Canada-Us Health Summit 2015
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CURRICULUM VITAE SHERRY A. GLIED September 7, 2012 Harvard University, Ph.D., Economics, 1990 Dissertation: the Economics of He
Glied CURRICULUM VITAE SHERRY A. GLIED September 7, 2012 ACADEMIC TRAINING Harvard University, Ph.D., Economics, 1990 Dissertation: The Economics of Health Status and Labor Market Outcomes. Ann Arbor, Michigan: University Microfilms International, 1991. Sponsor: David E. Bloom University of Toronto, M.A., Economics, 1985 Yale University, B.A., Economics, 1982 ACADEMIC AND PROFESSIONAL APPOINTMENTS August 2012 - current Professor Department of Health Policy and Management Mailman School of Public Health Columbia University July 2010 – August 2012 Assistant Secretary for Planning and Evaluation Office of the Secretary U.S. Department of Health & Human Services July 2002-June 2010 Professor and Chair (through September 2009) (currently on leave) Department of Health Policy and Management Mailman School of Public Health Columbia University July 1998-July 2002 Associate Professor and Chair Department of Health Policy and Management Joseph L. Mailman School of Public Health Columbia University 1 Glied September 2000 Visiting Faculty University of Toronto Law School January 1991-June 1998 Assistant Professor of Public Health Division of Health Policy and Management Columbia School of Public Health July 1991 – June 1998 Assistant Professor of Economics Columbia University August 1996 – July 1997 Visiting Assistant Professor Department of Health Care Policy Harvard Medical School September 1989 – December 1990 Associate in Public Health Division of Health Policy and Management Columbia School of Public Health PROFESSIONAL ORGANIZATIONS AND SOCIETIES American College of Healthcare Executives American Economics Association AcademyHealth American Public Health Association Association for Public Policy and Management Professional Appointments January 1999-September 2009: Member, MacArthur Foundation Initiative on Mental Health Policy Research February 1993 – May 1993: Co-Chair, Global Budgets and Economic Impacts Working Groups, The President’s Health Care Task Force, Washington, D.C. -
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“Building on Foundations of Innovation” #NAI2016 Addressing Problems Worth Solving The challenges we are confronting worldwide are both complex and daunting. In the next 20 years, the most important inventions will be those that address critical social and environmental issues, reaching and serving communities with the greatest needs. These inventions will deliver meaningful change, solve urgent problems, and create sustainable economic value for all. The Lemelson Foundation focuses on problems that are worth solving—and not simply problems that can be solved. We recognize the need for a strong supportive invention ecosystem to make this happen. We seek to inspire inventors to know that they can make a difference. We work to ensure that the next generation of inventors can become agents of positive change. Find out more about how we provide support to foster inventions to improve lives at: www.lemelson.org/impactinventing TABLE OF CONTENTS Welcome Letter from the NAI President .......... 2 Summary Conference Agenda ........................... 3 Detailed Conference Agenda ..........................4-9 About the NAI ................................................... 10 NAI Board of Directors & Officers ................. 11 Conference Program Committee .................... 11 NAI Federal Charter ......................................... 12 Q & A About H.R. 849 ...................................... 13 Elected 2015 NAI Fellows ................................ 14 “Building on Presenter & Speaker Biographies .............. 15-28 Meet the NAI Staff ....................................... 29-30 Foundations of Innovation” Sustaining Member Institutions ................ 31-32 Member Institution Representatives ......... 33-35 or the fifth anniversary meeting, we celebrate the American spirit F Maps of Conference Venue Locations ...... 36-38 of ingenuity with the theme “Building on Foundations of Innovation.” Throughout the conference program, we will explore the interaction Thank you to Our Sponsors ...................... -
The Mapping and Characterization of a Novel Binding Site on HIV-1 Gp120 for The
The mapping and characterization of a novel binding site on HIV-1 gp120 for the broadly neutralizing monoclonal antibody IgG1 b12 by Jillian Waruk A Thesis submitted to the Faculty of Graduate Studies of The University of Manitoba in partial fulfilment of the requirements of the degree of DOCTOR OF PHILOSOPHY Department of Medical Microbiology University of Manitoba Winnipeg Copyright © 2011 by Jillian Waruk Abstract HIV infects target cells via fusion events following surface envelope glycoprotein binding to the CD4 receptor and a chemokine co-receptor. Despite the high sequence variability of envelope across and within HIV-1 subtypes, this process requires conserved sequences and structures on gp120, which also represent good targets for HIV-1 neutralizing antibodies. Few examples of HIV-1 broadly neutralizing antibodies exist, but these antibodies may hold the key to a protective HIV-1 vaccine. One such antibody, IgG1 b12 (b12), binds the CD4 binding site on the HIV-1 envelope glycoprotein gp120. To date, no vaccine preparations have been able to elicit a b12-like response. A complete understanding of the mechanism of b12 binding to gp120 is essential to successful design of an b12-like immune response. Until now, strategies to map the b12 binding site on gp120 have utilized indirect techniques and/or core gp120 and have shown that b12 binds to a site on gp120 that overlaps the CD4 binding site. To more directly map the b12 epitope on intact gp120, epitope excision mass spectrometry mapping was carried out in the MALDI QqTOF platform. The putative epitope sequence was confirmed by tandem mass spectrometry sequencing. -
Worldrenowned HIV Researcher Frank Plummer, 67, Dies
2/5/2020 Worldrenowned HIV researcher Frank Plummer, 67, dies BBC News Home News Sport Reel Worklife Travel Future Worldrenowned HIV researcher Frank Plummer, 67, dies 5 hours ago BROOKE WEDLOCK/UNIVERSITY OF MANITOBA Frank Plummer, a "scientific maverick" whose research had a profound impact on global public health, has died. The worldrenowned microbiologist was most widely recognised for his groundbreaking work on understanding HIV transmission. Dr Plummer, 67, was also recognised for leadership roles in the Sars, H1N1 flu and Ebola epidemics. He had recently spoken publicly about undergoing experimental brain surgery to treat alcoholism. The researcher died while in Kenya to celebrate the 40th anniversary of a research collaboration between the University of Manitoba and University of Nairobi, reportedly of a heart attack. "Today we lost a giant," said Dr Brian Postl, a former classmate of Dr Plummer's at the University of Manitoba. "Back in medical school, Frank was clearly a creative thinker and amongst our accomplished MD Class of 1976, distinguished himself as a true leader and visionary." https://www.bbc.com/news/worlduscanada51317386 1/6 2/5/2020 Worldrenowned HIV researcher Frank Plummer, 67, dies BBC News Dr Digvir Jayas, of the University of Manitoba, said Dr Plummer's "contributions have had a cumulative global impact on saving the lives of tens of thousands of people for decades and also improving the lives of HIVpositive people around the world". Among his findings was that HIV could be transmitted between mothers and babies through breast milk. He also did work with Nairobi sex workers, showing that a small percentage of them showed an immunity to the disease. -
Commentary Motivating Action Why Should Canadian Physicians Participate in Research, Education, Or Patient Care in the Developing World?
Commentary Motivating action Why should Canadian physicians participate in research, education, or patient care in the developing world? Peter A. Singer MD MPH FRCPC FRSC he worries facing my kids, and probably yours, Ethics include things like the following: Will they get to One of the greatest ethical challenges in the world is the Ttheir squash game on time? Should they take hip- inequity in global health. In industrialized countries, life hop or jazz dance classes? Which summer camp should expectancy is 80 years and rising; in many parts of the they attend? Will they get into their university of choice? developing world, especially in Africa and particularly as At the same time, millions of parents and kids around a result of HIV and AIDS, it’s 40 years and falling. I spent the world are facing a much more serious set of con- 10 years leading the University of Toronto’s Joint Centre cerns: Will they have sufficient food to feed their fami- for Bioethics. There, my colleagues and I addressed a lies? What will they do if one of the children gets sick? wide range of clinical ethics issues—consent, end-of- Can they afford to send their kids to school? life care, research ethics, and the like—that confront The difference between these sets of questions might Canadian physicians on a daily basis. While these issues explain why the Council of Science Editors has orga- are important, they somehow do not rise to the same nized a Global Theme Issue on Poverty and Human significance as the inequities in global health. -
Proviral HIV-1 Hypermutation: the Correlation of APOBEC3G/F and HIV-1 Vif in HIV-1 Disease Progression
Proviral HIV-1 Hypermutation: The Correlation of APOBEC3G/F and HIV-1 Vif in HIV-1 Disease Progression by Sujata Monika De A thesis submitted to the Faculty of Graduate Studies of The University of Manitoba In partial fulfilment of the requirements of the degree of MASTER OF SCIENCE Department of Medical Microbiology and Infectious Diseases University of Manitoba Winnipeg, Manitoba Copyright © 2011 by Sujata M. De Abstract APOBEC3 proteins, in particular APOBEC3G/F, are important innate host factors that contribute to protection from HIV-1 infection by inducing high levels of guanine to adenine nucleotide substitutions (termed hypermutation) during HIV-1 viral replication. These nucleotide substitutions occur at different rates and locations across the HIV-1 genome and are thought to be particularly more frequent in the pol region. The virus has evolved ways to counteract these host factors by inducing degradation of APOBEC3G/F proteins through protein interactions with HIV-1 Vif. The aim of this thesis is to characterize and investigate the role of APOBEC3G/F-mediated hypermutation in the HIV-1 genome. We identified a subset of women from the Pumwani Commercial Sex Worker (CSW) cohort with significantly higher rates of hypermutated proviruses in pol. This degree of hypermutation correlated to less severe HIV disease progression as measured by CD4+ T cell count. This was in agreement with previous studies that evidence of APOBEC-mediated hypermutation correlate with reduced disease progression, confirming APOBEC3G/F proteins role in HIV-1 disease. Furthermore, we investigated the in vitro and ex vivo interaction between HIV-1 Vif and APOBEC3G from subjects infected with hypermutated and non-hypermutated proviruses. -
Ralph J. Cicerone
Honoring the Life of Ralph J. Cicerone F RIDAY , A PRIL 2 8 , 2 0 1 7 Fred Kavli Auditorium National Academy of Sciences 210068_Broch.indd 1 8/22/17 3:32 AM 210068_Broch.indd 2 8/22/17 3:32 AM Table of Contents 2 Welcome on Behalf of the National Academy of Sciences MARCIA K. MCNUTT, National Academy of Sciences 3 A Letter in Appreciation SENATOR LAMAR ALEXANDER 5 A Principled Visionary and a Truly Wonderful Guy C. D. (DAN) MOTE, JR., National Academy of Engineering 6 On Behalf of the National Academy of Medicine VICTOR J. DZAU, National Academy of Medicine 8 On Behalf of the Council of the National Academy of Sciences DIANE E. GRIFFIN, Johns Hopkins Bloomberg School of Public Health 10 On Behalf of the National Research Council and its Staff BRUCE B. DARLIng, National Academy of Sciences and National Research Council 13 Scientific Legacy and a Long Friendship VEERABHADRAN RAMANATHAN, University of California, San Diego 15 Far-reaching Impacts on Science JANE LUBCHENCO, Oregon State University 17 When You Come to a Fork in the Road PHILIP NEEDLEMAN, Washington University 20 Fostering the Next Generation of Scientists SUSAN E. TRUmbORE Max Planck Institute for Biogeochemistry and University of California, Irvine 23 Impact on Science Policy as Scientist and President of the NAS JOHN P. HOLDREN, Harvard University 25 The International Science Community MARTIN REES, Cambridge University and Royal Society 27 Character: A Steady Guide in Science and Science Policy HAROLD T. SHAPIRO, Princeton University 29 A Man of History DANIEL J. KEvlES, Yale University, Emeritus 31 On Behalf of his Family CAROL AND SARA CICERONE 1 210068_Broch.indd 3 8/22/17 3:32 AM On Behalf of the National Academy of Sciences MARCIA K. -
A Brief History of ICID
WHOWHO CollaboratingCollaborating CentreCentre forfor ArbovirusArbovirus andand HemorrhagicHemorrhagic FeverFever ReferenceReference andand ResearchResearch Meeting of Collaborating Centres and Dengue National Reference laboratories for the Americas, June 10-12, 2008, Panama Harvey Artsob, PhD Director, Zoonotic Diseases and Special Pathogens Program National Microbiology Laboratory, Public Health Agency of Canada, WHO Collaborating Centre for Arboviruses and Hemorrhagic Fever Reference and Research 1995-2008 1. Virology Laboratory – Ottawa, Ontario 1995-98 Arbovirus diagnostic/reference services, field studies, molecular diagnostics 2. Canadian Science Centre for Human and Animal Health – Winnipeg, Manitoba 1998-2008 Major program expansion, level 3 and 4 laboratories, clean and high containment insectories. Development of viral hemorrhagic fever and emergency response programs. Involvement in international outbreak responses. WHO Collaborating Centre - Redesignation Pending The WHO Collaborating Centre is currently being redesignated as a WHO Collaborating Centre for Emerging and Zoonotic Diseases Detection, Diagnosis, Reference and Research. Institute Director – Dr Frank Plummer Head of Collaborating Centre – Dr Harvey Artsob The Collaborating Centre is housed within the Division of Zoonotic Diseases and Special Pathogens which currently has 31 indeterminate staff including 9 professionals. In addition there are 7 casuals, 5 post docs, 12 students and 2 visiting scientists (June 1, 2008). Collaborating Centre Head Harvey Artsob Mike -
Dr. Victor Dzau – President of the National Academy of Medicine (Music) Mark Masselli: This Is Conversations on Health Care
Dr. Victor Dzau – President of the National Academy of Medicine (Music) Mark Masselli: This is Conversations on Health Care. I am Mark Masselli. Margaret Flinter: And I am Margaret Flinter. Mark Masselli: Well Margaret, It’s the senate’s turn now the leadership in the senate is working to create their own version of a bill to replace Obamacare. A team of 13 republic and senators are attempting to rewrite a bill that dovetails off of the American Healthcare Act which passed in the house by a very slim margin before the congressional budget office had a chance to rate the bill and there is the rub Margaret. Margaret Flinter: Well the CPO report which came out after the house approved the health reform measure predicted that the ACHA would lead to 23 million Americans losing health insurance coverage and that the ACHA would significantly increase premiums for older and sicker Americans. Mark Masselli: Senate majority leader Mitch McConnell has already hinted that there may not be a bill that could win the support of 50 GOP senators at the moment. There were senators in the GOP like Senator Susan Collins of Maine, and Senator Lisa Murkowski of Alaska who say they will not support a bill that eliminates coverage for so many Americans. The process is being carried out in relative secrecy. Margaret Flinter: Well Mark what we do know in the President’s Budget is that it signals significant cuts across the healthcare spectrum. In addition to the $800 billion being cut from Medicaid by the GOP health reform measure, President Trump has proposed a significant cut to Medicaid on top of that which could lead to an estimated $1.7 trillion reduction in funding over 10 years that is just a devastating blow to healthcare for tens of millions of Americans. -
The Challenge of Reforming the US Health Care System
Wanting It All: The Challenge of Reforming the U.S. Health Care System Wanting It All: The Challenge of Reforming the U.S. Health Care System ©2007 Federal Reserve Bank of Boston. All rights reserved. edited by No part of this book may be reproduced in any form by any electronic or mechanical means (including photocopying, recording, or information storage and retrieval) without permission in writing from the publisher. Jane Sneddon Little This edited volume is based on a conference held in June 2005 by the Federal Reserve Bank of Boston. Conference Series No. 50 Cover illustrations by Art Glazer. This book was set in Sabon by Sztrecska Publishing and was printed and bound in the United States of America. Federal Reserve Bank of Boston Boston, Massachusetts vi Contents Comments on Enthoven’s “The U.S. Experience 119 Contents with Managed Care and Managed Competition” Michael E. Chernew Comments on Enthoven’s “The U.S. Experience 127 with Managed Care and Managed Competition” Sherry A. M. Glied 5 How the U.S. Health Care System Affects U.S. Labor 135 Markets The U.S. Health Care System and Labor Markets 137 Brigitte C. Madrian Acknowledgments ix Comments on Madrian’s “The U.S. Health Care System 165 1 Introduction 1 and Labor Markets” Reforming the U.S. Health Care System: Where There’s 3 Henry S. Farber a Will, There Could be a Way Employer-Funded Health Care and Labor Markets: 173 Jane Sneddon Little and Teresa Foy Romano An Insider’s View 2 Understanding the Political Challenge 27 Robert S. -
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BRINGING RESEARCH CLOSER TO HOME THE RESEARCHMARCH 2014 ADVOCATE Congress has begun Wolf, Fattah Named 2014 deliberations on funding levels for FY15. Pressure Whitehead Award Winners to cut federal spending Reps. Frank Wolf (R-VA) and Chaka Fattah (D-PA) will receive the 2014 Edwin this midterm election C. Whitehead Award for Medical Research Advocacy at this year’s Advocacy Awards dinner on March 12. year is enormous, and “Representatives Wolf and Fattah are exceptional champions for research,” said Re- we need advocates search!America Chair John Edward Porter. ”They have worked vigorously to in- to reach out to their crease funding for research, support policies that ignite public and private sector innovation, maintain our global competitiveness, and help patients and their fami- representatives. Rep. Frank Wolf Rep. Chaka lies struggling with costly and debilitating diseases.” (R-VA) Fattah (D-PA) Learn more on Both serve as their party’s leaders on the House Appropriations Committee’s Com- page 8. merce, Justice, Science Subcommittee. Wolf was a founder of the “Rising Above the Gathering Storm” Commission which sparked a national effort to bolster federal science, technology, engineering and mathematics (STEM) education and R&D programs. These efforts culmi- nated in the enactment of the first America COMPETES Act in 2007 to increase public-private partnerships and provide assistance to innovators throughout the country. Wolf also supported the act’s reauthorization in 2010. He is an active member of several caucuses, including research and development, Parkinson’s, Alzheimer’s and multi- ple sclerosis. “It has been a true privilege to play a role in advocating for the resources and policy environment required not only to maintain our global leadership in the scientific arena, but to optimize the use of science for the good of our nation and ACTION the world,” Wolf said. -
New & Classic Titles by Prof Victor Fuchs
New & Classic Titles by Prof Victor Fuchs & Important Titles on Health Economics Victor R Fuchs is the Henry J Kaiser Professor Emeritus at Stanford University where he applies economic analyses to social problems of national concern, with special emphasis on health and medical care. He is the author of nine books and editor of six others, including the classic Who Shall Live? Health, Economics, and Social Choice, second expanded edition published by World Scientific Publishing Co. Professor Fuchs’ contributions have been recognized by his election as president of the American Economic Association, election to the American Philosophical Society, the American Academy of Arts and Sciences, and the National Academy of Medicine. The award of the American Society of Health Economist for Lifetime Contributions to Health Economics is named in honor of Professor Fuchs. NEW Book by Prof Victor R Fuchs Health Economics and Policy Selected Writings by Victor Fuchs by Victor R Fuchs (Stanford) “The collection represents an extraordinary intellectual achievement and ... a handbook for anyone thinking about health and health policy.” Foreword by Sir Angus Deaton winner of the Nobel Prize in Economics “Victor Fuchs ... is one of the world’s most influential figures in health, medicine, and policy ... His writings could be considered the single most authoritative guidebook on health economics.” Foreword by Victor J Dzau MD, President of the National Academy of Medicine “You have to be as old as I am to know how long Victor Fuchs has been the dean of health economics. No one knows more, or has thought as carefully about all matters relating to health care than Victor.