CNKSR2 (NM 001168649) Human Tagged ORF Clone Product Data

OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for RC230540

CNKSR2 (NM_001168649) Human Tagged ORF Clone Product data:

Product Type: Expression Plasmids Product Name: CNKSR2 (NM_001168649) Human Tagged ORF Clone Tag: Myc-DDK Symbol: CNKSR2 Synonyms: CNK2; KSR2; MAGUIN; MRXSHG Vector: pCMV6-Entry (PS100001) E. coli Selection: Kanamycin (25 ug/mL) Cell Selection: Neomycin

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. View online » ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 1 / 5 CNKSR2 (NM_001168649) Human Tagged ORF Clone – RC230540

ORF Nucleotide >RC230540 representing NM_001168649 Sequence: Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC

ATGGCTCTGATAATGGAACCGGTGAGCAAATGGTCTCCGAGTCAAGTAGTGGACTGGATGAAAGGTCTTG ATGACTGTTTGCAGCAGTATATTAAGAACTTTGAGAGGGAGAAGATCAGTGGGGACCAGCTGCTGCGCAT TACACATCAGGAGCTAGAAGATCTGGGGGTCAGCCGCATTGGCCATCAGGAACTGATCTTGGAAGCAGTT GACCTTCTGTGTGCATTGAATTATGGCTTGGAAACAGAAAATCTAAAAACCCTTTCTCACAAGTTGAATG CATCTGCCAAAAATCTGCAGAATTTTATAACAGGAAGGAGAAGGAGTGGCCATTATGATGGGAGGACCAG CCGAAAATTGCCAAACGACTTTCTGACCTCAGTTGTGGATCTGATTGGAGCAGCCAAGAGTCTGCTTGCC TGGTTGGACAGGTCACCATTTGCTGCTGTGACAGACTATTCAGTTACAAGAAATAATGTCATACAACTCT GCCTGGAGTTAACAACAATTGTGCAACAGGATTGTACTGTATATGAAACAGAGAATAAAATTCTTCACGT GTGTAAAACTCTTTCTGGAGTCTGTGACCACATCATATCCCTGTCGTCAGATCCTCTGGTTTCACAGTCT GCTCACCTGGAAGTGATTCAACTGGCAAACATTAAACCAAGCGAAGGGCTGGGTATGTATATTAAATCTA CATATGATGGCCTCCATGTAATTACTGGAACCACAGAAAATTCACCTGCAGATCGGTGCAAGAAAATCCA TGCTGGCGATGAAGTGATTCAAGTTAATCATCAGACTGTGCCTCTTATACCTAGAAGTCCCACAAGCAGC GTTGCCACGCCTTCCAGCACCATCAGTACACCCACCAAAAGAGACAGTTCTGCCCTCCAGGATCTCTACA TTCCCCCTCCTCCTGCAGAACCATATATTCCCAGGGATGAAAAAGGAAACCTTCCTTGTGAAGACCTCAG AGGACATATGGTGGGCAAGCCAGTGCATAAGGGATCTGAATCACCAAATTCATTTCTGGATCAGGAATAT CGAAAGAGATTTAATATTGTCGAAGAAGATACTGTCTTATATTGCTATGAATATGAAAAAGGAAGATCAA GTAGTCAAGGAAGACGAGAAAGCACCCCAACTTATGGCAAGCTACGACCTATATCTATGCCAGTGGAATA TAATTGGGTGGGGGACTATGAAGATCCAAATAAGATGAAGAGAGATAGTAGAAGAGAAAACTCTCTACTT CGGTATATGAGCAATGAAAAGATTGCTCAAGAAGAATACATGTTTCAGAGAAACAGCAAAAAGGACACAG GGAAGAAGTCAAAAAAGAAGGGTGATAAGAGTAATAGCCCAACTCACTATTCATTGCTACCTAGTTTACA AATGGATGCACTGAGACAAGACATCATGGGCACTCCTGTGCCAGAGACCACACTATACCATACATTTCAG CAGTCCTCACTGCAGCACAAATCAAAGAAGAAAAACAAAGGTCCTATAGCAGGCAAGAGCAAAAGACGAA TTTCTTGCAAAGATCTTGGCCGTGGTGACTGTGAGGGCTGGCTTTGGAAAAAGAAAGATGCGAAGAGTTA CTTTTCACAGAAATGGAAAAAATATTGGTTTGTCCTAAAGGATGCATCCCTTTATTGGTATATTAATGAG GAGGATGAAAAAGCAGAAGGATTCATTAGCCTGCCTGAATTTAAAATTGATAGAGCCAGTGAATGCCGCA AAAAATATGCATTCAAAGCCTGTCATCCTAAAATCAAAAGCTTTTATTTTGCTGCTGAACATCTTGATGA TATGAACAGGTGGCTTAACAGAATTAATATGCTGACTGCAGGATATGCAGAAAGAGAGAGGATTAAGCAG GAACAAGATTACTGGAGTGAGAGTGACAAGGAAGAAGCAGATACTCCATCAACACCAAAACAAGATAGCC CTCCACCCCCATATGATACATACCCACGACCTCCCTCGATGAGTTGCGCCAGTCCTTATGTGGAAGCAAA ACATAGCCGACTTTCCTCCACGGAGACTTCTCAGTCTCAGTCTTCTCATGAGGAGTTTCGCCAGGAAGTA ACTGGGAGCAGTGCAGTGTCTCCCATTCGCAAGACAGCCAGTCAGCGCCGCTCCTGGCAGGATTTAATTG AGACGCCACTGACAAGTTCAGGCTTACACTATCTTCAGACTCTGCCCCTGGAGGATTCTGTCTTCTCTGA CTCCGCGGCCATCTCCCCAGAGCACAGGCGGCAGTCTACCCTGCCAACTCAGAAATGCCACCTGCAGGAT CACTATGGGCCATACCCCTTAGCTGAGAGTGAGAGGATGCAAGTGCTAAATGGAAATGGGGGCAAGCCTC GAAGTTTTACTCTGCCTCGAGATAGCGGGTTCAACCATTGCTGTCTGAATGCTCCAGTTAGTGCCTGTGA CCCACAGGATGACGTGCAACCCCCAGAGGTGGAGGAAGAGGAGGAGGAGGAGGAGGAGGAAGGGGAGGCA GCAGGGGAAAACATAGGAGAAAAAAGC

ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 2 / 5 CNKSR2 (NM_001168649) Human Tagged ORF Clone – RC230540

Protein Sequence: >RC230540 representing NM_001168649 Red=Cloning site Green=Tags(s)

MALIMEPVSKWSPSQVVDWMKGLDDCLQQYIKNFEREKISGDQLLRITHQELEDLGVSRIGHQELILEAV DLLCALNYGLETENLKTLSHKLNASAKNLQNFITGRRRSGHYDGRTSRKLPNDFLTSVVDLIGAAKSLLA WLDRSPFAAVTDYSVTRNNVIQLCLELTTIVQQDCTVYETENKILHVCKTLSGVCDHIISLSSDPLVSQS AHLEVIQLANIKPSEGLGMYIKSTYDGLHVITGTTENSPADRCKKIHAGDEVIQVNHQTVPLIPRSPTSS VATPSSTISTPTKRDSSALQDLYIPPPPAEPYIPRDEKGNLPCEDLRGHMVGKPVHKGSESPNSFLDQEY RKRFNIVEEDTVLYCYEYEKGRSSSQGRRESTPTYGKLRPISMPVEYNWVGDYEDPNKMKRDSRRENSLL RYMSNEKIAQEEYMFQRNSKKDTGKKSKKKGDKSNSPTHYSLLPSLQMDALRQDIMGTPVPETTLYHTFQ QSSLQHKSKKKNKGPIAGKSKRRISCKDLGRGDCEGWLWKKKDAKSYFSQKWKKYWFVLKDASLYWYINE EDEKAEGFISLPEFKIDRASECRKKYAFKACHPKIKSFYFAAEHLDDMNRWLNRINMLTAGYAERERIKQ EQDYWSESDKEEADTPSTPKQDSPPPPYDTYPRPPSMSCASPYVEAKHSRLSSTETSQSQSSHEEFRQEV TGSSAVSPIRKTASQRRSWQDLIETPLTSSGLHYLQTLPLEDSVFSDSAAISPEHRRQSTLPTQKCHLQD HYGPYPLAESERMQVLNGNGGKPRSFTLPRDSGFNHCCLNAPVSACDPQDDVQPPEVEEEEEEEEEEGEA AGENIGEKS

TRTRPLEQKLISEEDLAANDILDYKDDDDKV Restriction Sites: SgfI-MluI

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 3 / 5 CNKSR2 (NM_001168649) Human Tagged ORF Clone – RC230540

Cloning Scheme:

Plasmid Map:

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 4 / 5 CNKSR2 (NM_001168649) Human Tagged ORF Clone – RC230540

ACCN: NM_001168649 ORF Size: 2547 bp OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. RefSeq: NM_001168649.3 RefSeq ORF: 2550 bp Locus ID: 22866 UniProt ID: Q8WXI2, B3KPN2 MW: 96.8 kDa Gene Summary: This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]