Design of Basic Logic Gates Using NAND Gate
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Engineering Transcriptional Control and Synthetic Gene Circuits in Cell Free Systems
University of Tennessee, Knoxville TRACE: Tennessee Research and Creative Exchange Doctoral Dissertations Graduate School 12-2012 Engineering Transcriptional Control and Synthetic Gene Circuits in Cell Free systems Sukanya Iyer University of Tennessee, [email protected] Follow this and additional works at: https://trace.tennessee.edu/utk_graddiss Part of the Biotechnology Commons Recommended Citation Iyer, Sukanya, "Engineering Transcriptional Control and Synthetic Gene Circuits in Cell Free systems. " PhD diss., University of Tennessee, 2012. https://trace.tennessee.edu/utk_graddiss/1586 This Dissertation is brought to you for free and open access by the Graduate School at TRACE: Tennessee Research and Creative Exchange. It has been accepted for inclusion in Doctoral Dissertations by an authorized administrator of TRACE: Tennessee Research and Creative Exchange. For more information, please contact [email protected]. To the Graduate Council: I am submitting herewith a dissertation written by Sukanya Iyer entitled "Engineering Transcriptional Control and Synthetic Gene Circuits in Cell Free systems." I have examined the final electronic copy of this dissertation for form and content and recommend that it be accepted in partial fulfillment of the equirr ements for the degree of Doctor of Philosophy, with a major in Life Sciences. Mitchel J. Doktycz, Major Professor We have read this dissertation and recommend its acceptance: Michael L. Simpson, Albrecht G. von Arnim, Barry D. Bruce, Jennifer L. Morrell-Falvey Accepted for the Council: Carolyn R. Hodges Vice Provost and Dean of the Graduate School (Original signatures are on file with official studentecor r ds.) Engineering Transcriptional Control and Synthetic Gene Circuits in Cell Free systems A Dissertation Presented for the Doctor of Philosophy Degree The University of Tennessee, Knoxville Sukanya Iyer December 2012 Copyright © 2012 by Sukanya Iyer. -
CSE Yet, Please Do Well! Logical Connectives
administrivia Course web: http://www.cs.washington.edu/311 Office hours: 12 office hours each week Me/James: MW 10:30-11:30/2:30-3:30pm or by appointment TA Section: Start next week Call me: Shayan Don’t: Actually call me. Homework #1: Will be posted today, due next Friday by midnight (Oct 9th) Gradescope! (stay tuned) Extra credit: Not required to get a 4.0. Counts separately. In total, may raise grade by ~0.1 Don’t be shy (raise your hand in the back)! Do space out your participation. If you are not CSE yet, please do well! logical connectives p q p q p p T T T T F T F F F T F T F NOT F F F AND p q p q p q p q T T T T T F T F T T F T F T T F T T F F F F F F OR XOR 푝 → 푞 • “If p, then q” is a promise: p q p q F F T • Whenever p is true, then q is true F T T • Ask “has the promise been broken” T F F T T T If it’s raining, then I have my umbrella. related implications • Implication: p q • Converse: q p • Contrapositive: q p • Inverse: p q How do these relate to each other? How to see this? 푝 ↔ 푞 • p iff q • p is equivalent to q • p implies q and q implies p p q p q Let’s think about fruits A fruit is an apple only if it is either red or green and a fruit is not red and green. -
Transistors and Logic Gates
Introduction to Computer Engineering CS/ECE 252, Spring 2013 Prof. Mark D. Hill Computer Sciences Department University of Wisconsin – Madison Chapter 3 Digital Logic Structures Slides based on set prepared by Gregory T. Byrd, North Carolina State University Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Transistor: Building Block of Computers Microprocessors contain millions of transistors • Intel Pentium II: 7 million • Compaq Alpha 21264: 15 million • Intel Pentium III: 28 million Logically, each transistor acts as a switch Combined to implement logic functions • AND, OR, NOT Combined to build higher-level structures • Adder, multiplexer, decoder, register, … Combined to build processor • LC-3 3-3 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Simple Switch Circuit Switch open: • No current through circuit • Light is off • Vout is +2.9V Switch closed: • Short circuit across switch • Current flows • Light is on • Vout is 0V Switch-based circuits can easily represent two states: on/off, open/closed, voltage/no voltage. 3-4 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. N-type MOS Transistor MOS = Metal Oxide Semiconductor • two types: N-type and P-type N-type • when Gate has positive voltage, short circuit between #1 and #2 (switch closed) • when Gate has zero voltage, open circuit between #1 and #2 Gate = 1 (switch open) Gate = 0 Terminal #2 must be connected to GND (0V). 3-5 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. P-type MOS Transistor P-type is complementary to N-type • when Gate has positive voltage, open circuit between #1 and #2 (switch open) • when Gate has zero voltage, short circuit between #1 and #2 (switch closed) Gate = 1 Gate = 0 Terminal #1 must be connected to +2.9V. -
Universal Gate - NAND Digital Electronics 2.2 Intro to NAND & NOR Logic
Universal Gate - NAND Digital Electronics 2.2 Intro to NAND & NOR Logic Universal Gate – NAND This presentation will demonstrate • The basic function of the NAND gate. • How a NAND gate can be used to replace an AND gate, an OR gate, or an INVERTER gate. • How a logic circuit implemented with AOI logic gates can Universal Gate – NAND be re-implemented using only NAND gates. • That using a single gate type, in this case NAND, will reduce the number of integrated circuits (IC) required to implement a logic circuit. Digital Electronics AOI Logic NAND Logic 2 More ICs = More $$ Less ICs = Less $$ NAND Gate NAND Gate as an Inverter Gate X X X (Before Bubble) X Z X Y X Y X Z X Y X Y Z X Z 0 0 1 0 1 Equivalent to Inverter 0 1 1 1 0 1 0 1 1 1 0 3 4 Project Lead The Way, Inc Copyright 2009 1 Universal Gate - NAND Digital Electronics 2.2 Intro to NAND & NOR Logic NAND Gate as an AND Gate NAND Gate as an OR Gate X X Y Y X X Z X Y X Y Y Z X Y X Y X Y Y NAND Gate Inverter Inverters NAND Gate X Y Z X Y Z 0 0 0 0 0 0 0 1 0 0 1 1 Equivalent to AND Gate Equivalent to OR Gate 1 0 0 1 0 1 1 1 1 1 1 1 5 6 NAND Gate Equivalent to AOI Gates Process for NAND Implementation 1. -
Digital IC Listing
BELS Digital IC Report Package BELS Unit PartName Type Location ID # Price Type CMOS 74HC00, Quad 2-Input NAND Gate DIP-14 3 - A 500 0.24 74HCT00, Quad 2-Input NAND Gate DIP-14 3 - A 501 0.36 74HC02, Quad 2 Input NOR DIP-14 3 - A 417 0.24 74HC04, Hex Inverter, buffered DIP-14 3 - A 418 0.24 74HC04, Hex Inverter (buffered) DIP-14 3 - A 511 0.24 74HCT04, Hex Inverter (Open Collector) DIP-14 3 - A 512 0.36 74HC08, Quad 2 Input AND Gate DIP-14 3 - A 408 0.24 74HC10, Triple 3-Input NAND DIP-14 3 - A 419 0.31 74HC32, Quad OR DIP-14 3 - B 409 0.24 74HC32, Quad 2-Input OR Gates DIP-14 3 - B 543 0.24 74HC138, 3-line to 8-line decoder / demultiplexer DIP-16 3 - C 603 1.05 74HCT139, Dual 2-line to 4-line decoders / demultiplexers DIP-16 3 - C 605 0.86 74HC154, 4-16 line decoder/demulitplexer, 0.3 wide DIP - Small none 445 1.49 74HC154W, 4-16 line decoder/demultiplexer, 0.6wide DIP none 446 1.86 74HC190, Synchronous 4-Bit Up/Down Decade and Binary Counters DIP-16 3 - D 637 74HCT240, Octal Buffers and Line Drivers w/ 3-State outputs DIP-20 3 - D 643 1.04 74HC244, Octal Buffers And Line Drivers w/ 3-State outputs DIP-20 3 - D 647 1.43 74HCT245, Octal Bus Transceivers w/ 3-State outputs DIP-20 3 - D 649 1.13 74HCT273, Octal D-Type Flip-Flops w/ Clear DIP-20 3 - D 658 1.35 74HCT373, Octal Transparent D-Type Latches w/ 3-State outputs DIP-20 3 - E 666 1.35 74HCT377, Octal D-Type Flip-Flops w/ Clock Enable DIP-20 3 - E 669 1.50 74HCT573, Octal Transparent D-Type Latches w/ 3-State outputs DIP-20 3 - E 674 0.88 Type CMOS CD4000 Series CD4001, Quad 2-input -
The Equation for the 3-Input XOR Gate Is Derived As Follows
The equation for the 3-input XOR gate is derived as follows The last four product terms in the above derivation are the four 1-minterms in the 3-input XOR truth table. For 3 or more inputs, the XOR gate has a value of 1when there is an odd number of 1’s in the inputs, otherwise, it is a 0. Notice also that the truth tables for the 3-input XOR and XNOR gates are identical. It turns out that for an even number of inputs, XOR is the inverse of XNOR, but for an odd number of inputs, XOR is equal to XNOR. All these gates can be interconnected together to form large complex circuits which we call networks. These networks can be described graphically using circuit diagrams, with Boolean expressions or with truth tables. 3.2 Describing Logic Circuits Algebraically Any logic circuit, no matter how complex, may be completely described using the Boolean operations previously defined, because of the OR gate, AND gate, and NOT circuit are the basic building blocks of digital systems. For example consider the circuit shown in Figure 1.3(c). The circuit has three inputs, A, B, and C, and a single output, x. Utilizing the Boolean expression for each gate, we can easily determine the expression for the output. The expression for the AND gate output is written A B. This AND output is connected as an input to the OR gate along with C, another input. The OR gate operates on its inputs such that its output is the OR sum of the inputs. -
Static CMOS Circuits
Static CMOS Circuits • Conventional (ratio-less) static CMOS – Covered so far • Ratio-ed logic (depletion load, pseudo nMOS) • Pass transistor logic ECE 261 Krish Chakrabarty 1 Example 1 module mux(input s, d0, d1, output y); assign y = s ? d1 : d0; endmodule 1) Sketch a design using AND, OR, and NOT gates. ECE 261 Krish Chakrabarty 2 1 Example 1 module mux(input s, d0, d1, output y); assign y = s ? d1 : d0; endmodule 1) Sketch a design using AND, OR, and NOT gates. ECE 261 Krish Chakrabarty 3 Example 2 2) Sketch a design using NAND, NOR, and NOT gates. Assume ~S is available. ECE 261 Krish Chakrabarty 4 2 Example 2 2) Sketch a design using NAND, NOR, and NOT gates. Assume ~S is available. ECE 261 Krish Chakrabarty 5 Bubble Pushing • Start with network of AND / OR gates • Convert to NAND / NOR + inverters • Push bubbles around to simplify logic – Remember DeMorgan’s Law ECE 261 Krish Chakrabarty 6 3 Example 3 3) Sketch a design using one compound gate and one NOT gate. Assume ~S is available. ECE 261 Krish Chakrabarty 7 Example 3 3) Sketch a design using one compound gate and one NOT gate. Assume ~S is available. ECE 261 Krish Chakrabarty 8 4 Compound Gates • Logical Effort of compound gates ECE 261 Krish Chakrabarty 9 Example 4 • The multiplexer has a maximum input capacitance of 16 units on each input. It must drive a load of 160 units. Estimate the delay of the NAND and compound gate designs. H = 160 / 16 = 10 B = 1 N = 2 ECE 261 Krish Chakrabarty 10 5 NAND Solution ECE 261 Krish Chakrabarty 11 NAND Solution ECE 261 Krish Chakrabarty 12 6 Compound Solution ECE 261 Krish Chakrabarty 13 Compound Solution ECE 261 Krish Chakrabarty 14 7 Example 5 • Annotate your designs with transistor sizes that achieve this delay. -
Design a 3-Input CMOS NAND Gate (PUN/PDN) with Fan-Out of 3. Total Output Load of the NAND Gate Is Equal to 15Ff and Μn/Μp = 2.5
Tutorial on Transistor Sizing Problem #1 (Static CMOS logic): Design a 3-input CMOS NAND gate (PUN/PDN) with fan-out of 3. Total output load of the NAND gate is equal to 15fF and µn/µp = 2.5. For 0.35µm process technology tox = -9 -12 7.6*10 m, εox = 35*10 F/m. Compare the above design with that of a 3-input NOR (PUN/PDN) gate. State any benefits of one implementation over the other. For the sake of simplicity assume all capacitance is lumped and gate capacitance neglecting diffusion and wiring capacitance. Solution: Cox = εoxWL/ tox = 15fF. So W = 9.2µm. Leff = 0.35µm. Assuming output load is all gate capacitance. This is a simplifying assumption made for this problem. A more realistic approach would be to calculate the diffusion and wiring capacitances as well. Equivalent inverter for fan-out of 3 and µn/µp = 2.5 would result in: A B C 2.23 2.23 2.23 Wp = 2.5*Wn for equal rise and fall times. Also, Wp + Wn = 9.2/3 = 3.16µm for fan-out of 3. A 2.67 B Solving the above equations we have, 2.67 C 2.67 Wp = 2.23µm and Wn = 0.89µm. NAND implementation: NAND implementation Therefore, for the 3-ip NAND gate implementation, each PDN n-MOS transistor will be: 3*0.89µm = 2.67µm A and each p-MOS transistor in the PUN network will be: 2.23µm 6.69 B NOR implementation: 6.69 For a 3-ip NOR gate implementation, each PDN n-MOS transistor C will be: 0.89µm 6.69 A BC Each PUN p-MOS transistor will be 3*2.23µm = 6.69µm 0.89 0.89 0.89 Area comparison: NOR implementation Total gate area of NAND gate is: 3*(2.67+2.23)µm = 14.7µm Total gate area of NOR gate is: 3*(6.69+0.89) µm = 22.7µm Thus we infer that the NAND gate has less area and power compared to the NOR gate for identical loading and fan-out conditions and is the preferred implementation. -
Hardware Abstract the Logic Gates References Results Transistors Through the Years Acknowledgements
The Practical Applications of Logic Gates in Computer Science Courses Presenters: Arash Mahmoudian, Ashley Moser Sponsored by Prof. Heda Samimi ABSTRACT THE LOGIC GATES Logic gates are binary operators used to simulate electronic gates for design of circuits virtually before building them with-real components. These gates are used as an instrumental foundation for digital computers; They help the user control a computer or similar device by controlling the decision making for the hardware. A gate takes in OR GATE AND GATE NOT GATE an input, then it produces an algorithm as to how The OR gate is a logic gate with at least two An AND gate is a consists of at least two A NOT gate, also known as an inverter, has to handle the output. This process prevents the inputs and only one output that performs what inputs and one output that performs what is just a single input with rather simple behavior. user from having to include a microprocessor for is known as logical disjunction, meaning that known as logical conjunction, meaning that A NOT gate performs what is known as logical negation, which means that if its input is true, decision this making. Six of the logic gates used the output of this gate is true when any of its the output of this gate is false if one or more of inputs are true. If all the inputs are false, the an AND gate's inputs are false. Otherwise, if then the output will be false. Likewise, are: the OR gate, AND gate, NOT gate, XOR gate, output of the gate will also be false. -
Chapter 6 - Combinational Logic Systems GCSE Electronics – Component 1: Discovering Electronics
Chapter 6 - Combinational logic systems GCSE Electronics – Component 1: Discovering Electronics Combinational logic systems Learners should be able to: (a) recognise 1/0 as two-state logic levels (b) identify and use NOT gates and 2-input AND, OR, NAND and NOR gates, singly and in combination (c) produce a suitable truth table from a given system specification and for a given logic circuit (d) use truth tables to analyse a system of gates (e) use Boolean algebra to represent the output of truth tables or logic gates and use the basic Boolean identities A.B = A+B and A+B = A.B (f) design processing systems consisting of logic gates to solve problems (g) simplify logic circuits using NAND gate redundancy (h) analyse and design systems from a given truth table to solve a given problem (i) use data sheets to select a logic IC for given applications and to identify pin connections (j) design and use switches and pull-up or pull-down resistors to provide correct logic level/edge-triggered signals for logic gates and timing circuits 180 © WJEC 2017 Chapter 6 - Combinational logic systems GCSE Electronics – Component 1: Discovering Electronics Introduction In this chapter we will be concentrating on the basics of digital logic circuits which will then be extended in Component 2. We should start by ensuring that you understand the difference between a digital signal and an analogue signal. An analogue signal Voltage (V) Max This is a signal that can have any value between the zero and maximum of the power supply. Changes between values can occur slowly or rapidly depending on the system involved. -
Solving Logic Problems with a Twist
Transformations Volume 6 Issue 1 Winter 2020 Article 6 11-30-2020 Solving Logic Problems with a Twist Angie Su Nova Southeastern University, [email protected] Bhagi Phuel Chloe Johnson Dylan Mandolini Shawlyn Fleming Follow this and additional works at: https://nsuworks.nova.edu/transformations Part of the Science and Mathematics Education Commons, and the Teacher Education and Professional Development Commons Recommended Citation Su, Angie; Bhagi Phuel; Chloe Johnson; Dylan Mandolini; and Shawlyn Fleming (2020) "Solving Logic Problems with a Twist," Transformations: Vol. 6 : Iss. 1 , Article 6. Available at: https://nsuworks.nova.edu/transformations/vol6/iss1/6 This Article is brought to you for free and open access by the Abraham S. Fischler College of Education at NSUWorks. It has been accepted for inclusion in Transformations by an authorized editor of NSUWorks. For more information, please contact [email protected]. Solving Logic Problems with a Twist Cover Page Footnote This article was originally published in the Dimensions Journal, A publication of the Florida Council of Teachers of Mathematics Journal. This article is available in Transformations: https://nsuworks.nova.edu/transformations/vol6/iss1/6 Su, Hui Fang Huang, Bhagi Phuel, Chloe Johnson, Dylan Mandolini, and Shawlyn Fleming Solving Logic Problems with a Twist Solving Logic Problems with a Twist Hui Fang Huang Su, Bhagi Phuel, Chloe Johnson, Dylan Mandolini, and Shawlyn Fleming Review of Symbolic Logic Aristotle, Greek philosopher and scientist, was a pupil of Plato and asserted that any logical argument is reducible to two premises and a conclusion (Gullberg, 1997). According to classical (Aristotelian) logic, arguments are governed by three fundamental laws: the principle of identity, the principle of the excluded middle, and the principle of contradiction. -
Designing Combinational Logic Gates in Cmos
CHAPTER 6 DESIGNING COMBINATIONAL LOGIC GATES IN CMOS In-depth discussion of logic families in CMOS—static and dynamic, pass-transistor, nonra- tioed and ratioed logic n Optimizing a logic gate for area, speed, energy, or robustness n Low-power and high-performance circuit-design techniques 6.1 Introduction 6.3.2 Speed and Power Dissipation of Dynamic Logic 6.2 Static CMOS Design 6.3.3 Issues in Dynamic Design 6.2.1 Complementary CMOS 6.3.4 Cascading Dynamic Gates 6.5 Leakage in Low Voltage Systems 6.2.2 Ratioed Logic 6.4 Perspective: How to Choose a Logic Style 6.2.3 Pass-Transistor Logic 6.6 Summary 6.3 Dynamic CMOS Design 6.7 To Probe Further 6.3.1 Dynamic Logic: Basic Principles 6.8 Exercises and Design Problems 197 198 DESIGNING COMBINATIONAL LOGIC GATES IN CMOS Chapter 6 6.1Introduction The design considerations for a simple inverter circuit were presented in the previous chapter. In this chapter, the design of the inverter will be extended to address the synthesis of arbitrary digital gates such as NOR, NAND and XOR. The focus will be on combina- tional logic (or non-regenerative) circuits that have the property that at any point in time, the output of the circuit is related to its current input signals by some Boolean expression (assuming that the transients through the logic gates have settled). No intentional connec- tion between outputs and inputs is present. In another class of circuits, known as sequential or regenerative circuits —to be dis- cussed in a later chapter—, the output is not only a function of the current input data, but also of previous values of the input signals (Figure 6.1).