April 19 - 21 Washington Marriott Wardman Park Washington, DC

ONSITE PROGRAM GUIDE OPEN ACCESS JOURNAL

Getting Your Research Seen Can Be A Challenge. LET JCTS HELP

SUBMIT ARTICLES AT MC.MANUSCRIPTCENTRAL.COM/JCTS

Open access Schedule-at-a-Glance All events are open to Translational Science 2018 attendees unless otherwise noted. *Indicates pre-registration required Please refer to the hotel floor plan on page 48 of the program. **Indicates by invitation only

WEDNESDAY, APRIL 18 LOCATION 8:00 AM - 5:00 PM Challenges and Opportunities in Pediatric Clinical Madison Trials - Investigator Workshop THURSDAY, APRIL 19 LOCATION 7:15 AM - 12:30 PM FDA Tour* Meet in lobby (near entrance to Harry’s Pub) at 7:00 AM 7:45 AM - 9:15 AM Hill Day Advocacy Training* Roosevelt 1 & 2 9:00 AM - 12:30 PM NIH Tour* Meet in lobby (near entrance to Harry’s Pub) at 8:45 AM 9:00 AM - 4:00 PM CTSA Administrators' Meeting* Roosevelt 4 9:15 AM - 1:00 PM Capitol Hill Visits* Transportation provided following Advocacy Training 2:00 PM - 4:00 PM Pre-Doc Directors Meeting Roosevelt 3 2:00 PM - 5:00 PM Mock Study Session* Roosevelt 1 & 2 3:00 PM - 4:00 PM Evaluation SIG Meeting Hoover 3:00 PM - 4:30 PM Research on a Napkin Washington 6 3:00 PM - 5:00 PM Poster Hall Setup (Group A) Exhibit Halls A & B South 5:00 PM - 6:30 PM Opening Plenary Session Marriott Ballroom 6:30 PM - 8:00 PM Opening Poster Hall Reception (Group A) Exhibit Halls A & B South FRIDAY, APRIL 20 LOCATION 7:00 AM - 7:45 AM Poster Hall Viewing & Continental Breakfast (Group A) Exhibit Halls A & B South 8:00 AM - 9:00 AM Plenary Session Marriott Ballroom 9:15 AM - 10:15 AM Concurrent Sessions See page 5 for listings 9:30 AM - 11:00 AM Scholars Networking with Federal Training Partners* Marriott Ballroom 10:30 AM - 11:30 AM Concurrent Sessions See page 6 for listings 10:30 AM - 11:30 AM Top Ten Clinical Research Achievement Awards Delaware A/B 11:00 AM - 1:00 PM Poster Hall Viewing (Group B) Exhibit Halls A & B South 11:45 AM - 12:45 PM PACER SIG Meeting Hoover 11:45 AM - 1:00 PM Top Ten Mentor Lunch** Marriott Ballroom 11:45 AM - 1:00 PM Pre-Doctoral Lunch* Wilson 1:00 PM - 2:00 PM Concurrent Sessions See page 7 for listings 1:00 PM - 2:00 PM Top Ten Clinical Research Achievement Awards Delaware A/B 1:00 PM - 3:15 PM BERD SIG Meeting Hoover 2:15 PM - 3:15 PM CR Forum Concurrent Session: Biomedical Research in the New See page 8 for listings Administration 2:15 PM - 3:15 PM Take It From TED: Using TEDTalk Principles to Improve Your Maryland A/B/C Presentations by the ACTS Education Committee 2:15 PM - 3:15 PM SIG Meetings (CCRCC, Education Administrators, Evaluation, See page 8 for listings Research Operations, Regulatory Science) 2:15 PM - 3:15 PM Poster Hall Viewing (Group B) Exhibit Halls A & B South 2:15 PM - 3:15 PM Speed Mentoring (Pre-and post doc; two sessions will be offered at Marriott Ballroom 2:15 pm and 3:30 pm) 3:30 PM - 4:30 PM Concurrent Sessions See page 8 for listings 3:30 PM - 5:30 PM CR Forum Concurrent Session: Broadly Engaged Team Science Delaware A/B 4:45 PM - 5:45 PM Oral Presentations See page 11 for listings 6:00 PM - 7:00 PM Presentations by Award Winners Roosevelt 1 6:00 PM - 7:30 PM Poster Hall Reception (Group B) Exhibit Halls A & B South SATURDAY, APRIL 21 LOCATION 6:45 AM - 7:30 AM Continental Breakfast Marriott Ballroom Foyer 7:00 AM - 7:30 AM ACTS Annual Member Meeting Maryland 7:45 AM - 8:45 AM Plenary Session Marriott Ballroom 9:00 AM - 10:00 AM Oral Presentations See page 11 for listings 10:15 AM - 11:15 AM Concurrent Sessions See page 9 for listings 10:15 AM - 11:45 AM Leadership Development: Effective Communication and Conflict Roosevelt 1 Management (Workshop) 10:15 AM - 12:30 PM State-of-the-Art Methods for Analyzing Randomized Clinical Trials: Roosevelt 2 Case Studies and Software (Extended Session) 11:30 AM - 12:30 PM Concurrent Sessions See page 10 for listings Translational Science 2018 Award Winners

Edward H. Ahrens, Jr. Distinguished Clinical and Translational Research Translation from Early Clinical Investigator Award: Distinguished Educator Award: Use to Applicability for Widespread Clinical Practice: Daniel J. Rader, MD Lawrence F. “Skip” Brass, MD, PhD Perelman School of at the Perelman School of Medicine at the James G. Krueger, MD, PhD University of University of Pennsylvania The Rockefeller University

Team Science Award: Translation from Clinical Use into AFMR Junior Physician Investigator Public Benefit and Policy: Award: Roy S. Herbst, MD, PhD Yale School of Medicine, MD Cancer Jayme Locke, MD Jennifer Alexander-Brett, MD, PhD Immunotherapy Research University of Alabama at Birmingham Washington University School of Medicine in St. Louis

2017 Research Starter Grants 2017 Research Starter Grants 2017 Research Starter Grants in Translational Medicine and in Translational Medicine and in Translational Medicine and Therapeutics Therapeutics Therapeutics Mark Ebbert, PhD A. Hunter Shain, PhD Qun Wang, PhD Mayo Clinic, Department of University of San Francisco, Iowa State University, Chemical and Neuroscience Department of Dermatology Biological Engineering Department

2 TRANSLATIONAL SCIENCE 2018 Clinical Research Forum Top Ten Clinical Research Achievement Awards

Florian Eichler, MD Timothy McAlindon, DM, MPH Jerry Mendell, MD Massachusetts General Hospital Tufts Medical Center Nationwide Children’s Hospital Gene Therapy Halts Effect of Intra-articular and The Ohio State University Progression of Cerebral ALD Triamcinolone vs Saline on Knee Single-Dose Gene- Cartilage Volume and Pain Replacement Therapy for Herbert Pardes Clinical Research Spinal Muscular Atrophy Excellence Award Distinguished Clinical Research Achievement Award Distinguished Clinical Research Achievement Award

Pablo Tebas, MD Suresh Vedantham, MD David Thaler, MD, Nirali N. Shah, MD, MHSc University of Pennsylvania Washington University in St. PhD, FAHA National Cancer Institute Anti-Zika Virus DNA Vaccine Louis Tufts Medical Center New CAR T-Cell Therapy ATTRACT Trial Concludes Long-Term Outcomes of for Relapsed Leukemia Clot-busting Drugs Do Not Patent Foramen Ovale Patients Prevent Long-Term Blood Closure or Medical Therapy Clot Complications for after Stroke Most Patients

Andrew B. Goldstone, Danish Saleheen, MBBS, PhD Marina Caskey, MD MD, PhD University of Pennsylvania The Rockefeller University University of Pennsylvania The Human Knockout Treatment and Prevention Risk/Benefit Comparison of Project of HIV-1 Infection by Mechanical and Biologic Highly Potent Neutralizing Valve Replacements Monoclonal Antibodies

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 3 Schedule of Events

WEDNESDAY, APRIL 18 3:00 PM – 4:00 PM Evaluation SIG Meeting 8:00 AM – 5:00 PM Hoover Challenges and Opportunities in Pediatric Clinical Trials – Investigator Workshop 3:00 PM – 4:30 PM Madison Research on a Napkin Washington 6

THURSDAY, APRIL 19 3:00 PM – 5:00 PM

7:15 AM – 12:30 PM Poster Hall Setup (Group A) Exhibit Halls A & B South FDA Tour Meet in Marriott Lobby (near Harry’s Pub) at 7:00 AM 5:00 PM – 6:30 PM Pre-registration required Opening Plenary Session 7:45 AM – 9:15 AM Marriott Ballroom Science and technology are moving at an extremely rapid Hill Day Advocacy Training pace, with breakthroughs occurring that have the potential Roosevelt 1 & 2 to transform health and medicine. Dr. Dzau will discuss these Pre-registration required breakthroughs and their implications for health, medicine and society with a focus on translational research. 9:00 AM – 12:30 PM Victor Dzau, MD, of Medicine NIH TOUR 6:30 PM – 8:00 PM Meet in Marriott Lobby (near Harry’s Pub) at 8:45 AM Pre-registration required Opening Poster Hall Reception (Group A) Exhibit Halls A & B South 9:00 AM – 4:00 PM CTSA Administrators’ Meeting FRIDAY, APRIL 20 Roosevelt 4 Pre-registration required 7:00 AM – 7:45 AM 9:15 AM – 1:00 PM Poster Hall Viewing and Continental Breakfast (Group A) Capitol Hill Visits Exhibit Halls A & B South Transportation provided following Advocacy Training Depart from Marriott Lobby (near Harry’s Pub) at 9:15 AM 8:00 AM – 9:00 AM Pre-registration required Plenary Session 2:00 PM – 4:00 PM Marriott Ballroom Pre-Doctoral Directors Meeting Dr. Lifton will discuss the intersection of human genetics and clinical and basic science, highlighting research in Roosevelt 3 hypertension and related areas that have been translated between bench and bedside. 2:00 PM – 5:00 PM Richard P. Lifton, MD, PhD, The Rockefeller University Mock Study Session Roosevelt 1 & 2 Pre-registration required

4 TRANSLATIONAL SCIENCE 2018 9:15 AM - 10:15 AM #DiversityMatters: Biostatisticians’ Contributions to Increasing the Diversity and Success of the Clinical Concurrent Sessions Investigator Workforce AI and Machine Learning in Clinical Research: Roosevelt 4 Experience in Implementation This panel will highlight strategies employed by biostatisticians Roosevelt 1 to enhance recruitment of diverse, STEM-trained individuals into the clinical investigator workforce, and increase the retention This session focuses on experience with advanced intelligence and success of diverse, clinical investigators. (AI) technologies in clinical and research environments, emphasizing lessons learned and how these experiences Presented by: should shape future development of AI and machine learning Emma K.T. Benn, DrPH, MPH, Icahn School of Medicine at in medicine. Mount Sinai Presented by: Felicity Enders, PhD, MPH, Mayo Clinic Robert Kimberly, MD, University of Alabama at Birmingham Sally W. Thurston, PhD, University of Rochester Medical Center Michael Liebman, PhD, IPQ Analytics Doris Rubio, PhD, University of Pittsburgh Beth DiGiullian, MS, Booze Allen Hamilton Session planned by ACTS Session planned by AAMC Team Science to Advance Translational Research CTSA One Health Alliance: Understanding the Benefits Virginia A/B/C of Natural Animal Models of Cancer and Cardiac The session will highlight the characteristics of collaborative Disease teams in advancing translational science, including Roosevelt 2 approaches to enhance team science and lessons from The mission of the CTSA One Health Alliance is to advance our industry teams involved in drug development and discovery. understanding of diseases shared by humans and animals. Presented by: Session will focus on cancer and heart disease. Scott Steele, PhD, University of Rochester Medical Center Presented by: Allan Brasier, MD, University of Wisconsin - Madison School of Carolyn Henry, DVM, MS, DACVIM, University of Missouri Medicine and Public Health College of Veterinary Medicine Husseini Manji, MD, FRCPC, Janssen Pharmaceuticals Kathryn Meurs, DVM, PhD, NC State University College of Session planned by ACTS Veterinary Medicine Session planned by ACTS From Data to Daily Life: Tools for Translating Research and Knowledge into Practice How to Write a Successful Career Development (K) Award Maryland A/B/C This panel will explore how community engaged research must Roosevelt 3 account for the context of research activities when generating, Key requirements of a successful KL2 application, including implementing, and disseminating evidence, practices, and the critical ingredients of a successful KL2 mentorship team projects. and how to avoid common pitfalls made by applicants in unsuccessful KL2 applications. Presented by: Linda Cottler, PhD, MPH, FACE, University Of Florida Clinical Presented by: and Translational Science Institute Kathryn Sandberg, PhD, Georgetown - Howard Universities Sergio Aguilar-Gaxiola, MD, PhD, University of California, Davis Jason G. Umans, MD, PhD, Georgetown - Howard Universities Paris Davis, PhD, MBA, TRCDO/Pastors4PCOR Session planned by ACTS Abel Kho, MD, Northwestern University Session planned by ACTS

9:30 AM – 11:00 AM Scholars Networking with Federal Training Partners Marriott Ballroom Join this session to meet face-to-face with a representative from key federal agencies, such as AHRQ, PCORI, FDA, VA, and NIH. This session allows you to be matched with federal training officials who best match your research interests. Presented by: Kishena Wadhwani, PhD, MPH, AHRQ Diane Bild, MD, MPH, PCORI Yolanda Mock Hawkins, PhD, MBA, FDA Pre-registration required

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 5 Schedule of Events (continued)

10:30 AM – 11:30 AM Development of New Tools for Evaluation of Training Concurrent Sessions Virginia A/B/C Two perspectives: One project aims to enable indexing, Precision Medicine: Challenges and Opportunities to classifying, and discovery of tools in practice across the CTSA; Advance Personalized Medicine another demonstrates leveraging LMS collaboration tools for Roosevelt 1 skill assessment and knowledge checks. This session will explore genomics, deep clinical phenotyping, Presented by: and drug discovery and repurposing in advancing individualized Thomas Perorazio, PhD, University of Michigan School clinical therapeutics, and advancing these insights through of Medicine ultimate approval and adoption in clinical care. Carolyn T. Jones, DNP, MSPH, Ohio State University College Presented by: of Nursing Robert Kimberly, MD, University of Alabama at Birmingham Karen Weavers, MEd, Mayo Clinic Matthew Might, PhD, University of Alabama at Birmingham Becca Gas, MS, Mayo Clinic Jacqueline Corrigan-Curay, JD, MD, CDER Session planned by ACTS Session planned by AAMC A Community-Academic Translational Research and Optimizing the Development and Deployment of Learning Collaborative to Evaluate the Associations Clinical Prediction Algorithms in the Electronic Health Among Biological, Social and Nutritional Status For Record Adolescent Women and their Babies Using Electronic Roosevelt 2 Health Records (EHR) Data A panel will review current practices for working with electronic Maryland A/B/C health records to develop clinical prediction algorithms, and This session describes strategies and infrastructure of a explore approaches to implementation of the algorithms into community-academic collaborative to evaluate biological, electronic workflow. social and nutritional factors affecting adolescent women and Presented by: offspring using EHR Data for hypothesis generation and testing. Susan Perkins, PhD, Indiana University School of Medicine Presented by: Chris Lindsell, PhD, Vanderbilt University Medical Center Milton Eder, PhD, University of Minneasota CTSI Peter Embi, MD, MS, FACP, FACMI, Regenstrief Institute, Inc. Rhonda G. Kost, MD, The Rockefeller University Session planned by ACTS Jonathan N. Tobin, PhD, Clinical Directors Networks, Inc. Daryl Wieland, MD, MS-MI, FACOG, NYC Health and Hospitals/ Rigor and Reproducibility in Translational Science Jacobi Bronx, NY Roosevelt 3 Session planned by ACTS This session will explore some of the current challenges related to rigor and reproducibility in translational science Top Ten Clinical Research Achievement Awards and highlight approaches that have been utilized to address Delaware A/B this issue. This session will feature presentations from this year’s Top Ten Presented by: Clinical Research Achievement Award winners. Kathryn Sandberg, PhD, Georgetown-Howard Universities Presented by: Alex L. Kolodkin, PhD, Johns Hopkins University School of Suresh Vedantham, MD, Washington University School of Medicine Medicine in St. Louis Alison Farrell, PhD, Nature Medicine David Thaler, MD, PhD, FAHA, Tufts Medical Center Session planned by ACTS Andrew Goldstone, MD, PhD, University of Pennsylvania Session planned by CR Forum Successful Career Destinations for Translational Researchers 11:00 AM – 1:00 PM Roosevelt 4 The session will describe several successful career pathways for Poster Hall Setup (Group B) translational researchers that is not the traditional, academic, Exhibit Halls A & B South principal investigator model. Presented by: 11:45 AM – 12:45 PM Anthony Windebank, MD, Mayo Clinic PACER SIG Meeting Richard McFarland PhD, MD, Advanced Regenerative Hoover Manufacturing Institute Alexandra Greenberg-Worisek, PhD, Mayo Clinic College of Medicine and Science 11:45 AM – 1:00 PM Karen Weiss, PhD, LP, Janssen Pharmaceuticals Top Ten Mentor Lunch Session planned by ACTS Marriott Ballroom By Invitation Only

6 TRANSLATIONAL SCIENCE 2018 11:45 AM – 1:00 PM Increasing Effective Research Collaboration: Novel Team Science Approaches Pre-Doctoral Lunch Virginia A/B/C Wilson Session features programs for developing better training and Pre-registration required assessment methods for scholars in team science. Programs identify practical steps for training in specific domains, and 1:00 PM – 3:15 PM assessment methods for measuring successful collaborations. BERD Sig Meeting Presented by: Thomas Perorazio, PhD, Hoover University of Michigan School of Medicine Maritza Salazar Campo, PhD, MSW, University of California, 1:00 PM – 2:00 PM Irvine Concurrent Sessions Judith Olson, PhD, University of California, Irvine Marie K. Norman, PhD, University of Pittsburgh Emerging Role of Digital Medicine in Clinical and Session planned by ACTS Translational Science Roosevelt 1 Real World Experience in Community Engagement: Session will explore current and future approaches to utilize From Clinical Trials to Clinical Care digital medicine for research and clinical applications, Maryland A/B/C highlighting both opportunities and challenges to advance This panel explores real world community engagement these technologies to ultimate approval and adoption. experiences across diverse, minority, senior and disease- Presented by: burdened populations to address how limited inclusion affects Scott Steele, PhD, University of Rochester Medical Center the relevance of research results to clinical practice. Rob Califf, MD, Presented by: Ray Dorsey, MD, MBA, University of Rochester Medical Center Michael Liebman, PhD, IPQ Analytics Session planned by ACTS Kenny Simansky, PhD, Drexel University College of Medicine Allen Glicksman, PhD, Corporation for Aging Serendipity in Science Scott Siegel, PhD, Christiana Care Health System Roosevelt 2 Session planned by ACTS Listen to renowned experts present how serendipity shaped their science and careers. Top Ten Clinical Research Achievement Awards Delaware A/B Presented by: This session will feature presentations from this year’s Top Ten David Center, MD, Boston University Clinical Research Achievement Award winners. Garret Fitzgerald, MD, University of Pennslyvania School of Medicine Presented by: Session planned by AFMR Pablo Tebas, MD, University of Pennsylvania Nirali Shah, MD, MHSc, National Cancer Institute Novel Approaches to Successful Grant Writing Danish Saleheen, MBBS, PhD, University of Pennsylvania Roosevelt 3 Marina Caskey, MD, The Rockefeller University This session will introduce a novel way for teaching and learning Session planned by CR Forum the skill of writing NIH-style research proposals. Attention will also be given to key elements of transitioning from K to R funding. Presented by: Jeffrey Engler, PhD, Council of Graduate Schools Session planned by ACTS

Enabling Entrepreneurship Roosevelt 4 Explore resources available through nine NCATS hubs for training in entrepreneurship and demonstrate the I-Corps methodology developed by the National Science Foundation. Session participants will be engaged in real-world entrepreneurial experiences. Presented by: Stephen Ekker, PhD, Mayo Clinic Molly Wasko, PhD, University of Alabama Birmingham Session planned by ACTS

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 7 Schedule of Events (continued)

2:15 PM – 3:15 PM 3:30 PM – 4:30 PM Biomedical Research in the New Administration Concurrent Sessions Delaware A/B The Changing Regulatory Environment for Clinical Discussion of policies affecting biomedical research and its Research: The Common Rule, Clinical Trials, and funding by Washington insiders. Addressing Regulatory Burden Presented by: Roosevelt 1 Jessica Amrao McNiece, U.S. Senator Richard J. Durbin This session provides an overview of the revised Common Rule, Desiree Mowry, U.S. Senator Roy Blunt new clinical trial regulations, and the 21st Century Cures Act, and Session planned by CR Forum discusses how institutions are navigating this new environment. Presented by: Take It From TED: Using TEDTalk Principles to Improve Jennifer K. Larsen, MD, University of Nebraska Medical Center Your Presentations Heather Pierce, JD, MPH, AAMC Maryland A/B/C Gordon Bernard, MD, Vanderbilt University Medical Center Through both a didactic and activity based learning exercise, Session planned by AAMC participants will come away with the initial tools and framework to develop and deliver an impactful TED Talk. Optimizing Use of REDCap in Research Presented by: Roosevelt 2 Marie Norman, PhD, University of Pittsburgh This session will outline the process of moving a research study Session planned by the ACTS Education Committee database in REDCap from development through to production and live data capture, incorporating perspectives from each SIG Meetings study team member. CCRCC: Roosevelt 2 Presented by: Education Administrators: Wilson A/B/C Jody Ciolino, PhD, Northwestern University Evaluation: Updated Evaluation Guidelines Session planned by ACTS for CTS Program: Roosevelt 3 Research Operations: Virginia A/B/C Utilizing Patient Stakeholders when Designing Clinical Regulatory Science: Roosevelt 1 Research Roosevelt 3 Poster Hall Viewing (Group B) This session will present innovative ways to engage patient stakeholders in clinical research, including design and Exhibit Halls A & B South execution of clinical studies. Speed Mentoring Presented by: Marriott Ballroom Cherry Wontrakool, MD, Emory University Pre- and post-doctoral; two sessions at 2:15 PM and 3:30 PM Pat Furlong, RN, BSN, Parent Project Muscular Dystrophy Yvonne Lin, MD, MS, Genentech-Roche Translational Science 2018 will be hosting an hour-long speed mentoring session with two time options for attendance (2:15 Session planned by AFMR PM and 3:30 PM). Speed mentoring allows mentees to connect with five senior scientists over the course of an hour for mini- Using Big Data and Network Science to Measure CTSA discussions. Speed mentoring is a great way to expand your Impact network, ask pointed questions, get advice about finding Roosevelt 4 resources, seek candid feedback, and chat informally about This session features a unique data infrastructure for evaluating life in research with people who know the ropes. the work of CTSAs, focusing on trainee career outcomes and a network science initiative to study faculty collaborations and interdisciplinary team science. Presented by: Jason Owen-Smith, PhD, MBA, University of Michigan School of Medicine Raffaele Vacca, PhD, University of Florida Session planned by ACTS

8 TRANSLATIONAL SCIENCE 2018 How to Write a Successful F-Award SATURDAY, APRIL 21 Virginia A/B/C Participants will learn how to put together a successful 6:45 AM - 7:30 AM application for a NIH F-award to support their pre-doctoral research as a PhD or MD-PhD student or as a postdoctoral fellow. Continental Breakfast Presented by: Marriott Ballroom Foyer Linda M McManus, PhD, University of Texas Health Science Center San Antonio 7:00 AM – 7:30 AM Stephen Ekker, PhD, Mayo Clinic ACTS Annual Member Meeting Session planned by ACTS Maryland Eliminating Disparities by Improving Health Outcomes: Case Studies in Optimal Experiences Translating 7:45 AM – 8:45 AM Science into Practice Plenary Session Maryland A/B/C Marriott Ballroom Learn from the success stories of experts in clinical and The Closing Plenary session will explore the issue of scientific translational research with minorities and underrepresented communication, focusing on communicating your science to a populations. lay audience. Two expert panelists will share their wisdom and Presented by: experience of best practices. Iuliana Shapira, MD, SUNY Downstate Medical Center Robert P. Kimberly, MD, University of Alabama at Birmingham Eliseo J. Perez-Stable, MD, NIMHHD Karen Kaplan, Los Angeles Times Carla Boutin-Foster, MD, SUNY Downstate Medical Center Alan Leshner, MD, American Association for the Advancement Session planned by ACTS of Science (AAAS)

3:30 PM – 5:30 PM 9:00 AM – 10:00 AM Broadly Engaged Team Science: Panel on Guidelines Concurrent Distinguished Pre- and Post-Doctoral and Implementation at Academic Health Centers Oral Presentations Delaware A/B See pages 10 - 12 for full schedule of speakers and rooms. The practice of broadly engaged team science provides opportunities and obstacles for Academic Health Centers. This session will discuss what some of the barriers and opportunities 10:15 AM – 11:15 AM are, and provide best practice examples. Concurrent Sessions Presented by: Harry Selker, MD, MSPH, Tufts University Improving Research Mentoring Relationships from Joe V. Selby, MD, PCORI the Middle Mary Sue Coleman, MD, American Association of Universities Roosevelt 3 Elaine Gallin, PhD, QE Philanthropic Advisors CTSA K-scholars and T-trainees serve roles as research mentors Session planned by CR Forum and mentees. Through small group activities, case study discussions, and links to online resources, participants will reflect on dual roles. 4:45 PM – 5:45 PM Presented by: Concurrent Distinguished Pre- and Post-Doctoral Christine Pfund, PhD, University of Wisconsin Oral Presentations Christine Sorkness, PharmD, University of Wisconsin See pages 10 - 12 for full schedule of speakers and rooms. Session planned by ACTS

Dissemination and Implementation of Research: 6:00 PM – 7:00 PM Bridging Research to Practice and Policies AFMR Award Presentations Symposium Roosevelt 4 Roosevelt 1 Learn from the experts about the complex fit between evidence and evidence-based interventions, and the diversity of 6:00 PM – 7:30 PM community and clinical settings where health and health care is delivered. Poster Hall Reception (Group B) Presented by: Exhibit Halls A & B South Kathleen Stevens, RN, EdD, FAAN, University of Texas Health Science Center San Antonio David Chambers, DPhil, NCI Session planned by ACTS

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 9 Schedule of Events (continued)

Innovations in Academic-Industry Partnerships 11:30 AM – 12:30 PM Roosevelt 5 Concurrent Sessions Academics often collaborate with industry to develop therapeutics and devices; however, different goals, processes, Broad Career Development Plans for Clinical and and constraints exist. This session highlights these unique Translational Scientists aspects in support of developing a more effective partnership. Roosevelt 3 Presented by: New scientists may not fit in the paradigm of traditional Michael Schivo, MD, MAS, University of California, Davis academics. This session aims to illustrate broad career Michael Liebman, PhD, IPQ Analytics development plans for today’s clinical and translational Nicholas Sarlis, MD, PhD, FACP, Sellas Life Sciences Group scientist trainees. Session planned by AFMR Presented by: Michael Schivo, MD, MAS, University of California, Davis Community Health Needs Assessments: Emma Meagher, MD, University of Pennsylvania School of Catalyst for Community Engaged Research? Medicine Maryland A/B/C Fredrick J. Meyers, MD, MACP, University of California, Davis Community Health Needs Assessments (CHNA) provide Session planned by AFMR academic health centers opportunities to engage communities. This panel explores using a CHNA to create a The Role for Translational Science to Address the social contract, including planning clinical research activities. Opioid Crisis Presented by: Roosevelt 4 Milton Eder, PhD, University of Minnesota CTSI This session will focus on the opioid crisis, considering strategies Paula Fleisher, MA, University of California, San Francisco to more effectively treat pain, limit inappropriate prescribing, Michelle Lyn, MBA, MHA, Duke University and facilitate the return or disposal of unused opioids in the community. Philip Alberti, PhD, AAMC Session planned by ACTS Presented by: Michael Kurilla, MD, PhD, NCATS 10:15 AM – 11:45 AM Carlos Blanco, MD, PhD, NIDA Chad Brummett, MD, University of Michigan School of Medicine Leadership Development: Effective Communication Session planned by ACTS and Conflict Management Roosevelt 1 Biostatistics and Data Science: Identifying their Participants will learn and practice specific conflict- Complementary Roles in Clinical and Translational management behaviors encountered in collaborative pursuits Research that are associated with effective academic leaders. Roosevelt 5 Presented by: The speakers (a clinician/data scientist and biostatistician/ Irena Tartakovsky, MD, MS, AAMC data scientist) will share, through personal examples, their perspectives and experiences collaborating with investigators Constance M. Filling, EdD, AAMC trained in biostatistics, informatics, computer science, and Deborah L. Helitzer, ScD, Arizona State University other quantitative fields. Session planned by AAMC Presented by: Nichole Carlson, UPhD, University of Colorado at Denver 10:15 AM – 12:30 PM Tell Bennett, MD, University of Colorado Department of State-of-the-Art Methods for Analyzing Randomized Pediatrics Clinical Trials: Case Studies and Software Rickey Carter, PhD, Mayo Clinic Roosevelt 2 Session planned by ACTS This session presents two methods for improving the analysis of randomized trials: covariate adjustment to increase precision and reduce bias; sensitivity analysis for reporting results in the presence of missing outcome data. Presented by: Daniel Oscar Scharfstein, ScD, John Hopkins Michael Aaron Rosenblum, PhD, John Hopkins Presented by ACTS

10 TRANSLATIONAL SCIENCE 2018 Concurrent Distinguished Pre-Doctoral and Post-Doctoral Oral Presentations

Friday, April 20 | 4:45 PM – 5:45 PM

Maryland A/B/C Roosevelt 2

A Patient-Friendly Research Participant Registry: The UT Mucoidal Pseudomonas Aeruginosa Infection is Southwestern Volunteer Research Participant Registry Associated with Regional Inflammation in the Cystic Kathleen Wilkinson, UT Southwestern Medical Center Fibrosis Lung Sankalp Malhotra, The Ohio State University Reproducibility of Electronic Health Record Research Data Requests Identifying the Role and Immunobiological Ram Gouripeddi, The University of Utah School of Medicine Mechanisms of Fli-1 Mediated Pathogenicity in Graft- versus-Host Disease Development of an Instrument to Identify Factors Steven Schutt, Medical University of South Carolina Influencing Point of Care Recruitment in Primary Care Settings: A Pilot Study at University of Utah Health Antibiotics, Early-Life Microbiota, and Susceptibility to Teresa Taft, The University of Utah School of Medicine Asthmatic Disease Timothy C. Borbet, NYU - H+H Clinical and Translational Science Exposure to Violence Correlated to Elevated Institute Immunoglobulin E and Epstein Barr Virus Levels in African American Young Adults Regulation of Retinal Protein O-GlcNAcylation by Latifa Jackson, Georgetown - Howard Universities Angiotensin-(1-7) and cAMP Sadie Dierschke, Penn State Clinical and Translational Science Prediction of 90-Day Readmission among Kidney Institute Transplant Recipients Using Natural Language Processing Comparing Metabolic Labeling of Human Tumors at Michael Arenson, Emory University Different Anatomic Sites Divya Bezwada, University of Texas Southwestern Medical Center Dallas

Roosevelt 1 Roosevelt 3

Use of Forced Air Warming Devices to Induce Characterizing Specialized Pro-Resolving Lipid Feverrange Hyperthermia in Critically Ill Septic Patients Mediators and Synthesis Pathways in Veterans with Anne Meredith Drewry, Washington University in St. Louis, Peripheral Artery Disease Institute Of Clinical and Translational Sciences Joel Ramirez, University Of California, San Francisco

Screening for Multi-Drug Resistant Gram-Negative A Novel Multi-Photon Microscopy Method for Bacilli in Critically Ill Burn Patients Predicts Subsequent Neuronavigation in Deep Brain Stimulation Surgery Bacterial Etiology of Infection Nicholas Matthew George, University of Colorado at Denver Anne Monica Lachiewicz, University of North Carolina School of Medicine Sexual Dimorphism in a Mouse Model of Syndromic Thoracic Aortic Aneurysm Kidney Transplantation: A High Risk State for Zheying Chen, University of Kentucky Center for Clinical and Prediabetes and Diabetes Translational Science Francis Tinney, Jr., University of Texas Health Science Center San Antonio Augmenting Perception Through Direct Electrical Stimulation of Adult Somatosensory Cortex Rapidly Resolving Acute Respiratory Distress Yohannes Ghenbot, University of Pennsylvania School of Syndrome: A Secondary Analysis of the ARDS Network Medicine Randomized Controlled Trials Edward J. Schenck, Weill Cornell Medicine MicroRNA-451: A Potential Key Player in the Development of Diabetic Nephropathy in an Insulin Low Cholesterol Efflux Capacity and Abnormal Resistant Mouse Model Lipoprotein Particles in Youth with Type 1 Diabetes Maurice B. Fluitt, Georgetown - Howard Universities Evgenia Gourgari, Georgetown - Howard Universities

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 11 Concurrent Distinguished Pre-Doctoral and Post-Doctoral Oral Presentations (continued)

Saturday, April 21 | 9:00 AM – 10:00 AM

Roosevelt 4 Maryland A/B/C

First Year Medical Student Characteristics Associated A Multicenter Study of Fecal Microbiota with Readiness to Talk about Race Transplantation for Clostridium Difficile Infection in Brooke Cunningham, University of Minnesota CTSI Children Maribeth R. Nicholson, Vanderbilt University Medical Center Perspectives on Increasing Competency in Using Digital Practices and Approaches to Enhance Clinical TL1 Team Approach to Social and Genetic Translational Research: A Qualitative Study Determinants of Nocturnal Blood Pressure Katja Reuter, University of Southern California Leanne Dumeny, University of Florida Clinical and Translational Science Institute InCHOIR Learning Lab: a TL1 and Workforce Development Initiative at Mount Sinai Evaluation of the Current Status of Urologic Training Emma K.T. Benn, Icahn School of Medicine at Mount Sinai Programs in the Delivery of Transgender Care Daniel Schoenfeld, Albert Einstein College of Medicine Graduate Student Training Takes A New Format: “Avoiding The Kiss of Death” Investigation of Post-Operative Serum Creatinine Tracey Baas, University of Rochester Medical Center Trajectories Using Latent Class Mixed Modeling: A Novel Approach to Assessing Post-Cardiac Surgery Acute Kidney Injury Benjamin Andrew, Duke University

How have Characteristics of End-of-Life Family Care Giving Changed from 1999 to 2015? Preliminary Results from Two Waves of Nationally Representative Data Judith Vick, Johns Hopkins University School of Medicine

Virginia A/B/C Roosevelt 1

Risk of Readmission After Discharge from A Cluster-Randomized Trial of Symptom-based versus Skilled Nursing Facilities Following Heart Failure TST-based Screening of Pediatric Household TB Hospitalization Contacts to Improve IPT Uptake Himali Weerahandi, NYU - H+H Clinical and Translational Nicole Salazar-Austin, Johns Hopkins University School of Science Institute Medicine

Shared Decision Making in Child Health: A Qualitative Targeting Pulsatile Load to Increase Exercise Capacity Study of Parents of Children with Medical Complexity and Quality of Life After TAVR for Severe Aortic Stenosis Jody Lin, School of Medicine Anupam Kumar, University of Pennsylvania School of Medicine

Early Findings from a Real-World RCT: Acceptance and Uterine Serous Carcinoma is Associated with a High Commitment Therapy (ACT) for Persistent Pain in an Risk of Venous Thromboembolism Regardless of Integrated Primary Care Setting Latency from Surgical Staging Kathryn E. Kanzler, University of Texas Health Science Center Gregory M. Gressel, Albert Einstein College of Medicine San Antonio The Impact of Past 10-year and Current Alcohol Impact of Primary Care Physician Gatekeeping on Consumption Patterns on Progression of Carotid Intima Medication Prescriptions for Atrial Fibrillation Media Thickness Among Persons Living with HIV Andrew Young Chang, Stanford University School of Medicine Natalie Chichetto, Vanderbilt University Medical Center

Risk Factors for Prescription Opioid Misuse After Big Data Approaches in Translational Science: Traumatic Injury in Adolescents The Influence of Psychiatric and Trauma History in Teresa Maria Bell, Indiana University School of Medicine Predicting Future Smoking During Pregnancy in a Cohort of Female Like-Sex Twin Pairs Alexandra Noel Houston-Ludlam, Washington University in St. Louis, Institute Of Clinical and Translational Sciences

12 TRANSLATIONAL SCIENCE 2018 Saturday, April 21 | 9:00 AM – 10:00 AM (continued)

Roosevelt 2 Roosevelt 4

Cardiac Injury Due to Streptococcus Pneumoniae Exploring Müller Cell-Cone Interactions in Human Invasion During Severe Pneumococcal Pneumonia in a Fovea Using 3-Dimensional Volume Electron Novel Non-Human Primate Model Microscopy (EM) Luis F. Reyes, University of Texas Health Science Center San Ramya Singireddy, University of Alabama at Birmingham Antonio Point-of-Care Liquid Biopsy for Precision Diagnostics in Atopic Dermatitis and Ethnicity: Defining Variations in Recurrent Non-Small Cell Lung Cancer Molecular Phenotypes Nicole Blumenfeld, Columbia University, Irving Institute for Riana Dutt Sanyal, Icahn School of Medicine at Mount Sinai Clinical Translational Research

Drug Screening and Hit Identification for Night Association Between Source Case Cavitation Blindness with Zebrafish on Chest Radiograph and QuantiFERON-TB Gold Logan Ganzen, Indiana University School of Medicine InTube Conversion Among Close Contacts of Active Tuberculosis Cases in Brazil Predictive Cytological Topography (PiCT): A Lauren A. Saag, Vanderbilt University Medical Center Radiopathomics Approach to Mapping Prostate Cancer Decreased Uric Acid Transport is Associated with Sean D. McGarry, Medical College of Wisconsin Improved Outcomes Following Severe Traumatic Brain Injury Collagen Type I and II Blend Hydrogels for Articular Solomon M. Adams, University of Pittsburgh Cartilage Tissue Engineering Claire Elizabeth Kilmer, Purdue University Personalized Models of Distal Airway Epithelial-Stromal Unit in COPD Seyed Babak Mahjour, Weill Cornell Medical College

Roosevelt 3 Roosevelt 5

Sodium-Glucose Transporter 2 is a Novel Diagnostic Epidemiology of Traumatic Esophageal Injury: An and Therapeutic Target for Early-Stage Lung Analysis of the National Trauma Data Bank Adenocarcinoma Alexander Xu, Tufts University Claudio Scafoglio, David Geffen School of Medicine at UCLA Developing a Conceptual Model of Healthcare Access Associations Between Inflammatory Markers and for Adolescent Latinas in the US South Negative Symptoms in Individuals with Schizophrenia: Mercedes Margarita Morales Aleman, University of Alabama Converging Evidence at Birmingham David Goldsmith, Emory University Barriers to Healthcare After the Affordable Care Act: Mechanisms of Acquired Resistance to Gilteritinib A Qualitative Study of Los Angeles Safety Net Patients’ Therapy in Relapsed and Refractory FLT3-Mutated Experiences with Insurance and Healthcare Acute Myeloid Leukemia Sonali Saluja, University of Southern California Christine McMahon, University of Pennsylvania School of Medicine Understanding the Health Effects of Binding and Tucking for Gender Affirmation Extracellular Matrix as a Novel Approach to Tonia Poteat, Johns Hopkins University School of Medicine Glioma Therapy Mark H. Murdock, University of Pittsburgh Relationship Between Preexisting Pain and Completion of a Community-Based Wellness Program Chantay Young, Vanderbilt University Medical Center

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 13 ADVANCE YOUR CAREER

Join thousands of your clinical and translational science colleagues who receive specialized networking and education updates all year long.

GO ONLINE AT WWW.ACTSCIENCE.ORG TO START YOUR MEMBERSHIP TODAY. Poster Abstracts

CR Forum Top Ten Research Achievement Awardees 12 Reproducibility of Electronic Health Record Research Data Requests 1 Gene Therapy Halts Progression of Cerebral ALD Ram Gouripeddi, Rishi Dekha, Thomas Reese, Bradley Martin, Florian Eichler Jeff Talbert, Bernie LaSalle, Julio C. Facelli, Diana Brixner, Ryan Massachusetts General Hospital Butcher The University of Utah School of Medicine 2 Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain 13 Development of an Instrument to Identify Factors Timothy McAlindon Influencing Point of Care Recruitment in Primary Care Tufts Medical Center Settings. A Pilot Study at University of Utah Health Teresa Taft, Charlene Weir, Heidi Kramer, Julio C. Facelli 3 Single-Dose Gene-Replacement Therapy for Spinal The University of Utah School of Medicine Muscular Atrophy Jerry Mendell 14 Exposure to Violence Correlated to Elevated Nationwide Children's Hospital Immunoglobulin E and Epstein Barr Virus levels in African American Young Adults. 4 ATTRACT trial concludes clot-busting drugs do not prevent Latifa Jackson, Maksim Shestov, Forough Saadatmand long-term blood clot complications for most patients Georgetown - Howard Universities Suresh Vedantham Washington University School of Medicine in St. Louis 15 Prediction of 90-Day Readmission among Kidney Transplant Recipients using Natural Language Processing 5 Long-Term Outcomes of Patent Foramen Ovale Closure or Michael Arenson, Xingyu Zhang, Joyce Kim, Geeta Karadkhele,

Medical Therapy after Stroke Julien Hogan, Yiran Zhang, Andrew B. Adams, Rachel E. Patzer David Thaler Emory University Tufts Medical Center Education/Mentoring/Professional and Career Development 6 Risk/Benefit Comparison of Mechanical and Biologic Valve Replacements 16 First Year Medical Student Characteristics Associated Andrew Goldstone with Readiness to Talk about Race University of Pennsylvania Brooke Cunningham, Rachel Hardeman, Samantha Carlson University of Minnesota CTSI 7 Anti-Zika Virus DNA Vaccine Pablo Tebas 18 Perspectives on Increasing Competency in Using Digital Perelman School of Medicine at the University of Pennsylvania Practices and Approaches to Enhance Clinical Translational Research: A Qualitative Study 8 The Human Knockout Project Katja Reuter, Kelsey Simpson, Namquyen Le, Ricky N. Danish Saleheen Bluthenthal, Cecilia Maria Patino Sutton Perelman School of Medicine at the University of Pennsylvania University of Southern California 9 New CAR T-cell therapy for relapsed leukemia patients 19 InCHOIR Learning Lab: a TL1 and Workforce Development Nirali N. Shah Initiative at Mount Sinai National Cancer Institute Emma K. T. Benn, Janice Lynn Gabrilove, Emilia Bagiella Icahn School of Medicine at Mount Sinai 10 Treatment and Prevention of HIV-1 Infection by Highly Potent Neutralizing Monoclonal Antibodies 20 Graduate Student Training Takes A New Format: Marina Caskey “Avoiding The Kiss of Death” The Rockefeller University Tracey Baas, Sarah Peyre University of Rochester Medical Center Distinguished Oral Abstracts 21 TL1 Team Approach to Social and Genetic Determinants

of Nocturnal Blood Pressure Biomedical Informatics/Health Informatics/Digital Leanne Dumeny, Chu Hsiao, Hsiao, University of Florida, Larisa Health/Social Media H. Cavallari, Connie J. Mulligan, Wayne T. McCormack University Of Florida Clinical and Translational Science Institute 11 A Patient-Friendly Research Participant Registry: The UT Southwestern Volunteer Research Participant Registry 22 Evaluation of the current status of urologic training Kathleen Wilkinson, Sarah Lynch, ME Blair Holbein, Robert Toto, programs in the delivery of transgender care Duwayne Willett, Teresa Bosler, Samantha Gates, Mereeja Daniel Schoenfeld, Beth Drzewiecki Varghese, Vaishnavi Kannan Albert Einstein College of Medicine UT Southwestern Medical Center

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 15 Poster Abstracts (continued)

Health Equity/Community Engagement 32 Investigation of post-operative serum creatinine trajectories using latent class mixed modeling: A novel 23 Developing a Conceptual Model of Healthcare Access for approach to assessing post-cardiac surgery acute kidney Adolescent Latinas in the US South injury Mercedes Margarita Morales Aleman, Gwendolyn Ferreti, Isabel Benjamin Andrew, Carl F. Pieper, Anne D. Cherry, Jane F. C. Scarinci Pendergast, Jamie R. Privratsky, Carrie B. Moore, Mark Stafford- University of Alabama at Birmingham Smith Duke University 24 Barriers to Healthcare After the Affordable Care Act – A Qualitative Study of Los Angeles Safety Net Patients’ 33 How have characteristics of end-of-life family caregiving Experiences with Insurance and Healthcare changed from 1999 to 2015? Preliminary results from two Sonali Saluja, Danny McCormick, Michael Cousineau, Janina waves of nationally representative data Morrison, Michael Hochman Judith Vick, Jennifer Wolff University of Southern California Johns Hopkins University School of Medicine

25 Understanding the Health Effects of Binding and Tucking 34 Use of forced air warming devices to induce fever-range for Gender Affirmation hyperthermia in critically ill septic patients Tonia Poteat, Mannat Malik, Erin Cooney Anne Meredith Drewry, Enyo A. Ablordeppey, Marin H. Kollef, Johns Hopkins University School of Medicine Richard S. Hotchkiss Washington University in St. Louis, Institute Of Clinical and 26 Relationship between Preexisting Pain and Completion of Translational Sciences a Community-Based Wellness Program Chantay Young, Sifang Zhao, Tash Weddle, Sarah Jones, Digna Clinical Epidemiology/Clinical Trial Velez-Edwards, Katherine Hartmann Vanderbilt University Medical Center 35 Screening for multidrug resistant gram-negative bacilli in critically ill burn patients predicts subsequent bacterial Science and Health Policy/Ethics/Health Impacts/Outcomes etiology of infection. Research Anne Monica Lachiewicz, Melissa B. Miller, Shannon S. Carson, Bruce A. Cairns, David van Duin 27 Risk of Readmission after discharge from Skilled Nursing University of North Carolina School of Medicine Facilities Following Heart Failure Hospitalization Himali Weerahandi, Li Li, Jeph Herrin, Kumar Dharmarajan, Lucy 36 Kidney Transplantation: A High Risk State for Prediabetes Kim, Joseph Ross, Simon Jones, Leora Horwitz and Diabetes NYU - H+H Clinical and Translational Science Institute Colleen L Jay, Francis Tinney, Milagros Samaniego University of Texas Health Science Center San Antonio 28 Shared decision making in child health: a qualitative study of parents of children with medical complexity 37 Rapidly resolving acute respiratory distress syndrome: a Jody Lin, Catherine Clark, Bonnie Halpern-Felsher, Lee M. secondary analysis of the ARDS Network randomized Sanders controlled trials Stanford University School of Medicine Edward J Schenck, Clara Oromendia, Lisa Torres, David Berlin, Augustine M K Choi, Ilias I Siempos 29 Early Findings from a Real-World RCT: Acceptance and Weill Cornell Medicine Commitment Therapy (ACT) for Persistent Pain in an Integrated Primary Care Setting 38 Low cholesterol efflux capacity and abnormal lipoprotein Kathryn E. Kanzler, Patricia Robinson, Mariana Munante, Donald particles in youth with type 1 diabetes. McGeary, Jennifer Potter, Eliot Lopez, Jim Mintz, Lisa Kilpela, Evgenia Gourgari, Umberto Campia, Martin Playford, Amit Dey, Willie Hale, Donald Dougherty, Dawn Velligan Fran Cogen, Stephanie Gubb-Weiser, Sameer Desale, Maureen University of Texas Health Science Center San Antonio Sampson, Michelle Magee, Allen Taylor, Kristina Rother, Alan Remaley, Nehal Mehta 30 Impact of Primary Care Physician Gatekeeping on Georgetown - Howard Universities Medication Prescriptions for Atrial Fibrillation Andrew Young Chang, Mariam Askari, Jun Fan, Paul A. 39 A Cluster-Randomized Trial of Symptom-based versus Heidenreich, P. Michael Ho, Kenneth W. Mahaffey, Alexander C. TST-based Screening of Pediatric Household TB Contacts to Perino, Mintu P. Turakhia Improve IPT Uptake Stanford University School of Medicine Nicole Salazar-Austin, Silvia Cohn, Grace L Barnes, Molefi Tladi, Katlego Matlhaoleng, Catarina Swanepoel, Zarina Motala, 31 Risk Factors for Prescription Opioid Misuse after Ebrahim Variava, Neil Martinson, Richard E Chaisson Traumatic Injury in Adolescents Johns Hopkins University School of Medicine Teresa Maria Bell, Christopher A Harle, Dennis P Watson, Aaron E Carroll 40 Targeting Pulsatile Load to Increase Exercise Capacity Indiana University School of Medicine and Quality of Life After TAVR for Severe Aortic Stenosis Anupam Kumar, Julio Chirinos University of Pennsylvania School of Medicine

16 TRANSLATIONAL SCIENCE 2018 41 Uterine serous carcinoma is associated with a high risk of 49 Regulation of retinal protein O-GlcNAcylation by venous thromboembolism regardless of latency from angiotensin-(1-7) and cAMP surgical staging Sadie Dierschke, Amy Arnold, Michael Dennis Gregory M Gressel, Lauren Turker, Shayan Dioun, Nicole S. Penn State Clinical and Translational Science Institute Nevadunsky Albert Einstein College of Medicine 50 Comparing metabolic labeling of human tumors at different anatomic sites 42 The impact of past 10-year and current alcohol Divya Bezwada, Ralph DeBerardinis, Elizabeth Maher, Kevin consumption patterns on progression of carotid intima Courtney media thickness among persons living with HIV University of Texas Southwestern Medical Center Dallas Natalie Chichetto, Michael Plankey, Alison Abraham, David Sheps, Nicole Ennis, Xinguang Chen, Kathleen Weber, Steve 51 Characterizing Specialized Pro-Resolving Lipid Mediators Shoptaw, Robert Kaplan, Wendy Post, Robert Cook and Synthesis Pathways in Veterans with Peripheral Artery Vanderbilt University Medical Center Disease Joel Ramirez, Greg James Zahner, Sukaynah A. Khetani, 43 Big data approaches in translational science: the Kimberly A. Spaulding, Nancy K. Hills, S. Marlene Grenon influence of psychiatric and trauma history in predicting University Of California, San Francisco smoking during pregnancy in a cohort of female like-sex twin pairs. 52 A novel multi-photon microscopy method for Alexandra Noel Houston-Ludlam, Julia D. Grant, Kathleen K. neuronavigation in deep brain stimulation surgery Bucholz, Pamela A. F. Madden, Andrew C. Heath Nicholas Matthew George, Arianna Gentile Polese, Greg Futia, Washington University in St. Louis, Institute Of Clinical and Baris Ozbay, Wendy Macklin, Emily Gibson, Aviva Abosch, Diego Translational Sciences Restrepo, Brian E. Moore University of Colorado at Denver 44 Epidemiology of traumatic esophageal injury, an analysis of the National Trauma Data Bank 53 Sexual Dimorphism in a Mouse Model of Syndromic Alexander Xu, Janis L Breeze, Jessica K. Paulus, Nikolay Bugaev Thoracic Aortic Aneurysm Tufts University Zheying Chen, Alan Daugherty, Mary Sheppard University of Kentucky Center for Clinical and Translational 45 A Multicenter Study of Fecal Microbiota Transplantation Science for Clostridium difficile Infection in Children Maribeth R Nicholson, Erin Alexander, Mark Bartlett, Penny 54 Augmenting Perception Through Direct Electrical Becker, Zev Davidovics, Elizabeth Elizabeth Knackstedt, Michael Stimulation of Adult Somatosensory Cortex Docktor, Michael Dole, Grace Felix, Jonathan Gisser, Suchitra Yohannes Ghenbot, Andrew Richardson, Xilin Liu, Han Hao, Sam Hourigan, Kyle Jensen, Jess Kaplan, Judith Kelsen, Melissa DeLuccia, Greg Boyek, Jan Van der Spiegel, Timothy Lucas Kennedy, Sahil Khanna, McKenzie Leier, Jeffery Lewis, Ashley University of Pennsylvania School of Medicine Lodarek, Sonia Michail, Pediatrics, Paul Mitchell, Maria Oliva Hemker, Tiffany Patton, Karen Que 55 MicroRNA-451: a potential key player in the development Vanderbilt University Medical Center ‐ of diabetic nephropathy in an insulin resistant mouse model Maurice B Fluitt, Lijun Li, Narayan Shivapurkar, Carolyn Basic/Translational Science/Team Science Ecelbarger Georgetown - Howard Universities 46 Mucoidal Pseudomonas aeruginosa infection is associated with regional inflammation in the cystic fibrosis 56 Cardiac Injury Due to Streptococcus pneumoniae Invasion lung During Severe Pneumococcal Pneumonia in a Novel Non- Sankalp Malhotra, Daniel J. Wozniak, Don Hayes Jr. Human Primate Model The Ohio State University Luis F Reyes, Cecilia A. Hinojosa, Nilam J. Soni, Julio Noda, Vicki T. Winter, Melissa A. de la Garza, Jacqueline J. Coalson, Luis 47 Identifying the Role and Immunobiological Mechanisms of Giavedoni, Antonio Anzueto, Carlos J. Orihuela, Marcos I. Fli-1 Mediated Pathogenicity in Graft-versus-Host Disease Restrepo Steven Schutt, Yongxia Wu, Anusara Daenthanasanmak, David University of Texas Health Science Center San Antonio Bastian, Carole Wilson, Lynn Schnapp, Xian Zhang, Xue-Zhong Yu, Hung Nguyen 57 Atopic dermatitis and ethnicity: defining variations in Medical University of South Carolina molecular phenotypes Riana Dutt Sanyal, Ana B. Pavel, Tom C. Chan, Xiuzhong Zheng, 48 Antibiotics, early-life microbiota, and susceptibility to Jacob Glickman, Emma Guttman-Yassky asthmatic disease Icahn School of Medicine at Mount Sinai Timothy C Borbet, Jackie Li, Megan Daniele, Timothy Maher, Martin Blaser 58 Drug Screening and Hit Identification for Night Blindness NYU - H+H Clinical and Translational Science Institute with Zebrafish Logan Ganzen, Yuk Fai Leung Indiana University School of Medicine

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 17 Poster Abstracts (continued)

59 Predictive Cytological Topography (PiCT): a 69 Decreased Uric Acid Transport is Associated with Radiopathomics Approach to Mapping Prostate Cancer Improved Outcomes Following Severe Traumatic Brain Injury Sean D. McGarry, Sarah L. Hurrell, Kenneth Ickzkowski, Anjishnu Solomon M Adams, Yvette P. Conley, David O. Okonkwo, Ava M. Banerjee, Kenneth Jacobsohn, William Hall, Mark Hohenwalter, Puccio, Patrick Kochanek, Robert S. B. Clark, Philip E. Empey Peter LaViolette, Amy Kaczmarowski, Tucker Keuter,Marja University of Pittsburgh Nevalainen, William See Medical College of Wisconsin 70 Personalized Models of Distal Airway Epithelial-Stromal Unit in COPD 60 Collagen Type I and II Blend Hydrogels for Articular Seyed Babak Mahjour, Kazunori Gomi, Busub Lee, Olivier Cartilage Tissue Engineering Elemento, Scott Randell, and Renat Shaykhiev Claire Elizabeth Kilmer, Nelda Vazquez-Portalatin, Alyssa Weill Cornell Medical College Panitch, Julie C. Liu

Purdue University Group A: Thursday, 6:30 PM – 8:00 PM and 61 Sodium-Glucose Transporter 2 is a novel diagnostic and Friday, 7:00 AM – 7:45 AM therapeutic target for early-stage lung adenocarcinoma Claudio Scafoglio, Gihad Abdelhady, Jie Liu, Jane Yanagawa, Dean Wallace, Jorge Barrio, Steven Dubinett, David Shackelford Biomedical Informatics/Health Informatics/Digital Health/Social Media David Geffen School of Medicine at UCLA

A71 A Prospective Trial of Mobile Technology for Patient 62 Associations Between Inflammatory Markers and Negative Education in Spine Clinic Symptoms in Individuals with Schizophrenia: Converging Rasheedat Zakare, Eric Sankey, Theresa Williamson, Tracy Evidence Cheng, Oren Gottfried David Goldsmith, Robert Cotes, Brian Miller, Michael Treadway, Duke University Elaine Walker, Andrew Miller, Robert O. Cotes, Brian J. Miller, Michael T. Treadway, Elaine F. Walker, Andrew H. Miller A72 Sensitivity to Infusion and Blood Draw Time Recording Emory University Errors in Pharmacokinetic Modeling Hannah Lynn Weeks, Matthew S. Shotwell 64 Mechanisms of Acquired Resistance to Gilteritinib Vanderbilt University Medical Center Therapy in Relapsed and Refractory FLT3-Mutated Acute Myeloid Leukemia A73 Developing Objective and Ecologically Valid Measures Christine McMahon, Jonathan Canaani, Bryan Rea, Rachel Lynn for Cognitive Treatment Trials in Schizophrenia Sargent, Jennifer J.D. Morrissette, David B. Lieberman, Toral Surti, Deepak D'Souza, John Krystal, Robert McNeil Jr., Christopher Watt, Gregory W. Schwartz, Robert B. Faryabi, Mohini Ranganathan Timothy T. Ferng, Neil P. Shah, Catherine C. Smith, Martin Yale School of Medicine

Carroll, Alexander E. Perl A74 Promoting discussion and collaborations between University of Pennsylvania School of Medicine quantitative researchers and clinical researchers Dongmei Li, Thomas Fogg, Timothy De Ver Dye 65 Extracellular matrix as a novel approach to glioma therapy University of Rochester Medical Center Mark H. Murdock, Jordan T. Chang, George S. Hussey, Nduka M.

Amankulor, Johnathan A. Engh, Stephen F. Badylak A75 Clinic cycle time predicts provider performance on CG- University of Pittsburgh CAHPS Physician Communication assessment Rasheedat Zakare, Tracy Cheng, Oren Gottfried 66 Exploring Mü ller cell-cone interactions in human fovea Duke University using 3-dimensional volume electron microscopy (EM) Ramya Singireddy, Kenneth R. Sloan, Jeff W. Lichtman, Christine A76 Feasibility and acceptability of the Patient Reported A. Curcio, Dennis M. Dacey Outcomes Measurement Information System (PROMIS) in an University of Alabama at Birmingham outpatient gynecologic oncology clinic Gregory M Gressel, Shayan M. Dioun, Michael Richley, Akiva P. 67 Point-of-care liquid biopsy for precision diagnostics in Novetsky recurrent non-small cell lung cancer Albert Einstein College of Medicine Nicole Blumenfeld, Rodrigo C. Chaves, Janice C. Chung, Giuseppe Modica, Marie Slava, Michael Luetoff, Samuel K. Sia A77 A penalized regression analysis of errors made by a Columbia University, Irving Institute for Clinical high-dimensional, nonlinear, black box ensemble model Samuel Weisenthal, Samir Farooq, Martin Zand 68 Association between source case cavitation on chest University of Rochester Medical Center radiograph and QuantiFERON-TB Gold In-Tube conversion among close contacts of active tuberculosis cases in Brazil. A78 Development of a phenotyping system for smell

Lauren A Saag, Marcelo Cordeiro-SantosAfranio Kritski, Bruno disorders Yupu Liang, Michele Wong, Siddhartha Mitra, Julien Wen Hsieh Andrade, Solange Cavalcante, Betina Durovni, Megan Turner, The Rockefeller University Marina Figueiredo, Valeria Rolla, Timothy Sterling Vanderbilt University Medical Center

18 TRANSLATIONAL SCIENCE 2018 A79 Validation Of ICD-10 Codes For Bleeding Among Education/Mentoring/Professional and Career Development Patients With An Indication For Antithrombotic Therapy Sultan Khan, Yeshika Sharma, Margaret A. Olsen, Roger Yusen, A89 The Clinical Research Operations Program: Educating Melinda Miller, Richard White, Oluseun Atolagbe, Brian Gage, Clinical Research Staff Rabia P Saeed, Hannah Lin Peg Tsao, Veronica Haight, Ashley Dunn, Lisa Jackson, Steven Washington University in St. Louis, Institute Of Clinical and Goodman Translational Sciences Stanford University School of Medicine

A80 Quantification of Estimated Energy Expenditure in Burn A90 Behavioral Clinical Trials: Considerations for Design and Patients Using a Graphical Calculator Conduct Using the New NIH Study Protocol Template Elizabeth Megan Kenny, Francesco M. Egro, Ernest C. Manders Susan Lynn Murphy, Nancy Yovetich, Melissa Riddle University of Pittsburgh University of Michigan School of Medicine

A81 Rapid Prediction of Hematocrit Following Blood Loss A91 Sowing the “CEED”s of a More Diverse Biomedical and Fluid Shifts Using a Nomogram Workforce Elizabeth Megan Kenny, Francesco M. Egro, Ernest C. Manders Colleen A. Mayowski, Kaleab Z. Abebe, Natalia E. Morone, Doris University of Pittsburgh Rubio, Wishwa N. Kapoor University of Pittsburgh A82 Developing an Informatics Framework to Conduct Translational Research of Complex Diseases A92 Novice and Experienced Research Coordinators' Danielle Groat, Ramkiran Gouripeddi, Yu Kuei Lin, Willard Dere, Perceptions of A Standardized Training Julio Facelli Linda S Behar-Horenstein, JoNell Potter, Stephanie Swords, The University of Utah School of Medicine Stephen Allen Sonstein, Alena Prikhidko, Robert Kolb University Of Florida Clinical and Translational Science Institute A83 myRESEARCHhome – Analytics and new innovations in the Duke researcher portal A93 How Can We Improve Nutrition Education for Rebecca Namenek Brouwer, Derek Jones, Rebbecca Moen, Iain Physicians-in-Training? Sanderson, Ebony Boulware Emily Johnston, Jeannette M. Beasley, Penny M. Kris-Etherton Duke University Penn State Clinical and Translational Science Institute

A84 Temporal Characterization of Clinical Trial Descriptions A94 The Rockefeller Clinical Scholars Program, Supported in Samir E. Abdelrahman, Ram Gouripeddi, Jianyin Shao, Ryan Part by a KL2 Award: Data from 2006 - 2017 Butcher, Janette Vasquez, Bernie Lasalle, Julio C Faceilli Barry S. Coller, Sarah Schlesinger, Michelle Romanick, Jonathan The University of Utah School of Medicine Tobin, Donna Brassil, Rhonda Kost, Roger Vaughan, Robert MacArthur A85 Adoption of mHealth among Latinos with Rockefeller University Cardiometabolic Risk Factors Sabianca Delva, Hae-Ra Han A95 Case-based Learning in Translational Biomedical Johns Hopkins University School of Medicine Research Education Alexandra Joelle Greenberg-Worisek, Katherine Campbell, Eric A86 Ecological continuous assessment of physical activity Klee, Nathan Staff, Lisa Schimmenti, Karen Weavers, Stephen and sleep, and ecological momentary assessment of blood Ekker, Anthony Windebank pressure, body weight, and pulse wave velocity in an urban Mayo Clinic black population Stephen P. Wright, Emma J. Pollner, X. James Li, Jason J. A96 Frequently Overlooked Challenges of Pragmatic Trials Umans, Teletia R. Taylor, Carla Williams, Veronica Clarke- Rodger S Kessler, Constance O. Van Eeghen Tasker, Kathryn Sandberg Arizona State University Georgetown - Howard Universities A97 Clinical and Translational Research (CTR) Platform for A87 Diabetes and Hypogonadism: A population health Undergraduate Health Sciences Programs (UHSP) at approach using data analytics University of Puerto Rico-Medical Sciences Campus (UPR- Shyamashree Sinha, Paresh Dandona, Sarah Mullin, Tanvi Shah, MSC) and Universidad Central del Caribe (UCC): Pipeline for Peter Elkin Students and Faculty University At Buffalo, State University Of Rubén García García, Margarita Irizarry-Ramírez, Efraín Flores- Rivera, Carlamarie Noboa, José Moscoso- Álvarez, María E. A88 A Bootstrap-enhanced Least Absolute Shrinkage and González-Méndez, Mildred I. Rivera Vázquez Selection Operator Approach for Developing a Clinically University of Puerto Rico-Medical Sciences Campus Interpretable Model to Predict Suicide Christian Tyler Shanklin, Colin George Walsh, Matthew Charles A98 Drug Formulation Strategies: A Vital but Nearly Invisible Lenert Component in Translational Education Vanderbilt University Medical Center Robert Bruce MacArthur, Roger Vaughan, Barry S. Coller The Rockefeller University

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 19 Poster Abstracts (continued)

A99 Training Cycle in Clinical and Translational Research A110 An Electronic Roadmap to Customized Human (CTR) for Undergraduate Health Sciences Programs (HSUP) Research Training Plans at University of Puerto Rico-Medical Sciences Campus (UPR- Jennifer Maas, Megan Hoffman, Janet Shanedling, Jason MSC) and Universidad Central del Caribe (UCC): Pathway for Kadrmas, Trung Ngo, Jacob Johnson Students and Faculty. University of Minnesota - CTSI Margarita Irizarry-Ramírez, Rubén García García, Edgardo L. Rosado Santiago, José Moscoso- Álvarez, Elaine Ruiz Izcoa, A111 The leveling of clinical research competencies Carlamarie Noboa Carolynn Thomas Jones, Rebecca Namenek Brouwer, Carmen E. University of Puerto Rico-Medical Sciences Campus Aldinger, Robert Kolb, William Gluck, Barbara Bierer, Stephen Allen Sonstein A100 HiREC’s Endowment Sustain Capacity Building in The Ohio State University Promising Translational Researchers at a Minority Serving Institution: Four Successful Stories A112 The Boston Medical Center/Boston University Medical Aracelis Huertas Chardon, Lourdes E. Soto de Laurido Campus Research Professionals Network and its peer-led, University of Puerto Rico-Medical Sciences Campus competency-based workshop trainings Gina Daniels, MaryTara Roth A101 Building the Next Generation of Translational Boston University Researchers in Health Disparities Carlamarie Noboa, Zulmarie de Pedro-Serbía, Lourdes E. Soto A113 Research Development: Proactive Strategies to Foster de Laurido, Aracelis Huertas Chardon Faculty Success University of Puerto Rico-Medical Sciences Campus Elizabeth LaPensee, Jill Jividen, Tamara Havermahl University of Michigan School of Medicine A102 Critical and Creative Thinking Course: Fundamental for a Junior Researcher Health Equity/Community Engagement Lourdes E. Soto de Laurido, Marie K. Norman, Doris Rubio University of Puerto Rico-Medical Sciences Campus A115 Psychological Mechanisms Linking Food Insecurity and Obesity A103 Developing the Future Translational Science Workforce Candice Alicia Myers, Stephanie T. Broyles, Corby K. Martin, at the University of Iowa Peter T. Katzmarzyk James Torner, Beth Rydstrom Knudson, Kimberly Dukes Pennington Biomedical Research Center- LA CaTS University Of Iowa Institute for Clinical and Translational Science A116 Symptom Endorsement in Bipolar Patients of African vs A104 From Bedside to Benchmarks: A Physician-Scientist European Ancestry Workforce Dashboard for Biomedical Research Institutions Margaret Akinhanmi, Joyce E. Balls-Berry, Suliman El-Amin, Adrienne Zell, Lindsey Smith, David Yanez, Jeanne-Marie Guise, Jennifer Geske, Colin Colby, Christi Patten Joanna Biernacka, David Ellison Mark A. Frye Oregon Health & Science University Mayo Clinic

A105 Evaluation of a clinical investigation curriculum: Post- A117 Innovative Incorporation of a Community Engagement graduate outcomes Core in an Academic Medical Center Setting Julie H. Shakib, Carol Sweeney, Jodi Cullum, Ruben Rocha, Syed Mansoor Ahmed, Sarah P. O'Connor, Zeno Franco, David Anthea Letsou A. Nelson, Sharon Neu Young, Jessica De Santis The University of Utah School of Medicine Medical College of Wisconsin

A106 Perceptions of translational science among faculty A118 Multiplying Resources: Impact and Return On researchers: A survey to inform the efforts of a Investment of 10 years of Community-Engaged Research multidisciplinary education and research program (CEnR) and Partnership Seed Grants Gayathri Devi, Jennifer C. McMains, Stephanie A. Freel, Jeffrey Jen Brown, Melvin Thompson, Rebecca Carl, Maryann Mason, Hawley Gina Curry Duke University Northwestern University

A107 Assessing the impact of the KL2 mentored training A119 Developing a Cultural Adaptation of a Telephone program using the Becker model for research impact: An Genetic Counseling Intervention for Latina Women at-Risk of exploratory study Hereditary Breast and Ovarian Cancer Beatrice Boateng, Nia Indelicato, Pedro Delgado, Mary Aitken, Alejandra Hurtado de Mendoza, Sara Gómez Trillos, Marc Laura P. James Schwartz, Beth Peshkin, Heidi E. Hamilton, Katie Fiallos, Filipa C. University of Arkansas Translational Research Institute Lynce, Susan Vadaparampil, Vanessa B. Sheppard, Lucile Adams-Campbell, Andrea Otero, Kristi Graves A108 Immediate Feedback Through Mobile App Quizzing Georgetown - Howard Universities Becca Gas, Karen Marie Weavers, David Farley Mayo Clinic

A109 Utilizing Digital Pedagogy to Build Communication Skills in Predoctoral Training Programs Karen Marie Weavers, Becca Gas Mayo Clinic

20 TRANSLATIONAL SCIENCE 2018 A120 Community Based Research Networks: providing A128 Integrating Special Populations (ISP) in Research: infrastructure for clinical and translational research in the Examples from the University of Illinois at Chicago State of Michigan Raymond Allen Ruiz, Kevin Rak, Wendy Choure, Alicia Matthews, Meghan Spiroff, Patricia Piechowski, Karen D. Calhoun, Susan Amparo Castillo, Emily Anderson, Marilyn Willis Goold, Ayse Buyuktur, Michael Klinkman, Elias M. Samuels, University Of Illinois At Chicago Center for Clinical and Zachary Rowe Translational Science University of Michigan School of Medicine A129 The role of community in an evolving community- A121 Experiences, Challenges and Coping Strategies for university pilot award program Parents of Children with Autism in the United States and Sarah Wiehe, Gina Elizabeth Malloy Claxton, Lisa Staten, Elaine Different Arab Countries Lipscomb, Ann Alley, Eric Beers Mariam Ayyash, Marwa Ayyash, Mona Alaouie, Alexander Indiana University School of Medicine Blackwood University of Michigan School of Medicine A130 The Influence of Health Insurance Stability on Racial/Ethnic Differences in Diabetes Control and A122 Implementing and Evaluating an Evidence-based Management Intervention from the ICU Setting into Primary Care Using Alison G.M. Brown, Nancy R. Kressin, Norma Terrin, Amresh Promotoras to Reduce CA-MRSA Recurrence and Household Hanchate, Jillian Suzukida, Sucharita Kher, Lori Lyn Price, Amy Transmission LeClair, Elena Byhoff, Karen M. Freund Brianna M. D'Orazio, Jonathan N. Tobin, Rhonda G. Kost, Tufts University Chamanara Khalida, Jessica Ramachandran, Mina Pastagia, A131 Transforming an Academic Medical Center: Tracking Teresa H. Evering, Maria Pardos de la Gandara, Joel Correa da Community Engagement Rosa, Kimberly Vasquez, Getaw Worku Hassen, Franco Barsanti, Syed Mansoor Ahmed, Sharon Neu Young, Sarah P. O'Connor, Satoko Kanahara, Rosalee Nguyen, Mark Trezia, Trang Gisler, Mia DeFino, Zeno Franco, David A. Nelson Medical College of Alexander Tomasz, Barry S. Coller Wisconsin Clinical Directors Network (CDN) A132 Research Partnership, Community Commitment, and A123 Tool to Assess Opportunities to Augment Health the People-to-People for Puerto Rico (#p2p4PUR) Movement: Literacy & Culturally Responsive Components of Research Researchers and Citizens in Solidarity Design to Enhance Diverse Engagement Jose G Perez-Ramos, Hector Torres Zayas, Nancy R. Cardona Grisel Robles-Schrader, Ashley Sipocz, Evelyn Cordero, Gina Cordero, Dulce M. Del Rio Pineda, Colleen Murphy, Carmen M. Curry Velez Vega, Timothy De Ver Dye Northwestern University University of Rochester Medical Center

A124 Validation of a Set of "Healthcare Trust" Scales for A133 Barriers and facilitators to implementation of an HPV Women Seeking Substance Abuse Treatment in Community- vaccine program for girls in the Dominican Republic Based Settings Nancy VanDevanter, Erica Liebermann, Taraneh Shirazian, Joshua Cockroft, Deondria Matlock, Susie Adams Natalia Frías Gúzman, Mimi Niles, Danielle Ompad Vanderbilt University Medical Center NYU - H+H Clinical and Translational Science Institute

A125 Latent Classes of Polysubstance Use Among A134 Community Health Workers as Research Advocates Adolescents in the United States: Differences in Class Amparo Castillo, Emily Anderson, Alicia Matthews, Raymond Memberships by Sexual Identity Allen Ruiz, Wendy Choure, Kevin Rak, Marilyn Willis, Robert W.S. Coulter, Deanna Flynn, Jessica N. Fish, Michael W. University Of Illinois At Chicago Center for Clinical and Plankey Translational Science University of Pittsburgh A135 A Community-Academic Partnership to Understand the A126 Let’s talk about sex: Does language create a barrier to Correlates of Successful Aging in Place (Year 2) women reporting and receiving treatment for dyspareunia in Kimberly Vasquez, Dozene Guishard, William Dionne, Alexandra the Spanish speaking community? Jurenko, Caroline Jiang, Cameron Coffran, Andrea Ronning, Natalie Eisenach, Kimberly Swan, Dani Zoorob Glenis George-Alexander, Cynthia Mofunanya, Onassis Castillo University of Kansas Frontiers Ceballo, Lisa Tsatsas, Barry S. Coller, Jonathan N. Tobin, Rhonda G. Kost A127 Community Voices First: A Multi-Method Approach to The Rockefeller University Shaping Institutional Response to Flint's Water Crisis Karen D. Calhoun, Kent Key, E. Yvonne Lewis, Jennifer Carerra, A136 Current efforts to increase adolescent human Joseph Hamm, Susan Woolford, E. Hill De Loney, Ella Greene- papillomavirus vaccination rates using school-based setting Moten, Arlene Sparks, Don Vereen, Patricia Piechowski-Whitney, in Starr County, Texas Kaneesha Wallace, Ismael Byers, Athena McKay, DeWaun Ana Marina Rodriguez, Kathleen Schmeler, Sapna Kaul, Yong- Robinson, Jess Holzer, Vanessa De Danzine, Adam Paberzs, Fang Kuo Meghan Spiroff, Erica Marsh Univeristy of Texas Medical Branch University of Michigan School of Medicine

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 21 Poster Abstracts (continued)

Science and Health Policy/Ethics/Health Impacts/Outcomes A147 Protocol for a systematic review of existing patient- Research reported outcomes instruments for glaucoma Amanda Kiely Bicket, Jimmy Le, Michelle Tarver, Malvina A137 The effect of psychiatric service dogs on an objective Eydelman, Tianjing Li measure of stress and arousal in military veterans with PTSD Johns Hopkins University School of Medicine Kerri E Rodriguez, Douglas A. Granger, Crystal I. Bryce, Marguerite O'Haire A148 Integrating Ethics Support as Culture Change in a Purdue University Translational Science Environment Bernadette McKinney, Emma Tumilty, Joseph Kotarba A138 Trends in Anogenital Warts Incidence: Potential Impact University Of Texas Medical Branch At Galveston of Human Papillomavirus Vaccination, TennCare 2006-2015 Jaimie Zhi Shing, Marie Griffin, Manideepthi Pemmaraju, Edward A149 Long-Acting Reversible Contraceptive Uptake in Mitchel, Pamela Hull Female Sex Workers and Single Mothers in Rwanda and Vanderbilt University Medical Center Zambia Jessica Li, Rachel Parker, Kristin Wall, Lisa Haddad, Susan Allen A139 The Effect of Service Dogs on Employment, Health- Emory University Related Work Productivity, and Activity Impairment in a Population of Military Veterans with PTSD A150 Developing clinical prediction models for 30-day Marguerite O'Haire, Kerri E Rodriguez, Shelley Macdermid readmission in the medically complex pediatric population Wadsworth, Louanne Davis Jana Cerullo Leary, Lori Lyn Price, Cassandra ER. Scott, David Purdue University Kent, John B. Wong, Karen M. Freund Tufts University A140 Perceived Susceptibility to Cervical Cancer among African American Women in the Mississippi Delta A151 Two State Comparison of Orthopedic Utilization Elena Gibson, Julia Gage, Philip E. Castle, Isabel C.Scarinci Following Medicaid Expansion University of Alabama at Birmingham Christopher J. Dy, Derek Brown, Hera Maryam, Matt Keller, Margaret Ann Olsen A141 Profile of Pediatric Potentially Avoidable Transfers Washington University in St. Louis, Institute Of Clinical and Jennifer Rosenthal, James Marcin, Monica Lieng, Patrick Translational Sciences Romano University of California, Davis A152 Spontaneous Bacterial Peritonitis Mortality among Hospitalized Patients in the United States A142 Survival after early kidney after liver transplant Po-Hung Chen, Berkeley Limketkai, Brian Kim, Tinsay Woreta compared with simultaneous liver-kidney transplant and liver Johns Hopkins University School of Medicine transplant alone: Evaluating the potential of the “safety net” Colleen L. Jay, Ken Washburn, Mark Stegall, Glenn Halff, Greg A153 Racial Disparities in Long-Term Outcomes in Kidney Abrahamian, Jacqueline Pugh, Francis Tinney Transplantation from Elderly Donors in United States University of Texas Health Science Center San Antonio Silvi Shah, Shah, Masaaki Yamada, Roman Jandarov University of Cincinnati A143 Investigation into the Huntington’s Disease Community’s Views on Preventive Drugs A154 Polypharmacy and patterns of prescription medication Marcus Parrish, Kevin Grimes, Andrea Hanson-Kahn use among cancer survivors Stanford University School of Medicine Caitlin Murphy, Hannah Fullington, Carlos Alvarez, Simon Craddock Lee, Andrea Betts, David Haggstrom, Ethan Halm A144 Factors Associated with Dual Use of VA and Civilian University of Texas Southwestern Medical Center Dallas Healthcare Among US. National Guard and Reserve Soldiers Bonnie M. Vest, Jessica A. Kulak, D. Lynn Homish, Gregory G. A155 Exploring the relationships between acculturation, Homish discrimination and function in older African immigrants: a University At Buffalo, State University Of New York dissertation study Manka Nkimbeng, Yvonne Commodore-Mensah, Sarah Szanton A145 Prenatal near roadway air pollution exposure and early Johns Hopkins University School of Medicine neurodevelopment in young Mexican-American children: Findings from the CHAMACOS prospective birth cohort A156 Charting the Publication and Citation Impact of the NIH study Clinical and Translational Science Awards (CTSA) Program William H. Coe, Jason Feinberg, Robert Grunier, Brenda from 2006 Through 2016 Eskenazi, Heather Volk Nicole Llewellyn, Dorothy Carter, Latrice Rollins, Eric Nehl Johns Hopkins University School of Medicine Emory University

A146 Improvements in Surgical Mortality: The Roles of A157 A Qualitative and Quantitative Summary of the Content Complications and Failure to Rescue of Publications Supported by the National CTSA Program Brian T. Fry, Jyothi Thumma, Justin Dimick from 2006-2017: Diversity, Scope, and Inter-disciplinarity University of Michigan School of Medicine Nicole Llewellyn, Dorothy Carter, Latrice Rollins, Eric Nehl Emory University

22 TRANSLATIONAL SCIENCE 2018 A158 Balancing Patient-Centeredness and Patient Safety in A168 Is Less More? Examining the Relationship between the Hospitals: The Case of Pain Care and Patient Satisfaction Food Assistance Generosity and Childhood Obesity Olena Mazurenko, Basia Andraka-Christou, Matthew Bair, Areeba Megan M. Reynolds, Melanie Beagley, Ashley M. Fox, Ming Wen, Kara, Christopher A. Harle Michael W. Varner, Ken R. Smith Indiana University School of Medicine The University of Utah School of Medicine

A159 The Association of Preoperative Functional Capacity A169 Creating a Reference Analytics Morphomics Population and Outcomes for Head and Neck Cancer Patients from Surgical Patient Cross-Sectional Imaging Undergoing Definitive Surgical Treatment Katherine He, Brian Derstine, Sven Holcombe, Nicholas Wang, Sampat Sindhar, Dorina Kallogjeri, Troy S. Wildes, Michael S. Stewart Wang Avidan, Jay Piccirillo University of Michigan School of Medicine Washington University in St. Louis, Institute Of Clinical and Translational Sciences A170 Functional Imaging Demonstrates that Immune Parameters Modulate the Radiosensitivity of Locally A160 A Multi-Stakeholder Analysis on Preparing Future Advanced Non-small Cell Lung Cancer Pediatricians to Improve the Mental Health of Children Aneesh Krishna Pirlamarla, Changcheng Zhu, Chandan Guha, Cori Meredith Green, John Walkup, William Trochim Nitin Ohri New York Presbyterian Hospital/Weill Cornell Medicine Albert Einstein College of Medicine

A161 Thrombotic Complications in Single Ventricle Clinical Epidemiology/Clinical Trial Reconstructions for Single Ventricle Physiology Congenital Heart Disease A171 Mixed Meal Effects of Neprilysin Inhibition Michael Hugh White, Kavita Patel, Lazaros Kochilas, Robert F. Jessica Rose Wilson, Daniel Rader, Raymond Townsend, Sidonio, Jr. Michael Rickels Emory University University of Pennsylvania School of Medicine

A162 Nutritional Outcomes in Pediatric Oncology Patients A172 Empirical-likelihood-based criteria for model selection Less than 3 Years of Age on longitudinal data with dropout missingness Daniel Runco, Ann Mertens, Karen Wasilewski-Masker Ming Wang, Chixiang Chen Emory University Penn State Clinical and Translational Science Institute

A163 An Application of the Payback Framework to Evaluate A173 Plasma microRNA markers of upper limb recovery the Outcomes of Pilot Projects Supported by the Georgia following human stroke Clinical and Translational Science Alliance from 2007-2014 Matthew A Edwardson, Xiaogang Zhong, Amrita Cheema, Latrice Rollins, Nicole Llewellyn, Eric Nehl, Astrid Sosa Alexander Dromerick Morehouse School of Medicine Georgetown - Howard Universities

A164 The association of gastrointestinal symptoms and A174 The clinical implications of a positive prostate cancer hypertension in persons living with HIV on HAART screen in patients undergoing a cardiac transplant evaluation Kierra Renee Butler, Faye Harrell, Wendy A. Henderson Vaibhav Kumar, Hanyin Wang, David DeNofrio, David Kent National Institutes of Health Tufts University

A165 A Community-Academic Translational Research and A175 Using Father-mediated Intervention to Increase Learning Collaborative to Evaluate the Associations Among Responsive Parental Behaviors and Child Communication in Biological, Social and Nutritional Status For Adolescent Children with Autism Spectrum Disorder: A Pilot Study Women and their Babies Using Electronic Health Records Michelle Flippin (EHR) Data University of Rhode Island Jonathan Tobin, Amanda Cheng, Caroline S. Jiang, Mireille McLean, Peter R. Holt, Dena Moftah, Rhonda G. Kost, Kimberly A176 Predicting Age-Related Macular Degeneration S. Vasquez, Daryl L. Wieland, Peter S. Bernstein, Siobhan Dolan, Diagnosis, Progression, Severity, and Identification of Mayer Sagy, Abbe Kirsch, Michael Zinaman, Elizabeth DuBois, Potential Therapies: A Machine Learning Approach Barry Kohn, William Pagano, Gilles Bergeron, Megan Bourassa, Emily Brown, Jacob D. Ball, Zhaoyi Chen, Alfred S. Lewin, Mattia Stephanie Morgan, Judd Anderman, Shwu Huoy Kwek, Julie Prosperi, John D. Ash Wilcox, Jan L. Breslow University Of Florida Clinical and Translational Science Institute The Rockefeller University A177 Effect of balanced crystalloids on renal outcomes A166 Chronic Pain in Older Survivors of Hematopoietic Cell among critically ill adults does not differ from 0.9% saline Transplantation (HCT) – a report from BMTSS-2 across baseline risk of renal outcomes. Naveed Qazi Farrukh, Lindsey Hageman, Jessica Wu, Saro Andrew C. McKown, Todd W. Rice, Matthew W. Semler Armenian, Emily Ness, Mukta Arora, Michelle Kung, Smita Bhatia, Vanderbilt University Medical Center Liton Francisco, Mariel Parman University of Alabama at Birmingham A178 Effect of sedation and neuromuscular blockade regimens on outcomes after cardiac arrest A167 Assessing Research Impact: It Takes a Team Teresa May, Richard Riker, Gilles Fraser, Sachin Argarwal, Ashley Dunn, Michelle B. Bass Duarte Christine, Niklas Nielsen, David Kent, David Seder Stanford University School of Medicine Tufts University

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 23 Poster Abstracts (continued)

A179 An Assessment of Inappropriate Antibiotic Use for A188 The SAM Robot: A Social Skills Intervention for Uncomplicated Urinary Tract Infections Children with Autism Spectrum Disorder Michael J. Durkin, Matthew Keller, Anne Butler, Jennie Kwon, Erik Jenna Lebersfeld, Caleb J. Brasher, Christian D. Clesi, Carl E. Durbberke, Margaret Olsen Stevens, Fred J. Biasini, Maria I. Hopkins Washington University in St. Louis, Institute Of Clinical and University of Alabama at Birmingham Translational Sciences A189 Intersection of stunting, animal co-habitation and the A180 Identifying and characterizing anemia in patients with gut microbiota hidradenitis suppurativa Henry Rogalin, Honorine Ward, Marieke Rosenbaum, Noel Yssra S. Soliman, Lauren Hoffman, Juan Lin, Lewis Tomalin, Solomons, Janet Forreste Mark Chaitowitz, Michelle Lowes, Steven R. Cohen Tufts University Albert Einstein College of Medicine A190 Development of a Statin Risk Communication Tool for A181 Identification of Herpes Simplex Virus (HSV) Shedding Use in Cancer Survivors: A Pilot In The Female Genital Tract Of Pregnant Women By The Nirupa Jaya Raghunathan, Nassim Anderson, Emily Tonorezos, Xpert HSV 1/2 Assay and Routine PCR Deborah Korenstein Milza Opper, Jennifer Potter, Mark Prichard, David Kimberlin Memorial Sloan Kettering Cancer Center University of Alabama at Birmingham A191 Effectiveness of oral cryotherapy for the prevention of A182 Tatum: A Web-Based Tool for Obtaining a Treatment high-dose melphalan-induced oral mucositis: A randomized Allocation in Randomized Controlled Clinical Trial with a clinical trial Built in Tracking System for the Management of the Juan Jose Toro, Francisca Gushiken, David J. Haile, Cesar O. Randomization Process Freytes Shokoufeh Khalatbari, James Maszatics, Mehil Gunal, University of Texas Health Science Center San Antonio Vijayasaradhi Danda, Kellen McClain, Dawn Brown University of Michigan School of Medicine A192 Feasibility of Maternal Holding during Therapeutic Hypothermia for Infants with Encephalopathy A183 Does The Implementation Of Pneumonia Prevention Alexa Kanwit Craig, Kyle Deerwester, Leah Fox, Julia Jacobs, Practices Reduce Risk Of Pneumonia Following Coronary Scott Evans Artery Bypass Grafting? Tufts University Raymond Strobel, Michael P. Thompson, Lourdes Cabrera, Steven D. Harrington, Min Zhang, Richard L. Prager, Donald S. A193 Scrambler Therapy: Potential New Treatment for Likosky Central Neuropathic Pain? University of Michigan School of Medicine Maureen A. Mealy, Sharon L. Kozachik, Lawrence Cook, Marie T. Nolan, Thomas J. Smith, Michael Levy A184 Percentage of viable tumor versus radiation treatment Johns Hopkins University School of Medicine effect in surgical specimens is not associated with outcomes in recurrent glioblastoma A195 Cognitive and Behavioral Side Effects in Patients Robert David Schwab, Stephen Bagley, Zev Binder, Robert Treated with Droxidopa for Neurogenic Orthostatic Lustig, Donald O’Rourke, Steven Brem, Arati S. Desai, MacLean Hypotension Nasrallah Katherine McDonell, Cyndya Shibao, Italo Biaggioni, David University of Pennsylvania School of Medicine Robertson, Daniel Claassen Vanderbilt University Medical Center A185 Susceptibility to Social Influence is Associated with Alcohol Self-Administration and Subjective Alcohol Effects A196 Characterizing physician trust and healthcare-based Alyssa Schneider, Bethany Stangl, Elgin R. Yalin, Jodi M. Gilman, discrimination among long-term HIV viral trajectory groups in Vijay Ramchandani Washington, DC National Institutes of Health Katherine Gisella Michel, Cuiwei Wang, Allison Doyle, Camille Robinson, Joanne Michelle F. Ocampo, Lakshmi Goparaju, Seble A186 Cumulative Lead Exposure as a Risk Factor for Kassaye Resistant-Hypertension Georgetown - Howard Universities Alexander Zheutlin, Howard Hu, Marc G. Weisskopf, David Sparrow, Pantel Vokonas, Sung Kyun Park A197 Influence of Alcohol Use Disorder and Comorbid University of Michigan School of Medicine Psychopathology on Discounting of Delayed Rewards Julia Swan, Joshua L. Gowin, Matthew E. Sloan, Reza Momenan, A187 BREATHE-Easy Trial: A Dietary Intervention to Modify Vijay A. Ramchandani Asthma Health National Institutes of Health Emily Pfeil Brigham, Corrine Hanson, Amy Schweitzer, Abigail Thaxton, Jennifer Wineke, Tricia LeVan, Bobbie Barron, Meredith A198 Sleep disturbances in mothers of children with atopic McCormack, Susan Oh dermatitis throughout childhood: a population-based Johns Hopkins University School of Medicine longitudinal birth cohort study Faustine D. Ramirez, Shelley Chen, Aric A. Prather, Michael D. Cabana, Mary-Margaret Chren, Katrina Abuabara University Of California, San Francisco

24 TRANSLATIONAL SCIENCE 2018 A199 Post-operative pain control and opioid usage patterns A209 Neurophysiological Substrates and Developmental among patients undergoing thyroidectomy and Sequelae of Sensory Differences in Infants at High Risk for parathyroidectomy Autism Spectrum Disorder Theresa Tharakan, Sydney Jiang, Judd Fastenberg, Thomas Ow, Tiffany G. Woynaroski, Cara Damiano, David Simon, Lisa Ibanez, Bradley Schiff, Richard Smith, Vikas Mehta Michael Murias, Mark Wallace, Wendy Stone, Carissa Cascio Albert Einstein College of Medicine Vanderbilt University Medical Center

A200 Risk and Resilience: Identifying Factors that Predict A210 Fecal bile acids, fecal short chain fatty acids and the PTSD Symptom Trajectory in Veterans intestinal microbiota in patients with irritable bowel Ashkan Ahmadian, Aoife O'Donovan, Thomas C. Neylan, Thomas syndrome (IBS) and control volunteers Metzler, Beth Cohen Andrea Shin, David Nelson, John Wo, Michael Camilleri, Toyia University Of California, San Francisco James-Stevenson, Robert Siwiec, Matthew Bohm, Anita Gupta Indiana University School of Medicine A201 The Effects of Gravidity and Parity on Risk of Cognitive Impairment and Amyloid Plaque Deposition A211 Determining Patterns of Activity and Functional Rebecca DiBiase, Aozhou Wu, David Knopman, Keenan Walker, Connectivity in Emotion Processing and Regulation Neural Thomas Mosley, Pamela L. Lutsey, Rebecca Gottesman Circuitry in Offspring at Risk for Bipolar Disorder Johns Hopkins University School of Medicine Heather Elise Acuff, Amelia Versace, Michele A. Bertocci, Mary L. Phillips A202 Serum albumin level as a predictor of hospitalization University of Pittsburgh and death in older adults: the Atherosclerosis Risk in Communities (ARIC) Study A212 Metformin Induces a pro-immunogenic cytokine Colleen Moran Shannon, Morgan Grams, Elizabeth Selvin response in patients with Head and Neck Squamous Cell Johns Hopkins University School of Medicine Carcinoma Trisha Wise-Draper, Benyamin Yaniv, Sarah Palackdharry, Vinita A203 Association of plasma angiogenesis biomarkers with Takiar, Nooshin Hashemi Sadrei acute kidney injury and mortality following cardiac surgery University of Cincinnati William Ruxi Zhang, Sherry G. Mansour, Dennis G. Moledina, Steven G. Coca, Yaqi Jia, Heather Thiessen-Philbrook, Amit X A213 A role for FGF21 in postprandial nutrient homeostasis Garg, Jay Koyner, Michael G. Shlipak, F. Perry Wilson, Chirag R. after Roux-en-Y gastric bypass surgery Parikh Lydia-Ann Harris, Samuel Klein University Of California, San Francisco Washington University in St. Louis, Institute of Clinical and Translational Sciences A204 Long-acting opioid selection and the risk of serious infections in patients with non-cancer pain A214 Effect of the Microbiota-Derived Uremic Toxin Indoxyl Andrew D. Wiese, Marie Griffin, C. Mike Stein, William Schaffner, Sulfate on FMO Expression and TMAO Formation: A Pilot Robert Greevy, Edward F. Mitchel Jr., Carlos Grijalva Study Vanderbilt University Medical Center Alexander John Prokopienko, Raman Venkataramanan, Anand A. Joshi, Thomas D. Nolin A205 Effect of Dietary Approaches to Stop Hypertension University of Pittsburgh (DASH) Diet on Hemodynamic Markers in Advanced Heart Failure Patients A215 TL1 team approach to investigating the motivational Elisabeth Lilian Pia Sattler, Sandra B. Dunbar, Arshed A. spectrum in Parkinson’s disease Quyyumi, Jonathan R. Murrow, Richard D. Lewis, Henry N. Robert Stephen Eisinger, Bonnie Scott, Dawn Bowers, Aysegul Young, Whitni McConnell Gunduz Emory University University Of Florida Clinical and Translational Science Institute

Basic/Translational Science/Team Science A216 Alterations in the adrenal androgen biome during normal and premature adrenarche A206 Age-Dependent Anti-seizure and Neuroprotective Effect Juilee Rege, Josephine Z. Kasa-Vubu, Adina F. Turcu, Antonio M. of Cannabidivarin in Neonatal Rats Lerario Megan Huizenga, Patrick Alexander Forcelli University of Michigan School of Medicine Georgetown - Howard Universities A217 Surveillance of Global Tick-borne Diseases (TBD) in A207 Derivation of ocular lens fibers from human pluripotent Ecological Context: Geographic Distribution, Novel stem cells (hPSCs), a model to study human lens Biodiagnostic Testing, and Preventive Strategies for the Deaf development Population Rebecca Bricker, Tiziano Barberi Lorne Farovitch, Tim Dye, Ben Miller, Brian Leydet University of Texas Health Science Center San Antonio University of Rochester Medical Center

A208 TL1 Team Approach to Osteosarcoma Cell Detection A218 Determining if intestinal commensal bacteria enhance Pablo Joaquin Dopico, Henrietta Fasanya, Dietmar W. Siemann, the frequency of reassortment of an enteric, segmented Hugh Fan virus, reovirus. University Of Florida Clinical and Translational Science Institute Matthew Lanahan, Andrea Erickson, Julie Pfeiffer University of Texas Southwestern Medical Center Dallas

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 25 Poster Abstracts (continued)

A219 Increased Prevalence of Fibro-proliferative Disorders in A229 Brain resuscitative oxygen strategies in pediatric Patients with Central Centrifugal Cicatricial Alopecia cardiac arrest Oluwayemisi A. Dina, Crystal Aguh Alexandra Marquez, Todd J. Kilbaugh Meharry Medical College University of Pennsylvania School of Medicine

A220 Chronic inflammation-induced depletion of caveolin-1 A230 CD8+ cytotoxic T cells directly injure axons in the in Type 2 Diabetes mediates the development of Alzheimer’s Theiler’s murine encephalomyelitis model of multiple disease sclerosis Jacqueline A. Bonds, Zhenlong Chen, Leon Tai, Marcelo Bonini, William Schmalstieg Jacob Haus, Richard D. Minshall, Orly Lazarov University of Minnesota CTSI University Of Illinois At Chicago Center for Clinical and Translational Science A231 A Single-cycle Adenovirus Vaccine against Ebola Virus Stephanie S. Anguiano-Zarate, William E. Matchett, Pramod A221 The contribution of commensal oral bacteria to Nehete, Jagannadha K. Sastry, Michael A. Barry periodontal health through the regulated expression of Mayo Clinic neutrophil chemotactic molecules in the murine junctional epithelium A232 Targeted Eccentric Motor Control to Improve Ana Marie Chang, Adeline Hajjar, Richard Darveau Locomotion after Incomplete Spinal Cord Injury University of Washington Kevin O'Brien, D. Michele Basso, James Schmiedeler Indiana University School of Medicine A222 15N-Leucine transport across the blood brain barrier is significantly impaired in the glutamine synthetase-inhibited A233 Visual-spatial impairments after right-hemisphere brain stroke - let’s not neglect what’s not neglect! Shaun Evan Gruenbaum, Roni Dhaher, Kevin Behar, Hitten Anna Greenwald, Katrina Ferrara, Barbara Landau, Elissa Zaveri, Mark Erfe, Tore Eid Newport, Dorothy Farrar Edwards, Alexander Dromerick Yale School of Medicine Georgetown - Howard Universities

A223 Preeclamptic placental stromal cells exhibit defective A234 A CTSA External Reviewer Exchange Consortium; re-decidualization and reduced suppression of sFlt1 description and lessons learned transcription in vitro Margaret Schneider, Tanya Mathew, Madeline Gibson, Christine Margaret Sahu, Deepak Venkataraman, Alicia Smith, Martina Zeller, Hardeep Ranu, Adam Davidson Pamela Dillon, Nia Badell, Neil Sidell, Augustine Rajakumar Indelicato, Aileen Dinkjian Emory University Institute for Clinical and Translational Science - University of California, Irvine A224 A differential mobility-mass spectrometry platform for biomarker discovery in chronic kidney disease A235 Neural Correlates of Face Processing in Autism Stefanie Wernisch, Subramaniam Pennathur Spectrum Disorder: A Quantitative Meta-analysis of Current University of Michigan School of Medicine Literature & Future Directions Carla J Ammons, Mary-Elizabeth Winslett, Rajesh K. Kana A225 Cellular and molecular mechanisms of heart failure: University of Alabama at Birmingham toward an understanding of the role of Phospholamban in the regulation of cardiac function in humans A236 Mechanisms of KCNT1 pathogenesis in early-onset Maria Giovanna Trivieri, Roger Hajjar, Francesca Stillitano, epilepsy Delaine Cheholski, Kenneth Fish, Kevin Costa, Evangelia Tracy S. Gertler, Alfred L. George Jr. Kranias, Irene Turnbull Northwestern University Icahn School of Medicine at Mount Sinai A237 Establishing resting state MRI and magnetic resonance A226 Tumor suppressor RARRES1 regulates cell survival by spectroscopy as biomarkers for traumatic brain injury modulating mitochondrial energetics Robert Boggs, Lora Katherine Talley Watts, Geoffrey Clarke Sara Maimouni, Mi-Hye Lee, You-Me Sung, Chokri Ouaari, University of Texas Health Science Center San Antonio Stephen Byers Georgetown - Howard Universities A238 The Direct Effect of Trimethylamine-N-Oxide (TMAO) on Cardiac Muscle Contractile Mechanics A227 Day-to-day Association between Alcohol Use and Carlee I. Oakley, David Sanborn, Nikita Rafie, Matt Hendrix, Physical Activity in University Students Michael Grillo, Julian Vallejo, Jason R. Stubbs, Tilitha Shawgo, Scott Graupensperger, Michael Blair Evans Emmanuel Daon, George Zorn III, Michael J. Wacker Penn State Clinical and Translational Science Institute University of Kansas Frontiers

A228 EZH2 Inhibition Prevents Dysregulation of Critical A239 Central Autonomic Network Dysfunction Implicated in Survival Genes and Potentiates Standard-of-Care-Mediated Alcohol-Related Intimate Partner Violence Cell Death in Ewing’s Sarcoma Brandi C. Fink Pankita Hemant Pandya, Barbara Bailey, Adily Elmi, Courtney University of New Mexico Clinical and Translational Science Hemenway, Anthony Sinn, Lang Li, Jamie Renbarger, Karen Center Pollok Indiana University School of Medicine

26 TRANSLATIONAL SCIENCE 2018 A240 Characterization of human islet heterogeneity: A A250 Targeting Isoform-Specific PI3 Kinase Signaling for blueprint for stem cell derived islet regeneration Treatment of Cutaneous T Cell Lymphoma Joshua Wesley Ohde, Mike Slama, Quinn Peterson Suravi Raychaudhuri, Chi-Heng Wu, Weiyun Ai Mayo Clinic University Of California, San Francisco

A241 Impacts of postnatal nest change on early development A251 Decoding / encoding somatosensation from the hand Antonia Patrice Francis, Anna Kuznetsova, Keith Martinez II, area of the human primary somatosensory (S1) cortex for a Maria Gloria Dominguez-Bello closed-loop motor / sensory brain-machine interface (BMI) NYU - H+H Clinical and Translational Science Institute Brian Lee, Richard Andersen, Helena Chui, William Mack University of Southern California A242 Trauma Related Acute Respiratory Distress Syndrome (ARDS) in India: Current Incidence and Management A252 Optimizing Voice Therapy with Precision Rehabilitation Strategies Maria Bane, Joseph C. Stemple Tessa Adžemović, Pauline Park University of Kentucky Center for Clinical and Translational University of Michigan School of Medicine Science

A243 Transcriptome-wide alternative splicing patterns in A253 Physiological Reactivity as a Biomarker of Anxiety and septic children with bacterial and viral respiratory infections Depressive Symptoms in Youth Diagnosed with Chronic Sydney Elizabeth Behrmann, Jeffery Shadley, Michael Quasney Gastrointestinal Disease University of Michigan School of Medicine Bonney Reed-Knight, Tanja Jovanovic, Rebecca Hinrichs Emory University A244 Remembering Complex Scenes: New Methods to Assess Contextual Memory in PTSD A254 Impact of Spoken Sentence Predictability on Cognitive Elizabeth Duval, Rachel A. John, Sonalee A. Joshi, James L. Spare Capacity in Elderly Adults with Hearing Loss Abelson, Israel Liberzon Cynthia R. Hunter, David B. Pisoni, Dakota Collins, Larry E. University of Michigan School of Medicine Humes Indiana University School of Medicine A245 Characterization of the Host Pericyte Role in Glioblastoma Angiogenesis A255 Neural correlates of externally versus internally guided Frank Attenello III, Yingxi Wu, Kathleen Tsung, William Mack, dance-based therapies for people with Parkinson's disease Thomas Chen, Berislav Zlokovic Amrit Kashyap, Madeleine Hackney, Venkatagiri Krishnamurthy, University of Southern California Lisa Krishnamurthy, Krish Sathian, Bruce Crosson, Steve Wolf, Daniel Corcos, Jonathan Drucker, Marian Evatt, Gopi Kaundinya, A246 Patient-derived xenografts isolated from local New Aaron Bozzorg, Ariel Hart Orleans patients as a translational model to screen for novel Emory University kinase pathways in triple negative breast cancer Margarite D. Matossian, Hope Burks, Annie Bowles, Rachel A256 Novel PGF2a synthesis pathway in epithelial ovarian Sabol, Van Hoang, Steven Elliott, Bruce Bunnell, Alex Alfortish, cancer Krzysztof Moroz, Arnold Zea, Adam Riker, Steven Jones, Ayse Muhan Hu, Ekta Tiwary, Rebecca Arend, Michael Miller Ucar Bilyeu, Fokhrul Hossain, Lucio Miele, Kristin Miller, Elizabeth University of Alabama at Birmingham Martin, Benjamen O'Donnell, Nicholas Pashos, Matthew Burow, Bridgette Collins-Burow A257 Macrophages Protect Skeletal Muscle from Trauma- Tulane University School of Medicine- LA CaTS Induced Heterotopic Ossification by Regulating Dystrophic Calcification A247 Treatment with activated mesenchymal stem cells Stephanie Moore-Lotridge, Breanne HY. Gibson, Joseph T. increases long-term functional recovery following ischemic Martin, Gregory D. Hawley, Thomas H. Arnold, Masanori Saito, stroke via reduction of microglia activation and induction of Jonathan G. Schoenecker oligodendrogenesis Vanderbilt University Medical Center Matthew K. Tobin, Amelia M. Bartholomew, Orly Lazarov University Of Illinois At Chicago Center for Clinical and A258 Identifying the Genetic Determinants of Human Brown Translational Science Adipose Tissue Tobias Becher, Paul Cohen, Andreas Wibmer, Daniel J. Kramer A248 LDLR-Related Protien 1 Increases Cytokine Sensitivity- The Rockefeller University Implications for Recovery after Brain Damage Sadiya Ahmad, Reed A259 A robust spatial normalization pipeline for individuals University of Texas Health Science Center San Antonio with focal cortical lesions Andrew DeMarco, Peter Turkeltaub A249 Modulation of autophagy in intestinal health and Georgetown - Howard Universities inflammation Eliseo Castillo A260 Deciphering fat distribution through functional University of New Mexico Clinical and Translational Science genomics Center Kalypso Karastergiou Icahn School of Medicine at Mount Sinai

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 27 Poster Abstracts (continued)

A261 Protein production as an early pharmacodynamics A271 Neurocognitive Function in Adolescents with biomarker for RNA-Targeting Therapies Hyperthyroidism Wade Kerner Self, Kathleen Schoch, James Bollinger, Tracy Stephanie L. Samuels, Kosha Ruparel, Jeffrey Valdez, Allison M. Cole, Holly Kordasieqicz, Randall Bateman, Timothy Miller Port, Ruben C. Gur, Andrew J. Bauer Washington University in St. Louis, Institute of Clinical and University of Pennsylvania School of Medicine Translational Sciences A272 The Nasopharyngeal Microbiome is Perturbed and A262 STAG2 as a Biomarker for Prediction of Recurrence in Associated with Increased Clinical Severity During Acute Papillary Non-Muscle Invasive Bladder Cancer Respiratory Viral Infection Alana Lelo, Brent T. Harris, Deborah L. Berry, Krysta Chaldekas, Darrell Dinwiddie, Ashlee K. Bradley, Jesse L. Denson, Joshua L. Anagha Kumar, David Solomon, Jeffry Simko, Pritish Kennedy, Walter N. Dehority, Kurt C. Schwalm, Stephen A. Bhattacharyya, Ciaran Mannion, Jung-Sik Kim, George Phillips, Young Todd Waldman University of New Mexico Clinical and Translational Science Georgetown - Howard Universities Center

A263 EGFR Activation Contributes to Immune Evasion in A273 Lost and Found – Detection of Brain Cardiolipins in HNSCC Plasma after Cardiac Arrest Sean Korpela, Trista Hinz, Raphael Nemenoff, Sana Karam, Andrew Michael Lamade, Tamil S. Anthonymuthu, Elizabeth Ayman Oweida, Lynn Heasley Megan Kenny, Hitesh Gidwani, Nicholas Krehel, Valerian Kagan, University of Colorado at Denver Cameron Dezfulian, Hülya Bayır, Andrew A. Amoscato University of Pittsburgh A264 Quantitative Pathology for Alpha-Synuclein, Tau, and Amyloid Beta in Alzheimer’s Disease and Lewy Body A274 Rapid coaxial probe electrochemical (CoPE) ablation Disorders device development using computer aided design (CAD) and David Coughlin, Andrew Williams, Mendy Liang, John 3D printing Trojanowski, Daniel Weintraub, Andrew Siderowf, Murray Elliot Stein, Nicholas Perkons, Joseph Wildenberg, Stephen Hunt, Grossman, David Irwin Gregory Nadolski, Terence Gade University of Pennsylvania School of Medicine University of Pennsylvania School of Medicine

A265 Lafora Disease Premature Termination Codons (PTCs) A275 Inducing anti-tumor immunity in colorectal cancer are Likely Candidates for Suppression by Aminoglycosides Jonathan B. Mitchem, Yue Guan, Mark Daniels, Emma Teixeiro Zoe Raine Simmons, Amanda Sherwood, Selena Li, Sylvie Washington University in St. Louis, Institute Of Clinical and Garneau-Tsodikova, Matthew Gentry Translational Sciences University of Kentucky Center for Clinical and Translational Science A276 Urinary Tract Infections in Children with Kidney Allografts: Risk Factors and Clinical Consequences A266 The Role of Interleukin-23 in Human Melanoma Annie Farrell, Larry Greenbaum, Traci Leong Aditi Jani, Sandeep Chaudhary, Zorica Janjetovic, Mohammad Emory University Asif Sherwani, Nabiha Yusuf, Andrzej Slominski, Mohammad Athar, Craig Elmets A277 Impact of marijuana on cognitive performance among University of Alabama at Birmingham HIV-seropositive Hispanic women Bexaida Diaz, Miriam Matos, Kalpana J. Kallianpur, Rosa A267 Quantitative Structural Knee Measurements Improve Rodriguez, Shilpa Buch, Valerie Wojna Classification of Accelerated Knee Osteoarthritis: Data from University of Puerto Rico-Medical Sciences Campus the Osteoarthritis Initiative Lori Lyn Price, Timothy. E McAlindon, Mamta Amin, Charles B. A278 Desorption electrospray mass spectrometric Eaton, Julie E. Davis, Bing Lu, Grace H. Lo, Michael E. DeBakey, determination of isocitrate dehydrogenase mutation status Jeffrey Duryea, Mary F. Barbe, Jeffrey B. Driban and tumor cell percentage in human glioma biopsies during Tufts Medical Center tumor resection Clint Miles Alfaro, Valentina Pirro, Michael Keating, Eyas Hattab, A268 Linking LSD1 to Inflammation-Induced EMT Aaron Cohen-Gadol, Robert Graham Cooks Sam Miller, Heather O'Hagan Indiana University School of Medicine Indiana University School of Medicine A279 Solid-State MRI as a nonradiative alternative to A269 CXCR4 is required for progression of T cell acute computed tomography for craniofacial imaging lymphoblastic leukemia Rosaline Zhang, Hyunyeol Lee, Xia Zhao, Hee Kwon Song, Felix Cynthia Chen Wehrli, Scott Bartlett NYU - H+H Clinical and Translational Science Institute University of Pennsylvania School of Medicine

A270 Rational Target Selection for Gene Therapy A280 Pharmacokinetics of Phosphatidylethanol 16:0/20:4 Applications Guided by Microhomology-Mediated End Homolog in Human Blood After Consumption of 0.4 and 0.8 Joining g/kg Alcohol in a Laboratory Clinical Study Hirotaka Ata, Thomas Ekstrom, Kyle Schaefbauer, Jarryd Marisa Lopez-Cruzan, Nathalie S. Hill-Kapturczak, Jesus J. Campbell, Tanya Schwab, Alvin Ma, Karl Clark, Stephen Ekker Sanchez, John D. Roache, Tara Wright, Donald Dougherty, Mayo Clinic Martin Javors University of Texas Health Science Center San Antonio

28 TRANSLATIONAL SCIENCE 2018 A281 Melanoma associated antigen A3 (MAGE-A3) influences A291 The microbial-derived short chain fatty acid butyrate cutaneous squamous cell carcinoma growth in vivo directly and differentially inhibits gut T helper cell subset Alexis Santana, Nazanin Roudiani, Diane Felsen, John Carucci activation and proliferation. NYU - H+H Clinical and Translational Science Institute Jon Kibbie, Stephanie Dillon, Moriah Castleman, Jay Liu, Martin McCarter, Cara Wilson A282 Disruption of a Short Open Reading Frame (sORF) In University of Colorado at Denver The mRNA 5' Leader Sequence (5’LS) of the Type 1 Angiotensin Receptor (AT1R) Increases Angiotensin II (Ang A292 Genital Microbiomes of Women with Recurrent II)-Induced AT1R Internalization and Signaling through the Bacterial Vaginosis and their Regular Male Sexual Partner Extracellular Signal-Regulated Kinases Christina Ann Muzny, William J. Van Der Pol, Elliot J. Lefkowitz, Parnika Kadam, Hong Ji, Amrita V. Pai, Junfeng Ma, Robert Arindam Ghosh, Mei Li, David Redden, Xiangqin Cui, Jane Speth, Susette Mueller, Kathryn Sandberg Schwebke Georgetown - Howard Universities University of Alabama at Birmingham

A283 Validation of the Individuated Grip Gauge Interface as a A293 Altered Taste Reward Prediction Error and Cortisol Force Modulating Tool in Subjects After Stroke Response in Adolescent Anorexia Nervosa Berkenesh Gebrekristos, Daniel Neumaier, Adelyn Tsu, Karunesh Marisa C. Deguzman, Megan Shott, Brogan Rossi, Guido Frank Ganguly University of Colorado at Denver University Of California, San Francisco A294 Suppression of Ferroptosis through 12/15- A284 Development of Novel Mitochondrial Metabolism Lipoxygenase Inhibition is Neuroprotective after Traumatic Inhibitors Brain Injury Jay Patel, Stephen Byers Elizabeth Megan Kenny, Tamil S. Anthonymuthu, Qin Yang, Georgetown - Howard Universities Hulya Bayir, Lee Ann New, C. Edward Dixon, Valerian E. Kagan, Emin Fidan A285 Role of the antioxidant enzyme catalase in respiratory University of Pittsburgh syncytial virus infection Maria Ansar, Jeffrey M. Chambliss, Naryana Komaravelli, A295 Investigating the Role of Semaphorin 7a in Hormone Teodora Ivanciuc, Antonella Casola, Roberto P. Garofalo Receptor Positive Breast Cancer Progression University of Texas Medical Branch Lyndsey Crump, Alan Elder, Sarah Elizabeth Tarullo, Paris Franz, A286 Associations of Transthoracic Echocardiographic Traci Lyons features with Cardioembolic Stroke among patients without University of Colorado at Denver Atrial Fibrillation Michelle C. Johansen, Nicole L. Williams, Rebecca F. Gottesman A296 Vitamin C for the Treatment of KRAS Mutant Pancreatic Johns Hopkins University School of Medicine Cancer Anita Gade, Jonathan Zippin A287 Hitting the Bullseye: Identifying targeted therapy for NYIT College of Osteopathic Medicine Hnrnpu-related epilepsy Sarah Anne Dugger, Verity Letts, Matthew Halvorsen, Wayne A297 Development and validation of a translational rat model Frankel of neonatal abstinence syndrome Columbia University, Irving Institute for Clinical Lisa Brents, Bryce A. Griffin, Caitlin Caperton, Lauren Russell, Christian Cabanlong, Catheryn Wilson, Kyle Urquhart, Brad A288 The Role of The Gut Microbiota in Dopaminergic Martins, Amy L. Patton, Alexander W. Alund, S. Michael Owens, Neuron Vulnerability William E. Fantegrossi, Jeffery H. Moran Dimitri Koutzoumis, Jose Pino, Macarena Vergara, Julia University of Arkansas Translational Research Institute Buddendorf, Gonzalo Torres University Of Florida Clinical and Translational Science Institute A298 The influence of affect on behavior: Using computational modeling to improve the identification of A289 Variable off-target effects of clinically advanced PARP clinically-relevant social deficits inhibitors Katherine O'Connell, Brandon Padgett, Abigail A. Marsh Monicka Wielgos-Bonvallet, Jay Patibandla, Michelle Firlit, Georgetown - Howard Universities Paulina Cybulska, Elke Van Oudenhove, Petar Jelinic, Douglas A. Levine A299 The plasma contact system and its role in common NYU - H+H Clinical and Translational Science Institute variable immunodeficiency (CVID): an explorative study. Tukisa Smith, Manish Ponda, Jan Breslow, Charlotte A290 Specialized taster cells in sinonasal mucosa trigger IL- Cunningham-Rundles 25 mediated inflammation in chronic rhinosinusitis with The Rockefeller University nasal polyps Neil Nitin Patel, Michael A. Kohanski, Li-Yin Hung, James N. A300 Optogenetic stimulation of corticotropin-releasing Palmer, Nithin D. Adappa, De'Broski R. Herbert, Noam A. Cohen hormone expressing neurons in Barrington’s nucleus University of Pennsylvania School of Medicine recapitulates the social stress voiding phenotype in mice Jason Van Batavia, Stephan Butler, Joanna Fesi, Rita Valentino, Stephen Zderic University of Pennsylvania School of Medicine

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 29 Poster Abstracts (continued)

A301 Discriminating formal representations of risk in anterior B73 Analysis of the Initiation of Comfort Care Immediately cingulate cortex and inferior frontal gyrus Following Emergent Neurosurgical Operations John Purcell, Rena Fukunaga, William Hetrick, Joshua Brown Joseph R. Linzey, James F. Burke, Craig Williamson, Luis Indiana University School of Medicine Savastano, B. Gregory Thompson, Karin M. Muraszko, Aditya S. Pandey A302 Community Forums as a Channel for Communicating University of Michigan School of Medicine with the Public and to Influence Perceptions of Cancer Clinical Trials B74 Improved Quality of Care & Quality of Life for IBD Elizabeth Flood-Grady, Vaughan James, Janice L. Krieger Patients Using Mobile Based Remote Monitoring Platform: A University Of Florida Clinical and Translational Science Institute Randomized Control Trial

Ashish Atreja, Emamuzo Otobo, Benjamin Cohen, Laurie Keefer, A303 Guidance of surgical decision making by virtual cortical resection in medically intractable epilepsy Jason Rogers, Thomas Ullman, Steven Itzkowitz, Bruce Sands Fadi Mikhail, Lohith Kini, Kathryn Davis, Danielle Bassett, Brian Icahn School of Medicine at Mount Sinai Litt University of Pennsylvania School of Medicine B75 Use of Electronic Patient Reported Outcomes and Automated Devices for Heart Failure Disease Management A304 Tumor suppressors p53 and ARF control oncogenic Ashish Atreja, Emamuzo Otobo, Robert Freeman, Jennifer potential of triple-negative breast cancer cells by regulating Ullman, Marni Goldstein, Sean Pinney RNA editing enzyme ADAR1 Icahn School of Medicine at Mount Sinai Che-Pei Kung, Emily A. Bross, Catherine E. Kuzmicki, Michael Benjamin, Leonard B. Maggi Jr, Jason D. Weber B76 Mobile Enhancement of Motivation in Schizophrenia: Washington University in St. Louis, Institute Of Clinical and Improving Motivation with Text-Messages Translational Sciences Lauren Luther, Melanie A. Watkins, Annalee V. Johnson- Kwochka, Michelle P. Salyers A305 Feasibility, Acceptability, and Appropriateness of the Indiana University School of Medicine Menstrual Cup forShort Term Non-Surgical Management of Vesicovaginal Fistula (VVF) amongPotential Users and B77 Targeting Social Impairment in Serious Mental Illness Stakeholders Using Real-World Audio Recordings Nessa E. Ryan Kyle S. Minor, Paul H. Lysaker, Sarah E. Wiehe, Beshaun J. NYU - H+H Clinical and Translational Science Institute Davis, Matthew P. Marggraf, Megan L. Robbins

Indiana University School of Medicine A306 Authors’ Perceptions of the Interdisciplinarity of their Research B78 Natural Language Processing, and Machine Learning to Christine M. Weston, Mia S. Terkowitz, Daniel E. Ford

Johns Hopkins University School of Medicine Understand Successful Psychotherapy Adam Miner, Stewart Agras, Bruce Arnow, Nigam Shah, Steve A307 MYC-driven lymphomas suppress NK surveillance by Asch, Tim Althoff blocking maturation of early NK cells Stanford University School of Medicine Line Dam Heftdal, Srividya Swaminathan, Dean Felsher Stanford University School of Medicine B79 Augmented reality with Microsoft HoloLens as a training platform for healthcare professionals A308 Differential effects on hair and skin pigmentation Ian Anthony DeAndrea-Lazarus, Cabiria Monica Barbosu, following application of a topical soluble adenylyl cyclase Beatrice Aladin, Cheryl Smith, Jack Chang, Timothy De Ver Dye inhibitor University of Rochester Medical Center Olivia Wind, Dalee Zhou, Amanda Zippin, Jonathan Zippin Albert Einstein College of Medicine B80 Identifying Biologically Implausible Anthropometric Values in a Multisite Extraction of EHR Data for Secondary Use

Group B: Friday, 2:15 PM – 3:15 PM and 6:00 Dena S. Moftah, Daryl L. Wieland, Caroline S. Jiang, Amanda Cheng, Peter R. Holt, Jan L. Breslow, Michael J. Zinaman,

PM – 7:30 PM Jonathan N. Tobin Clinical Directors Network, Inc. (CDN) Biomedical Informatics/Health Informatics/Digital Health/Social Media B81 Choosing the best path: Determining data quality for B71 A Survey Assessment of Urologists’ Exposure to, subject identification within clinical research on Perception of, and Utilization of Focal Ablation for Primary buprenorphine use during pregnancy within a medical center Treatment of Prostate Cancer Brooke A. Levandowski, Lauren Miller, Ken Edell, Heather Link, Wilson Lin, Meenakshi Davuluri, Mark Schoenberg, Kara Watts Katelyn Carey, David Pinto Albert Einstein College of Medicine University of Rochester Medical Center

B72 Motor Adaptation to Sideway Tilted Gait Training in Children with Hemiparesis Yen-Sheng Lin, Tasos Karakostas, Yasin Dhaher Northwestern University

30 TRANSLATIONAL SCIENCE 2018 B82 Engaging Adolescents with Sexual Health Messaging: A B93 Fostering Cross-disciplinary Research: Lessons Learned Qualitative Analysis from STTEP-UP Lauren S. Chernick, Arianna Gonzalez, Suzanne Bakken, Melissa Hannibal Person, Adjoa R. Smalls-Mantey, Oluwasheyi Ayeni, Stockwell, Anke Ehrhardt, Carolyn Westhoff, John Santelli, Peter Dagmar Hernandez-Saurez, Emma K T Benn, Emilia Bagiella, Dayan Janice Lynn Gabrilove Columbia University, Irving Institute for Clinical Icahn School of Medicine at Mount Sinai

B84 Development and validation of a custom web-based B94 Teaching Rigor, Reproducibility, and Transparency interactive application for analysis of the renal resistive Using Gamification index as an acute kidney injury biomarker James Willig, Jennifer Croker, Brian Wallace, Donald Dempsey, Benjamin Andrew, Elias Y. Andrew, Anne D. Cherry, Mark David Redden Stafford-Smith University of Alabama at Birmingham Duke University B95 Listening for Empathy: Audio Narratives in DPT B85 Graphical Methods for Discovering Opioid Misuse Curriculum as a Model for Interprofessional Education Trajectories Jeffrey S. Farroni, Laura W. Farroni, Rebecca Russell Ram Gouripeddi, Linda Edelman, Peter Mo, Mollie Cummins UTMB Galveston The University of Utah School of Medicine B96 CTSI 500 Stars Initiative (CTSI of SE-Wisconsin) B86 Use of home-based telemedicine to improve healthcare Doriel D. Ward, Orsolya Garrison, Chamia Gary, Memory Bacon, utilization and outcomes in pediatric patients with poorly Tim Sobotka controlled type 1 diabetes The Medical College of Wisconsin Stephanie Crossen, Hadley Sauers-Ford, Shelby Chen, Victoria Tran, Breanne Harris, Nicole Glaser, James Marcin B97 Promoting Collaboration Among Researchers: A Team University of California, Davis Science Training Curriculum Jacqueline Knapke, Amy Short, Tamilyn Bakas, Jacinda Dariotis, B87 Toward Automatic Knowledge Discovery from Elizabeth Heubi, Saundra Regan, Barbara Speer, John Kues Biomedical Literature: A Case Study Using the National University of Cincinnati Health and Nutrition Examination Survey Diane Walker, Samir Abdelrahman, Julio C. Facelli B98 Acute Care Research Competencies for Clinical The University of Utah School of Medicine Research Professionals: A Practitioner Inquiry Approach and Assessment Education/Mentoring/Professional and Career Development Jacqueline Knapke, Brett Kissela, Lynn Babcock, Stephanie Schuckman B89 Development of toolkits to support for researchers University of Cincinnati integrating dissemination and implementation science into their translational research B99 Advancing research professionals through competency Rachel Tabak, Enola Proctor, Ana A. Baumann, Alexandra assessments Morshed Rebecca Namenek Brouwer, Denise C. Snyder, Deborah Washington University in St. Louis, Institute Of Clinical and Hannah, Christine Deeter Translational Sciences Duke University

B90 Expanding Our Educational Reach: Development of a B100 Research navigation services and onboarding: Massive Open Online Course (MOOC) Succeeding in the research environment Nicole L. O'Dell, Eric Fredericksen, Sarah Peyre Rebecca Namenek Brouwer, Geeta Swamy University of Rochester Medical Center Duke University

B91 Utilizing a reviewer database to facilitate integration of B101 Developing and Enhancing Mentoring Skills in Mid- an investigator-focused translational research and career Career Academic Faculty – An Update development program across the state of Indiana Keith Argenbright, Amy Mackenroth R. Lane Coffee, Jr., Julie Driscol, Tammy J. Saydyk, Anantha Moncrief Cancer Institute Shekhar, Scott C. Denne, Joe D. Hunt Indiana University School of Medicine B102 Selectives: Implementing self-directed collaborative selectives as part of a curriculum for pre-health care B92 A Qualitative Survey Study of Burn Units in the United professional students. States: Management of Burn Care and Pathways to a Career Leonor Corsino, Stephanie A. Freel, Melanie Bonner, Joan in Burn Surgery Wilson, Christie McCray, Maureen Cullins, Linda S. Lee, Kathryn Elizabeth Megan Kenny, Francesco M. Egro, Erica Johnson, M. Andolsek, Denise C. Snyder Aaron M. Foglio, Alain A. Corcos, Jenny A. Ziembicki Duke University University of Pittsburgh

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 31 Poster Abstracts (continued)

B103 Integration of Leadership Training for Graduate and B112 Evaluating the impact of a K-award on clinical and Medical Students Engaged in Translational Biomedical translational research Research: Examining Self-Efficacy and Self Insight Elias M. Samuels, Thomas E. Perorazio, Ellen Champagne, Celia Chao, Mark R. Hellmich, Kevin Wooten, Judy Aronson, Brenda Eakin Jonathan D. Hommel, Ross Ungerleider, Jamie Ungerleider University of Michigan School of Medicine UTMB B113 Evaluating the impact of a K-award writing seminar on B104 The need for an evidence-based CTS specific IDP for participants’ training grant awards. Early Career Training and for a Long-term and Sustainable Elias M. Samuels, Thomas E. Perorazio, Ellen Champagne, Career in Clinical Translational Sciences. Christine Byks-Jazayeri, Santinio Jones Camille Anne Martina, Janice Lynn Gabrilove, Naomi Luban, University of Michigan School of Medicine Cecilia Maria, Patino Sutton University of Rochester Medical Center Health Equity/Community Engagement

B105 Cure Quest: Teaching the complexities of drug B114 Chicago Kids Advisory Board: A novel approach to discovery and development through an adventure game engaging adolescent students in pediatric clinical research Benjamin Chang, Shawn Lawson, Kathleen Ruiz, Mei Si, Jeremy Ferdynand Hebal, Susanna McColley Stewart, Emilia Bagiella, Janice Lynn Gabrilove, Emma K. T. University of Chicago Benn RPI, School of Humanities, Arts and Social Sciences B115 The Value of Storytelling in Community Stakeholder Feedback for Clinical and Translational Research B106 Learning to LEAD: Leadership Emerging in Academic Laurie Lovett Novak, Sheba George, Kenneth Wallston, Yolanda Departments Vaughn, Tiffany Israel, Yvonne Joosten, Neely Williams, Janice Lynn Gabrilove, Cara Della Ventura, Layla Fattah, Consuelo Wilkins, Al Richmond Elizabeth Howell, Michele Fredericks, Lisa Bloom, Byron Cryer, Vanderbilt University Medical Center Helen Yin Icahn School of Medicine at Mount Sinai B116 Culture meets person-centered care: An empirical study of mental health and care planning among Latinx and B107 E-learning for Best Practices in Social and Behavioral Asian communities Research: A Multi-Site Pilot Evaluation Miraj U. Desai, Nadika Paranamana, Maria Restrepo-Toro, Luz Susan Lynn Murphy, Elias M. Samuels, Christine Byks-Jazayeri, Ocasio, Yolanda Herring, Merarilisse Crespo, Larry Davidson Ellen Champagne, Jordan Hahn, Brenda Eakin, Robert Kolb, Yale School of Medicine Linda S. Behar-Horenstein, Susan Gardner, Fanny Ennever, Mary-Tara Roth, Margarita L. Dubocovich, Gregory Homish, B118 Community-Informed Adaptation of Group Well Child

Meher Singh Visits for Limited English Proficiency Latino Families University of Michigan School of Medicine Rheanna Platt, Sarah Polk Johns Hopkins University School of Medicine B108 Mount Sinai Health Hackathon: harnessing the power of B119 collaboration to advance experiential team science education Environmental barriers and facilitators of health care Janice Lynn Gabrilove, Peter Backeris, Louise Lammers, Anthony access and utilization for elderly stroke survivors Costa, Layla Fattah, Caroline Eden, Jason Rogers, Kevin Costa Allison Brenner, Lesli E. Skolarus, Philippa J. Clarke, James F. Icahn School of Medicine at Mount Sinai Burke University of Michigan School of Medicine B109 Developing Personalized Pathways for Training using CTSA Core Competencies B120 Engaging, Capturing, and Integrating the Voice of the Susan Pusek, Beth Rydstrom Knudson, Rebecca Jackson, Joel Customer and Collaborator in a Clinical and Translational Tsevat, David H. Ingbar, Joan Davis Nagel Science Program University of North Carolina School of Medicine Boris Volkov, Jennifer Cieslak, Brook Matthiesen University of Minnesota CTSI B110 Phase II Award: Evaluation Of Outcomes In Preparing Independent Researchers By Continued Mentoring And B121 Efficacy of a 4-Part Program on Brain Development Career Development Support (2006-2016) Emily Silver, Nancy Michael Maria T. San Martin, Ruth Rios, Barbara Segarra, Karen G. Indiana University School of Medicine Martinez, Estela Estape, Margarita Irizarry-Ramírez University of Puerto Rico-Medical Sciences Campus B122 Childhood Adversity, Attachment Style, and Home Visiting Engagement B111 Implementing A Culture Changing Mentor Recognition Kelly M. Bower, Deborah Gross, Phyllis Sharps in Clinical and Translation Research Johns Hopkins University School of Medicine Christine Byks-Jazayeri, Elias M. Samuels, Elizabeth W. Anderson, Vickie Ellingrod University of Michigan School of Medicine

32 TRANSLATIONAL SCIENCE 2018 B123 Community Perspectives on Engagement in Clinical B133 Parental Perspectives on Factors Affecting Research Design, Conduct, and Dissemination Participation in Family Centered Rounds: Impact of Jen Brown, Cathy Samatas, Ashley Sipocz, Sarah Gabriella Technology Use in Trainee Presentations Hernandez, Maryann Mason, Gina Curry, Yaa Simpson, Paris Alexander Glick, Gabrielle Gold-von Simson, Michael Goonan, Davis Diana Sandmeyer Northwestern University NYU - H+H Clinical and Translational Science Institute

B124 Achieving Health Equity through Health Department- B134 Mixed Emotions: Health Care Personnel’s Reactions to Academic-Community Partnerships & Community-Engaged New Accountabilities for Health Equity Public Health Research: Healthy Chicago 2.0 Brooke Cunningham, Windy Fredkove, Alden Lai, Dimpho Jen Brown, Rachelle Paul-Brutus, Marc Atkins, Sarah Rittner, Orionzi, Jill Marsteller Doriane Miller, Amparo Castillo University of Minnesota CTSI Northwestern University B135 Disparities in Care Among Patients Presenting to the B125 "Translation is a Team Sport”: Exploring Scientists’ Emergency Department for Nephrolithiasis Perceptions of a Clinical & Translational Science Institute as Daniel Schoenfeld, Larkin Mohn, Joshua Stern, Ilir Agalliu a Vehicle for Collaboration Albert Einstein College of Medicine Rachel Elisabeth Damiani, Samantha Paige, Elizabeth Flood- Grady, Vaughan James, Edward Neu, Janice Krieger B136 The impact of health literacy, self-efficacy, University Of Florida Clinical and Translational Science Institute acculturation and education on cervical cancer screening practices among Hispanic women in South Texas. B126 CE Brokers: Sharing best practices across the CTSA Bertha Eloisa Flores, Martha Martinez, M. Tobar, M. Goros, consortium Jonathan Gelfond, Lyda Arevao-Flechas, D. Para-Medina Patricia Piechowski, Yvonne Joosten, Robynn Zender, Dana University of Texas Health Science Center San Antonio Burshell, Jen Brown University of Michigan School of Medicine Science and Health Policy/Ethics/Health Impacts/Outcomes Research B127 Target Populations Online Toolkits: An Introduction to Diversity in Research Participation B137 Johns Hopkins School of Medicine ClinicalTrials.gov Kevin Rak, Alicia Matthews, Amparo Castillo, Emily Anderson, Program Challenges and Successes Raymond Allen Ruiz, Wendy Choure, Marilyn Willis Anthony Keyes, Nidhi M. Atri, Prince Samuel Nuamah University Of Illinois At Chicago Center for Clinical and Johns Hopkins University School of Medicine Translational Science B138 Outcomes after Radical Prostatectomy for Prostate B128 Hypertension, Overweight/Obesity, and Diabetes Cancer in High-Risk Racial Cohorts among Immigrants in the United States: An Analysis of the Wilson Lin, Ahmed Aboumohamed, Ilir Agalliu, Saman Moazami, 2010-2014 National Health Interview Survey Evan Kovac, Kara Watts Yvonne Commodore-Mensah, Lisa A. Cooper Albert Einstein College of Medicine Johns Hopkins University School of Medicine B139 Understanding Care Delivered to Patients with a B129 Views of African American Parent-Child Dyads on the Possible Concussion at an Urban Level 1 Trauma Center Immunization Neighborhood to Improve HPV Vaccination Chet Christopher Zalesky, David W. Wright, Sanam Patel, Rachel Rates Koval Patzer Jennifer Erves, Pamela C. Hull, Consuelo H. Wilkins Emory University Vanderbilt University Medical Center B140 Utilization of ClinicalTrials.gov Registry to Demonstrate B130 Determining the prevalence and associated multi-level the Extent of Dissemination Bias in Anesthesiology characteristics of undiagnosed diabetic retinopathy Singh Nair, Davis Johns, Ellise Delphin, Jonathan Leff Kristen Nwanyanwu, Marcella Nunez-Smith, Mayur Desai, Icahn School of Medicine at Mount Sinai Thomas Gardner Yale School of Medicine B141 Patient Navigation Training – Community-Engaged Workforce Development Nirmal Ahuja, Joanne Sullivan, Eugene Lengerich B131 Qualitative study of obesity risk perception, knowledge Penn State Clinical and Translational Science Institute and behavior among Hispanic taxi drivers in New York. Aijan Ukudeyeva, Leandro Rafael Ramirez, Angel Rivera-Castro, B142 The Association of Financial Toxicity with Quality of Mohammed Faiz, Maria Espejo, Balavenkatesh Kanna Life (QoL) in Geriatric Oncology Patients: An Interim NYC Health + Hospitals Analysis of 349 Patients from 68 Oncology Practice Sites in

the University of Rochester NCI Community Oncology B132 Enhancing Outcomes for Young Children with Behavior Research program (UR NCORP) network

Disorders: A Model for Coordinated Care Asad Arastu, Mostafa R Mohamed, Joseph T. Ciminelli, Lianlian Sufna Gheyara John, Teresa Kramer, Nicola Edge, Michael Lei, Huiwen Xu, Megan Wells, Supriya Mohile Cucciare, Nicholas Long University of Rochester Medical Center University of Arkansas Translational Research Institute

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 33 Poster Abstracts (continued)

B143 (In)Adequacy of Prophylactic Central Lymph Node B152 Cost Effectiveness Analysis of Operative vs. Antibiotic Dissection for Papillary Thyroid Cancer in the U.S.: An Management for Uncomplicated Appendicitis Analysis of 18,755 Patients Eric Stulberg, Alexander Zheutlin, Raymond Strobel, Katherine Keven Seung Yong Ji, Taofik Oyekunle, Julie A. Sosa, Sanziana He, Adelyn Beil A. Roman Northwestern University Duke University B153 Post-Traumatic Stress Symptoms in Caregivers of B144 A Mixed-Methods Evaluation to Improve Sustainability Pediatric Hydrocephalus Population of Community Health Coalition Partnerships, Activities, and Kathrin Zimmerman, Alexandra Cutillo, Laura Dreer, Anastasia Impact on County-level Health Arynchyna, Brandon G. Rocque Jennifer Mansfield, Donna Vandergraff, Krystal Lynch, Douglas University of Alabama at Birmingham Miller, Dennis Savaiano Indiana University School of Medicine B154 Evaluating Iron Overload in Pediatric Cancer Survivors Ashley C Eason, Ann Mertens, Karen Effinger B145 Socioeconomic deprivation and late-stage breast Emory University cancer diagnoses among vulnerable women in the US Susanne Schmidt, Danielle Gordon B155 Attitudes and Preferences for Return of Results from University of Texas Health Science Center San Antonio Next-Generation Sequencing Matthew Neu, Jaimie Richards, Sara J Knight B146 Patient-Reported Satisfaction and Quality of Life in University of Alabama at Birmingham Women Undergoing Breast Reconstruction After Mastectomy: A Comparison of English and Spanish B156 Evaluation of Peripheral Calcium Score as a Measure of Speaking Women Peripheral Arterial Disease Severity Amanda Rizzo, Katie E. Weichman Sujin Lee, Shipra Arya, Kanika Kalra Albert Einstein College of Medicine Emory University

B147 Assessing the Reliability and Content Validity of the B157 The Real-Time IRB: A Collaborative Innovation to Gay Men’s Life Experiences Scale (GMLES): The GOLD Decrease IRB Review Time Studies Emily Connors, Ryan Spellecy, Annmarie Eve, Reza Shaker, Kristen Dionne Krause David Clark NYU - H+H Clinical and Translational Science Institute Clinical and Translational Science Institute of Southeast WI

B148 Evolution of the Interdisciplinary Co-Citation Network B158 Creating a Nomenclature for Describing Implementation Supported by the Georgia Clinical and Translational Science Strategies Used by Practice Facilitators in a Large, Pragmatic Alliance Program from 2006 Through 2016 Clinical Trial Dorothy R Carter, Nicole Llewellyn, Eric Nehl, Latrice Rollins Allison Cole, Laura-Mae Baldwin, Judith Schaefer Heidi Berthoud, The University of Georgia Michael Parchman, Gina Keppel University of Washington B149 No difference in long-term need for revision, length of stay, or complication rates between CAD/CAM vs. traditional B159 Tailoring implementation strategies for CVD risk craniofacial reconstruction for non-syndromic calculator adoption in primary care practice: Working to craniosynostosis accelerate adoption of evidence-based practice Regina Cho, Joseph Lopez, Leila Musavi, Alexandra Macmillan, Laura-Mae Baldwin, Leah Tuzzio, Erika Holden, Jen Powell, Ricardo Bello, Muhammad Faateh, Beita Badiei, Melanie Major, Allison Cole, Michael Parchman Amir Dorafshar University of Washington Johns Hopkins University School of Medicine B160 Trends in the use and cost of buprenorphine for opioid B150 Mind the Gaps: The Contraceptive Experience of use disorder: 2003-2015 Pregnant Adolescents in Louisiana Andrew W Roberts, Brendan Saloner, Stacie B Dusetzina Sarah Amanda Dumas, Ronald Horswell University of Kansas Frontiers Louisiana State University Health Sciences Center B161 Perceptions of “Translation” and the Application of B151 Can stage predict recurrence in papillary thyroid Research Across Disciplines at the University of Michigan cancer? A comparison of the 7th and 8th editions of the Misty Gravelin, Meagan Ramsey, Kanchan Lota, George Mashour American Joint Commission on Cancer staging system University of Michigan School of Medicine Alan Zambeli-Ljepović, Nathalie Chereau, Taofik Oyekunle, Sanziana Roman, Fabrice Menegaux, Julie Ann Sosa B162 The Association between Pro-BNP Changes During Duke University Inpatient Treatment for Heart Failure and 30-day Mortality Achint Patel, William Southern Albert Einstein College of Medicine

34 TRANSLATIONAL SCIENCE 2018 B163 Primary Closure of Wide Fasciotomy and Surgical B174 Prophylactic broad–spectrum antibiotics for childhood Wounds Using Rubber Band-Assisted External Tissue malnutrition Expansion: A Simple, Safe, and Cost-Effective Technique Amy Elizabeth Langdon, Xiaoqing Sun, Sheila Isanaka, Gautam Elizabeth Megan Kenny, Francesco M. Egro, James M. Dantas Russavage, Alexander M. Spiess, Tahsin Oğuz Acartürk Washington University in St. Louis, Institute Of Clinical and University of Pittsburgh Translational Sciences

B164 Post-Discharge Opioid Prescriptions and Their B175 ECG and Echo Characteristics in Familial Partial Association with Healthcare Utilization in the Vanderbilt Lipodystrophy: the impact of Lamin A variants Inpatient Cohort Study Abdelwahab Jalal Eldin, Rasimcan Meral, Adam Neidert, Diana Justin Scott Liberman, Lauren R. Samuels, Kathryn Margaret Rus, Rita Hench, Hakan Oral, Elif A Oral Goggins, Sunil Kripalani, Christianne Roumie University of Michigan School of Medicine Vanderbilt University Medical Center B176 Do Patient Comorbidities Impact the Effectiveness of a B165 Variable Utilization of Cross-Sectional Imaging Prior to COPD Self-Management Program? Percutaneous Peripheral Vascular Interventions Emilia Galli Thurber, Hanan Aboumatar Nathan K Itoga, Kenneth Tran, Vivian Ho, Ventia Chandra, Johns Hopkins University School of Medicine Ronald L. Dalman, Edmund J. Harris, Jason T. Lee, Matthew W. Mell B177 "Large patient volume is associated with adverse Stanford University School of Medicine patient outcomes among those requiring maintenance renal replacement therapy" B166 Genomic disorders, chronic kidney disease and Scott Reule, Robert Foley, Areef Ishani, Mark Rosenberg neurocognitive status in children University of Minnesota CTSI Hilda Fernandez Columbia University, Irving Institute for Clinical B178 Prognostic Value of Left Ventricular Mitral Annular Longitudinal Displacement measured by Tissue Doppler B167 Improving ClinicalTrials.gov Compliance: A Imaging in patients with Acute Coronary Syndrome Coordinated Effort for Success Mats Lassen, Kristoffer Grundtvig Skaarup, Allan Zeeberg Scott Patton, Elaine Basaca, Jennifer Swanton Brown Iversen, Peter Godsk Jørgensen, Flemming Javier Olsen, Jan Stanford University School of Medicine Skov Jensen, Tor Biering-Sørensen University Of California, San Francisco B168 OHRP meets ToS: Cloud-based Technologies in Human Subject Research B179 Investigating the Association Between Type 2 Diabetes Assya Pascalev and Early Knee Cartilage Degeneration via Quantitative MRI – Georgetown - Howard Universities A Pilot Study on the Metabolic Subtype of Osteoarthritis Joe Darryl Baal, Sarah Foreman, Gabby Joseph, Thomas Link B169 Development of the Expanded Access Oversight University Of California, San Francisco Committee at Michigan Medicine Kevin Weatherwax, Ray Hutchinson, George Mashour, Misty B180 A Prediction Model for Thyroid Cancer with Integration Gravelin of Patient Demographics, History, Ultrasound Characteristics University of Michigan School of Medicine and Bethesda Classification Theresa Tharakan, Thomas Ow, Viswanathan Shankar, Bradley Clinical Epidemiology/Clinical Trial Schiff, Richard Smith, Vikas Mehta Albert Einstein College of Medicine B171 Comparison of MRI-Ultrasound Fusion Prostate Biopsy Outcomes in High-Risk Ethnic Cohorts at a Diverse Urban B181 Children with acute lymphoblastic leukemia have Academic Center increased arginase 2 at birth, implicating Wilson Lin, Abhishek Srivastava, Ethan Fram, Victoria Chernyak, immunosuppression in leukemogenesis Kara Watts Amalie Bach Nielsen, Mi Zhou, Adam de Smith, Lucie McCoy, Albert Einstein College of Medicine Helen Hansen, Paige Bracci, Scott Kogan, Catherine Metayer, Xiaomei Ma, Joseph Wiemels B172 Synthetic Cannabinoid Usage among Psychiatric University Of California, San Francisco Inpatients Claire Louise Mann, Anahita Bassir Nia, Sharron Spriggs, Steven B182 Addressing Challenges from missing data in a Global Carbonaro, Dan DeFrancisco, Yasmin Hurd Quality Improvement Study Icahn School of Medicine at Mount Sinai Amelia Barwise, Lisha Yi, Jun Guo, Ognjen Gajic, Moldovan Sabov, Yue Dong, Rahul Kashyap B173 Subjective, Physiological Activation and Habituation, Mayo Clinic and Response to Written Trauma Narrative Exposure Mary Katherine Howell, Jennifer R. Myers, Thomas A. Mellman Georgetown - Howard Universities

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 35 Poster Abstracts (continued)

B183 A Phase Ib study of AEB071, a PKC inhibitor, and B193 The Effect of Allopurinol on Pediatric Patients BYL719, a PI3Kα inhibitor, in Patients with Metastatic Uveal Undergoing Maintenance Chemotherapy for Acute Melanoma Lymphoblastic Leukemia or Lymphoblastic Lymphoma Kimberly M Komatsubara, Richard Carvajal Mariam Moazzem Bhuiyan, Gordon Cohen, Stacy Cooper Columbia University, Irving Institute for Clinical Johns Hopkins University School of Medicine

B184 Diagnostic Efficacy of Tracking Regional Brain B194 Delirium and Catatonia: Age Matters Volumetric Changes in Patients with Mild Cognitive Jo Ellen Wilson, Richard Carlson, Maria C. Duggan, Pratik Impairment using FDA Approved Automated Quantification Pandharipande, Timothy D. Girard, Li Wang, Jennifer L. Software Thompson, Rameela Chandrasekhar, Andrew Francis, Stephen Christopher Calixte, Ziwei Zhang, Jeffery Petrella E. Nicolson, Robert S. Dittus, Stephan Heckers, E. Wesley Ely Duke University School of Medicine Vanderbilt University Medical Center

B185 Cathodal Transcranial Direct Current Stimulation (tDCS) B195 Geographic Distribution of Skull Base Malignancies: in Mild Cognitive Impairment (MCI): A Randomized, Double- Using Spatial Epidemiology to Better Understand the Blind, Sham-Controlled Pilot Study Etiology Rare Cancers Stefanie Velgos, Paul E. Croarkin, Gregory A. Worrell, Yonas E. Jeffrey Lee Nadel, Erin McKean Geda University of Michigan School of Medicine Mayo Clinic B196 Urinary and sexual function after perineal B186 Examining Characteristics of Placebo Effects on urethrostomy: A multi-institution analysis from Trauma and Trauma- Related Insomnia in a Suvorexant Trial Urologic Reconstructive Network of Surgeons (TURNS) Kimberly Uweh Kirkpatrick Beekman Fergus, Thomas W. Gaither, Gregory P. Georgetown - Howard Universities Murphy, Nima Baradaran, Benjamin Breyer UCSF B187 Craving and Mood Symptoms in Patients Addicted to Alcohol B197 Pathway of Protection: Ethnic Identity, Self-Esteem, and Roshni Janakiraman, Vijay Ramchandani, Melanie Schwandt, Substance Use among Multiracial Youth Laura Kwako, Nancy Diazgranados Sycarah Fisher, Tamika Zapolski National Institutes of Health University of Kentucky Center for Clinical and Translational Science B188 Obstructive Sleep Apnea as an Independent Predictor of Postoperative Delirium and Pain: An Observational Study B198 Attitudes toward physical activity and nutrition of a Surgical Cohort intervention during treatment for breast cancer Patricia K. Strutz, Vanessa L. Kronzer, Mark D. Willingham, Anne Gilmore, Lucio Miele, Leanne M. Redman Amrita Aranake-Chrisinger, William S. Tzeng, Arbi Ben Abdallah, Pennington Biomedical Research Center- LA CaTS Simon Haroutounian, Michael S. Avidan Washington University in St. Louis, Institute Of Clinical and B199 A Collaborative Neurology-Emergency Medicine Rapid Translational Sciences Outpatient Clinic for the Management of TIA and Minor Stroke in the Emergency Department B189 The relationship between cognitive functioning and Bernard P. Chang, Rachel Mehendale, Eliza Miller, Benjamin abnormal eating behavior in behavioral variant Kummer, Joshua Willey, Mitchell Elkind frontotemporal dementia Columbia University, Irving Institute for Clinical Vidyulata Kamath, Grace-Anna Chaney, Chiadi Onyike Johns Hopkins University School of Medicine B200 Donor Age and Allograft Survival in Liver Transplant Recipients with Hepatitis C Virus in the Direct-Acting B190 A Prospective Study of Cancer Clinical Trial Availability Antiviral Era and Enrollment among Adolescents/Young Adults Treated at Allison Kwong, Nathan Kim, Ajitha Mannalithara, W. Ray Kim a Children’s Hospital or Affiliated Adult Cancer Specialty Stanford University School of Medicine Hospital Stefanie M. Thomas, Jemily Malvar, Henry Tran, Jared Shows, B201 Impact of Air Quality in the NICU on Preterm Infants' David R. Freyer Urinary Oxidative Stress Biomarkers University of Southern California Helena Juditha Villalobos, Grace E. McInerney, Emily A. Spear, Homero Harari, Hsaio-Hsein Leon Hsu, Annemarie Stroustrup B191 Depression, Anxiety, and Planning for the Future: Icahn School of Medicine at Mount Sinai Associations with Advance Care Planning Ryan McMahan, Evan Walker, Rebecca Sudore B202 Long-term response to treatment and disease University of California, San Francisco School of Medicine recurrence in a prospective cohort of morphea patients Stephanie Florez-Pollack, Jack C. O'Brien, Heidi T. Jacobe University of Texas Southwestern Medical Center

36 TRANSLATIONAL SCIENCE 2018 B203 Racial/ethnic variation in the relationship between B212 Relationship Power Imbalance and History of Male metabolic syndrome components and cardiovascular Partner HIV Testing Among Pregnant Women in Central disease and the role of uric acid among population with Uganda metabolic syndrome Caroline Vrana, Jeffrey Korte, Angela Malek, Esther Buregyeya, Magda Shaheen Joseph Matovu, Harriet Chemusto, William Musoke, Rhoda David Geffen School of Medicine at UCLA Wanyenze Medical University of South Carolina B204 National Dissemination of the Accrual to Clinical Trials (ACT) Network across the Clinical and Translational Science B213 Targeting Immunosuppressive Myeloid Cells to Award (CTSA) Consortium Enhance Cancer Immunotherapy Elaine H. Morrato, Lindsay Lennox Xin Lu University of Colorado at Denver Indiana University School of Medicine

B205 Pembrolizumab for Patients with Leptomeningeal B214 The Role of Lysyl Oxidase in Systemic Sclerosis- Disease from Advanced Solid Tumors Associated Lung Fibrosis Jarushka Naidoo, Chen Hu, Karisa Schrek, Roisin Connolly, Xinh-Xinh Nguyen, Tetsuya Nishimoto, Takahisa Takihara, Logan Cesar Santa-Maria, Evan Lipson, Ranee Mehra, Chetan, Mlakar, Ellen Riemer, Jonathan Heywood, Amy Bradshaw, Carol Bettegowda, Kristin Redmond, Arun Venkatesan, Stuart Feghali-Bostwick Grossman Medical University of South Carolina Johns Hopkins University School of Medicine B215 Discovery and Evaluation of FOXP3 Dimerization Basic/Translational Science/Team Science Inhibitors Ravyn Thompson, Cara Coleman, Nathan G. Dolloff B206 Drug Development Core Facilitates Institutional Medical University of South Carolina Collaboration and Translational Science Innovation Gene Morse, Igor Puzanov, Andrei Gudkov, Robin DiFrancesco, B216 Surface Display of Chimeric Proteins for Exosome William Jusko, Marc Ernstoff, James Mohler, Timothy Murphy, Imaging and Capturing in Mammalians Robert Bies Mai Anh Do, Daniel H. Levy, Stacie Lim, Natalie Duong, Kevin University At Buffalo, State University Of New York Curley, Grace Ling, Biao Lu Santa Clara University B207 Formative Evaluation and Adaptation of a Safe Sleep Intervention for Infants in Rural Underserved Communities B217 Analysis of the Nature of Paclitaxel Resistance in APC Rosemary Nabaweesi, Mary Aitken, Keneshia Bryant-Moore, Knockdown Breast Cancer Cells Geoffrey M. Curran Jeni Prosperi, Bronwyn J. Berkeley, Emily Astarita, Anne Arnason University of Arkansas Translational Research Institute Indiana University School of Medicine

B208 Use it but still lose it: Exploring age-related changes in B218 Protective effects of estrogen against hypoxia skeletal stem cell location and activation in response to Ibolya Rutkai, Tyler C. Dean, Ashwin Adivi, Prasad V G Katakam, physical stimulation David W. Busija Pamela Cabahug Zuckerman, Chao Liu, Alesha B. Castillo Tulane University School of Medicine- LA CaTS NYU - H+H Clinical and Translational Science Institute B219 Single cell genomic profiling of human B cells that are B209 Multivariate Air Pollutant Exposure Prediction in South responsible for immune response against pneumococcal Carolina polysaccharides in aging HIV-negative and HIV-positive Ray Boaz, Andrew Lawson, John Pearce individuals Medical University of South Carolina Myroslawa (Myra) Happe, Devadoss Samuvel, Anita Iyer, Julie Westerink B210 Synaptic vesicle 2 receptors as a novel targets for Medical University of South Carolina neuroendocrine cancer therapy Renata Jaskula-Sztul, Jason D.Whitt, Jianfa Ou, Margaret X. Liu, B220 Effects of bilateral frontal tDCS on the working memory Zviadi Aburjania, Herbert Chen network: an fMRI-tDCS study in healthy older adults University of Alabama at Birmingham Nicole Rachel Nissim, Andrew O'Shea, Lindsey Richards, Rachel Telles, Eric Porges Ronald Cohen, Adam J. Woods B211 Improving pilot project application and review University Of Florida Clinical and Translational Science Institute processes: A novel application of Lean Six Sigma in translational science B221 CLARITY Reveals Three Dimensional Morphologies and Susanne Schmidt Hidden Connections of Axonal Bulbs Following Traumatic University of Texas Health Science Center San Antonio Brain Injury John Daniel Arena, Maura T. Weber, John A. Wolf, Rui Xiao, William Stewart, Douglas H. Smith, Victoria E. Johnson University of Pennsylvania School of Medicine

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 37 Poster Abstracts (continued)

B222 The cell-cell adhesion component PLEKHA7 regulates B233 Exploring Gene Expression Signature Shared between the pro-tumorigenic MIR17HG long non-coding RNA in colon Obese Zucker Rat and Human Cardiac Hypertrophy epithelial cells Mackenzie Newman, Janelle Stricker, Han-Gang Yu Mary Catherine Bridges, Joyce Nair-Menon, Antonis Kourtidis West Virginia University Medical University of South Carolina B234 Acellular Hyaluronic Acid Scaffold with Growth Factor B223 CYP2C19*2 and PON1 Q192R polymorphisms are Delivery for Cartilage Repair in a Large Animal Model associated with platelet reactivity to clopidogrel in Puerto Anthony Ryan Martín, Jay M. Patel, Hannah M. Zlotnick, Rican Hispanics with cardiovascular disease Mackenzie L. Sennet, James L. Carey, Robert L. Mauck Dagmar Fredy Hernandez Suarez, Mariana R. Botton, Stuart A. University of Pennsylvania School of Medicine Scott, Matthew I. Tomey, Kyle Melin, Angel Lopez-Candales, Jessicca Y. Renta, Jorge Duconge B235 Functional Characterization of Mutant BRCA1 Icahn School of Medicine at Mount Sinai John Barrows, David Long Medical University of South Carolina B224 A Novel Folate-Receptor Targeted Optical Contrast Agent with Optimized Fluorescence Spectra Can Improve B236 High Intensity Focused Ultrasound (HIFU) can be used Intraoperative Detection of Lung Cancer synergistically with tamoxifen to overcome resistance in Christopher Corbett, Jarrod Predina, Andrew Newton, Michael preclinical and patient derived xenograft models Shin, Lydia Sulyok, Leilei Xia, Philip Low, Sunil Singhal Rachel Sabol, Hakm Murad, Matthew Burow, Damir Khismatullin, University of Pennsylvania School of Medicine Bruce Bunnell Tulane University School of Medicine- LA CaTS B225 Investigation of Patient-Reported Outcomes Following ACL Reconstruction Using Rasch Analysis B238 The role of the CBX8 chromodomain in binding Jenny Hunnicutt, Chris Gregory, Brian Pietrosimone, Chris Katelyn Connelly, Tyler Weaver, Catherine Musselman, Emily Kuenze, Brittany Hand, Craig Velozo Dykhuizen Medical University of South Carolina Indiana University School of Medicine

B239 B226 The Role of TGFβ IN Driving Early Cystic Fibrosis Lung Reversing age-related decline using non-cytotoxic

Disease transplantation of young hematopoietic stem cells Elizabeth L Kramer, William Hardie, Kristin Hudock, Cynthia Michael James Guderyon, Cang Chen, Anidita Bhattachcharjee, Davidson, Alicia Ostmann, John Clancy Xiaogang Wang, Guo Xiaoqian, Sophia Ge, Senlin Li Cincinnati Children's Hospital Medical Center UT Health San Antonio B240 B227 Mental Illness Public Stigma, Culture, and Acculturation Hepatic PPP1R3B deficiency induced reduced hepatic

among Vietnamese Americans insulin signaling results in insulin resistance and NAFLD Mai Do, Do, Jennifer McCleary, Diem Nguyen, Keith Winfrey Swapnil Vijay Shewale, Daniel Rader, Minal M. Mehta, Nicholas Tulane University School of Medicine- LA CaTS J. Hand University of Pennsylvania School of Medicine B228 Reducing mental health stigma to promote treatment B241 adherence Severity of Childhood-onset Systemic Lupus Anne Krendl Erythematosus: Impact of Preceding and Co-existing Indiana University School of Medicine Autoimmune Cytopenias. (Protocol) Ekemini Akan, Shanmuganathan Chandrakasan, Kelly Rouster- B229 Regulation of oncologic signaling pathway by Ikaros Stevens, Laurence Greenbaum, Chelsea Marion, Karli Singer, and Casein Kinase II in Acute Lymphoblastic Leukemia (ALL) Ignacio Sanz, Sampath Prahalad Chandrika Gowda, Chunhua Song, Sinisa Dovat Emory University Penn State Clinical and Translational Science Institute B242 Validation of a novel PD-L1 assay for Bladder Cancer B230 Inhibition of Hyaluronic Acid Synthesis Decreased Circulating Tumor Cells Endometrial Cell Attachment Nicolas Seranio, Louise Aguarin, Jay F. Dorsey, John P. Jennifer Knudtson, Marlen Tellez Santos, Rajeshwar Tekma, Christodouleas, Gary D. Kao Peter Binkley, Jessica McLaughlin, Robert Schenke University of Pennsylvania School of Medicine University of Texas Health Science Center San Antonio B243 Role of macrophage microRNA-150 in age-related B231 L1 Expression Analysis in Adipose Derived Stem Cells macular degeneration Tiffany Kaul, Rachel Sabol, Maria E. Morales, Bruce Bunnell, Jonathan Lin, Harsh Moolani, Abdoulaye Sene, Rohini Sidhu, Prescott Deininger Joseph Lin, Zhenyu Dong, Daniel Ory, Rajendra Apte Tulane University School of Medicine- LA CaTS Washington University in St. Louis, Institute Of Clinical and Translational Sciences B232 miRNA manipulation to improve CFTR correction in cystic fibrosis William Thomas Harris, Farruk Kabir University of Alabama at Birmingham

38 TRANSLATIONAL SCIENCE 2018 B244 Creating a comprehensive municipal inventory of B254 Differentiation of Functional Cardiomyocytes From common ragweed (Ambrosia artemisiifolia) to predict Induced-Pluripotent Stem Cells Derived from Amniotic Fluid allergenic pollen exposures Mallory Lennon, Damon Pool, Patrick Sean McGrath, Ganna Daniel SW Katz, Stuart Batterman Bilousova, Jeffrey G. Jacot University of Michigan School of Medicine University of Colorado at Denver

B245 A Clinically Relevant Rabbit Surgical Model of Pelvic B255 Decreased pulmonary pulse transit is associated with Reconstruction to Evaluate the Immune Response to Novel pediatric pulmonary arterial hypertension Surgical Materials Joshua Chew, Jeffrey G. Weiner, Daniel L. Saurers, Eric D. Aimon Iftikhar, Alexis Nolfi, Pamela Moalli, Bryan Brown Austin, Jason T. Christensen University of Pittsburgh Vanderbilt University Medical Center

B246 What genes are involved in the brain food reward B256 Estimation of cellular glutamine pool size in breast circuitry: Findings from a large candidate gene analysis. cancer by [18F](2S,4R)4-Fluoroglutamine PET: a quantitative Ying Meng, Susan W. Groth, Joyce A. Smith, Harriet Kitzman kinetic approach University of Rochester Medical Center Austin Pantel, Hsiaoju Lee, Shihong Li, Robert Doot, Robert Mach, David Mankoff, Rong Zhou B247 Optimizing a Technique for Visualizing Retinal and University of Pennsylvania School of Medicine Choroidal Blood Flow Noninvasively Paras Vora, Nicholas Bell, Romulo Albuquerque, Jooyoung Cho, B257 Characteristics of Affordable Senior Housing Gregory Botzet Communities Associated with Changes in Older Adults’ Well- University of Kentucky Center for Clinical and Translational Being Science Noah J. Webster, Toni C. Antonucci University of Michigan School of Medicine B248 Using Neural Connectivity Biomarkers to Predict Depressive Symptomatology in Adolescence B258 Does Maternal Schistosomiasis Affect the Humoral and Rajpreet Chahal, David Weissman, Paul Hastings, Richard Cellular Vaccine Responses of Infants? Robins, Rand Conger, Amanda Guyer Deborah Bloch, Taryn McLaughlin, Cheryl Day, W. Evan Secor, University of California, Davis Govert van Dam, Paul Corstjens, Heather B. Jaspan, Grace John- Stewart, Saad B. Omer, Lisa Cranmer B249 Using real-time fMRI neurofeedback as a tool for Emory University demonstrating therapeutic efficacy in Cognitive Behavioral Therapy B259 Physiologically- Based Pharmacokinetic Model Kathryn Dickerson, Katherine E. MacDuffie, Jeff MacInnes, Kari Incorporating Extrahepatic Glucuronidation Predicts M. Eddington,Timothy J. Strauman, R. Alison Adcock Integrase Inhibitor Pharmacokinetics Duke University Brandon Tyler Gufford, Stephanie N. Liu, Jessica Bo Li Lu, Zeruesenay Desta B250 TL1 Team Approach for Cancer Cell to Dendritic Cell Indiana University School of Medicine Conversion in 3D Printed Models S. Tori Ellison, Mathew Sebastian B260 Vesicular secretion of suppressor of cytokine signaling University Of Florida Clinical and Translational Science Institute 3 by alveolar macrophages is dysregulated in NSCLC patients and its provision inhibits epithelial cell B251 Non-redundant roles for immune checkpoint blockade transformation and tumor cell function and agonistic CD40 in mediating T cell responses in Jennifer Speth, Loka R. Penke, Joseph Bazzill, Douglas A. pancreatic ductal adenocarcinoma Arenberg, James J. Moon, Venkateshwar G. Keshamouni, Vibha Alexander Morrison, Katelyn T. Byrne, Robert H. Vonderheide N. Lama, Marc Peters-Golden University of Pennsylvania School of Medicine University of Michigan School of Medicine

B252 Structure-Based Drug Design of Selective Inhibitors for B261 Beyond Diagnosis: Using Ultrasound to Affect Tumor Carbonic Anhydrase IX as a Triple Negative Breast Cancer Vasculature for HCC Therapy Treatment Julia D'Souza, Laith Sultan, Sean Carlin, Terence Gade, Stephen Carrie Lomelino, Akilah Murray, Mam Mboge, Nicole Horenstein, Hunt, Chandra Sehgal Coy Heldermon, Susan Frost, Robert McKenna University of Pennsylvania School of Medicine University Of Florida Clinical and Translational Science Institute B262 Using small molecules to inhibit the ERG-EWS B253 Acute Alcohol Exposure Alters Circulating Cannabinoid interaction in prostate cancer Levels in Humans Taylor Nicholas Tim D. Klepp, Vijay Ramchandani, Rajita Sinha, Honoreé White Indiana University School of Medicine Brewton, Bethany Stangl, Matthew Sloan, Resat Cinar,Laura Kwako, George Kunos National Institutes of Health

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 39 Poster Abstracts (continued)

B263 RNA-nanoparticles to enhance and track dendritic cell B271 Association of Timing and Frequency of Sinus Surgery migration with Lung Transplant Survival in Cystic Fibrosis Adam Grippin, Elias J. Sayour, Brandon Wummer, Adam Tracy Cheng, Tracy Truong, Adam L. Honeybrook, Kevin Choi, Monsalve, Tyler Wildes, Kyle Dyson, Jon Dobson, Duane A. Alice L. Gray, Laurie Snyder, Scott M. Palmer, David W. Jang Mitchell Duke University University Of Florida Clinical and Translational Science Institute B272 Sinus Surgery is Associated with Less Frequent B264 First-trimester depression is not associated with birth Antibiotic Use in Cystic Fibrosis Patients with Lung outcomes in a diverse urban cohort: preliminary results from the Transplant New York University Children’s Environmental Health Study Tracy Cheng, Kevin Choi, Adam L. Honeybrook, Alice Gray, Linda G Kahn, Sara Brubaker, Akhgar Ghassabian, Shilpi S. Laurie Snyder,Scott M. Palmer, David W. Jang, Ralph Abi Mehta-Lee, Lisa M. Nathan, Leonardo Trasande Hachem NYU - H+H Clinical and Translational Science Institute Duke University

B265 Defining the role of PHF19 as a promoter of B273 The effect of antipyretics and fever on the mortality of tumorigenicity and therapeutic target in Plasma Cell mechanically ventilated patients Leukemia and Multiple Myeloma Emily Martin Evans, Rebecca J. Doctor, Brian M. Fuller, Richard Carolina Schinke, Pingping Qu, Sandra Susanibar, Antje Hoering, S. Hotchkiss, Anne M. Drewry Valeriy Lyzogubov, Aneta Mikulasova, Ruslana Tytarenko, Washington University in St. Louis, Institute Of Clinical and Samrat Choudhury, Purvi Patel, Sharmilan Thanendrarajan, Translational Sciences Maurizio Zangari, Faith Davies, Daisy Alapat, Bart Barlogie, Gareth Morgan, Amit Verma, Frits van Rhee, Brian Walker B274 A protocol examining the natural trajectory of upper University of Arkansas Translational Research Institute limb performance after stroke and the role of psychological factors in modifying outcomes B266 Age-related change in 5-HT6 receptor availability in Kimberly Waddell, Rachel Tabak, Michael Strube, Catherine Lang healthy male volunteers measured with 11C-GSK215083 PET Washington University in St. Louis, Institute Of Clinical and Rajiv Radhakrishnan, Nabeel Nabulsi, Jean-Dominique Gallezot, Translational Sciences Beata Planeta, Evan Morris, Yiyun Huang, Richard Carson, David Matuskey, Shannan Henry, Shu-fei Lin, Jim Ropchan, Wendol B275 Metabolic and phenotypic changes in adipocytes (or Williams, Deepak Cyril D’Souza adipocyte progenitor cells) from MDX4CV mice Yale School of Medicine Josiane Joseph, Dong Seong Cho, Jason D. Doles Mayo Clinic B267 Muscling in on the role of homeobox protein Six1 in Rhabdomyosarcoma B276 Apolipoprotein L1 Variant Alleles and Nephritis Risk Jessica Y Hsu, Heide L. Ford, Kristin B. Artinger Traits in Ghanaian SLE Patients University of Colorado at Denver Ashira D. Blazer NYU - H+H Clinical and Translational Science Institute B268 The effects of autoimmune inflammation on proliferation, differentiation, and androgen receptor signaling B277 Role of tissue non-specific alkaline phosphatase in adult prostate stem cells (TNAP) in promoting the survival of acute myeloid leukemia Paula Cooper, Hsing-Hui Wang, Meaghan Broman, Hristos (AML) cells within the bone marrow microenvironment Kaimakliotis, Scott Crist, Nadia Atallah, Majid Kazemian, Bennett Bradley Bowles, Rosalie M. Sterner, Kimberly N. Kremer, Amel Elzey,Liang Cheng, Timothy L. Ratliff, Emery Goossens Dudakovic, Jennifer J. Westendorf, Andre J. Van Wijnen, Karen Indiana University School of Medicine E. Hedin Mayo Clinic B269 Longitudinal Changes in EEG Power Envelope Connectivity are Proportional to Motor Recovery in Chronic B278 The use of Mirrorball technology to conduct high- Stroke Patients throughput screening on cell-based fluorescence assay Joseph Benjamin Humphries, David T. Bundy, Eric C. Leuthardt, Manisha Pradhan, Kirill Gorshkov, Miao Xu, Shu Yang, Min Shen, Thy N. Huskey Wei Zheng Washington University in St. Louis, Institute Of Clinical and National Institutes of Health Translational Sciences B279 Designing for Dissemination: Characteristics of CTSA B270 A TL1 Team Approach to Evaluating Novel Hubs as Adopters of Clinical and Translational Science Antimicrobial Compounds against Mycoplasmas and their Innovation Interaction with Drug Metabolizing Enzymes Elaine H. Morrato, Lindsay Lennox, Anne Schuster Marissa Valentine-King, Katherine Cisneros, Margaret O. James, University of Colorado at Denver Robert W. Huigens III, Mary B. Brown University Of Florida Clinical and Translational Science Institute

40 TRANSLATIONAL SCIENCE 2018 B280 Assessing the intersection of social-biological process B289 Metformin Regulates Metabolic and Non-Metabolic in Dengue virus infection in Marginalized, Affected Pathways in Skeletal Muscle and Subcutaneous Adipose Communities of Ecuador Tissues of Older Adults Denisse M. Vega Ocasio, Craig Morrell, Anna M. Stewart Ibarra, Ameya Kulkarni, Erika Brutsaert, Valentin Anghel, Kehao Zhang, Sanjay B. Maggirwar, Kevin Fiscella, Timothy De Ver Dye Jessica Mar, Meredith Hawkins, Jill Crandall, Nir Barzilai University of Rochester Medical Center Albert Einstein College of Medicine

B281 The use of circulating tumor cell technology for the B291 The Empower Lab: An Innovative Model for Research characterization of tumor cells and assessment of PD-L1 Experience and Training for Undergraduate, Graduate, and expression in pleural effusions of metastatic non-small cell Medical Students lung cancer patients Veronica Ades, Anna Chessky, Ydelsie Vasquez, Emily Jeffrey Thompson, Ryan Fan, Samantha L. Savitch, Stephanie S. Rabinowitz Yee, Christian A. Powers, Gordon Yu, Lauren Gebrian, Chandra New York University General Clinical Research Center Rao, Steve Gross, Michael Feldman, Anil Vachani, Erica L. Carpenter B292 Neonatal white matter microstructure is associated with University of Pennsylvania School of Medicine cerebral palsy at 2 years of age Stephanie Merhar, Elveda Gozdas, Jean Tkach, Nehal Parikh, B282 Analysis of genetic risk factors associated with the Beth Kline-Fath, Weihong Yuan, Scott Holland development of cerebral microbleeds, a marker of poor Cincinnati Children's Hospital Medical Center neurocognitive function in pediatric patients with brain tumors B293 Assessing ganglion cell layer topography in human Lennox Byer albinism using optical coherence tomography University of California, San Francisco Erica N. Woertz, Bisola Omoba, Stephanie J. Chiu, Sina Farsiu, Joseph Carroll B283 Cutaneous Lupus Erythematosus Patients have Medical College of Wisconsin Increased Circulating Myeloid-derived Suppressor Cells with Immunosuppressive Properties B294 Role of orbitofrontal cortex in social-enhanced safety Stephanie Florez-Pollack, Lin-chiang Tseng, Masato Kobayashi, learning and TBI-induced psychosocial deficits in rats Benjamin F. Chong, Kiyoshi Ariizumi Katharine D. Andrews, Elizabeth A. Lungwitz, Amy D. Dietrich, University of Texas Southwestern Medical Center Sreeparna Majumdar, William A. Truitt, Nicholas S. Race, Riyi Shi Indiana University School of Medicine B284 The gut microbiome as a risk factor for Tuberculosis infection and disease B295 Addressing disorganized speech in Serious Mental Matthew F. Wipperman, Charles K. Vorkas, Daniel W. Fitzgerald, Illness through novel assessment and targeted intervention Marc Antoine Jean Juste, Ying Taur, Sivaranjani Namasivayam, Matthew Marggraf, Kyle S. Minor, Claire Draucker, Frank Rudzicz Alan Sher, James M. Bean, Vanni Bucci,Michael S. Glickman Indiana University School of Medicine Weill Cornell Medicine, Clinical and Translational Science Center B296 Innovative physiologic recording skin patch sensors as B285 Hippocampal Network Disruption in Early Amyloid a substitute for continuous heart rate and blood pressure Pathology monitoring in the Neonatal Intensive Care Unit Adam Caccavano, Stefano Vicini Alina Rwei, John A. Rogers, Ha Uk Chung, Shuai Xu Georgetown - Howard Universities Northwestern University

B286 Increasing butyrate levels by microbial manipulation or B297 Disparities in Navigation to Health Research among drug administration to delay Parkinson’s disease Floridians progression. Linda B. Cottler, Deepthi S Varma, Krishna Vaddiparti, Catherine Stephanie M. Garcia, Wenbo Zhou, Curt R. Freed Striley University of Colorado at Denver University Of Florida Clinical and Translational Science Institute

B287 Comparison of Preterm and Term Wharton’s Jelly- B298 Ultra-low Na18F Tracer Dosing for Preclinical Skeletal Derived Mesenchymal Stem Cell Properties in Differing Imaging Enables New Concepts in Digital PET/CT Oxygen Tensions Maria Isabel Menendez, Richard Moore,Katherine Binzel, Michael Alvaro Moreira, Saloni Agarwal, Cailtyn Winter, Alexis Corral, Friel, Jun Zhang, Rebecca Jackson, Michael Knopp Peter Hornsby, LuZhe Sun The Ohio State University University of Texas Health Science Center San Antonio B299 Proteomics in the early diagnosis of Metabolic B288 PRMT5 is a master epigenetic regulator to promote Syndrome in a Hispanic pre-teen cohort repair of radiation-induced DNA damage Guillermo Torres Viera, Ángel Lopez Candales, Horacio Serrano Jake L. Owens Rivera Indiana University School of Medicine University of Puerto Rico-Medical Sciences Campus

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 41 B300 Noninvasive Biomarkers for Inflammatory Bowel Disease: Drawbacks and Potential Vihang Patel, Sherif Seif, Terrence Barrett University of Kentucky Center for Clinical and Translational Science

B301 Diagnostic accuracy of a blood-based biomarker panel for colorectal cancer detection Elba V. Caraballo, Marcia Cruz-Correa, Willy Ramos, Luis Carvajal University of Puerto Rico-Medical Sciences Campus

B302 Development of human cell-based screening assays to detect subject-specific drug-response variability Francesca Stillitano, Joshua Mayourian, Jaydev Dave, Jean- Sébastien Hulot, Roger J. Hajjar Icahn School of Medicine at Mount Sinai

B303 Alleviating the Psychological Stress on Therapeutic Outcome in Breast and Colon Cancer using Medicinal Plant Extracts Kristina Andrijauskaite, Michael Wargovich University of Texas Health Science Center San Antonio

B304 Natural History of Neotissue Formation in a Murine Model of Tissue-Engineered Heart Valves Joseph David Drews, Tai Yi, Hideki Miyachi, Kevin Blum, Poster Abstracts (continued) Christopher Breuer The Ohio State University

B300 Noninvasive Biomarkers for Inflammatory Bowel B305 Hatha Yoga in Latino Preschool Children with Disease: Drawbacks and Potential Oppositional Defiant Disorder Vihang Patel, Sherif Seif, Terrence Barrett Alisha M Subervi-Vazquez, Karen G Martinez, Maribel Matos, University of Kentucky Center for Clinical and Translational Anna E. Esparham, Annette Tomey Science University of Pennsylvania School of Medicine

B301 Diagnostic accuracy of a blood-based biomarker panel B306 High concentrations of CXCL12 decrease pancreatic for colorectal cancer detection adenocarcinoma growth Elba V. Caraballo, Marcia Cruz-Correa, Willy Ramos, Luis Emily Vonderhaar, Michael Dwinell, Ishan R. Roy, Donna M. Carvajal McAllister University of Puerto Rico-Medical Sciences Campus Medical College of Wisconsin

B302 Development of human cell-based screening assays to B307 Characterizing the Expression Kinetics of HIV-1 detect subject-specific drug-response variability Envelope Protein Francesca Stillitano, Joshua Mayourian, Jaydev Dave, Jean- Djin-Ye Oh, Lihong Liu, Benjamin Trinité, En-Wei Hu-Van Wright, Sébastien Hulot, Roger J. Hajjar Vincent Sahi, Yaoxing Huang, David N. Levy, David D. Ho Icahn School of Medicine at Mount Sinai Rockefeller University

B303 Alleviating the Psychological Stress on Therapeutic B308 A Systematic Overview of Cost-Utility Analyses in Outcome in Breast and Colon Cancer using Medicinal Plant Dermatology Extracts David G Li, Adam Faletsky, Peter Neumann, Joshua Cohen Kristina Andrijauskaite, Michael Wargovich Tufts University School of Medicine University of Texas Health Science Center San Antonio

B304 Natural History of Neotissue Formation in a Murine Model of Tissue-Engineered Heart Valves Joseph David Drews, Tai Yi, Hideki Miyachi, Kevin Blum,

Christopher Breuer The Ohio State University

B305 Hatha Yoga in Latino Preschool Children with

Oppositional Defiant Disorder Alisha M Subervi-Vazquez, Karen G Martinez, Maribel Matos, NotesAnna E. Esparham, Annette Tomey University of Pennsylvania School of Medicine

B306 High concentrations of CXCL12 decrease pancreatic adenocarcinoma growth Emily Vonderhaar, Michael Dwinell, Ishan R. Roy, Donna M. McAllister Medical College of Wisconsin

B307 Characterizing the Expression Kinetics of HIV-1 Envelope Protein Djin-Ye Oh, Lihong Liu, Benjamin Trinité, En-Wei Hu-Van Wright,

Vincent Sahi, Yaoxing Huang, David N. Levy, David D. Ho Rockefeller University

B308 A Systematic Overview of Cost-Utility Analyses in Dermatology David G Li, Adam Faletsky, Peter Neumann, Joshua Cohen Tufts University School of Medicine

42 TRANSLATIONAL SCIENCE 2018 2018 Joint Annual Meeting Program Committee

Thank you to the following individuals for volunteering their time, knowledge, and energy during the planning process for Translational Science 2018.

COMMITTEE CHAIRS COMMITTEE MEMBERS Curt Civin, MD, University of Maryland Susan Perkins, PhD, Indiana University School of Medicine School of Medicine Milton Eder, MD, University of Minnesota Thomas Perorazio, PhD, University of Scott Steele, PhD CTSI Committee Member Michigan University of Janice Gabrilove, MD, FACP Icahn School Kathryn Sandberg, PhD, Georgetown - Rochester of Medicine at Mount Sinai Howard Universities Medical Center Robert Kimberly, MD, University of Michael Schivo, MD, MAS, University of Alabama at Birmingham California, Davis Michael Liebman, PhD, IPQ Analytics Iuliana Shapira, MD, SUNY Downstate Medical Center Siobhan McMahon, PhD, MPH, GNP-BC, University of Minnesota CTSI Stephen Sugrue, PhD, University of Florida William Lowe, MD Emma Meagher, MD, University of Karen Weavers, M. Ed., Mayo Clinic Northwestern Pennsylvania School of Medicine Anthony Windebank, MD, Mayo Clinic University Carol Merchant, MD, MPH, National Cherry Wongtrakool, MD, Emory Institutes of Health University

FREE WIFI

Network Name: MARRIOTT_CONFERENCE Download the Password: TS18 Translational Science Meeting App Enhance your Translational Science 2018 experience by downloading the mobile app. It’s your go-to resource for information about the schedule, sessions, and speakers. Search “Translational Science Meeting” in the Apple or Android store. Once it’s downloaded, choose “Translational Science 2018” from the show list and tap download.

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 43 Partnering Organizations

ASSOCIATION FOR CLINICAL AND TRANSLATIONAL SCIENCE

ACTS BOARD OF DIRECTORS President Emma A. Meagher, MD University of Pennsylvania Perelman School of Medicine

Past-President Harry P. Selker, MD, MSPH Tufts University Clinical and Translational Science Institute

President-Elect Robert P. Kimberly, MD University of Alabama at Birmingham

Secretary SEE A TL1 GOLD OR BLUE RIBBON? Fred Meyers, MD, MACP Professor of Medicine Gold Ribbon Awards represent the top 10 percent of all abstracts submitted by Treasurer TL1 trainees as first author. They will be David Center, MD giving oral presentations at Translational Director, Boston University Translational Science Institute Science 2018.

MEMBERS Blue Ribbon Awards represent the top Mark Robert Burge, MD George A. Mashour, MD, PhD 25 percent of trainees in their TL1 trainee University of New Mexico University of Michigan program who submitted abstracts as first Health Sciences Center Gary Rosenthal, MD author to Translational Science 2018. Gayathri Devi, MS, PhD Wake Forest Baptist Duke University School of Medical Center The TL1 Top Poster Presenter Awards will be Medicine Kathleen R. Stevens, RN, determined by a panel of judges who will Vicki Ellingrod, MS, EdD, ANEF, FAAN score Blue Ribbon Awardees based on Pharm.D.FCCP University of Texas Health three criteria which includes the science, University of Michigan Science Center San Antonio 4 minute presentation with a 2 min Q&A Estela Estape, PhD and poster layout. University of Puerto Rico, Robert Toto, MD Medical Sciences Campus University of Texas Southwestern Medical Katherine E. Hartmann, MD, Center PhD Vanderbilt University Journal of Clinical and Medical Center Translational Science Editor Christopher John Lindsell, Arthur M. Feldman, MD, PhD PhD Lewis Katz School of Vanderbilt University Medicine at Temple Medical Center University

44 TRANSLATIONAL SCIENCE 2018 AAAS BOARD OF DIRECTORS AAMC BOARD OF DIRECTORS Chair Chair Barbara A. Schaal, PhD M. Roy Wilson, MD Washington University in St. Louis Wayne State University

President Chair-Elect Susan Hockfield, PhD Lilly Marks Massachusetts Institute of Technology University of Colorado

President-Elect Immediate Past Chair Margaret Hamburg, MD Marsha D. Rappley, MD National Academy of Medicine Virginia Commonwealth University

Treasurer President and CEO Carolyn Ainslie Darrell G. Kirch, MD Princeton University Association of American Medical Colleges

CEO MEMBERS Rush D. Holt Executive Publisher, Science Kirk A. Calhoun, MD Mary D. Nettleman, MD, MS University of Texas Health University of South Dakota Northeast MEMBERS Daniel K. Podolsky, MD Scott D. Gitlin, MD University of Texas Cynthia M. Beall Laura H. Greene University of Michigan Southwestern Medical Case Western Reserve National High Magnetic Center University Field Laboratory, Florida Daniel A. Hashimoto, MD, MS State University Massachusetts General Gabriela K. Popescu, May R. Berenbaum Hospital PhD, MS University of Illinois, Urbana- Kaye Husbands Fealing University at Buffalo Champaign Georgia Institute of J. Larry Jameson, MD, PhD Technology University of Pennsylvania Elizabeth L. Travis, PhD, MEd Stephen P.A. Fodor The University of Texas MD 13.8, Inc. Robert B. Millard Beverley H. Johnson Anderson Cancer Center MIT Corporation Institute for Patient- and S. James Gates, Jr. Family-Centered Care Thomas R. Viggiano, Mercedes Pascual Brown University MD, MEd University of Chicago Joseph E. Kerschner, MD Michael S. Gazzaniga Mayo Medical School Medical College of University of California, William D. Provine Wisconsin Marie C. Walters, MS Santa Barbara DuPont/Delaware Wright State University Innovation Space Alicia D. H. Monroe, MD Baylor College of Medicine

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 45 Partnering Organizations (continued)

AFMR NATIONAL COUNCIL CR FORUM BOARD OF DIRECTORS

President Chair-Elect, AFMR Chairman Florence Rothenberg, MS, Southern Section Harry P. Selker, MD, MSPH MD, FACC Dana Rizk, MD Tufts Medical Center University of Cincinnati Secretary-Treasurer, AFMR Vice Chairman Southern Section President-Elect Herbert Pardes, MD Viranuj Sueblinvong, MD Suthat Liangpunsakul, MD New York-Presbyterian Hospital Indiana University School of Chair, Eastern Section Medicine Allison Reiss, MD Secretary-Treasurer William L. Lowe, Jr., MD Chair-Elect, AFMR Eastern Immediate Past President Northwestern University Feinberg School of Medicine Armand Krikorian, MD, Section FACE Oana Sandu, MD MEMBERS Chair of the Western Past President Lars Berglund, MD, PhD Rebecca Jackson, MD Region Amir A. Zeki, MD, MAS University of California, The Ohio State University Amir Goldkorn, MD Davis School of Medicine Secretary-Treasurer E. Albert Reece, MD, PhD, Leticia Ryan, MD, MPH Chair-Elect of the Western Robert M. Califf, MD, MACC MBA Region Duke University School of University of Maryland Vice President of Kevin D. Deane, MD, PhD Medicine School of Medicine Meetings and Programs Michael Schivo, MD, MAS Chair, AFMR Midwest Barry S. Coller, MD Arthur H. Rubenstein, Section The Rockefeller University MBBCh Editor-in-Chief Dawn B. Davis, MD, PhD University of Pennsylvania Anne B. Curtis, MD Michael J. McPhaul, MD Health System Chair-Elect, AFMR University at Buffalo Councilor-at-Large Midwest Section School of Medicine and Robert Sherwin, MD Kieren Mather, MD Vijay Shivaswamy, MBBS, Biomedical Sciences Yale School of Medicine MS Secretary-Treasurer of the Pamela Davis, MD, PhD Anantha Shekhar, MD, PhD Western Region Councilor-at-Large Case Western Reserve Indiana University School of Samrat U. Das, MD Iuliana Shapira, MD University Medicine

Secretary-Treasurer, AFMR Councilor-at-Large Maurizio Fava, MD Midwest Section Sharma Prabhakar Massachusetts General EX OFFICIO MEMBERS Joumana Chaiban, MD Hospital and Harvard Daniel E. Ford, MD, MPH Secretary-Treasurer, AFMR Medical School Chair, AFMR Southern Eastern Section Johns Hopkins University School of Medicine Section Akankasha Goyal, MD Arthur Feldman, MD, PhD Abeer Moanna, MD Lewis Katz School of John I. Gallin, MD Membership Committee Medicine at Temple National Institutes of Health Chair University Edgar Lerma, MD Harry B. Greenberg, MD Stanford University School of Medicine

46 TRANSLATIONAL SCIENCE 2018 Continuing Medical Education

Jointly provided by Postgraduate Institute for Medicine and ACTS.

TARGET AUDIENCE DISCLOSURE OF CONFLICTS OF INTEREST The annual meeting is intended for physicians, Postgraduate Institute for Medicine (PIM) requires registered nurses, nurse practitioners, fellows, and instructors, planners, managers and other individuals residents who engage in the care of patients and who are in a position to control the content of this deliver primary care to adolescents and adults. activity to disclose any real or apparent conflict of interest (COI) they may have as related to the content EDUCATIONAL OBJECTIVES of this activity. All identified COI are thoroughly vetted After attending this event, participants should be and resolved according to PIM policy. The existence better able to: or absence of COI for everyone in a position to control • Identify current examples of best practices in clinical content will be disclosed to participants prior to the and translational research start of each activity.

• Describe current initiatives to advance translational HOW TO RECEIVE YOUR CME/CE CERTIF- science education and research priorities ICATE / STATEMENT OF PARTICIPATION • Identify current methods for educating and training We support green CME by offering your request for clinical and translational researchers CME/CE credit online. In order to obtain your CME/ CE certificate, please follow the steps below at the JOINT ACCREDITATION STATEMENT conclusion of the meeting: In support of improving 1. Go to www.cmeuniversity.com patient care, this activity 2. Register or login (will take less than 1 minute) has been planned and implemented by the 3. Type in 13056 at the top of the page, “Find Post-Test/ Postgraduate Institute Evaluation by Course”, click enter for Medicine and ACTS. 4. Click on activity title when it appears Postgraduate Institute for Medicine is jointly accredited 5. Choose the type of credit you would like by the Accreditation Council for Continuing Medical 6. Complete online evaluation Education (ACCME), the Accreditation Council for 7. Receive an immediate CME certificate to download Pharmacy Education (ACPE), and the American and/or print for your files Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. If you have any questions regarding the CME certification for this activity, please, contact The Postgraduate Institute for Medicine designates this Postgraduate Institute for Medicine, at inquiries@ live activity for a maximum of 17 AMA PRA Category pimed.com, or call 303-799-1930. 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 47 Event Floor Plans

EXHIBITION LEVEL

FB XIT EXIT E EXIT FBFB

1010' CORRIDOR 9' FE

E EEE E 1010' FP 9'-29''- " FB

1010'

FP 1212' FB FB 1010' IT FFBB 18' E FPFP 5'5'--11" 8'-33" EX E E 1010' FPP 10100''-9"

6 E 16' I D D T E N O E 8'8' D HEALTH EQ T D 1212' P T A P O 46 DOUBLE-SIDED POSTER BOARDS BOARDS L O O S S S T 15 SINGLE-SIDED POSTER BOARDS RDS 1010' I D T E R FPP E 107 TOTAL SIDES E R 12 DOUBLE-SIDED POSTER BOARDS R S B I B N 24 TOTOTATALL SISIDEDES O OA A G R R D D FFSS FB S EXIT EXIT FP 1212' S FB EXIT FP STAIR FP ROOSEVELT 4

EXIT 24' x 55' EXIT FB

EXIT CEILING: 11' T XI

.E FB EX EE 1212' EXIT

POSTER HALL 131 DOUBLE-SIDED POSTER BOARDS

STACK STAIR CLOSE 54 SINGLE-SIDED POSTER BOARDS EX. EXIT 316 TOTAL SIDES FB

AV EEE Navigating the Hall by Poster Track CLOSET FE FB CORRIDOR ROOSEVELT 3 EXIT CR Forum Top Ten & ACTS Oral Abstracts, 1-70 26' x 54'  CEILING: 11' EXIT AV Biomedical Informatics/Health Informatics/Digital Health/ CLOSET  FB FB EE E Social, A/B 71-88 STAIR

FB EXIT Education/Mentoring/Professional & Career Development, ROOSEVELT 2  BIOMEDICAL 26' x 54' A/B 89 -113 EXIT CEILING: 11' 4 DOUBLE-SIDED POSTER BOARD 9 SINGLE-SIDED POSTER BOARDS STAIR 17 TOTAL SIDES FB Health Equity & Community Engagement, A/B 114-136 F  EE E F

 Science & Health Policy/Ethics/Health Impacts/Outcomes ROOSEVELT 1 EXIT T Research, A/B 137-170 I T EX FP EXIT 26' x 54' FE EXI FE CEILING: 11' Clinical Epidemiology/Clinical Trial, A/B 171-205 STAIR FB FB E 101 '  Basic/Translational Science/Team Science, A/B 206-308 FE FP XIT 1'-7" E FP FB FB EXIT STAIR EXIT EXIT T FP ELEV EXIT LOBBY B FE 31 8 FE ELEV CORRIDOR

8'8' ELEV STAIR

C 8'8' LOBBY XIT 8'-11"8'-11" E EXIXITIT 48 TRANSLATIONAL SCIENCE 2018 LOBBY LEVEL

MEZZANINE LEVEL

EXPLORE, COLLABORATE, EDUCATE, INNOVATE 49 Join us for TRANSLATIONAL SCIENCE 2019

March 6-8, 2019 Washington Marriott Wardman Park Washington, DC