HIST2H2AC Antibody Cat

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HIST2H2AC Antibody Cat. No.: 60-780 HIST2H2AC Antibody Specifications HOST SPECIES: Rabbit SPECIES REACTIVITY: Human Predicted species reactivity based on immunogen sequence: Rat, Bovine, Xenopus, HOMOLOGY: Mouse, Chicken, Monkey, Zebrafish, D This HIST2H2AC antibody is generated from rabbits immunized with a KLH conjugated IMMUNOGEN: synthetic peptide between 18-46 amino acids from the Central region of human HIST2H2AC. TESTED APPLICATIONS: WB APPLICATIONS: For WB starting dilution is: 1:1000 PREDICTED MOLECULAR 14 kDa WEIGHT: Properties This antibody is purified through a protein A column, followed by peptide affinity PURIFICATION: purification. CLONALITY: Polyclonal ISOTYPE: Rabbit Ig September 30, 2021 1 https://www.prosci-inc.com/hist2h2ac-antibody-60-780.html CONJUGATE: Unconjugated PHYSICAL STATE: Liquid BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide. CONCENTRATION: batch dependent Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. Additional Info OFFICIAL SYMBOL: HIST2H2AC ALTERNATE NAMES: Histone H2A type 2-C, Histone H2A-GL101, Histone H2A/q, HIST2H2AC, H2AFQ ACCESSION NO.: Q16777 PROTEIN GI NO.: 47117890 GENE ID: 8338 USER NOTE: Optimal dilutions for each application to be determined by the researcher. Background and References Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is BACKGROUND: wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. REFERENCES: 1) Ishibashi, T., et al. Biochemistry 48(22):5007-5017(2009) 2) Karaczyn, A.A., et al. Ann. Clin. Lab. Sci. 39(3):251-262(2009) 3) Pinato, S., et al. BMC Mol. Biol. 10, 55 (2009) : 4) Guerrero-Santoro, J., et al. Cancer Res. 68(13):5014-5022(2008) ANTIBODIES FOR RESEARCH USE ONLY. For additional information, visit ProSci's Terms & Conditions Page. September 30, 2021 2 https://www.prosci-inc.com/hist2h2ac-antibody-60-780.html.

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Supplementary materials Supplementary Table S1: MGNC compound library Ingredien Molecule Caco- Mol ID MW AlogP OB (%) BBB DL FASA- HL t Name Name 2 shengdi MOL012254 campesterol 400.8 7.63 37.58 1.34 0.98 0.7 0.21 20.2 shengdi MOL000519 coniferin 314.4 3.16 31.11 0.42 -0.2 0.3 0.27 74.6 beta- shengdi MOL000359 414.8 8.08 36.91 1.32 0.99 0.8 0.23 20.2 sitosterol pachymic shengdi MOL000289 528.9 6.54 33.63 0.1 -0.6 0.8 0 9.27 acid Poricoic acid shengdi MOL000291 484.7 5.64 30.52 -0.08 -0.9 0.8 0 8.67 B Chrysanthem shengdi MOL004492 585 8.24 38.72 0.51 -1 0.6 0.3 17.5 axanthin 20- shengdi MOL011455 Hexadecano 418.6 1.91 32.7 -0.24 -0.4 0.7 0.29 104 ylingenol huanglian MOL001454 berberine 336.4 3.45 36.86 1.24 0.57 0.8 0.19 6.57 huanglian MOL013352 Obacunone 454.6 2.68 43.29 0.01 -0.4 0.8 0.31 -13 huanglian MOL002894 berberrubine 322.4 3.2 35.74 1.07 0.17 0.7 0.24 6.46 huanglian MOL002897 epiberberine 336.4 3.45 43.09 1.17 0.4 0.8 0.19 6.1 huanglian MOL002903 (R)-Canadine 339.4 3.4 55.37 1.04 0.57 0.8 0.2 6.41 huanglian MOL002904 Berlambine 351.4 2.49 36.68 0.97 0.17 0.8 0.28 7.33 Corchorosid huanglian MOL002907 404.6 1.34 105 -0.91 -1.3 0.8 0.29 6.68 e A_qt Magnogrand huanglian MOL000622 266.4 1.18 63.71 0.02 -0.2 0.2 0.3 3.17 iolide huanglian MOL000762 Palmidin A 510.5 4.52 35.36 -0.38 -1.5 0.7 0.39 33.2 huanglian MOL000785 palmatine 352.4 3.65 64.6 1.33 0.37 0.7 0.13 2.25 huanglian MOL000098 quercetin 302.3 1.5 46.43 0.05 -0.8 0.3 0.38 14.4 huanglian MOL001458 coptisine 320.3 3.25 30.67 1.21 0.32 0.9 0.26 9.33 huanglian MOL002668 Worenine
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BMC Genetics Biomed Central
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Springer - Publisher Connector BMC Genetics BioMed Central Research article Open Access A novel replication-independent histone H2a gene in mouse Hiromi Nishida*, Takahiro Suzuki, Yasuhiro Tomaru and Yoshihide Hayashizaki Address: Laboratory for Genome Exploration Research Group, RIKEN Genomic Sciences Center (GSC), RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan Email: Hiromi Nishida* - [email protected]; Takahiro Suzuki - [email protected]; Yasuhiro Tomaru - [email protected]; Yoshihide Hayashizaki - [email protected] * Corresponding author Published: 19 February 2005 Received: 07 October 2004 Accepted: 19 February 2005 BMC Genetics 2005, 6:10 doi:10.1186/1471-2156-6-10 This article is available from: http://www.biomedcentral.com/1471-2156/6/10 © 2005 Nishida et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: An uncharacterized histone H2a-coding transcript (E130307C13) has been cloned from a mouse full-length cDNA library. This transcript is encoded on chromosome 6, approximately 4 kb upstream of a histone H4 gene, Hist4h4. The proteins encoded by this transcript and the human H2afj mRNA isoform-2 have the highest amino acid similarity. In this paper, we characterize it from the expression pattern given by quantitative RT-PCR. Results: Quantitative RT-PCR indicated that the gene that encodes E130307C13 (E130307C13) is regulated in a replication-independent manner, and therefore it is H2afj.
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bioRxiv preprint doi: https://doi.org/10.1101/2021.07.16.452616; this version posted July 16, 2021. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY 4.0 International license. 1 Tau modulates mRNA transcription, alternative 2 polyadenylation profiles of hnRNPs, chromatin remodeling 3 and spliceosome complexes 4 5 Montalbano Mauro1,2, Elizabeth Jaworski3, Stephanie Garcia1,2, Anna Ellsworth1,2, 6 Salome McAllen1,2, Andrew Routh3,4 and Rakez Kayed1,2†. 7 8 1 Mitchell Center for Neurodegenerative Diseases, University of Texas Medical Branch, Galveston, Texas, 9 77555, USA 10 2 Departments of Neurology, Neuroscience and Cell Biology, University of Texas Medical Branch, 11 Galveston, Texas, 77555, USA 12 3 Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas 13 77555, USA 14 4Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, 15 Galveston, TX, USA 16 † To whom correspondence should be addressed 17 18 Corresponding Author 19 Rakez Kayed, PhD 20 University of Texas Medical Branch 21 Medical Research Building Room 10.138C 22 301 University Blvd 23 Galveston, TX 77555-1045 24 Phone: 409.772.0138 25 Fax: 409.747.0015 26 e-mail: [email protected] 27 28 Running Title: Tau modulates transcription and alternative polyadenilation processes 29 30 Keywords: Tau, Transcriptomic, Alternative Polyadenilation,
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