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Nobel Endeavors in Immunology Introducing Dr SPRING 2012 A PUBLICATION OF SOUTHWESTERN MEDICAL FOUNDATION Nobel Endeavors in Immunology Introducing Dr. Bruce Beutler, UT Southwestern’s fifth Nobel Laureate, and the new Center for the Genetics of Host Defense Southwestern Medical Foundation Board of Trustees 2011-2012 Edward M. Ackerman Joe M. Haggar, III Richard R. Pollock Sara Melnick Albert Nancy S. Halbreich Caren H. Prothro The Heritage Society Rafael M. Anchia LaQuita C. Hall Carolyn Perot Rathjen OF SOUTHWESTERN MEDICAL FOUNDATION Table of Contents Charlotte Jones Anderson Paul W. Harris* Mike Rawlings table of contents Barry G. Andrews Linda W. Hart Jean W. Roach Joyce T. Alban Mr. and Mrs. Thomas E. McCullough Marilyn H. Augur Joe V. (Jody) Hawn, Jr. Linda Robuck Mr. and Mrs. James R. Alexander Christopher F. McGratty Robert D. Rogers Ralph W. Babb, Jr. Jess T. Hay Anonymous (11) Carmen Crews McCracken McMillan Editor Doris L. Bass Frederick B. Hegi, Jr. Catherine M. Rose George A. Atnip# Ferd C. and Carole W. Meyer Nobel Endeavors in Immunology Peter Beck Jeffrey M. Heller* Billy Rosenthal Marilyn Augur* William R. and Anne E. Montgomery Heidi Harris Cannella The threads of Dr. Bruce Beutler’s scientific 3 # Jill C. Bee Julie K. Hersh Lizzie Horchow Routman* Paul M. Bass* Kay Y. Moran career are inextricably woven into the fabric of W. Robert Beavers, M.D. Barbara and Robert Munford Gil J. Besing Thomas O. Hicks Robert B. Rowling* Creative Director UT Southwestern’s history. From intern to mid-career Drs. Paul R. and Robert H. Munger# Jan Hart Black Sally S. Hoglund Stephen H. Sands Rebecca B. Bergstresser Louis Nardizzi, M.D., Ph.D.* Beth Pedersen researcher, he conducted pioneering investigations Cecilia G. Boone David B. Holl John Field Scovell Michael H. Bertino, M.D.* Gerard Noteboom, M.D.# Weber Shandwick of the human immune system, work that would George W. Bramblett, Jr. T. Curtis Holmes, Jr. George E. Seay # # Josephine L. Biddle Rhea T. O’Connor* earn him a Nobel Prize. Now, he expands his George A. Shafer* Daniel H. Branch Shelton G. Hopkins, M.D. Harvey Birsner, M.D. Thomas F. O’Toole Art Director Diane M. Brierley James R. Huffines Karen L. Shuford Jules Bohnn, M.D.* Mrs. Sam Papert, Jr.# tapestry as director of the Center for the Genetics Jean Ann Brock Hunter L. Hunt Lisa K. Simmons Beth Ann Borden Thomas J. Parr, M.D., and Bill Vance of Host Defense. Robert W. Brown, M.D. Rex V. Jobe Ted C. Skokos Nancy L. Branch Joannie Parr Weber Shandwick # # _________ Stephen Butt Judith K. Johnson Richard W. Snyder, II, M.D. Carol A. Brown, M.D.* Selma L. and I. Benjamin Parrill Cherie Brown Patricia M. Patterson* Jeffrey A. Chapman Robert L. Kaminski William T. Solomon* Innovators in Immunity Antonio J. Campdera* Billy Joe Pendley Cover Design Rita C. Clements* Robert W. Korba William S. Spears W. Plack Carr, Jr.* Kurt L. Plaut Jan Pults Dr. Bruce Beutler traveled to Stockholm in Drs. Zhijian “James” Chen, Lora Hooper and Sandra 11 Mary McDermott Cook Peter A. Kraus Paul T. Stoffel Dr. and Mrs. Anthony C. Chang Shirley Pollock*# Schmid all focus on different aspects of immunity, but Richard K. Templeton December to receive the 2011 Nobel Prize David R. Corrigan Wright L. Lassiter, Jr. Emogene B. Clardy Doris E. Porter, P.T. Cover Photograph the common thread of how the body responds to Berry R. Cox Laurence H. Lebowitz Michelle R. Thomas Mr. and Mrs. Robert R. Click Mrs. Ashley (Kathryn) Priddy in physiology or medicine. invading organisms unites them in a common purpose – Harlan R. Crow John I. Levy Jere W. Thompson, Jr. Phyllis M. Coit John Proffitt, M.D. Allison V. Smith Robert H. Dedman, Jr.* Wendy A. Lopez McHenry T. Tichenor, Jr. Frank Crawford, M.D. Muriel Rabiner discovering new ways to prevent and treat disease. Dorothy R. Cullum* W. Paul Radman, D.D.S. Tim Eller Sarah Losinger John C. Tolleson Photographer _________ Kevin and Shari Curran, M.D. Nancy Carol Reddick* Matrice Ellis-Kirk Ann E. Margolin Gifford O. Touchstone David Gresham Edwin R. Daniels* Tom B. Rhodes* Sandra Street Estess Gloria Eulich Martindale Jack C. Vaughn, Jr. Trustee and Officer News Doris Russell Dealey*# Frank Ribelin# Carolyn W. Walker Kathleen Gibson, former president of Citibank Texas 15 Robert A. Estrada William S. McIntyre, IV Johann Deisenhofer, Ph.D. Dr. and Mrs. Leonard Riggs, Jr. Writers Roy Gene Evans John D. McStay W. Kelvin Walker Anne and Brian Dethrow Jack D. Russell Amanda Billings and Bank of America, Dallas, has joined Southwestern Andersen C. Fisher Susan Byrne Montgomery Tom Walter Grant A. Dove# Mr. and Mrs. John Carl Rutledge Medical Foundation as executive vice president. I. D. (Nash) Flores, III Kay Y. Moran Carol R. West, C.P.A. Joyce Allison Eberts and Eleanor R. Salomon Randal Daugherty Terry J. Flowers Jennifer T. Mosle Jimmy Westcott John P. Eberts, M.D. Stephen Raymond Salomon Rachel Skei Donihoo _________ # # # Kay Carter Fortson Mike A. Myers George W. Wharton, M.D. Mack M. Elliott Hortense and Morton Sanger # Donna Steph Hansard Planned Giving Alan D. Friedman Charles E. Nearburg Laura Wheat Gene and Charlotte Emery Lorraine Sulkin Schein Pamela and Roy Gene Evans* Dr. # and Mrs. John W. Schermerhorn Casey Poe Dr. Herbert S. Salomon’s life inspired many, including his 16 William H. Gerlach, D.D.S. Stephen Ozanne, M.D. Martha S. Williams Richard Ferguson Mr. and Mrs. William L. Schilling brother and sister-in-law, who have made bequests Judy Gibbs Teresa Haggerty Parravano Fritzi G. Woods Amanda Siegfried Dave and Lori Folz Hans J. Schnitzler in their wills as well as annual donations to support a Kathleen M. Gibson Carlos G. Peña Kneeland C. Youngblood Robert G. Freeman, M.D.# F. Michael Schultz, M.D.* Joseph M. (Jody) Grant T. Boone Pickens Gretchen and Gerald Fronterhouse Bette Claire Schuttler# Editorial comments and scholarship fund in Dr. Salomon’s honor. Rolf R. Haberecht Daniel K. Podolsky, M.D.* * Executive Committee Dr. and Mrs. Norman F. Gant Sarah M.# and Charles E. Seay*# contributions are welcome _________ # Ronald W. Haddock J. Blake Pogue Mr. and Mrs. John Robert Gavlick, Sr. William D. Seybold, M.D.* Send correspondence to: David Ginn, M.D.* George and Shirley Shafer Making a Difference # # # Southwestern Medical Foundation Southwestern Medical Foundation Honorary Trustees Mr. and Mrs. F.B. Pete Goldman* Doyle L. Sharp, M.D.* Dr. Michael Brown notes: “Dr. Beutler’s Jimmie LaFollette, the Sweetheart Ball, the A.L. Chilton 18 Mr. and Mrs. Joe M. Graham Tom and Dorothy Shockley Reagan Place at Old Parkland approach beautifully complements the work Foundation, Dorothy and Roger Hirl, Bette Ruth Sharp Altshuler Lee Halford, Sr. Nancy Penson G. Thomas Graves III Mr. and Mrs. George A. (Tom) Shutt* # 3963 Maple Ave., Suite 100 Gilbert Aranza Howard Hallam Jack Pew, Jr. L. Ruth Guy, Ph.D. John S. Smale, M.D. of other UT Southwestern scientists who Claire Schuttler, the Hoblitzelle Foundation, and James David W. Biegler Charles M. Hansen, Jr. Charles H. Pistor Nancy and Jeremy Halbreich Dr. and Mrs. Neal C. Small Dallas, Texas 75219 Cleo Thompson are all making a difference # # study similar problems.” Gene H. Bishop John P. (Jack) Harbin Kathryn Priddy Sydney and Wallace Hall* Ellen K. and Robert L. Solender* # Office: 214-351-6143 with their gifts to Southwestern Medical Foundation. Albert C. Black, Jr. Lyda Hill Mary Stewart Ramsey Nancy B. Hamon* William T. Solomon* Stuart M. Bumpas Laurence E. Hirsch Tom B. Rhodes John P. Harbin Alayne W. Sprague Fax: 214-352-9874 _________ Dr. and Mrs. Thomas W. Harris* Charles C. Sprague, M.D.*# W. Plack Carr, Jr. James M. Hoak Leonard M. Riggs, Jr., M.D. E-mail: [email protected] # Edward H. Cary, III Keith W. Hughes John L. Roach Helen B. and Arthur E. Hewett Ronald G. Steinhart* In Good Company # George Volk Charlton Walter J. Humann Pete Schenkel Joyce A. Hendrickson Eleanor P. Stevens Mary McDermott Cook, Vester Hughes and Robert 24 Mr. # and Mrs. Donald R. Hibbert* S. C. Stewart, M.D.* Dan W. Cook, III Ray L. Hunt Paul R. Seegers Korba were honored with the Charles Cameron Sprague Ed Daniels Philip R. Jonsson Carl Sewell, Jr. Lyda Hill Sally Seay Stout* Joe D. Denton Darrell E. Jordan George A. (Tom) Shutt J. Roger and Dorothy A. Hirl Douglas H. Unger, M.D.* Community Service Award in October, and in Robert J. DiNicola Dale V. Kesler Roger T. Staubach James M. Hoak Claire Elaine Vial and Robert G. Vial February, medical students had the opportunity to meet # # Thomas M. Dunning Gary Kusin A. Starke Taylor, Jr. Edmund M. Hoffman* Irene Wadel # and thank the benefactors of their medical Thomas J. Engibous David M. Laney Joanne Stroud, Ph.D. Mr. and Mrs. S. Roger Horchow Carolyn W. and Thomas C. Walker # education at the annual scholarship luncheon. Gregg L. Engles Thomas C. Leppert J. Liener Temerlin Drs. Susan Hotz and Michael Shiekh Tim Wallace Dr. J. B. Howell# Jean and Tom Walter Robert Ted Enloe, III Irvin L. Levy Ellen C. Terry _________ # Jerry Farrington Lester A. Levy, Sr. Jim L. Turner William C. Huber Mr. and Mrs. Richard L. Walton Robert I. Fernandez Wales Madden, Jr. John J. Veatch, Jr. Keith and Cherie Hughes Dr. Elgin W. and Karen G. Ware Endowments and Gifts Lee Fikes Margaret McDermott Kent Waldrep Robert and Myra Hull Dr. and Mrs. Clark Watts* Thanks to those who contribute to centers, chairs, 27 # David L. Florence Harvey R. Mitchell W. Ray Wallace Mrs. Morris I. Jaffe* Arthur G. Weinberg, M.D. # # professorships, scholarships and other special projects for Edwin S.
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