hampshire. NESACS holds monthly meetings and offers a wide range of technical and social programs for younger chemists, retirees, and all those in between. The Education Committee of NESACS sponsors programs for high school and college students, and programs for chemistry teachers and others who have an interest in chemical education. For more information, visit the NESACS website at http://www.nesacs.org.

220

Program Schedule

Connections to Chemistry

October 13, 2004 3:30 – 4:00 p.m. Registration and Refreshments Main Lobby, Burlington High School

4:00 – 4:25 p.m. Welcome, Overview, and Review of the Sessions (Auditorium) Ruth Tanner, Chair, Education Committee, NESACS Professor of Chemistry, University of Massachusetts Lowell

Morton Hoffman, Chair-Elect, Division of Chemical Education, ACS Professor or Chemistry, Boston University

Steve Lantos, Chair, High School Education Committee, NESACS Chemistry Teacher, Brookline (MA) High School

4:30 – 6:10 p.m. Four Simultaneous Workshops in Two Sessions: Session I: 4:30 – 5:15 Session II: 5:25 – 6:10

Workshop A: Turn Them Into Writers (Room 179) Carolyn Collins Petersen, Science Writer and VP of Loch Ness Productions

Workshop B: The Real CSI Lab (Room (Room 176) William Hebard, Forensic Chemist, Massachusetts State Police Crime Laboratory

Workshop C: Cows Eat Grass; People eat Pasta (Room 172) Edwin Jahngen, Biochemist, Department of Chemistry, University of Massachusetts Lowell

Workshop D: Bonding and Molecular Graphics (Room 177) Frank Gorga, Department of Chemical Sciences, Bridgewater State College (A two session workshop, 4:30 - 6:10 PM)

6:15 – 6:55 p.m. Dinner (High School Cafeteria)

7:00 –7:45 p.m. Address (Auditorium) Vampires, Rockets and the Hot Zone-Confronting Emerging Infectious Diseases Mark Klempner, M.D., Director of the National Biocontainment Laboratories (National Center for Emerging Infectious Diseases and Biodefense) and Associate Provost of Research at Boston University’s Medical Campus

221

Keynote Address

Mark Klempner, M.D. Dr. Klempner is the Conrad Wesselhoeft Professor of Medicine, an expert in the study and prevention of infectious diseases, and Associate Provost for Research at Boston University's Medical Campus and Director of the National Biocontainment Laboratories at Boston University. These laboratories, funded by a $128 million grant from the National Institutes of Health, were created in order to study and protect the American public against emerging infectious diseases and agents of bioterror. Dr. Klempner is also Associate Editor of the New England Journal of Medicine. Dr. Klempner’s research interests have focused on the molecular aspects of how infectious agents cause human disease. In recent years, he has spearheaded several studies on Lyme Disease -- ranging from how the bacteria invades the human body to vaccine development and treatment options. Grants from the NIH and NASA are funding another research focus of Dr. Klempner's -- a design for new technologies that will have the ability to quickly fingerprint different kinds of micro-organisms including deadly anthrax spores. His research has been continuously funded from the NIH and NASA for over 24 years.

The author of more than 260 scientific publications and contributor to 16 books, Dr. Klempner was the recipient of the prestigious Squibb and Abbott Awards from the Infectious Diseases Society of America, has been repeatedly cited as one of the Best Doctors in America, and was elected to the American Society for Clinical Investigation and the Association of American Physicians.

Dr. Klempner attended Tulane University and Cornell University Medical College where he was honored by both institutions for his academic achievements. After completing his internal medicine internship and residency at the Massachusetts General Hospital, he trained in both clinical and research aspects of infectious diseases at the National Institute of Health. Dr. Klempner spent the next 20 years at Tufts New England Medical Center where he served as the Endicott Professor of Medicine, Vice Chairman for Scientific Affairs and Chairman of the New England Medical Center Research Council.

Dr. Klempner’s address, Vampires, Rockets and the Hot Zone-Confronting Emerging Infectious Diseases, will discuss what it takes to become a successful microbial invader (pathogen).

222

National Chemistry Week

Celebrate National Chemistry Week October 17-23, 2004

For more information on the National Chemistry Week programs for the Northeastern Section, go to .

223

Workshops

224

Workshop A: Turn Them Into Writers!

Carolyn Collins Petersen, Science Writer and VP of Loch Ness Productions

Our classrooms and labs are filled with nearly everything we need to tell good science stories! We have science procedures and outcomes, and budding storytellers to help report what we've done. But, we also need some basic storytelling tools to help present complex science to the general public.

How can we learn to tell good science stories? By doing as the science journalists do. In order to report on a hot new discovery or technological breakthrough, science writers use a combination of good storytelling instincts, an understanding of the sciences they're presenting, and some basic journalistic tools.

Writing a story about your science for someone else to read is an excellent way to reinforce your own knowledge. This workshop, conducted by a working science writer, will take you on a journey to find the science journalist within you, and give you some ways to help your students do the same.

We will first learn the basics of journalism -- the building blocks of stories. This means understanding the Who, What, When, Where, Why, and How for an example story, as well as the time and space constraints that shape all news stories. We'll examine the basic tool of journalism -- the inverted pyramid form -- and how to use it to shape a good science story.

Participants will take a press release and write a story that would work well in a magazine, newspaper, radio or TV news broadcast, or an online Web blog or news site. Then everyone will share their stories with fellow participants. Finally we will discuss ways to incorporate this exercise into our classroom activities. Bring your imagination and writing talent!

RESOURCES

The following websites are good sources for science news and press releases, and you are invited to browse them for ideas and methods you can use. The workshop will borrow liberally from one or two of these sources.

American Chemical Society: http://www.chemistry.org/portal/a/c/s/1/home.html American Press Institute Journalist's Toolbox for Science Writers http://www.americanpressinstitute.org/content/4062.cfm Science News Online http://www.sciencenews.org/ Astrochem.org http://www.astrochemistry.org/ Communicating Chemistry http://www.soton.ac.uk/~pw/teach/cheminfo/comchem/writing/writing.html EurekAlert.org. http://www.eurekalert.org EurekAlert is primarily aimed at journalists seeking material for news stories. There is a private area restricted to working journalists, but the public areas are open to all. Stories are sorted by discipline.

225

Workshop B: Using Science to Identify Blood at a Crime Scene

William Hebard, Massachusetts State Police Crime Laboratory

This workshop hopes to give teachers a platform from which several basic Chemistry principles can be explained.

• Diffusion of molecules through a medium • Identification of matter by it’s chemical and physical properties • Change of physical properties of a substance after it has undergone a chemical reaction • Antigen-antibody lock and key mechanism

Forensic chemists need to identify unknown stains before submitted these exhibits for DNA analysis. This workshop explains how a chemist would pick and then identify the correct stains, often from a chaotic scene, as human blood.

Step 1: Locate and screen the appropriate stain. Using a chemical reaction we will identify which stain is potentially human blood.

Step 2: Choose the most evidentially significant stain for collection. Using the Science of Blood Spatter interpretation, we will discuss which stain would give the most information to help investigators in this crime scene.

Step 3: Positively identify our samples. Using a kit from Carolina Educational Company we will explore how scientists have used the body’s immune response system to positively identify samples as human blood.

226

Workshop C: Cows Eat Grass; People

Eat Pasta?

Professor Edwin Jahngen, Department of Chemistry, UMass Lowell Pamela Jahngen-Provencal, Francis College of Engineering, UMass Lowell

Diets abound! People are constantly trying to loose weight with this regime or that scheme. [Unfortunately most of these do not include reducing food intake and exercise!!] Currently low carbohydrate diets (such as the Atkins Diet) are at the top of the diets of choice for loosing weight. Why would that be? For that matter what are carbohydrates, how do they differ from simple sugars and why do some mammals, (mainly herbivores), enzymatically process cellulose, (grass), while others (carnivores), can only process starch, (pasta).

This workshop will include a brief introduction regarding the 3-D structures of carbohydrates. It will continue with three experiments that address the differences between simple sugars and carbohydrates, reducing sugars and the enzymatic reaction that degrade Starch and not Cellulose to useable fuels for a human “bioreactor”.

Following a brief discussion of the structures of sugars the first experiment will be to actually determine if a given sugar has the ability to donate an electron to another molecule. These actively donating sugars are reducing sugars. The experiment involves the classic Benedict’s test for reducing sugars. In this protocol cupric ion is reduced to cuprous and a color change is noted for reducing sugars. We will test mono- di- and polysaccharides and demonstrate that under hydrolytic conditions, polysaccharides and non-reducing disaccharides may become reducing sugars.

In the second experiment the physical properties of the polysaccharide pectin will be investigated. Pectin solution will form hydrogels when an acid and/or sugar are added. The decrease in pH by the addition causes a self- assembly of the carbohydrate chains of the Pectin forming a polymer network which traps water. The gel formed by decreasing the pH may be made rigid by the addition of sugars, which now dehydrates the gel leaving a more plastic polymer. By varying the amounts of acid and sugar different properties of the Pectin may be observed and documented.

The final experiment involves the enzymatic conversion of starch into maltose using the enzyme amylase. Initially the starch solution may be examined by its ability to change an iodine solution to deep purple. As the enzymatic conversion proceeds the polymeric starch that is a hydrogel like the Pectin described above begins to be hydrolyzed into smaller chains and ultimately to a disaccharide. The conversion to the disaccharide maltose may be observed by using the Benedicts test for reducing sugars. Additionally, the iodine test may be applied to examine the presence of unhydrolyzed starch.

227

Workshop D: Bonding and Molecular Graphics

Frank R. Gorga, Ph.D., Dept. of Chemical Sciences, Bridgewater, MA 02325

Do your students have trouble visualizing molecules in three-dimensions? If so, this workshop is for you.

Freely available software (RasMol and WebLabViewer) for personal computers allows the easy display and manipulation of three-dimensional molecular models on the screen. Static pictures prepared with these applications can be copied and pasted into word processing and PowerPoint documents. Other software (CHIME; also freely available) allows one to prepare web pages that contain “live” three-dimensional models that a user can manipulate. Participants will be introduced to these programs, their use in preparing teaching materials.

If one does not have the time or inclination to prepare one’s own material, there are many web-based resources that contain three-dimensional representations of molecules, large and small and that represent useful tools in the teaching of both biology and chemistry. Examples of this type of resource and web sites that maintain indices of these resources will be shown.

Copies of all materials and files used in this workshop are available at http://webhost.bridgew.edu/fgorga/ctc04.

Also, see http://webhost.bridgew.edu/CityLab for biotechnology education programs for both students and teachers offered at BSC-CityLab.

228

Thank You

We gratefully acknowledge the contributions of the following organizations and individuals for their support of the 2004 Connections to Chemistry program. We would like to extend our special thanks to Burlington High School for hosting this program.

Program Conference Committee

Ruth Tanner, Chair, Education Committee, NESACS; University of Massachusetts Lowell Morton Hoffman, Chair-Elect, Division of Chemical Education, ACS; Boston University Susan Buta, Chair, Speakers Bureau, NESACS Steve Lantos, Chemistry Faculty, Brookline (MA) High School Jerusha Vogel, Chemistry Faculty, Lexington (MA) High School

Planning and Program Associates

Material Assistance

Publicity Support

New England Association of Chemistry Teachers (NEACT) Massachusetts Association of Science Supervisors (MASS) Massachusetts Association of Science Teachers (MAST) The Nucleus (NESACS)

229

Registered Schools

Massachusetts Massachusetts

Attleboro Comprehensive High School Oliver Ames High School Attleboro High School Pentucket Regional School Auburn High School Pope John XXIII High School Belmont High School Reading Memorial High School Bishop Fenwick High School Revere High School Bishop Stang High School Sharon High School Boston Community Leadership Academy St. Mark's School Boston Latin School Tewksbury Memorial High School Boston Latin Academy The Bromfield School Bridgewater-Rayham Regional High School Walnut Hill School Burlington High School Wellesley High School Cambridge School of Weston West Roxbury High School Coyle Cassidy High School Weymouth High School Danvers High School Durfee High School East Boston High School New Hampshire Fontbonne Academy Framingham High School Bishop Guertin High School Gloucester High School Calvary Christian School Groton Dunstable Regional High School Central High School Hingham High School Concord High School Holliston High School Franklin High School Hopkinton High School Franklin Pierce College Hudson Catholic High School Goffstown High School Hull High School John Stark Regional High School Lawrence Academy Londonderry High School Lawrence High School Manchester Central High School Lexington High School Nashua High School South Locke Middle School Oyster River High School Lowell High School Pinkerton Academy Lynnfield High School Portsmouth High School Maimonides School Wilton-Lyndeborough Co-Op Malden High School Wilton-Lyndeborough High School Marlborough Middle School Medford High School Medway High School Connecticut Methuen High School Middlesex School Branford High School Milton Academy Milton High School Rhode Island Natick High School Needham High School Cumberland High School Newton Country Day School North Andover High School Maine Northampton High School North Middlesex Regional High School Berwick Academy North Quincy High School Poland Regional High School North Reading High School Notre Dame Academy-Hingham Registration as of October 6, 2004

230

Environmental Research and Teaching

Third Annual Undergraduate Environmental Research Symposium Bridgewater State College Saturday, November 6, 2004 9:00 AM - 3:00 PM John Joseph Moakley Center

Symposium Program!

Abstracts of Poster Presentations!

Guest Speaker: Dr. Bill Freedman Department of Biology and School for Resource and Environmental Studies Dalhousie University, Halifax, Canada

Symposium Program Directions to the Moakley Center

Poster Titles & Abstracts 2004 BSC Campus Maps

Abstract Submission and Registration-closed Photo Gallery 2003

Contact Information Sponsors Announcement...... (PDF Poster here) The abstract submission deadline has passed.

SPONSORS Bridgewater State College Adrian Tinsley Program for Undergraduate Research The Canadian Studies Program Northeastern Section of the American Chemical Society

231

Bridgewater State College will host the Third Annual Undergraduate Environmental Research Symposium on Saturday, November 6, 2004. Undergraduate and graduate student research posters (including completed, in progress, and proposed research) in all environmental disciplines from colleges and universities in the Northeastern U.S. are welcome! In November 2003, over 100 Symposium attendees viewed the environmental research of 53 student preseters. We hope that this Symposium will provide an annual forum for discussion of environmental research and concerns particular to the New England region, and open doors to potential research collaborations among the participants.

To help defray costs, a registration fee of $10 is requested upon arrival. For additional information or to be added to our email distribution list, please contact the Symposium Coordinators: Ed Brush ([email protected]), Kevin Curry ([email protected]), Tammy DeRamos King ([email protected]), and Don Padgett ([email protected]).

Updated November 03, 2004.

232

Third Annual Undergraduate Environmental Research Symposium Bridgewater State College Moakley Center Saturday, November 6, 2004

Symposium Program

Poster Titles and Abstracts 2004 Return to Symposium Home Page

PROGRAM

8:30 - 11:00 Registration and poster set up in Moakley Atrium; coffee, juice and light breakfast

9:45 - 10:00 Welcoming Remarks in Moakley Auditorium: Dr. Ron Pitt, Associate Vice President for Academic Affairs, Bridgewater State College

10:00 - 10:45 Guest Speaker: Dr. Bill Freedman Department of Biology, Dalhousie University, Halifax, Nova Scotia "Environmental Impacts of Forest Harvest Practices in Canada"

11:00 - 2:00 Poster Session, Moakley Atrium (even number presenters 11:00-12:00, odd number presenters 1:00-2:00)

12:00 - 1:00 Lunch, Moakley Atrium. Poster discussions may continue informally through lunch

Poster Session Titles: Moakley Center Atrium (11:00 AM - 2:00 PM)

Board #1. The effects of small impoundments of aquatic ecosystems of the Little River. Joseph Morini, Kelsey Ketcheson, and Dr. Michael Vorwerk, Westfield State College, Environmental Science Program, Westfield, MA 01086.

Board #2. The Effects of Lynch Dam on Water Quality. Andrea Palpini, Nick Corsini, Roland Deblois, Adam Rzegocki, Caitlin Turner, and Dr. Michael Vorwerk, Department of Environmental Science and Regional Planning, Westfield State College, 577 Western Ave., P.O. Box 1630, Westfield, MA 01086.

Board #3. Small Dams and their Effects on Local Aquatic Ecosystems. Eric Rubenstahl, Joseph Runnals, Garrett La Scola, Derek Casale, Chris Visone, Douglas Grant, and Dr. Michael Vorwerk, Department of Environmental Science, Westfield State College, 577 Western Avenue, P.O. Box 1630, Westfield, MA 01086.

Board #4. The Effects of Littleville Dam on the Aquatic Ecosystem. William J. Borowiec, Jessica

233

Johnson, Bill Moncy, Dave Ennaco, Candace MacDonald, and Dr. Michael Vorwerk, Westfield State College, Environmental Science Program, Westfield, MA 01086.

Board #5. The Effects of Parking Lot Runoff on the Westfield River. Darren Guertin, Eric Rubenstahl, and Dr. Michael Vorwerk, Departments of Environmental Science and Geography & Regional Planning, Westfield State College, 577 Western Avenue, P.O. Box 1630, Westfield, MA 01086-1630.

Board #6. Analysis of Nutrient Levels in the Muddy River, Boston. Regina Dagher, Johnathan Bluhm, Emanuela Pandeli, and Dr. Faina Ryvkin, Chemistry Department, Emmanuel College, 400 The Fenway, Boston, MA 02115.

Board #7. Lake Sunapee Watershed Portfolio. Tamsen Bolte, Jenni Beaulieu, Joe Jennings, Paul Barrile, Matthew Cummings, Emily Goodrich, Gordon Krantz, Micah Mitchell, Stacey Philbrook, Greg VanSteinburgh, Sarah Young, Dr. John Callewaert, Dr. Laura Alexander, Dr. Aimee Ayers, and Dr. Leon-C. Melon, Institute for Community and Environment, Colby-Sawyer College, 541 Main St., New London, NH 03257.

Board #8. Effect of Nutrient Enrichment and Salinity on Salt Marsh Invertebrates in the Plum Island Estuary. Jenn Kerry and Dr. Dorothy Boorse, Biology Department, Gordon College, 255 Grapevine Road Wenham, MA 01984, and Dr. Robert Buchsbaum, Massachusetts Audubon Society, 346 Grapevine Ave., Wenham, MA 01984.

Board #9. Enzymatic Degradation and Analysis of Environmentally Benign Photo Polymers. Justin Whitfield and Dr. John C. Warner, Department of Chemistry and School of Health and the Environment, University of Massachusetts Lowell, 1 University Ave., Lowell, MA 01854.

Board #10. Green chemistry synthesis of 3-bromooxindole-3-acetic acid: An intermediate to a number of indole-derived therapeutic enzyme inhibitors. Jesse Miller and Dr. Ed Brush, Department of Chemical Sciences, Bridgewater State College, Bridgewater, MA 02325.

Board #11. An investigation of the application of ionic liquids as "green" reusable solvents for the synthesis of 3-bromooxindole acetic acid. Evan Broderick and Dr. Ed Brush, Department of Chemical Sciences, Bridgewater State College, Bridgewater, MA 02325.

Board #12. Above and Beyond the Call of Organic Chemistry. Raksmey Im, Hogan, P., Romasco, R., Church, J., Diloreto, M., Haskins, M., Mallon, Z., Nenadovic, M., Stocking, E., Tarasuk, V., Vallee, V., and Dr. Patricia Hogan, Department of Chemistry, Suffolk University, 41 Temple Street, Boston, MA 02114.

Board #13. Diet Analysis of Nesting Crested Caracaras in South Central Florida. Kyle Pias and Dr. Joan Morrison, Biology Department, Trinity College, Hartford, CT 06106.

Board #14. A Comparative Flower and Seed Study Between Common and Endangered Nuphar Species of New England. Paul A. Muller, Jr. and Dr. Don Padgett, Department of Biological Sciences, Bridgewater State College, Bridgewater, MA 02325.

Board #15. Armillaria gallica and Armillaria mellea Show Phenotypic Plasticity for Growth on Host Species Extracts. Elisha Allan, Heather Bickford, Amy Curdie, Rob Doiron, Dr. Maura Tyrrell, Dr. Robert Peabody, and Dr. Diane Peabody, Biology Department, Stonehill College, 320 Washington Street, Easton, MA 02357.

Board #16. A Comparison of Selected Microorganisms in River and Pond Sediments in Watersheds of Southeastern MA. Megan Lakhal and Dr. Patricia Mancini, Department of Biological Sciences, Bridgewater State College, Bridgewater, MA 02325.

Board #17. Population dynamics of a breeding population of Spotted Salamanders (Ambystoma

234

maculatum) on the Wheaton College Campus. Barthram Krishnamoorthy, Ashley Kriwinsky, Dr. Scott Shumway, and Dr. Kathleen Morgan, Department of Biology and Department of Psychobiology, Wheaton College, 26 East Main Street, Norton, MA 02766.

Board #18. Seasonal Variation in Water Quality and Benthic Macro-invertebrate Diversity in New England Vernal Pools. Nicole Anderson, Cara Marchese, Molly Troup, and Dr. Kathleen Morgan, Program in Psychobiology, Wheaton College Norton, MA 02766.

Board #19. Microsatellite Markers in Conservation Biology. Liz Jacques and Dr. Barbara Brennessel, Biology Department, Wheaton College, Norton, MA 02766.

Board #20. Asthma, Awareness, and Education. Michael C. McLaughlin and Dr. Catherine A. Roberts, Department of Mathematics, College of the Holy Cross, 1 College Street, Worcester, MA 01610.

235

From The Nucleus, February 2004

An Employment Guide for ACS Members: Mukund S. Chorghade, Elaine Diggs, Truman Light, Arlene Light, Bruce Millar, Dorothy Rodman, Jura Viesulas, ACS Department of Career Services, 1155 16th Street, N.W. Washington D.C. and the Northeastern Section of the ACS.

Note: This guide is meant to serve as a basic information resource in areas of concern to chemists. Information was compiled from published sources that we deemed reliable (see Bibliography and Appendix lists). Readers should con-sult the appropriate authorities for additional information or assistance beyond the scope of this guide. The American Chemical Society (ACS) does not guarantee employment to any reader of this document or accept responsibility for se-ting standards for any topic discussed within. ACS and the authors are not responsible for the accuracy of information obtained from other sources.

During five years in Japan as a postdoctoral fellow in both academia and industry, Salvador G. Alvarez says he “lost touch” with the U.S. job market. When he decided to return in 2000, he didn’t know where to start looking for a job, how to market himself, or even how much he could expect to earn. But, within three months of his return, Alvarez landed his “dream job” as a senior scientist at Versicor Inc., a biopharmaceutical company in Silicon Valley. Along with generous stock options and excellent benefits, he is earning a salary that exceeded his most optimistic estimates. As an added plus, his new job allows him to collaborate with Novartis Pharma AG, his employer in Japan, enabling him to continue working with similar classes of compounds.

Lucky? Alvarez doesn’t think so. He credits ACS’s Department of Career Services (DCS) with helping him find his new job by providing him with current salary data and tips on writing excellent cover and thank-you letters, and by shrinking his “wordy” résumé from four pages to two. First, he read through DCS’s popular publications, “Tips on Résumé Preparation” and “The Interview Handbook.” Then, he forwarded his résumé to DCS for a review. It came back with a sea of red ink. “I was using too many words to get to the point. It was as if I was writing a curriculum vitae for academia,” Alvarez recalls. “What I got back after it was over hauled by DCS staff members was very impressive.”

Since its beginnings, the member-oriented DCS has provided career development assistance to tens of thousands of chemists and chemical engineers and has become one of the most valued of all ACS member benefits. “Younger ACS members count on DCS for valuable assistance in molding their careers”, says Nancy R. Gray, director of ACS’s membership division, which includes DCS. “It is the time of their lives when they are looking for reputable information that is relevant to their skills, and they want to make sure that they maintain marketability,” Gray says. “They look to ACS to know what the chemical industry and academic endeavors are looking for in hiring and promoting.” One of DCS’s longest standing member benefits is the National Employment Clearing House. NECH is the largest single drawing card at each of the society’s two national meetings; operating as a vast interview site matching employers and job seekers DCS also conducts eight Regional Employment Clearing Houses (RECHs) each year. Begun in 1937 in a hotel parlor in Rochester, N.Y., NECH has grown phenomenally during the past six decades. The first NECH drew 128 job candidates and 77 employers. At the 2001 Chicago national meeting, NECH occupied in excess of 139,000 sq ft— The clearinghouse attracted 169 employers who had 1,392 open positions to fill—more posi-tions than the 1,112 job candidates on hand. At all future

236

national meetings, pre-registration for NECH will be conducted entirely online. This innovative service will make it more convenient for employers to set up interviews and to e-mail job seekers prior to the meeting, curtailing lengthy lines for on-site registration.

“The “electronic NECH” is one example of DCS’s intention to offer members a balance of expanded convenience while still providing its hallmark personal attention that is tailored to the needs of chemical professionals”, says Jean A. Parr, former director of DCS activities. “DCS differs from commercial job-hunting services by offering personal, chemist-to-chemist attention and by drawing on its knowledge and understanding of the chemical workplace”, she adds. “We couldn’t accomplish what we do without the nearly 200 career consultants and local section coordinators who spread the word,” Parr notes.

For each national meeting, DCS organizes the Career Resource Center, or CRC, which functions as one-stop shopping for job candidates attending NECH. Before they interview, they can polish their résumés in one-on-one sessions with seasoned academic and industry professionals or obtain a videotaped critique of their interviewing skills. They also can gain practical job-hunting skills and broader knowledge of the chemical workplace by attending one of 38 workshops or by visiting the CRC’s career development library.

Samina Azad, now a postdoctoral fellow at Pacific Northwest National Laboratory, credits CRC’s comprehensive programs with providing her with what she terms “the whole story” of how to find a job. Before the interviews at each of three NECHs Azad attended, she divided her time between résumé reviews, mock interviews, and career work-shops. During those sessions, she “learned all the secrets” about how to be professional, how to respond to questions, and how to answer what the interviewer really wants to know. “I will remember those tips from the mock interviews for the rest of my life,” she says. “Things like posture: The way I was sitting down wasn’t very professional. I would sometimes pause audibly before saying something. I would also say, ‘Yeah’—you have to say, ‘Yes.’ Also, I would sometimes take too long to answer questions.” Azad, who obtained her master’s in Bangladesh and holds a doctorate in physical chemistry, says she learned one important tip from a résumé-review session that led directly to a job offer. Her reviewer advised her to list her profes-sor’s name on her résumé. Later, when an employer attending NECH picked up her résumé, he happened to know her professor. “That was the magic thing. It really worked very well,” she says.

According to Azad, NECH is an effective job-hunting place because job seekers have a clear idea of what jobs are posted and which employers have expressed an interest in them, and they can schedule several interviews, all within the range of two or three days. “It made me very confident about the whole job-hunting experience,” she adds. Azad credits the personal assistance of DCS staff and volunteers with her successful job search. But she says DCS’s comprehensive catalog of publications— books, booklets, newsletters, and pamphlets—also played an important role. Two titles she singles out because they provide a helpful description of the job market are “Current Trends in Chemical Technology, Business, and Employment” and “Managing an Effective Job Search.”

Distributing and producing timely publications about chemists and the chemical workplace are among the most important year-round services that DCS provides. Among the most popular titles are “The Interview Handbook,” “Tips on Résumé Prepara- tion,” and “Targeting the Job Market.” Other titles that are frequently requested are “Employment Guide for Foreign-Born Chemists in the United States” and “Coping with Job Loss.”

Last year, DCS introduced a new member benefit, the

237

ACS Salary Comparator. The comparator allows members to electronically evaluate their salaries in relation to other members in their own employment situation. It also allows members to examine any employment situation within the scope of the ACS salary surveys, including new graduates’ starting salaries.

The Career Consultant Program is another DCS activity that provides year-round member assistance. Established in 1990, the program provides individual- ized career guidance delivered by a corps of more than 60 volunteer career consultants. They are ACS members, mostly experienced career chemists, who are available by telephone and e- mail to assist members at all career stages that are seeking advice and direction. The service is free and completely confidential. Since its inception, the program has served more than 3,000 members (excluding services provided at national meetings).

George J. O’Neill, a retired research chemist from Eastman Chemical, has been a career consultant for two-and-a- half years. He says his primary interest in joining the program was having the chance to continue mentoring younger chemists and helping them select their career path.

Preparing for the Job Search: Factors to Consider Employment Trends Before you venture out on a job search, you should have an understanding of general employment trends. Today there is less security in employment. Permanent employment with one firm throughout one’s career is rare. Frequent career moves are very common and are no longer considered a stigma as long as the career moves indicate upward progres-sion. Management layers have been eliminated, creating flatter organizations. It is a given that flexibility, adaptability, and good verbal and written communication skills are almost always required to complement technical skills. Every employer’s goal is to achieve staff downsizing while attaining required production or work output with a core staff. Teamwork has replaced a multi-layered system of management. Whether a particular job market involves customer-driven production or research, a business sense is important in addition to technical background.

An ability to work in a diverse workforce is important. The outlook on work, production, business, research, or any other area that affects employment is usually geared to a global market. The industry is moving toward the emergence of small firms of between 50 and 500 employees that tend to hire professionals with multifaceted skills and knowledge. Small companies are hiring BS chemists with marketing, sales, customer service, and research and development (R&D) experience. Medium-sized companies hire for replacement and some growth and require chemists at all degree levels.

Identifying Resources to Target and Research Employers in the United States It is beneficial for every chemist to consider membership in one or more professional societies to make use of the variety of services available to members seeking employment. Once you have identified companies that you wish to target, you can access other types of career assistance through the ACS or other professional societies in your field. ACS also maintains an electronic recruitment site where chemists can post resumes and employers can post jobs they are attempting to fill. To visit the site, go to http://chemistry.org and follow the appropriate navigation.

Professional societies offer employment services, including referral services or clearinghouses, which are held at several locations. ACS operates the NECH at its semi-annual national meetings. Pittcon, and AIChE employment clearinghouses are among other major events available for chemists and chemical engineers to make contact with employers and access employment opportunities.

Professional data banks and résumé referral services are also services that enable you to obtain exposure to employers. These services are available throughout the year and are based on matching a candidate to the needs of an employer. Being active in a professional society will also lead to

238

networking opportunities with other professionals in your field. Become active in the local section of your society. Join an ACS division, present a paper or poster at a meeting, or volunteer to serve on a committee or task force. Any of these activities will make you and your abilities visible.

Networking: Networking enables you to learn about different aspects of the chemical industry and the types of positions available in various companies. Networking will also help you to develop job search strategies, particularly if you wish to target specific companies, meet different people to obtain information and ideas, and obtain further introductions that can foster important job leads.

Keep your contacts informed if they have helped you get good information or job leads. This feedback can be verbal or a written thank-you note or e-mail mentioning the progress you have made as a result of your contact. Those who have extended themselves to help you always appreciate such follow-up.

An analysis of data from the ACS 2001 starting salary showed that 20% of B.S. chemists, 22% of M.S. chemists, and 22% of Ph.D. chemists found jobs through personal contact, while only 10% of B.S. chemists, 8% of M.S. chemists and 1% of B.S. chemists were hired after responding to newspaper ads. Networking contacts can be made through various sources, including fellow workers, former workers and/or supervisors, previous subordinates, competitors, clients, consultants, customers, sports groups, church groups, hobby groups, relatives and neighbors, teachers, stockbrokers, fellow commuters, lawyers, accountants, physicians and dentists, e-mail groups, and the World Wide Web.

ACS local sections offer opportunities to make contacts and network on a local level. Local section participation is also useful in developing skills through making presentations and volunteering on committees and projects. Involvement in a professional society at the local or national level can give you considerable exposure and networking contacts that may prove invaluable in your job search and your career development.

Communication skills, especially good listening skills, are very important in successful networking. Develop such skills, if necessary. Pay attention to facial expressions and tone of voice. Rephrase what someone has said to clarify information and avoid misunderstanding. Whenever possible, check information for accuracy, and ask questions. Show interest in other people and give back to your network as well as using the network to meet your own needs.

Classified Advertising Classified ads in newspapers and professional journals pro-vide information on job openings. The ACS weekly magazine, Chemical & Engineering News is a good source of advertising by employers. Other magazines for information on job openings include Nature, New Scientist, and The Chronicle of Higher Education.

Recruiting Agencies Employment agencies and search firms should not be discounted in a job search. Small companies that do not have established human resource departments use the services of recruiting agencies and search firms to seek candidates. However, check the credentials of such companies and use only reputable agencies with proven track records. Usually, the employer retains the agency for a fee. Be particularly cautious about recruiting agencies that require a fee from the applicant.

Electronic media can help you locate positions through the Internet at any hour of the day or night. Not only can you search for positions, you can also provide your résumé electronically. However, be cautious in providing any information about yourself online. A résumé posted online becomes public property, and it could end up in places you do not expect or want. Your current employer may also stumble upon it while searching for other candidates like yourself

How Do I Market Myself? There are four categories of skills: people, things (e.g., equipment or materials), information/data, and ideas/concepts. To market yourself, you need to clearly, qualitatively and quantitatively identify your

239

accomplishments, skills and strengths and prioritize them in relation to what you want to use in a new job. Often, accomplishments are greater in the skill areas that you enjoy. You will need to make an assessment of what you are looking for in potential employment, examine the kinds of opportunities available in those areas and be aware of what employers find most valuable in the current hiring market.

Technical skills must be combined with many other skills, non-technical or innate, that together bring success in a career: Interpersonal skills are an important component of an applicant’s total skills set and are highly valued by employers. Sample Skills: A) Technical: 1) Acquire technical knowledge to do the job. 2) Develop technical skills through continuing education. 3) Develop research abilities. 4) Learn through-out a career; be dedicated to continuous learning. 5) Learn about fields outside chemistry. B) Communication: 1) Communicate verbally and in writing. 2) Sell ideas and be persuasive in presenting a point of view to others. 3) Develop good listening, presentation, and interpersonal skills. C) Problem Solving: 1) Use complex data and intuition to reason and draw conclusions. 2) Be customer-oriented in problem solving. 3) Be persistent in seeking an answer. D) Initiative/Judgment: 1) Set and meet (or exceed) specific and realistic goals. 2) Use good judgment about taking risks. 3) Evaluate critically and constructively. 4) Be innovative, self-motivated, assertive, and self-starting. E) Creativity/Innovation: 1) Formulate new ideas and solutions. 2) Create new ways of doing things better. F) Leadership: 1) Identify key issues and use available resources to formulate strategies to achieve goals. 2) Get commitment from others and work in a team toward common goals. G) Team work: 1) Work well with people at all levels of knowledge and competence. 2) Work with people ofother cultures.

Preparing Your Résumé: The most important marketing tool in your search for an industrial position is your résumé that is well presented, highlights your qualifications and abilities and provides a clearly stated summary of your credentials and professional expertise. A résumé does not get you the job but is the key to obtaining an interview.

Your résumé must express a sense of purpose, stated as an objective, concerning the type of position you seek. An objective should not be too broad or vague; it must be supported by the necessary skills and experience on your résumé that fit the position. Some employers prefer to see an objective while others do not attach importance to it. If you include an objective, tailor it to match the specific position for which you are applying.

It is very important to emphasize your achievements showing how your work had a significant impact on an employer’s business and not merely to list job duties and responsibilities. If possible, quantify achievements, but do so accurately. For example, if your work resulted in reducing production costs by 20%, say so. Information in your résumé should never be exaggerated or falsified. Use clear, simple language easily understood by an employer. For past positions held, state job titles accurately. The facts stated must be accurate, impressive and true. Your résumé give a sense of the person you are and how you work with others.

Tips on Résumé Writing: Employers usually spend no more than 30 seconds reading a résumé; therefore, your résumé must be carefully prepared to attract attention and to give you a competitive advantage over other job applicants.

Paper, Typeface, and Design: Remember that the paper you use should be able to withstand a great deal of handling. Office supply stores carry special quality paper recommended for résumés. Also, résumés will be copied several times and distributed to different individuals in an organization, so be sure that the print on your résumé gives clear copies. The color of the paper should not obscure the print when making photocopies. Shades of gray, blue, green, or any other colors that give a shadow when copied should be avoided. White, cream, or light buff shades are recommended.

Select a font that does not run together and is easy to

240

read. Usually Prestige Elite, Courier, Arial, and Times New Roman fonts print clearly if your résumé is prepared on a personal computer. Use only one type of font on your résumé. Boldface, italics, underlining, or bullets can be used sparingly for emphasis. A résumé should not be crowded, cluttered, or difficult to read. Provide plenty of clear white space with a one-inch margin all around. Employers need space to make notes on the résumé during interviews. Your résumé should not exceed two pages. If you have a long list of publications, presentations, and patents, prepare a separate list.

Writing Style: Do not use the first person “I” in writing your résumé. Describe your accomplishments using active verbs, such as “developed,” “evaluated,” and “analyzed.” Grammar and spelling must be correct. After your résumé is prepared, make sure that at least two people with good language and proofreading skills review it and determine whether it reflects positive information about you and the type of employment you seek.

Do not include personal information regarding age, height, weight, health, marital status, number of children, or race on your résumé. It is inappropriate to include a photo-graph. Confine information about yourself to that which is relevant to the job itself – talents, education or experience that will enhance your performance in the job.

Sometimes a section on “Highlights” or Summary is used instead of an objective. These should briefly describe your employment history and highlight the key areas that you want to “sell” to a prospective employer.

Résumé Formats: The Chronological Résumé: The chronological résumé should be used when you are seeking your first job, have a career sequence without gaps in employment, and you need to show progression in the same field in your area of expertise. This type of résumé is acceptable in traditional organizations and organizations requiring specialization and progression in one particular area of work.

Components of a Chronological Résumé: Heading: name and address; at least two telephone numbers (day and evening); e-mail contact information Objective: should be tailored to a specific position, if known; and linked to a function, specialty, organizational level, and type of organization Educational background: •a list of degrees received, in reverse chronological order with the highest degree first • the name of the school and date of graduation (if you are a new graduate) • the PhD dissertation title and the advisor’s name (if you are a new graduate); and • the type of equivalency you received if your education was overseas Research / Work experience: • most recent position first • title, duties, and responsibilities (use active verbs) • quantified details of successes achieved in the position • recent jobs only, do not include jobs held more than 10 years ago. • military service information should state whether service was in the United States. Special skills: • languages, computer skills, instrumentation • leadership positions held • any other skills outside your technical area that were acquired through paid or volunteer work

Professional affiliations and awards: • membership in professional societies/associations and special awards received. •A list of publications, presentations, and patents should be provided on a separate sheet References:

241

• List references only if you are a new graduate; not if experienced. • Provide references after getting an opportunity to interview. • Be aware of the referee’s relationship to the company offering a position. • Inform referees about the type of position and employer. • Discuss with the referee details about yourself such as your strengths and achievements. • Provide the referee with a copy of your updated résumé. • Mix referees to cover academic and business contacts.

Functional or Skills-Based Résumé should be used when you are changing career paths, attempting a transition into another type of employment with existing skills, de-emphasizing your age or gaps in employment history, emphasizing the value of your extensive experience, The advantages of using a functional résumé are the opportunity to present a variety of skills acquired in more than one field or outside regular employment and the de-emphasizing of a career with breaks or extensive job changes.

Components of a Functional Résumé: Several components are the same as those of a chronological résumé heading; objective; summary; education; military service; affiliations and awards; publications, presentations, and patents; and references. Additional components are as follows:

Skills and accomplishments • Identify and prioritize three to five of your most important skills applicable to the type of position • List and quantify other skills and accomplishments. •Work experience • List positions held, but do not list details of duties performed. • List your most recent position first. • Indicate experience in number of years if there are breaks in employment dates. • Limit mentions of experience to those of the past 10 years.

Applying for a Government Position: The OF-612 Federal job information can be accessed using a telephone, personal computer, or touch-screen computer kiosks located in cities throughout the United States. To obtain information through the Office of Personnel Management (OPM), call USA Jobs by phone at 478-757- 3000 (TDD service 478- 744-2299). This service provides information on federal positions available worldwide, including salary, employee benefits, and recruitment as well as how to receive forms and other information packages. The service is available 24 hours, 7 days a week.

You may complete the government employment form, the OF-612, use a federal resume or apply online at http://www.usajobs.opm.gov. A useful feature at this site is a link to a resume builder that allows a potential government employee to create and store an electronic resume for use in applying online for government positions in multiple agencies and departments.

In completing forms or online text boxes, pay close attention to the job announcement. You need to address the knowledge, skills, and abilities (KSA’s) required for the position. Add other information, even if it is optional. Each application is assigned points based on the KSA’s and optional information an applicant presents, so it is to your advantage to submit a thoroughly completed application. Since the U.S. government is a very large and complex organization, it has established formal application procedures to facilitate processing the many applications it receives and to ensure a fair, politically neutral hiring process. The prescribed procedures must be followed very carefully. Applicants that do not meet prescribed application

242

deadlines will be eliminated from consideration. Government positions that require a security clearance hire only U.S. citizens. In rare instances, a permanent resident status will be accepted. Information and a sample copy of the OF-612 form are available at http://www.cyber-comm. net/~digibook/.

You must provide the following information when applying for a federal position: 1) Position information, including job announcement number, title, and grade 2) personal information, including full name, mailing address, zip code, and two telephone numbers (day and evening) 3) Social Security number 4) country of citizenship 5) veterans’ preference, reinstatement of eligibility, and highest federal civilian grade held (if you are a veteran) 6) education, including high school name and location, college or university name and location, and degrees earned, with dates 7) work experience, including job titles, duties performed, accomplishments, employer’s name and address, supervisor’s name and telephone number, start and end dates of employment, hours worked per week, and salary (with a separate entry for each job) and 8) other qualifications, including on-the-job training, other job- related skills, certificates received, licensing held, and honors and awards for special accomplishments.

Curriculum Vitae for an Academic Position The tool used for seeking an academic position is the CV, which is longer than a résumé and should contain more information. In the CV, include a detailed list of all your publications and presentations and other significant accomplishments. Frequently, applications for academic positions will require letters of recommendation as part of the application packet.

Components of a CV: Heading: Use the title “Curriculum Vitae”; provide name, address, two telephone numbers and e-mail contact Education: Ph. D. is usually a requirement for an academic position. State your doctoral degree, the date it was received, your thesis title, advisor’s name, and the name of the university. Also provide details of any undergraduate degrees and graduate degrees you acquired, in reverse chronological order. Research interests: State these very briefly in a page or two. Professional activities and honors: List these in order of importance or in alphabetical order. Highlight any special honors or awards received. Publications-List all: • Publications/ Patents. • Participation in professional societies • Oral presentations Recommendations: List names and contact information of three or four individuals willing to write recommendation letters.

Cover Letter: A cover letter must be included with every résumé. It serves as an introduction to your résumé and invites the recipient to read the resume. Research the company and obtain names of the unit managers or the hiring manager with correct spellings and accurate titles. The cover letter should not exceed one page and should include information not already mentioned in your résumé.

The first paragraph of a cover letter should explain the purpose of your letter and the attached résumé. Be sure to mention whether you are responding to an ad or doing an exploratory mailing to seek an opening in the company. If you are responding to an ad, pay particular attention to the reference number of the position, if there is one. Also, your cover letter should indicate where and when you saw the ad. If you have been referred to an individual by a third party, state the name of the person who provided you with that contact.

In the second paragraph, indicate how your skills will

243

fit the department and project. Also, indicate how you will fit into the culture and purpose of the organization. Using what you have learned about the company and its long- and short-term goals, indicate what contribution you can make to its business or products.

In the final paragraph, express your desire to seek a position in the organization and indicate that you will be delighted to meet with the executives/ scientists/ managers at the company.

Submitting a Resume via E-mail or Applying Online: Many employers today are requesting that job appli-cants submit their resumes electronically. Some employers, in fact, no longer accept paper resumes. E-mailing your resume to the employer’s e-mail address is fast, easy, and eliminates postage and stationery costs. There are several factors to keep in mind, however, when using this mode of job application. First, beware of submitting your resume as an attachment to e-mail. Because of concerns related to the spread of computer viruses, an employer may be reluctant to open an attachment from an unknown sender. Instead, you should “cut and paste” your resume into the body of the e-mail or submit it as an attachment in plain text, also known as ASCII. To prepare a plain text resume, write a well-written resume in either Word or WordPerfect. Next, go to “File” in your word processing program and choose “Save as.” Save your resume as plain text (.txt file).

A second method of applying electronically for posi-tions in chemistry is to apply online. Many companies and governmental agencies not only encourage job seekers to apply over the Internet but actually prefer that potential employees do so. Go to the employer’s Web site and “cut and paste” your resume into the online text box that is a part of the job application form located somewhere on the Web site. This method simplifies the recruitment, screening, and applicant selection process for the hiring organization.

Preparing for the Interview After preparing a résumé and responding to suitable advertisements, you may be invited for an interview. A site interview will usually be a follow-up to an initial screening interview. The site interview is an in-depth interview in which your technical specialty and related skills will be presented. Because your competition is just as qualified as you are, you need to stand out by being the best interviewee. . It is important to demonstrate enthusiasm for your work, sincerity in your purpose, courtesy in your dealings with others, and tact in dealing with stressful or difficult situations.

The art of interviewing can be perfected with preparation and with actual practice. The main purpose of the interview is to generate an offer of employment. It is a crucial element in the employment process and an opportunity to make an excellent first impression. Remember the adage “You do not get a second chance of making an excellent first impression”. It is not appropriate to address salary and benefits at the first interview unless the interviewer takes the initiative to introduce this topic.

To prepare for an interview, make sure you know: 1) Yourself, your skills and abilities 2) Something about the company 3) Logistics of the interview, and 4) What to expect.

Be prepared to ask questions about the position.

Review any accomplishments that could be an asset to the potential employer and demonstrate skills you possess. Use examples to explain how you handled difficult situations, solved problems, and persuaded clients. Always remember to provide quantified results of your accomplishments whenever possible. By knowing something about the company, you will impress a potential employer. A company can be researched through standard directories and the local chamber of commerce or even by requesting the company’s annual report in the mail before your interview. Most companies have Web sites with information about themselves. Any local public library will have information on companies as well. When you research the company, remember to formulate and be prepared to ask relevant questions about the department, position, and the goals of the company. Also, discuss current market trends such as globalization and where the company hopes to head in the current economy.

244

Basic Logistics of Interviewing: Before the Interview 1.) Practice interviewing with a friend or spouse if possible; videotape and critique your practice interview 2). Attend ACS mock interview sessions at national meetings to take advantage of a videotaped interview 3). Take extra copies of your résumé, list of publications and patents, and any relevant information to demonstrate your achievements. 4) Prepare relevant job-related questions that you can ask the interviewer.

Sample Questions That You Should Be Prepared to Ask: • What opportunities are there for someone with my skills and background to grow and develop in the company? • Does the company offer any programs to support developmental goals and continuing education of employees? • Does the company support participation in professional association activities to encourage career growth? • Does the company offer advancement in a technical track and a management track? • How many executive positions are there in the company, and what is the turnover rate? What is the policy regarding promotions from within the organization? • What are the possible career paths from the position that I am interested in? •To whom does the position report? How are work results monitored? How frequently are work results checked? • How do new ideas get started in the company— through individual efforts, by committees, or by teams? • Are new organizational design methods being implemented to allow greater decision making at lower levels? • What type of management oversight exists in each unit? • Who gets rewarded in the organization? Teams? Individuals? •What factors are important for a successful manager (or technical person) in your organization? •How much travel is required for overnight and out-of-town assignments? •Does the organization have flextime? Job sharing? Work-at-home? Part-time employment? •What kinds of opportunities exist to support the development of research/new products that could be of value to the company? • What are the greatest challenges in the position? • How much autonomy is allowed in the position for the creation of new and interesting programs or products? • Are job rotations available to enhance professional growth or understanding of a particular issue? • Does the company have a policy to retrain staff in preference to reduction-in-force in tight economic times?

The Technical Presentation (Industry) In the technical presentation, your skills of presentation, as well as the technical content of your work, will be evaluated. The impression you make at a technical presentation is vital to your success at securing a job. If possible, obtain some advance information about the audience. It will be a further advantage if you have some information about the technical backgrounds of the decision-making individuals so that you can be well prepared for questions that might be asked. It is equally important to research the company. Knowledge about the direction of the company and its products will also put you in a position of strength in connecting your knowledge and abilities to the needs of the potential employer.

Your presentation need not be extensive and lengthy, and it should not include any confidential information that will jeopardize your current position or employer. You can make those conditions clear at the beginning of your presentation so that your audience is aware of your guidelines.

Your presentation should cover no more than three to five topics lasting about 30-45 minutes, with time for a few questions from the audience. Remember to highlight your accomplishments in the presentation. The material you use for the presentation should be well prepared. Overheads should be uncluttered or a PowerPoint presentation carefully constructed and rehearsed. Pare down your information so that the audience can absorb the major points and important items.

245

Anticipate questions based on your work, and be pre-pared to substantiate answers to questions that may be asked. Listen attentively to questions asked by audience members. Your answers should be to the point, but make sure you fully respond to questions. Take questions from the audience in the order in which they are raised, and direct your response to the person asking the question. Practice will improve your presentation. Record your delivery if you can, and listen to yourself. Ask friends or colleagues to act as the audience while you rehearse, and solicit their feedback on your performance. Practicing will also give you an idea of how long your talk will take. Following are some tips for your presentation: • Practice your delivery. Be organized, to the point, and clear. • Briefly describe your research. Indicate the objectives, goals, results and conclusions of your research • Deliver your presentation with enthusiasm, confidence, and professionalism

During the Interview 1) Pay attention to your body language. Handshakes are usually initiated by the interviewer and should be firm. 2) Speak with confidence.3) Speak clearly and slowly 4) Maintain eye contact with the interviewer. 5) Be discreet with note taking.

After the Interview: Jot down important facts for future reference. And follow up by sending a thank-you note to the interviewer.

Selecting References for Employment Be prepared with about four to six names of people connected with your past employment. References need not be restricted to former supervisors. They could be obtained from peers, former bosses, consultants, or any other person in a position to observe your performance associated with your workplace. Keep your references updated with a copy of your current résumé, and refresh them in regard to your position and responsibilities. Discuss with your referees how they perceived your performance on the job, particularly in difficult situations. Pay attention to their comments to make sure they convey an accurate picture of your strengths and weaknesses. In addition to technical skills, employers pay particular attention to interpersonal skills, work ethics, communication, ability to adjust to change, and depend-ability. Employers will contact your references only if there is a genuine interest in hiring you. The final hiring decision could depend on favorable references, so do not neglect this aspect of the employment process.

Academic Positions Academic positions may include the following: tenured and non-tenured positions; adjunct, affiliate, or visiting appointments; research professional appointments with academic responsibilities; research professionals without academic responsibilities; postdoctoral research associates; postdoctoral scholars; and research associates.

The terms of employment for these different kinds of positions vary. You should become familiar with the procedure followed by each academic institution. Usually, academic faculty appointments are tenured or non-tenured appointments with responsibility for academic instruction and curriculum development. In academic positions, a letter of appointment is issued to a person when the position is temporary and a term is specified in the letter. A “letter of hire” in most academic institutions refers to a letter confirming tenure-track employment and indicating terms, condi-tions, and expectations of an appointment as an initial document, pending a formal contract from the governing body of the university.

Non-tenured positions are usually subject to the availability of funds in an institution. A non-tenured position can be terminated if funds are exhausted before the date of termination on a letter of appointment. A non-tenured position has no protection or claim to reappointment. Continuity is at the sole discretion of the academic institution. Non-tenured service is usually not counted in tenure appointments.

Research Seminar (Academe) Your research seminar takes approximately 45 minutes and should cover current research projects. Background material, techniques used, conclusions drawn, recommendations for future work, and types of support (including financial support) should be acknowledged. The problem under study should be concisely stated. Never lose sight of the fact that

246

your audience will include people who are very knowledgeable in your field. At an academic interview, you will be required to present your proposed research based on a written proposal. The time frame needed to complete the work and your sources for support should be included. Your work should be original, pertinent to the institution, and fundable by a supporting organization already identified. Again, practice and timing are important.

Planning for Career Success Your promotions and career success will depend largely on you. An employer will not always recognize hard work as deserving a reward in the form of a promotion, even if you are recognized as a valued and hard-working employee. Circumstances beyond the control of your employer such as mergers, restructuring, and other corporate upheavals may hinder your career progress. The “insurance” in such situations depends on your ability to keep yourself marketable. Never become so comfortable in your position that you sit back and await promotions and new job offers to come to you. Be assertive and learn to manage your own career. In performing your job, you need to go beyond the technical qualifications for the position. Be reliable and dependable, and show integrity. Long-term professional relationships must be built during the course of your career. Good relationships with associates are an outcome of good interpersonal skills. Although it is important to take time to help others, draw the line at taking over responsibilities for which others are accountable. Do, however, share experiences and communicate well.

Develop public speaking and writing skills, and look for opportunities outside your work and daily routine to enhance your professional skills. Get involved in selected professional and service organizations. Take time to become known and visible. Volunteer for special projects. If you understand the factors that will work to your advantage in the long run, your efforts will be rewarded.

Keep your technical skills current by staying abreast of developments in your field, and be familiar with emerging technology and innovations. Consider adding to your skill base by learning new areas, venturing into associated areas, and exploring other scientific disciplines. Science is not defined by clear boundaries, and your ability to interface in related areas will be of immense value over the course of your career.

Look for opportunities to cross-train in your workplace. There is no substitute for hands-on training and experience. However short term an opportunity may appear to be, something can be learned and a skill can be acquired that will stand you in good stead later. Volunteer projects can offer you the opportunity for exposure, learning, and broadening your experience.

Be flexible in your approach to all areas of your job. It is important to be able to work with what is available and to take a flexible approach to changes, unexpected situations, and challenges. Cultivate an ability to work in diverse teams with a mix of people of different ability and skill levels. Above all, maintain your professional network and contribute to the network as much as you receive. Taking con-trol of your career will undoubtedly reward you in the long run.

247

Bibliography: Bruce Millar, “Navigation Aids for a Changing Workplace,” Chemical and Eng. News, April 8, 2002, 14, pp77-80 American Chemical Society, Targeting the Job Market; American Chemical Society: Washington, DC, 2000. American Chemical Society, The Interview Handbook; American Chemical Society: Washington, DC, 1998. American Chemical Society, Tips on Résumé Preparation; American Chemical Society: Washington, DC, 1998. Axtell, Roger E., Do’s and Taboos of Hosting International Visitors; Wiley: New York, 1990. Beatty, Richard H., The Complete Job Search Book; Wiley: New York, 1988. Besson, Taunee, “Why a Scannable Version of Your Résumé Is a Must,” National Business Employment Weekly, Jan. 21-27, 1996. Bliss, Edwin C., Getting Things Done: The ABCs of Time Management; Macmillan: New York, 1991. Drake, John D., The Perfect Interview; AMACOM: New York, 1991. Graduating Engineer & Computer Careers; Career Recruitment Media, Inc., Evanston, IL, winter, 2002 Groban, Robert S., Jr. “The Immigration Act of 1990: An Employer’s Primer of Its New Provisions,” Employee Relations L. J 1991-92, 17(3), 357-82. Harris, Philip R.; Moran, Robert T. Managing Cultural Dif-ferences; Gulf: Houston, TX, 1991. Home Vision, “The Art of Dining,” “The Business Lunch,” “The Formal Dinner” (videos); Opera World: Concord, MA Mazzei, George. , The New Office Etiquette; Poseidon: New York, 1983. Medley, H. Anthony., Sweaty Palms: The Neglected Art of Being Interviewed; Ten Speed Press: Berkeley, CA, 1993. Millar, Bruce,“Immigration: Under the Microscope,” Chemical & Engineering News, September 23, 2002; Vol. 80, no. 38, pp. 81-87 Post, Emily, Emily Post on Etiquette; Harper & Row: New York, 1987. Rivera, Miguela, The Minority Career Book; Bob Adams: Holbrook, MA, 1991. Schermerhorn, John R.; Hunt, James G.; Osborn, Richard N., Managing Organizational Behavior; Wiley: New York, 1994. Schulman, Joel I. “Making Your Résumé Computer Compatible,” Today’s Chemist at Work 1995, 4(8), 43-46. Siegel, Martha S.; Canter, Laurence A, United States Immigration Made Easy; Sheridan Chandler: Tucson, AZ, 1990. Trompenaars, Fons, Riding the Waves of Culture: Under-standing Cultural Diversity in Business; Nicholas Brealey: London, U.K., 1993. Troutman, Kathryn K.; Sach, Laura; Ottenseyer, Mike; 10 Steps to a Federal Job, The Resume Place, Baltimore, 2002. Troutman, Kathryn K., Electronic Federal Resume Guide-book; The Resume Place, Baltimore, 2001 Troutman, Kathryn K.; Dobson, Michael Singer, The Federal Resume Guidebook, 2 nd ed.; JIST Works, Indianapolis, 1999. Yate, Martin, Knock ‘em Dead 1999: The Ultimate Job Seeker’s Handbook; Bob Adams: Holbrook, MA, 1999.

ACS Career services are available to all ACS members, including full members and national and student affiliates. For more information or career assistance, contact ACS Career Services by calling 800-227-5558 or by sending e- mail to [email protected].

Note: Additional resources may be found in the February 2004 issue of The Nucleus – posted on the NESACS web site at http://www.nesacs.org

248

ANNUAL REPORT Northeastern Section, ACS

APPENDIX 6 YOUNGER CHEMISTS COMMITTEE REPORT

http://www.nesacs.org

249

APPENDIX 6 – Younger Chemists Committee Report

Northeastern Section LSYCC Annual Report 2004 Submitted by Lauren K. Wolf, Chair NSYCC 2003-2005 (follows formas prescribed by ACS)

I. Overall Evaluation

In 2003, the Northeastern Section Younger Chemists Committee (NSYCC) became more organized, launching a new website, and establishing officer positions and responsibilities. In 2004, the committee built upon this improved organization and began a phase of expansion.

The goals for 2004 were to increase committee membership, increase attendance at established events, and to organize new events. As of the writing of this report, the YCC has 155 members on its mailing list – a significant improvement over 2003. Our successful website has also seen approximately 3400 hits in the past year. Attendance at our established annual events, the Career Symposium and the Northeast Student Chemistry Research Conference (NSCRC), also doubled in 2004. We attribute this increase to better advertising of events, both through the website and through mailing lists, posters, and fliers.

During the week of our annual German Exchange Program, we also organized a new event, the successful Northeast Student Chemistry Career Fair (NSCCF), which drew ~120 younger chemists. Several of the attendees came away from the event with job interviews and offers (see below). We also involved a large number of Boston-area younger chemists in the German Exchange Program this year by filling the schedule with events such as a Red Sox game and Symphony performance. For the first time, the YCC was able to attract corporate sponsors and thus, arrange these quality events and tours. Happily, our goals for 2004 were met.

II. Officers and Members The Annual Report is submitted by the NSYCC Chair each year.

LSYCC Officers

Lauren K. Wolf – Chair Department of Chemistry Boston University 590 Commonwealth Ave., Boston, MA 02215 [email protected] (617)353-3241

Ivan Korendovych – Assistant-Chair Department of Chemistry Tufts University 62 Talbot Ave., Medford, MA 02155 [email protected] (617)627-5745

Sonia Taktak – Secretary/Treasurer Department of Chemistry Tufts University

250

62 Talbot Ave., Medford, MA 02155 [email protected] (617)627-5745

Aida Herrera – Career Chair Department of Biological Engineering Massachusetts Institute of Technology 77 Massachusetts Ave., Cambridge, MA 02139 [email protected] (617)253-5772

Slava Azev - Webmaster Department of Chemistry Tufts University 62 Talbot Ave., Medford, MA 02155 [email protected] (617)627-2042

YCC Mentors

Dr. Amy Tapper – Past YCC Chair, NESACS Chair-Elect 2004 Peptimmune [email protected]

Dr. Michael Strem – Chair of German Exchange Steering Committee Strem Chemicals, Inc. [email protected]

Dr. Ruth Tanner – Chair of NESACS Education Committee University of Massachusetts - Lowell [email protected]

Dr. Morton Hoffmann – Past NESACS Chair Boston University [email protected]

Dr. Anthony Fernandez – Member of German Exchange Steering Committee Merrimack College [email protected]

Dr. Cassandra Celatka – Member of German Exchange Steering Committee [email protected]

YCC Members

Northeast Student Chemistry Research Conference (NSCRC) 2004 Subcommittee Chairs: Lauren Wolf Boston University [email protected] Webmaster: Viatcheslav Azev Tufts University [email protected]

251

Program and Printing: Sujata Bardhan Boston University Trina Foster Boston University [email protected] Gifts: Aida Herrera MIT [email protected] Sonia Taktak Tufts University [email protected] Journals: Ivan Korendovych Tufts University [email protected] Advertisement: Truc Diep Boston University [email protected] Dawn Troast Boston University [email protected] Lauren Wolf Boston University [email protected] Registration: Samantha Desmarais Dartmouth College [email protected] Erin Dieckman Merrimack College Christina Fields Harvard University [email protected] SuzAnn Hertzler Boston University [email protected] Claudia Moura Merrimack College

III. Activities

Schedules, photographs, and detailed information about each of this year’s activities are available on the NSYCC website, www.nsycc.org.

Career Symposium 2004: Careers in Communicating Science (February 12)

The annual YCC Career Symposium was held on February 12, 2004 from 3:30-5:30pm prior to the NESACS monthly meeting at Boston College in Chestnut Hill, MA. C&EN 2003 Associate Editor Susan Morrissey reported that to really stand out to employers, job candidates need to have the appropriate combination of scientific and communications skills. (C&EN Nov. 24, 2003) This year, the YCC tried to illustrate to the attendees of this symposium that communication is one of the most important aspects of science with our theme of careers in communicating science.

The speakers included Professor B.D. Colen of MIT, a Pulitzer Prize-winning medical writer, Professor A.L. Utz of Tufts University, a distinguished scientist speaking about chemical education, and Mr. A. Dichner of BioPro Inc., a recruiter giving advice on effective communication during interviews.

Each of these speakers shared their personal career experiences and answered questions from the attending students. They fielded questions on everything from how to get involved in science reporting, to how to balance teaching and research in Academia, to how to negotiate salary with potential employers.

The symposium was a great success because ~45 younger chemists attended, increasing the attendance from last year’s event by approximately 20. The NSYCC was also able to add 30 new email addresses to our membership list as a result of the event. In the future, however, the YCC would like to increase the number of attendees who stay for the monthly meeting and dinner (this year, it was only about half). The featured speaker for the evening meeting was Dr. William Carroll, Jr., ACS President- Elect 2004.

Fourth Annual NESACS-YCC/GDCh-JCF Exchange Program (April 18-25)

252

This year’s week-long exchange between the Gesellschaft Deutscher Chemiker- Jungchemikerforum (German Chemical Society - Younger Chemists Committee) and the Northeastern Section Younger Chemists Committee, held during the week of April 18, was a great success. Thirteen German Ph.D. students and three delegates traveled to Boston to participate in the week’s events, arranged by the YCC and Steering Committee. Day-by-day events were as follows:

Sunday, April 18: Check into hotel, The College Club on Commonwealth Ave., visit the top of the Prudential Center, and have dinner with YCC officers, past program participants and some of the steering committee at Durgin Park in Faneuil Hall.

Monday, April 19: Patriot’s Day: Attend the Red Sox-Yankees game with a group of younger chemists at Fenway Park. The Red Sox won! Break up into groups to watch the Boston Marathon and cheer on our own Chair-Elect, Amy Tapper, as she headed towards the finish line.

Tuesday, April 20: Morning tour of the chemistry department at MIT. Lunch at the Border Café in Harvard Square. Afternoon tour of the Harvard campus and chemistry department.

Wednesday, April 21: Morning bus trip to Pfizer in Groton, Connecticut. Lunch in Pfizer cafeteria, presentation on drug discovery, tour of laboratories in the new Drug Discovery building. Bus side trip to Newport, Rhode Island. Brief walk along the ocean-side cliffs near the famous mansions. Dinner at Christie’s on the bay in Newport. Evening bus trip back to Boston.

Thursday, April 22: Morning trip to the Museum of Fine Arts. Presentation on authentication and preservation of art and artifacts. Tour of authentication and preservation laboratories with connection to chemistry and analytical tools. Lunch in the MFA cafeteria. Guided tour of certain pieces of American art in the museum’s collection. Students have afternoon free time in the museum. Evening meeting by the German and NESACS steering committees at the Armani Café to discuss the future of the Exchange Program. Many interesting points were brought up and we have been invited to again send students to Germany in 2005. The Euregionale will be taking place in Berlin next year. Evening Boston Symphony performance (attended by many NESACS members).

Friday, April 23: Career Fair organized by the YCC held at the Brookline Holiday Inn. (See Career Fair for details.) Evening dinner sponsored by Genzyme at Jacob Wirth’s. Four Genzyme representatives, YCC officers and Dr. Charles Casey (ACS President, 2004) and his wife attended and mingled with the German students.

Saturday, April 24: 6th Annual Northeast Student Chemistry Research Conference organized by the YCC held at the Photonics Center at Boston University. (See NSCRC for details.) Evening farewell banquet held in Boston University’s Management Building. In attendance were members of the German exchange steering committee, the NSCRC organizational committee, NESACS officers, Dr. Charles Casey and wife, Dr. Stephen Lippard and wife, as well as the German students and delegates.

Sunday, April 25: Depart for Germany.

The German students who participated were selected by the GDCh based on their accomplishments in research, their interests, and participation in the JCF. Our steering committee, consisting of Dr. Amy Tapper, Dr. Michael Strem, Dr. Ruth Tanner, Dr. Anthony Fernandez, Dr. Cassandra Celatka, Dr. Morton Hoffmann and the YCC officers, organized the week’s events and accommodations. Two of the German students gave oral presentations at the NSCRC. The remaining students presented posters. Christian Ducho of Hamburg took the top prize for his oral presentation. Two poster prizes were also awarded to Frank Sischerl (University of Konstanz) and Melanie Schnell

253

(University of Hannover). A report was written by our steering committee and published in The Nucleus (the NESACS monthly newsletter). The article, as well as photographs and programs, can be found on our website under “German Exchange 2004.”

Northeast Student Chemistry Career Fair, NSCCF (April 23)

This event was the first of its kind ever to be organized by the YCC. Held at the Brookline Holiday Inn, it began with a set of morning workshops on resume writing and interviewing. These workshops were hosted by Daniel Eustace of ACS Career Services. Mr. Eustace engaged the ~80 workshop-attending students in discussion about searching for a job and even held a mock interview to illustrate good and bad interviewing behavior. ACS Career Services booklets and materials were also provided to all attendees. During the afternoon job fair, Mr. Eustace also gave private resume reviews to students that signed up during registration.

After the workshops, a buffet luncheon was held for all of the attendees (younger chemists as well as participating company representatives) in the upstairs Esplanade of the Holiday Inn. Immediately following this networking luncheon, these representatives from 12 regional companies made themselves available for greeting and discussing employment with ~120 attending younger chemists. Companies that attended include Strem Chemicals, Inc., AstraZeneca, Novartis Institutes for Biomedical Research, Genzyme, KForce Scientific Staffing, Wyeth, Cubist, Immunogen, Pharm-Eco, Amgen, Degussa, and the German Academic Exchange Service (DAAD). Many beneficial contacts were made through the Fair. One representative from Wyeth said, “We have identified from the applicants an excellent candidate and invited her for an on-site interview. Looking forward to another job fair next year!”

After the Fair, the YCC sent out an electronic survey about the Fair to all participants. The survey results are being used to improve the second annual Career Fair in 2005.

Northeast Student Chemistry Research Conference, NSCRC (April 24)

This year, we had 10 judges at the NSCRC who walked around and questioned students about their posters and research. Among these were Dr. Casey, our very own Chair, Dr. Jean Fuller-Stanley and our Immediate Past-Chair, Dr. John Neumeyer. After the poster session, Dr. Stephen Lippard of MIT gave an excellent Keynote Address entitled “New Fluorescent Sensors to Study Biochemical Zinc and Nitric Oxide and to Monitor Mercury in the Environment.”

Awards were then given out to the students for the best oral and poster presentations. Strem Chemicals Inc. gave a monetary award for the Best Oral Presentation, which went to Christian Ducho of the University of Hamburg. Genzyme gave monetary awards for the Best Poster Presentations. These went to Christopher Dicesare (Tufts University), Supratim Datta (Boston University), and Jamie Ryan (Boston University). The Brauner Undergraduate Book Award went to Elisa Miller of Boston University.

254

Kluwer also donated books as prizes for the conference. These prizes went to William Neeley (MIT), Frank Sischerl (University of Konstanz), Lourdes Pia H. Lopez (MIT), Melanie Schnell (University of Hannover), Nathan Maugel (Merrimack College) and Aaron Gregory Schmidt (Emmanuel College).

Pre-Holiday Networking Event (December 2)

A pre-holiday reception was held at Charley’s Saloon on Newbury Street in Boston. This event, held on December 2 at 7:00pm, attracted 20-25 younger chemists. Appetizers were served and free drinks were awarded to the first ten people to arrive. For the occasion, the YCC printed promotional pamphlets (attached to this report) explaining our organization. We hope to attract new members and officers in the near future.

Next year, we would like to plan more networking events such as brewery tours and bowling outings.

IV. Budget

February Career Symposium $200.00 First Northeast Student Chemistry Career Fair $4000.00 The 6th annual NSCRC (co-sponsored by Education Committee) $5000.00 Website (www.nsycc.org) Address Maintenance $100.00 Networking Events $400.00

Total Expenses $9700.00

This year, the YCC collected $5 registration fees for the NSCRC. We also charged the companies participating in the Career Fair $500 each for their booth space. This offset the costs of these events. The remainder of all funds was received from the Northeastern Section of the American Chemical Society (NESACS).

V. Future Plans

The NSYCC has begun organization of our 5th annual Career Symposium, to be held March 10, 2005 at the Brookline Holiday Inn. The theme of the symposium will be “Making the Transition from School to a Career: Experiences and Advice.” Speakers will include recent graduates and new-comers to their professions in academia, government and industry. They will discuss their experiences and participate in a panel discussion. Our featured speaker for the evening meeting will be Dr. John Fetzer, who will be discussing “Chemistry as a Soft Science.” Copies of his book on career management will be raffled off to younger chemist attendees.

We have also begun plans for the 2nd annual Northeast Student Chemistry Career Fair, to be held March 31, 2005 once again at the Brookline Holiday Inn. We have moved the Fair to an early Thursday evening (3-7pm) to try to accommodate more students and young professionals who can not leave work during the daytime. Dan Eustace of ACS Career Services will once again conduct workshops and resume

255

reviews. The workshops will run concurrently with the job fair this year. We have sent out invitation letters to regional companies and hope to increase corporate participation.

We have also selected the students to participate in the 5th annual exchange between the NESACS-YCC and the GDCh-JCF. This year, we are sending 12 students and 2 representatives to Berlin during the week of April 3, 2005. Applications were accepted and analyzed during November and December 2004. The selected students were notified and plane tickets have been purchased. The students will once again participate in the German student research conference, the Euregionale. They will also be visiting a Max-Planck-Institute as well as universities in Berlin.

Plans for the 7th annual NSCRC are underway. This year, the conference will be held at the Massachusetts Institute of Technology on April 23, 2005.

Beyond April 2005, we plan to have a summer networking event and organize our own National Chemistry Week event. We sent representatives to the NCW events organized by NESACS this year to get ideas for the future. Plans for this will begin after April. Our major goal for 2005 is to foster more interest in subcommittees within the NSYCC. We will need new officers and volunteers to plan events in the new future if we continue to expand. We also want to continue advertising the organization by printing promotional materials such as logo pens and notepads.

256

NSYCC annual activities:

• Northeastern Student Chemistry Research Conference • German Exchange Program Northeastern Section • Northeastern Student Younger Chemists Chemistry Career Fair Committee • Career Symposium • Networking events

For more information But Am I A about the events that we "Younger Chemist"? organize or to join our mailing list, please visit our USUALLY, younger chemists web site: are ACS members under 35. But never fear! Younger chemists are also people not www.nsycc.org yet established in their careers. The criterion for being a member of this group is not age, but experience. SO JOIN US!

257

What is NSYCC? NSCRC: NSCCF:

The Northeastern The Northeastern The Northeastern Section Younger Student Chemistry Student Chemistry Chemists Committee Research Conference, Career Fair affords is part of the Northeastern held every year at the end younger chemists the Section of the American of April, is a day-long event opportunity to discuss Chemical Society (NESACS), featuring student posters employment and network a local section whose and oral presentations, a with representatives from members include chemists keynote speaker, awards, companies in the from Eastern Massachusetts and catered lunch. Northeastern region. and New Hampshire. The Fair also provides attendees with free German workshops on skills Our mission: necessary to attaining a Exchange job. We are devoted to the Program: professional Career advancement of This event is co-organized younger chemists in with the German Symposium: industry, government Chemical Society laboratories, (GDCh) Younger This event provides undergraduate/graduate younger chemists with school and post-doctoral Chemists Committee information on positions. (JCF). Each year, a group current trends in the of younger chemists travel job market, possible across the Atlantic Ocean to careers in chemistry, What do we do? participate in a week-long resume writing, and program which consists of interview skills. We organize a number of visits to local laboratories, The symposium usually Research and Career tours of local companies, consists of a panel presentations at a regional discussion or information related events and aim student research session and is followed by to involve younger chemists conference, networking a monthly NESACS dinner in national and local ACS events and, of course, sight- and research lecture. programs. seeing.

258

ANNUAL REPORT Northeastern Section, ACS

PART III

ANNUAL FINANCIAL REPORT

http://www.nesacs.org

259

PART III - ANNUAL FINANCIAL REPORT

Part A. Statement of Revenues and Expenses Operating Fund Part B. Balance Sheet as of 12/31/04

For financial statements and Balance Sheet, please see report filed online with the National ACS office.

http://www.acs.org

Addendum to Annual Financial Report – 2004

NORTHEASTERN SECTION Attachments to 2004 Financial Report

Line 10 Other Revenues Transfers from Trust Accounts 64,711.09

Line 23 Restricted Funds (including restricted cash) Consolidated Account 1,742,524.00 Esselen Trust 480,604.00 Richards Trust Inc Acct 38,690.00 Norris Trust Inc Acct 7,713.00 Publications Trust Inc Acct 43,818.00 Hill Trust Inc Acct 8,785.00 Levins Award Fund 13,725.00 Brauner Memorial Trust 21,474.00

Total 2,357,333.00

Reconciliation of lines 22 and 32 Inrease in operating cash (Line 22) 2,689.14 Norris National Award paid from Norris Trust -6,922.00 Div/Int income not used for operations 17,014.92 Realized gains from sales 29,650.36 Unrealized gains 190,285.87

Line 32 232,718.29

Support ratios (calculations on p2 are incorrect) Gifts, grants and contributions 59,141.00 Membership fees 53,617.38

260

Exempt function revenues 87,819.23 Unrelated business income (net income is zero) 0.00 Dividend/interest income 81,726.01 Public support ratio 71% Investment income ratio 29%

M E M O R A N D U M

TO: Chairman, Board of Directors Northeastern Section American Chemical Society

FROM: Anthony L. Rosner, Ph.D. Auditor, Northeastern Section American Chemical Society

RE: 2004 Audit Report

DATE: January 6, 2005

------

On January 5, 2005, I examined the accounts and ledgers of the Treasurer of the North- eastern Section of the American Chemical Society. I have found these documents to be generally satisfactory and essentially in line with general accounting practices.

The audit covers the period from January 1, 2004 through December 31, 2004.

______Anthony L. Rosner, Ph.D.

______Date

ACS\AUDIT\05.1/alr

261

ANNUAL REPORT Northeastern Section, ACS

PART IV

CHEMLUMINARY AWARDS

http://www.nesacs.org

262

PART IV - CHEMLUMINARY AWARDS

Award Category: Outstanding Performance by Local Sections

Contact Person: Jean A. Fuller-Stanley Chemistry Department Wellesley College Wellesley, MA 02481

Phone: 781-283-3224 Fax: 781-283-3642 e-mail: [email protected]

Description of Activity/Program:

In 2004 the Northeastern Section continued the tradition of providing a wide variety of programs and activities for its diverse membership and the community at large. In addition to activities that have become a staple of the Section, such as the technical talks, we are continually adding new activities such as career workshops to meet the changing needs of our members at all stages of their career. The Section has been reinvigorated in many areas during 2004; from the open appeal for active participation in the January issue of our newsletter to open acknowledgement of new members and students at monthly meetings. Deliberate attempts were made to inject levity and humor and a spirit of inclusiveness during the Social Hour as well as the beginning of the monthly meetings.

Our speakers, while at times were very technical, provided cutting-edge information and stimulated many engaged discussions among attendees. The topics presented were very varied and as such, in addition to a core group of “regulars,” attendees at the monthly meetings constituted a dynamic rather than a static equilibrium. Topics presented ranged from a medicinal chemistry symposium on New Uses for Old Drugs to a presentation by a patent attorney, Better Chemistry, Better Mousetrap! Patents and What They Can Do For You. Our attendees were very diverse from the retired chemists to academic and industrial chemists and graduate and undergraduate students. We also had good representation of women of all ages and underrepresented minorities. The social hour provided excellent opportunities for networking; the presence of members of K-Force Scientific Staffing Firm and members from NESACS Professional Relations Committee facilitated many fruitful job prospects for members.

The Section also provided many programs for non-members such as Connections to Chemistry targeting High School Chemistry Teachers and numerous awards for high school teachers and high school chemistry students. Our National Chemistry Week activities engaged children of all ages, from 2 to 92, in the interdisciplinary nature of chemistry and of chemistry’s integral role in our Health and Wellness. Additionally, the Section’s Mole Day celebration which started at the NCW kickoff event on October 17th involved over 5000 individuals. In addition to promoting chemistry to the public, the power of 10 was also emphasized and the activities culminated on Mole Day, October 23, with prizes and much celebration.

• NESACS continues to sponsor significant national events in 2004. At the spring 2004 ACS National Meeting, the Section presented the James Flack Norris award in Physical Organic Chemistry to Dr. Poulter. Additionally, the Section renewed its financial commitment for another five years to support the continuation of this important recognition. Other national awards presented by the Section in 2004: Theodore W. Richards Medal to Dr. John Ross for Conspicuous Achievement in Chemistry, Gustavus J. Esselen Award to Dr. James W. Jorgenson for Chemistry in the Public Interest and The James Flack Norris Award for Outstanding Achievement in the Teaching of Chemistry to Dr. Richard N. Zare.

• The NESACS is committed to increasing and maintaining a diverse chemical workforce and continue to demonstrate the Section’s commitment by its renewed financial support for the ACS Scholars program. Additionally, our open invitations to all ACS Scholars within our Section to attend monthly dinner meetings as guests of the Section continues to foster an atmosphere of camaraderie and inclusiveness.

263

• The NESACS Education Committee in conjunction with other sectors such as YCC continue to provide a rich and varied set of activities for chemists at all stages of development, from high school students to high school teachers. These initiatives continue to be extremely proactive, and were very well attended with enthusiastic high school and college students and their teachers. The Committee organized and/or co- sponsored two student research conferences, the Northeast Regional Undergraduate Day and the Connections to Chemistry workshop program for high school chemistry teachers. The Education Committee also jointly organized The Education Night Meeting of the Section; awards were presented for the following: Outstanding teachers and students, summer research scholarships, grants-in-aid for travel to the spring ACS National Meeting. This committee also conducted the Section and National qualifying examinations for the Chemistry Olympiad.

• NESACS NCW kick-off activities started with a ‘bang’. Dr. Jerry Bell, Dr. Jim Golen and Dr. William Dills engaged children of all ages in two separate lectures-demonstrations at Wellesley College on October 17th. Throughout the day, children were engaged in hands-on activities which demonstrated the relation of Chemistry to Health and Wellness. They experimented with such things as: ♥making UV detectors (bracelets) and comparing the effectiveness of sunscreens; ♥isolating iron from Total® cereal; ♥demonstrating proper hand-washing techniques using a Glo Germ kit; ♥demonstrating the importance of insulin to regulate blood sugar; ♥demonstrating how a glucose meter works; ♥demonstrating how dental sealants work and how acidity affects teeth. Free samples of toothbrushes from the Tuft’s University Dental Smile Squad and visits to the Wellesley College Greenhouses to see medicinal plants completed the day’s activities.

• The NESACS was particularly responsive to the needs of its members in 2004 by providing multiple career service programs. Many previous career workshops have been geared primarily at the recent chemistry graduate seeking their first employment. Given the changing nature of the chemical industry with a greater emphasis on interdisciplinary approaches and on biotechnology, many mid-career chemists in our Section became unemployed and many are underemployed. New members were recruited for the Professional Relations Committee and, together with a local scientific employment agency; career service information was provided at all monthly meetings. Additionally, YCC organized a Career and Job Fair as part of the Northeastern Students Research Conference. Information about emerging employment strategies and practices were published in the Nucleus and a career workshop targeting mid-career chemists was held at the September monthly meeting.

To summarize, we can say the year 2004 was very successful in all respects. We remain indebted to our many members and volunteers who gave generously of their time to make these programs and activities possible for our members and the community at large.

Abstract:

In 2004 the Northeastern Section continued the tradition of providing a wide variety of programs and activities for its diverse membership and the community at large. In addition to activities that have become a staple of the Section such as the technical talks, we are continually adding new activities such as career workshops to meet the changing needs of our members at all stages of their career. The Section has been reinvigorated in many areas during 2004 including new fundraising booklets and renewed commitment to the ACS Scholars program, and continuation of financial support for national and local awards in recognition of achievements and service to the chemical profession. Our activities are specifically geared for the engagement of children of all ages, such as NCW activities, Connections to Chemistry for high school teachers and students’ research symposia which continue to attract large numbers.

264

Photograph:

NCW - 2004

265

ACS Local Section Annual Report Part IV ChemLuminary Award Nominations

Award Category: Outstanding Local Section Younger Chemists Committee

Contact Person: Name: Lauren K. Wolf Address: Department of Chemistry Boston University 590 Commonwealth Ave. Boston, MA 02215 Phone: (617) 353-3241 Fax: (617) 353-6466 Email: [email protected]

Description of Activity/Program:

For the Northeastern Section YCC (NSYCC), 2004 was an expansion year. The committee built on its improved organization from 2003 and doubled its attendance at two of its annual activities, the Career Symposium and the Northeast Student Chemistry Research Conference (NSCRC). We also increased our mailing list membership to approximately 150, held a networking social and added a new event, the Northeast Student Chemistry Career Fair (NSCCF).

The Career Fair was our largest undertaking this year. This event featured morning workshops on resume writing and interviewing by ACS Career Services and an afternoon job fair. Twelve companies from the Northeastern region attended and discussed employment with the job-seeking attendees. Several students received interviews/offers as a result of the event. Costs were offset by charging participating companies $500 for their booths.

The NSCRC, held on April 24, 2005 at Boston University, was also a huge success this year. We were able, for the first time, to offer cash prizes as awards for the best student oral and poster presentations. These awards, as well as featured speakers Dr. Stephen Lippard of MIT and Dr. Charles Casey, were responsible for doubling attendance from 2003.

Our annual career symposium, held February 12, 2004 at Boston College, introduced younger chemists to the importance of communication in science. Speakers included a Pulitzer Prize-winning medical writer, a distinguished scientist speaking about chemical education, and a recruiter giving advice on effective communication during interviews. The German Exchange Program 2004, held in Boston this year, also involved more Boston-area younger chemists than any other Exchange organized by NESACS. During the week-long program, the thirteen graduate students from Germany that traveled to Boston, participated in networking events, the NSCRC, the Career Fair, and a tour of Pfizer in Groton, Connecticut, all of which were attended by local YCC members. Visits to the Patriot’s Day Red Sox-Yankees game and a performance of the Symphony also boasted large attendances by NESACS and YCC members.

Abstract

The Northeastern Section YCC (NSYCC) built upon its improved organization from 2003 and doubled its participation in 2004! The NSYCC website (www.nsycc.org) continued to attract more event attendees and members. The NSYCC once again held annual events such as a career symposium featuring the importance of communication in science, a student research conference featuring cash prizes for research presentations, and the German Exchange Program hosting thirteen graduate students from Germany for a week of science and networking in Boston. In addition, the NSYCC held a pre-holiday networking social and organized a new event: the Northeast Student Chemistry Career Fair (NSCCF). This Fair featured resume writing and interviewing workshops by ACS Career Services and a job fair attended by job-seekers and representatives from twelve companies from the Northeastern region.

266

Photo:

Dr. Cassandra Celatka (German Exchange/Career Fair steering committee), Lauren Wolf (YCC Chair), Dr. Amy Tapper (NESACS Chair-Elect), Dr. Charles Casey (ACS President 2004), Ivan Korendovych (YCC Assistant- Chair), Dr. Aida Herrera (YCC Career Chair), Sonia Taktak (YCC Treasurer)

267

ACS Local Section Annual Report Part IV ChemLuminary Award Nominations

Award Category: Outstanding or Creative Local Section Younger Chemists Committee Event

Contact Person: Name: Lauren K. Wolf Address: Department of Chemistry Boston University 590 Commonwealth Ave. Boston, MA 02215 Phone: (617)353-3241 Fax: (617)353-6466 Email: [email protected]

Description of Activity/Program:

The Northeast Student Chemistry Career Fair was the first of its kind ever to be organized by the YCC. Held at the Brookline Holiday Inn on April 23, 2004, it began with a set of morning workshops on resume writing and interviewing. These workshops were hosted by Daniel Eustace of ACS Career Services. Mr. Eustace engaged the ~80 workshop-attending students in discussion about searching for a job and even held a mock interview to illustrate good and bad interviewing behavior. ACS Career Services booklets and materials were also provided to all attendees. During the afternoon job fair, Mr. Eustace also gave private resume reviews to students that signed up during registration.

After the workshops, a buffet luncheon was held for all of the attendees (younger chemists as well as participating company representatives) in the upstairs Esplanade of the Holiday Inn. Immediately following this networking luncheon, these representatives from 12 regional companies made themselves available for greeting and discussing employment with ~120 attending younger chemists. Companies that attended include Strem Chemicals, Inc., AstraZeneca, Novartis Institutes for Biomedical Research, Genzyme, KForce Scientific Staffing, Wyeth, Cubist, Immunogen, Pharm-Eco, Amgen, Degussa, and the German Academic Exchange Service (DAAD). Many beneficial contacts were made through the Fair. Several attendees received interviews/job offers as a result of the event. One representative from Wyeth said, “We have identified from the applicants an excellent candidate and invited her for an on-site interview. Looking forward to another job fair next year!”

Costs for this event were offset by charging each participating company $500 for their booth space. After the Fair, the YCC sent out an electronic survey about the Fair to all participants. The survey results are being used to improve the second annual Career Fair in 2005.

Abstract

In 2004, the Northeastern Section YCC (NSYCC) organized the Northeast Student Chemistry Career Fair (NSCCF), a brand-new event. The Fair, held on Friday, April 23, 2004, featured morning workshops on resume writing and interviewing by ACS Career Services. In the afternoon, ~120 job-seeking attendees met with representatives from twelve different regional companies to discuss employment opportunities. Several attendees received interviews/job offers as a result of the event.

Photo:

268

269

ACS Local Section Annual Report Part IV ChemLuminary Award Nominations

Local Section: Northeastern Section (NESACS)

Award Category: Outstanding On-going NCW Event

Contact Person: Ruth Tanner

Address University of Massachusetts Lowell Chemistry Department, Olney Hall 1 University Avenue Lowell, MA 01854

Phone 978-934-3662 Fax 978-934-3013 E-mail [email protected]

Program Name: Connections to Chemistry Program Chair: Ruth Tanner, University of Massachusetts Lowell Date: October 13, 2004 Site: Burlington High School, Burlington, MA

Number of Participants: 140 High School Chemistry Teachers from 83 High Schools in 5 New England States (Massachusetts, New Hampshire, Connecticut, Rhode Island, Maine).

Synopsis of the Program Connections to Chemistry puts today’s chemistry into the high school classroom and connects the classroom to the educational programs and resources of the American Chemical Society. The program has been offered for four consecutive years and has been scheduled to be presented two weeks before National Chemistry Week in order to highlight the local and national NCW activities as an immediate focus on ACS programs and resources. The program is also designed to encourage the teachers and their students to participate in the NCW activities.

The high school teachers tend to look to the professional teaching organizations for resource materials, including resource people. Most high school chemistry teachers are members of teachers’ organizations such as the National Science Teachers Association, and in New England, the New England Association of Chemistry Teachers (NEACT). The primary focus of these organizations is on educational concerns for secondary education. We would like the teachers to include the ACS chemical education programs and the expertise of our members as important teaching resources. In addition, we would like them to use the ACS programs and publications as important sources for the latest chemical information. Connections to Chemistry gives visibility to the ACS ChemEd programs, directly involves the teachers in the programs, and connects the teachers with chemists from industry and local colleges and universities. NCW activities provide visibility for, and an easily accessible entrée into the ACS programs.

The Connections program uses the theme of NCW in its programming. The program format is as follows: A. Four workshops are offered to showcase the ACS resources for high school chemistry teachers and students. These workshops also showcase the ACS as a broad based resource for chemical information.

The four workshops offered this year were: (a) Cows Eat Grass; People eat Pasta (NCW workshop) Edwin Jahngen, Biochemist, Department of Chemistry, University of Massachusetts Lowell (b) The Real CSI Lab William Hebard, Forensic Chemist, Massachusetts State Police Crime Laboratory (c) Turn Them into Writers, Carolyn Collins Petersen, Science Writer and VP of Loch Ness Productions (d) Bonding and Molecular Graphics, Frank Gorga, Department of Chemical Sciences, Bridgewater State College

270

B. The evening program includes dinner, which gives the teachers time to talk with each other, and also affords us some time to interact with them directly. Following dinner, there is an address that highlights NCW. This year, to highlight the Health and Wellness theme, the address was Vampires, Rockets and the Hot Zone-Confronting Emerging Infectious Diseases, given by Mark Klempner, M.D., Director of the National Biocontainment Laboratories (National Center for Emerging Infectious Diseases and Biodefense) and Associate Provost of Research at Boston University’s Medical Campus.

C. Following the evening address each year, several items are raffled off, including subscriptions to the Journal of Education, affiliate memberships in CHED and NESACS, ACS Chemical Education Division CD’s and software, and several ACS logo products. To conclude the program, participants are given a certificate awarding professional development credits and a year’s subscription to ChemMatters. In addition, all workshop participants receive the November issues of the Journal of Chemical Education, and ChemMatters, which highlight NCW, a past issue of Chemical and Engineering News that has a leading article that highlights the NCW theme, and a tote bag with the ACS logo. To maintain the ACS and local section visibility, the issues of ChemMatters are sent in bulk to NESACS, are labeled Compliments of the Northeastern Section of the American Chemical Society, and are then sent to the workshop participants.

The initial program in 2000 had a registration of 107 teachers. The last two years have seen the program grow to 140, which is the maximum number that can currently be accommodated. This year, in addition to the capacity registration of 140, there was a waiting list of 51, which included people who came but were not registered. This year, registration was closed quite early because the maximum number was reached before the deadline. Currently, the Program Conference Committee is considering ways in which more registrants can be accommodated in the space available and in the current time frame.

The event receives publicity support from the New England Association of Chemistry Teachers, the Massachusetts Association of Science Supervisors, the Massachusetts Association of Science Teachers, Science Teachers Area Resources Swap, the New England Science Teachers, and THE NUCLEUS (the Northeastern Section’s monthly publication). The Program Conference Committee also receives extensive planning and technical program support from volunteers at Burlington High School where the program is held. Program support is also received from members of our own NCW committee, the editorial staff of the Journal of Chemical Education and ChemMatters, members of the Division of Chemical Education (ACS), the Office of High School Science (ACS), and the Editorial Staff of C&E News. Further support comes from chemistry majors at the University of Massachusetts Lowell who serve as laboratory assistants for the program.

In addition to highlighting NCW and the ACS resources, the program also encourages membership in the Division of Chemical Education as a way for the teachers to be directly connected to the Education arm of the organization. This year, Bill Carroll, the then ACS President-Elect for 2004, sent a letter to the teachers at the Connections program proposing a package that included Associate Membership in the ACS Division of Chemical Education (CHED), with enhanced and easier electronic access to high school related materials. If this package, or some form of it, is offered, it would give the high school chemistry teachers a user friendly site to access high school chemistry information on the ACS website including a link to the NCW website.

Planning for the 2005 Connections program will be underway shortly with emphasis on the NCW 2005 theme, The Joy of Toys. We’ll be checking the ACS website for their NCW information

Abstract Connections to Chemistry has been offered for four consecutive years and has been presented two weeks before National Chemistry Week to highlight the local and national NCW activities. The program directly involves the teachers in hands-on workshops, and connects the teachers with chemists from industry, local colleges and universities and the resources of the American Chemical Society. Following dinner, the keynote address continues with the NCW theme. To conclude the program, participants are given ACS publications, which contain articles highlighting the NCW theme, as well as a year’s subscription to ChemMatters.

271

Photograph

272

ACS Local Section Annual Report Part IV ChemLuminary Award Nominations

Local Section: Northeastern Section of the American Chemical Society

Award Category: Outstanding Event for the General Public Using the Yearly Theme Award

Contact Person: Christine Jaworek-Lopes

Address: Emmanuel College 400 The Fenway Boston, MA 02115

Phone: (617)264-7614 Fax: (781) 659-2231 E-mail: [email protected]

Description of the Activity: Name of the Activity/Program: Phyllis A. Brauner Memorial Lecture Date Conducted: Sunday, October 17, 2004 Location of the Event: Wellesley College

Number of Participants: Number of ACS members involved: 50 Approximate size of audience reached: 275

“The Phyllis A. Brauner Memorial Lecture honors the memory of Phyllis A. Brauner (1916-2000) and her steadfast dedication to the chemistry community and to teaching chemistry to the public.”5 Phyllis was an instructor of chemistry at Northeastern University as well as Swarthmore College; she was a professor of chemistry at Simmons College for 34 years. Actively involved in the Northeastern Section of the American Chemical Society, Phyllis was chair of the section in 1974, a Member of the Board of Directors, a Councilor of the section, a Trustee, and the Editor of the Nucleus.

“Over the years, Phyllis organized numerous lectures featuring chemistry educators, such as Hubert Alyea, Jerry Bell, and Dudley Herschbach. The lectures have always been free to the public and have drawn enthusiastic audiences of all ages.”6 In 1986, Phyllis played an integral role in starting a Holiday Lecture Series at the Museum of Science. Professor Bassam Shakhashiri presented the inaugural lecture on December 29, 1986.

“In commemoration of Phyllis’ lifetime of work the Northeastern Section of the ACS has instituted the annual Phyllis A. Brauner Memorial Lecture to be held during National Chemistry Week.”7 On November 4, 2001, the first memorial lecture was held at the Museum of Science in Boston. Professor Bassam Shakhashiri presented a lecture entitled Picasso, Da Vinci, Shakhashiri: Artistry and Chemistry. Approximately 400 individuals attended this free lecture.8 On October 20, 2002, Professor Bassam Shakhashiri regaled audiences at the Museum of Science-Boston with a Phyllis A. Brauner Memorial Lecture entitled “Quest for Chemistry: Moles, Molecules, and Mummies.” Once again, approximately 400 individuals attended this free lecture. The third memorial lecture was held on October 19, 2003 at Wellesley College; approximately 350 individuals attended the lecture-demonstrations performed by Professor Bassam Shakhashiri. Highlights of the lecture included: the methanol cannon and demonstrations of complete vs. incomplete combustion reactions. The fourth memorial lecture was held on October 17, 2004 at Wellesley College; approximately 275 individuals attended the lecture-demonstrations performed by Dr. Jerry Bell of the American Chemical Society, Dr. William Dills of UMASS Dartmouth, and Dr. James Golen of UMASS Dartmouth. Highlights of the lecture included showing that air, a gas, is a substance that takes up space;

5 http://ase.tufts.edu/chemistry/iacobucci/brauner/phyllis.html (last accessed January 27, 2005) 6 http://ase.tufts.edu/chemistry/iacobucci/brauner.lecture.html (last accessed January 27, 2005) 7 http://ase.tufts.edu/chemistry/iacobucci/brauner/lecture.html (last accessed January 27, 2005) 8 Through the generous support of the Lowell Institute, these presentations were free.

273

testing breath for a substance that is acidic and causes limewater to get cloudy, demonstrating the non-flammability of carbon dioxide, and demonstrating some of the properties of hydrogen, oxygen, and hydrogen-oxygen mixtures. Over the years, these captivating lectures were enjoyed by children and adults alike.

For the last four years, the Northeastern Section of the American Chemical Society and either the Museum of Science or Wellesley College has co-sponsored these lectures. These popular lecture demonstrations have been performed to capacity filled lecture halls for the last three years. This event has become a highlight of the Northeastern Section’s National Chemistry Week Kick-off Event.

Abstract of the Activity: The Phyllis A. Brauner Memorial Lectures honors the memory of Phyllis A. Brauner (1916-2000), a dedicated educator in and out of the classroom. For the last four years, the Brauner Memorial Lecture has been a part of the National Chemistry Week Kick-Off Event for the Northeastern Section of the American Chemical Society. Dr. Jerry Bell, Dr. William Dills, and Dr. James Golen or Professor Bassam Shakhashiri has presented to capacity-filled lecture halls at each of these memorial lectures.

Photograph:

Figure 1: Dr. Jim Golen and Dr. Jerry Bell outfit volunteers with goggles. Photograph by: Connie Haddleton

274

ACS Local Section Annual Report Part IV ChemLuminary Award Nominations

Local Section: Northeastern Section of the American Chemical Society

Award Category: Best Student Affiliate Event

Contact Person: Christine Jaworek-Lopes

Address: Emmanuel College 400 The Fenway Boston, MA 02115

Phone: (617) 264-7614 Fax: (781) 659-2231 E-mail: [email protected]

Description of the Activity: Name of the Activity/Program: How big is a mole Dates Conducted: Sunday, October 17, 2004 – Saturday, October, 23, 2004 Location of the Event: Wellesley College, Emmanuel College, Simmons College, Museum of Science Boston

Number of Participants: Number of volunteers: 12 Approximate size of audience reached: 5000

From October 17, 2004 – October 23, 2004 the Simmons College Student Affiliate Chapter educated individuals about the enormity of the mole at a variety of locations including the Wellesley kick-off event (October 17, 2004), Emmanuel and Simmons College (October 18 – October 22, 2004), and at the Museum of Science in Boston (October 23, 2004). This was accomplished by first giving ten individuals a sticker, each numbered one through ten. Each of these ten individuals were given ten additional stickers to give out to ten more people. If any of the “stuck” people returned to the Mole Day table throughout the week they would receive ten stickers as well and information about the mole. To visualize this, a stunning pipe cleaner display was arranged in which each of the original branches were linked together and attached were the people that stickers went out to. One pipe cleaner represented one individual, which made it easy to see the enormity of how many people were reached yet how far from a mole this really was. Over 5000 individuals participated in this event. For partaking in this event, each individual’s number was entered into a free raffle which included various gift certificates and prizes from places around Boston.

This activity was successful in accomplishing the goals of National Chemistry Week particularly in making a positive change in the public's impression of chemistry. Holding this activity at a variety of public venues – three different colleges (one hosting the kick-off event) and at the Museum of Science reached a number of different individuals. Once an individual learned about the mole, this person was able to relay this information to ten more people. A core group of individuals ultimately taught approximately 4500 non-scientists about the mole, a fundamental chemical concept.

Abstract:

The Simmons College Student Affiliate Chapter coordinated the “how big is the mole event?” This community outreach event informed over 5000 participants of the enormity of the mole and the impossibility of reaching a mole’s worth of people. To assist in the visualization of the number of people reached, a stunning pipe cleaner display was arranged.

275

Photograph:

Figure 2: Volunteers pose with pipe cleaner power of 10 display. Photograph by Richard Gurney

276