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In cooperation with DIE WOCHE SPEZIAL >> Autographs>vs.>#NobelSelfie Special >> Big>Data>–>not>a>big>deal,> Edition just>another>tool >> Why>Don’t>Grasshoppers> Catch>Colds? SCIENCE SUMMIT The>64th>Lindau>Nobel>Laureate>Meeting> devoted>to>Physiology>and>Medicine More than 600 young scientists came to Lindau to meet 37 Nobel laureates CAREER WONGSANIT > Women>to>Women: SUPHAKIT > / > Science>and>Family FOTOLIA INFLAMMATION The>Stress>of>Ageing > FLASHPICS > / > MEETINGS > FOTOLIA LAUREATE > CANCER RESEARCH NOBEL > LINDAU > / > J.>Michael>Bishop>and GÄRTNER > FLEMMING > JUAN > / the>Discovery>of>the>first> > CHRISTIAN FOTOLIA Human>Oncogene EDITORIAL IMPRESSUM Chefredakteur: Prof. Dr. Carsten Könneker (v.i.S.d.P.) Dear readers, Redaktionsleiter: Dr. Daniel Lingenhöhl Redaktion: Antje Findeklee, Jan Dönges, Dr. Jan Osterkamp where>else>can>aspiring>young>scientists> Ständige Mitarbeiter: Lars Fischer Art Director Digital: Marc Grove meet>the>best>researchers>of>the>world> Layout: Oliver Gabriel Schlussredaktion: Christina Meyberg (Ltg.), casually,>and>discuss>their>research,>or>their> Sigrid Spies, Katharina Werle Bildredaktion: Alice Krüßmann (Ltg.), Anke Lingg, Gabriela Rabe work>–>or>pressing>global>problems?>Or> Verlag: Spektrum der Wissenschaft Verlagsgesellschaft mbH, Slevogtstraße 3–5, 69126 Heidelberg, Tel. 06221 9126-600, simply>discuss>soccer?>Probably>the>best> Fax 06221 9126-751; Amtsgericht Mannheim, HRB 338114, UStd-Id-Nr. DE147514638 occasion>is>the>annual>Lindau>Nobel>Laure- Geschäftsleitung: Markus Bossle, Thomas Bleck Marketing und Vertrieb: Annette Baumbusch (Ltg.) Leser- und Bestellservice: Helga Emmerich, Sabine Häusser, ate>Meeting>in>the>lovely>Bavarian>town>of> Ute Park, Tel. 06221 9126-743, E-Mail: [email protected] Lindau>on>Lake>Constance. Die Spektrum der Wissenschaft Verlagsgesellschaft mbH ist Kooperati- onspartner des Nationalen Instituts für Wissenschaftskommunikation Daniel>Lingenhöhl> GmbH (NaWik). Das NaWik ist ein Institut der Klaus Tschira Stiftung Redaktionsleiter>Spektrum>–>Die>Woche GmbH und des Karlsruher Instituts für Technologie. Wissenschaftlicher. Direktor des NaWik ist Spektrum-Chefredakteur Dr. Carsten Könneker. E-Mail:>[email protected] Each>year,>a>number>of>journalists>and> Twitter:>@lingenhoehl bloggers>are>invited>to>these>meetings.> Bezugspreise: Einzelausgabe € 1,49. Im Abonnement jährlich: € 39,95; ermäßigt € 30,00. They>cover>the>Lindau>event>from>a>subject- Alle Preise verstehen sich inkl. Umsatzsteuer. Anzeigen: Wenn Sie an Anzeigen in »Spektrum – Die Woche« interes- specific,>as>well>as>from>a>personal>perspec- siert sind, schreiben Sie bitte eine Mail an [email protected] tive.>This>special>edition>of>Spektrum.de‘s>> Sämtliche Nutzungsrechte an dem vorliegenden Werk liegen bei der Spektrum der Wissenschaft Verlagsgesellschaft mbH. Jegliche »Woche«>presents>the>best>stories>in>Eng- Nutzung des Werks, insbesondere die Vervielfältigung, Verbreitung, öffentliche Wiedergabe oder öffentliche Zugänglichmachung, ist lish>–>suiting>the>international>level>of>this> ohne die vorherige schriftliche Einwilligung des Verlags unzulässig. Jegliche unautorisierte Nutzung des Werks berechtigt den Verlag unique>event. zum Schadensersatz gegen den oder die jeweiligen Nutzer. Bei jeder autorisierten (oder gesetzlich gestatteten) Nutzung des Werks ist die In cooperation with folgende Quellenangabe an branchenüblicher Stelle vorzunehmen: © 2014 (Autor), Spektrum der Wissenschaft Verlagsgesellschaft Now,>enjoy>our>stories! mbH, Heidelberg. Jegliche Nutzung ohne die Quellenangabe in der vorstehenden Form berechtigt die Spektrum der Wissenschaft Verlagsgesellschaft mbH zum Schadensersatz gegen den oder die jeweiligen Nutzer. Bildnachweise: Wir haben uns bemüht, sämt- liche Rechteinhaber von Abbildungen zu ermitteln. Sollte dem Folgen Sie uns: Verlag gegenüber der Nachweis der Rechtsinhaberschaft geführt werden, wird das branchenübliche Honorar nachträglich gezahlt. Für unaufgefordert eingesandte Manuskripte und Bücher über - nimmt die Redaktion keine Haftung; sie behält sich vor, Leserbriefe zu kürzen. 2 INHALT CAREER 14 CANCER RESEARCH Women>to>Women:> J.>Michael>Bishop>and>the> Science>and>Family 08 GAERTNER Discovery>of>the>first>Human> > JUAN > / > RAVEN Oncogene > ISTOCKPHOTO KATHLEEN INFLAMMATION DATA-DRIVEN SCIENCE 17 25 MEETINGS The>Stress> > Big>Data>–>not>a>big>deal,> LAUREATE > just>another>tool of>Ageing NOBEL > LINDAU > / > REISINGER > FLEMMING > CARSTEN > / > CHRISTIAN FOTOLIA 05 DEMOGRAPHY 28 SCIENCE PLACES 42 BACTERIAL INFECTIONS The>Future>Belongs>to>Women> Virtual>Visit>at>the>Institut> On>Man>and>Microbes>–> Scientists>and>CEOs Pasteur>in>Paris Barry>Marshall 07 WHO WAS THERE? 31 SCIENCE COMMUNICATION 45 MEDICAL RESEARCH Laureates>at>the>64th>Lindau> Randy>Schekman:>Honest> Physician-Scientists:> Nobel>Laureate>Meeting Exchange>of>Knowledge An>Endangered>Species? 11 CANCER RESEARCH 36 VIRUS RESEARCH 51 SYNTHETIC BIOLOGY Research>for>the>Dogs>–> Could>A>Cow>Virus>Cause> Synthetic>Genes,>Synthetic>Cells> Young>Scientist>profiles Colon>Cancer? –>Synthetic>Life 22 IMMUNE SYSTEM 39 INFECTIOUS DISEASES 55 FANDOM Why>Don’t>Grasshoppers> From>Mice>and>Fruit>Flies>Towards> Autographs>vs.>#NobelSelfie Catch>Colds? Novel>Infection>Treatment 3 The Lindau Nobel Laureate Meetings Since 1951, Nobel Laureates and young scientists from all around the globe come together at Lindau to discuss science and society. The Lindau Nobel Laureate Meetings foster the Exhibitions Nobel Portraits Annual Meetings cross-cultural and inter-generational exchange Sketches of Science Medicine | Chemistry | Physics | Economics of knowledge and help to create new networks Discoveries for the future. All articles in this edition have all been Mediatheque published in the Lindau Blog. Are you interested Lectures Background in more posts on global science issues, the latest Nobel Labs 360° scientific developments, intriguing personal Penzias Painting Public Lectures stories and the interplay between science and MINT-Education society? Thinking about taking part in the Webinars discussion or contributing yourself? Visit the Events Lindau Blog and become a guest blogger. Weblog Social Media Art Catalogues www.lindau-nobel.org Stakeholder Initiatives Educational Books Teaching Spirit Innovation Forum Publications blog.lindau-nobel.org Alumni twitter.com/lindaunobel facebook.com/LindauNobelLaureatesMeeting 4 DEMOGRAPHY The>Future>Belongs>to> Women>Scientists>and>CEOs Christine Gorman Christine>Gorman>about>Hans>Rosling’s>impressive> Presentation>at>the>Opening>of>the>64th>Lindau>Nobel> Laureate>Meeting. > MEETINGS > LAUREATE > NOBEL > LINDAU > / > FLEMMING > Hans Rosling talks about future population CHRISTIAN 5 or the first time in its 64-year influenced by preconceived ideas of what whenever we talk about the next 50 to 100 history, a prestigious, invita- the world is like. years of life on earth. »If you score worse tion-only meeting of young sci- Hans Rosling, the always entertaining than random, then the problem is not lack entists and Nobel Laureates is and informative professor of international of knowledge«, Rosling told the audience. made up of more women than health at the Karolinska Institute in Swe- It is about why the perception of the world Fmen. Between 3,000 and 4,000 graduate den, posed four questions of the audience. divided between »developed« and »devel- and post-graduate students in science ap- Thanks to the interactive clickers available oping« countries refuses to budge from so plied to attend the Lindau Nobel Laureate to all participants, we quickly discovered many perceptive people’s fundamental Meeting, held every year in a picturesque that less than 10% of the dignitaries, scien- understanding of the world. Bavarian town near the southern tip of tists and budding scientists knew that 80 Who do you think scores better than the Lake Constance in Germany. »This year, for percent of all children around the world chimpanzees when Rosling’s performs this the first time, more young women than are vaccinated against measles (most pop quiz? The CEOs of international com- men have qualified« for the coveted 600 guessed either 20 percent or 50 percent) or panies. < spots, Countess Bettina Bernadotte told that the number of children that will be participants at the opening ceremony in born in the coming decades is actually not You can read more about Rosling’s quizzes in Lindau, Germany. expected to grow significantly beyond the this BBC News article. But that was probably not the most sur- number that are currently born. (It’s the prising thing most people learned this af- number of adults that is going to shoot up, ternoon. More surprising was that even boosting world population to 9 billion by this highly educated group did not do so 2050, up from 7 billion now.) A greater Sie suchen eine well on a pop quiz about some basic facts number of participants came up with the Mathematikerin about global health. Before you make any correct answer for the other two questions, für ein Interview? snide remarks, realize that their answers but the gap between perception and reality were in line with those given by citizens of was greatest for measles vaccination and the U.S.,U.K. and Sweden as well as some of projected number of children. Rosling’s fellow professors. In fact, the only The point, as Rosling explained, was not group that scored better were a bunch of to embarrass a bunch of scientists, but to chimpanzees at a Swedish zoo, who, be- help them to realize some of the very www.academia-net.de