The Spectrum of Autoimmune Diseases

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The Spectrum of Autoimmune Diseases Sarah Ballantyne, PhD 1717 The Spectrum of Autoimmune Diseases The following is a list of diseases that are either confirmed autoimmune diseases or for which there is very strong scientific evidence for autoimmune origins: Acute brachial neuropathy (also Atrophic polychondritis (also known Besnier-Boeck disease (also known A known as acute brachial radiculitis, as systemic chondromalacia and as sarcoidosis) neuralgic amyotrophy, brachial relapsing polychondritis) Bickerstaff’s encephalitis neuritis, brachial plexus neuropathy, Autoimmune angioedema Bladder pain syndrome (also known brachial plexitis, and Parsonage- Autoimmune aplastic anemia (also as interstitial cystitis) Turner syndrome) known as aplastic anemia) Brachial neuritis (also known as Acute disseminated Autoimmune cardiomyopathy brachial plexus neuropathy, brachial encephalomyelitis (ADEM) Autoimmune dysautonomia plexitis, Parsonage-Turner syndrome, Acute necrotizing hemorrhagic acute brachial neuropathy, acute Autoimmune hemolytic anemia leukoencephalitis brachial radiculitis, and neuralgic Acute parapsoriasis (also known as Autoimmune hepatitis amyotrophy) acute guttate parapsoriasis, acute Autoimmune hyperlipidemia Bullous pemphigoid pityriasis lichenoides, parapsoriasis Autoimmune immunodeficiency Castleman’s disease (also varioliformis, Mucha-Habermann C known as giant lymph node disease, and parapsoriasis or Autoimmune inner ear disease hyperplasia, lymphoid hamartoma, pityriasis lichenoides et varioliformis (AIED) and angiofollicular lymph node acuta) Autoimmune myocarditis hyperplasia) Addison’s disease (also Autoimmune pancreatitis Celiac disease (also known as known as chronic adrenal Autoimmune peripheral neuropathy coeliac disease and celiac sprue) insufficiency, hypocortisolism, and (also known as peripheral hypoadrenalism) neuropathy) Chagas disease (also known as American trypanosomiasis) Adult linear IgA disease (also known Autoimmune polyendocrine as linear IgA disease) syndrome (APS) Chorea minor (also known as Sydenham’s chorea) Agammaglobulinemia Autoimmune polyglandular Chronic adrenal insufficiency Allergic granulomatosis (also known syndrome, Types 1, 2, and 3 (also known as hypocortisolism, as Churg-Strauss syndrome) Autoimmune progesterone hypoadrenalism, and Addison’s Alopecia areata (AA; also known as dermatitis disease) spot baldness) Autoimmune retinopathy Chronic focal encephalitis (CFE; American trypanosomiasis (also Autoimmune thrombocytopenic also known as Rasmussen’s known as Chagas disease) purpura (ATP; also known as encephalitis) Amyloidosis thrombotic thrombocytopenic Chronic inflammatory demyelinating Anaphylactoid purpura (also known purpura and idiopathic polyneuropathy (CIDP) thrombocytopenic purpura) as purpura rheumatica and Henoch- Chronic lymphocytic thyroiditis (also Schönlein purpura) Autoimmune thyroid disease known as Hashimoto’s thyroiditis) Angiofollicular lymph node Autoimmune urticaria Chronic recurrent multifocal hyperplasia (also known as Autoimmune uveitis (also known as ostomyelitis (CRMO) Castleman’s disease, giant lymph uveitis) Chronic urticaria as a manifestation node hyperplasia, and lymphoid Axonal and neuronal neuropathies of venulitis (also known as urticarial hamartoma) Balo disease (also known as Balo vasculitis) Ankylosing spondylitis (AS; also B concentric sclerosis) Churg-Strauss syndrome (also known as Bekhterev’s disease and known as allergic granulomatosis) Marie-Strümpell disease) Behçet’s disease (also known as Silk Road disease) Cicatricial pemphigoid (also known Anti-GBM or anti-TBM nephritis Bekhterev’s disease (also known as as benign mucosal pemphigoid) Antiphospholipid syndrome (APS ankylosing spondylitis and Marie- Cogan’s syndrome or APLS; also known as Hughes Strümpell disease) syndrome) Cold agglutinin disease Benign mucosal pemphigoid (also Aplastic anemia (also known as Congenital heart block known as cicatricial pemphigoid, autoimmune aplastic anemia) benign mucous membrane Coxsackie viral myocarditis Arthritis psoriatica (also known as pemphigoid, scarring pemphigoid, Cranial arteritis (also known as arthropathic psoriasis and psoriatic and ocular cicatricial pemphigoid) Horton disease, giant cell arteritis, arthritis) Berger’s disease (also known as and temporal arteritis) Arthropathic psoriasis (also known IgA nephropathy and synpharyngitic CREST syndrome (also known as arthritis psoriatica and psoriatic glomerulonephritis) as limited systemic sclerosis or arthritis) scleroderma) 1818 The Paleo Approach Crohn’s disease H Hashimoto’s thyroiditis (also known Landry’s paralysis (also known as Crow-Fukase syndrome (also as chronic lymphocytic thyroiditis) Miller Fisher syndrome and Guillain- known as Takatsuki disease, PEP Hashimoto’s encephalitis or Barré syndrome) syndrome, and POEMS syndrome) encephalopathy Leukocytoclastic vasculitis Cryptogenic fibrosing alveolitis Henoch-Schönlein purpura (also Lichen planus (CFA; also known as idiopathic known as anaphylactoid purpura Lichen sclerosus pulmonary fibrosis and fibrosing and purpura rheumatica) Ligneous conjunctivitis alveolitis) Herpes gestationis (also known as Limited systemic sclerosis (also Demyelinating neuropathies (also gestational pemphigoid) known as limited systemic D known as idiopathic inflammatory Horton disease (also known as giant scleroderma and CREST syndrome) demyelinating diseases) cell arteritis, temporal arteritis, and Linear IgA disease (LAD; also Dermatomyositis (DM) cranial arteritis) known as adult linear IgA disease) Devic’s disease (also known as Hughes syndrome (also known as Lupus (also known as systemic neuromyelitis optica) antiphospholipid syndrome) lupus erythematosus) Diabetes mellitus type 1 (also known Hypocortisolism (also known as Lyme disease, chronic as insulin-dependent diabetes and hypoadrenalism, Addison’s disease, type 1 diabetes) and chronic adrenal insufficiency) Lymph node syndrome (also known as mucocutaneous lymph node Discoid lupus erythematosus (DLE) Hypogammaglobulinemia syndrome and Kawasaki disease) Dressler’s syndrome (also known as Idiopathic inflammatory bowel Lymphoid hamartoma (also known postmyocardial infarction syndrome) I disease (includes both Crohn’s as angiofollicular lymph node disease and ulcerative colitis) Duhring’s disease (also known as hyperplasia, Castleman’s disease, dermatitis herpetiformis) Idiopathic inflammatory and giant lymph node hyperplasia) demyelinating diseases (also known Endocarditis lenta (also known as Marchiafava-Micheli syndrome (also as demyelinating neuropathies) E subacute bacterial endocarditis) M known as paroxysmal nocturnal Endometriosis Idiopathic pulmonary fibrosis (IPF; hemoglobinuria) also known as cryptogenic fibrosing Eosinophilic esophagitis or Marie-Strümpell disease (also alveolitis and fibrosing alveolitis) gastroenteritis known as ankylosing spondylitis Idiopathic thrombocytopenic Eosinophilic fasciitis and Bekhterev’s disease) purpura (ITP; also known as Ménière’s disease Erythema nodosum thrombocytopenic purpura and Erythroblastopenia (also known as autoimmune thrombocytopenic Microscopic polyangiitis (also pure red cell aplasia) purpura) known as microscopic polyarteritis) Essential mixed cryoglobulinemia IgA nephropathy (also known as Miller Fisher syndrome (also known as Guillain-Barré syndrome and Evans syndrome synpharyngitic glomerulonephritis and Berger’s disease) Landry’s paralysis) Experimental allergic Mixed connective tissue disease encephalomyelitis (EAE) IgG4-related sclerosing disease (MCTD; also known as Sharp’s Inclusion body myositis Fibrosingalveolitis (also known as syndrome) F idiopathic pulmonary fibrosis and Insulin-dependent diabetes (also Moersch-Woltman condition (also cryptogenic fibrosing alveolitis) known as type 1 diabetes and known as stiff person syndrome) Gestational pemphigoid (also known diabetes mellitus type 1) Mooren’s ulcer G as herpes gestationis) Interstitial cystitis (also known as Mucha-Habermann disease Giant cell arteritis (also known as bladder pain syndrome) (also known as acute guttate temporal arteritis, cranial arteritis, Juvenile diabetes (also known as parapsoriasis, acute parapsoriasis, and Horton disease) J diabetes mellitus type 1, insulin- acute pityriasis lichenoides, dependent diabetes, and type 1 Giant lymph node hyperplasia (also and parapsoriasis or pityriasis diabetes) known as lymphoid hamartoma, lichenoides et varioliformis acuta) angiofollicular lymph node Juvenile rheumatoid arthritis (also Mucocutaneous lymph node hyperplasia, and Castleman’s known as juvenile idiopathic arthritis syndrome (also known as lymph disease) and Still’s disease) node syndrome and Kawasaki Glomerulonephritis Kawasaki syndrome (also known disease) K as Kawasaki disease, lymph node Goodpasture’s syndrome Multiple sclerosis syndrome, and mucocutaneous Granulomatosis with polyangiitis lymph node syndrome) Myasthenia gravis (GPA; also known as Wegener’s Myositis granulomatosis) Kussmaul-Maier disease (also known as polyarteritis nodosa) Narcolepsy Graves’ disease N Lambert-Eaton syndrome Neuromyelitis optica (also known as Guillain-Barré syndrome (also L (also known as Lambert-Eaton Devic’s disease) known as Landry’s paralysis and myasthenic syndrome) Miller Fisher syndrome) Neutropenia Sarah Ballantyne, PhD 1919 Ocular cicatricial pemphigoid Progressive hemifacial atrophy Stiff person syndrome (also known O (also known as benign mucous (also known as Parry Romberg as Moersch-Woltman condition) membrane pemphigoid and scarring syndrome) Still’s disease (also known as
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