Diseases/Symptoms Reported to Be Associated with Lyme Disease
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55400-Neuropathdementiav5
08/11/2019 Bodian silver method Neuropathology of the Dementia Spectrum Charles Duyckaerts Escourolle Neuropathology Lab Alzheimer-Prion team ICM Pitié-Salpêtrière Senile plaquePitié-Salpêtrière Neurofibrillary tangle 12 Aβ accumulation + tauopathy = Alzheimer disease (please note: no neuronal loss in criteria) Pitié-Salpêtrière Pitié-Salpêtrière 34 1 08/11/2019 BRAAK STAGES : tau pathology THAL PHASES : Aβ pathology I II 1 23 III IV 4 5 V VI Braak and Braak. Acta Neuropathol 1991 Thal et al. Neurology 2002 Pitié-Salpêtrière Pitié-Salpêtrière 56 Pick’s circumscribed atrophy Pitié-Salpêtrière α-synuclein IHC Pitié-Salpêtrière 78 2 08/11/2019 Dementia (~1920) Alzheimer disease Pick disease (Pick circumscribed atrophy) Alzheimer A (1911) Uber eigenartige Krankheitsfälle des späteren Alters. Zentralblatt Gesam Neurol Psychiat 4: 356- Pitié-Salpêtrière Pitié-Salpêtrière 385 910 Pick disease Pick disease (Pick body disease) is also a tauopathy Tau IHC Pitié-Salpêtrière Pitié-Salpêtrière 11 12 3 08/11/2019 Fronto-temporal dementia with 1- behavioral changes 2- semantic dementia 3- progressive non-fluent aphasia Pick disease (with Pick bodies) « Pick without Pick body » R. Escourolle. 1957 & S. Brion Type C of Tissot, Constantinidis & Richard, 1975 Previously « Atypical Pick disease » Knopman DS, Mastri AR, Frei WH, Sung JH, Rustan T (1990) Dementia lacking distinctive histologic feature: a common non-Alzheimer degenerative dementia. Neurology 40: 251-256 Pitié-Salpêtrière Pitié-Salpêtrière 13 14 Mutations in the tau gene in frontotemporal dementia -
ICD-10-CM TABULAR LIST of DISEASES and INJURIES 2018 Addenda No Change Chapter 1 No Change Certain Infectious and Parasitic Diseases (A00-B99)
ICD-10-CM TABULAR LIST of DISEASES and INJURIES 2018 Addenda No Change Chapter 1 No Change Certain infectious and parasitic diseases (A00-B99) No Change Intestinal infectious diseases (A00-A09) No Change A04 Other bacterial intestinal infections No Change A04.7 Enterocolitis due to Clostridium difficile Add A04.71 Enterocolitis due to Clostridium difficile, recurrent Add A04.72 Enterocolitis due to Clostridium difficile, not specified as recurrent No Change A05 Other bacterial foodborne intoxications, not elsewhere classified No Change Excludes1: Revise from Clostridium difficile foodborne intoxication and infection (A04.7) Revise to Clostridium difficile foodborne intoxication and infection (A04.7-) No Change Helminthiases (B65-B83) No Change B81 Other intestinal helminthiases, not elsewhere classified No Change Excludes1: Revise from angiostrongyliasis due to Parastrongylus cantonensis (B83.2) Revise to angiostrongyliasis due to: Add Angiostrongylus cantonensis (B83.2) Add Parastrongylus cantonensis (B83.2) No Change B81.3 Intestinal angiostrongyliasis Revise from Angiostrongyliasis due to Parastrongylus costaricensis Revise to Angiostrongyliasis due to: Add Angiostrongylus costaricensis Add Parastrongylus costaricensis No Change Chapter 2 No Change Neoplasms (C00-D49) No Change Malignant neoplasms of ill-defined, other secondary and unspecified sites (C76-C80) No Change C79 Secondary malignant neoplasm of other and unspecified sites Delete Excludes2: lymph node metastases (C77.0) No Change C79.1 Secondary malignant neoplasm of bladder -
Case Report Reversible Cortical Blindness and Convulsions with Cyclosporin a Toxicity in a Patient Undergoing Allogeneic Peripheral Stem Cell Transplantation
Bone Marrow Transplantation, (1997) 20, 793–795 1997 Stockton Press All rights reserved 0268–3369/97 $12.00 Case report Reversible cortical blindness and convulsions with cyclosporin A toxicity in a patient undergoing allogeneic peripheral stem cell transplantation B Madan and SA Schey Department of Haematology, Guy’s Hospital, London, UK Summary: one course each of MACE (mitozantrone on days 1, 3 and 5, cytosine arabinoside on days 1–10, etoposide on days 1– A 40-year-old woman underwent allogeneic peripheral 5) and ICE (idarubicin on days 1 and 2, cytosine arabino- blood stem cell transplantation for relapsed AML-M6. side on days 1–3, etoposide on days 1–3). She achieved She developed graft-versus-host disease on day +15 complete remission after her first induction but relapsed post-transplant, for which she was treated with cyclo- within 1 month of completion of ICE chemotherapy. In sporin A and methyl prednisolone. On day +19 she March 1996 she was given mitoxantrone, cytosine arabino- developed cortical blindness, headache and convulsions side and PSC-833 (a cyclosporin D analogue) as per relapse which were associated with white matter changes on protocol and achieved complete remission. In July 1996, MRI scanning of the head and elevated cyclosporin A she received an allogeneic peripheral stem cell transplant levels. A diagnosis of cyclosporin A encephalopathy was from her HLA-identical sister following conditioning with made and cyclosporin A was discontinued. Her vision cyclophosphamide and total body irradiation. She received recovered completely after 48 h and the other symptoms cyclosporin A as prophylaxis for graft-versus-host disease. -
Cortical Blindness: Etiology, Diagnosis, and Prognosis
Cortical Blindness: Etiology, Diagnosis, and Prognosis Michael S. Aldrich, MD," Anthony G. Alessi, MD," Roy W. Beck, MD,$ and Sid Gilman, MDI We examined 15 patients with cortical blindness, reviewed the records of 10 others, and compared these 25 patients to those in previous studies of cortical blindness. Although cerebrovascular disease was the most common cause in ow series, surgery, particularly cardiac surgery, and cerebral angiography were also major causes. Only 3 patients denied their blindness, although 4 others were unaware of their visual loss. Electroencephalograms (EEGs) were performed during the period of blindness in 20 patients and all recordings were abnormal, with absent alpha rhythm. Visual evoked potentials recorded during blindness were abnormal in 15 of 19 patients, but did not correlate with the severity of visual loss or with outcome. Bioccipital lucencies were found in computed tomographic (CT) scans of 14 patients; none of the 14 regained good vision. Recovery of vision was poor in all 8 patients who had a spontaneous stroke, but fair or good in 11 of the other 17 patients. Prognosis was best in patients under the age of 40 years, in those without a history of hypertension or diabetes mellitus, and in those without associated cognitive, language, or memory impair- ments. We conclude that (1) the prognosis in cortical blindness is poor when caused by stroke; (2) EEGs are more useful than visual evoked potentials for diagnosis; and (3) bioccipital abnormalities shown on CT scan are associated with a poor prognosis. Aldrich MS, Alessi AG, Beck RW, Gilman S: Cortical blindness: etiology, diagnosis, and prognosis. -
Preventable Diseases Nick Wilson, Michael G Baker Abstract New Zealanders Can Now Reflect on and Celebrate 50 Years of Polio Elimination in This Country
THE NEW ZEALAND MEDICAL JOURNAL Journal of the New Zealand Medical Association Celebrating 50 years of polio elimination in New Zealand: but inadequate progress in eliminating other vaccine- preventable diseases Nick Wilson, Michael G Baker Abstract New Zealanders can now reflect on and celebrate 50 years of polio elimination in this country. This success was followed by eliminating two other infectious diseases, brucellosis and hydatids, and an imported potential disease vector, the southern saltmarsh mosquito. However, this country has made inadequate progress in eliminating several other vaccine-preventable diseases. These include measles, mumps, and rubella, which are priority candidates for elimination, and potentially Hib disease and rotavirus infection. To achieve such successes almost certainly requires that the country: (i) builds national leadership for elimination goals; (ii) develops detailed plans; (iii) continues recent successes in enhancing routine vaccination coverage; (iv) introduces rotavirus vaccine into the childhood immunisation schedule; and (v) strengthens surveillance and research (on such questions as the cost-effectiveness of new vaccines, measures to enhance uptake, and effective border controls to reduce the risk of disease importation). For 50 years now (since 1 April 1962), New Zealand has been free of transmission of wild-type polio virus infection. The end of this disease was particularly sudden with cases declining from 214 notifications in an outbreak in 1961 (with seven deaths) to only five cases in early 1962. 1 The end coincided with mass immunisation campaigns with the new Sabin (oral) vaccine in 1961 and 1962. The coverage in the vaccination campaign running from April to June 1962 was approximately 95% of the child population up to school leaving age. -
Bilateral Cortical Blindness Due to Bilateral Occipital Infarcts Without Anosognosia
Journal of Neurology & Stroke Bilateral Cortical Blindness due to Bilateral Occipital Infarcts without Anosognosia Abstract Case Report Bilateral cortical blindness refers to the total loss of vision in the presence of Volume 4 Issue 1- 2016 normal pupillary reflexes and in the absence of Ophthalmological disease resulting from bilateral lesions of the striate cortex in the occipital lobes. In most cases, these patients deny their blindness and their behavior is as if they have an intact vision. We report the case of an 84-year-old man with bilateral cortical blindness resulting from bilateral occipital lobe infarcts. The patient presented this infrequent clinical condition after acute bilateral infarction of the occipital 1First Propedeutic Department of Internal Medicine, lobes possibly due to cardiac embolism resulting from atrial fibrillation of Aristotle University of Thessaloniki, Greece unknown duration. Subcutaneous administration of low molecular weight heparin 2First Department of Neurology, Aristotle University of in therapeutic doses resulted in neurological improvement in the first four days. Thessaloniki, Greece Interestingly, the visual symptoms were complicated neither by anosognosia 3First Department of Ophthalmology, Aristotle University of nor by memory impairment. Cortical blindness and Anton’s syndrome should Thessaloniki, Greece be considered in patients with atypical visual loss and evidence of occipital lobe 4Department of Radiology, Aristotle University of injury. Cerebrovascular disease could be the background -
THE CLINICAL ASSESSMENT of the PATIENT with EARLY DEMENTIA S Cooper, J D W Greene V15
J Neurol Neurosurg Psychiatry: first published as 10.1136/jnnp.2005.081133 on 16 November 2005. Downloaded from THE CLINICAL ASSESSMENT OF THE PATIENT WITH EARLY DEMENTIA S Cooper, J D W Greene v15 J Neurol Neurosurg Psychiatry 2005;76(Suppl V):v15–v24. doi: 10.1136/jnnp.2005.081133 ementia is a clinical state characterised by a loss of function in at least two cognitive domains. When making a diagnosis of dementia, features to look for include memory Dimpairment and at least one of the following: aphasia, apraxia, agnosia and/or disturbances in executive functioning. To be significant the impairments should be severe enough to cause problems with social and occupational functioning and the decline must have occurred from a previously higher level. It is important to exclude delirium when considering such a diagnosis. When approaching the patient with a possible dementia, taking a careful history is paramount. Clues to the nature and aetiology of the disorder are often found following careful consultation with the patient and carer. A focused cognitive and physical examination is useful and the presence of specific features may aid in diagnosis. Certain investigations are mandatory and additional tests are recommended if the history and examination indicate particular aetiologies. It is useful when assessing a patient with cognitive impairment in the clinic to consider the following straightforward questions: c Is the patient demented? c If so, does the loss of function conform to a characteristic pattern? c Does the pattern of dementia conform to a particular pattern? c What is the likely disease process responsible for the dementia? An understanding of cognitive function and its anatomical correlates is necessary in order to ascertain which brain areas are affected. -
Patients with Cortical Blindness Who Do Not Have Any Residual Functional Vision, Talking Devices Can Be Given, I.E
Title: Reading Ability spared in a case of Acquired Cortical Blindness, Neuroplasticity or Left posterior occipitotemporal sulcus sparing? Authors: Kim Ly, OD, Andrea L. Murphy, OD, FAAO Dorothy L. Hitchmoth, OD, FAAO, ABO, ABCMO Abstract: A patient with complete cortical blindness, as a result of sequential, bilateral occipital strokes, is able to read with occasional accuracy despite no evidence of macular field sparing and no light perception bilaterally. Case History Patient Demographics and Social History: o 58 year-old white male presents to his visit: . Accompanied by his ex-wife . Using sighted guide and a rolling walker for ambulation . Reporting he is in the process of moving in with his son for full-time caregiver support, previously homeless Chief Complaint o Primary complaint of loss of vision: . Started about 1 year ago after a “stroke” . Patient reports loss of vision following: the left half of his visual field in his left eye and "less than one half" in his right eye . A second stroke two months ago caused “complete blindness” . Patient and ex-wife report that patient can still read on occasion, i.e. directions on their car's GPS system or brochures o Secondary Complaint: . Gritty eyes that burn throughout the day Ocular History o Blindness OU o Patient did not report any other ocular history Medical History o Cerebrovascular accident (CVA) of the right occipital lobe secondary to cardiac embolus formation as a result of atrial fibrillation 10/2015 o Cerebrovascular accident affecting the left occipital lobe 6/2016 -
LIST of OCCUPATIONAL DISEASES (Revised 2010)
LIST OF OCCUPATIONAL DISEASES (revised 2010) Identification and recognition of occupational diseases: Criteria for incorporating diseases in the ILO list of occupational diseases Occupational Safety and Health Series, No. 74 List of occupational diseases (revised 2010) Identification and recognition of occupational diseases: Criteria for incorporating diseases in the ILO list of occupational diseases INTERNATIONAL LABOUR OFFICE • GENEVA Copyright © International Labour Organization 2010 First published 2010 Publications of the International Labour Office enjoy copyright under Protocol 2 of the Universal Copyright Convention. Nevertheless, short excerpts from them may be reproduced without authorization, on condition that the source is indicated. For rights of reproduction or translation, application should be made to ILO Publications (Rights and Permissions), International Labour Office, CH-1211 Geneva 22, Switzerland, or by email: pubdroit@ ilo.org. The International Labour Office welcomes such applications. Libraries, institutions and other users registered with reproduction rights organizations may make copies in accordance with the licences issued to them for this purpose. Visit www.ifrro.org to find the reproduction rights organization in your country. ILO List of occupational diseases (revised 2010). Identification and recognition of occupational diseases: Criteria for incorporating diseases in the ILO list of occupational diseases Geneva, International Labour Office, 2010 (Occupational Safety and Health Series, No. 74) occupational disease / definition. 13.04.3 ISBN 978-92-2-123795-2 ISSN 0078-3129 Also available in French: Liste des maladies professionnelles (révisée en 2010): Identification et reconnaissance des maladies professionnelles: critères pour incorporer des maladies dans la liste des maladies professionnelles de l’OIT (ISBN 978-92-2-223795-1, ISSN 0250-412x), Geneva, 2010, and in Spanish: Lista de enfermedades profesionales (revisada en 2010). -
ICD-10 International Statistical Classification of Diseases and Related Health Problems
ICD-10 International Statistical Classification of Diseases and Related Health Problems 10th Revision Volume 2 Instruction manual 2010 Edition WHO Library Cataloguing-in-Publication Data International statistical classification of diseases and related health problems. - 10th revision, edition 2010. 3 v. Contents: v. 1. Tabular list – v. 2. Instruction manual – v. 3. Alphabetical index. 1.Diseases - classification. 2.Classification. 3.Manuals. I.World Health Organization. II.ICD-10. ISBN 978 92 4 154834 2 (NLM classification: WB 15) © World Health Organization 2011 All rights reserved. Publications of the World Health Organization are available on the WHO web site (www.who.int) or can be purchased from WHO Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland (tel.: +41 22 791 3264; fax: +41 22 791 4857; e-mail: [email protected]). Requests for permission to reproduce or translate WHO publications – whether for sale or for noncommercial distribution – should be addressed to WHO Press through the WHO web site (http://www.who.int/about/licensing/copyright_form). The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. -
Diseases of the Canine Digit
Diseases of the Canine Digit Diseases of the digit are relatively common and are particularly frustrating in terms of therapy. Unlike many other areas of skin, persisting diseases of the digit will almost always require biopsy to distinguish among a very long list of radically different etiologic possibilities. One cannot tell, just by looking at it, whether the digital swelling is chronic inflammation or squamous cell carcinoma, or whether the lump on the side of the digit is a harmless plasmacytoma or a potentially fatal amelanotic malignant melanoma. 1. Multiple nails that are brittle, deformed, or fall out: Most textbooks will provide a very long list of diseases of the nail and nail bed, but in practical terms I see only one syndrome: lupoid onychodystrophy. Bacterial and fungal paronychia, for example, is so rare in my collection that I have some skepticism that it even exists! The syndrome of lupoid onychodystrophy is seen in young mature dogs (1-5 years), and these animals present with a complaint of deformed nails that are periodically lost. The disease affects multiple digits on multiple feet, often eventually affecting all nails on all feet. The lesion is a lupus-like destructive disease (lymphocytic interface dermatitis with single cell necrosis) of the basal cells of the nail bed epithelium. As is true with similar histologic reactions affecting the nasal planum, gingiva, or conjunctiva, it is not yet clear whether this highly repeatable histologic pattern is really a reflection of a single disease, or is simply the way that the nail bed epithelium responds to a variety of different injuries. -
FAQ REGARDING DISEASE REPORTING in MONTANA | Rev
Disease Reporting in Montana: Frequently Asked Questions Title 50 Section 1-202 of the Montana Code Annotated (MCA) outlines the general powers and duties of the Montana Department of Public Health & Human Services (DPHHS). The three primary duties that serve as the foundation for disease reporting in Montana state that DPHHS shall: • Study conditions affecting the citizens of the state by making use of birth, death, and sickness records; • Make investigations, disseminate information, and make recommendations for control of diseases and improvement of public health to persons, groups, or the public; and • Adopt and enforce rules regarding the reporting and control of communicable diseases. In order to meet these obligations, DPHHS works closely with local health jurisdictions to collect and analyze disease reports. Although anyone may report a case of communicable disease, such reports are submitted primarily by health care providers and laboratories. The Administrative Rules of Montana (ARM), Title 37, Chapter 114, Communicable Disease Control, outline the rules for communicable disease control, including disease reporting. Communicable disease surveillance is defined as the ongoing collection, analysis, interpretation, and dissemination of disease data. Accurate and timely disease reporting is the foundation of an effective surveillance program, which is key to applying effective public health interventions to mitigate the impact of disease. What diseases are reportable? A list of reportable diseases is maintained in ARM 37.114.203. The list continues to evolve and is consistent with the Council of State and Territorial Epidemiologists (CSTE) list of Nationally Notifiable Diseases maintained by the Centers for Disease Control and Prevention (CDC). In addition to the named conditions on the list, any occurrence of a case/cases of communicable disease in the 20th edition of the Control of Communicable Diseases Manual with a frequency in excess of normal expectancy or any unusual incident of unexplained illness or death in a human or animal should be reported.