OR51E1 Antibody (C-Terminus) Rabbit Polyclonal Antibody Catalog # ALS10457

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OR51E1 Antibody (C-Terminus) Rabbit Polyclonal Antibody Catalog # ALS10457

10320 Camino Santa Fe, Suite G San Diego, CA 92121 Tel: 858.875.1900 Fax: 858.622.0609 OR51E1 Antibody (C-Terminus) Rabbit Polyclonal Antibody Catalog # ALS10457 Specification OR51E1 Antibody (C-Terminus) - Product Information Application IHC Primary Accession Q8TCB6 Reactivity Human Host Rabbit Clonality Polyclonal Calculated MW 35kDa KDa OR51E1 Antibody (C-Terminus) - Additional Information Gene ID 143503 Anti-OR51E1 antibody ALS10457 IHC of Other Names human prostate, glands. Olfactory receptor 51E1, D-GPCR, G-protein coupled receptor 164, Olfactory receptor 52A3, Prostate-overexpressed G OR51E1 Antibody (C-Terminus) - protein-coupled receptor, Prostate-specific Background G protein-coupled receptor 2, OR51E1, GPR164, OR51E1P, OR52A3P, POGR, PSGR2 Odorant receptor. Target/Specificity OR51E1 Antibody (C-Terminus) - Human OR51E1. BLAST analysis of the References peptide immunogen showed no homology with other human proteins. Weigle B.,et al.Biochem. Biophys. Res. Commun. 322:239-249(2004). Reconstitution & Storage Suwa M.,et al.Submitted (JUL-2001) to the Long term: -70°C; Short term: +4°C EMBL/GenBank/DDBJ databases. Weng J.,et al.Int. J. Cancer Precautions 118:1471-1480(2006). OR51E1 Antibody (C-Terminus) is for research use only and not for use in Ota T.,et al.Nat. Genet. 36:40-45(2004). diagnostic or therapeutic procedures. Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. OR51E1 Antibody (C-Terminus) - Protein Information Name OR51E1 Synonyms GPR164, OR51E1P, OR52A3P, POGR, PSGR2 Function Odorant receptor. Page 1/2 10320 Camino Santa Fe, Suite G San Diego, CA 92121 Tel: 858.875.1900 Fax: 858.622.0609 Cellular Location Cell membrane; Multi-pass membrane protein Tissue Location Highly expressed in prostate. Very low levels may be detected in some other tissues, such as placenta, skeletal muscle, heart, ovary and testis. Up-regulated in prostate cancers Volume 50 µl OR51E1 Antibody (C-Terminus) - Protocols Provided below are standard protocols that you may find useful for product applications. • Western Blot • Blocking Peptides • Dot Blot • Immunohistochemistry • Immunofluorescence • Immunoprecipitation • Flow Cytomety • Cell Culture Page 2/2 Powered by TCPDF (www.tcpdf.org).

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The Potential Druggability of Chemosensory G Protein-Coupled Receptors
International Journal of Molecular Sciences Review Beyond the Flavour: The Potential Druggability of Chemosensory G Protein-Coupled Receptors Antonella Di Pizio * , Maik Behrens and Dietmar Krautwurst Leibniz-Institute for Food Systems Biology at the Technical University of Munich, Freising, 85354, Germany; [email protected] (M.B.); [email protected] (D.K.) * Correspondence: [email protected]; Tel.: +49-8161-71-2904; Fax: +49-8161-71-2970 Received: 13 February 2019; Accepted: 12 March 2019; Published: 20 March 2019 Abstract: G protein-coupled receptors (GPCRs) belong to the largest class of drug targets. Approximately half of the members of the human GPCR superfamily are chemosensory receptors, including odorant receptors (ORs), trace amine-associated receptors (TAARs), bitter taste receptors (TAS2Rs), sweet and umami taste receptors (TAS1Rs). Interestingly, these chemosensory GPCRs (csGPCRs) are expressed in several tissues of the body where they are supposed to play a role in biological functions other than chemosensation. Despite their abundance and physiological/pathological relevance, the druggability of csGPCRs has been suggested but not fully characterized. Here, we aim to explore the potential of targeting csGPCRs to treat diseases by reviewing the current knowledge of csGPCRs expressed throughout the body and by analysing the chemical space and the drug-likeness of ﬂavour molecules. Keywords: smell; taste; ﬂavour molecules; drugs; chemosensory receptors; ecnomotopic expression 1. Introduction Thirty-five percent of approved drugs act by modulating G protein-coupled receptors (GPCRs) [1,2]. GPCRs, also named 7-transmembrane (7TM) receptors, based on their canonical structure, are the largest family of membrane receptors in the human genome.
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Expression Profile of Ectopic Olfactory Receptors Determined by Deep Sequencing
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Explorations in Olfactory Receptor Structure and Function by Jianghai
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