DOCSLIB.ORG

Table of Common Heart Medications

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Table of Common Heart Medications Table of Common Cardiac Medications Only your healthcare providers can tell you the exact purpose of your specific prescriptions. However, it’s likely that your medications fall into the categories described in the table below. Use this table as a reference to help you learn more about the medication you’re taking. MEDICATION CATEGORIES EXAMPLES* SIDE EFFECTS AND NOTES ACE inhibitors ACE inhibitors: Side effect: (angiotensin • benazepril (Lotensin) A dry, non-productive cough is converting enzyme • captopril (Capoten) a common side effect of ACE inhibitors) inhibitors. • enalapril maleate (Vasotec) OR • lisinopril (Prinivil, Zestril) Note: ARBs • quinapril (Accupril) Don’t use potassium supplements (angiotensin II receptor or salt substitutes without first • ramipril (Altace) antagonists) asking your healthcare providers. These medications block stress ARBs: hormones and relieve stress on the heart’s pumping action. • candesartan cilexetil (Atacand) They improve symptoms and • eprosartan mesylate (Teveten) reduce hospitalizations • irbesartan (Avapro) for patients with heart failure. • losartan (Cozaar) • telmisartan (Micardis) • valsartan (Diovan) Antiarrhythmics • amiodarone (Cordarone) Notes: (heart rhythm • disopyramide phosphate (Norpace) • As with any medication, take medications) • dofetilide (Tikosyn) antiarrhythmics exactly as ordered. These control irregular • flecainide (Tambocor) • If you’re taking some of these heartbeats — and maintain a • mexiletine HCl (Mexitil) medications, you’ll need ongoing normal heart rate and rhythm. monitoring by your healthcare • procainamide (Procan, Pronestyl) provider. • propafenone HCl (Rythmol) • If you’re taking an extended-release • propafenone HCI SR (Rythmol SR) tablet, be sure to swallow the pill • quinadine glucomate (Quinaglute) whole — don’t break, chew, or • sotalol (Betapace, see beta blockers) crush it. • tocainide HCl (Tonocard) *Generic drug names are listed in lowercase letters. 100 MEDICATION MEDICATION CATEGORIES EXAMPLES* SIDE EFFECTS AND NOTES Anticoagulants and Anticoagulants: Side effect: platelet inhibitors • dalteparin sodium (Fragmin) Call your healthcare provider if you notice bleeding (“blood thinners”) • enoxaparin (Lovenox) from your gums, or blood in your urine or stools. These cause your blood to • fondaparinux (Arixtra) Notes: take longer to clot, which can • heparin sodium • Make sure your provider knows about all other reduce the risk of strokes and • warfarin (Coumadin) medication you’re using. Many substances — heart attacks that can occur including over-the-counter drugs and herbal when blood clots get stuck in Platelet inhibitors: supplements — should not be used while you’re small blood vessels. • aspirin taking some blood thinners. • cilostazol (Pletal) • If you’re taking some of these medications, you’ll need • clopidogril bisulfate (Plavix) ongoing monitoring by your healthcare provider. • dipyramidamole (Persantine) • If you miss a dose, do NOT take extra the next time to “catch up.” • prasugrel (Effient) • Be consistent with your diet, especially foods rich • ticlopidine (Ticlid) in vitamin K (see chapter 8). • Keep regular appointments to have your blood tested to make sure it’s clotting at the right level. Depending on the type of test, it’s called a PT (or PT/INR) or a PTT test. Antihypertensives • clonidine HCl (Catapres, Dixarit) Note: (blood pressure medication) • doxazosin mesylate (Cardura) As with any drug, don’t stop using blood These are commonly used to • hydralazine HCI pressure medication without first asking your treat high blood pressure by • methyldopa (Aldomet) healthcare provider. relaxing and widening • minoxidil blood vessels. • phenoxybenzamine HCl (Dibenzyline) • phentolamine mesylate (Regitine) • prazosin HCl (Minipress) • terazosin HCl (Hytrin) Beta blockers • acebutolol HCl (Sectral) Side effects: These medications are often • atenolol (Tenormin) • In some people, beta blockers can cause drowsiness. prescribed to treat angina, high • betaxolol (Kerlone) • Call your healthcare provider right away blood pressure, and irregular • bisoprolol (Zebeta) if you have any of these side effects: heart rhythms. They: • carvedilol (Coreg) – Chest pain (may be related to your disease • Block stress hormones and • labetalol HCl (Normodyne, Trandate) and not a side effect) relieve stress on the heart’s • metoprolol succinate (Toprol XL) – Fainting or severe dizziness pumping action • metoprolol tartrate (Lopressor) – Slow, fast, or irregular heartbeat • Relax the blood vessels so – Swelling of your feet or ankles blood can move more easily • nadolol (Corgard) • nebivolol (Bystolic) – Unusual bleeding or bruising • Improve the heart’s function • pindolol (Visken) – Unusual weight gain • Reduce symptoms and lessen the chance of future • propranolol HCl (Inderal) – Wheezing or trouble breathing hospitalizations • sotalol (Betapace) • timolol maleate (Blocadren) *Generic drug names are listed in lowercase letters. MEDICATION 101 MEDICATION CATEGORIES EXAMPLES* SIDE EFFECTS AND NOTES Calcium channel blockers • amlodipine besylate (Norvasc) Side effect: These are commonly used to treat • bepridil (Vascor) Calcium channel blockers can cause high blood pressure, coronary • diltiazem HCl (Cardizem, Dilacor, Tiazac) swelling in your feet and legs. artery spasms, and angina. They • felodipine (Plendil) restrict the normal flow of calcium • isradipine (DynaCirc) into the cells of the heart and • nicardipine HCl (Cardene) blood vessels, which discourages smaller vessels from narrowing • nifedipine (Adalat, Procardia) and going into spasm, and also • nisoldipine (Sular) reduces the heart’s workload and • verapamil HCl (Calan, Covera, Isoptin) need for oxygen. Digitalis glycosides • digoxin (Lanoxin) Note: These strengthen the heart Many drugs — including some muscle, treat irregular heart antacids and other over-the-counter rhythms, and improve medications — can affect how exercise tolerance. digitalis works in your body. As always, make sure your healthcare provider knows about all the medications and supplements you’re taking. Diuretics (“water pills”) • amiloride (Midamor) Side effects: These help rid your body of excess • bumetanide (Bumex) • Diuretics can cause extreme fluid and salt. They are often • chlorothiazide (Diuril) weight loss, lightheadedness, or prescribed for high blood pressure • ethacrynic acid (Edecrin) increased blood pressure. and congestive heart failure. • furosemide (Lasix) Notes: • hydrochlorothiazide (Esidrix, • Diuretics make you urinate more. HydroDIURIL, Microzide, Oretic) You may want to take diuretics • indapamide (Lozol) early in the morning and/or • metolazone (Mykrox, Zaroxolyn) afternoon. This will help you avoid having to get up at night to urinate. • triamterene (Dyrenium) • Since the use of some diuretics Aldosterone receptor can cause loss of potassium from antagonists the body, potassium supplements • eplerenone (Inspra) are often prescribed with diuretics. • spironolactone (Aldactone) See “potassium supplements” later in this table. Combination products • amiloride and hydrochlorothiazide • spironolactone and hydrochlorothiazide (Aldactazide) • torsemide (Demadex) • triamterene and hydrochlorothiazide (Dyazide, Maxzide) *Generic drug names are listed in lowercase letters. 102 MEDICATION MEDICATION CATEGORIES EXAMPLES* SIDE EFFECTS AND NOTES Lipid medications Statins Side effect: Call your healthcare provider if you have any unexplained muscle (blood cholesterol • atorvastatin calcium (Lipitor) right away pain, weakness, or cramps. lowering agents, • fluvastatin sodium (Lescol) Notes: antihyperlipidemics) • lovastatin (Mevacor) • pravastatin sodium (Pravachol) • The cornerstone of treating high blood The medications in this • rosuvastatin (Crestor) cholesterol is a low-fat, low-cholesterol diet. category work in different • simvastatin (Zocor) Drug therapy only works when you also follow ways. Depending on which dietary guidelines. Fibrates one you’re taking, lipid • With many lipid medications, you can’t eat • fenofibrate (Tricor) medications can lower your grapefruit or drink grapefruit juice. Ask your • gemfibrozil (Lopid) healthcare provider. levels of cholesterol, LDL, and Bile acid sequestrants • Take your statin medication with your evening triglycerides — as well as • colesevelam HCl (Welchol) meal or at bedtime. treat abnormally low levels • cholestyramine (Questran) • If you take fenofibrate (Tricor) AND also take of HDL cholesterol. • colestipol HCl (Colestid) cholestyramine (Questran), colestipol (Colestid), or colesevelam HCl (Welchol) — take your dose Other lipid medications of fenofibrate at least 1 hour before, or 4 to 6 • niacin (Niaspan, Nicolar) hours after, these other medicines. Nitrates and other Nitrates (nitroglycerin) Notes about nitrates: antianginals • oral nitroglycerin (Dilatrate-SR, • If your nitroglycerin pills come with instructions These are commonly used to Imdur, ISMO, Isordil, Monoket) to dissolve them under your tongue, be sure to • nitroglycerin ointment do this. Do NOT swallow them. The drug won’t prevent, reduce, or relieve work if it’s in your stomach. angina pain. They work by (Nitro-Bid Ointment, Nitrol) • Store nitroglycerin in its original bottle, in a relaxing blood vessels and • nitroglycerin skin patches (Deponit, Minitran, Nitro-Dur, dark place. This helps preserve its potency. increasing the supply of blood Transderm-Nitro) • It’s important to replace your nitroglycerin and oxygen to the heart — • nitroglycerin sublingual tablets pills every three
Load more

Recommended publications
  • A Proposal for the Clinical Use of Flecainide
    A Proposal for the Clinical Use of Flecainide JEFFREY L. ANDERSON, MD, JAMES R. STEWART, MD, and BARRY J. CREVEY, MD Effective antiarrhythmic therapy requires a carefully sponse rate is observed in preventing induction of considered approach, including an understanding sustained ventricular tachycardia, and these pa- of the arrhythmia, the underlying cardiac disease tients should be carefully selected. Flecainide is and the drug’s pharmacokinetics. Flecainide is a promising in the treatment of supraventricular new antiarrhythmic drug that may soon be released tachycardias using atrioventricular nodal or extra- for general use. Flecainide demonstrates unsur- nodal reentrant pathways, although this use is still passed efficacy in chronic ventricular arrhythmias investigational in the United States. The drug’s use in stable patients and may become a first-choice for arrhythmias during acute myocardial infarction drug because of its ease of administration, efficacy requires further study. Flecainide possesses modest and favorable tolerance. Twice-daily dosing with negative inotropic potential. Proarrhythmic or other 100 to 200 mg usually provides effective therapy. adverse reactions have occurred primarily in set- Clinical experience suggests flecainide to be indi- tings of high drug level, poor ventricular function cated in the treatment of uniform and multiform or refractory, malignant arrhythmias, suggesting ventricular premature complexes, coupled ven- caution in these groups. tricular premature complexes, and episodes of nonsustained
    [Show full text]
  • Second Generation Antiarrhythmic Agents: Have We Reached Antiarrhythmic Nirvana?
    JACC Vol. 9. NO.2 459 February 1987:459-63 EDITORIAL REVIEWS Second Generation Antiarrhythmic Agents: Have We Reached Antiarrhythmic Nirvana? LEONARD N. HOROWITZ, MD, FACC, JOEL MORGANROTH, MD, FACC Philadelphia, Pennsylvania During the first half of the 20th century, antiarrhythmic some cases novel, but because their preapproval evaluations therapy was principally directed toward supraventricular ar­ followed a more rigorous and circumspect path. More in­ rhythmia; only relatively recently has therapy of ventricular formation is available to us so we can decide when and how arrhythmias been emphasized. In fact, significant pharma­ these agents should be employed. cologic treatment of ventricular arrhythmias was minimal Like all antiarrhythmic drugs of the first generation, the until routine use of quinidine and procainamide began in new agents have the potential to provoke or worsen ven­ the 1950s (1,2). The first generation oral antiarrhythmic tricular arrhythmias. These proarrhythmic effects vary in drugs, quinidine, procainamide and disopyramide, previ­ incidence and may present a major problem in certain patient ously constituted the principal antiarrhythmic agents for long­ groups such as those with sustained ventricular tachyar­ term treatment of ventricular arrhythmias in the United States. rhythrnias, reduced left ventricular function and conduction Compared with modem regulatory standards, the data on disturbances. In common with other antiarrhythmic drugs, which the use of these drugs was based were modest at best the second generation drugs have not been shown to prevent and rudimentary at worst. However, because good clinical sudden death in patients with ventricular ectopic activity. judgment compensates for a multitude of deficiencies, we These factors, along with efficacy and potential toxicity, have been able to provide effective antiarrhythmic therapy must be considered in selecting antiarrhythmic regimens for to many patients with this rather limited pharmacopoeia.
    [Show full text]
  • Ventricular Tachycardia Drugs Versus Devices John Camm St
    Cardiology Update 2015 Davos, Switzerland: 8-12th February 2015 Ventricular Arrhythmias Ventricular Tachycardia Drugs versus Devices John Camm St. George’s University of London, UK Imperial College, London, UK Declaration of Interests Chairman: NICE Guidelines on AF, 2006; ESC Guidelines on Atrial Fibrillation, 2010 and Update, 2012; ACC/AHA/ESC Guidelines on VAs and SCD; 2006; NICE Guidelines on ACS and NSTEMI, 2012; NICE Guidelines on heart failure, 2008; NICE Guidelines on Atrial Fibrillation, 2006; ESC VA and SCD Guidelines, 2015 Steering Committees: multiple trials including novel anticoagulants DSMBs: multiple trials including BEAUTIFUL, SHIFT, SIGNIFY, AVERROES, CASTLE- AF, STAR-AF II, INOVATE, and others Events Committees: one trial of novel oral anticoagulants and multiple trials of miscellaneous agents with CV adverse effects Editorial Role: Editor-in-Chief, EP-Europace and Clinical Cardiology; Editor, European Textbook of Cardiology, European Heart Journal, Electrophysiology of the Heart, and Evidence Based Cardiology Consultant/Advisor/Speaker: Astellas, Astra Zeneca, ChanRX, Gilead, Merck, Menarini, Otsuka, Sanofi, Servier, Xention, Bayer, Boehringer Ingelheim, Bristol- Myers Squibb, Daiichi Sankyo, Pfizer, Boston Scientific, Biotronik, Medtronic, St. Jude Medical, Actelion, GlaxoSmithKline, InfoBionic, Incarda, Johnson and Johnson, Mitsubishi, Novartis, Takeda Therapy for Ventricular Tachycardia Medical therapy Antiarrhythmic drugs Autonomic management Ventricular tachycardia Monomorphic Polymorphic Ventricular fibrillation Ventricular storms Ablation therapy Device therapy Surgical Defibrillation Catheter Antitachycardia pacing History of Antiarrhythmic Drugs 1914 - Quinidine 1950 - Lidocaine 1951 - Procainamide 1946 – Digitalis 1956 – Ajmaline 1962 - Verapamil 1962 – Disopyramide 1964 - Propranolol 1967 – Amiodarone 1965 – Bretylium 1972 – Mexiletine 1973 – Aprindine, Tocainide 1969 - Diltiazem 1975- Flecainide 1976 – Propafenone Encainide Ethmozine 2000 - Sotalol D-sotalol 1995 - Ibutilide (US) Recainam 2000 – Dofetilide US) IndecainideX Etc.
    [Show full text]
  • Draft for Public Comment
    Draft for Public Comment Practice guideline update: Treatment of painful diabetic polyneuropathy Report of the Guideline Subcommittee of the American Academy of Neurology Authors (Alphabetical order—final order to be determined later in the guideline development process) Carmel Armon, MD, MSc, MHS1,Vera Bril, MD2, Brian C. Callaghan, MD, MS3, Lindsay Colbert, MA4, William S. David, MD, PhD5, Mary Dolan O’Brien, MLIS6, Kenneth Fink, MD, MPH7, Gary Franklin, MD, MPH8, Gary Gronseth, MD9, John Halperin, MD10, Lawrence B. Harkless, DPM11, Leslie Levine, PhD, VMD, JD12, Nicole Licking, DO13, Bruce A. Perkins, MD, MPH14, Michael Pignone, MD15, Raymond Price, MD16, Alexander Rae-Grant, MD17, Don Smith, MD18, Scott R. Wessels, MPS, ELS6 1. Department of Neurology, Tel Aviv University Sackler School of Medicine, Israel 2. Division of Neurology, Department of Medicine, Toronto General Hospital, ON, Canada 3. Department of Neurology, University of Michigan, Ann Arbor 4. The Foundation for Peripheral Neuropathy, Buffalo Grove, IL 5. Department of Neurology, Massachusetts General Hospital, Boston 6. American Academy of Neurology, Minneapolis, MN 7. Kamehameha Schools, Honolulu, HI 8. Department of Neurology, University of Washington, Seattle, WA 9. Department of Neurology, University of Kansas Medical Center, Kansas City 10. Department of Neurosciences, Overlook Medical Center, Summit, NJ 11. Western University Health Sciences College of Podiatric Medicine, Pomona, CA 1 Draft for Public Comment 12. Neuropathy Action Foundation, Santa Ana, CA 13. New West Physicians, Golden, CO 14. Leadership Sinai Centre for Diabetes, Mount Sinai Hospital, Toronto, ON 15. Department of Medicine, The University of Texas at Austin 16. Department of Neurology, University of Pennsylvania, Philadelphia 17.
    [Show full text]
  • Voltage-Gated Sodium Channels and Blockers: an Overview and Where Will They Go?*
    Current Medical Science 39(6):863-873,2019 DOICurrent https://doi.org/10.1007/s11596-019-2117-0 Medical Science 39(6):2019 863 Voltage-gated Sodium Channels and Blockers: An Overview and Where Will They Go?* Zhi-mei LI1, Li-xia CHEN2#, Hua LI1# 1Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China 2Wuya College of Innovation, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China Huazhong University of Science and Technology 2019 Summary: Voltage-gated sodium (Nav) channels are critical players in the generation and propagation of action potentials by triggering membrane depolarization. Mutations in Nav channels are associated with a variety of channelopathies, which makes them relevant targets for pharmaceutical intervention. So far, the cryoelectron microscopic structure of the human Nav1.2, Nav1.4, and Nav1.7 has been reported, which sheds light on the molecular basis of functional mechanism of Nav channels and provides a path toward structure-based drug discovery. In this review, we focus on the recent advances in the structure, molecular mechanism and modulation of Nav channels, and state updated sodium channel blockers for the treatment of pathophysiology disorders and briefly discuss where the blockers may be developed in the future. Key words: voltage-gated sodium channels; blockers; Nav channel structures; channelopathies Life did not come into existence until living In this review, we focus on voltage-gated organisms were enclosed by one or more membranes sodium (Nav) channels, which selectively conduct which cut them off from the chaotic world at a sodium ions movement in response to variations of molecular level.
    [Show full text]
  • Prescription Medications, Drugs, Herbs & Chemicals Associated With
    Prescription Medications, Drugs, Herbs & Chemicals Associated with Tinnitus American Tinnitus Association Prescription Medications, Drugs, Herbs & Chemicals Associated with Tinnitus All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form, or by any means, without the prior written permission of the American Tinnitus Association. ©2013 American Tinnitus Association Prescription Medications, Drugs, Herbs & Chemicals Associated with Tinnitus American Tinnitus Association This document is to be utilized as a conversation tool with your health care provider and is by no means a “complete” listing. Anyone reading this list of ototoxic drugs is strongly advised NOT to discontinue taking any prescribed medication without first contacting the prescribing physician. Just because a drug is listed does not mean that you will automatically get tinnitus, or exacerbate exisiting tinnitus, if you take it. A few will, but many will not. Whether or not you eperience tinnitus after taking one of the listed drugs or herbals, or after being exposed to one of the listed chemicals, depends on many factors ‐ such as your own body chemistry, your sensitivity to drugs, the dose you take, or the length of time you take the drug. It is important to note that there may be drugs NOT listed here that could still cause tinnitus. Although this list is one of the most complete listings of drugs associated with tinnitus, no list of this kind can ever be totally complete – therefore use it as a guide and resource, but do not take it as the final word. The drug brand name is italicized and is followed by the generic drug name in bold.
    [Show full text]
  • Drugs That Affect the Cardiovascular System
    PharmacologyPharmacologyPharmacology DrugsDrugs thatthat AffectAffect thethe CardiovascularCardiovascular SystemSystem TopicsTopicsTopics •• Electrophysiology Electrophysiology •• Vaughn-Williams Vaughn-Williams classificationclassification •• Antihypertensives Antihypertensives •• Hemostatic Hemostatic agentsagents CardiacCardiacCardiac FunctionFunctionFunction •• Dependent Dependent uponupon –– Adequate Adequate amountsamounts ofof ATPATP –– Adequate Adequate amountsamounts ofof CaCa++++ –– Coordinated Coordinated electricalelectrical stimulusstimulus AdequateAdequateAdequate AmountsAmountsAmounts ofofof ATPATPATP •• Needed Needed to:to: –– Maintain Maintain electrochemicalelectrochemical gradientsgradients –– Propagate Propagate actionaction potentialspotentials –– Power Power musclemuscle contractioncontraction AdequateAdequateAdequate AmountsAmountsAmounts ofofof CalciumCalciumCalcium •• Calcium Calcium isis ‘glue’‘glue’ that that linkslinks electricalelectrical andand mechanicalmechanical events.events. CoordinatedCoordinatedCoordinated ElectricalElectricalElectrical StimulationStimulationStimulation •• Heart Heart capablecapable ofof automaticityautomaticity •• Two Two typestypes ofof myocardialmyocardial tissuetissue –– Contractile Contractile –– Conductive Conductive •• Impulses Impulses traveltravel throughthrough ‘action‘action potentialpotential superhighway’.superhighway’. A.P.A.P.A.P. SuperHighwaySuperHighwaySuperHighway •• Sinoatrial Sinoatrial node node •• Atrioventricular Atrioventricular nodenode •• Bundle Bundle ofof
    [Show full text]
  • Dysarthria and Visual Hallucinations Due to Flecainide Toxicity
    Postgraduate Medical Journal (1986) 62, 61-62 Postgrad Med J: first published as 10.1136/pgmj.62.723.61 on 1 January 1986. Downloaded from Dysarthria and visual hallucinations due to flecainide toxicity Essam Ramhamadany, Simon Mackenzie and David R. Ramsdale Regional Cardiothoracic Unit, Broadgreen Hospital, Thomas Drive, Liverpool, L14 3LB, UK. Summary: A 65 year old man with recurrent ventricular tachyarrhythmias post myocardial infarction developed dysarthria and visual hallucinations due to flecaimnde toxicity. A readily available assay is required for estimating serum flecainide levels in patients with diminished renal or hepatic function or failed arrhythmia suppression. Introduction Flecainide acetate is a new Class IC antiarrhythmic within 8 hours the patient developed dysarthria and agent which stabilizes and slows conduction in atrial visual hallucinations. The latter involved visions of and ventricular myocardium, in conduction tissue and family members and imagined objects held in his in accessory pathways. It has been shown to be grasp. Persistence of these side effects and further effective against atrial, junctional and ventricular episodes of ventricular tachycardia during intraven- arrhythmias by increasing the QT interval and prolon- ous flecainide therapy necessitated its replacement by ging QRS duration. Serious central nervous system intravenous and oral disopyramide with satisfactory side effects are thought to be infrequent. We describe a results. Serum flecainide was found to be 2500 lg/l case of failed arrhythmia suppression associated with (therapeutic range 400-1000 #ig/l). Within 10 hours of by copyright. dysarthria and visual hallucinations due to flecainide withdrawing flecainide the dysarthria and the psy- toxicity. chological disturbance subsided. Blood urea was 7.6 mmol/l on day 14 but at the time of toxicity was 19.2 mmol/l.
    [Show full text]
  • Ibm Micromedex® Carenotes Titles by Category
    IBM MICROMEDEX® CARENOTES TITLES BY CATEGORY DECEMBER 2019 © Copyright IBM Corporation 2019 All company and product names mentioned are used for identification purposes only and may be trademarks of their respective owners. Table of Contents IBM Micromedex® CareNotes Titles by Category Allergy and Immunology ..................................................................................................................2 Ambulatory.......................................................................................................................................3 Bioterrorism ...................................................................................................................................18 Cardiology......................................................................................................................................18 Critical Care ...................................................................................................................................20 Dental Health .................................................................................................................................22 Dermatology ..................................................................................................................................23 Dietetics .........................................................................................................................................24 Endocrinology & Metabolic Disease ..............................................................................................26
    [Show full text]
  • Combined Anti-Arrhythmic Therapywith Class 1 and Class 3 Drugs
    Postgrad Med J: first published as 10.1136/pgmj.65.766.519 on 1 August 1989. Downloaded from Postgraduate Medical Journal (1989) 65, 519 - 524 Combined anti-arrhythmic therapy with class 1 and class 3 drugs M.A. James,* P. Papouchado and J.V. Jones Department ofCardiology, Bristol Royal Infirmary, Bristol BS2 8HW, UK. Summary: This study was designed to investigate the differences in efficacy between 3 different combinations ofamiodarone and a class 1 anti-arrhythmic drug (one from each class). The purpose was to determine whether the known differing electrophysiological properties of class 1 drugs result in any particular one making a superior combination with the class 3 drug amiodarone. Eight patients were studied in a randomized single blind cross-over trial. Amiodarone and flecainide proved to be the superior combination producing a signiflcantiy greater reduction in mean ectopic counts/24 hours than the amiodarone/mexilitene combination (1,286 vs 3,243; P <0.05) or the amiodarone/disopyramide combination (3,795; P < 0.05). All 3 combinations reduced mean ectopic counts from the baseline value (8,729), but this was only significant for amiodarone/flecainide (P <0.01) and amiodarone/ mexilitene (P<0.05). In addition the amiodarone/flecainide combination produced a significant reduction in complex forms of arrhythmia with ventricular tachycardia abolished in all cases, which was not achieved by any other combination. Introduction the QT interval but without altering the JT interval and class lb drugs shorten both. Since both class la copyright. It is probable that combinations of anti-arrhythmic and class 3 drugs prolong repolarization, and hence drug therapy will be tried for patients with refractory, the QT interval, it has been suggested that their life threatening ventricular arrhythmias.
    [Show full text]
  • 2021 Equine Prohibited Substances List
    2021 Equine Prohibited Substances List . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s). Prohibited Substances that are identified as Specified Substances in the List below should not in any way be considered less important or less dangerous than other Prohibited Substances. Rather, they are simply substances which are more likely to have been ingested by Horses for a purpose other than the enhancement of sport performance, for example, through a contaminated food substance. LISTED AS SUBSTANCE ACTIVITY BANNED 1-androsterone Anabolic BANNED 3β-Hydroxy-5α-androstan-17-one Anabolic BANNED 4-chlorometatandienone Anabolic BANNED 5α-Androst-2-ene-17one Anabolic BANNED 5α-Androstane-3α, 17α-diol Anabolic BANNED 5α-Androstane-3α, 17β-diol Anabolic BANNED 5α-Androstane-3β, 17α-diol Anabolic BANNED 5α-Androstane-3β, 17β-diol Anabolic BANNED 5β-Androstane-3α, 17β-diol Anabolic BANNED 7α-Hydroxy-DHEA Anabolic BANNED 7β-Hydroxy-DHEA Anabolic BANNED 7-Keto-DHEA Anabolic CONTROLLED 17-Alpha-Hydroxy Progesterone Hormone FEMALES BANNED 17-Alpha-Hydroxy Progesterone Anabolic MALES BANNED 19-Norandrosterone Anabolic BANNED 19-Noretiocholanolone Anabolic BANNED 20-Hydroxyecdysone Anabolic BANNED Δ1-Testosterone Anabolic BANNED Acebutolol Beta blocker BANNED Acefylline Bronchodilator BANNED Acemetacin Non-steroidal anti-inflammatory drug BANNED Acenocoumarol Anticoagulant CONTROLLED Acepromazine Sedative BANNED Acetanilid Analgesic/antipyretic CONTROLLED Acetazolamide Carbonic Anhydrase Inhibitor BANNED Acetohexamide Pancreatic stimulant CONTROLLED Acetominophen (Paracetamol) Analgesic BANNED Acetophenazine Antipsychotic BANNED Acetophenetidin (Phenacetin) Analgesic BANNED Acetylmorphine Narcotic BANNED Adinazolam Anxiolytic BANNED Adiphenine Antispasmodic BANNED Adrafinil Stimulant 1 December 2020, Lausanne, Switzerland 2021 Equine Prohibited Substances List . Prohibited Substances include any other substance with a similar chemical structure or similar biological effect(s).
    [Show full text]
  • Neuropathic Pain Therapeutic Class Review
    Neuropathic Pain Therapeutic Class Review (TCR) November 12, 2019 No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, digital scanning, or via any information storage or retrieval system without the express written consent of Magellan Rx Management. All requests for permission should be mailed to: Magellan Rx Management Attention: Legal Department 6950 Columbia Gateway Drive Columbia, Maryland 21046 The materials contained herein represent the opinions of the collective authors and editors and should not be construed to be the official representation of any professional organization or group, any state Pharmacy and Therapeutics committee, any state Medicaid Agency, or any other clinical committee. This material is not intended to be relied upon as medical advice for specific medical cases and nothing contained herein should be relied upon by any patient, medical professional or layperson seeking information about a specific course of treatment for a specific medical condition. All readers of this material are responsible for independently obtaining medical advice and guidance from their own physician and/or other medical professional in regard to the best course of treatment for their specific medical condition. This publication, inclusive of all forms contained herein, is intended to be educational in nature and is intended to be used for informational purposes only. Send comments and suggestions to [email protected]. November
    [Show full text]