HIST2H2AC Antibody Cat. No.: 60-780 HIST2H2AC Antibody Specifications HOST SPECIES: Rabbit SPECIES REACTIVITY: Human Predicted species reactivity based on immunogen sequence: Rat, Bovine, Xenopus, HOMOLOGY: Mouse, Chicken, Monkey, Zebrafish, D This HIST2H2AC antibody is generated from rabbits immunized with a KLH conjugated IMMUNOGEN: synthetic peptide between 18-46 amino acids from the Central region of human HIST2H2AC. TESTED APPLICATIONS: WB APPLICATIONS: For WB starting dilution is: 1:1000 PREDICTED MOLECULAR 14 kDa WEIGHT: Properties This antibody is purified through a protein A column, followed by peptide affinity PURIFICATION: purification. CLONALITY: Polyclonal ISOTYPE: Rabbit Ig September 30, 2021 1 https://www.prosci-inc.com/hist2h2ac-antibody-60-780.html CONJUGATE: Unconjugated PHYSICAL STATE: Liquid BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide. CONCENTRATION: batch dependent Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. Additional Info OFFICIAL SYMBOL: HIST2H2AC ALTERNATE NAMES: Histone H2A type 2-C, Histone H2A-GL101, Histone H2A/q, HIST2H2AC, H2AFQ ACCESSION NO.: Q16777 PROTEIN GI NO.: 47117890 GENE ID: 8338 USER NOTE: Optimal dilutions for each application to be determined by the researcher. Background and References Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is BACKGROUND: wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. REFERENCES: 1) Ishibashi, T., et al. Biochemistry 48(22):5007-5017(2009) 2) Karaczyn, A.A., et al. Ann. Clin. Lab. Sci. 39(3):251-262(2009) 3) Pinato, S., et al. BMC Mol. Biol. 10, 55 (2009) : 4) Guerrero-Santoro, J., et al. Cancer Res. 68(13):5014-5022(2008) ANTIBODIES FOR RESEARCH USE ONLY. For additional information, visit ProSci's Terms & Conditions Page. September 30, 2021 2 https://www.prosci-inc.com/hist2h2ac-antibody-60-780.html.