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Food and Drug Administration, HHS § 172.515

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Food and Drug Administration, HHS § 172.515 Food and Drug Administration, HHS § 172.515 [42 FR 14491, Mar. 15, 1977, as amended at 43 FR 14644, Apr. 7, 1978; 49 FR 10104, Mar. 19, 1984; 54 FR 24897, June 12, 1989; 69 FR 24511, May 4, 2004; 72 FR 10357, Mar. 8, 2007] § 172.515 Synthetic flavoring sub- Amyl heptanoate. stances and adjuvants. Amyl hexanoate. Amyl octanoate. Synthetic flavoring substances and Anisole; methoxybenzene. adjuvants may be safely used in food in Anisyl acetate. accordance with the following condi- Anisyl alcohol; p-methoxybenzyl alcohol. tions. Anisyl butyrate (a) They are used in the minimum Anisyl formate. Anisyl phenylacetate. quantity required to produce their in- Anisyl propionate. tended effect, and otherwise in accord- Beechwood creosote. ance with all the principles of good Benzaldehyde dimethyl acetal. manufacturing practice. Benzaldehyde glyceryl acetal; 2-phenyl-m-di- (b) They consist of one or more of the oxan-5-ol. following, used alone or in combination Benzaldehyde propylene glycol acetal; 4- with flavoring substances and adju- methyl-2-phenyl-m-dioxolane. vants generally recognized as safe in Benzenethiol; thiophenol. Benzoin; 2-hydroxy-2-phenylacetophenone. food, prior-sanctioned for such use, or Benzophenone; diphenylketone. regulated by an appropriate section in Benzyl acetate. this part. Benzyl acetoacetate. Benzyl alcohol. Acetal; acetaldehyde diethyl acetal. Benzyl benzoate. Acetaldehyde phenethyl propyl acetal. Benzyl butyl ether. ′ Acetanisole; 4 -methoxyacetophenone. Benzyl butyrate. Acetophenone; methyl phenyl ketone. Benzyl cinnamate. Allyl anthranilate. Benzyl 2,3–dimethylcrotonate; benzyl methyl Allyl butyrate. tiglate. Allyl cinnamate. Benzyl disulfide; dibenzyl disulfide. Allyl cyclohexaneacetate. Benzyl ethyl ether. Allyl cyclohexanebutyrate. Benzyl formate. Allyl cyclohexanehexanoate. 3-Benzyl-4-heptanone; benzyl dipropyl ke- Allyl cyclohexaneproprionate. tone. Allyl cyclohexanevalerate. Benzyl isobutyrate. Allyl disulfide. Benzyl isovalerate. Allyl 2-ethylbutyrate. Benzyl mercaptan; a-toluenethiol. Allyl hexanoate; allyl caproate. Benzyl methoxyethyl acetal; acetaldehyde Allyl a-ionone; 1-(2,6,6-trimethyl-2-cyclo-hex- benzyl b-methoxyethyl acetal. ene-1-yl)-1,6-heptadiene-3-one. Benzyl phenylacetate. Allyl isothiocyanate; mustard oil. Benzyl propionate. Allyl isovalerate. Benzyl salicylate. Allyl mercaptan; 2-propene-1-thiol. Birch tar oil. Allyl nonanoate. Borneol; d-camphanol. Allyl octanoate. Bornyl acetate. Allyl phenoxyacetate. Bornyl formate. Allyl phenylacetate. Bornyl isovalerate. Allyl propionate. Bornyl valerate. Allyl sorbate; allyl 2,4-hexadienoate. b-Bourbonene; 1,2,3,3a,3bb,4,5,6,6ab,6ba-deca- Allyl sulfide. hydro-la-isopropyl-3aa-methyl-6-meth- Allyl tiglate; allyl trans-2-methyl-2- ylene-cyclobuta [1,2:3,4] dicyclopentene. butenoate. 2-Butanol. Allyl 10-undecenoate. 2-Butanone; methyl ethyl ketone. Ammonium isovalerate. Butter acids. Ammonium sulfide. Butter esters. Amyl alcohol; pentyl alcohol. Butyl acetate. Amyl butyrate. Butyl acetoacetate. a-Amylcinnamaldehyde. Butyl alcohol; 1-butanol. a-Amylcinnamaldehyde dimethyl acetal. Butyl anthranilate. a-Amylcinnamyl acetate. Butyl butyrate. a-Amylcinnamyl alcohol. Butyl butyryllactate; lactic acid, butyl a-Amylcinnamyl formate. ester, butyrate. a-Amylcinnamyl isovalerate. a-Butylcinnamaldehyde. Amyl formate. Butyl cinnamate. 59 VerDate Nov<24>2008 14:38 May 05, 2009 Jkt 217067 PO 00000 Frm 00069 Fmt 8010 Sfmt 8010 Y:\SGML\217067.XXX 217067 cprice-sewell on PRODPC61 with CFR § 172.515 21 CFR Ch. I (4–1–09 Edition) Butyl 2-decenoate. Citronellyl valerate. Butyl ethyl malonate. p-Cresol. Butyl formate. Cuminaldehyde; cuminal; p-isopropyl benz- Butyl heptanoate. aldehyde. Butyl hexanoate. Cyclohexaneacetic acid. Butyl p-hydroxybenzoate. Cyclohexaneethyl acetate. Butyl isobutyrate. Cyclohexyl acetate. Butyl isovalerate. Cyclohexyl anthranilate. Butyl lactate. Cyclohexyl butyrate. Butyl laurate. Cyclohexyl cinnamate. Butyl levulinate. Cyclohexyl formate. Butyl phenylacetate. Cyclohexyl isovalerate. Butyl propionate. Cyclohexyl propionate. Butyl stearate. p-Cymene. Butyl sulfide. g-Decalactone; 4-hydroxy-decanoic acid, g- Butyl 10-undecenoate. lactone. Butyl valerate. g-Decalactone; 5-hydroxy-decanoic acid, d- Butyraldehyde. lactone. Cadinene. Decanal dimethyl acetal. Camphene; 2,2-dimethyl-3-methylene- 1-Decanol; decylic alcohol. norbornane. 2-Decenal. d-Camphor. 3-Decen-2-one; heptylidene acetone. Carvacrol; 2-p-cymenol. Decyl actate. Carvacryl ethyl ether; 2-ethoxy-p-cymene. Decyl butyrate. Carveol; p-mentha-6,8-dien-2-ol. Decyl propionate. 4-Carvomenthenol; 1-p-menthen-4-ol; 4- Dibenzyl ether. terpinenol. 4,4-Dibutyl-g-butyrolactone; 4,4-dibutyl-4-hy- cis Carvone oxide; 1,6-epoxy-p-menth-8-en-2- droxy-butyric acid, g-lactone. one. Dibutyl sebacate. Carvyl acetate. Diethyl malate. Carvyl propionate. Diethyl malonate; ethyl malonate. b-Caryophyllene. Diethyl sebacate. Caryophyllene alcohol. Diethyl succinate. Caryophyllene alcohol acetate. Diethyl tartrate. b-Caryophyllene oxide; 4-12,12-trimethyl-9- 2,5-Diethyltetrahydrofuran. methylene-5-oxatricylo [8.2.0.0 4,6] dode- Dihydrocarveol; 8-p-menthen-2-ol; 6-methyl- cane. 3-isopropenylcyclohexanol. Cedarwood oil alcohols. Dihydrocarvone. Cedarwood oil terpenes. Dihydrocarvyl acetate. 1,4-Cineole. m-Dimethoxybenzene. Cinnamaldehyde ethylene glycol acetal. p-Dimethoxybenzene; dimethyl hydro- Cinnamic acid. quinone. Cinnamyl acetate. 2,4-Dimethylacetophenone. Cinnamyl alcohol; 3-phenyl-2-propen-1-ol. a,a-Dimethylbenzyl isobutyrate; phenyldi- Cinnamyl benzoate. methylcarbinyl isobutyrate. Cinnamyl butyrate. 2,6-Dimethyl-5-heptenal. Cinnamyl cinnamate. 2,6-Dimethyl octanal; isodecylaldehyde. Cinnamyl formate. 3,7-Dimethyl-1-octanol; tetrahydrogeraniol. Cinnamyl isobutyrate. a,a-Dimethylphenethyl acetate; benzyl- Cinnamyl isovalerate. propyl acetate; benzyldimethylcarbinyl ac- Cinnamyl phenylacetate. etate. Cinnamyl propionate. a,a-Dimethylphenethyl alcohol; dimethyl- Citral diethyl acetal; 3,7-dimethyl-2,6-octa- benzyl carbinol. dienal diethyl acetal. a,a-Dimethylphenethyl butyrate; benzyl- Citral dimethyl acetal; 3,7-dimethyl-2,6-octa- dimethylcarbinyl butyrate. dienal dimethyl acetal. a,a-Dimethylphenethyl formate; benzyldi- Citral propylene glycol acetal. methylcarbinyl formate. Citronellal; 3,7-dimethyl-6-octenal; rhodinal. Dimethyl succinate. Citronellol; 3,7-dimethyl-6-octen-1-ol; d-cit- 1,3-Diphenyl-2-propanone; dibenzyl ketone. ronellol. delta-Dodecalactone; 5-hydroxydodecanoic Citronelloxyacetaldehyde. acid, deltalactone. Citronellyl acetate. g-Dodecalactone; 4-hydroxydodecanoic acid g- Citronellyl butyrate. lactone. Citronellyl formate. 2-Dodecenal. Citronellyl isobutyrate. Estragole. Citronellyl phenylacetate. r-Ethoxybenzaldehyde. Citronellyl propionate. Ethyl acetoacetate. 60 VerDate Nov<24>2008 14:38 May 05, 2009 Jkt 217067 PO 00000 Frm 00070 Fmt 8010 Sfmt 8010 Y:\SGML\217067.XXX 217067 cprice-sewell on PRODPC61 with CFR Food and Drug Administration, HHS § 172.515 Ethyl 2-acetyl-3-phenylpropionate; ethyl- Formic acid benzyl acetoacetate. (2-Furyl)-2-propanone; furyl acetone. Ethyl aconitate, mixed esters. 1-Furyl-2-propanone; furyl acetone. Ethyl acrylate. Fusel oil, refined (mixed amyl alcohols). Ethyl r-anisate. Geranyl acetoacetate; trans-3,7-dimethyl-2, 6- Ethyl anthranilate. octadien-1-yl acetoacetate. Ethyl benzoate. Geranyl acetone; 6,10-dimethyl-5,9- Ethyl benzoylacetate. undecadien-2-one. a-Ethylbenzyl butyrate; a-phenylpropyl bu- Geranyl benzoate. tyrate. Geranyl butyrate. Ethyl brassylate; tridecanedioic acid cyclic Geranyl formate. ethylene glycol diester; cyclo 1,13-ethyl- Geranyl hexanoate enedioxytridecan-1,13-dione. Geranyl isobutyrate. 2-Ethylbutyl acetate. Geranyl isovalerate. 2-Ethylbutyraldehyde. Geranyl phenylacetate. 2-Ethylbutyric acid. Geranyl propionate. Ethyl cinnamate. Glucose pentaacetate. Ethyl crotonate; trans-2-butenoic acid ethyl- Guaiacol; μ-methoxyphenol. ester. Guaiacyl acetate; μ-methoxyphenyl acetate. Ethyl cyclohexanepropionate. Guaiacyl phenylacetate. Ethyl decanoate. Guaiene; 1,4-dimethyl-7-isopropenyl-D9,10- 2-Ethylfuran. octahydroazulene. Ethyl 2-furanpropionate. Guaiol acetate; 1,4-dimethyl-7-(a-hydroxy- 4-Ethylguaiacol; 4-ethyl-2-methoxyphenol. isopropyl)-d9,10-octahydroazulene acetate. Ethyl heptanoate. g-Heptalactone; 4-hydroxyheptanoic acid, g- 2-Ethyl-2-heptenal; 2-ethyl-3-butylacrolein. lactone. Ethyl hexanoate. Heptanal; enanthaldehyde. Ethyl isobutyrate. Heptanal dimethyl acetal. Ethyl isovalerate. Heptanal 1,2-glyceryl acetal. Ethyl lactate. 2,3-Heptanedione; acetyl valeryl. Ethyl laurate. 3-Heptanol. Ethyl levulinate. 2-Heptanone; methyl amyl ketone. Ethyl maltol; 2-ethyl-3-hydroxy-4H-pyran-4- 3-Heptanone; ethyl butyl ketone. one. 4-Heptanone; dipropyl ketone. Ethyl 2-methylbutyrate. cis-4-Heptenal; cis-4-hepten-1-al. Ethyl myristate. Heptyl acetate. Ethyl nitrite. Heptyl alcohol; enanthic alcohol. Ethyl nonanoate. Heptyl butyrate. Ethyl 2-nonynoate; ethyl octyne carbonate. Heptyl cinnamate. Ethyl octanoate. Heptyl formate. Ethyl oleate. Heptyl isobutyrate. Ethyl phenylacetate. Heptyl octanoate. Ethyl 4-phenylbutyrate. 1-Hexadecanol; cetyl alcohol. Ethyl 3-phenylglycidate. w-6-Hexadecenlactone; 16-hydroxy-6- Ethyl 3-phenylpropionate; ethyl hydro- hexadecenoic acid, w-lactone; cinnamate. ambrettolide. Ethyl propionate. g-Hexalactone; 4-hydroxyhexanoic acid, g-lac- Ethyl pyruvate. tone; tonkalide. Ethyl salicylate. Hexanal; caproic aldehyde. Ethyl sorbate; ethyl 2,4-hexadienoate. 2,3-Hexanedione; acetyl butyryl. Ethyl tiglate; ethyl trans-2-methyl-2-
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