Catalog for Cosmetic Ingredients 5 Ultrafine Zinc Oxide / Microfine Titanium Dioxide Dispersions Example Non-Chemical Sunscreen Formulations

CATA LOG for cosmetic ingredients

The Gentle Communication Between People and Chemistry Sakai Chemical Industry Co.,Ltd.

Sakai Chemical Industry Co., Ltd.

［Tokyo］TEL +81-3-5823-3726 FAX +81-3-3861-1511 ［Osaka］TEL +81-72-223-4155 FAX +81-72-223-4177 URL http://www.sakai-chem.co.jp Contact E-mail [email protected]

Issued date：April 1, 2019 Our company launched its business with the manufacture of zinc oxide in 1918. th 1ANNIVERSARY00 2020 おかげさまで 100周年 At that time, zinc oxide was employed as a base material for face powders for women and actors. Today, in addition to its use in cosmetics 2018 and sunscreens, zinc oxide is used in a wide range of applications, including electronic materials, rubber products, and paints. In addition to zinc oxide products, Sakai Chemical Industry manufactures a wide variety of characteristic cosmetic ingredients, including titanium dioxide, flake-shaped barium sulfate, and spherical calcium carbonate. Cosmetic products such as foundations and sunscreens are required to be both extremely delicate and to fulfill specific functions. Requirements for these products include a smooth and moist texture, a natural-looking finish, and the outstanding ability to screen UV rays.

Sakai Chemical Industry contributes to the realization of beautiful and healthy skin through our P.6-7 2010 Ref. P.9 unique particle size, particle shape control, and surface treatment technologies. Ref.

P.4 Ref.

Spherical zinc oxide formed by ﬂake-shaped particles CANDY ZINC Ultraﬁne zinc oxide dispersion DIF Series

Microﬁne titanium P.11 P.11 P.13 P.5 dioxide dispersion 2000 Ultraﬁne zinc oxide Ref. Ref. Ref. Ref. DIS Series FINEX Series

Spherical calcium Pigment-grade titanium Inorganic ﬂuorescent Microﬁne titanium carbonate Calmaru dioxide MKR Series materials for cosmetics 1918 Began manufacturing dioxide STR Series Lumate Series zinc oxide for face powder P.10 P.8 1990 Ref. Ref. Suncare & Skincare Material 1918

Makeup Material Flake-shaped barium Hexagonal ﬂake-shaped sulfate H Series zinc oxide XZ Series

2 Sakai Chemical Industry Sakai Chemical Industry 3 Ultrafine Zinc Oxide FINEX Series Microfine Titanium Dioxide STR Series

Ultrafine zinc oxide FINEX Series〈Powder〉 Microfine titanium dioxide STR Series〈Powder〉 Efficient shielding of UVA rays while keeping high transparency. High transparency and efficient UVB shielding; surface activity is controlled by dense surface coating.

Grade List Grade List

Primary Composition (%) Primary Composition(%) Quasi- Quasi- Characteristics Grade INCI name Characteristics Grade INCI name particle size Hydrated Hydrogen particle size Titanium Aluminum Hydrated Hydrogen Zinc oxide Triethoxycaprylylsilane drug Triethoxycaprylylsilane drug (nm) silica dimethicone (nm) dioxide hydroxide silica dimethicone FINEX-50 20 100 STR-100N 15 100 －－－ Yes Non-coated grade Titanium dioxide －－－－Yes Non-coated grade FINEX-30 35 Zinc oxide 100 －－－ Yes in Titanium dioxide （ EU ） Hydrated silica FINEX-25 60 100 －－－ STR-100A-LP 15 84 4 8 4 － Yes Aluminum hydroxide Zinc oxide Standard NANOFINE-50LP 20 96 － 4 － Yes Hydrogen dimethicone Hydrogen dimethicone Standard grade Titanium dioxide Zinc oxide STR-100C-LP 15Aluminum hydroxide 89 7－ 4 － Yes FINEX-33W 35 95 5 －－ Yes Hydrated silica Hydrogen dimethicone Passivated grade FINEX-52W-LP2 20 Zinc oxide 86 10 4 － Titanium dioxide Hydrated silica Yes STR-100W-LP 15Hydrated silica 75－ 17 8 － Yes FINEX-33W-LP2 35 Hydrogen dimethicone 91 5 4 － Hydrogen dimethicone Titanium dioxide High-transparency grade FINEX-50S-LP2 20 96 － 4 － Fatty acid-treated Zinc oxide STR-100C-LF 15Aluminum hydroxide 84 9 －－－ Yes FINEX-30S-LPT 35 96 － 4 － Yes grade Low-viscosity grade Hydrogen dimethicone Stearic acid （7% Stearic acid） FINEX-25-LPT 60 97 － 3 － Titanium dioxide No Texture-modiﬁed Zinc oxide STR-100W-OTS 15Hydrated silica 73 － 18－ 9 No Texture-modiﬁed grade FINEX-50-OTS 20 93 －－ 7 Yes in grade Triethoxycaprylylsilane （ EU ） Triethoxycaprylylsilane Hydrophilic Titanium dioxide STR-100W(G) 15 80－ 20 －－Yes passivated grade Hydrated silica UVA and UVB Titanium dioxide Optical characteristics of FINEX Series STR-40-OTS 35 95 －－－ 5 No shielding grade Triethoxycaprylylsilane ■Total light transmittance ■Parallel light transmittance

100 100 Electron microscope image and optical characteristics of STR series

80 80

）） ■STR-100A-LP TEM image ■Optical characteristics of STR series ％％

60 100 （（ 60 20nm（FINEX-50） 20nm（FINEX-50）

40 40 80

35nm（FINEX-30） 35nm（FINEX-30） High-dense silica ） Transmittance Transmittance 60nm（FINEX-25） 60nm（FINEX-25） Aluminum hydroxide ％

20 20 60 280nm（Fine zinc oxide） 280nm（Fine zinc oxide）（

0 0 40 300 400 500 600 700 800 400 500 600 700 800 15nm（STR-100N）

Wavelength(nm) Wavelength(nm) Titanium dioxide Transmittance 20 35nm（STR-40N） 200nm（MKR-1）

Characteristics vary based on the particle size. FINEX-25 has high UVA shielding performance, and FINEX-50 has high transparency. 0 5 nm 300 400 500 600 700 Wavelength(nm) Titanium dioxide is densely coated. High-density silica coating (passivated grade) STR-40 type has high UVA shielding performance, and STR-100 type has high transparency. ■FINEX-52W-LP2 TEM image ■Image of high density ■Difference in activity due to silica coating (Vaseline discoloration)

silica coating A PWC 10% Vaseline paste was prepared, subjected to UV irradiation for 96 hours, and tested for discoloration. 30 Untreated zinc oxide (silica, silicone content 0%) Photochromism of titanium dioxide High-density silica layer 25 Silicone-treated zinc oxide (silica content 0%) Silica + siliconized zinc oxide (silica content 10%) Zinc oxide Silica + siliconized zinc oxide (silica content 15%) 20 Silica + siliconized zinc oxide (silica content 20%) Photochromism is a phenomenon in which exposure to High-dense silica light causes a color change in titanium dioxide.

E 15 ⊿ After exposure 10 Test method STR's dense surface coating 5 Samples with different W/O realizes greater control in formulations were exposed to photocatalytic activity in Zinc oxide is densely coated by a silica layer. 0 Hydrogen dimethicone layer 0 10 20 30 40 50 60 70 80 90 100 sunlight for four hours and titanium dioxide than that UV irradiation time (hr) observed for color changes. STR- of the competitors' products. Competitor A Competitor B We can control photocatalytic activity of zinc 100A-LP STR- Competitor A Competitor B oxide by coating with high density silica. 100A-LP

4 Sakai Chemical Industry catalog for cosmetic ingredients 5 Ultrafine Zinc Oxide / Microfine Titanium Dioxide Dispersions Example Non-chemical Sunscreen Formulations

■O/W type gel cream ■W/O milk Characteristics・Including the aqueous dispersion AB series, which uses hydrophobic powder, Characteristics・Achieves high transparency and high UV shielding non-chemically. in the water phase achieves high UV shielding in a non-chemical O/W formulation. ・Including D5 dispersions allows for non-sticky, refreshing skin feel. Ultraﬁne Zinc Oxide Dispersion DIF Series ・Increased SPF and water resistance and improved friction compared to the conventional silica-coated powder formulation. [wt%] ※（）Powder concentration [wt%] Grade List Composition / Formulation No. SSS007 SSS011 SSS099 Composition / Formulation No. SSS088 SSS098 1 Propylene glycol dicaprate 6.5 10.0 10.0 1 DIF-AW4 38.0 (19) － Dispersoid Composition 2 Hydrogenated polyisobutene 11.5 12.0 9.0 2 DIF-5CS － 20.0 (10) Dispersion （Powder） Quasi- 3Dimethicone 1.5 1.5 1.5 3DIS-11A 24.0 (9.6) 24.0 (9.6) Characteristics Dispersion medium Primary ZnO surface treatment grade name particle size drug 40.7Behenyl alcohol 0.7 0.7 4Neopentylene glycol dicaprate 6.0 6.0 composition Powder grade content Hydrated Hydrogen nm Triethoxycaprylylsilane （wt%）（）（%） silica dimethicone 5 Sorbitan sesquistearate 0.5 0.5 0.5 5 Cyclopentasiloxane 3.5 12.3 Zinc oxide Water dispersions 6 Glyceryl stearate 0.3 0.3 0.3 6 Dimethicone 4.0 4.0 7 Sulfonic acid polymer 0.6 0.4 0.5 7 PEG-9 Polydimethylsiloxyethyl dimethicone 1.5 1.5 DIF-AB-33W 60 FINEX-33W-LP2 5535 ◯◯ － Yes 8 Polysorbate 60 1.0 1.0 1.0 8 Cyclopentasiloxane, Dimethicone crosspolymer 1.0 1.0 High transparency Water Bentonite9 0.1 0.1 0.1 9 Polymethylsilsesquioxane 0.5 0.5 Good skin feel DIF-AB-3CS No 60 FINEX-30-OTS 5835 －－ ◯ Yes in 10 Crystalline cellulose（2%） 2.5 2.5 2.5 10 Sodium citrate 0.2 0.2 (Prototype) （ EU ） 11 1,3-butylene glycol 6.0 4.0 6.0 11 Sodium chloride 0.5 0.5 Zinc oxide D5 dispersions water12 48.8 22.0 42.9 12 1,3-butylene glycol 3.0 5.0 13 DIS-AB-10W 20.0（10）※ 20.0 (10) － water13 17.8 25.0 Standard DIF-3ST2 50 FINEX-30S-LPT 4835 －◯ － Yes 14DIF-AB-33W － 25.0 (15) － High transparency 15 DIF-AB-3CS －－25.0 (15) vivo SPF（n=2） 59.4 53.0 DIF-AW4 50 FINEX-52W-LP2 4320 ◯◯ － Yes High passivity vivo UVAPF（n=2） 19.2 16.0 Cyclopentasiloxane vivo SPF（n=2） 47.8 56.0 31.3 High UV shielding DIF-3W4 60 FINEX-33W-LP2 5435 ◯◯ － Yes vivo UVAPF（n=2） 16.9 19.2 20.0 ＜Creation procedure＞ High passivity A. Evenly mix ingredients 1 to 9. B. Evenly mix ingredients 10 to 13. No ＜Creation procedure＞ Good skin feel DIF-5CS 50 FINEX-50-OTS 4620 －－ ◯ Yes in C. Add B to A and emulsify. （ EU ） A. Evenly mix ingredients 1 to 6 and heat to 80°C. B. Evenly mix ingredients 7 to 12 and heat to 80°C. Zinc oxide Ester oil dispersions C. Add A to B and emulsify. D. Bring C to 60°C or less and then add 13 to 15 and mix evenly. DIF-OP-3W 70 Ethylhexyl palmitate FINEX-33W-LP2 6435 ◯◯ － Yes High passivity High concentration Comparison of sunlight resistance of inorganic and organic UV absorbers DIF-TL-3W 70 Isotridecyl isononanoate FINEX-33W-LP2 6435 ◯◯ － Yes ■FINEX-50S-LP2（ZnO） ■UVA organic UV absorber ※Packed in 20 kg plastic bottle (15 kg for DIF-AB-33W and DIF-AB-3CS) 100 100 0min 30min

0min 60min 120min ））

180min ％ 180min ％

（（ Microﬁne Titanium Dioxide Dispersion DIS, GT Series 50 50 Transmittance Transmittance high UV shielding effect high UV shielding effect

Grade List 0 0 300 320 340 360 380 400 300 320 340 360 380 400 Dispersoid Composition Wavelength(nm) Wavelength(nm) Dispersion （Powder） Quasi- Characteristics Dispersion medium Primary TiO2 surface treatment grade name particle size drug ■STR-100A-LP（TiO₂） ■UVB organic UV absorber composition Powder grade content Hydrated Aluminum Hydrogen （nm）（wt%）（%） silica hydroxide dimethicone 100 100

0min

Titanium dioxide Water dispersions ））

180min ％％

（ High SPF （ DIS-AB-10W 50 STR-100W-LP 3815 ◯ － ◯ Yes Good feel 50 50 Water

0min 30min Transmittance High passivity GT-10W2 40 STR-100W 3215 ◯ －－ Yes Transmittance high UV shielding effect high UV shielding effect 60min 120min 180min Titanium dioxide D5 dispersions 0 0 300 320 340 360 380 400 300 320 340 360 380 400 Standard DIS-11A40Cyclopentasiloxane STR-100A-LP 3415 ◯ ◯ ◯ Yes Wavelength(nm) Wavelength(nm) High transparency Titanium dioxide Ester oil dispersions Inorganic UV absorbers STR-100A-LP and FINEX-50S-LP2 DIS-OP-10A 50 Ethylhexyl palmitate STR-100A-LP 4215 ◯ ◯ ◯ Yes have better simulated sunlight resistance than organic UV absorbers. High passivity High concentration DIS-TL-10A 50 Isotridecyl isononanoate STR-100A-LP 4215 ◯ ◯ ◯ Yes Measurement method 1. FINEX-50S-LP2 and STR-100A-LP were both dispersed and applied to glass slides with a bar coater #6 (13.7 μm when wet). ※Packed in 20 kg plastic bottle (15 kg for DIS-AB-10W) 2. The total light transmittance of the coating ﬁlm before illumination (0 minutes) was measured with a spectrophotometer. 3. Artiﬁcial sunlight was illuminated with a weather meter (255W/m2) for 30, 60, 120, and 180 minutes, and the total light transmittance was measured for each.

6 Sakai Chemical Industry catalog for cosmetic ingredients 7 Special Shape Zinc Oxide Special Shape Zinc Oxide

Hexagonal Flake-shaped Zinc Oxide XZ Series Spherical Zinc Oxide Formed by Flake-shaped Particles CANDY ZINC

Grade List Grade List

Grade Particle size (nm) Thickness (nm) INCI name Characteristics Grade Particle size (nm) INCI name Characteristics

XZ-100F-LP 100 30 High UV shielding effect. Zinc oxide Has a good skin feel while also offering CANDY ZINC 1000 1000 Booster effect to increase SPF Polysorbate 80 high ultraviolet shielding and sebum absorption effect. XZ-300F-LP 300 100 Zinc oxide Can be also used as a white pigment. Hydrogen dimethicone Good skin feel and the ability to produce optimal whiteness XZ-1000F-LP 1000 290 enable it to be substituted for pigment-grade titanium dioxide. Pressure resistance test XZ-3000F-LP 3000 750 Best skin feel in the series. Zinc oxide Comfortable texture that blends with skin. XZ-1000F-KR 1000 290 CANDY ZINC particles keep their shape Before pressing 10MPa × 30sec 20MPa × 30sec Stealdimonium hydroxypropyl High near-infrared shielding effect. hydrolysed keratin even after pressing at 20 MPa. ※Non-coated items also included in lineup

XZ-100F XZ-300F XZ-1000F XZ-3000F Measurement conditions 2 g of test samples were placed in a 35 mm diameter ring and compacted.

100nm 100nm 1μm 1μm

XZ-100F-LP shows a high level of penetration, Level of penetration 1400 and also functions as a ﬁxation agent 1200 1000 for foundations. 800 600 Measurement conditions 400 Sebum absorption of CANDY ZINC

3 g of powder was placed in a 25-mm diameter ring and pressed at 30 MPa. high Solidiﬁcation intensity 200 Level of penetration (g/mm) Rheometer: 1 mm diameter, 1 mm penetration speed: 6 cm/min 0 XZ-100F-LP XZ-300F-LP XZ-1000F-LP Pigment-grade titanium dioxide Talc CANDY ZINC has a high sebum absorption effect.

Near-infrared rays shielding performance of hexagonal flake-shaped zinc oxide Test sample 300 Particle size（μm） Coating film transmittance CANDY ZINC 1000 1 The hexagonal flake-shaped zinc oxides XZ-1000F and XZ- 100 FINEX-50 0.02 250 Zinc oxide (JIS-1) 0.5~0.8 1000F-KR show high NIR shielding performance. 80 (mg/g)

Silicon powder 6~10 200 ）

％ Porous silica 2 Measurement conditions （ 60 150 Measured coating ﬁlm at 20 wt% pulled with 1.5 mil applicator 40 Mixing ratio of artiﬁcial sebum and 100 Transmittance XZ-100F XZ-300F XZ-1000F test samples 20 high NIR shielding performance high Sebum absorption effect

XZ-3000F XZ-1000F-KR Mixing ratio Sebum absorption rate 50

0 Test sample 5% 300 500 700 900 1100 1300 1500 1700 1900 2100 2300 2500 Oleic acid 5% 0 Wavelength(nm) Squalene 10% CANDY ZINC FINEX-50 Zinc oxide Silicon Porous 1000 (JIS-1) powder silica Olive oil 10%

Application of hexagonal ﬂake-shaped zinc oxide on the skin Artiﬁcial sebum Isopropyl alcohol 70%

The XZ series shows effective sunblock performance and Measurement method a good texture due to apply evenly on the skin. 1 Artiﬁcial sebum was mixed with test samples in centrifuge tubes, in the ratios shown above. 2 After being left to stand for 30 minutes, the mixtures were centrifugally separated, and the separated solvents were collected. Measurement conditions 3 The solvents were measured using FT-IR to enable calculation of the peak area of 2945-2875 cm-1 (C-H symmetric stretch vibration) derived from sebum. ①Sample was spread on the skin and transferred using carbon tape. 4 Calibration curves were formulated in order to calculate the sebum absorption rate. ②Transferred sample was observed using SEM.

XZ-1000F applied to the skin

8 Sakai Chemical Industry catalog for cosmetic ingredients 9 Flake-shaped Barium Sulfate H Series Spherical Calcium Carbonate Calmaru, Pigment-grade Titanium Dioxide MKR Series

Flake-shaped barium sulfate H Series Spherical Calcium Carbonate Calmaru

Grade List Grade List 10μm

Grade Particle size(μm) INCI name Characteristics Grade Particle size (μm) INCI name Characteristics

H7 Offers matte finish. Calcium carbonate SCS-M5 5 Offers both excellent soft focus effect and a high level of press moldability. HM 10 Good balance of matte and luster finish. Sodium metaphosphate Barium sulfate HL 15 Offers more luster than HM. HG 20 The grade with the most shiny luster finish. Drop test of molded compound Barium sulfate H-LFM 7 Matte finish with good smoothness. Magnesium myristate 15 By blending Calmaru and Flake-shaped barium Barium sulfate HG-LFP 20 Magnesium hydroxide Luster finish with good smoothness. sulfate H, press formability is improved. 10 Palmitic acid 5 Measurement conditions high Press formability

Samples (10 g) were placed in a vessel and molded by pressing at 2 MPa for 30 sec. Number of cycles to breakage 0 Talc/ Talc/ Talc/ SEM image Talc/H The molded compounds were dropped from a height of 10 cm, Composition Talc=100 Calmaru 5μm Nylon beads Acrylic beads =90/10 and the number of cycles until breakage was recorded. =90/10 =90/10 =90/10 H HM HL HG

Soft focus effect of Calmaru after sebum absorption

Even after moistening with sebum, Calmaru does Powder After sebum kneading Powder After sebum kneading The change in the soft focus not change color and keeps its soft focus effect. effect of the extender pigment

10μm 10μm 10μm 10μm was examined using oleic acid, Measurement conditions one of the major components Calmaru Barium sulfate Artificial sebum (0.9 g) was mixed with test materials (1.2 g), of sebum. Optical characteristics of flake-shaped barium sulfate and the powder was checked for color change. Powder After sebum kneading Powder After sebum kneading The artificial sebum was produced by mixing oleic acid, squalane, Talc, Mica, Sericite Flake-shaped barium sulfate Titanium dioxide and olive oil in a ratio of 1:2:2.

Unable to conceal skin Able to obscure skin blemishes Coats the skin too heavily and Refractive Refractive Refractive Sericite Nylon beads index blemishes due to lower index because refractive index is slightly index produces unnatural ﬁnish due 1.58 refractive index (1.58). 1.64 higher than that of bare skin. 2.67 to high refractive index. Pigment-grade Titanium Dioxide MKR Series

Grade List

melanin SKIN melanin SKIN melanin Grade Particle size (nm) INCI name Characteristics MKR-1 200 Hydrophilic. Aluminum-free. Can be used in water-based formulations. Titanium dioxide Hydrophobic. Aluminum-free. MKR-1S 200 Hydrogen dimethicone Reduced photocatalytic activity in comparison to competitors' products.

Comparative data of ﬂake-shaped barium sulfate and other materials Conforms to E171.

The soft focus effect of ﬂake-shaped barium 30 Vaseline Discoloration Test Flake-shaped barium sulfate 25 Mica sulfate is higher than with other materials. Sericite 20 Talc MKR Series shows reduced photocatalytic 10 Synthetic mica Measurement conditions 8 15 activity compared to standard products.

0.2 g of sample + 0.8 g of silicone (PWC = 20 wt%) were Haze value (%) 6 E Standard product

10 ⊿ dispersed twice with 25 turns at 100 pounds in a Hoover Measurement conditions 4 MKR-1 muller, applied to a glass plate with a 1 mil applicator, 5 Larger soft focus effect Vaseline pastes containing 10% powder were formulated. Discoloration 2 MKR-1S and measured in a haze meter. 0 L, a, and b values were measured following UV irradiation, and ⊿E was calculated. 0 0 20 40 60 80 100 24 48 72 96 120 Total light transmittance(%) 365nm UV irradiation time (hr)

10 Sakai Chemical Industry catalog for cosmetic ingredients 11 Introduction of performance of products for base. Inorganic Fluorescent Materials Lumate® Series

Comparison Data of Performance of Base Makeup Products Cosmetic Inorganic Fluorescent Materials Lumate® Series

Amount of oil absorbed by various powders ●Absorbs harmful UV rays, transforming them to visible light to shine. ●Composed of elements used in cosmetic materials. ■Flake-shaped powder ■Spherical powder Characteristics ●Green (Lumate® G) corrects reddish hues, red (Lumate® R) gives skin a healthy look, and blue (Lumate® B) gives it a translucent look. Measurement method H (7μm) Calmaru SCS-M5 (5μm) ●Various shining colors including white can be produced by combining the three Lumate products. HM (10μm) 0.5 g of a sample was measured out and CANCY ZINC (1μm) IPM was dripped onto it while mixing HL (15μm) Nonporous silica (5μm) the sample with a spatula to measure HG (20μm) the amount of oil absorbed. H-LFM (7μm) Porous silica (5μm) Change in powder color before and during UV irradiation HG-LFP (20μm) PMMA (5μm) Talc (7～11μm) Nylon beads (5μm) Mica (19μm) Lumate® G UV Sericite (10μm) Silicon powder (2～7μm) 0 102030405060 0 10203040506070 INCI name： Zinc oxide Oil absorption (ml/100g) Oil absorption (ml/100g) ■SEM image ■Emission / excitation spectra ■Particle size distribution 10 Emission spectra Improvement of long lasting effect by ﬂake-shaped barium sulfate/H-LFM Excitation spectra 8

Evaluation method 4 Frequency(%) After washing the face, lotion and milk were used to condition the skin and left to be absorbed by the skin for 15 minutes, following which a powder foundation was applied in appropriate 2 Relative emission intensity

amounts and the number of spots and pores was measured using a skin measurement device, VISIA. 1μm 0 350 400 450500 550 600 650 700 0.1 1 10 100 ■Pore Wavelength(nm) Particle size(μm)

Before makeup After makeup 2 hours later 120 Lumate® R UV 100 Mica 100 Mica H-LFM INCI name： Magnesiun / Manganese / Titanium Oxide 80 ％ ■SEM image ■Emission / excitation spectra ■Particle size distribution 60 62 14 45 Emission spectra 12

Pore score 44 40 Excitation spectra 40 10

High soft focus effect Keep!! 20 H-LFM 8 0 6

Before After 2 hours Frequency(%) 4 makeup makeup later

Relative emission intensity 2

1μm 0 350400 450 500 550 600 650 700 0.1 1 10 100 ■Spot Wavelength(nm) Particle size(μm)

Before makeup After makeup 2 hours later 120 Lumate® B Mica UV 100 100 Mica H-LFM INCI name： Calcium Cerium Phosphate 80 81 ％ 68 60 ■SEM image ■Emission / excitation spectra ■Particle size distribution 56 59 10

Spot score 40 Emission spectra Keep!! Excitation spectra 8

High soft focus effect 20 H-LFM 6 0 Before After 2 hours 4

makeup makeup later Frequency(%) 2 Relative emission intensity

1μm 0 Flake-shaped barium sulfate was conﬁrmed to have a soft focus effect higher than that of mica, and a long make-up effect. 300350 400 450 500 550 600 650 700 0.1 1 10 100 Wavelength(nm) Particle size(μm)

12 Sakai Chemical Industry catalog for cosmetic ingredients 13 Corporate proﬁle Network

Corporate proﬁle (As of October 1, 2018)

Company name Sakai Chemical Industry Co., Ltd. Head ofﬁce 5-2 Ebisujima-cho, Sakai-ku, Sakai, Osaka 590 -8502 JAPAN Tel +81-72-223-4111 Founded June 25, 1918 Established February 25, 1932 Capital 21.8 billion yen Stock Listed on the First Section of the Tokyo Stock Exchang URL http://www.sakai-chem.co.jp E-mail [email protected]

Head Ofﬁce Matsubara Factory (Cosmetic Ingredients Works)

Other products

Industrial use: Zinc oxide, zinc dust, barium sulfate, Inorganic material high-purity calcium carbonate, barium carbonate, products strontium salts, rutile titanium dioxide, anatase titanium dioxide, etc. Sakai Manufacturing Site Onahama Manufacturing Site Iwaki Plastic additive Metallic soaps, PVC stabilizers (calcium-zinc-based, etc.), products ﬂame retardants, ultraviolet absorbers, etc.

Tokyo Electronic material products Barium titanate, fuel cell materials, etc.

De-Nox (nitrogen oxide) catalysts, dioxin decomposition catalysts, Ozone/VOC treatment catalysts, Sakai Catalyst products reduced nickel catalysts, polyester polymerization catalysts, photocatalysts, copper-based catalysts, catalyst supports for automotive use, etc.

Tokyo Branch

Group companies

Sakai Trading Co., Ltd. Import/export and sales of chemical industrial products, synthetic plastic, electronic materials, and the like Kaigen Pharma Co., Ltd. Manufacture and sales of pharmaceuticals, quasi-pharmaceuticals, health food products, and medical devices ［Locations］ Resino Color Industry Co., Ltd. Manufacture and sale of various dispersions including pigments, coloring agents, and functional inks

Nippon Color Ind. Co., Ltd. Commissioned production of various chemical products, etc. Sakai Chemical Industry Co., Ltd. Sakai Chemical (vietnam) Co.,Ltd Manufacture and sale of plastic additives Katayama Seiyakusyo Co., Ltd. Manufacture of pharmaceutical (new drugs) bulk drugs and intermediates Head Ofﬁce 〒590-8502 5-2 Ebisujima-cho, Sakai-ku, Sakai, Osaka TEL +81-72-223-4111 SC Organic Chemical Co., Ltd. Manufacture and sale of plastic materials, pharmaceutical intermediates, lubricating oil materials, and water treatment agents Tokyo Branch 〒101-0032 2F XYMAX Iwamoto-cho Building, 2-3-3, Iwamoto-cho, Chiyoda-ku, Tokyo TEL +81-3-5823-3721 Kyodo Chemical Co., Ltd. Manufacture and sale of additives for plastics Sakai Manufacturing Site 〒590-0985 5-1 Ebisujima-cho, Sakai-ku, Sakai, Osaka TEL +81-72-223-4115 Osaki Industry Co., Ltd. Manufacture and sale of chemical industrial products, road display materials, electronic materials, and the like Semboku Factory 〒595-0075 1-18 Rinkai-cho, Izumiotsu, Osaka TEL +81-725-33-3881 Joban Kasei Co., Ltd. Manufacture and sale of chemical industrial products Onahama Manufacturing Site 〒971-8183 110 Tajuku, Shimogawa, Izumimachi, Iwaki, Fukushima TEL +81-246-56-5111 Matsubara Factory 〒971-8183 110 Tajuku, Shimogawa, Izumimachi, Iwaki, Fukushima TEL +81-246-56-5111 Yumoto Factory 〒972-8313 1-1 Sawame, Joban Iwagaokamachi, Iwaki, Fukushima TEL +81-246-43-4301 Otsurugi Factory 〒971-8183 382 Otsurugi, Shimogawa, Izumimachi, Iwaki, Fukushima TEL +81-246-56-6610 Corporate Research Laboratories 〒590-0985 5-1 Ebisujima-cho, Sakai-ku, Sakai, Osaka TEL +81-72-223-4117

14 Sakai Chemical Industry Sakai Chemical Industry 15