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schedule at a lance 35th ASA Annual Meeting 8:00 a.m. - 9:00 a.m. AUALECTURE April 10- 13, 2010 Melding Basic Research With Clinical Infertility Needs -A Glass Half Empty Andrology Lab Workshop or Half Full 10-11, 2010 April LarryI. Lipshu/tz, MD ASA Special Symposium Baylor College of Medicine April 10, 2010 (Introduced by Mark Sigman, MD) NEW in 201 0: Basic Science Workshop 9:00 a.m. -9:15 a.m. Distinguished ServiceAward April 10, 2010 9:15 a.m. - 10:45 a.m. SYMPOSIUM I - Lifei n the Womb: FetalDeterm inantsof Men's ASA 351h Annual Meeting Reoroductjve Health Lifetime Determinants of Male Reproductive Health Co-Chairs: John H. Richburg, PhD Robert D. Oates, MD April 10 -13, 2010 Epigenetic Reprogramming of Germ Program Chairs: Kate Loveland, PhD and Mark Sigm��.· MD ' ' Cells and Relevance to Testicular Cancer Sarah Kimmins, PhD Registration fee includes entry into the lectures, one ticket to the McGill University Welcome Reception, a syllabus, and refreshment break. Animal Models for Testicular Cancer *Please note that the all sessions will be held in D.N. Rao Veeramachaneni, DVM, PhD Colorado State University Regency BallroomDEFG unless otherwise noted. Relevance of Human Testis Fetoneonatal Development for Future FRIDAY, APRIL 9, 2010 ... Fertility Hector E. Chemes, MD, PhD Buenos Aires Children'sHospital, 2:00 p.m. - 6:00 p.m. Registration Argentina Location: Regency Ballroom Foyer 10:45 a.m. - 11 :00 a.m. Break - Visit Exhibits SATURDAY, APRIL 10, 2010 Location: Colonnade Salon 7:00 a.m. - 7:00 p.m. Registration 11:00 a.m. - 12:30 p.m. Poster Session I Location: Regency Ballroom Foyer Location: Colonnade Salon 4:00 p.m. - 9:30 p.m. Exhibit Hall Open 12:30 p.m. -2:00 p.m. Lunch (on your own) Location: Colonnade Salon 12:30 p.m. - 2:00 p.m. Women in Andrology Luncheon and Discussion Welcome and Opening Remarks (Not included in 6:00 p.m. - 6:10 p.m. registration fee; tickets required) Location: Windsor 6:10 p.m. - 6:30 p.m. Distinguished Andrologist Award "From Mentee to Mentoring: Preparing Women for Success in Science Careers" 6:30 p.m. - 7:30 p.m. EMILSTEINBERGER MEMORIAL Gayle Slaughter, PhD LECTURE Baylor College of Medicine Insights into Disorders of TestisDevelopment Using Whole CONCURRENT ORALSESSIONS Genome Analysis 2:00 P.M. - 3:30 P.M. ORAL SESSION I - BASIC SCIENCE Andrew Sinclair, PhD Location: Regency Ballroom B Moderators: Ina Dobrinski, DVM, PhD Murdoch Children's Research Greg Bucho/d, PhD Institute, Australia (Introduced by Dolores Lamb, PhD) 2:00 P. M. - 3:30 P.M. ORAL SESSION II - CLINICAL Location: Regency Ballroom C 7:30 p.m. - 7:50 p.m. Updates from NICHD & NIEHS Moderators: John K. Amory, MD Stuart B. Moss, PhD Shayne Louis, MD NICHD 3:30 p.m. - 4:00 p.m. Refreshment Break JerryJ. Heindel, PhD Location: Colonnade Salon NIEHS 4:00 p.m. - 4:45 p.m. LECTURE! 7:50 p.m. - 9:30 p.m. Welcome Reception Erectile Dysfunction: A Red Flag Location: Colonnade Salon forEarly Cardiometabolic Dysfunction Martin Miner, MD SUNDAY, APRIL 11, 2010 Brown University (Introduced by J. Lisa Tenover, MD, PhD) 6:30 a.m. - 8:00 a.m. Past President's Breakfast Location: Woodway LECTURE II 4:45 p.m. - 5:30 p.m. The Progression to Androgen· 7:00 a.m. - 4:00 p.m. Exhibit Hall Open Independent Prostate Cancer Location: Colonnade Salon Robert J. Matusik, PhD 7:00 a.m. - 6:00 p.m. Registration Vanderbilt University Location: Regency Ballroom Foyer (Introduced by Gail S. Prins, PhD) *Locations subjects to change SC 6:30 p.m. - 8:30 p.m. Trainee Forum and Mixer 2:00 p.m. - 3:30 p.m. SYMPOSIUMIll - Fertilityjn Adult Life (All Trainee Travel Awards will be Co-Chairs: Jeffrey J. Lysiak, PhD distributed and celebrated at this Cigdem Tanrikut, MD event) Location: Regency Ballroom ABC Roles of Te sticular MicroRNAs Wei Yan, MD, PhD University of Nevada MONDAY, APRIL 12, 2010 Sperm and Yo ur Natural Marijuana: 7:00 a.m. - 4:00 p.m. Exhibit Hall Open Endocannabinoids, Nicotine and Fertility Location: Colonnade Salon Lani Burkman, PhD University of Buffalo 7:00 a.m. - 6:00 p.m. Registration Location: Regency Ballroom Foyer Phosphorylation Events During Sperm Capacitation Pablo E. Visconti, PhD 8:00 a.m. - 9:00 a.m. WOMENIN AN DROLOGYTUR LEC E University of Massachusetts Epigenetic Changes in Sperm: A Cause of Male Factor Infertility 3:30 p.m. - 4:00 p.m. Break - Visit Exhibits Rebecca Z. Sokol, MD, MPH Location: Colonnade Salon University of Southern California (Introduced by Moira K. O'Bryan, BSc, PhD) 4:00 p.m. - 4:45 p.m. LECTUREIll: Male Reproductive Tract Function 9:00 a.m. - 9:1 5 a.m. Young Andrologist Award Bernard Robaire, PhD McGill University 9:15 a.m. - 10:45 a.m. SYMPOSIUM- II Size Qoes Matter! (Introduced by Joseph Alukal, MD) Growtht jn he Juvenile Co-Chairs: Martin MD,M. Mafzl.J<, PhD 4:45 p.m. - 5:30 p.m. LECTURE IV: Catherine ltman, PhD Translational Andrology: Bridging Bench and Bedside Doublesex-Related Genes Coordinate Christina Wang, MD Somatic and Germ Cell Development UCLA Medical Center in the Mammalian Te stis (Introduced by WilliamJ. Bremner. MD, PhD) David Zarkower, PhD University of Minnesota 5:30 p.m. ASA Business Meeting Outstanding Trainee Investigator and Vitamin A and the Onset of Meiosis Trainee Awards Michael D. Griswold, PhD Washington State University 7:00 p.m. - 11 :OD p.m. Annual Banquet (Not included in registration fee; tickets Normal and Abnormal Pubertal required) Patterns and their Regulation Location: Black Swan Nightclub MaryM. Lee, MD (on property) University of Massachusetts TUESDAY, APRIL 13, 2010 10:45 a.m. - 11 :00 a.m. Break - Visit Exhibits Location: Colonnade Salon 7:00 a.m. - 8:00 a.m. 2010 Program Committee Meeting Location: Westbury 11:00 a.m. - 12:30 p.m. Poster Session II Location: Colonnade Salon 7:30 a.m. -12:15 p.m. Registration Location: Regency Ballroom Foyer 12:30 p.m. - 2:00 p.m. Lunch (on your own) 8:00 a.m. - 9:30 a.m. SY MPOSIUM IV - A in and Male Reproduc ve Health 12:30 p.m. - 2:00 p.m. MENTORINGLUNCHEON g g ti SPONSOREDTHE BY DIVERSITY AN D Co-Chairs: Kirk C. Lo, MD, FRCSC TRAINEE AEfAIRS COMMIUEES Douglas Stocco, PhD (Not included in registration; tickets required) Location: Regency Ballroom C Effects of Aging and Environmental Insults on the Sperm Genome "So You Want to Write a Grant Andrew J. Wyrobek, PhD Application to the NIH: How the Lawrence Berkeley Labs Program Officerand Scientific Review Officer Can Help" Testosterone and the Aging Male Stuart B. Moss, PhD Alvin M. Matsumoto, MD N/CHD University of Washington 12:30 p.m. - 2:00 p.m. Editorial Board Luncheon The Relationship of Paternal Age to Location: Regency BallroomAB Health and Disease in Offspring Susan Harlap, MD New York University 2 SC ea lance 9:30 a.m. - 9:45 a.m. Break - Visit Exhibits Location: Colonnade Salon 9:45 a.m. - 10:45 a.m. INTERNATIONAL LECTURE: Mechanisms of Fertilization - A View Through Gene Manipulated Mice Masaru Okabe, PhD Osaka University (Introduced by Patricia S. Cuasnicu, PhD) 10:45 a.m. - 12:15 p.m. SYMPOSIUMV - Long-Lasting Sex Co-Chairs: Marvin L. Meistrich, PhD Ajay K. Nangia, MBBS The Therapeutic Potential of Germ Stem Cells Amander Clark, PhD University of California, Los Angeles Love and Monogamy: An Endocrine Story C. Sue Carter, PhD University of Illinois at Chicago Long-Lasting S-E·X (Science, Education, Xenogamy) Anna Steinberger, PhD Professor Emerita, UTMS-Houston MEETING ADJOURNED table of contents Schedule at a Glance._. __ • _ -··--··-··-·-··· ·-··- _ 1 President's Welcome_ -·----·-·-···--··-··--·-··-···--- __ 4 Past Presidents ···-··-·---_ ··-···--··--···... - ··-·-- ____ 4 ASA Officers·---·-···-_ -·-· __ -·- ------ -··----- ·-- 5 General Information.. .... _ . _ ··--···--··-...-···-- __ 6 Events & Activities_ . --···"--··--·--..-·- ··-·- 7 Message from the Program Co-Chairs .· -·-..·----····-- _ 8 Emil Steinberger Memorial Lecture Award.·-·-· ..· ···--·- 9 Distinguished Andrologist Award_ ··-- ·--·---.. ·-- 1 0 Distinguished ServiceAward _ ... _ •.. ···-·-- ·-····-- 11 Young Andrologist Award-.•. _.. __.., . ____. ..___ ... _. __12 Outstanding Trainee Investigator Award ...... -·-···"- --12 Thanks to Donors and Sponsors -............ ·----··---· -13 Course Objectives & CME Credit Information-·-·-·-· _14 Schedule of Events.. ·-······- ·····-··.... -... ... -·- ... -·-· _,J 6 Speaker Abstracts._ --· ·· ··-..- ......- ...-- ·- ··----. 21 Poster Session L ....-· -- - ----- ·-....- ·-···· _. _. __. 28 Poster Session 11-·· .. ... --.... - . ---·---...-· --33 Index of Abstract Authors -·······-·-· ______ -·---·-·-39 . · Abstracts Full Text.. .. - --·-···--··--·-·-- 42 Committee Listing ----...·-· ··-··---··--·--·-···---. 81 3 president's welcome I am delighted to invite you to the 34111annual meeting of the American Society of Andrology (ASA) to be held at the Omni Houston Hotel in Houston, Te xas (April 10 - 13, 2010). Houston is at it's best in the springtime when the weather is spectacular and the azaleas are in bloom. While Houston is known to be the home to the largest medical center in the World, the Texas Medical Center, we are also frequently thought of as the home of the NASA manned space flight program. Importantly, Houston is a city to visit, dine in and enjoy. The meeting will be held in the Galleria area close to shopping, ice-skating and restaurants that range from world-class barbeque from Te xMex to Vietnamese/Asian to fine dining. Our distinguished and worthy program co-chairs, Kate Loveland and Mark Sigman (together with the Program Committee), have constructed a broadly fo cused and scientifically stimulating meeting aptly entitled "Lifetime Determinants of Male Reproductive Health". The program includes a number of renowned keynote speakers who will deliver lectures and host symposia and related didactic sessions. At this meeting the first Emil Steinberger, MD Memorial Lecture will be held to honor one of the fo unding fathers and first President of the ASA.