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FISCAL from the Directors
FISCAL From The Directors Dear Colleagues, Advisory Boards for Fiscal 2011 This year marks a decade of strong commitment to technology transfer and economic development at the University of Illinois. It is fitting that this is also the year the Board of Trustees created Urbana the Office of the Vice President for Research and appointed Larry Schook as Interim Vice President, enabling the next step in the evolution of our offices. Bruce Vojak, Chair Van Anderson Advocacy and value creation have been the hallmarks of our Hans Blaschek accomplishments this past year as demonstrated in each Scott Carney initiative and achievement. Proof of concept funding programs Albert Feng on both campuses will help attract licensing partners for our Merle Giles high potential technologies. And joining with other top research Gregory Girolami universities to work with Osage University Partners will help us Gaines Hall realize the financial potential inherent in the preemptive rights Wen-Mei Hwu that are included in most licenses to University start-ups. Jozef Kokini Philip Krein The University of Illinois at Chicago, together with the NIH, Steven Leigh became the first in the world to share patents with Unitaid’s Paul Magelli Medicines Patent Pool, which makes new medicines more Romana Nowak affordable in developing countries. The Urbana campus Michael Philpott developed a unique label license for MIDA boronate technology Jennifer Quirk that enables Sigma-Aldrich and other suppliers to offer its Molly Tracy customers a royalty free license to the University’s intellectual David Weightman property, thus encouraging broad adoption of the technology in Huimin Zhao multiple industries. -
Brain Research Institute. Director. Administrative Files. 1949-1984
http://oac.cdlib.org/findaid/ark:/13030/c8wm1fsv No online items Brain Research Institute. Director. Administrative files. 1949-1984. Finding aid prepared by University Archives staff, 1990 May; finding aid revised by Katharine A. Lawrie, 2013 June; machine-readable finding aid created by Katharine A. Lawrie, 2013 June. UCLA Library Special Collections Room A1713, Charles E. Young Research Library Box 951575 Los Angeles, CA, 90095-1575 (310) 825-4988 [email protected] ©1990 May Brain Research Institute. University Archives Record Series 371 1 Director. Administrative files. 1949-1984. Title: Brain Research Institute. Director. Administrative files. Identifier/Call Number: University Archives Record Series 371 Contributing Institution: UCLA Library Special Collections Language of Material: English Physical Description: 22.8 linear ft.(57 boxes) Date (bulk): Bulk, 1957-1984 Date (inclusive): 1949-1984 Abstract: Record Series 371 contains the administrative files of the directory of UCLA's Brain Research Institute. Creator: Brain Research Institute. Access COLLECTION STORED OFF-SITE AT SRLF: Open for research. Advance notice required for access. Contact the UCLA Library Special Collections Reference Desk for paging information. Publication Rights Copyright of portions of this collection has been assigned to The Regents of the University of California. The UCLA University Archives can grant permission to publish for materials to which it holds the copyright. All requests for permission to publish or quote must be submitted in writing to the UCLA University Archivist. Preferred Citation [Identification of item], Brain Research Institute. Director. Administrative files (University Archives Record Series 371). UCLA Library Special Collections, University Archives. Scope and Content Record Series 371 contains the administrative files of the directory of UCLA's Brain Research Institute. -
From the Cover Contents
July 26, 2011 u vol. 108 u no. 30 u 12187–12560 Cover image: Pictured is a Tasmanian devil (Sarcophilus harrisii), a carnivorous marsupial whose numbers are dwindling due to an infectious facial cancer called Devil Facial Tumor Disease. Webb Miller et al. sequenced the genome of devils from northwest and south- east Tasmania, spanning the range of this threatened species on the Australian island. The authors report that the sequences reveal a worrisome dearth of genetic diversity among devils, suggesting the need for genetically characterized stocks to help breed hardier devils that might be better equipped to fight diseases. See the article by Miller et al. on pages 12348–12353. Image courtesy of Stephan C. Schuster. From the Cover 12348 Decoding the Tasmanian devil genome 12283 Illuminating chromosomal architecture 12295 Symmetry of cultured cells 12319 Caloric restriction and infertility 12366 Genetic diversity among ants Contents COMMENTARIES 12189 Methyl fingerprinting of the nucleosome reveals the molecular mechanism of high-mobility group THIS WEEK IN PNAS nucleosomal-2 (HMGN2) association Catherine A. Musselman and Tatiana G. Kutateladze See companion article on page 12283 12187 In This Issue 12191 Examining the establishment of cellular axes using intrinsic chirality LETTERS (ONLINE ONLY) Jason C. McSheene and Rebecca D. Burdine See companion article on page 12295 E341 Difference between restoring and predicting 3D 12193 Secrets of palm oil biosynthesis revealed structures of the loops in G-protein–coupled Toni Voelker receptors by molecular modeling See companion article on page 12527 Gregory V. Nikiforovich, Christina M. Taylor, Garland R. Marshall, and Thomas J. Baranski E342 Reply to Nikiforovich et al.: Restoration of the loop regions of G-protein–coupled receptors Dahlia A. -
REAL-TIME IMAGING of NITRIC OXIDE (NO) SIGNALS DERIVED from DIFFERENTIALLY TARGETED ENDOTHELIAL NITRIC OXIDE SYNTHASES (Enos) USING GENETICALLY ENCODED BIOSENSORS
T.C. BIRUNI UNIVERSITY INSTITUTE OF GRADUATE EDUCATION DEPARTMENT OF MOLECULAR BIOLOGY AND GENETICS MOLECULAR AND MEDICAL GENETICS GRADUATE PROGRAM REAL-TIME IMAGING OF NITRIC OXIDE (NO) SIGNALS DERIVED FROM DIFFERENTIALLY TARGETED ENDOTHELIAL NITRIC OXIDE SYNTHASES (eNOS) USING GENETICALLY ENCODED BIOSENSORS Mete Emir ÖZGÜRSES ADVISOR Asst. Prof. Dr. Emrah EROĞLU July, 2020 T.C. BIRUNI UNIVERSITY INSTITUTE OF GRADUATE EDUCATION DEPARTMENT OF MOLECULAR BIOLOGY AND GENETICS MOLECULAR AND MEDICAL GENETICS GRADUATE PROGRAM REAL-TIME IMAGING OF NITRIC OXIDE (NO) SIGNALS DERIVED FROM DIFFERENTIALLY TARGETED ENDOTHELIAL NITRIC OXIDE SYNTHASES (eNOS) USING GENETICALLY ENCODED BIOSENSORS Mete Emir ÖZGÜRSES ADVISOR Asst. Prof. Dr. Emrah EROĞLU July, 2020 III DECLARATION I declare that I have designed and performed all experiments in the current study entitled “Real-time imaging of nitric oxide (NO) signals derived from differentially targeted endothelial nitric oxide synthases (eNOS) using genetically encoded biosensors” according to good scientific practices. I obtained all the information contained in this thesis under academic and ethical rules. All the information I have used from secondary literature has been respectively referenced. I also declare that have not violated any patents and copyrights during the preparation and writing of this thesis. Mete Emir Ozgurses IV To all human being, V ACKNOWLEDGEMENT I would like to express my deepest gratitude to everyone who has supported me through this thesis. Firstly, I would like to thank Asst. Prof. Emrah Eroğlu for allowing me to work in his lab. He has guided me throughout the project both by challenging me to be more competent in science and by sharing his instructive ideas. -
SCIENCE and SUSTAINABILITY Impacts of Scientific Knowledge and Technology on Human Society and Its Environment
EM AD IA C S A C I A E PONTIFICIAE ACADEMIAE SCIENTIARVM ACTA 24 I N C T I I F A I R T V N Edited by Werner Arber M O P Joachim von Braun Marcelo Sánchez Sorondo SCIENCE and SUSTAINABILITY Impacts of Scientific Knowledge and Technology on Human Society and Its Environment Plenary Session | 25-29 November 2016 Casina Pio IV | Vatican City LIBRERIA EDITRICE VATICANA VATICAN CITY 2020 Science and Sustainability. Impacts of Scientific Knowledge and Technology on Human Society and its Environment Pontificiae Academiae Scientiarvm Acta 24 The Proceedings of the Plenary Session on Science and Sustainability. Impacts of Scientific Knowledge and Technology on Human Society and its Environment 25-29 November 2016 Edited by Werner Arber Joachim von Braun Marcelo Sánchez Sorondo EX AEDIBVS ACADEMICIS IN CIVITATE VATICANA • MMXX The Pontifical Academy of Sciences Casina Pio IV, 00120 Vatican City Tel: +39 0669883195 • Fax: +39 0669885218 Email: [email protected] • Website: www.pas.va The opinions expressed with absolute freedom during the presentation of the papers of this meeting, although published by the Academy, represent only the points of view of the participants and not those of the Academy. ISBN 978-88-7761-113-0 © Copyright 2020 All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form, or by any means, electronic, mechanical, recording, pho- tocopying or otherwise without the expressed written permission of the publisher. PONTIFICIA ACADEMIA SCIENTIARVM LIBRERIA EDITRICE VATICANA VATICAN CITY The climate is a common good, belonging to all and meant for all. -
Future Flames, Families Check out UIC Campus 5 More on Page 9 UIC MAKES FINAL PRESIDENTIAL LIBRARY LIST 7 MULTIMEDIA MAKEOVER for LECTURE CENTER A
SEPTEMBER 17, 2014 I UIC NEWS I uicnews.uic.edu September 17 2014 VOLUME 34 / NUMBER 4 For the community of the University of Illinois at Chicago uicnews.uic.edu 2 ANDREW MODDRELL REINVENTS THE L.A. RIVERBED OPEN 3 ‘PORTRAITS OF A SOLDIER’ HONORS HOUSE FALLEN MILITARY Future Flames, families check out UIC campus 5 more on page 9 UIC MAKES FINAL PRESIDENTIAL LIBRARY LIST 7 MULTIMEDIA MAKEOVER FOR LECTURE CENTER A INSIDE: CAMPUS NEWS 4 CALENDAR 8 POLICE / DEATHS 10 SPORTS 12 facebook.com/uicnews twitter.com/uicnews youtube.com/uicmedia — Photo: Julie Jaidinger 2 uicnews.uic.edu I UIC NEWS I SEPTEMBER 17, 2014 send profile ideas to Gary Wisby, [email protected] PROFILE ANDREW MODDRELL Reimagining play, reinventing riverbed By Gary Wisby — [email protected] After more than a year’s work on a new $5 million design for Denver’s City Park, Andrew Moddrell is back to the drawing board. Nine months in, the project ran into opposition from a neighborhood group of about 100 people. “They don’t want their park to change,” said Moddrell, assistant professor of ar- chitecture and partner in PORT Archi- tecture and Urbanism. PORT partnered on the project with Denver-based Indie Architecture, run by UIC School of Architecture faculty mem- Andrew Moddrell is collaborating on the design of a Denver park and 51 miles of greenway along the Los Angeles River, now ber Paul Andersen. a concrete channel. “A lot of people in L.A. don’t know they have a river,” says Moddrell, assistant professor of architecture. -
Dr. Salvador Moncada
Sección Gremial Miembro Honorario de la Asociación Hondureña de Neurología, de la Sociedad Hondurena de Epilepsia y de la Federación Centroamericana DR. SALVADOR de Neurología MONCADA El Dr. Salvador Moneada ha de Diciembre de 1944, es, según investigación científica, más de sido electo la revista británica el Scientist, 10 libros científicos, siendo Miembro Honorario de la uno de los 1000 investigadores Doctor en Farmacología y Asociación Hondurena de más citado, de todos los Doctor en Ciencias de la Neurología, de la Sociedad tiempos, por los científicos del Universidad de Londres y Hondurena de Epilepsia y de la mundo, habiendo logrado más teniendo más de 10 doctorados Federación Centroamericana de de 60 premios, incluido el Honoris Causa en Europa, Neurología Premio Príncipe de Asturias Estados Unidos y América Dicho reconocimiento se llevó a 1990 y siendo candidato al Latina. Es el fundador y Direc- cabo durante el Congreso Premio Nobel de Medicina, por tor del Proyecto Cruciforme del Internacional de sus investigaciones, entre las University College London, NEUROCIENCIAS que lleva su cuales están el descubrimiento Londres, Inglaterra. La estatura nombre, realizado en el Hotel del óxido nítrico, de la científica del Dr. Moneada es un Honduras Maya el 18 de agosto tromboxano sintetasa, la fiel ejemplo del legado de de 1997. prostaciclina. nuestros proceres, el Sabio José Cecilio del Valle y Ramón Rosal El Dr. Salvador Moneada nació El Dr. Moneada ha publicado en Tegucigalpa, Honduras, el 3 más de 500 artículos de CURRICULUM VITAE NOMBRE Salvador Moneada LUGAR Y FECHA DE Tegucigalpa, Honduras, 3 de Diciembre, 1944. NACIMIENTO DIRECCIÓN The Cruciform Project, University College London, 140 Tottenham Court Road, London W1P9LN. -
Doukhobor Problem,” 1899-1999
Spirit Wrestling Identity Conflict and the Canadian “Doukhobor Problem,” 1899-1999 By Ashleigh Brienne Androsoff A thesis submitted in conformity with the requirements for the Degree of Doctor of Philosophy, Graduate Department of History, in the University of Toronto © by Ashleigh Brienne Androsoff, 2011 Spirit Wrestling: Identity Conflict and the Canadian “Doukhobor Problem,” 1899-1999 Ashleigh Brienne Androsoff Degree of Doctor of Philosophy, Graduate Department of History, University of Toronto, 2011 ABSTRACT At the end of the nineteenth century, Canada sought “desirable” immigrants to “settle” the Northwest. At the same time, nearly eight thousand members of the Dukhobori (commonly transliterated as “Doukhobors” and translated as “Spirit Wrestlers”) sought refuge from escalating religious persecution perpetrated by Russian church and state authorities. Initially, the Doukhobors’ immigration to Canada in 1899 seemed to satisfy the needs of host and newcomer alike. Both parties soon realized, however, that the Doukhobors’ transition would prove more difficult than anticipated. The Doukhobors’ collective memory of persecution negatively influenced their perception of state interventions in their private affairs. In addition, their expectation that they would be able to preserve their ethno-religious identity on their own terms clashed with Canadian expectations that they would soon integrate into the Canadian mainstream. This study focuses on the historical evolution of the “Doukhobor problem” in Russia and in Canada. It argues that -
Building a “Cross-Roads Discipline” at Mcgill University: a History of Early Experimental Psychology in Postwar Canada
BUILDING A “CROSS-ROADS DISCIPLINE” AT MCGILL UNIVERSITY: A HISTORY OF EARLY EXPERIMENTAL PSYCHOLOGY IN POSTWAR CANADA ERIC OOSENBRUG A dissertation submitted to the Faculty of Graduate Studies in partial fulfillment of the requirements for the degree of Doctor of Philosophy Graduate Program in Psychology. Graduate Program in Psychology York University Toronto, Ontario October 2020 © Eric Oosenbrug, 2020 Abstract This dissertation presents an account of the development of psychology at McGill University from the late nineteenth century through to the early 1960s. The department of psychology at McGill represents an alternative to the traditional American-centered narrative of the cognitive revolution and later emergence of the neurosciences. In the years following World War II, a series of psychological experiments established McGill as among the foremost departments of psychology in North America. This thesis is an institutional history that reconstructs the origins, evolution, and dramatic rise of McGill as a major center for psychological research. The experiments conducted in the early 1950s, in the areas of sensory restriction, motivation, and pain psychology, were transformative in their scope and reach. Central to this story is Donald O. Hebb, author of The Organization of Behavior (1949), who arrived at McGill in 1947 to find the charred remains of a department. I argue that the kind of psychology Hebb established at McGill was different from most departments in North America; this is developed through a number of interwoven storylines focused on the understanding of a particular character of McGill psychology - a distinctive “psychological style” - and its broader historical importance for Canadian psychology, for North American psychology, and for psychology across the globe. -
Masthead (PDF)
PRESIDENT OF Cellular and Developmental Rudolf Jaenisch Physics THE ACADEMY Biology Mary-Claire King Curtis G. Callan, Jr. Ralph J. Cicerone C. David Allis Jasper Rine Anthony Leggett Donald D. Brown Reed B. Wickner Paul C. Martin EDITOR-IN-CHIEF Eric H. Davidson Geology José N. Onuchic Randy Schekman Brigid L. M. Hogan W. G. Ernst Eric N. Olson Physiology and ASSOCIATE EDITORS James P. Kennett Michael Rosbash Pharmacology David Chandler Geophysics David D. Sabatini Richard W. Aldrich Alan Fersht Mark H. Thiemens Gertrud M. Schüpbach Susan G. Amara Jack Halpern Human Environmental David Julius Cellular and Molecular Dolores R. Piperno Sciences Arthur Karlin Neuroscience Solomon H. Snyder Ruth S. DeFries Ramón Latorre Pietro V. De Camilli B. L. Turner II Susan Hanson Peter K. Vogt Richard L. Huganir Plant Biology Susan R. Wessler L. L. Iversen Immunology David Baulcombe Yuh-Nung Jan Peter Cresswell Anthony R. Cashmore SPECIAL FEATURE EDITOR Eve Marder Douglas T. Fearon Maarten J. Chrispeels Steven D. Gaines Jeremy Nathans Tak Wah Mak Enrico Coen Charles F. Stevens Philippa Marrack Joseph R. Ecker EDITORIAL BOARD Thomas C. Südhof William E. Paul Robert Haselkorn Animal, Nutritional, and Joseph S. Takahashi Ralph M. Steinman June B. Nasrallah Applied Microbial Sciences Richard W. Tsien Tadatsugu Taniguchi Plant, Soil, and David L. Denlinger Arthur Weiss Chemistry Microbial Sciences R. Michael Roberts Mathematics Stephen J. Benkovic Roger N. Beachy Linda J. Saif Richard V. Kadison Harry B. Gray James C. Carrington Ryuzo Yanagimachi Robion C. Kirby Michael L. Klein Brian J. Staskawicz Anthropology Raphael D. Levine Medical Genetics, Richard G. Klein Jerrold Meinwald Hematology, and Psychological and Cognitive C. -
Looking Back at the Early Times of Redox Biology Author: Leopold Flohé
Preprints (www.preprints.org) | NOT PEER-REVIEWED | Posted: 26 October 2020 doi:10.20944/preprints202010.0511.v1 1 Title: Looking back at the early times of redox biology Author: Leopold Flohé Affiliations: Dipartimento di Medicina Molecolare, Università degli Studi di Padova, v.le G. Colombo 3, 35121 Padova (Italy) and Departamento de Bioquímica, Universidad de la República, Avda. General Flores 2125, 11800 Montevideo (Uruguay) E-mail: [email protected] Abstract: The beginnings of redox biology are recalled with special emphasis on formation, metabolism and function of reactive oxygen and nitrogen species in mammalian systems. The review covers the early history of heme peroxidases and the metabolism of hydrogen peroxide, the discovery of selenium as integral part of glutathione peroxidases, which expanded the scope of the field to other hydroperoxides including lipid hydroperoxide, the discovery of superoxide dismutases and superoxide radicals in biological systems and their role in host defense, tissue damage, metabolic regulation and signaling, the identification of the endothelial-derived relaxing factor as the nitrogen monoxide radical and its physiological and pathological implications. The article highlights the perception of hydrogen peroxide and other hydroperoxides as signaling molecules, which marks the beginning of the flourishing fields of redox regulation and redox signaling. Final comments describe the development of the redox language. In the 18th and 19th century, it was highly individualized and hard to translate into modern terminology. In the 20th century, the redox language co-developed with the chemical terminology and became clearer. More recently, the introduction and inflationary use of poorly defined terms has unfortunately impaired the understanding of redox events in biological systems. -
NASA National Aeronautics and Space Administration
ACCESSION NUMBER RANGES Accession numbers cited in this Supplement faii within rne following ranges. STAR (N-10000 Series) N87-21846 - N87-23569 IAA (A-10000 Series) A87-35191 - A87-39224 NASA SP-7011(301) AND BIOLOGY A CONTINUING BIBLIOGRAPHY WITH INDEXES (Supplement 301) A selection of annotated references to unclassified reports and journal articles that were introduced into the NASA scientific and technical information system and announced in August 1987 in 9 Scientific and Technical Aerospace Reports (STAR) International Aerospace Abstracts (IAA). Scientific and Technical Information Division 1987 NASA National Aeronautics and Space Administration Washington, DC This supplement is available from the National Technical Information Service (NTIS), Springfield, Virginia 22161, price code A05. INTRODUCTION This Supplement to Aerospace Medicine andBioIogylists 217 reports, articles and other documents announced during August 1987 in Scientific and TechnicalAerospace Reports (STAR)or in International Aerospace Abstracts (IAA). The first issue of the bibliography was published in July 1964. In its subject coverage, Aerospace Medicine andBioIogyconcentrates on the biological, physiolog- ical, psychological, and environmental effects to which man is subjected during and following simulated or actual flight in the Earth’s atmosphere or in interplanetary space. References describing similar effects of biological organisms of lower order are also included. Such related topics as sanitary problems, pharmacology, toxicology, safety and survival, life support systems, exobiology, and person- nel factors receive appropriate attention. In general, emphasis is placed on applied research, but references to fundamental studies and theoretical principles related to experimental development also qualify for inclusion. Each entry in the bibliography consists of a bibliographic citation accompanied in most cases by an abstract.