Journal of Virology

Total Page:16

File Type:pdf, Size:1020Kb

Journal of Virology JOURNAL OF VIROLOGY Volume 67 March 1993 No. 3 ANIMAL VIRUSES Structure of Human Rhinovirus Complexed with Fab Thomas J. Smith, Norman H. 1148-1158 Fragments from a Neutralizing Antibody Olson, R. Holland Cheng, Hansong Liu, Elaine S. Chase, Wai Ming Lee, Donna M. Leippe, Anne G. Mosser, Roland R. Rueckert, and Timothy S. Baker Functional Analysis of the Herpes Simplex Virus UL42 Paul Digard, Connie S. Chow, 1159-1168 Protein Lindsay Pirrit, and Donald M. Coen Integration Is Essential for Efficient Gene Expression of Hiroyuki Sakai, Meiko Kawamura, 1169-1174 Human Immunodeficiency Virus Type 1 Jun-ichi Sakuragi, Sayuri Sakuragi, Riri Shibata, Akinori Ishimoto, Nobumi Ono, Shigeharu Ueda, and Akio Adachi Genetic Heterogeneity in Human T-Cell Dipak K. Dube, Michael P. 1175-1184 Leukemia/Lymphoma Virus Type II Sherman, Nitin K. Saksena, Virginia Bryz-Gornia, Jon Mendelson, Jayne Love, Cheryl B. Arnold, Timothy Spicer, Syamalima Dube, Jordan B. Glaser, Alan E. Williams, Masataka Nishimura, Steven Jacobsen, Jorge F. Ferrer, Noemi del Pino, Sonia Quiruelas, and Bernard J. Poiesz Fusion Formation by the Uncleaved Spike Protein of Murine Fumihiro Taguchi 1195-1202 Coronavirus JHMV Variant cl-2 Marburg Virus Gene 4 Encodes the Virion Membrane Christiane Will, Elke Muhlberger, 1203-1210 Protein, a Type I Transmembrane Glycoprotein Dietmar Linder, Werner Slenczka, Hans-Dieter Klenk, and Heinz Feldmann The Woodchuck Hepatitis Virus X Gene Is Important for Hong-Shu Chen, Shuichi Kaneko, 1218-1226 Establishment of Virus Infection in Woodchucks Rosina Girones, Robert W. Anderson, William E. Hornbuckle, Bud C. Tennant, Paul J. Cote, John L. Gerin, Robert H. Purcell, and Roger H. Miller Simian Immunodeficiency Viruses from Central and Michaela C. Muller, Nitin K. 1227-1235 Western Africa: Evidence for a New Species-Specific Saksena, Eric Nerrienet, Colombe Lentivirus in Tantalus Monkeys Chappey, Vincent M. A. Herve, Jean-Paul Durand, Patricia Legal-Campodonico, Marie-Claude Lang, Jean-Pierre Digoutte, Alain J. Georges, Marie-Claude Georges-Courbot, Pierre Sonigo, and Francoise Barre'-Sinoussi Pseudorabies Virus Protein Homologous to Herpes Simplex Thomas C. Mettenleiter, Armin 1236-1245 Virus Type 1 ICP18.5 Is Necessary for Capsid Maturation Saalmuller, and Frank Weiland WIN 51711-Dependent Mutants of Poliovirus Type 3: Anne G. Mosser and Roland R. 1246-1254 Evidence that Virions Decay after Release from Cells Unless Rueckert Drug Is Present Continued on following page Continued from preceding page Herpes Simplex Virus Type 1-Induced Hemagglutination: Edward Trybala, Bo Svennerholm, 1278-1285 Glycoprotein C Mediates Virus Binding to Erythrocyte Tomas Bergstrom, Sigvard Surface Heparan Sulfate Olofsson, Stig Jeansson, and Jesse L. Goodman Episomal and Integrated Copies of Epstein-Barr Virus Henri-Jacques Delecluse, Sabine 1292-1299 Coexist in Burkitt Lymphoma Cell Lines Bartnizke, Wolfgang Hammerschmidt, Jorn Bullerdiek, and G. W. Bornkamm Characterization of the Protease and Other Products of Fenyong Liu and Bernard Roizman 1300-1309 Amino-Terminus-Proximal Cleavage of the Herpes Simplex Virus 1 UL26 Protein Relevance of Cysteine Residues for Biosynthesis and Georg Wasenauer, Josef Kock, and 1315-1321 Antigenicity of Human Hepatitis B Virus e Protein Hans-Jurgen Schlicht Immediate-Early Transcription over Covalently Joined Cornel Fraefel, Urs V. Wirth, 1328-1333 Genome Ends of Bovine Herpesvirus 1: the circ Gene Bernd Vogt, and Martin Schwyzer Transcriptional Activity and Mutational Analysis of David E. Sleat and Amiya K. 1334-1339 Recombinant Vesicular Stomatitis Virus RNA Polymerase Banerjee Polydnavirus Genome Segment Families in the Ichneumonid Deming Xu and Don Stoltz 1340-1349 Parasitoid Hyposoterfugitivus Mutations in Herpes Simplex Virus Type 1 Genes Encoding Prashant Desai, Neal A. DeLuca, 1357-1364 VP5 and VP23 Abrogate Capsid Formation and Cleavage of Joseph C. Glorioso, and Stanley Replicated DNA Person Expression and Identification of Hepatitis C Virus Arash Grakoui, Czeslaw 1385-1395 Polyprotein Cleavage Products Wychowski, Chao Lin, Stephen M. Feinstone, and Charles M. Rice Characterization of Bunyamwera Virus S RNA That Is Hong Jin and Richard M. Elliott 1396-1404 Transcribed and Replicated by the L Protein Expressed from Recombinant Vaccinia Virus Cooperation of Structural Proteins during Late Events in J. Forstova', N. Krauzewicz, S. 1405-1413 the Life Cycle of Polyomavirus Wallace, A. J. Street, S. M. Dilworth, S. Beard, and B. E. Griffin The El Replication Protein of Bovine Papillomavirus Type 1 Michael R. Lentz, Daniel Pak, Ian 1414-1423 Contains an Extended Nuclear Localization Signal That Mohr, and Michael R. Botchan Includes a p34cdc2 Phosphorylation Site Adult Mouse Kidneys Become Permissive to Acute Isabella A. Atencio, F. F. Shadan, 1424-1432 Polyomavirus Infection and Reactivate Persistent Infections X. J. Zhou, N. D. Vaziri, and in Response to Cellular Damage and Regeneration Luis P. Villarreal Translation of Equine Infectious Anemia Virus Bicistronic Richard Carroll and David Derse 1433-1440 tat-rev mRNA Requires Leaky Ribosome Scanning of the tat CTG Initiation Codon The ULIO Gene of Herpes Simplex Virus 1 Encodes a Novel Joel D. Baines and Bernard 1441-1452 Viral Glycoprotein, gM, Which Is Present in the Virion and Roizman in the Plasma Membrane of Infected Cells Herpes Simplex Virus Type 1 UL46 and UL47 Deletion Yingze Zhang and Jennifer L. C. 1482-1492 Mutants Lack VP11 and VP12 or VP13 and VP14, McKnight Respectively, and Exhibit Altered Viral Thymidine Kinase Expression A Distinct African Lentivirus from Sykes' Monkeys Vanessa M. Hirsch, George A. 1517-1528 Dapolito, Simoy Goldstein, Harold McClure, Peter Emau, Patricia N. Fultz, Mohamed Isahakia, Rhoshel Lenroot, Gerald Myers, and Philip R. Johnson Functional and Defective Components of Avian Endogenous Donald E. Habel, Kirstin L. 1545-1554 Virus Long Terminal Repeat Enhancer Sequences Dohrer, and Kathleen F. Conklin Continued on following page Continued from preceding page Efficient Insertion from an Internal Long Terminal Repeat Antonito T. Panganiban and Katrin 1564-1571 (LTR)-LTR Sequence on a Reticuloendotheliosis Virus J. Talbot Vector Is Imprecise and Cell Specific Asymmetric Resolution of a Parvovirus Palindrome In Vitro Susan F. Cotmore, Jurg P. F. 1579-1589 Nuesch, and Peter Tattersall Influence of Human T-Cell Leukemia Virus Type I tax and Kathleen L. McGuire, Virginia E. 1590-1599 rex on Interleukin-2 Gene Expression Curtiss, Erica L. Larson, and William A. Haseltine Deletion Analysis of the Capsid Protein of Sindbis Virus: Ute Geigenmuller-Gnirke, Hans 1620-1626 Identification of the RNA Binding Region Nitschko, and Sondra Schlesinger Replication of Type 1 Human Immunodeficiency Viruses John Y. H. Kim, Francisco 1658-1662 Containing Linker Substitution Mutations in the -201 to Gonzalez-Scarano, Steven L. -130 Region of the Long Terminal Repeat Zeichner, and James C. Alwine A Monoclonal Antibody Which Blocks Infection with Feline Margaret J. Hosie, Brian J. Willett, 1667-1671 Immunodeficiency Virus Identifies a Possible Non-CD4 Thomas H. Dunsford, Oswald Receptor Jarrett, and James C. Neil Proper Maturation of the Japanese Encephalitis Virus Eiji Konishi and Peter W. Mason 1672-1675 Envelope Glycoprotein Requires Cosynthesis with the Premembrane Protein Disulfide Bond Formation in the Human Immunodeficiency Emmanuel Zazopoulos and William 1676-1680 Virus Type 1 Nef Protein A. Haseltine Purification and Characterization of the DNA-Binding Tatsuya Tsurumi 1681-1687 Activity of the Epstein-Barr Virus DNA Polymerase Accessory Protein BMRF1 Gene Products, as Expressed in Insect Cells by Using the Baculovirus System Cloning and Characterization of Human Astrovirus Suzanne M. Matsui, Jungsuh P. 1712-1715 Immunoreactive Epitopes Kim, Harry B. Greenberg, LaVonne M. Young, Lucinda S. Smith, Terry L. Lewis, John E. Herrmann, Neil R. Blacklow, Kent Dupuis, and Gregory R. Reyes Efficient Analysis of Nonviable Poliovirus Capsid Mutants John Simons, Andrew Rogove, 1734-1738 Nicola Moscufo, Carol Reynolds, and Marie Chow Effect of Number and Position of EBNA-1 Binding Sites in Timothy H. K. Platt, Irina Y. 1739-1745 Epstein-Barr Virus oriP on the Sites of Initiation, Barrier Tcherepanova, and Carl L. Formation, and Termination of Replication Schildkraut VIRUS-CELL INTERACTIONS Structure of a Moloney Murine Leukemia Virus-Virus-Like Antonios Makris, Christos 1286-1291 30 Recombinant: Implications for Transduction of the Patriotis, Susan E. Bear, and c-Ha-ras Proto-Oncogene Philip N. Tsichlis A Subset of Pr659'9 Is Nucleus Associated in Murine Micheal A. Nash, Mercedes K. 1350-1356 Leukemia Virus-Infected Cells Meyer, Glenn L. Decker, and Ralph B. Arlinghaus Low-pH Conformational Changes of Rabies Virus Yves Gaudin, Rob W. H. Ruigrok, 1365-1372 Glycoprotein and Their Role in Membrane Fusion Marcel Knossow, and Anne Flamand Two Mechanisms of Soluble CD4 (sCD4)-Mediated Sherry L. Orloff, M. Susan 1461-1471 Inhibition of Human Immunodeficiency Virus Type 1 Kennedy, Alexia A. Belperron, (HIV-1) Infectivity and Their Relation to Primary HIV-1 Paul J. Maddon, and J. Steven Isolates with Reduced Sensitivity to sCD4 McDougal Characterization of Functional Spl Transcription Factor Pei Zhang, Anneke K. Raney, and 1472-1481 Binding Sites in the Hepatitis B Virus Nucleocapsid Alan McLachlan Promoter Continued on following page Continued from preceding page The Negative Effect of Human Immunodeficiency Virus J. Victor Garcia, John Alfano, and 1511-1516 Type 1 Nef on
Recommended publications
  • Metagenomic Analysis Indicates That Stressors Induce Production of Herpes-Like Viruses in the Coral Porites Compressa
    Metagenomic analysis indicates that stressors induce production of herpes-like viruses in the coral Porites compressa Rebecca L. Vega Thurbera,b,1, Katie L. Barotta, Dana Halla, Hong Liua, Beltran Rodriguez-Muellera, Christelle Desnuesa,c, Robert A. Edwardsa,d,e,f, Matthew Haynesa, Florent E. Anglya, Linda Wegleya, and Forest L. Rohwera,e aDepartment of Biology, dComputational Sciences Research Center, and eCenter for Microbial Sciences, San Diego State University, San Diego, CA 92182; bDepartment of Biological Sciences, Florida International University, 3000 North East 151st, North Miami, FL 33181; cUnite´des Rickettsies, Unite Mixte de Recherche, Centre National de la Recherche Scientifique 6020. Faculte´deMe´ decine de la Timone, 13385 Marseille, France; and fMathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439 Communicated by Baruch S. Blumberg, Fox Chase Cancer Center, Philadelphia, PA, September 11, 2008 (received for review April 25, 2008) During the last several decades corals have been in decline and at least established, an increase in viral particles within dinoflagellates has one-third of all coral species are now threatened with extinction. been hypothesized to be responsible for symbiont loss during Coral disease has been a major contributor to this threat, but little is bleaching (25–27). VLPs also have been identified visually on known about the responsible pathogens. To date most research has several species of scleractinian corals, specifically: Acropora muri- focused on bacterial and fungal diseases; however, viruses may also cata, Porites lobata, Porites lutea, and Porites australiensis (28). Based be important for coral health. Using a combination of empirical viral on morphological characteristics, these VLPs belong to several viral metagenomics and real-time PCR, we show that Porites compressa families including: tailed phages, large filamentous, and small corals contain a suite of eukaryotic viruses, many related to the (30–80 nm) to large (Ͼ100 nm) polyhedral viruses (29).
    [Show full text]
  • Senado Federal
    Reunião de: 06/05/2021 Notas Taquigráficas - Comissões SENADO FEDERAL SENADO FEDERAL SECRETARIA-GERAL DA MESA SECRETARIA DE REGISTRO E REDAÇÃO PARLAMENTAR REUNIÃO 06/05/2021 - 5ª - CPI da Pandemia O SR. PRESIDENTE (Omar Aziz. PSD - AM. Fala da Presidência.) – Bom dia! Havendo número regimental, declaro aberta a 5ª Reunião da Comissão Parlamentar de Inquérito criada pelos Requerimentos 1.371 e 1.372, de 2021, para apurar as ações e omissões do Governo Federal no enfrentamento da pandemia da Covid-19, bem como as cometidas por administradores públicos federais, estaduais e municipais no trato com a coisa pública, durante a vigência da calamidade originada pela pandemia do coronavírus. A presente reunião destina-se às oitivas dos Srs. Marcelo Queiroga, Ministro da Saúde, e Antonio Barra Torres, Presidente da Anvisa. E há ainda requerimentos em pauta para apreciação. Eu quero comunicar: os Requerimentos aprovados nºs 139 a 143, de autoria do Senador Ciro Nogueira, mencionavam informações de Municípios de até 200 mil habitantes. Há um erro material, uma vez que a referência será somente a Municípios a partir de 200 mil habitantes. Nesse sentido, a Secretaria fará a devida retificação nesses requerimentos. Eu vou aguardar a chegada do... Ministro, por favor, desculpa. (Pausa.) Eu vou aguardar a chegada do Relator para que a gente inicie os trabalhos. Pois não? O SR. RANDOLFE RODRIGUES (Bloco Parlamentar Senado Independente/REDE - AP. Pela ordem.) – Estou com o Senador Tasso na linha, ele está pedindo uma questão de ordem antes de iniciar os trabalhos. O SR. PRESIDENTE (Omar Aziz. PSD - AM) – Pois não. O SR.
    [Show full text]
  • Melissaossmanpro.Pdf
    August 19, 2021 Chairman Lipps, Vice Chair Holmes, Ranking Member Russo, and Members of the House Health Committee, thank you for the opportunity to provide proponent testimony on House Bill 248. My family and I are asking that Ohio HB248 be passed in order to protect the individual freedoms we currently have as American citizens. I work in a corporate setting and my husband owns a small business. We have two young daughters who are relying on us to provide for them and protect their rights. I support this bill in hopes that they can grow up with the same liberties we have had. Segregation and discrimination over individual health choices should be taken seriously and passing this bill is key to avoiding those types of issues in the future. I am not a scientist, but I am a mom, a wife, and a daughter who takes the health of my family very seriously. I have done extensive amounts of research on the SARS-COV2 virus and subsequent vaccines. There are also many health experts that provide me with helpful information. I am sure you are receiving many testimonies about the large numbers of vaccine injuries and even deaths that have occurred during this vaccine campaign. Personally, I know two women who have had severe menstrual issues (requiring surgery) that they can connect back to occurring right after the vaccine. My friends’ cousin passed away at only 23 years old from an enlarged heart after receiving the vaccine. The stories go on and on. The point is that no legislation should force my family and I to inject ourselves with substances that have side effects such as this.
    [Show full text]
  • Análise Da Imunogenicidade De Uma Vacina De DNA Codificando Epitopos CD4 Promíscuos E Conservados Do HIV-1 Em Camundongos BALB
    SUSAN PEREIRA RIBEIRO Análise da imunogenicidade de uma vacina de DNA codificando epitopos CD4 promíscuos e conservados do HIV-1 em camundongos BALB/c e transgênicos para moléculas de HLA classe II Tese apresentada à Faculdade de Medicina da Universidade de São Paulo para obtenção do título de Doutor em Ciências Programa de: Alergia e Imunopatologia Orientador: Prof. Dr. Edecio Cunha-Neto São Paulo 2010 SUSAN PEREIRA RIBEIRO Análise da imunogenicidade de uma vacina de DNA codificando epitopos CD4 promíscuos e conservados do HIV-1 em camundongos BALB/c e transgênicos para moléculas de HLA classe II Tese apresentada à Faculdade de Medicina da Universidade de São Paulo para obtenção do título de Doutor em Ciências Programa de: Alergia e Imunopatologia Orientador: Prof. Dr. Edecio Cunha-Neto São Paulo 2010 Dados Internacionais de Catalogação na Publicação (CIP) Preparada pela Biblioteca da Faculdade de Medicina da Universidade de São Paulo reprodução autorizada pelo autor Ribeiro, Susan Pereira Análise da imunogenicidade de uma vacina de DNA codificando epitopos CD4 promíscuos e conservados do HIV-1 em camundongos BALC/c e transgênicos para moléculas de HLA classe II / Susan Pereira Ribeiro. -- São Paulo, 2010. Tese(doutorado)--Faculdade de Medicina da Universidade de São Paulo. Programa de Alergia e Imunopatologia. Orientador: Prof. Dr. Edecio Cunha-Neto. Descritores: 1.Vacinas contra HIV 2.Epitopos de linfócito T 3.Linfócitos T CD4-positivos 4.Camundongos transgênicos 5.Diversidade genética 6.Cobertura vacinal 7.Antígenos HLA 8.Vacinas de DNA 9.HIV 10.AIDS USP/FM/DBD-314/10 Eu gostaria de dedicar esta tese aos meus pais, Cláudio e Rosana, aos meus irmãos Daniel, Vivian, Guilherme e Sarah, à minha filha Helena e à minha sobrinha Carolina, pela presença efetiva em cada passo de minha jornada e pela torcida incansável e incessante.
    [Show full text]
  • On the Biological Success of Viruses
    MI67CH25-Turner ARI 19 June 2013 8:14 V I E E W R S Review in Advance first posted online on June 28, 2013. (Changes may still occur before final publication E online and in print.) I N C N A D V A On the Biological Success of Viruses Brian R. Wasik and Paul E. Turner Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520-8106; email: [email protected], [email protected] Annu. Rev. Microbiol. 2013. 67:519–41 Keywords The Annual Review of Microbiology is online at adaptation, biodiversity, environmental change, evolvability, extinction, micro.annualreviews.org robustness This article’s doi: 10.1146/annurev-micro-090110-102833 Abstract Copyright c 2013 by Annual Reviews. Are viruses more biologically successful than cellular life? Here we exam- All rights reserved ine many ways of gauging biological success, including numerical abun- dance, environmental tolerance, type biodiversity, reproductive potential, and widespread impact on other organisms. We especially focus on suc- cessful ability to evolutionarily adapt in the face of environmental change. Viruses are often challenged by dynamic environments, such as host immune function and evolved resistance as well as abiotic fluctuations in temperature, moisture, and other stressors that reduce virion stability. Despite these chal- lenges, our experimental evolution studies show that viruses can often readily adapt, and novel virus emergence in humans and other hosts is increasingly problematic. We additionally consider whether viruses are advantaged in evolvability—the capacity to evolve—and in avoidance of extinction. On the basis of these different ways of gauging biological success, we conclude that viruses are the most successful inhabitants of the biosphere.
    [Show full text]
  • The Complete Genome of an Endogenous Nimavirus (Nimav-1 Lva) from the Pacific Whiteleg Shrimp Penaeus (Litopenaeus) Vannamei
    G C A T T A C G G C A T genes Article The Complete Genome of an Endogenous Nimavirus (Nimav-1_LVa) From the Pacific Whiteleg Shrimp Penaeus (Litopenaeus) Vannamei Weidong Bao 1,* , Kathy F. J. Tang 2 and Acacia Alcivar-Warren 3,4,* 1 Genetic Information Research Institute, 20380 Town Center Lane, Suite 240, Cupertino, CA 95014, USA 2 Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, 106 Nanjing Road, Qingdao 266071, China; [email protected] 3 Fundación para la Conservation de la Biodiversidad Acuática y Terrestre (FUCOBI), Quito EC1701, Ecuador 4 Environmental Genomics Inc., ONE HEALTH Epigenomics Educational Initiative, P.O. Box 196, Southborough, MA 01772, USA * Correspondence: [email protected] (W.B.); [email protected] (A.A.-W.) Received: 17 December 2019; Accepted: 9 January 2020; Published: 14 January 2020 Abstract: White spot syndrome virus (WSSV), the lone virus of the genus Whispovirus under the family Nimaviridae, is one of the most devastating viruses affecting the shrimp farming industry. Knowledge about this virus, in particular, its evolution history, has been limited, partly due to its large genome and the lack of other closely related free-living viruses for comparative studies. In this study, we reconstructed a full-length endogenous nimavirus consensus genome, Nimav-1_LVa (279,905 bp), in the genome sequence of Penaeus (Litopenaeus) vannamei breed Kehai No. 1 (ASM378908v1). This endogenous virus seemed to insert exclusively into the telomeric pentanucleotide microsatellite (TAACC/GGTTA)n. It encoded 117 putative genes, with some containing introns, such as g012 (inhibitor of apoptosis, IAP), g046 (crustacean hyperglycemic hormone, CHH), g155 (innexin), g158 (Bax inhibitor 1 like).
    [Show full text]
  • JOURNAL of VIROLOGY VOLUME 57 * MARCH 1986 * NUMBER 3 Arnold J
    JOURNAL OF VIROLOGY VOLUME 57 * MARCH 1986 * NUMBER 3 Arnold J. Levine, Editor in Chief Michael B. A. Oldstone, Editor (1988) (1989) Scripps Clinic & Research Foundation Princeton University La Jolla, Calif. Princeton, N.J. Thomas E. Shenk, Editor (1989) David T. Denhardt, Editor (1987) Princeton University University of Western Ontario Princeton, N.J. London, Ontario, Canada Anna Marie Skalka, Editor (1989) Bernard N. Fields, Editor (1988) Hoffmann-La Roche Inc. Harvard Medical School Nutley, N.J. Boston, Mass. Robert A. Weisberg, Editor (1988) Robert M. Krug, Editor (1987) National Institute of Child Health Sloan-Kettering Institute and Human Development New York, N.Y. Bethesda, Md. EDITORIAL BOARD James Alwine (1988) Hidesaburo Hanafusa (1986) Lois K. Miller (1988) Priscilla A. Schaffer (1987) David Baltimore (1987) William S. Hayward (1987) Peter Model (1986) Sondra Schlesinger (1986) Tamar Ben-Porat (1987) Roger Hendrix (1987) Bernard Moss (1986) Manfred Schubert (1988) Kenneth I. Berns (1988) Martin Hirsch (1986) Fred Murphy (1986) June R. Scott (1986) Michael Botchan (1986) John J. Holland (1987) Opendra Narayan (1988) Bart Sefton (1988) Thomas J. Braciale (1988) Ian H. Holmes (1986) Joseph R. Nevins (1988) Charles J. Sherr (1987) Joan Brugge (1988) Robert W. Honess (1986) Nancy G. Nossal (1987) Saul J. Silverstein Barrie J. Carter (1987) Nancy Hopkins (1986) Abner Notkins (1986) (1988) John M. Coffin (1986) Peter M. Howley (1987) J. Thomas Parsons (1986) Patricia G. Spear (1987) Geoffrey M. Cooper (1987) Alice S. Huang (1987) Ulf G. Pettersson (1986) Nat Sternberg (1986) Donald Court (1987) Steve Hughes (1988) Lennart Philipson (1987) Bruce Stillman (1988) Richard Courtney (1986) Tony Hunter (1986) Lewis I.
    [Show full text]
  • Trial Draws Fire After They Have Been Diluted Away
    IN FOCUS NEWS groups, who make the case that Montagnier ETTY G now supports their crazy views,” says John EE/ Moore, an AIDS virologist at Cornell Univer- NAM sity in New York. Montagnier says that AIDS W. MC W. denialist groups misrepresent his thinking. The autism trial enters a new area of contro- versy. The Infectious Disease Society of America have reviewed long-duration antibiotic treat- ments in Lyme disease, and concluded in April that the “inherent risks of long-term antibiotic therapy were not justified by clinical benefit”. Montagnier acknowledges that safety concerns exist, but argues that opposition to long anti- biotic treatments can also be “dogma”. The trials will need to be cleared with the relevant ethics and regulatory bodies, he notes, and will include careful precautions and surveillance. “Expert physicians have learned to avoid side effects and to choose the right regimen,” he says. Another element of the trial is also attract- ing scepticism. Besides screening the children Luc Montagnier, co-discoverer of HIV, is no stranger to controversy. for pathogens with conventional DNA-ampli- fication techniques, the researchers will use a MEDICINE diagnostic test based on the controversial idea championed by the late French scientist Jacques Benveniste, who claimed that water can retain the memory of substances it contained even Trial draws fire after they have been diluted away. Studies have failed to confirm the claim, but Montagnier thinks that the ‘memory’ structures in the water Nobel laureate to test link between autism and infection. can resonate with low-frequency electromag- netic signals, which he hopes can be transmit- BY DECLAN BUTLER Ann Arbor, says that the trials are “not main- ted over the Internet.
    [Show full text]
  • A Novel RNA Virus in the Parasitoid Wasp Lysiphlebus Fabarum: Genomic Structure, Prevalence, and Transmission
    viruses Article A Novel RNA Virus in the Parasitoid Wasp Lysiphlebus fabarum: Genomic Structure, Prevalence, and Transmission 1,2, , 1,2 1,2, Martina N. Lüthi * y , Christoph Vorburger and Alice B. Dennis z 1 Institute of Integrative Biology, ETH Zürich, Universitätstrasse 16, 8092 Zürich, Switzerland; [email protected] (C.V.); [email protected] (A.B.D.) 2 Eawag, Swiss Federal Institute of Aquatic Science and Technology, Überlandstrasse 133, 8600 Dübendorf, Switzerland * Correspondence: [email protected] Current address: Institute of Plant Sciences, University of Bern, Altenbergrain 21, 3013 Bern, Switzerland. y Current address: Institute of Biochemistry and Biology, University of Potsdam, Karl-Liebknecht-Strasse z 24–25, 14476 Potsdam, Germany. Received: 17 November 2019; Accepted: 31 December 2019; Published: 3 January 2020 Abstract: We report on a novel RNA virus infecting the wasp Lysiphlebus fabarum, a parasitoid of aphids. This virus, tentatively named “Lysiphlebus fabarum virus” (LysV), was discovered in transcriptome sequences of wasps from an experimental evolution study in which the parasitoids were allowed to adapt to aphid hosts (Aphis fabae) with or without resistance-conferring endosymbionts. Based on phylogenetic analyses of the viral RNA-dependent RNA polymerase (RdRp), LysV belongs to the Iflaviridae family in the order of the Picornavirales, with the closest known relatives all being parasitoid wasp-infecting viruses. We developed an endpoint PCR and a more sensitive qPCR assay to screen for LysV in field samples and laboratory lines. These screens verified the occurrence of LysV in wild parasitoids and identified the likely wild-source population for lab infections in Western Switzerland. Three viral haplotypes could be distinguished in wild populations, of which two were found in the laboratory.
    [Show full text]
  • Journal of Virology
    JOURNAL OF VIROLOGY Volume 68 November 1994 No. 11 MINIREVIEW Molecular Biology of the Human Immunodeficiency Virus Ramu A. Subbramanian and Eric 6831-6835 Accessory Proteins A. Cohen ANIMAL VIRUSES Monoclonal Antibodies against Influenza Virus PB2 and NP J. Baircena, M. Ochoa, S. de la 6900-6909 Polypeptides Interfere with the Initiation Step of Viral Luna, J. A. Melero, A. Nieto, J. mRNA Synthesis In Vitro Ortin, and A. Portela Low-Affinity E2-Binding Site Mediates Downmodulation of Frank Stubenrauch and Herbert 6959-6966 E2 Transactivation of the Human Papillomavirus Type 8 Pfister Late Promoter Template-Dependent, In Vitro Replication of Rotavirus RNA Dayue Chen, Carl Q.-Y. Zeng, 7030-7039 Melissa J. Wentz, Mario Gorziglia, Mary K. Estes, and Robert F. Ramig Improved Self-Inactivating Retroviral Vectors Derived from Paul Olson, Susan Nelson, and 7060-7066 Spleen Necrosis Virus Ralph Dornburg Isolation of a New Foamy Retrovirus from Orangutans Myra 0. McClure, Paul D. 7124-7130 Bieniasz, Thomas F. Schulz, Ian L. Chrystie, Guy Simpson, Adriano Aguzzi, Julian G. Hoad, Andrew Cunningham, James Kirkwood, and Robin A. Weiss Cell Lines Inducibly Expressing the Adeno-Associated Virus Christina Holscher, Markus Horer, 7169-7177 (AAV) rep Gene: Requirements for Productive Replication Jurgen A. Kleinschmidt, of rep-Negative AAV Mutants Hanswalter Zentgraf, Alexander Burkle, and Regine Heilbronn Role of Flanking E Box Motifs in Human Immunodeficiency S.-H. Ignatius Ou, Leon F. 7188-7199 Virus Type 1 TATA Element Function Garcia-Martinez, Eyvind J. Paulssen, and Richard B. Gaynor Characterization and Molecular Basis of Heterogeneity of Fernando Rodriguez, Carlos 7244-7252 the African Swine Fever Virus Envelope Protein p54 Alcaraz, Adolfo Eiras, Rafael J.
    [Show full text]
  • Response to the COVID-19 Vaccine Effects and the “Protein Shedding” a Growing Number of People Are Asking How Will NANO SOMA
    Response to the COVID-19 vaccine effects and the “protein shedding” A growing number of people are asking how will NANO SOMA help to remove the effects of the injection(s) when people have received them and the effects from the so-called shedding of what is reportedly a spike protein to the uninjected by those who have been injected. As we consider this issue, it is worth recalling the evidence that there are Coronavirus patents held by the Bill & Melinda Gates Foundation in conjunction with DARPA and the WHO from 2018, pre-dating the COVID-19 “Plandemic” and Event 201, the October 2019 planning event that modelled the events that were to be played out in 2020 and beyond. Even more important and profound is this interview by Dr Reiner Fuellmich of Dr David Martin, who explains that there is a COVID patent trail leading back to 2002!!!, and much, much more. A backup of the interview is at this link. In my opinion, this information is profoundly important as we navigate this challenging time. The famous French virologist Luc Montagnier, the 2008 winner of the Nobel Prize in Physiology or Medicine has warned that many will die from the vaccines. Further, Yolande Norris-Clark, a Canadian specialist in women’s health and a doula recently warned of the effects of the shedding upon the hormonal states of uninjected women who come into contact with those who have been injected. Yolande’s video was quickly removed from YouTube and I understand that she has since fled with her family from Canada to Mexico because of the attacks upon her family, I’m speculating because of her uncompromising, informed and articulate stand and message.
    [Show full text]
  • MINUTES of the SIXTH MEETING of the ICTV, SENDAI, 5Th SEPTEMBER 1984
    MINUTES OF THE SIXTH MEETING OF THE ICTV, SENDAI, 5th SEPTEMBER 1984 6/1 - NUMBER OF MEMBERS PRESENT: 19 6/2 - ELECTION OF OFFICERS The following were elected or re-elected: President: F. BROWN Vice-President: H.W. ACKERMANN Committee: B.M. GORMAN Australia D.PETERS Holland J.VLAK Holland Life Member: J.L. MELNICK U.S.A. 6/3 - THE FOLLOWING TAXONOMIC PROPOSALS WERE MADE AND APPROVED FROM THE BACTERIAL VIRUS SUB-COMMITTEE Taxonomic proposal no. 1 The group of bacteriophages with long non-contractile tails should be named Siphoviridae. FROM THE VERTEBRATE VIRUS SUB-COMMITTEE Taxonomic proposal no. 2 The designation of two species a and b of the Influenzavirus genus. Taxonomic proposal no. 3 Creation of the Flaviviridae, a new family of enveloped RNA viruses, based on the present genus Flavivirus. Taxonomic proposal no. 4 That yellow fever virus, strain Asibi, should be the type species of the Flavivirus genus. Taxonomic proposal no. 5 That a genus Arterivirus belonging to the family Togaviridae should be created. Taxonomic proposal no. 6 That equine arteritis virus should be the type species of the genus Arterivirus. Taxonomic proposal no. 7 That a genus Simplexvirus, subfamily Alphaherpesvirinae family Herpesviridae, should be formed. Taxonomic proposal no. 8 That the type species of the Simplexvirus genus should be human herpes simplex virus 1. Taxonomic proposal no. 9 That human herpesvirus 1 and 2 and bovine herpesvirus 2 are recognized members of Simplexvirus genus and that cercopithecine herpesvirus 1 and 2 be candidate species. Taxonomic proposal no. 10 1 That the type species of the Poikilovirus (This name has not been approved and remains unofficial) genus is suid herpesvirus 1 (pseudorabies virus).
    [Show full text]