Authors: Pallavi Subhraveti Peter D Karp Ingrid Keseler An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Anamika Kothari Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_000308495Cyc: Nocardia brevicatena NBRC 12119 Cellular Overview Connections between pathways are omitted for legibility. Ron Caspi

Cofactor, Carrier, and Vitamin Biosynthesis Nucleoside and Nucleotide Degradation Chlorinated Compound Degradation 6 37 a nascent β-D-fructofuranose D-sedoheptulose a sulfurated N -dimethylallyladenosine a holo-[DhbB aryl- + (S)-4-hydroxy- a ribonucleoside an L-glutamyl- mycofactocin biosynthesis superpathway of pyrimidine adenosylcobinamide a purine 2,3- menadione NADH H a [glutamine- met F0F1 ATP Fermentation mixed acid fermentation in tRNA peptidoglycan 1-phosphate 2-oxopentanoate Gln 1,7-bisphosphate + + cob(II)yrinate a,c- [2Fe-2S] iron-sulfur cob(II)yrinate a,c-diamide flavin biosynthesis I (bacteria and plants) superpathway of coenzyme A biosynthesis I (bacteria) superpathway of tetrahydrofolate biosynthesis superpathway of thiamine diphosphate biosynthesis II 2-methyladeninyl Tetrapyrrole Biosynthesis 1,2-dichloroethane [sulfur carrier] carrier protein] ATP diphosphate [tRNA ] ATP dGDP H H mycothiol biosynthesis deoxyribonucleosides degradation ribonucleoside dihydroxybenzoate (meso-DAP synthetase]- biotin synthase diamide biosynthesis I cluster biosynthesis biosynthesis II (late degradation class 1b Asp-tRNA(Asn) bifunctional a C-terminal adenosylcobamide biosynthesis inosine 5'- 5'-triphosphate containing) L-tyrosine class 1b (early cobalt insertion) 3-methyl-2- a 5,10- D-glucopyranose phosphoenolpyruvate 2'-deoxycytidine superpathway of purine deoxyribonucleosides degradation ribonucleoside- /Glu-tRNA(Gln) glutamate N- [mycofactocin cobalt incorporation) from adenosylcobinamide-GDP tetrapyrrole biosynthesis siroheme biosynthesis phosphate NADH-quinone fructose- 4-hydroxy-2- fructose- ribonucleoside- GTP oxobutanoate methylenetetrahydrofolate GTP cys 6-phosphate I (from glutamate) 1,2-dichloroethane succinate 2,3- diphosphate amidotransferase acetyltransferase/ a reduced precursor uroporphyrinogen-III L-cysteine desulfurase uroporphyrinogen-III 2-methyladenine degradation bifunctional oxidoreductase: bisphosphate oxovalerate bisphosphate biotin--[acetyl- diphosphate nucleoside haloalkane dehydrogenase dihydroxybenzoate- endolytic adenylyltransferase/ reductase subunit GatB: amino-acid H O c-type peptide]-glycyl-L-[mycofactocin uroporphyrin-III adenosylcobinamide ON20_RS12320 aldolase: aldolase: dmpG aldolase: reductase 2 uroporphyrin-III cysteine inositol-3- nicotinate-nucleotide-- pyruvate kinase: pyk phosphoenolpyruvate 2'-deoxyguanosine sulfurtransferase CoA-carboxylase] cytochrome valyl-L-tyrosine cysteine GTP 3-methyl-2-oxobutanoate a ThiS sulfur- uroporphyrinogen-III deaminase: dehalogenase: hydrophobic AMP ligase: entE transglycosylase subunit ON20_RS17705 ON20_RS24140 acetyltransferase cytochrome precursor methyltransferase: methyltransferase: GTP phosphate dimethylbenzimidazole glu carboxylase: IMP kinase/ ON20_RS12325 MoeZ: ON20_RS24140 4-hydroxy-2- ligase: subunit c oxidase an oxidized desulfurase: cyclohydrolase II: hydroxymethyltransferase: carrier protein desulfurase: uroporphyrin-III ON20_RS27995 thymidine ON20_RS26340 membrane 2,3- MltG: beta: nrdF ArgJ: peptide]-tyrosine ON20_RS23165 ON20_RS23165 cyclohydrolase synthase: phosphoribosyltransferase: glutamate-- ON20_RS09620 2'-deoxyadenosine IMP adenosylcobinamide- ON20_RS12335 ON20_RS19505 class II fructose- oxovalerate Asp-tRNA(Asn) class II fructose- ON20_RS05090 beta: nrdF O c-type panB ON20_RS15480 methyltransferase: 2-chloroethanol anchor subunit: dihydroxybenzoate- ON20_RS15875 ON20_RS09685 2 a C-terminaldecarboxylase: uroporphyrinogen-III ON20_RS15480 ON20_RS13090 I FolE: folE ON20_RS24905 tRNA ligase: pyruvate [+ 3 isozymes] dehydrogenase: phosphate ON20_RS12340 bisphosphate aldolase: dmpG class 1b /Glu-tRNA(Gln) bisphosphate a cytochromereduced uroporphyrinogen-III cobT ON20_RS23165 thymidine ON20_RS04840 class 1b [mycofactocinON20_RS22585 cysteine asp 7,8- cysteine ON20_RS17620 purine-nucleoside ON20_RS21125 guanylyltransferase: AMP ligase: entE [+ 3 isozymes] ON20_RS12345 bifunctional [glutamine ribonucleoside- amidotransferase: amino-acid N- H O c-type C-methyltransferase: C-methyltransferase: bifunctional an L-glutamyl- phosphorylase: aldolase: aldolase: 2 dihydroneopterin desulfurase: UDP-N-acetyl- 2-methyladenine uroporphyrinogen-III oxaloacetate 2'-deoxyuridine synthetase] acetyltransferase: biotinyl-5'- ribonucleoside- precursor peptide]- desulfurase: 3,4-dihydroxy- 2-dehydropantoate Ins(3)P Glu phosphorylase: XMP tRNA (N6-isopentenyl ON20_RS08485 ON20_RS12350 ON20_RS24125 diphosphate ON20_RS17780 ON20_RS24125 RS17990 cytochrome cobA cobA aspartate 1- a carboxy- ribotide phosphate [tRNA ] ON20_RS04855 adenosine diphosphate an oxidized glycyl-L-valyl- ON20_RS17820 3'-triphosphate ON20_RS17820 α-D-glucosamine C-methyltransferase: ON20_RS04900 adenosine(37)-C2)- a 2,3- a mature a nascent ON20_RS12355 adenylyltransferase/ acetaldehyde pyruvate reductase ON20_RS17785 ON20_RS16725 adenylate precorrin-1 precorrin-1 2-butanone- adenylated- an [L-cysteine deaminase: adenosyl- reductase O c-type decarboxylase: cobA purine-nucleoside [glutamine synthetase]- an L-glutaminyl- N-acetyl-L- 2 decarboxylated 4-phosphate glutamyl-tRNA thymine ON20_RS04860 chloroacetaldehyde methylthiotransferase cobinamide dihydroxybenzoyl- peptidoglycan peptidoglycan ON20_RS12360 subunit alpha: thr thr an S-sulfanyl-[L- ON20_RS01535 [ThiS sulfur- desulfurase]-S- D-inositol-3-phosphate adenosylcobinamide- precorrin-1 phosphorylase: adenylyl-L-tyrosine [tRNA Gln ] D-erythrose methionine subunit alpha: RS11385 cytochrome L-tyrosine3-amino-5-[(4- uroporphyrin-III uroporphyrin-III synthase/GTP reductase: (R)-lactate uracil MiaB: ON20_RS16630 phosphate a purine [DhbB aryl- with (L-alanyl- (meso-DAP ON20_RS12365 DHAP D-glyceraldehyde a 2'- ON20_RS18170 DHAP serine serine cysteine desulfurase] carrier protein] sulfanyl-L-cysteine glycosyltransferase: GDP formate acetyl-CoA purine-nucleoside ON20_RS04900 phosphorylase: 4-phosphate ON20_RS18170 hydroxyphenyl) methyltransferase: methyltransferase: cyclohydrolase II: 7,8- ON20_RS23175 phosphorylase: aldehyde ribonucleoside carrier protein] γ-D-glutamyl- containing) with ON20_RS12370 deoxyribonucleoside β-alanine mshA ribazoletransferase: uroporphyrin-III (S)-malate ON20_RS23165 scaffold protein ON20_RS23165 (R)-pantoate phosphorylase: 6 5'-diphosphate GlcNAc terminus ON20_RS08365 GDP methyl]-4,4- ON20_RS15660 dihydroneopterin cysteine D-glyceraldehyde ON20_RS08470 (S)-4-amino-5- methyltransferase: ON20_RS04855 2'-deoxyinosine dehydrogenase 2-methylsulfanyl-N - meso-2,6- ON20_RS12380 5'-diphosphate uroporphyrinogen-III for iron-sulfur 2,5-diamino-6- Coα-[α-(2- oxopentanoate ON20_RS04900 xanthosine (NADP(+)): 5'-deoxyadenosine 37 an unsulfurated diaminopimeloyl- a metal a metal dimethylpyrrolidin- uroporphyrinogen-III 3'-phosphate chorismate desulfurase: 3-phosphate 1-O-(2-acetamido- ON20_RS23165 phosphate acetaldehyde citrate synthase fumarate hydratase: dimethylallyladenosine met RS03005 cluster assembly: (5-phospho-D- methyladenin-9-yl)]-Co [sulfur carrier] D-alanine) cation cation 2-one synthase: C-methyltransferase: C-methyltransferase: pantoate--beta- ON20_RS15480 1-deoxy-D- 2-deoxy-α-D- glutamate-1- acetyltransferase: dehydrogenase 2: ON20_RS02880 ON20_RS13940 ON20_RS31920 in tRNA a [glutamine ON20_RS15475 β uroporphyrinogen-III 2-deoxy-α-D-ribose 1-phosphate ON20_RS22585 cobA cobA ribosylamino) aminodeoxychorismate/ gly -adenosylcobamide class II fumarate tetrapeptide + synthetase]-O a C-terminal an S-sulfanyl-[cysteine D-ribulose alanine ligase: cysteine xylulose-5- glucopyranosyl)-1D-myo semialdehyde C-methyltransferase: ON20_RS23970 (acetylating): [+ 2 isozymes] uracil 2-deoxy-α-D- purine-nucleoside aldehyde NAD menadiol pyrimidin- ON20_RS01530 anthranilate synthase 5'-phosphate CO H hydratase: aspA 4 -(5'-adenylyl) [mycofactocin desulfurase]-[disordered- 5-phosphate desulfurase: phosphate -inositol 3-phosphate menaquinol-7 biosynthesis 2,1-aminomutase: cobA 2 2 ON20_RS01845 ribose 1-phosphate phosphorylase: dehydrogenase precorrin-2 precorrin-2 4(3H)-one D-erythro-7,8- component II: glycine -L-tyrosine a metal a metal precursor peptide]- form scaffold ON20_RS17820 synthase: ON20_RS09410 [+ 2 isozymes] ON20_RS04900 (NADP(+)): RS19875 3,4-dihydroxy- dihydroneopterin ON20_RS00035 oxidase acetyl phosphate citrate fumarate cation cation glycyl-3-amino-5- precorrin-2 precorrin-2 C(20)- dxs all-trans- glutamate-1- precorrin-2 ON20_RS07855 protein] complex 2-butanone- (R)-pantothenate ThiO: thiO α α xanthine [(4-hydroxyphenyl) dehydrogenase: [cysteine desulfurase]-S- methyltransferase: dihydroneopterin aminodeoxychorismate 1-deoxy-D- Co -[ -(2- heptaprenyl 1,4-dihydroxy- semialdehyde- 2-deoxy-D-ribose 5-phosphate a peptidoglycan a nascent peptidoglycan a [2-oxoglutarate dehydrogenase E2 a DNA containing molybdopterin a [glutamine a 6-(N-acetyl-α- D-sedoheptulose 4-phosphate a thiocarboxy- 1-(2-acetamido- precorrin-2 acetate kinase: acetaldehyde aconitate fumarate reductase/ 2-chloroacetate a holo-[EntB aryl- an N-modified a nucleoside an L-asparaginyl- an L-cysteinyl- NADH methyl]-4,4- cobA sulfanylcysteine:[acceptor 5-amino-6-(5- aldolase: folB synthase xylulose 5- methyladenin-7-yl)]-Co diphosphate 2-naphthoate 2-deoxy-D-ribose γ γ 6 2,3- an apurinic/ tungstate adenine synthetase]-O D-glucosaminyl)- ON20_RS13670 type III 2-iminoacetate 2-deoxy-α-D- 2,1- hydratase: acnA succinate with (L-alanyl- -D- with (L-alanyl- -D- protein] N -dihydrolipoyl-L-lysine triphosphate RNA Asn 1-phosphate Cys dADP synthase: SAM [ThiS-Protein] β-adenosylcobamide dehydrogenase: ON20_RS23965 5-phosphate carrier protein] 4 aminoacyl-[tRNA] [tRNA ] [tRNA ] a metal a metal dimethylpyrrolidin- protein]-cysteine phospho-D- pantothenate 6-(hydroxymethyl) component I: pabB AIR phosphate aminomutase: glutamyl-meso-2,6- glutamyl-meso-2,6- 2-oxoglutarate dihydroxybenzoate apyrimidinic site dinucleotide -(5'-adenylyl) 1-phosphatidyl- RS10750 sirohydrochlorin ON20_RS30140 glucopyranosyl)- cobA bifunctional dehydrogenase deoxyribose- cation cation 2-one sulfurtransferase: precorrin-3A ribosylamino)uracil -7,8-dihydropterin 1,4-dihydroxy- heme a biosynthesis cis-aconitate diaminopimeloyl-D- diaminopimeloyl-D- dehydrogenase, -L-tyrosine 1D-myo-inositol class 1b kinase: 4-amino-4- 1D-myo-inositol hemL acetate acetaldehyde- flavoprotein subunit: phosphate aldolase: NAD(+) ON20_RS17820 bifunctional thiazole 2-naphthoate deoxyribose- E2 component, molybdopterin fructose- ribonucleoside- ON20_RS01540 2-amino-4-hydroxy-6- deoxychorismate phosphomethylpyrimidine sirohydrochlorin CoA/alcohol ON20_RS11800 urate alanine) tetrapeptide alanine) tetrapeptide 2,3- endonuclease peptidyl-tRNA DNA-directed peptidyl-tRNA peptidyl-tRNA a [cysteine desulfurase]- precorrin- synthase: N-acetyl-1-D-myo- polyprenyltransferase: phosphate ON20_RS23335 molybdotransferase bisphosphate diphosphatase: diphosphate 3,4-dihydroxy- hydroxymethyldihydropteridine 5-aminolevulinate protoheme aconitate glycolate dihydrolipoamide dihydroxybenzoate- III: nth bifunctional [glutamine hydrolase: RNA polymerase: GlcNAc-PI de- hydrolase: S-sulfanyl-[disordered- 3B type I aminodeoxychorismate synthase ThiC: inositol-2-amino- ON20_RS23000 dehydrogenase: fumarate reductase/ aldolase: hydrolase: ON20_RS19420 a metal a metal 5-amino-6-(5- 2-butanone- diphosphokinase: folK thiG sirohydrochlorin protoheme IX hydratase: acnA aldolase: succinyltransferase: sucB MoeA: rpoC reductase RS11050 3-amino-5-[(4- form scaffold synthase: pantothenate lyase: ON20_RS02540 ON20_RS23755 2-deoxy-alpha- D- porphobilinogen ON20_RS09525 L,D- AMP ligase: entE bifunctional DNA- synthetase] ON20_RS17980 N-acetylase: ON20_RS17980 ON20_RS17980 cation cation cobalt- 4-phosphate (7,8-dihydropterin- adenosylcobalamin chelatase: farnesyltransferase: succinate ON20_RS23335 acetaldehyde D-glyceraldehyde 3-phosphate ON20_RS18210 ON20_RS22775 ON20_RS24140 subunit hydroxyphenyl) protein] complex cobG phospho-D- kinase: glucopyranoside transpeptidase: multifunctional oxoglutarate 2,3- formamidopyrimidine adenylyltransferase/ aminoacyl-tRNA ON20_RS16690 aminoacyl-tRNA aminoacyl-tRNA reduced β- sirohydrochlorin synthase/GTP 2-[(2R,5Z)- salvage from cobalamin synthase: ON20_RS19470 ON20_RS15540 ethanol D-threo-isocitrate dehydrogenase class II fructose- beta: nrdF methyl]-4,4- cysteine ribitylamino)uracil ON20_RS20960 6-yl)methyl 4-aminobenzoate deacetylase: mshB demethylmenaquinol-7 ON20_RS28980 decarboxylase/oxoglutarate dihydroxybenzoate- glycosylase/ molybdopterin [glutamine synthetase]- hydrolase: [+ 2 isozymes] GlcNAc-PI de- hydrolase: hydrolase: cyclohydrolase II: HMP-P 2-carboxy-4- ON20_RS23160 ferroheme o flavoprotein: D-glyceraldehyde acetaldehyde bisphosphate nicotinamide D- dimethyl-2- desulfurase: precorrin-3B diphosphate sirohydrochlorin acetaldehyde [+ 2 isozymes] dehydrogenase thiamine AMP ligase: entE DNA-(apurinic or molybdotransferase adenylyl-L-tyrosine ON20_RS21425 N-acetylase: ON20_RS21425 ON20_RS21425 AMP class 1b a metal a metal ON20_RS15660 (R)-4'- methylthiazol-5(2H cob(I)alamin demethylmenaquinone porphobilinogen NADP-dependent ON20_RS25180 3-phosphate dehydrogenase aldolase: ribonucleotide RS23645 pyrrolidinone ON20_RS15480 GlcN-Ins chelatase: pyrophosphate-binding MoeA: phosphorylase: ribonucleoside- cation cation precorrin-3B (C 17 )- phosphopantothenate bifunctional )-ylidene]ethyl synthase: isocitrate ON20_RS25185 (acetylating): apyrimidinic site) ON20_RS09345 1-deoxy-L- dihydropteroate methyltransferase: ON20_RS07455 heme A synthase: acetaldehyde ON20_RS21600 ON20_RS08365 RNA ON20_RS24125 diphosphate cysteine hydroxymethylpyrimidine phosphate dehydrogenase: thymine degradation a nascent peptidoglycan subunit/dihydrolipoyllysine- a 2,3- lyase: ON20_RS17465 cobalt-factor III methyltransferase: glycero-tetrulose bifunctional synthase: folP cysteine--1-D-myo- ON20_RS22905 ON20_RS28060 ON20_RS15520 dehydrogenase ON20_RS01845 an uncharged desulfurase: ARP succinate residue succinyltransferase an N-modified Asn Cys reductase ON20_RS13670 phosphopantothenoylcysteine kinase/ cob(II)alamin inosityl 2-amino- siroheme Macromolecule Modification ON20_RS04700 [+ 2 isozymes] with L,D cross links D-ala dihydroxybenzoyl- 6-(α-D- asn tRNA cys a tRNA 4-phosphate dihydropteroate (acetylating): subunit: ON20_RS20170 WO - amino acid tRNA subunit alpha: a metal a metal 5-[(4-hydroxyphenyl) ON20_RS17820 decarboxylase/ phosphomethylpyrimidine menaquinol-7 porphobilinogen ferroheme i thymine (meso-diaminopimelate [EntB aryl- 2 a [glutamine- acetate glucosaminyl)- DHAP D-erythrose RS23650 an S-sulfanyl-[cysteine synthase: folP 2-carboxy-1,4- 2-deoxy-alpha-D- 2-oxoglutarate ON20_RS01845 purine ribonucleosides degradation a [2-oxoglutarate dehydrogenase E2 a 3'-terminal a 5'-phospho- molybdopterin ON20_RS18170 cation cation methyl]-3-imino-4,4- precorrin-4 phosphopantothenate--cysteine kinase: thiD cob(I)yrinic acid acetyl-CoA containing) carrier protein] AMP synthetase]- 1-phosphatidyl- desulfurase]-S- 6,7-dimethyl-8- naphthoquinol biosynthesis 2-(2-carboxy-4- glucopyranoside hydroxymethylbilane tRNA processing [+ 2 isozymes] protein] N 6 -S-succinyldihydrolipoyl-L-lysine unsaturated sugar [DNA] cofactor ADP a,c-diamide heme A synthase: L-tyrosine 1D-myo-inositol ADP dimethylpyrrolidin- sulfanyl-[disordered- precorrin-4 C(11)- ribityllumazine ligase CoaBC: ON20_RS15740 7,8- methylthiazol-5- ligase: mshC synthase: hemC HMP-PP adenosyltransferase: ON20_RS15520 5,6-dihydrothymine 2-one cobalt-precorrin-3 form scaffold methyltransferase: synthase: (R)-4'- dihydropteroate chorismate yl)ethyl phosphate a polycistronic acetyl-CoA adenosine ON20_RS05445 deacetylmycothiol hydroxymethylbilane potassium- protein] complex cobM ON20_RS15655 phosphopantothenoyl- isochorismate tRNA precursor hydantoinase/ cobalt-precorrin 3 [cysteine desulfurase]-S- bifunctional synthase: hydroxyferroheme i K + transporting K + L-cysteine synthase: thiamine cob(I)yrinic acid adenosine oxoprolinase di-trans,octa-cis an O 6 - a 2'- 3-oxo-23,24- an N-terminal- methyltransferase: sulfanylcysteine:[acceptor folylpolyglutamate mycothiol ON20_RS23170 UDP-N-acetyl- a [protein]- a [protein]- a DNA methyl a carboxy- UDP-N-acetyl- queuosine at ATPase precorrin-5 6,7-dimethyl-8-(1- bifunctional a,c-diamide family protein: an L-aspartyl- sec carbonic acid synthase/ ON20_RS24485 phosphate synthase: deaminase: -undecaprenyl α-D-muramoyl- methylguanine adenylated- cys deoxyribonucleoside α-D-muramoyl- D-glt bisnorchol-1,4- L-methionyl-L- glu position 34 ser a tRNA ON20_RS23165 protein]-cysteine dGTP L-cysteine L-cysteine phosphotriester [DNA] [tRNA Asn ] ATP roseoflavin PMFT D-ribityl)lumazine phosphopantothenoylcysteine isochorismate synthase: adenosyltransferase: preuroporphyrinogen ON20_RS04860 ON20_RS10235 phosphate γ in DNA 5'-triphosphate dien-22-yl-CoA alanyl-[protein] Asp sulfurtransferase: precorrin- dihydrofolate adenosylcobinamide-GDP mshD phospho-N- L-alanyl- -D- [ThiS sulfur- L-alanine 3-ketosteroid-9- Asp-tRNA(Asn) of a tRNA 5'-phosphate cobO + + cobalt-precorrin-4 riboflavin decarboxylase/ synthase: ON20_RS23915 [+ 4 isozymes] glutamyl-meso-2,6- carrier protein] K RS00065 K mycofactocin system ON20_RS17820 6A synthase 2-succinyl-5- salvage from cobinamide I uroporphyrinogen- a tRNA precursor a tRNA precursor with acetylmuramoyl- alpha-hydroxylase /Glu-tRNA(Gln) carbonic a [cysteine synthase: phosphopantothenate--cysteine ON20_RS06925 cob(II)alamin- mycothiol ferroheme a xanthosine adenosine inosine guanosine diaminopimeloyl- methylated-DNA-- methylated-DNA-- glycosyltransferase: (deacetylating): enolpyruvyl- III synthase: with a 5' extension a 5' extension and 3-(carbamoylamino)- pentapeptide- group II UDP-N- subunit A: amidotransferase type I methionyl tRNA glutamyl- serine-- anhydrase: cobalt precorrin- desulfurase]-(S- ON20_RS15665 ligase CoaBC: ON20_RS15740 thiamine [corrinoid D-alanyl-D-alanine deoxyguanosinetriphosphate [protein]-cysteine S- [protein]-cysteine S- bifunctional mftF 11 ON20_RS21845 7,8-dihydrofolate cob(II)inamide and a long 3' trailer a short 3' extension 2-methylpropanoate transferase: cysteine intron reverse acetylmuramoyl- ON20_RS14500 subunit GatB: aminopeptidase: Q(34) synthetase tRNA ligase: 4 (C )- sulfanyl) -[disordered- 6-hydroxy-3- phosphate adenosyltranferase] ON20_RS19475 methyltransferase: methyltransferase: ON20_RS16200 2 cob(I)yrinic acid ribonuclease ON20_RS08745 triphosphohydrolase: desulfurase: transcriptase/ L-alanine--D- map GluQRS: ON20_RS00340 riboflavin methyltransferase: form scaffold riboflavin 4'-phosphopantetheine monoglutamate cyclohexene- molybdenum cofactor biosynthesis Polyprenyl Biosynthesis ribonuclease D: ON20_RS20830 3-ketosteroid-9- ON20_RS17705 [+ 2 isozymes] nitrate RS19490 nitrate MFT-1 precorrin-6A thiamine- a,c-diamide uroporphyrinogen-III ribonuclease PH: P protein purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside ON20_RS27730 ON20_RS20830 ON20_RS17820 maturase: ltrA glutamate ligase: ON20_RS00965 kinase/FAD cobA protein] complex 1-carboxylic- ON20_RS16300 alpha-hydroxylase Asp-tRNA(Asn) [+ 2 isozymes] serine-- bifunctional pantetheine- phosphate kinase: adenosyltransferase: ribonuclease D: ON20_RS05620 component: phosphorylase: phosphorylase: phosphorylase: phosphorylase: deoxyguanosinetriphosphate methylated-DNA-- methylated-DNA-- ON20_RS08750 synthetase: mycofactocin system acid synthase: trans, trans-farnesyl cysteine group II subunit A: /Glu-tRNA(Gln) tRNA ligase: cobalt- phosphate ON20_RS17545 cob(I)alamin- ON20_RS16300 rnpA NADH repair ON20_RS04900 ON20_RS04900 ON20_RS04900 ON20_RS04900 (R)-3-amino-2- [protein]-cysteine S- [protein]-cysteine S- ribF riboflavin ON20_RS20795 ON20_RS05445 cys geranyl diphosphate pyrimidine deoxyribonucleotides triphosphohydrolase: desulfurase: intron reverse α ON20_RS01930 glutamyl- ON20_RS27055 CO H O glycosyltransferase: menaquinol-11 biosynthesis diphosphate methyltransferase: 9 -hydroxy-3-oxo- amidotransferase: an N-terminal L- 2 2 precorrin-5A kinase/FAD adenylyltransferase: [corrinoid ATP biosynthesis methylpropanoate ON20_RS07690 methyltransferase: nitrate RS07865 nitrate mftF a 7,8-dihydrofolate thiamine cob(I)yrinic acid biosynthesis a tRNA precursor with dephosphorylation undecaprenyldiphospho- UMP ON20_RS15480 transcriptase/ UDP-N-acetyl- 23,24-bisnorchol- ON20_RS17780 met alanyl-[protein] queuosine at a [cysteine desulfurase]- synthetase: ON20_RS17490 2-succinyl-5- adenosyltranferase] cysteine α-D-ribose- ON20_RS24035 ON20_RS24035 roseoflavin all-trans- diphosphate a,c-diamide a short 3' extension NADH nucleoside triphosphate N-acetylmuramoyl-L- maturase: ltrA α-D-muramoyl-L- ON20_RS17785 position 34 precorrin-6B enolpyruvyl- cob(I)yrinic acid desulfurase: a tRNA precursor 1-phosphate 1,4-dien-22-yl-CoA an L-seryl- MFT-2 [scaffold protein- ribF undecaprenyl 1,4-dihydroxy- 3'-dephospho- dihydrofolate adenosyltransferase: GTP IPP IPP alanyl-γ-D-glutamyl-meso alanyl-D-glutamate an L-asparaginyl- of a tRNA Asp adenine 6-hydroxy-3- a,c-diamide pyrophosphohydrolase: sec (2Fe-2S)] complex 2-naphthoate CoA reductase: ON20_RS15480 isopentenyl- with a 5' extension α-D-ribose 1,5- triphosphate a [protein]-S- a [protein]-S- a thiocarboxy- [tRNA Asn ] [tRNA ] dinucleotide cobalt- diphosphate [corrinoid cobO prenyltransferase: ON20_RS28640 -2,6-diaminopimeloyl- 2'-deoxyguanosine ala nitrate RS11875 nitrate FMN cyclohexene- adenosyltransferase: diphosphate a guanine in DNA [DNA] AMP [ThiS-Protein] precorrin-5B dephospho- ON20_RS26480 adenosyltranferase]- cysteine GTP 3',8- ON20_RS13270 ribonuclease PH: ribonuclease D: phosphomutase: dCTP dCMP D-alanyl-D-alanine methyl-L-cysteine methyl-L-cysteine [DNA] 1-carboxylic- ON20_RS05445 a carboxy- Delta-isomerase: bifunctional 1,4-dihydroxy- CoA kinase: [+ 3 isozymes] cob(II)inamide desulfurase: cyclase MoaA: geranyl ribonuclease ON20_RS05620 ON20_RS16300 ON20_RS04895 2-naphthoate acid synthase: menaquinol-8 biosynthesis cob(I)yrinic acid adenylated ON20_RS17820 ON20_RS09760 a [co-chaperone]- precorrin-7 riboflavin ON20_RS09315 ON20_RS18205 diphosphate P protein (R)-NADHX D-ribose 5- Co 2+ Co 2+ MMFT-2 a tetrahydrofolate ON20_RS22985 [small subunit of an [L-cysteine dUTP diphosphatase: polyprenyltransferase: a,c-diamide (8S)-3',8-cyclo-7,8- DMAPP phosphate 4 2+ RS22090 2+ [scaffold protein- kinase/FAD component: ON20_RS16360 a ring-opened 7- an O - a [ThiI sulfur- an N-terminal- 3-oxo-4- an N-terminal- 6-O-trans- Mg Mg cobalt- ON20_RS23000 coenzyme A 2-succinyl-5- adenosyltransferase: molybdopterin desulfurase]-S- dihydroguanosine NAD(P)H-hydrate a [protein]- hydrogen mycofactocin system (2Fe-2S)] complex synthetase: demethylmenaquinol-8 rnpA methylguanine hydrogen selenide O-succinyl-L- methyl red a uracil in DNA Ala A(H2) a cytidine 34 enolpyruvoyl-6- [corrinoid synthase] sulfanyl-L-cysteine epimerase: nucleoside triphosphate O-acetyl-L-serine L-cysteine methylthymine carrier protein]- cys L-methionyl-L- pregnene-20- L-methionyl-L- a glycyl-[tRNA ] peroxide methoxy-mycolyl- lys precorrin-6A cobO 5'-triphosphate prenyltransferase: homoserine Ile2 glycosyltransferase: ribF demethylmenaquinone (S)-NADHX pyrophosphohydrolase: in DNA in DNA L-cysteine threonyl-[protein] carboxyl-CoA seryl-[protein] trehalose 6- in tRNA hydroxy-3-cyclohexene- adenosyltranferase]- adenosylcob(III) cyclic pyranopterin ON20_RS13270 ON20_RS23260 3-ketosteroid-9- mftF cobalt-precorrin- methyltransferase: 2+ 2+ DMKH2-11 pyridoxal 5'-phosphate biosynthesis I 1-carboxylate cob(I)inamide alamin-[corrinoid ON20_RS28640 phosphatetrehalose- Mg RS18165 Mg 6A reductase: precorrin-8x FAD ON20_RS22905 monophosphate NAD(P)H-hydrate FMN-dependent uracil-DNA alpha-hydroxylase catalase/ a [chaperone-ATP]- adenosyltranferase] geranyl Fatty Acid and dUTP dUMP bifunctional DNA- bifunctional o- methylated-DNA-- O-succinylhomoserine cysteine type I methionyl type I methionyl D-tyrosyl- phosphatase: tRNA MMFT-3 ON20_RS13680 demethylmenaquinone menaquinol-8 cob(I)yrinic acid synthase: dehydratase: NADH- glycosylase: subunit A: peroxidase [co-chaperone]- precorrin-8X D-erythrose diphosphate an uncharged tRNA Lipid Degradation formamidopyrimidine acetylhomoserine/ [protein]-cysteine S- sulfhydrylase: desulfurase: aminopeptidase: aminopeptidase: otsB lysidine(34) methyltransferase: a,c-diamide cob(I)yrinic acid a thiocarboxylated ON20_RS18215 ON20_RS21210 azoreductase: ON20_RS28840 ON20_RS14500 tRNA(Tyr) HPI: katG cobalt- [scaffold protein- methylmutase: 4-phosphate o-acetylserine methyltransferase: mycofactocin system adenosyltransferase: a,c-diamide [small subunit of cyclic prenyltransferase: glycosylase/ ON20_RS23985 ON20_RS17820 map map deacylase: trehalose- synthetase 2+ 2+ precorrin-6B ON20_RS22905 (1R,6R)-6-hydroxy-2- oleate β-oxidation 5-hydroxy-CTP 5-hydroxy-CMP ON20_RS20830 ON20_RS27420 uracil-DNA 3-ketosteroid-9- catalase/ Mg RS20305 Mg glycosyltransferase: (2Fe-2S)] complex cobH ON20_RS05445 adenosyltransferase: molybdopterin pyranopterin NADH DNA-(apurinic or sulfhydrylase: ON20_RS04260 phosphatase: TilS: tilS succinylcyclohexa-2,4- ON20_RS13270 cystathionine cysteine glycosylase: [+ 2 isozymes] alpha-hydroxylase [+ 2 isozymes] peroxidase cobalt-precorrin- synthase] phosphate apyrimidinic site) ON20_RS30675 methylated-DNA-- FMN-dependent trehalose-otsB mftF hydrogenobyrinate menaquinol-11 diene-1-carboxylate cob(I)yrinic acid ON20_RS05445 gamma-synthase: desulfurase: subunit A: 6B (C 15 )- (2E,6E)-farnesyl oleate NADH- ON20_RS17540 HPI: katG trans-methoxy- 4-phospho- lyase: ON20_RS17465 cysteine [protein]-cysteine S- ON20_RS15480 34 MMFT-4 O-succinylbenzoate a,c-diamide cob(I)yrinic acid ON20_RS21040 an N-terminal L- 9α-hydroxy-ON20_RS01930 an N-terminal a lysidine methyltransferase molybdopterin diphosphate 5-oxo-L-proline metabolism azoreductase: Ala mono-mycolate D-erythronate synthase: cysM methyltransferase: a tRNA gly Ile2 Peptide RS03865 Peptide synthase: adenosyltransferase: a,c-diamide acyl-CoA ON20_RS12145 met threonyl-[protein] androst-4- met L-seryl-[protein] in tRNA [decarboxylating]: a [chaperone- synthase: Amine and Polyamine 2,6-diamino-4- ON20_RS24035 an apyrimidinic uracil mycofactocin system an [2Fe-2S] ON20_RS24860 cobO adenosyltransferase: a [protein] with synthetase: a 5'-phospho- a 3'-phospho- a [ThiI sulfur- en-3-one-17- A H O ON20_RS13690 ADP]-[disordered- ON20_RS18220 Degradation hydroxy-5-(N-methyl) 4-oxo-2-pentenal succinate site in DNA 2 glycosyltransferase: cluster protein cobO an N-terminal ON20_RS05895 [DNA] [DNA] L-homocysteine ala carrier protein]- propanoyl-CoA form scaffold hydrogenobyrinate 2-succinylbenzoate adenosylcobinamide acetate L-selenocysteine mftF cobalt-precorrin-7 tetrahydrofolate salvage from a [protein] with Detoxification formamidopyrimidine a [protein]-S- N,N-dimethyl-1,4- S-sulfanyl- Peptide RS18020 Peptide protein] complex a,c-diamide (3R)-3-hydroxy-2-oxo- adenosylcobalamin L-glutamine [+ 11 isozymes] ethanolamine utilization a thymine in DNA anthranilate D-glyceraldehyde o-succinylbenzoate- molybdopterin 5,10-methenyltetrahydrofolate an N-terminal methyl-L-cysteine phenylenediamine L-cysteine MMFT-5 cobaltochelatase 4 phosphooxybutanoate pyruvate bifunctional bifunctional cobalt- 3-phosphate -CoA ligase: L-glutamate glutaminyl-peptide oleoyl-CoA subunit CobN: phosphoserine adenosylcobinamide molybdopterin a 5,10- ethanolamine reactive oxygen species degradation mycofactocin system precorrin-7 (C(5))- ON20_RS22960 cyclotransferase: ON20_RS13405 transaminase: kinase/ adenylyltransferase: methenyltetrahydrofolate a 7,8-dihydro- quinoxaline-2- a 3-methyl- an N-formyl-L- a guanine 34 3-oxo-23,24- an N-terminal- a peptide with a protein RS06715 a protein methyltransferase/ an [Fe-S cluster bifunctional 5,10- ON20_RS02810 acyl-CoA 2-oxoglutarate an unsulfurated preQ D-glycero-β-D- a D-tryptophanyl- a D-aspartyl- methylglyoxal glycosyltransferase: ON20_RS02870 1-deoxy-D- 4-(2'-carboxyphenyl) adenosylcobinamide- 8-oxoguanine aryl-carrier protein branched methionylaminoacyl- cys 1 bisnorchol- L-methionyl-L- an N-terminal a protein cob(II)yrinate ON20_RS18215 dehydrogenase: superoxide carboxyl adenylate in tRNA [tRNA Trp ] [tRNA asp ] cobalt-precorrin- biosynthesis folate transformations III (E. coli) methylenetetrahydrofolate [sulfur carrier] ATP manno-heptose mftF a,c-diamide 4-phosphooxy- xylulose-5- -4-oxobutyryl-CoA phosphate molybdopterin in DNA 2,3,4-saturated tRNA 4-en-22-oate valyl-[protein] L-methionine glyoxalase/ zinc-dependent 6B (C(15))- chaperone]-ATP thiamine diphosphate salvage II dehydrogenase/5,10- a [protein] with ON20_RS10075 1-phosphate 3-ketosteroid-9- phosphate guanylyltransferase: adenine γ-L-glutamyl superoxide dismutase: fatty acyl-CoA bleomycin metalloprotease: MMFT-6 methyltransferase: L-threonine 1,4-dihydroxy- methenyltetrahydrofolate an N-terminal 5- [+ 55 isozymes] tRNA alpha-hydroxylase synthase: ON20_RS08485 5-phosphate glutathione acetaldehyde ON20_RS00245 resistance/ sulfate RS13655 sulfate ON20_RS13690 a tetrahydrofolate 2-naphthoyl- NAD de novo biosynthesis 4-amino-2-methyl-5- dinucleotide cyclohydrolase: oxo-L-proline bifunctional DNA- acyl carrier phytanoyl-CoA peptide cysteine D-tyrosyl- subunit A: type I methionyl D-tyrosyl- type I methionyl ON20_RS19415 dxs (2E,9Z)- guanosine(34) D-glycero-beta-D- dioxygenase mycofactocin system CoA synthase: I (from aspartate) adenosyl-cobinamide pyrimidinemethanol molybdopterin ON20_RS11035 superoxide dismutase: formamidopyrimidine protein: dioxygenase: deformylase: desulfurase: tRNA(Tyr) ON20_RS14500 aminopeptidase: tRNA(Tyr) aminopeptidase: zinc-dependent 10 octadecenoyl-CoA transglycosylase glycosyltransferase: cobalt-precorrin-8 ON20_RS22970 phosphate molybdotransferase an N - ON20_RS23665 glycosylase/ ON20_RS14105 ON20_RS26920 def ON20_RS17820 manno-heptose deacylase: map deacylase: map family protein: di-trans,poly-cis 3-amino-1- 1-deoxy-D- bifunctional hypothetical acetaldehyde bifunctional Tgt: 3-ketosteroid-9- metalloprotease: mftF MoeA: formyltetrahydrofolate DNA-(apurinic or 1-phosphate ON20_RS04260 ON20_RS04260 ON20_RS10435 -undecaprenyl methionine synthase: hydroxyacetone 1,4-dihydroxy-2- asp hydroxymethylpyrimidine protein: dehydrogenase acetaldehyde- [+ 5 isozymes] phytanoyl-CoA peptide cysteine ON20_RS00945 alpha-hydroxylase [+ 2 isozymes] [+ 2 isozymes] ON20_RS01425 predicted xylulose 5- bifunctional ON20_RS18210 phosphoribosylglycinamide hydrogen peroxide adenylyltransferase: [+ 9 isozymes] naphthoyl-CoA L-aspartate kinase/ apyrimidinic site) dioxygenase: deformylase: desulfurase: a peptide ABC MMFT-7 phosphate biosynthesis ON20_RS17810 1-phosphate phosphate adenosylcobinamide protein Pupylation 5-oxo-L-proline ON20_RS17965 (acetylating): CoA/alcohol rfaE2 subunit A: sulfate sulfate oxidase: phosphomethylpyrimidine molybdopterin formyltransferase: lyase: ON20_RS17465 ON20_RS23680 (R)-lactate transporter (2E,6E)-farnesyl methionine synthase: metH kinase/ and dePupylation [+ 2 isozymes] ON20_RS01845 dehydrogenase: a quinoxaline-2- ON20_RS32620 ON20_RS15480 a 7-aminomethyl-7- 3-one-9-hydroxy-ON20_RS01930 an N-terminal IPP ON20_RS21745 catalase/peroxidase Trp asp mycofactocin system diphosphate ON20_RS09080 kinase: thiD molybdotransferase ON20_RS09525 carboxyl-[aryl- 34 D-tryptophan a tRNA met tRNA D-aspartate met a peptide of sulfate cobyrinate adenosylcobinamide- a [prokaryotic 5-oxoprolinase: (S)-3-hydroxy-(9Z) [+ 2 isozymes] AMP a 2-hydroxy-3- deazaguanosine β 23,24-bisnorchol- L-valyl-[protein] glycosyltransferase: 2-iminosuccinate MoeA: HPI: katG carrier protein] guanine ADP-D-glycero- - phosphate a tetrahydrofolate Fatty Acid and Lipid Biosynthesis ON20_RS25380 -octadecenoyl-CoA a 5'-phospho- a 3'-phospho- 7,8-dihydro- methyl-branched succinate in tRNA 4-en-22-oate mftF dihydrofolate reductase: 1,4-dihydroxy- HMP-P ON20_RS21600 ubiquitin-like protein] [+ 2 isozymes] 4-oxo-2-pentenal formate a L-methionylaminoacyl- a sulfurated D-manno-heptose sulfite RS01125 sulfite cobyrinate A,C- isoprenyl pyridoxine adeninyl adenosylcobamide quinolinate guanylyltransferase: H O hydroxyl radical [DNA] [DNA] 8-oxoguanine 2,3,4-saturated ala ON20_RS26480 2-naphthoate MoO - C-terminal L-glutaminePup 3-hydroxyacyl-CoA acetyl-CoA ethanol 2 tRNA [sulfur carrier] diamide synthase: biosynthesis from 2 MMFT-8 transferase: [+ 3 isozymes] 5'-phosphate synthase NadA: ON20_RS08485 5-(2-hydroxyethyl) bifunctional molybdopterin palmitate biosynthesis II deamidase: glu dehydrogenase: fatty acyl-CoA ON20_RS17095 ON20_RS20965 serine glycine cleavage system adenosylcobinamide-GDP ON20_RS09085 -4-methylthiazole hydroxymethylpyrimidine phosphatidylinositol mannoside biosynthesis biotin-carboxyl carrier protein assembly a [prokaryotic Pentose Phosphate Pathways phosphate O pyridoxamine adenosylcobinamide- cofactor (bacteria and plant cytoplasm) pafA ON20_RS01050 2 mycofactocin system cob(II)yrinate isoprenyl a 7,8-dihydrofolate hydroxymethyltransferase:protein GcvH: agcvH 5-methyltetrahydrofolate GDP kinase/ ubiquitin-like protein] acetyltransferase: α sulfite RS11790 sulfite 5'-phosphate quinolinate a [biotin carboxyl- 3-oxo-(9Z)- a CDP- β-D-glucose DNA with adenine:7,8- acibenzolar- an N-terminal- (2Z)-2- L-malic cholest-4- 6-O- -mycolyl- glycosyltransferase: a,c-diamide transferase: ON20_RS20945 [+ 2 isozymes] adenine phosphomethylpyrimidine a 1-phosphatidyl- C-terminal L-glutamate pentose phosphate pathway ON20_RS23970 Reactive Blue 5 sn-glycerol a holo-[VibB aryl- an oxidized oxaloacetate phosphoenol oxidase: an acetoacetyl-[acp] octadecenoyl-CoA diacylglycerol 2,3- glu a (6S)-5- dihydro-8- L-methionyl- hydroxypenta- semialdehyde en-3-one trehalose 6- mftF nicotinate-nucleotide-- kinase: thiD 1D-myo-inositol carrier protein]-L-lysine 3-phosphate carrier protein] factor 420 6-phosphate ITP S-methyl dGDP pyruvate ON20_RS07590 ON20_RS18325 carboxylating 4-methyl-5-(2- Pup--protein 3-ketoacyl- dihydroxybenzoate formyltetrahydrofolate oxoguanine mismatch glycyl-[protein] 2,4-dienoate aldehyde 3-ketosteroid- phosphate biotin--[acetyl-CoA- D-glucopyranose acetyl phosphate 2-keto-4- trehalose- thymidylate synthase: dimethylbenzimidazole nicotinate- phosphooxyethyl) NAD salvage pathway I (PNC VI cycle) beta-ketoacyl- phosphatidylinositol 2- ligase: pafA lipoprotein posttranslational modification dehydrogenase delta-1- MMFT-9 [+ 4 isozymes] HMP-PP α carboxylase] ligase: CoA thiolase: phosphatase: di-trans,octa-cis ON20_RS21840 phosphoribosyltransferase: -mannosyltransferase: N6-([prokaryotic 6-phosphate Dyp-type glucose-6- carboxylesterase/ pentenoate nucleotide 5-methylbenzimidazolyl thiazole ACP reductase: ON20_RS05090 ON20_RS30060 acetate kinase: CDP-diacylglycerol-- 2,3- A/G-specific type I methionyl (NADP(+)): dehydrogenase: -undecaprenyl cobT ON20_RS16165 a [prolipoprotein]- glucose-6- peroxidase: bifunctional phosphate lipase family hydratase: otsB PLP diphosphorylase: adenosylcobamide biosynthesis + ON20_RS15195 ubiquitin-like protein]- glycerol-3-phosphate 3- phosphoenolpyruvate ON20_RS31920 ON20_RS14425 biotin biosynthesis from diphosphate bifunctional 5,10- adenine ribotide NAD a 2-O-(α-D-mannosyl) a [biotin carboxyl-carrier L-cysteine ON20_RS23965 dihydroxybenzoate- folylpolyglutamate adenine pyruvate aminopeptidase: ON20_RS13960 a (6S)-5-formyltetrahydrofolate ON20_RS09075 from adenosylcobinamide-GDP thiamine a (3R)-3- γ-L-glutamyl)- phosphate (7Z)-hexadecenoyl-CoA ON20_RS28525 dehydrogenase carboxykinase (GTP) protein: trehalose- 8-amino-7-oxononanoate I undecaprenyl- phosphate 6 phosphatidyltransferase: AMP ligase: entE synthase/ glycosylase: kinase: pyk map aldehyde 3-oxosteroid 1- methylenetetrahydrofolate phosphate NAD+ synthetase, hydroxybutanoyl- -1-phosphatidyl- protein]-N -biotinyl-L-lysine [protein]-L-lysine prolipoprotein dehydrogenase: Dyp-type (coenzyme- : ON20_RS24675 ON20_RS28445 2-keto-4- phosphatase: 5-methylbenzimidazole acetate pgsA dihydrofolate ON20_RS01665 [+ 2 isozymes] dehydrogenase dehydrogenase: 8-amino-7- diphosphate dehydrogenase/5,10- 5-formyltetrahydrofolate NaMN glutamine NAD(+) [acp] 1D-myo-inositol diacylglyceryl ON20_RS15555 acyl-CoA peroxidase: 2,3- F420): fgd [+ 2 isozymes] pentenoate otsB adenosylcobinamide- synthase: (NADP(+)): ON20_RS01830 α α phosphatase: methenyltetrahydrofolate nicotinate-nucleotide-- dependent: diphosphatase: transferase: 6-phospho dehydrogenase: dihydroxybenzoate- synthase: , '-trehalose oxononanoate cyclo-ligase: GDP ON20_RS23915 ammonia-dependent Degradation/Utilization/Assimilation - Other ON20_RS21825 hydratase: cholest- α adenosylmethionine- ON20_RS22035 dimethylbenzimidazole ON20_RS18195 ON20_RS10075 CMP 1-(3-sn- AMP ligase: entE ON20_RS06925 ON20_RS07855 6- -mycolate cyclohydrolase: ON20_RS21610 thiamine diphosphate ribazoletransferase: NAD(+) synthetase: ON20_RS19420 ON20_RS34200 D-glucono- 6-phospho phosphoenolpyruvate an apurinic site pyruvate an N-terminal ON20_RS01840 dien-3-one -8-amino-7- ON20_RS11035 phosphoribosyltransferase: a [biotin carboxyl-carrier-protein a [prokaryotic a [prolipoprotein]- [+ 55 isozymes] phosphatidyl) a reduced IDP dGTP (S)-4-hydroxy- (S)-malate undecaprenyl- biosynthesis I (E. coli) ON20_RS08470 ON20_RS18195 1,5-lactone 3-[(4-amino-6-chloro- D-glucono- adenine within DNA acibenzolar MeOH met glycyl-[protein] oxononanoate thiamine 6 ubiquitin-like protein] octane oxidation 2,2'-disulfonyl -sn-glycerol factor 420 2-oxopentanoate a 5,10-methylenetetrahydrofolate a 5,10-methenyltetrahydrofolate Coα-[α-(adenin- cobT nicotinate adenine dinucleotide NMN a (2E)-but- phosphatidylinositol dimer]-N -biotinyl-L-lysine S-1,2-diacyl-sn- (2E,7Z)- thiocyanate phthalate a 2,3- transaminase: diphosphate 2-[(2R,5Z)- nicotinate adenine 5-methylbenzimidazole phosphate C-terminal L-glutamate 6-phosphogluconolactonase: 1,3,5-triazin-2-yl) 3-phosphate a (6S)-5- 1,5-lactone 9-yl)]-Coβ- mannoside acetyl-CoA glyceryl-L-cysteine azobenzene dihydroxybenzoyl- ON20_RS08975 phosphatase: bifunctional 5,10- 2-carboxy-4- dinucleotide ribotide phosphate 2-enoyl-[acp] pgl hexadecenoyl-CoA degradation II amino]benzenesulfonate formyltetrahydrofolate adenosylcobamide thiamine- acyltransferase: carboxylase: biotin carboxylase: NADH [VibB] 7,8- ON20_RS13160 methylenetetrahydrofolate methylthiazol-5(2H ammonia- enoyl-ACP D-gluconate hypothetical di-trans,octa-cis 5'-phosphate NAD+ synthetase, adenosylcobinamide- phosphate kinase: ON20_RS31135 signal peptidase diaminopelargonate benzimidazolyl adenosylcobamide reductase FabI: ON20_RS10340 ON20_RS05485 protein: thiocyanate dehydrogenase/5,10- HMP-PP )-ylidene]ethyl dependent GDP ON20_RS17545 II: ON20_RS08865 6-phosphate ATP-dependent -undecaprenyl biosynthesis from glutamine phosphatidylinositol [+ 4 isozymes] ON20_RS17965 thiocyanate adenosylcobalamin biosynthesis thiamine diphosphate methenyltetrahydrofolate phosphate NAD(+) ribazoletransferase: ON20_RS15190 5-amino-5-(4- 7,8-didemethyl- 3-[(R)-glyceryl]- 7,8-didemethyl- enolpyruvoyl- DNA combined phosphoenol (2Z)-2- 6-O-cis-methoxy- phosphate dependent: thiamine mannoside decarboxylating 6- hydrolase 2-oxoglutarate phytanoyl-CoA H O a carboxylic ester a D-tyrosyl- dethiobiotin from adenosylcobinamide-GDP I cyclohydrolase: adenosylcobinamide-GDP synthetase: a [carboxyl-carrier protein dimer]- an (S-diacyl-sn- [+ 2 isozymes] hydroxybenzyl)- SAM 8-hydroxy-5- diphospho- 8-hydroxy-5- 2-diphospho- acyl-carrier protein a long-chain with exogenous 2 hydroxyhexa- glu ala mycolyl-trehalose 3',5'-ADP biosynthesis III α α ON20_RS08470 a lipoprotein phosphogluconate ATP dADP pyruvate [tRNA Tyr ] Co -[ -(adenin- ON20_RS18195 diphosphate a butanoyl-[acp] acyltransferase: 6 subunit fatty acid synthetase BioD: (Staphylococcus) ON20_RS11035 thiamine benzimidazole ON20_RS18195 Coα-[α-(5- NaMN nicotinamide N -carboxybiotinyl-L-lysine glyceryl)-L-cysteinyl- signal peptide (S)-3-hydroxy-(7Z) a reduced 6-(D-ribitylimino) deazariboflavin 5'-guanosine deazariboflavin 5'-guanosine DNA to form a 2,5-dienoate 6-phosphate 3'(2'),5'- 7-yl)]-Coβ- ON20_RS16170 dehydrogenase: gnd octane gamma: scnC 2-keto-4- trehalose- ON20_RS08995 5,6-dimethylbenzimidazole 2-(2-carboxy-4- phosphate methylbenzimidazolyl)]- nicotinamidase: [apolipoprotein] -hexadecenoyl-CoA rubredoxin -5,6-dihydrouracil recombinational bisphosphate nicotinate-nucleotide-- + α phosphatase: 10 adenosylcobamide beta-ketoacyl- a 2,6-di-O-( - [+ 2 isozymes] carbonyl sulfide phytanoyl-CoA Holliday junction carboxylesterase/ pentenoate nicotinate-nucleotide-- methylthiazol-5- an N -formyltetrahydrofolate synthase: NAD Coβ-adenosylcobamide ON20_RS05570 junction nucleotidase dethiobiotin 5,6-dimethylbenzimidazole dimethylbenzimidazole D-mannosyl)-1- apolipoprotein N- D-ribulose 3-hydroxyacyl-CoA 2-phospho- 2-phospho- long-chain- resolvase RuvX: ATPase: D-tyrosyl- hydratase: glutamate-- otsB dimethylbenzimidazole yl)ethyl phosphatethiamine ON20_RS23915 ACP synthase II: dioxygenase: lipase family biosynthesis I (aerobic) phosphoribosyltransferase: 5'-phosphate acyltransferase: lnt dehydrogenase: alkane 1- 7,8-didemethyl- L-lactate L-lactate fatty acid--ACP ON20_RS15880 ON20_RS18480 pyruvate tRNA(Tyr) cysteine ligase: CysQ: phosphoribosyltransferase: phosphate nicotinate ON20_RS23770 phosphatidyl- 5-phosphate ON20_RS32620 protein: ON20_RS13960 trehalose- biotin cobT 1D-myo-inositol a 2-O-(6-O-acyl- an N-acyl-(S-diacyl- ON20_RS01050 monooxygenase: 8-hydroxy-5- transferase: transferase: ligase MbtM: ATPase: kinase: pyk deacylase: ON20_RS22095 phosphatase: ON20_RS11550 cobT synthase: benzimidazole folate polyglutamylation phosphoribosyltransferase: a 3-oxohexanoyl- phosphatidylcholine a peptide phytanoyl-CoA crossover junction ON20_RS28445 2-keto-4- synthase BioB: riboflavin α-ribazole thiamine α-D-mannosyl)- sn-glyceryl)-L- 3-oxo-(7Z)- ON20_RS19805 deazariboflavin ON20_RS19840 ON20_RS19840 ON20_RS14115 ON20_RS04650 ON20_RS04260 [+ 2 isozymes] ON20_RS23915 ribotide phosphate ON20_RS05575 biosynthesis VI ribulose- ribose-5- dioxygenase: resolution of endodeoxyribonuclease [+ 2 isozymes] pentenoate trehalose-otsB ON20_RS09045 bifunctional thiamine phosphate factor 420 α α [acp] cysteinyl-[lipoprotein] hydrogen sulfide synthase: fbiC AMP 5'-phosphate menaquinol-10 biosynthesis glutathione Co -[ -(5- nicotinate phosphatidylinositol 1-phosphatidyl- phosphate 3- phosphate hexadecenoyl-CoA alkane 1- recombinationalRuvC: ON20_RS16110 cis-methoxy- polyglutamylation a CDP- ON20_RS26920 hydratase: riboflavin kinase/ phosphate thiamine- adenosylcobinamide- biosynthesis methylbenzimidazolyl)]- a tetrahydrofolate beta-ketoacyl- dimannoside 1D-myo-inositol monooxygenase: + biotin adenosylcobinamide- NAD choline epimerase: isomerase: 3-ketoacyl- oxidized 3PG- dehydro a long-chain junction phosphate H pyruvate ON20_RS01840 γ-L-glutamyl- mono-mycolate FAD synthetase: ribF all-trans- phosphate kinase: oxidized GDP Coβ-adenosylcobamide ACP reductase: acyltransferase: diacylglycerol ON20_RS19825 7,8-didemethyl- ADP dATP a tRNA Tyr (S)-4-hydroxy- GDP thioredoxin phosphorylation and rpe ON20_RS06575 CoA thiolase: factor 420-0 GMP factor 420-0 GMP fatty acyl-[acyl- formation of two an alcohol a carboxylate D-tyrosine D-alanine FMN decaprenyl 1,4-dihydroxy- ribazoletransferase: 5'-deoxyadenosine 2-hydroxyphytanoyl- ON20_RS17545 factor 420-0 cys glu transhydrogenation ON20_RS15195 ON20_RS31135 ON20_RS30060 8-hydroxy-5- met carrier protein] intact strands 2-oxohexanoate ribazoletransferase: 2-naphthoate pathway coenzyme bifunctional serine 6 37 ribose-5- succinate diphosphate ON20_RS08470 a (3R)-3- phosphatidylcholine/ N -L-threonylcarbamoyladenosine D-xylulose deazariboflavin CoA flavin reductase: ON20_RS08470 thiamine F420-0:L- Coα-[α-(benzimidazolyl) folylpolyglutamate hydroxymethyltransferase: NAD + phosphate 1-octanol hydroxyhexanoyl- a 2-O-(6-O-acyl- phosphatidylserine -modified tRNA biosynthesis 5-phosphate (5Z)-tetradecenoyl-CoA thiamine an oxidized 10 isomerase RpiA: acrylonitrile ON20_RS28490 adenosylcobalamin 1,4-dihydroxy- diphosphate glutamate ligase: ]-Coβ-adenosylcobamide an N - synthase/ ON20_RS20945 NAD kinase: [acp] α synthase: thioredoxin glutamate-- -D-mannosyl)-6- degradation I lipoate biosynthesis flavin reductase: 5'-phosphate 2-naphthoate ON20_RS19835 5'-phosphate formyltetrahydrofolate dihydrofolate ON20_RS09850 α ON20_RS23585 ON20_RS31925 acyl-CoA an L-1- 7,8-didemethyl- (2S)-lactyl-2- an NDP-α- a peptidoglycan an N-terminal- 38- 3-oxo-4- 6-O-trans-keto- thiamine oxidized cysteine ligase: O-( -D-mannosyl) an L-lysyl- a ferrocytochrome 3-phospho- methyl (indol- a uridine (3E)-5-chloro-2- maleate and incorporation I synthase: a 5,10- + ATP dehydrogenase: phosphatidyl- palmitoyl-CoA 8-hydroxy-5- diphospho- methylsalicylate ON20_RS30125 polyprenyltransferase: NADP thr Lys D-glucose 3-yl)acetate dimer (generic) L-methionyl-L- 40 in tRNA oxopent-3-enoate ala UDP-N-acetyl- pregnene-20- mycolyl-trehalose pyrophosphokinase: factor 420-1 ON20_RS22095 bifunctional -1-phosphatidyl- acrylonitrile [tRNA ] b (R)-glycerate ON20_RS06925 methylenetetrahydrofolate D-ribose 5- ON20_RS10195 sn-glycerol 5 deazariboflavin 5'-guanosine cysteinyl-[protein] RluA family 2-keto-4- α carboxyl-CoA 6-phosphate maleate cis- ON20_RS23000 F420-1:γ- folylpolyglutamate 1D-myo-inositol -D-muramate 3-ketosteroid- trehalose- FMNH ON20_RS09865 thioredoxin- [+ 2 isozymes] a phosphatidylcholine phosphate 1-octanal nitrile hydratase an octanoyl-[acp] 2 bifunctional NAD(P) a (2E)-hex- [+ 55 isozymes] pseudouridine pentenoate phosphatase: trans isomerase: thiamine disulfide glutamyl ligase: Coα-[α-(benzimidazolyl) synthase/ trans,octacis- subunit beta: glucosyl-3- carboxylesterase/ endolytic carboxylesterase/ delta-1- lipoyl(octanoyl) folylpolyglutamate transhydrogenase 2-enoyl-[acp] threonylcarbamoyl- (2E,5Z)- bifunctional acyl-CoA 2-phospho- type I methionyl synthase: hydratase: otsB ON20_RS10230 5,6-dimethylbenzimidazole adenosylcobalamin diphosphate DMKH2-10 reductase: ON20_RS19835 ]-Coβ-adenosylcobamide γ-L-glutamyl- dihydrofolate a tetrahydrofolate decaprenyl phosphate transketolase: ON20_RS24640 phosphoglycerate lipase family transglycosylase lipase family UDP-N- dehydrogenase: transferase LipB: synthase/ subunit alpha: AMP synthase: tetradecenoyl-CoA lysylphosphatidylglycerol desaturase: L-lactate ON20_RS08860 ON20_RS13960 maleate cis- synthase: bluB trxB oxidized L-cysteine synthase: enoyl-ACP α ON20_RS15545 acrylamide synthase: protein: MltG: aminopeptidase: protein: acetylmuramate-- ON20_RS14425 trehalose- ON20_RS29605 demethylmenaquinone dihydrofolate ON20_RS05175 a 2-O-(6-O-acyl- - polyprenol ON20_RS05385 synthetase/lysine-- ON20_RS15085 transferase: tRNA 2-keto-4- trans isomerase: a [lipoyl-carrier protein] factor 420-2 ON20_RS06925 reductase FabI: α ON20_RS20415 ON20_RS28445 ON20_RS15875 map ON20_RS28445 L-alanine ligase: 3-oxosteroid 1- phosphatase: synthase: D-mannosyl)-6-O-[ - monophosphomannose D-sedoheptulose D-glyceraldehyde ∆ 3 ∆ 2 ON20_RS16905 6 5,6-dimethylbenzimidazole methyltransferase: 10 -cis- -trans- enoyl-CoA octanoate amidase: tRNA ligase LysX: [+ 3 isozymes] ON20_RS19840 [+ 2 isozymes] pseudouridine(38- pentenoate ON20_RS08765 N -octanoyl-L-lysine an N - NADPH ON20_RS15190 D-mannosyl-(1->6) 7-phosphate 3-phosphate [+ 2 isozymes] [+ 3 isozymes] [+ 2 isozymes] dehydrogenase: trehalose-otsB ON20_RS22905 ON20_RS06925 synthase: ON20_RS02690 (L-threonylcarbamoyl) enoyl-CoA hydratase: ON20_RS11935 ON20_RS00165 40) synthase TruA: hydratase: fumarate a reduced formyltetrahydrofolate α α 3-oxo-23,24-ON20_RS01830 trans-keto- lipoyl pyridoxal 5'-phosphate biosynthesis II demethylmenaquinol- - -D-mannosyl]- trans,octacis- adenylate isomerase: ON20_RS02970 2-O-( -D- ON20_RS04320 ON20_RS01840 demethylmenaquinol- thioredoxin demethylmenaquinol- a 5,10- a hexanoyl-[acp] acyl-CoA [+ 4 isozymes] a nucleoside UDP-N-acetyl- mono-mycolate synthase: lipA menaquinol-10 8 biosynthesis I glutathione 1-phosphatidyl- decaprenylphospho- transaldolase: tal oxidized glucopyranosyl) GlcNAc-1,6- an N-terminal L- a pseudouridine 38- 5-chloro-4-hydroxy- bisnorchol-1,4- 9 biosynthesis 6 biosynthesis I methylenetetrahydrofolate tRNA (adenosine(37)-N6)- ON20_RS30065 [+ 2 isozymes] synthetase: palmitoleoyl-CoA a ferricytochrome diphosphate a lipid II α 1D-myo-inositol β-D-mannose transaldolase: tal acrylate 3-O-L-lysyl-1-O- factor 420-0 GMP -3-phospho- (indol-3-yl)acetate MeOH anhydro-MurNAc- met cysteinyl-[protein] salicylate MeOH -D-muramoyl- dien-22-yl-CoA a [lipoyl-carrier all-trans- beta-ketoacyl- ON20_RS05895 Lys b 40 in tRNA 2-oxopentanoate threonylcarbamoyltransferase a tRNA 5 6 aldehydo-D-ribose D-glyceraldehyde gln all-trans- all-trans- phosphatidylglycerol pentapeptide L-alanine protein]-N -[(R)- 1,4-dihydroxy- octaprenyl ACP synthase II: complex: tsaD tsaB (3E,5Z)-tetradeca- (S)-3-hydroxy-(5Z) [+ 11 isozymes] D-glycerate thiamine diphosphate 5-phosphate 3-phosphate nonaprenyl 1,4-dihydroxy- hexaprenyl 1,4-dihydroxy- D-erythrose dihydrolipoyl]-L-lysine 2-naphthoate diphosphate ON20_RS23770 ON20_RS21195 F6P 3,5-dienoyl-CoA -tetradecenoyl-CoA salvage III diphosphate 2-naphthoate diphosphate 2-naphthoate 4-phosphate acyl carrier an N 6 -L- a 3-oxooctanoyl- 3-hydroxyacyl-CoA AMP α pyridoxal 5'- menaquinol-9 biosynthesis 1,4-dihydroxy- menaquinol-6 biosynthesis a 2-O-(6-O-acyl-α-D- 37 UDP-N-acetyl- -D-muramoyl- sn-glycero-3- a peptide with a mycothiol 6-O-cis-keto- cholest-5- protein activation threonylcarbamoyladenine transketolase: a [DNA]-3'- + a 5'-phospho- 3-phospho- α all-trans- thiamine 1,4-dihydroxy- 1,4-dihydroxy- [acp] dehydrogenase: γ NAD ADP- -D-glucose succinate H O an L-cysteinyl- phosphate mannosyl)-6-O-[α-D- L-alanyl- -D-glutamyl- phospho-N- acyl-carrier protein an N-terminal 2 L-saccharopine mycolyl-trehalose thiamine 2-naphthoate in tRNA ON20_RS15545 ON20_RS01050 D-alanyl-D-alanine hydroxyl [DNA] (R)-glycerate myristate GTP retinyl palmitate S-conjugate [tRNA Pro ] en-3-one synthase: 2-naphthoate 2-naphthoate mannosyl-(1->6)-α- meso-2,6-diaminopimelate (arachidonoyl) L-proline 6-phosphate steroid Delta- an apo acyl- pyrophosphokinase: demethylmenaquinol-9 polyprenyltransferase: demethylmenaquinol-6 beta-ketoacyl- D-glyceraldehyde (3E,5Z)- trehalose- ON20_RS16140 polyprenyltransferase: polyprenyltransferase: Aromatic Compound Biosynthesis D-mannosyl-(1->6) 3-oxo-(5Z)- ethanolamine isomerase: carrier proteinholo-ACP ON20_RS09865 demethylmenaquinone ON20_RS23000 demethylmenaquinone ACP reductase: Glycolysis 3-phosphate tetradecadienoate ADP-forming mycothiol phosphatase: thiamine ON20_RS16155 ON20_RS23000 ON20_RS23000 α tetradecenoyl-CoA ATP-dependent glucosyl-3- carboxylesterase/ ON20_RS14495 methyltransferase: methyltransferase: ON20_RS15195 - -D-mannosyl]- UDP-N- long-chain- prolyl saccharopine Cys-tRNA(Pro) otsB synthase: a (3R)-3- CDP-diacylglycerol DNA ligase: phosphoglycerate succinate--CoA ligase: GTPase lipase family conjugate diphosphate ON20_RS22905 ON20_RS22905 chorismate biosynthesis I 1-phosphatidyl- 3-ketoacyl- acetylmuramoyl- glycerophosphodiester fatty acid--ACP aminopeptidase: pip dehydrogenase: deacylase: steroid Delta- ON20_RS06240 demethylmenaquinol-8 biosynthesis I glycolysis I (from glucose 6-phosphate) ON20_RS12030 synthase: ON20_RS21760 HflX: hflX protein: amidase trehalose- a holo acyl- demethylmenaquinol-9 menaquinol-9 demethylmenaquinol-6 menaquinol-6 dipicolinate biosynthesis hydroxyoctanoyl- 1D-myo-inositol CoA thiolase: tripeptide--D-alanyl- phosphodiesterase: ON20_RS03470 ON20_RS19605 isomerase: PLP ON20_RS21765 ligase MbtM: prolyl [+ 5 isozymes] Mca: mca phosphatase: carrier protein D-erythrose [acp] ON20_RS21060 [+ 4 isozymes] ON20_RS20415 ON20_RS28445 ON20_RS06875 DHAP D-glucopyranose D- alanine ligase: ON20_RS00265 ON20_RS14115 aminopeptidase: pip otsB 4-phosphate Respiration (3Z)-dodec- [+ 2 isozymes] cholest-4- 3-deoxy-7- asp glycerol-3- 6-phosphate ON20_RS08740 trehalose-cis-keto- 2-O-(α-D- H + en-3-one 3-enoyl-CoA phosphate allysine a tRNA Pro mono-mycolate phosphoheptulonate a 2-O-(6-O-acyl-α-D- phosphate [DNA] NMN phosphate succinyl-CoA GDP GlcN-Ins a mercapturate glu cys aspartate kinase: glucose-6- ∆3,∆2-enoyl- glucopyranosyl) ADP anandamide sn-glycerol synthase: mannosyl)-6-O-[α-D- dehydrogenase: 2-oxoisovalerate decarboxylation UDP-N-acetyl-α-D-muramoyl-L- AMP ADP a myristoyl-[acp] a peptide pro palmitate a retinol ON20_RS01150 a (2E)-oct- phosphate CoA isomerase: Carbohydrate Degradation -3-phospho- 3-phosphate Carbohydrate Biosynthesis Nucleoside and Nucleotide Biosynthesis ON20_RS02725 mannosyl-(1->2)-α- ON20_RS17560 to isobutanoyl-CoA alanyl-γ-D-glutamyl-meso-2,6- L-aspartyl- 2-enoyl-[acp] sn-glycerol isomerase: ON20_RS17965 D-glycerate 3-deoxy-7- D-mannosyl-(1->6)- an [apo BCAA diaminopimeloyl-D-alanyl-D-alanine 4-phosphate enoyl-ACP 3-phosphate ON20_RS21790 D-galactose degradation I (Leloir pathway) α-D-mannosyl-(1->6) dehydrogenase (2E)-dodec- UDP-N-acetyl-D- superpathway of purine nucleotides de novo biosynthesis I phosphoheptulonate alpha-ketoacid D-mannose GDP-mannose biosynthesis UDP-α-D-glucose trehalose biosynthesis I superpathway of pyrimidine deoxyribonucleotides reductase FabI: α 6 2-enoyl-CoA glucosamine biosynthesis I superpathway of pyrimidine pyrimidine deoxyribonucleotides de novo biosynthesis I synthase class II: aspartate- - -D-mannosyl]- glycerol-3- E2 protein] N β-D- degradation an all-trans- a peptide with ON20_RS15190 F6P dehydrogenase a purine base (4S)-4-hydroxy-2- O-phospho- biosynthesis I ribonucleotides de novo biosynthesis adenosine nucleotides biosynthesis from CTP semialdehyde 1-phosphatidyl- phosphate 1-O- -lipoyl-L-lysine hypothetical a ferrocytochrome stearoyl-CoA 1,4-dihydroxy- 5'-deoxyadenosine campesterol acetyl-CoA 3-deoxy- ON20_RS08640 subunit beta: galactopyranose lesion in DNA aryl-carrier protein polyisoprenyl acyl-carrier protein palmitate oxoheptanedioate cys thr an N-terminal D-glucopyranose D-glucopyranose α PRPP de novo biosynthesis I UDP CTP dehydrogenase: acyltransferase: protein: D-mannopyranose 2,3-dihydroxybenzoate b ATP dITP L-homoserine D-glucopyranose UDP- -D-glucose D-glucopyranose 6-phosphate CTP 1D-myo-inositol 5 a tRNA precursor 2-naphthoate diphosphate L-alanine steroid Delta- acetyl-CoA 6-phosphate 6-phosphate D-arabino- an octanoyl-[acp] ON20_RS29105 6-phosphate threonine/serine glucose-6- glucose-6- class 1b ribonucleoside- ON20_RS01155 ON20_RS02700 class II fructose- ON20_RS17965 mannose-6- CTP non-canonical purine isomerase: 6-phosphate amidophosphoribosyltransferase: gln hydrogencarbonate heptulosonate 6-phosphofructokinase: carboxylase alpha-D-glucose IMP diphosphate a 1-acyl-sn bisphosphatase: alpha-ketoacid [+ 2 isozymes] bifunctional DNA- S-methyl-5'- NTP pyrophosphatase: HpcH/HpaI dehydratase: ON20_RS14495 phosphate phosphate ON20_RS02530 asp CDP 7-phosphate L-aspartate 4- beta-ketoacyl- ON20_RS17715 α-D- phosphate acyl-CoA long-chain- cystathionine biotin carboxyl phosphate-specific trehalose-6-phosphate reductase subunit -glycerol 3- glpX dehydrogenase formamidopyrimidine 2,3-dihydroxybenzoate- 1,4-dihydroxy- thioadenosine ON20_RS05625 aldolase/ ON20_RS06430 aminopeptidase isomerase: isomerase: semialdehyde ACP synthase II: (S)-3- isomerase, CCA tRNA gamma-synthase: steroid Delta- carrier phosphoglucomutase: synthase: ON20_RS02395 β 3-dehydroquinate a 2-O-(6-O-acyl-α-D- phosphate subunit beta: galactopyranose AMP ligase: entE desaturase: 2-naphthoate fatty acid--ACP phosphorylase: citrate lyase ON20_RS21790 ON20_RS21790 5-phospho- - gly CDP alpha: ON20_RS18170 class 1b ribonucleoside- class I: manA glycosylase/ nucleotidyltransferase: nucleoside triphosphate threonine N: pepN protein: accB glutamine- synthase: 4-hydroxy- ON20_RS23770 α fructose- β-D-fructose 1,6- dihydrolipoyl hydroxydodecanoyl-CoA ON20_RS15085 polyprenyltransferase: ligase MbtM: ON20_RS21040 isomerase: ON20_RS18770 D-ribosylamine class 1b ribonucleoside- mannosyl)-6-O-[ -D- 1-acyl-sn-glycerol- ON20_RS05225 F6P DNA-(apurinic or 2,3-dihydroxybenzoate- ON20_RS04350 family protein: ammonia- F6P F6P hydrolyzing adenylosuccinate diphosphate tetrahydrodipicolinate bisphosphate 3-hydroxyacyl-CoA galactokinase: ON20_RS25390 ON20_RS14115 pyrophosphohydrolase: ON20_RS06875 [+ 4 isozymes] α,α-trehalose 6-phosphate class 1b ON20_RS15855 a 3-oxodecanoyl- mannosyl-(1->2)-α- 3-phosphate bisphosphate dehydrogenase: apyrimidinic site) AMP ligase: entE [+ 3 isozymes] ON20_RS23000 ON20_RS24970 lyase IlvA: α-D-glucopyranose[+ 2 isozymes] carbamoyl- synthase: diphosphate reductase reductase subunit aldolase: an [apo BCAA an [apo BCAA dehydrogenase galK ON20_RS28640 campest- mannose-6- ribonucleoside- synthase: dapA [acp] D-mannosyl-(1->2)- acyltransferase: lpdA dehydrogenase: malonyl-CoA glutamine-- phosphoribosylamine- ON20_RS24065 subunit beta: nrdF alpha: ON20_RS18170 3-dehydroquinate dehydrogenase E2 protein] N 6 -S-[2- lyase: ON20_RS17465 ON20_RS08945 4-en-3β-ol 1-phosphate phosphate diphosphate (2S,4S)-4- α ON20_RS24140 ON20_RS01050 α-D-galactose a tRNA 5-deoxy-α-ribose dIMP ala a peptide fructose-6- phosphate trehalose-phosphatase: otsB -glycine ligase: dUDP -D-mannosyl-(1->6) ON20_RS17835 6 α L-cystathionine 2-oxobutanoate synthase: carB class 1b ribonucleoside- hydroxy-2,3,4,5- beta-ketoacyl- E2 protein] N - methylpropanoyl]dihydrolipoyl- UDP- -D-glucose a 2,3-dihydroxybenzoyl- a ferricytochrome containing a DMKH adenine succinate UTP--glucose- trehalose-phosphatase: otsB reductase α class II fructose- 1-phosphate oleoyl-CoA 2 a palmitoyl-[acp] 1-phosphate phosphate isomerase, ON20_RS02415 type II 3- ACP reductase: - -D-mannosyl-(1->6) [+ 3 isozymes] dihydrolipoyl-L-lysine L-lysine 3-oxododecanoyl-CoA pyruvate 1-phosphate ON20_RS15770 adenylo-succinate subunit alpha: nucleoside-diphosphate diphosphate reductase tetrahydrodipicolinate α a 1,2-diacyl- bisphosphate a 5'-phospho- a 3'-phospho- a modified [aryl-carrier protein] b 3' CCA end semialdehyde transaminase class I: manA dehydroquinate ON20_RS15195 - -D-mannosyl]- 4-oxo-2-pentenal 5 α,α-trehalose kinase: ON20_RS06935 subunit beta: nrdF sn-glycerol [DNA] [DNA] nucleobase (isomerizing) D-mannopyranose uridylyltransferase: ON20_RS18170 dehydratase: aroQ a (3R)-3- 1-phosphatidyl- DHAP aldolase: acetyl-CoA C- GAR carbamoyl adenylosuccinate : glmS ON20_RS21605 asp class 1b dUTP dCDP 1D-myo-inositol 3-phosphate ON20_RS24125 acetyltransferase: 6-phosphate lyase: hydroxydecanoyl- phosphate 3-dehydroshikimate dipicolinate phosphatidate ON20_RS21060 D-glucosamine phosphomannomutase/ UTP--glucose- heptadecane phosphoribosylglycinamide ribonucleoside- dUTP diphosphatase: nucleoside-diphosphate [acp] UDP- trans,octacis a 2'- all-trans- (-)-methyl androst-4-ene- ON20_RS02435 cytidylyltransferase: triose-phosphate 2-oxo acid a D-aminoacyl- a 3-oxosteroid pyridoxamine cyanate 6-phosphate phosphoglucomutase: 1-phosphate biosynthesis formyltransferase: diphosphate cob(II)inamide acetoacetate -decaprenyl deoxyribonucleoside dodecaprenyl 1,4-dihydroxy- acetyl-CoA propanoyl-CoA 3,17-dione ON20_RS16360 kinase: ON20_RS06935 shikimate isomerase: dehydrogenase decanoyl-CoA glucose 4- ATP PRPP [DNA] [tRNA] jasmonate GTP (2S)-2- GTP 5'-phosphate uridylyltransferase: aspartate reductase ON20_RS17235 phosphate 5'-triphosphate diphosphate 2-naphthoate 3-ketosteroid- phosphoglucosamine ON20_RS19860 ON20_RS21745 nucleoside triphosphate dehydrogenase: epimerase 3-ketosteroid- pyridoxamine UDP-α-D-galactofuranose carbamoyltransferase AMP dCTP a CDP- ON20_RS15600 subunit E2: phospholactate α-D-mannose ON20_RS08825 stearate subunit beta: nrdF ON20_RS15870 acyl-CoA GalE: galE bifunctional delta-1- delta-1- 5'-phosphate mutase: ON20_RS21255 biosynthesis pyrophosphohydrolase: fatty acid elongation -- saturated ON20_RS05230 acetoacetate--CoA carboxylesterase/ acetyl-CoA long-chain- FGAR catalytic subunit: a (2E)-dec- diacylglycerol dehydrogenase: decaprenyl-phosphate DNA polymerase diguanylate cyclase/ dehydrogenase: dehydrogenase: oxidase: cyanase: α 1-phosphate dTDP-L-rhamnose UDP-α-D-glucose dCDP ON20_RS28640 cob(I)yrinic acid a,c-diamide 1,4-dihydroxy- D-tyrosyl- -D-glucosamine fatty acid--ACP ON20_RS15785 CMP shikimate 2-enoyl-[acp] D-glyceraldehyde ligase: ON20_RS10360 lipase family acetyltransferase: 2-phospho-L-lactate ON20_RS14425 ON20_RS14425 cynS biosynthesis UDP-α-D-glucose phosphoribosylformylglycinamidine adenylate kinase: ON20_RS10075 adenosyltransferase: cobO phosphoribosyltransferase: III subunit epsilon: 2-naphthoate tRNA(Tyr) phosphodiesterase: ON20_RS18325 1-phosphate ligase MbtM: dUMP phosphorylation 3-phosphate acetoacetate--CoA protein: ON20_RS29895 guanylyltransferase: α synthase: ON20_RS02465 ON20_RS04250 enoyl-ACP an acetoacetyl-[acp] [+ 55 isozymes] cob(I)yrinic acid a,c-diamide ON20_RS00470 ON20_RS27530 polyprenyltransferase: deacylase: ON20_RS04380 3-oxosteroid 1- 3-oxosteroid 1- [+ 4 isozymes] -D-glucopyranose ON20_RS14115 UDP-glucose 4- nucleoside- shikimate kinase: ligase: ON20_RS22435 ON20_RS28445 [+ 8 isozymes] bifunctional UDP-N- N-carbamoyl- thymidylate synthase: reductase FabI: α-D- [+ 9 isozymes] ON20_RS23000 ON20_RS04260 cofC dehydrogenase: dehydrogenase: GDP-α-D- 1-phosphate epimerase GalE: galE ON20_RS02470 ON20_RS02485 diphosphate CMP ON20_RS34495 type I glyoxylate cycle UDP-α-D- adenosyltransferase: diguanylate cyclase: PLP acetylglucosamine a stearoyl-[acp] UDP-α-D-galactose L-aspartate ON20_RS21840 ON20_RS15190 (2E)-dec-2-enoyl-CoA glucopyranose [+ 2 isozymes] ON20_RS01830 ON20_RS01830 ammonium CO glucose-1-phosphate kinase: (d)CMP kinase: glyceraldehyde- galactose ON20_RS05445 trans,octacis- ON20_RS09445 2 diphosphorylase/ mannose ADP dCMP androsta-1,4- a 3-oxo- thymidylyltransferase FGAM ON20_RS09910 shikimate 3- 3-phosphate 1-phosphate decaprenylphospho- 3-oxopentanoyl- (2S)-lactyl-2- c-di-GMP UDP-galactopyranose ON20_RS06935 dTMP hypothetical acetoacetyl-CoA diphosphate 1 glucosamine-1- dihydroorotase: dCMP deaminase: CDP a decanoyl-[acp] succinate acetyl-CoA β [DNA] DMK-12 an uncharged CoA diphospho- diene-3,17-dione D -steroid RfbA: rfbA mutase: glf phosphate dehydrogenase: protein: AMP -D-ribofuranose a D-amino acid (-)-jasmonate phosphate N- dTDP-α-D-glucose phosphoribosylformylglycinamidine pyrC class 1b ON20_RS23955 dTMP kinase: tmk alpha-D-glucose adenosylcobinamide tRNA MeOH 5'-guanosine dCTP 3-phosphoshikimate 1- gap ON20_RS17965 triphosphate 5-phosphate acetyltransferase UDP-Galf cyclo-ligase: ON20_RS02525 ribonucleoside- dTMP kinase: nucleoside- beta-ketoacyl- a 3-oxoacyl-[acp] phosphate-specific dTDP-glucose 4,6- dUMP diphosphate carboxyvinyltransferase: glyoxylate [+ 2 isozymes] GlmU: glmU PRPP biosynthesis octadecanal (S)-dihydroorotate diphosphate ON20_RS19795 ACP synthase II: isocitrate lyase/ phosphoglucomutase: dehydratase: rfbB kinase: aroA N-acetyl-α-D- AIR reductase thymidylate ON20_RS23770 13-DPG phosphoenolpyruvate (S)-3- ON20_RS18770 dTDP-4-dehydro-6- dTDP 5-enolpyruvoyl- phosphatidylserine and malate a 2'- glucosamine D-ribose 5- quinone- subunit alpha: synthase: ON20_RS06935 a 3- hydroxydecanoyl-CoA [+ 2 isozymes] all-trans- a 1-acyl-2- androsta-1,4- (24R,25R)- 2''-O-acetyl- (3R,5S)-3- a [protein]-L- deoxy-α-D-glucopyranose shikimate 3- phosphatidylethanolamine mutase family protein: synthase G: cob(II)alamin a mycofactocinone ethanol 1,4-dihydroxy- 5-(carboxyamino) dependent nucleoside-diphosphate oxododecanoyl- ala a pimeloyl-[acp] deoxyribonucleoside tridecaprenyl arachidonoyl- diene-3,17-dione a tRNA precursor 3α,7α,12α,24- sarcosine repressor LexA ADP-ribose hydroxy-1- methionine 1-phosphate phosphate ON20_RS18170 ON20_RS21840 CTP phosphate beta-ketoacyl- ON20_RS28960 ON20_RS11470 (S)-3- D-glucopyranose ATP [DNA] ribose-phosphate dTDP-4- imidazole dihydroorotate kinase: ON20_RS06935 [acp] biosynthesis I phosphoglycerate 5'-triphosphate diphosphate 2-naphthoate sn-glycerol 3-ketosteroid-9- tetrahydroxy-5β- pyrroline-5- peptide- bifunctional UDP-N- chorismate ACP reductase: isocitrate lyase: hydroxydecanoyl- 6-phosphate transcriptional diphosphokinase: dehydrorhamnose ribonucleotide dehydrogenase: class 1b dTMP beta-ketoacyl- a CDP-diacylglycerol kinase: pgk 3-phosphate CTP alpha-hydroxylase cholestanoyl 3-alpha,7-CoA carboxylatepyrroline-5- methionine acetylglucosamine heptadecane dTTP beta-ketoacyl- CoA repressor LexA: O-acetyl- ON20_RS21370 3,5-epimerase: rfbC mutase: purE ribonucleoside- synthase: ON20_RS15195 ON20_RS23445 NDMA-dependent subunit A: alpha, 12-alpha- (S)-S-oxide ON20_RS13105 dTMP kinase: tmk ACP reductase: ACP synthase II: phosphatidylcholine/ dehydrogenase: cob(I)yrinic acid a,c-diamide 8-amino-7- DNA polymerase 1,4-dihydroxy- ON20_RS16540 ADP-ribose carboxylate diphosphorylase/ PRPP dTDP-4-dehydro- diphosphate ON20_RS15845 alcohol ribonuclease D: trihydroxy-5-beta- glycine oxidase asp PRPP dTMP kinase: ON20_RS15195 phosphatidylserine oxononanoate III subunit epsilon: 2-naphthoate phosphatidate ON20_RS14500 deacetylase: reductase: reductase glucosamine-1- β CAIR orotate ON20_RS23770 a (3R)-3- 3-phospho- ON20_RS01050 adenosyltransferase: dehydrogenase: ON20_RS16300 ThiO: thiO transcriptional -L-rhamnose reductase a (3R)-3- a 2,3,4-saturated synthase: cholest-24-enoyl- ON20_RS23210 MsrA: msrA phosphate N- ON20_RS19795 adenine and adenosine salvage III chorismate hydroxyacyl-[acyl- (R)-glycerate ON20_RS05445 synthase: ON20_RS27530 polyprenyltransferase: cytidylyltransferase: 3-ketosteroid-9- repressor LexA: ON20_RS16115 a protein-L- subunit hydroxydodecanoyl- fatty acyl-[acp] D-threo-isocitrate (S)-malate ON20_RS08080 CoA hydratase: dTDP-4- carrier protein] ON20_RS23585 3-oxodecanoyl-CoA ON20_RS08990 [+ 9 isozymes] ON20_RS23000 ON20_RS17235 alpha-hydroxylase ON20_RS20650 Hyp methionine- acetyltransferase Amine and Polyamine orotate beta: nrdF dTDP [acp] a 3-sn-phosphatidyl- cob(I)yrinic acid a,c-diamide [+ 2 isozymes] (24E)-3α,7α,12ON20_RS01825α- dehydrorhamnose phosphoribosylaminoimidazolesuccinocarboxamide subunit A: cleaved (S)-S-oxide GlmU: glmU phosphoribosyltransferase: L-serine phosphoglyceromutase: acetyl-CoA C- adenosyltransferase: cobO a nucleoside 5'- trihydroxy- methylamine reductase: rfbD Biosynthesis synthase: ON20_RS06495 nucleoside- ON20_RS01930 a tRNA glyoxylate repressor LexA acetate ADP-D-ribose UDP-N-acetyl- ON20_RS24165 adenine ON20_RS23280 8-amino-7- a CDP-1-acyl- monophosphate 5β-cholest- dADP diphosphate phosphatidylserine octanoyltransferase: 9α-hydroxyandrosta- α dTDP-β-L-rhamnose ectoine biosynthesis purine-nucleoside aconitate acyl-carrier protein [DNA] DMKH2-13 2-arachidonoyl- -D-glucosamine decarboxylase: ON20_RS21060 adenosylcobalamin oxononanoate acetaldehyde a mycofactocinol 1,4-diene-3,17-dione 24-enoyl-CoA kinase: hydratase: triphosphate glycerol SAICAR orotidine 5'- phosphorylase: a (2E)-dodec- ON20_RS23590 2-phospho- Aromatic Compound Degradation nucleoside- ON20_RS06935 acnA octanoyl-CoA phosphate ON20_RS04900 2-enoyl-[acp] D-glycerate asp adenylosuccinate diphosphate adenosine an L-1- lyase: kinase: dTTP phosphatidylethanolamine phenylacetate Metabolic Regulator Biosynthesis orotidine-5'- enoyl-ACP acyl-CoA diphenyl ethers aspartate kinase: a trans-2- phosphopyruvate degradation I (aerobic) UDP-N-acetyl-α-D-muramoyl- a methylated a [protein] N-terminal- a 3β-hydroxy- 3''-O-acetyl- ON20_RS02435 phosphate ON20_RS06935 adenosine reductase FabI: a 2,3,4-saturated enoyl-ACP dehydrogenase: degradation di-trans,octa-cis- 3-aci- coenzyme A 1,4-dihydroxy- (S)-2- oxaloacetate roseoflavin ON20_RS01150 hydratase: cis-aconitate oxaloacetate γ 2-oxoglutarate nucleobase GGPP asp O-ureido-L- L-homocysteine Ins(1)P δ 5 ADP-ribose ON20_RS15190 reductase FabI: enoyl-[acyl- L-alanyl- -D-glutamyl-L- nitropropanoate formyl-L-methionine glu cys -steroid decarboxylase: deaminase: fatty acyl-[acp] ON20_RS10075 undecaprenyl phosphate 2-naphthoate aminobutanoate homoserine mannosylglucosylglycerate L-aspartyl- AICAR carrier protein] ON20_RS04440 coenzyme A phenylacetate lysyl-D-alanyl-D-alanine within DNA inositol steroid Delta- bifunctional 2- bifunctional pyrF dATP ON20_RS04860 ON20_RS15190 [+ 55 isozymes] diphenyl ether biosynthesis I 4-phosphate aconitate monophosphatase: isomerase: O-acetyl- methylcitrate riboflavin bifunctional a dodecanoyl-[acp] phosphoenol nitronate CoA pyrophosphatase: peptide UMP inosine-5'-phosphate biosynthesis I hydratase: (2E)-oct-2-enoyl-CoA biphenyl 2,3- phospho-N- alpha- 1,4-dihydroxy- glutamate-- argininosuccinate cystathionine ON20_RS16380 ON20_RS14495 ADP-ribose synthase/citrate kinase/FAD 3-phospho- aspartate- phosphoribosylaminoimidazolecarboxamide inosine pyruvate phenylacetate-- monooxygenase: ON20_RS29455 deformylase: def UDP-α-D-glucose enoyl-ACP acnA dioxygenase: ketoglutarate- 2-naphthoate synthase: beta-synthase: steroid Delta- synthase: synthetase: (R)-glycerate semialdehyde (d)CMP kinase: CoA ligase: paaF acetylmuramoyl- cysteine ligase: inositol deacetylase: formyltransferase/IMP beta-ketoacyl- reductase FabI: hypothetical dependent ON20_RS28425 CoA pyrophosphatase: polyprenyltransferase: peptide isomerase: ON20_RS22055 ribF dehydrogenase: AIR pyruvate, citrate synthase ON20_RS14000 pentapeptide- ON20_RS22095 ON20_RS09745 ON20_RS21050 monophosphatase: ON20_RS16115 cyclohydrolase: ON20_RS21740 ON20_RS09910 purine-nucleoside ON20_RS15190 protein: dioxygenase AlkB: [+ 3 isozymes] ON20_RS01245 ON20_RS23000 deformylase: (2S,3S)-2- roseoflavin 5-(carboxyamino) ACP synthase II: 2: ON20_RS02880 (1S,2S)-3- transferase: [+ 2 isozymes] ON20_RS06875 glucosyl-3- ON20_RS01155 UMP kinase: phosphorylase: water dikinase: ON20_RS23680 ON20_RS09160 methylcitrate ON20_RS23770 acetyl-CoA ON20_RS17965 phenylacetyl-CoA phenoxycyclohexa- ON20_RS15795 δ 5 5'-phosphate phosphoglycerate FAICAR imidazole ribonucleotide ON20_RS07020 [+ 2 isozymes] ON20_RS08745 myo-inositol a 3-oxo- -steroid L-aspartate 4- ON20_RS17245 ON20_RS04900 laurate pyruvate [+ 2 isozymes] [unspecified synthase: ON20_RS05115 3,5-diene-1,2-diol canavaninosuccinate acetate ADP-D-ribose synthase: semialdehyde phosphoenolpyruvate kinase: pyk citrate phenylacetate- 3-oxopropanoate nitrite degradation 3',5'-ADP 4'-phosphopantetheine demethylmenaquinol-4 γ-L-glutamyl-(S)- L-cystathionine bifunctional UDP N5-CAIR (S)-3- undecaprenyl-diphospho-N- a nucleobase an N-terminal L- ON20_RS20415 hypoxanthine a 3-oxotetradecanoyl- acyl-CoA synthase: CoA oxygenase/ UMP formaldehyde succinate products] formate 2-aminobutanoate diaminobutyrate- phosphoribosylaminoimidazolecarboxamide hydroxyoctanoyl-CoA 4-sulfocatechol acetylmuramoyl-L-alanyl-γ-D- within DNA methionyl-[protein] nucleoside- [acp] synthetase: cis-vaccenate ON20_RS14865 reductase: 2-O-(α-D- -2-oxoglutarate formyltransferase/IMP 5-(carboxyamino)imidazole 3-hydroxyacyl-CoA degradation glutamyl-L-lysyl- D-alanyl-D-alanine glucosylglycerate diphosphate beta-ketoacyl- ON20_RS05895 biosynthesis ON20_RS32300 diphenyl glucopyranosyl) transaminase: ectB cyclohydrolase: ON20_RS21740 ribonucleotide mutase: purE hypoxanthine dehydrogenase: biosynthesis I kinase: ACP reductase: [+ 11 isozymes] long-chain fatty ON20_RS32305 ether 2,3-diol 4-sulfocatechol -3-phospho- phosphoribosyltransferase: hpt pyruvate ON20_RS01050 L-2,4- ON20_RS06935 ON20_RS15195 acid activation paaI paaJ biphenyl ether- protocatechuate UDP-N-acetyl-α-D- a 2-oxo (1S,2R)-1- an (S)-2- all-trans- a (2E,4Z)- a protein-L- D-glycerate 3-phospho- gln CAIR lauroyl-CoA a palmitoleoyl-[acp] di-trans,octa-cis- wound RNA N-ethylglycine GDP-α-D-glucose diaminobutanoate IMP a (3R)-3- beta-ketoacyl- muramoyl-L-alanyl-γ-D- [DNA] C-(indol-3- a PII protein a RNA-DNA hybrid Ins(2)P methionine- (R)-glycerate UTP a long-chain 3-oxooctanoyl-CoA ON20_RS32320 2,3-diol 1,2- 3,4-dioxygenase: undecaprenyl phosphate carboxylate ser halocarboxylate retinyl palmitate XTP dienoyl-CoA glutamyl-L-lysyl-D-alanine yl)glycerol UTP RNA helicase: NADPH- (R)-S-oxide diaminobutyrate phosphoribosylaminoimidazolesuccinocarboxamide IMP hydroxytetradecanoyl- ACP synthase II: fatty acid 2-(1,2-epoxy-1,2- dioxygenase: ON20_RS14165 inositol peptide- [acp] an (11Z)-3-ON20_RS23770 long-chain fatty acetyl-CoA C- 3-sulfomuconate 3-phosphate non-canonical purine ON20_RS13720 dependent 2,4- glucosyl-3- acetyltransferase: CTP synthase: synthase: ON20_RS06495 dihydrophenyl) ON20_RS14000 HAD family ribonuclease HI: monophosphatase: glycine methionine α oxooctadec- acid--CoA ligase: TCA cycle TCA cycle IV (2-oxoglutarate decarboxylase) acetyltransferase: 2-oxoacid:ferredoxin exodeoxyribonuclease carboxylesterase/ NTP pyrophosphatase: dienoyl-CoA 2-[2-O-( -D- phosphoglycerate ectA superpathway of guanosine acetyl-CoA (2Z,4E)-2- phospho-N- [protein-PII] ON20_RS16380 ATP-dependent IMP ON20_RS09875 xanthine and oxidoreductase III: xth tryptophan hydrolase: lipase family ON20_RS25270 ON20_RS05625 oxidase (R)-S-oxide mannopyranosyl) SAICAR 11-enoyl-[acp] ON20_RS10490 ON20_RS21060 1,2- hydroxy-6-oxo- acetylmuramoyl- uridylyltransferase: RNA helicase reductase: synthase: (2S)-4-acetamido- dehydrogenase: nucleotides de novo biosynthesis I xanthosine salvage subunit beta: ON20_RS10685 protein: inositol ThiO: thiO reductase α beta-ketoacyl- [+ 11 isozymes] (S)-malate exodeoxyribonuclease synthase: trpB [+ 2 isozymes] nucleoside triphosphate HrpA: ON20_RS06295 -(1->2)- -D- ON20_RS20415 2-aminobutanoate ON20_RS21125 CTP a long-chain epoxyphenylacetyl- 6-phenoxyhexa- pentapeptide- ON20_RS17365 monophosphatase: MsrB: msrB a (2E)-tetradec- ACP reductase: hexanoyl-CoA ON20_RS15945 III: xth ON20_RS09205 [+ 5 isozymes] ON20_RS21860 pyrophosphohydrolase: a (2E)-2- a [protein]-L- glucopyranosyl]- adenylosuccinate fatty acyl-CoA CoA isomerase: 2,4-dienoate transferase: ON20_RS09160 ON20_RS16525 ectoine 2-enoyl-[acp] stearate biosynthesis ON20_RS15195 4-sulfomuconolactone [+ 2 isozymes] ON20_RS28640 enoyl-CoA 3-phospho- 2-O-(α-D- IMP lyase: ON20_RS02435 xanthosine ON20_RS32295 ON20_RS08745 a nucleoside 5'- an unwound RNA glyoxylate methionine synthase: II (bacteria and plants) a (3R,11Z)-3- acyl-CoA a reduced a 2'- D-glyceraldehyde DNA myo-inositol ethylamine D-glycerate enoyl-ACP + a (2R)-2- a uridylylated XMP glucopyranosyl) ectC purine-nucleoside dehydrogenase: 2-oxepin-2(3H)- an acyl-CoA CO H [DNA] 3-phosphate trp a halide anion monophosphate AICAR hydroxyoctadec- 2 ferredoxin [iron- deoxyribonucleoside PII protein -3-phospho- XMP IMP phosphorylase: reductase FabI: ON20_RS10075 ylideneacetyl-CoA undecaprenyl-diphospho-N hydroxy fatty acid a palmitoyl-[acp] 11-enoyl-[acp] UMP sulfur] cluster 5'-monophosphate all-trans-retinol palmitate D-glycerate ectoine dehydrogenase: ON20_RS04900 ON20_RS15190 2-pyrone-6- -acetylmuramoyl-L-alanyl-γ- bifunctional beta-ketoacyl- fumarate hydratase: [+ 55 isozymes] phenol glutamine- ON20_RS21125 xanthine carboxylate D-glutamyl-L-lysyl- D-alanine 2-[2-O-(α-D- phosphoribosylaminoimidazolecarboxamide ACP synthase II: ON20_RS13940 2-maleylacetate hydrolyzing a myristoyl-[acp] trans-hex-2-enoyl-CoA biphenyl degradation mannopyranosyl) asp formyltransferase/IMP ON20_RS23770 class II fumarate 3-oxo-5,6- GMP synthase: XMP a 3-oxooctadecanoyl- a (2E,11Z)- fumarate oxaloacetate α α 2503 a [TusE sulfur (24E)-3α,7α- -(1->2)- -D- 2-O-( -D- cyclohydrolase: ON20_RS21740 beta-ketoacyl- octadeca-2,11- hydratase: aspA malate synthase hypothetical didehydrosuberyl- adenine an (R)-2- 5-α-androstan- a double 3-oxo-24-ethyl- a (2E,4E)- ON20_RS21110 pyrimidine deoxyribonucleotide [acp] carrier protein]-S a uridine 34 in tRNA 2-methylbutanoate cys O-succinyl-L- an all-trans-retinyl ester aci-nitroethane dihydroxy-5β- an unfolded glucopyranosyl]- glucopyranosyl) adenylosuccinate ACP synthase II: dienoyl-[acp] G: ON20_RS11470 protein: CoA semialdehyde biphenyl in 23S rRNA halocarboxylate 3β,17β-diol stranded DNA cholest-5-ene dienoyl-CoA glutamine- FAICAR phosphorylation homoserine ITP protein D-glycerate -D-glycerate beta-ketoacyl- enoyl-ACP ON20_RS17965 biphenyl 2,3- protocatechuate -sulfanylcysteine cholest-24-enoyl-CoA steroid Delta- DNA gyrase steroid Delta- NADPH- chaperonin GMP synthase: ON20_RS23770 3-oxoadipate 3-alpha,7- hydrolyzing XMP dTMP ACP reductase: fumarate reductase/ dioxygenase: degradation II (ortho- non-canonical purine isomerase: subunit A: isomerase: dependent 2,4- GroEL: groL ON20_RS24065 bifunctional dCMP reductase FabI: citrate synthase [+ 2 isozymes] 23S rRNA acetate- alpha, 12-alpha- GMP synthase: a 3-oxohexadecanoyl- cleavage pathway) HAD family carboxylesterase/ nitronate NTP pyrophosphatase: ON20_RS14495 ON20_RS14495 dienoyl-CoA dTMP kinase: tmk (d)CMP kinase: ON20_RS15195 ON20_RS15190 succinate dehydrogenase 2: ON20_RS02880 cis-3- ON20_RS14000 tRNA 2- cystathionine trihydroxy-5-beta- ON20_RS25565 chaperonin ON20_RS21110 phosphoribosylaminoimidazolecarboxamide [acp] a (3R)-3- (S)-3- 3-oxo-5,6- (adenine(2503)-C(2) -CoA hydrolase: lipase family monooxygenase: ON20_RS05625 Zn 2+ RS14615 Zn 2+ guanylate kinase: adenylo-succinate dTMP kinase: ON20_RS09910 flavoprotein subunit: [+ 2 isozymes] phenylcyclohexa- thiouridine(34) gamma-synthase: cholest-24-enoyl- steroid Delta- type I DNA steroid Delta- reductase: formyltransferase/IMP hydroxyoctadecanoyl- a cis- hydroxyhexanoyl-CoA didehydrosuberyl- protocatechuate )-methyltransferase ligase: acs ON20_RS10685 protein: ON20_RS28425 GroEL: groL ON20_RS15750 ON20_RS19795 dCDP beta-ketoacyl- ON20_RS11800 3,5-diene-1,2-diol synthase MnmA: ON20_RS21040 CoA hydratase: nucleoside triphosphate isomerase: topoisomerase: isomerase: ON20_RS06295 GMP cyclohydrolase: ON20_RS21740 vaccenoyl-[acp] 3-hydroxyhexanoyl- CoA protocatechuate RlmN: [+ 4 isozymes] ON20_RS28445 [+ 5 isozymes] a (2E)-2- a protein adenylosuccinate dTDP ACP reductase: [acp] pyrophosphohydrolase: ON20_RS06875 topA ON20_RS06875 nucleoside- [+ 2 isozymes] CoA 3,4-dioxygenase: ON20_RS17225 ON20_RS17815 (24R,25R)-3α,7ON20_RS01825α,24- lyase: ON20_RS15195 succinate citrate 2-methylbutanoyl- [+ 2 isozymes] ON20_RS28640 17-β-hydroxy-5-α- a negatively 3-oxo-24-ethyl- enoyl-CoA diphosphate ON20_RS14165 trihydroxy-5β- a sugar RS24880 a sugar GDP ON20_RS02435 IMP nucleoside- a (3R)-3- dehydrogenase: 3-carboxy-cis CoA diphosphate androstan-3-one supercoiled DNA cholest-4-ene guanylate kinase: fatty acid biosynthesis aconitate hydratase: acnA AMP succinate a (2R)-2- IMP diphosphate kinase: succinate-semialdehyde glyoxylate ON20_RS01050 ,cis-muconate a 2-thiouridine 34 a [TusE sulfur carrier L-cystathionine a halide anion acetaldehyde nitrite cholestanoyl CoA hydroxyhexadecanoyl- initiation (bacteria trans-2,3- biphenyl-2,3-diol a 2-methyladenine 2503 hydroxy fatty acid ON20_RS15750 kinase: ON20_RS06935 a (2E)-octadec- dehydrogenase 5'-deoxyadenosine in tRNA protein]-L-cysteine all-trans-retinol a fatty acid guanine and guanosine salvage [acp] cis-vaccenate and plants) dehydroadipyl-coA in 23S rRNA met AMP ON20_RS06935 2-enoyl-[acp] (NADP(+)): gabD2 3-oxohexanoyl-CoA + + dCTP 2,3- Na RS28990 Na acetyl-CoA enoyl-CoA GDP dTTP enoyl-ACP succinate-semialdehyde dihydroxybiphenyl acetyl-CoA acetyl-CoA hydratase: (2-carboxy- adenylate kinase: reductase FabI: dehydrogenase (NADP(+) acetyltransferase: 1,2-dioxygenase: class 1b guanosine ON20_RS02970 2,5-dihydro- UDP-N-acetyl- undecaprenyldiphospho- 10 an sn-glycero-3- 2251 (9Z,15Z)-12,13- 2-dehydro- carboxylase: an N - α + guanosine (2R,3S)-2- succinate ON20_RS04250 a (2E)-hexadec- ON20_RS15190 ): ON20_RS12420 ON20_RS29895 ON20_RS14360 α an L-methionyl- an L-rhamnoside NADPH NAD α hydantoin L(or D)-O- 2+ 2+ ribonucleoside- purine-nucleoside 5-oxofuran- -D-glucosamine N-acetylmuramoyl-L- DL-allothreonine phospho-N-(acyl) -D- epoxy-octadeca- 3-deoxy-D- Cu RS09870 Cu adenine and ON20_RS10340 [+ 2 isozymes] [initiator tRNA Met ] formyltetrahydrofolate ATP in 23S rRNA methylisocitrate semialdehyde diphosphate nucleoside- class 1b 2-enoyl-[acp] succinate semialdehyde cis-aconitate [+ 8 isozymes] 2-hydroxy-6-oxo- γ glucopyranose phosphoserine adenosine salvage I phosphorylase: [+ 4 isozymes] (3S)- 2-yl)-acetate alanyl- -D-glutamyl-meso ethanolamine 23S rRNA 9,15-dienoateepoxide hydantoinase/ NAD-dependent gluconate a stearoyl-[acp] 6-phenylhexa- 1-phosphate phosphoserine 2-keto-3- reductase ADP superpathway of pyrimidine diphosphate ribonucleoside- ON20_RS04900 enoyl-ACP malonyl-CoA aconitate hydratase: acnA hydroxyadipyl- -2,6-diaminopimeloyl- Bacterial alpha- (guanosine(2251) oxoprolinase succinate- multifunctional oxoglutarate butanoyl-CoA 2,4-dienoate NAD(P)(+) hydrolase: phosphatase deoxygluconate subunit alpha: nucleobases salvage kinase: diphosphate guanine reductase FabI: CoA D-alanyl-D-alanine methionyl-tRNA serine L-rhamnosidase: glycerophosphodiester -2'-O)- family protein: methylisocitrate semialdehyde 2+ 2+ decarboxylase/oxoglutarate ON20_RS20930 kinase: Cd RS00360 Cd ON20_RS18170 ON20_RS06935 reductase adenosine ON20_RS15190 ACP S- transhydrogenase lyase: prpB SerB: serB class 1b isocitrate lyase/ acyl-CoA (4,5-dihydro- formyltransferase: hydroxymethyltransferase: ON20_RS29830 phosphodiesterase: glucose-1-phosphate methyltransferase ON20_RS10235 dehydrogenase: ON20_RS09260 nucleoside- uracil subunit alpha: purine-nucleoside malonyltransferase: dehydrogenase thiamine undecaprenyldiphospho- (Re/Si-specific): epoxide class 1b ribonucleoside- phosphoenolpyruvate dehydrogenase: 5-oxofuran- ON20_RS15705 ON20_RS20945 ON20_RS00265 adenylyltransferase: RlmB: [+ 4 isozymes] ON20_RS10865 serine diphosphate uracil ON20_RS18170 phosphorylase: hypoxanthine a palmitoyl-[acp] ON20_RS08190 pyrophosphate-binding 2,6-dioxo-6- muramoylpentapeptide beta-N- ON20_RS05175 hydrolase: KDGP ribonucleoside- diphosphate mutase family protein: ON20_RS10075 2-yl)-acetate β glgC ON20_RS01710 [+ 2 isozymes] kinase: phosphoribosyltransferase: phosphoribosyltransferase: hpt stearate subunit/dihydrolipoyllysine- acetylglucosaminyltransferase: -L- a non ON20_RS05180 2-O- (9Z,15Z)-12,13-ON20_RS23890 N-carbamoylglycine GTP ON20_RS04900 3-oxoadipyl-CoA phenylhexa- predicted diphosphate ON20_RS06935 reductase ON20_RS04890 class 1b residue succinyltransferase ON20_RS28960 [+ 55 isozymes] an N-formyl- rhamnopyranose rhamnosylated methylguanosine 2251 pyruvate succinate succinate gln Aminoacyl-tRNA Charging adenine a malonyl-[acp] 3-enoate murG sn-glycerol an N- dihydroxyoctadeca- glutaminyl-tRNA reductase subunit alpha: ribonucleoside- acyl-CoA isocitrate lyase: L-methionyl- a tetrahydrofolate acetaldehyde gly rhamnosyl ABC bifunctional pyr operon subunit: ON20_RS20170 2-oxoglutarate D-threo-isocitrate 3-phosphate acylethanolamine ADP-α-D-glucose in 23S rRNA 9,15-dienoate glycine glycine biosynthesis via transamidation GMP crotonyl-CoA met subunit ON20_RS18170 diphosphate synthetase: [initiator tRNA ] + transporter transcriptional regulator/uracil adenine ketoacyl-ACP ON20_RS23445 lipid II (meso UDP acceptor NADH NADP betaine betaine beta: nrdF reductase ON20_RS05895 3-oxoadipate of glycine class 1b phosphoribosyltransferase phosphoribosyltransferase: palmitate synthase III: hypothetical diaminopimelate containing) glu subunit betaine ribonucleoside- ON20_RS16065 [+ 11 isozymes] ON20_RS23600 protein: succinyl-CoA benzoate PyrR: ON20_RS15790 beta: nrdF guanine and guanosine salvage II diphosphate UMP acyl-CoA [+ 2 isozymes] ON20_RS17965 stearoyl-CoA (2-hydroxyphenyl)methyl 1-hydroxy- 7,8-dihydrofolate an (R)-2- an N 3 -methyladenine a DNA containing (12Z,15Z)-9,10- 5-androstene- chloride RS29575 chloride reductase synthetase: NADP-dependent + pimeloyl-CoA ethanol AMP [+ 2 isozymes] pyruvate NADPH H ala RNA epoxyoctadeca- a protein L-ornithine cys (d)CMP kinase: ON20_RS05895 an acetoacetyl-[acp] 6-oxocyclohex-2-ene-1-carboxylate monoglutamate halocarboxylate in DNA a mismatch 3,17-dione subunit guanosine isocitrate dehydrogenase: (S)-3- 12,15-dienoate steroid Delta- dGDP ON20_RS09910 epoxide NDMA-dependent ATP-dependent beta: nrdF dGDP [+ 11 isozymes] ON20_RS04700 hydroxybutanoyl-CoA ornithine cystathionine an L-glutamyl- UMP kinase: hydrolase: alcohol Clp protease isomerase: Gln pyruvate, phosphate carboxylesterase/ dihydrofolate HAD family DNA-3- G/U mismatch- cyclodeaminase: beta-synthase: fluoride RS14930 fluoride [tRNA ] ON20_RS17245 palmitoyl-CoA (S)-3- 8-amino-7- ribonuclease PH: ON20_RS20930 dehydrogenase: proteolytic subunit: ON20_RS14495 dADP nucleoside- dikinase: ON20_RS14215 lipase family protein: reductase: hydrolase: methyladenine specific DNA ON20_RS21300 ON20_RS21050 GTP hydroxybutanoyl- oxononanoate ON20_RS05620 ON20_RS08080 ON20_RS12645 steroid Delta- Asp-tRNA(Asn) nucleoside- UDP diphosphate guanine pyruvate, phosphate ON20_RS28445 ON20_RS24305 ON20_RS10685 glycosylase I: glycosylase: epoxide CoA synthase: [+ 2 isozymes] [+ 3 isozymes] isomerase: pro lanthionine /Glu-tRNA(Gln) diphosphate nucleoside- kinase: dikinase: ON20_RS29075 [+ 2 isozymes] [+ 3 isozymes] [+ 4 isozymes] ON20_RS20335 ON20_RS14940 hydrolase: Co 2+ Co 2+ nucleoside-diphosphate dehydrogeanse: ON20_RS08990 acetaldehyde ON20_RS06875 RS14755 amidotransferase kinase: diphosphate ON20_RS06935 (12Z,15Z)-9,10-ON20_RS23890 a peptide 2+ 2+ kinase: ON20_RS06935 ON20_RS01050 a nucleoside RNA androst-4-ene- Ni Ni gln subunit GatB: hypoxanthine ON20_RS06935 kinase: β an apurinic site an apyrimidinic uracil diphosphate dihydroxyoctadeca- 3,17-dione UTP phosphoribosyltransferase: hpt fatty acid -oxidation I (generic) + 1-hydroxy-6-oxocyclohex- 5,6,7,8- + an (S)-2- ON20_RS17705 ON20_RS06935 dGTP acetoacetyl-CoA phosphoenolpyruvate diphosphate H salicyl alcohol NADP a halide anion 3-methyladenine 8-amino-7- 12,15-dienoate pyridoxal 5'- AMP 2-ene-1-carboxylate tetrahydrofolate hydroxycarboxylate within DNA coenzyme A site in DNA Asp-tRNA(Asn) CTP synthase: oxononanoate phosphate acetyl-CoA C- predicted /Glu-tRNA(Gln) dGTP dATP ON20_RS09875 GMP Secondary Metabolite Biosynthesis a (3Z)-alk-3-enoyl-CoA ABC efflux synthase: acetyltransferase: ON20_RS16140 amidotransferase: CTP ON20_RS31510 ∆ 3 ∆ 2 thiol transporter thiol ON20_RS17780 -cis- -trans- 34 ON20_RS16155 methylerythritol phosphate pathway II methylerythritol phosphate pathway I a nascent peptidoglycan 34 a thiocarboxylated a [protein]-S- a uridine an (S)-2- (9Z,12Z)-15,16- 2-methoxy- 6-(all-trans- pregn-5-ene- an oxidized [+ 8 isozymes] a uridine an alkylated DNA quercitrin 2+ protoporphyrin IX of a thiol ON20_RS17785 myo-inositol enoyl-CoA gly with (L-alanyl-γ-D-glutamyl- [SAMP] C- a tRNA precursor Mg epoxyoctadeca- 6-(all-trans- decaprenyl)-2- nitroaromatic cys [+ 9 isozymes] in tRNA sulfanyl-L-cysteine in tRNA halocarboxylate 3,20-dione group a 5-phosphooxy- biosynthesis isomerase: terminal glycine nonaprenyl)phenol methoxy-phenol steroid Delta- D-glyceraldehyde D-glyceraldehyde acetyl-CoA meso-2,6-diaminopimeloyl- 9,12-dienoateepoxide 2-polyprenyl-6- 2-polyprenyl-6- compound L-glutamyl- pyruvate pyruvate ON20_RS17965 NAD(P)H cystathionine ammonium 3-phosphate 3-phosphate D-glucopyranose D-alanine) tetrapeptide methoxyphenol methoxyphenol isomerase: predicted Gln DNA-3- Bacterial alpha- hydrolase: [tRNA ] tRNA charging tRNA 2- tRNA 2- HAD family magnesium ON20_RS14495 nitroreductase: beta-synthase: ABC 6-phosphate L,D-transpeptidase: thiouridine(34) hydrolase: ribonuclease Z: methyladenine L-rhamnosidase: chelatase: ON20_RS20930 hydroxylase: hydroxylase: ON20_RS14855 1-deoxy-D- inositol-3- a (2E)-2-enoyl-CoA thiouridine(34) ON20_RS21050 met transporter met 1-deoxy-D- ON20_RS28980 ON20_RS28165 glycosylase: ON20_RS29830 epoxide 2-methoxy-6-ON20_RS14375all all trans-ON20_RS14375 steroid Delta- a reduced Asp-tRNA(Asn) phosphate synthase MnmA: synthase MnmA: ON20_RS10685 ON20_RS11510 lys a tRNA Lys ser ser cys Cys arg Arg gly Gly pro a tRNA Pro xylulose-5- xylulose-5- enoyl-CoA 3-hydroxybutyryl- trans-nonaprenyl- isomerase: nitroaromatic of L- /Glu-tRNA(Gln) a tRNA a tRNA a tRNA a tRNA synthase: a 2,3,4-saturated a 2,3,4-saturated (3R [+ 2 isozymes] ON20_RS17815 [+ 4 isozymes] ON20_RS09810 hydrolase: decaprenyl-2- ser phosphate phosphate long-chain fatty acyl-CoA hydratase: CoA epimerase: ON20_RS17815 1,4-benzoquinol ON20_RS06875 compound methionine fatty acid )-3-hydroxyacyl-CoA β-L- (9Z,12Z)-15,16-ON20_RS23890 methoxy-6-1,4- amidotransferase synthase: dxs synthase: dxs ON20_RS24905 acid--CoA ligase:dehydrogenase: ON20_RS02970 ON20_RS30065 Mg- D-serine D-serine phe a tRNA Phe a nascent peptidoglycan a single-stranded quercetin dihydroxyoctadeca- benzoquinol progesterone subunit GatB: elongator Ins(3)P ON20_RS10490ON20_RS10195 34 a [protein]- a 2-thiouridine 34 an alkylated a DNA containing rhamnopyranose protoporphyrin bifunctional serine-- cysteine-- Trp arginine-- Val glycine-- Ile Tyr proline-- Ala asp His Thr glu Met Leu [+ 2 isozymes] γ a [SAMP] C- a 2-thiouridine an (S)-2- mature tRNA oligoribonucleotide D-ala RS10855 D-ala ON20_RS17705 trp a tRNA val a tRNA ile a tRNA tyr a tRNA a tRNA ala tRNA asp his a tRNA thr a tRNA glu a tRNA Met met initiator tRNA met leu a tRNA with (L-alanyl- -D-glutamyl- D-ala a halide anion an apurinic/ 9,12-dienoate lysylphosphatidylglycerol tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA 1-deoxy-D-xylulose 1-deoxy-D-xylulose [+ 11 isozymes][+ 55 isozymes]a 2,3,4-saturated a 2,3,4-saturated (3S terminal glycine in tRNA L-cysteine in tRNA hydroxycarboxylate nucleobase gly gly inositol meso-2,6-diaminopimeloyl- apyrimidinic site Asp-tRNA(Asn) phenylalanine- asn tRNA Asn gln a tRNA Gln synthetase/lysine-- ON20_RS00340 ON20_RS01705 ON20_RS05340 ON20_RS07620 ON20_RS13530 5-phosphate 5-phosphate fatty acyl CoA )-3-hydroxyacyl-CoA monophosphatase: glycine) tetrapeptide /Glu-tRNA(Gln) -tRNA ligase: tRNA ligase LysX: serine-- cysteine-- tryptophan- arginine-- valine-- glycine-- isoleucine-- tyrosine-- proline-- alanine-- aspartate-- histidine-- threonine-- glutamate-- methionine-- methionine-- leucine-- 1-deoxy-D-xylulose- 1-deoxy-D-xylulose- ON20_RS16380 amidotransferase: ON20_RS09500 ON20_RS00165 tRNA ligase: tRNA ligase: -tRNA tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: 5-phosphate 5-phosphate ON20_RS17780 inositol a [2-oxoglutarate- RNase III mRNA 2-methoxy- a [lipoyl-carrier β ON20_RS09505 ON20_RS27055 ON20_RS14035 ligase: trpS ON20_RS18720 ON20_RS06920 ON20_RS28655 ON20_RS08810 ON20_RS09820 ON20_RS17045 ON20_RS15885 ON20_RS15905 ON20_RS15955 ON20_RS16185 ON20_RS17620 ON20_RS21505 ON20_RS21505 ON20_RS24815 reductoisomerase: reductoisomerase: coenzyme A lysine within DNA containing + (S)-1-pyrroline- -D-glucose [+ 2 isozymes] a sulfurated isobutanoate H O malonyl-CoA H a cytosine in DNA 6 an octanoyl-[acp] processing diphosphate 2 3',5'-ADP sulfite 6-(all-trans- protein]-N -[(R) ON20_RS17785 ON20_RS17210 ON20_RS17210 monophosphatase: SAM dehydrogenase gcv protein H a base with lesion 5-carboxylate 6-phosphate a protein [sulfur carrier] 6 L-glutamate an L-methionyl- ON20_RS09160 a 2,3,4-saturated a 2,3,4-saturated E2 protein] N - substrate DNA cytosine octaprenyl)phenol2-polyprenyl-6- -dihydrolipoyl]- inositol-3- an L-phenylalanyl- an L-asparaginyl- an L-glutaminyl- an L-lysyl- an L-seryl- an L-cysteinyl- an L-tryptophanyl- an L-arginyl- an L-valyl- an L-isoleucyl- an L-tyrosyl- an L-prolyl- an L-alanyl- an L-aspartyl- an L-histidyl- an L-threonyl- an L-glutamyl- an L-methionyl- an L-leucyl- gamma- a glycyl-[tRNA Gly ] [elongator MEP MEP fatty acyl CoA 3-oxoacyl-CoA octanoyl-L-lysine methyltransferase: methoxyphenol L-lysine phosphate proteasome an L-glutaminyl- [tRNA Phe ] [tRNA Asn ] [tRNA Gln ] [tRNA Lys ] [tRNA ser ] [tRNA Cys ] [tRNA Trp ] [tRNA Arg ] [tRNA Val ] [tRNA Ile ] [tRNA Tyr ] [tRNA Pro ] [tRNA Ala ] [tRNA asp ] [tRNA His ] [tRNA Thr ] [tRNA Glu ] [initiator tRNA Met ] [tRNA Leu ] G/U mismatch- type III polyketide dihydrolipoyl Met myo-inositol lipoyl(octanoyl) acetate--CoA inorganic ON20_RS19640 phosphoadenylyl- semialdehyde synthase: [tRNA Gln ] tRNA ] specific DNA synthase: hydroxylase: dehydrogenase: ATPase: arc lipoyl transferase LipB: ligase: acs ribonuclease III: diphosphatase: sulfate reductase: dehydrogenase: ON20_RS24905 2-C-methyl-D- 2-C-methyl-D- ON20_RS27455 DNA (cytosine-5-)- 2-methoxy-6-ON20_RS14375all lpdA synthase: ON20_RS29605 ON20_RS17470 ON20_RS01415 glycosylase: ON20_RS07470 a [lipoyl-carrier pruA an unfolded erythritol 4-phosphate erythritol 4-phosphate methyltransferase: trans-octaprenyl- Ins(3)P lipA ON20_RS14940 protein]-N 6 -[(R protein cytidylyltransferase: cytidylyltransferase: ON20_RS00795 1,4-benzoquinol glu a [glycine-cleavage RNase III a 5-methylcytosine )-lipoyl]-L-lysine ON20_RS01695 ON20_RS01695 isobutanoyl-CoA diphosphate octoketide acetyl-CoA a [2-oxoglutarate complex H protein] AMP H + a DNA containing PAPS 4-(cytidine 5'- 4-(cytidine 5'- 5'-deoxyadenosine an unsulfurated acyl-carrier protein an mRNA fragment processing phosphate a modified in DNA met dehydrogenase N 6 -octanoyl-L-lysine diphospho)-2-C- diphospho)-2-C- [sulfur carrier] product mRNA an apurinic/ nucleobase E2 protein] N 6 Amino Acid Biosynthesis methyl-D-erythritol methyl-D-erythritol apyrimidinic site L-histidine biosynthesis -lipoyl-L-lysine superpathway of branched chain amino acid biosynthesis L-lysine biosynthesis I uracil degradation L-isoleucine superpathway of L-serine L-arginine biosynthesis II (acetyl cycle) ammonia 4-(cytidine 5'- 4-(cytidine 5'- I (reductive) biosynthesis IV and glycine biosynthesis I assimilation cycle III diphospho)- diphospho)- PRPP pyruvate uracil 2-C-methyl-D- 2-C-methyl-D- 5-methoxy-6- dCDP a guanine 527 a [DNA]-3'- a 5'-phospho- UDP-N-acetyl- thr asp propanoate 3-phospho- N-acetylglutamyl-phosphate Alcohol Degradation NaMN coenzyme A an apo [peptidyl- isovalerate glycerophosphoserine coenzyme A carbamoyl long chain bifunctional glutamate N- N-acetyl-gamma-glutamyl- glu erythritol kinase: erythritol kinase: methylbenzimidazole VibB L-ornithine hydroxyl [DNA] cys α-D-muramate a protein ATP acyl-CoA (R)-glycerate ammonium carrier protein] class 1b ribonucleoside- in 16S rRNA polyphosphate ATP acetolactate aspartate kinase: phosphoglycerate ON20_RS21480 ON20_RS21480 phosphate 16S rRNA UDP-N- phosphoribosyltransferase: threonine/serine acetyltransferase/amino- phosphate reductase: diphosphate reductase RNA synthase: ON20_RS01150 synthetase: ethanol glycerol and glycerophosphodiester degradation (guanine(527)-N(7) cysteine acetylmuramate ON20_RS13850 dehydrogenase: acid acetyltransferase ON20_RS09680 2-phospho-4-(cytidine 2-phospho-4-(cytidine ethanol degradation I glycerol degradation V degradosome adenylyl cyclase: proteasome: ON20_RS17670 dehydratase: 5,6-dihydrouracil ON20_RS05895 acetylglutamate kinase: argB degradation II nicotinate-nucleotide-- glycerophosphodiester subunit beta: nrdF ATP-dependent dioxygenase: dehydrogenase: ON20_RS17650 ArgJ: ON20_RS09685 type I glutamate-- 5'-diphospho)-2-C- 5'-diphospho)-2-C- holo-ACP acetate--CoA holo-ACP ornithine )-methyltransferase polyphosphate ON20_RS33195 prcA prcB ATP ON20_RS06430 L-aspartyl-4-phosphate dimethylbenzimidazole phosphodiesterase: DNA ligase: ON20_RS23310 ON20_RS17675 [+ 11 isozymes] 3-phosphooxypyruvate ammonia ligase: glnA methyl-D-erythritol methyl-D-erythritol synthase: ligase: acs synthase: carbamoyltransferase: class 1b ribonucleoside- RsmG: ON20_RS01550 kinase: hydantoinase/ amino-acid N- ethanol glycerol glycerol phosphoribosyltransferase: ON20_RS00265 ON20_RS12030 UDP-N-acetyl-α- [+ 4 isozymes] phosphoribosyltransferase: threonine propanoyl-CoA 2-C-methyl-D- 2-C-methyl-D- ethanol ON20_RS06240 ON20_RS06240 diphosphate ON20_RS25485 aspartate- oxoprolinase acetyltransferase: type I glutamate-- bifunctional cobT argF an N 7 - 3-sulfino-L-alanine D-glucosamine- ON20_RS17570 cyclic-AMP a peptide ON20_RS27735 (S)-2-acetolactate ammonia- phosphoserine erythritol 2,4- erythritol 2,4- bifunctional reductase subunit long chain semialdehyde family protein: 2-oxoacid:ferredoxin ON20_RS16725 ammonia ligase: glnA methylguanine 527 enolpyruvate 1-(5-phospho- lyase IlvA: transaminase: acetaldehyde- acetaldehyde- alpha: ON20_RS18170 polyphosphate ketol-acid ON20_RS10235 oxidoreductase glu N-acetyl-L-glutamate N-acetyl-L-glutamate 5-semialdehyde cyclodiphosphate cyclodiphosphate dihydroxyacetone a holo [peptidyl- isovaleryl-CoA diphosphate sn-glycerol a holo-[VibB aryl- β ON20_RS08945 dehydrogenase: ON20_RS02870 CoA/alcohol CoA/alcohol 5-methoxy-6- 3',5'-ADP ser 3',5'-ADP in 16S rRNA [DNA] -D-ribosyl)-ATP reductoisomerase: synthase: synthase: AMP 3-phosphate CDP ON20_RS01155 [+ 4 isozymes] subunit beta: acetylornithine dehydrogenase: a glycerophosphodiester glycerol nicotinate carrier protein] carrier protein] L-citrulline phosphoribosyl- (2Z)-2-aminobut- O-phospho- gln ON20_RS01700 ON20_RS01700 dehydrogenase: dihydroxyacetone methylbenzimidazole ON20_RS17665 L-arginine biosynthesis I (via L-ornithine) ON20_RS15945 transaminase: ON20_RS09525 2-enoate L-aspartate 4- 3-ureidopropanoate L-methionine biosynthesis III ON20_RS09525 kinase subunit ribotide phosphate ATP (2R)-2,3- L-serine ON20_RS09695 2-C-methyl-D-erythritol- 2-C-methyl-D-erythritol- semialdehyde bifunctional glutamate N- acetaldehyde glycerophosphodiester glycerol acetaldehyde L: dhaL diphosphatase: dihydroxy-3- 2-oxobutanoate phosphoserine glutamate synthase: 2,4-cyclodiphosphate 2,4-cyclodiphosphate acetyltransferase/amino- phosphodiesterase: kinase ON20_RS13855 methylbutanoate 4-hydroxy- glu phosphatase gln ON20_RS00140 gltD acetaldehyde an apo-[LYS2 L- a Chi-site containing a 2,3,4-saturated 3,4-dihydroxyphenylacetyl- a peptide with UDP a guanine 46 pregn-5-ene- acetolactate acid acetyltransferase L-homoserine flavodoxin- flavodoxin- ON20_RS00265 GlpK: glpK acetaldehyde DHAP 5-methoxybenzimidazole NaMN coenzyme A a DNA segment L-threonine 3- (S)-malate histidinol 1-(5-phospho-β- dihydroxy-acid tetrahydrodipicolinate SerB: serB dehydrogenase: 2-aminoadipyl- double stranded RecA 1,2-diacyl-sn- CoA an N-terminal in tRNA 3,20-dione-17-ol his synthase: ArgJ: ON20_RS09685 dependent (E) dependent (E) dehydrogenase CTP class 1b ribonucleoside- D-ribosyl)-AMP dehydratase: 2-iminobutanoate synthase: dapA bifunctional glutamine-hydrolyzing glu ON20_RS09525 carrier-protein] DNA with a blunt end glycerol 3-phosphate Xaa-L-proline tRNA steroid Delta- Hin recombinase: O-phosphate malate histidinol (2S,4S)-4- β ON20_RS17670 homoserine O- -4-hydroxy-3- -4-hydroxy-3- (acetylating): diphosphate reductase L-histidine N(alpha) threonine- ilvD glutamate N- -alanine ser carbamoyl-phosphate N-acetyl-L-ornithine sn-glycerol (guanosine(46)-N7) isomerase: ON20_RS35095 dehydrogenase dehydrogenase: phosphoribosyl- hydroxy-2,3,4,5- ON20_RS17675 acetyltransferase: methylbut-2-enyl- methylbut-2-enyl- acetate ON20_RS01845 nicotinate-nucleotide-- hydroxyphenylacetyl- subunit beta: nrdF -methyltransferase: phosphate acetyltransferase/ synthase: carB 3-phosphate holo-ACP -methyltransferase ON20_RS14495 (quinone): hisD AMP dihydroxy-acid ON20_RS04695 [+ 2 isozymes] phosphatidate CoA thioesterase leucyl [+ 4 isozymes] decarboxylase: tetrahydrodipicolinate amino-acid (S)-2-aceto-2- serine diphosphate diphosphate dimethylbenzimidazole synthase: exodeoxyribonuclease class 1b ribonucleoside- TrmB: a DNA segment egtD ON20_RS17115 cyclohydrolase: dehydratase: ON20_RS15770 cytidylyltransferase: PaaI: paaD aminopeptidase: steroid Delta- dihydrodipicolinate acetyltransferase hydroxybutanoate hydroxymethyltransferase: O-acetyl-L- synthase: synthase: acetate--CoA phosphoribosyltransferase: ON20_RS06240 V: recC recD diphosphate (R)-1-amino-ON20_RS08255 acetyl-CoA 7 ON20_RS24695 isomerase: in reverse oxaloacetate his ON20_RS09170 ON20_RS17685 cobT ON20_RS17235 ON20_RS08440 an N - hercynine 2-propanol O 2-oxobutanoate reductase: ArgJ: 2-aceto-2-hydroxy- ON20_RS20945 carbamoyl phosphate L-ornithine homoserine hydrogen sulfide ON20_RS17200 ON20_RS17200 ligase: acs reductase subunit orientation 1-(5-phospho-β-D-ribosyl)- 3-methyl-2- methylguanine 46 ON20_RS06875 ON20_RS12945 ON20_RS09685 (E)-4-hydroxy-3- (E)-4-hydroxy-3- a holo-[LYS2 L- (3,4- alpha: ON20_RS18170 17-α- -2-phosphate 5-[(5-phosphoribosylamino) L-tryptophan biosynthesis butanoate acetyl-CoA DHAP a double stranded DNA coenzyme A a peptide with in tRNA oxobutanoate acetolactate gly methylbut-2-en- methylbut-2-en- 3',5'-ADP 2-aminoadipyl- a CDP-2,3,4-saturated- dihydroxyphenyl) hydroxyprogesterone methylideneamino]imidazole- 4-hydroxy- amino-acid N- isomeroreductase: 5-methoxybenzimidazole with a RecA protein a proteinogenic dUDP synthase: 1-yl diphosphate 1-yl diphosphate nicotinate carrier-protein] diacylglycerol acetate an N-terminal tetrahydrodipicolinate acetyltransferase: ON20_RS17665 4-hydroxy-3- 4-hydroxy-3- ribotide phosphate loaded 3' overhang amino acid 4-carboxamide 2-isopropylmalate branched chain ON20_RS17670 chorismate L-proline reductase: ON20_RS16725 (R)-2,3-dihydroxy- methylbut-2-enyl methylbut-2-enyl bifunctional 1-(5- synthase: amino acid ON20_RS17675 ornithine ON20_RS16810 anthranilate 3-methylpentanoate L-homocysteine diphosphate diphosphate phosphoribosyl)-5-((5- ON20_RS06980 aminotransferase: (S)-2-aceto-2- N-acetyl-L- carbamoyltransferase: argF (S)-2,3,4,5- synthase reductase: reductase: a single- guanine 37 5-(methylsulfanyl) a (1->4)- phosphoribosylamino) 2-isopropylmalate ON20_RS31120 hydroxybutanoate glutamate dihydroxy-acid 5-hydroxybenzimidazole NaMN coenzyme A an apo-[aryl- methanethiol O-succinyl-L- glycerophosphoglycerol a peptide with a (S)-mandelate protoheme D-glucopyranose cerotoyl-CoA MeOH ON20_RS20850 ON20_RS20850 Phe -2,3-dioxopentyl α-D-glucan methylideneamino)imidazole- tetrahydrodipicolinate component I: dehydratase: methionine 4-hydroxy-3- 4-hydroxy-3- carrier protein] homoserine stranded RNA leader sequence in tRNA synthase: leuA branched-chain ketol-acid L-methionine salvage cycle III mandelate racemase/ tRNA glucose 1- 1-phosphate 1,4-alpha-glucan propionyl-CoA catalase/ 4- carboxamide isomerase/ 2,3,4,5- acetylglutamate ON20_RS09185 ilvD synthase: 5-methyltetrahydropteroyltriglutamate- methylbut-2-enyl IPP methylbut-2-enyl IPP amino acid reductoisomerase: dimethyl sulfide Inorganic Nutrient Metabolism muconate lactonizing (guanosine(37)-N1) dehydrogenase: branching carboxylase peroxidase phosphoribosylanthranilate tetrahydropyridine- kinase: argB ON20_RS17810 - homocysteine S- diphosphate diphosphate selenate reduction urea cycle acireductone (2S)-2- aminotransferase: ON20_RS17665 anthranilate dihydroxy-acid degradation II (oxidation) nicotinate-nucleotide-- holo-ACP cystathionine glycerophosphodiester polyribonucleotide ON20_RS03475 protein GlgB: HPI: katG L-citrulline methyltransferase: ON20_RS12940 reductase: reductase: signal enzyme family protein: -methyltransferase ferrochelatase: synthase: mtnC subunit beta: isomerase PriA: isopropylmalate ON20_RS08460 2,6-dicarboxylate N- dehydratase: met methionine dimethylbenzimidazole phosphodiesterase: nucleotidyltransferase: ON20_RS05530 (R)-2,3-dihydroxy- N-acetylglutamyl- [+ 3 isozymes] isopentenyl- isopentenyl- synthase: gamma-synthase: peptidase ON20_RS27035 TrmD: ON20_RS15185 [+ 3 isozymes] 1,2-dihydroxy-5- ON20_RS08205 [+ 2 isozymes] ON20_RS09155 succinyltransferase: ON20_RS17685 2-oxoglutaramate synthase: ON20_RS20850 ON20_RS20850 dimethyl sulfide phosphoribosyltransferase: ON20_RS00265 ON20_RS16860 a (1,6)-α-D- 3-isopropylmalate 3-methylpentanoate phosphate anthranilate diphosphate diphosphate selenate ON20_RS06240 ON20_RS21040 ON20_RS17335 D-glucono- 2-carboxy- dapD metH arg I: lepB mandelate racemase: an N 1 - (methylsulfanyl) glucosyl-(1,4) formaldehyde phosphoribulosylformimino- dehydratase: phosphoribosyltransferase: trpD (S)-3-methyl-2- argininosuccinate Delta-isomerase: Delta-isomerase: sulfate cobT 1,5-lactone cerotoyl-CoA ON20_RS06070 37 pent-1-en-3-one val dihydroxy-acid N-acetyl- synthase: ON20_RS09745 methylguanine -α-glucan AICAR-phosphate leuD leuC N-succinyl-2-amino- N-(5- oxopentanoate ON20_RS09760 ON20_RS09760 adenylyltransferase: ammonium 2+ glycerol sn-glycerol a nucleoside a single- Phe Fe protoporphyrin IX dehydratase: gamma-glutamyl- methionine met S-adenosyl-L-methionine cycle II 3',5'-ADP a holo-[aryl- succinate (R)-mandelate in tRNA 6-ketopimelate phosphoribosyl) branched chain ON20_RS07460 met stranded RNA 2-isopropylmaleate ilvD phosphate adenosyltransferase: L-arginino-succinate argininosuccinate 5-hydroxybenzimidazole nicotinate carrier protein] 3-phosphate diphosphate a leader sequence a peptide -anthranilate [+ 2 isozymes] glutamine- imidazole glycerol succinyldiaminopimelate reductase: amino acid 2-oxoglutarate dimethyl sulfoxide lyase: argH ribotide phosphate dihydroxy-acid phosphoribosylanthranilate ON20_RS15735 DMAPP DMAPP adenosine 5'- hydrolyzing phosphate 3-isopropylmalate transaminase: dapC ON20_RS09680 aminotransferase: argininosuccinate met dehydratase: isomerase: ON20_RS34170 phosphoselenate carbamoyl- synthase: hisH dehydratase: N-acetyl-L- ON20_RS31120 lyase: argH methionine ON20_RS17685 N-succinyl-L,L-2,6- phosphate ON20_RS09165 leuD leuC glutamate 5- bifunctional 1-(5- 4-(methylsulfanyl)-2-oxobutanoate SAM adenosyltransferase: L-arginino- sn-glycero-3- adenine 1518 / a guanine 37 4-bromodiphenyl a supercoiled (S)-3-methyl-2- diaminopimelate branched-chain assimilatory L-ornithine ARP coenzyme A AsbD acyl- coenzyme A [EntB aryl- adenosylcobinamide canavaninosuccinate D-glucopyranose acryloyl-CoA ethanol phosphoribosyl)-5-((5- 5-methyltetrahydropteroyltriglutamate- ON20_RS15735 succinate synthase: carB tyr SAM 1519 (2R,3S)-3- semialdehyde amino acid arg carrier protein phosphoethanolamine adenine in 16S rRNA in tRNA GTP ether duplex DNA oxopentanoate succinyl- sulfate reduction III ON20_RS15770 carrier protein] bifunctional glucose 1- ATP-dependent catalase/ D-erythro-1- isopropylmalate acetylornithine phosphoribosylamino) aminotransferase: - homocysteine S- dimethyl sulfone 16S rRNA tRNA biphenyl 2,3- crotonyl-CoA AICAR branched chain diaminopimelate hydrogencarbonate selenite adenosylcobinamide dehydrogenase: helicase: peroxidase (imidazol-4- transaminase: methylideneamino)imidazole- ON20_RS08460 adenosylmethionine methyltransferase: ON20_RS12940 carbamoyl (adenine(1518)-N(6)/ (guanosine(37)-N1) adenylate/guanylate dioxygenase: carboxylase/ 3-isopropylmalate desuccinylase: dimethyl sulfone sulfate glycerophosphodiester ON20_RS31525 yl)-glycerol amino acid ON20_RS09695 4- carboxamide isomerase/ decarboxylase: speD superpathway of L-cysteine [+ 3 isozymes] phosphate 7,8-didemethyl-8-hydroxy- holo-ACP holo-ACP adenine(1519)-N(6))- kinase/ argininosuccinate -methyltransferase cyclase domain- ON20_RS14000 ON20_RS19435 reductase: HPI: katG dehydrogenase: ON20_RS20460 glutamine- sulfate ornithine phosphodiesterase: 3-phosphate aminotransferase: phosphoribosylanthranilate biosynthesis (mammalian) monooxygenase argininosuccinate synthase: synthase: dimethyltransferase adenosylcobinamide- lyase: argH TrmD: containing protein: [+ 3 isozymes] 4-bromo-2,3- [+ 3 isozymes] ccrA [+ 2 isozymes] ON20_RS17645 N-acetyl-L- ile adenosylmethionine adenylyltransferase: carbamoyltransferase: 5-deazariboflavin ON20_RS00265 imidazoleglycerol- ON20_RS31120 hydrolyzing SfnG: sfnG ON20_RS06240 ON20_RS06240 phosphate D-glucono- a single (R)-methylmalonyl- isomerase PriA: L-homocysteine SAM synthase: synthase: fbiC RsmA: 1 ON20_RS17335 ON20_RS20975 dihydrodiol- acetaldehyde (2S)-2-isopropyl- L,L-diaminopimelate carbamoyl- ornithine decarboxylase: speD ON20_RS07460 argF an N - 1,5-lactone stranded DNA CoA phosphate branched-chain ON20_RS09155 ON20_RS09745 ON20_RS21490 guanylyltransferase: 37 diphenyl ether met methanesulfinate selenodiglutathione N 6 -dimethyladenine 1518 methylguanine [+ 3 isozymes] dehydratase HisB: 3-oxosuccinate phosphate [+ 2 isozymes] L-citrulline ON20_RS08485 amino acid 1-(2- sn-glycerol 6 1519 fumarate cyclic-GMP diaminopimelate synthase: carB 1,2-dihydroxy-5- dAdoMet APS 5-amino-5-(4-hydroxybenzyl)-6- 3',5'-ADP a holo-[AsbD acyl- 3',5'-ADP a holo-[EntB aryl- ethanolamine /N -dimethyladenine L-canavanine in tRNA ON20_RS09130 aminotransferase: carboxyphenylamino) methionine 5'-deoxyadenosine 2-iminoacetate 3-phosphate adenosyl-cobinamide 3-(imidazol-4- epimerase: ON20_RS15770 (methylsulfanyl)pent-1-en-3-one (D-ribitylimino)-5,6-dihydrouracil met carrier protein] carrier protein] in 16S rRNA ON20_RS08460 -1-deoxy-D-ribulose adenosyltransferase: phosphoadenylyl- phosphate yl)-2-oxopropyl ON20_RS21305 L-proline sulfate activation carbamoyl 5-phosphate putrescine ON20_RS15735 sulfate reductase: phosphate 4-methyl-2- diaminopimelate L-ornithine indole-3-glycerol biosynthesis I for sulfonation ile phosphate adenosylhomocysteinase: methanesulfonate glutathioselenol ON20_RS07470 oxopentanoate epimerase: (from L-glutamate) acireductone spermidine histidinol- phosphate SAM ON20_RS19800 a 1-(1-alkenyl) 1402 an [amino group carrier dTDP-4-amino- a [protein]-L- synthase: mtnC a ribonucleoside + a cytidine (3Z)-hex- phosphate branched chain ON20_RS16600 synthase TrpC: synthase: speD cyanate degradation sulfate seleno-L- coenzyme A [EntF L-seryl- a single NADP FMNH γ a folate crotonyl-CoA sulfite meso-diaminopimelate UDP-N-acetyl-α-D-muramoyl- -sn-glycero-3- 2 protein]-C-terminal- - 4,6-dideoxy- proline (ω = 180) ser ornithine glu sulfate homocysteine triphosphate in 16S rRNA 3-en-1-ol transaminase: amino acid ON20_RS09195 spermidine SAH methanesulfonate carrier protein] phosphocholine stranded DNA 16S rRNA (L-glutamyl)-L-glutamate α-D-galactose dihydrofolate peptidylprolyl CHAT domain- crotonyl-CoA carbamoyltransferase: (1S,2R)-1- glutamate L-alanyl-D-glutamate 5-methyltetrahydropteroyltriglutamate- dTDP-4-amino-4,6- hisC aminotransferase: meso-diaminopimelate monooxygenase: assimilatory sulfite CO adenylyltransferase: (cytosine(1402)-N(4) reductase: isomerase: containing carboxylase/ threonine/serine argF 2 carbonic - homocysteine S- acetylglutamate dideoxygalactose ON20_RS31120 C-(indol-3- 5-kinase: 2-hydroxy-5-(methylsulfanyl)- reductase (NADPH) ON20_RS07460 flavin reductase: dehydratase: histidinol- superpathway of L- sfnG hydrogen selenide anhydrase: methyltransferase: ON20_RS12940 holo-ACP )-methyltransferase kinase: argB transaminase: ON20_RS26480 ON20_RS15960 protein: reductase: L-homoserine yl)glycerol ON20_RS06960 S-methyl-5'-thioadenosine : ON20_RS07475 [+ 2 isozymes] UDP-N-acetylmuramoyl- lysoplasmalogenase: DNA primase: ON20_RS30125 branched-chain diaminopimelate γ-L-glutamyl 3-oxopent-1-enyl 1-phosphate synthase: RsmH: [+ 3 isozymes] [+ 4 isozymes] ON20_RS05865 ccrA ON20_RS06430 phosphate biosynthesis 3-phosphate S-methyl-5'- SAH asparagine biosynthesis ON20_RS16200 L-alanyl-D-glutamate-- 5-methyltetrahydropteroyltriglutamate- ON20_RS07695 an [amino group carrier dTDP-4-dehydro-ON20_RS09770 decarboxylase: lysA 5-phosphate APS ON20_RS06240 ON20_RS24155 flavin reductase: ON20_RS08720 a [protein]-L- (3Z)-hex-3- (2S)- transaminase: amino acid asp L-citrulline thioadenosine formaldehyde sulfite hydrogen sulfide [+ 2 isozymes] 2, 6-diaminopimelate - homocysteine S- 4 protein]-C-terminal- α a 7,8-dihydrofolate pyruvate tryptophan L-cysteine ON20_RS28490 an N - 6-deoxy- -D- proline (ω = 0) en-1-yl acetate ethylmalonyl-CoA ON20_RS09125 aminotransferase: glutamate-5- acireductone phosphorylase: asp ligase: ON20_RS08735 methyltransferase: ON20_RS23435 1402 γ-(5-phospho-L- asp synthase: trpB adenosylhomocysteinase: biosynthesis I adenylyl-sulfate a holo-[EntF methylcytidine glucopyranose ON20_RS08460 lys semialdehyde synthase: mtnC ON20_RS04350 sn-glycero-3- ssDNA/pppN(pN) glutamyl)-L-glutamate L-histidinol ON20_RS09205 ON20_RS19800 glyphosate carbamate hydrogencarbonate kinase: cysC SeMet 3',5'-ADP in 16S rRNA aspartate kinase: argininosuccinate L-tyrosine dehydrogenase: cyanase: L-seryl-carrier a fatty aldehyde hybrid phosphate degradation II UDP-N-acetyl-α-D-muramoyl-L-alanyl- phosphocholine n -1 + ON20_RS01150 synthase: biosynthesis I ser ser cynS protein] FMN NADPH H leu indole ON20_RS07260 asparagine asparagine PAPS γ histidinol- L-homocysteine ser -D-glutamyl-meso-2,6-diaminopimelate L-aspartyl- ON20_RS09745 synthase synthase phosphate acquisition phosphatase: 4-phosphate chorismate L-glutamate-5- glyphosate semialdehyde 5-(methylsulfanyl)-2,3- (glutamine- (glutamine- hisN chorismate tryptophan bifunctional S-methyl- 5-MTR-1-P CO cyanate UDP-N-acetyl- decaprenyl-diphospho-N- an [amino group carrier 966 34 glycine biosynthesis II L-arginino- a phosphate 2 a single 37 an N-arachidonoyl-1-acyl-2- a guanine a cytidine (S)-2- 5 a supercoiled a phosphate dioxopentyl 1-phosphate hydrolyzing) hydrolyzing) O-acetyl-L-serine an adenosine fumarate FMN NADH + a 3-oxo-δ -steroid aspartate- mutase: synthase: trpB 5-thioribose-1- cystathionine glycine α-D-glucosamine acetylmuramoyl-pentapeptide DMAPP asp H protein]-C-terminal-γ- gly succinate bifunctional S-methyl- : asnB : asnB monoester stranded DNA in tRNA lysophosphatidylethanolamine in 16S rRNA in tRNA hydroxyglutarate duplex DNA monoester histidinol semialdehyde a [glycine-cleavage ON20_RS21780 ON20_RS09205 phosphate isomerase/ beta-synthase: bifunctional (L-ornithyl)-L-glutamate 16S rRNA tRNA (cytidine(34) L-2- steroid Delta- ATP-dependent L-threonine 5-thioribose-1- bifunctional o- oxidase alkaline 6 argininosuccinate acetylornithine glycine dehydrogenase: complex H protein] N - prephenate methylthioribulose 1- ON20_RS21050 asparagine asparagine ThiO: thiO RNase H/acid undecaprenyldiphospho- (guanine(966)-N(2) -2'-O)- hydroxyglutarate isomerase: DNA helicase histidinol biosynthesis glycine cleavage lyase: argH phosphate isomerase/ acetylhomoserine/ exodeoxyribonuclease flavin reductase: transaminase: phosphatase: oxidase ON20_RS01155 glycine cleavageaminomethyldihydrolipoyl- (S)-1-pyrroline- phosphate dehydratase: synthase synthase phosphatase: muramoylpentapeptide beta-N- tRNA (adenosine(37)-N6) lysophospholipase: L-aspartate )-methyltransferase methyltransferase: oxidase: ON20_RS14495 RecQ: dehydrogenase: prephenate methylthioribulose 1- o-acetylserine VII: ON20_RS20860 ON20_RS18290 system protein L-lysine system protein trp 5-carboxylate ON20_RS28685 (glutamine- (glutamine- ON20_RS08275 -dimethylallyltransferase ON20_RS20095 oxidase: ON20_RS30125 ON20_RS09695 RsmD: rsmD ON20_RS04685 ON20_RS25260 ON20_RS28035 ThiO: thiO hisD L-aspartate 4- L-glutamate phosphate dehydratase: L-alanine sulfhydrylase: (aminomethyl) acetylglucosaminyltransferase: an [amino group carrier an N 2 - a 2'-O- [+ 2 isozymes] L-homoserine GcvH: gcvH GcvH: gcvH arg dehydrogenase: L-cystathionine hydrolyzing) hydrolyzing) glyoxylate ON20_RS20865 ON20_RS09080 flavin reductase: a 3-oxo- a single semialdehyde pyrroline-5- acid phosphatase: murG MiaA: ON20_RS16610 γ 966 34 2-oxoglutarate an alcohol glyoxylate biosynthesis III ON20_RS28685 biosynthesis III ON20_RS30675 phosphonate protein]-C-terminal- -(L- methylguanine methylcytidine ∆ 4 homoserine [+ 2 isozymes] ON20_RS00805 : asnB : asnB ON20_RS08905 ON20_RS28490 -steroid stranded DNA histidinal homoserine gly [+ 2 isozymes] 3-(4- carboxylate sn-glycero-3-phospho- glutamate 5-semialdehyde- in 16S rRNA in tRNA kinase: γ cysteine reductase: cystathionine -lyase: phosphate a ribonucleoside a single-stranded 6 37 a fatty acid ON20_RS05360 dehydrogenase: hydroxyphenyl) 2-oxoglutarate 5-(methylsulfanyl)-ribulose 1-phosphate cys decaprenyl-pyrophosphoryl- UDP N -dimethylallyladenosine N-(arachidonoyl) 2-iminosuccinate succinate 2-yl)-L-glutamate histidinol O-phospho- ON20_RS23210 ON20_RS21050 synthase: cysM C1 Compound Utilization and Assimilation oligodeoxyribonucleotide glutamate synthase: (N-acetylglucosamine)-N- 5'-monophosphate in tRNA ethanolamine + dehydrogenase: ON20_RS05350 pyruvate cysteine asn asn FMNH NAD L-homoserine a [glycine-cleavage 2 a [glycine-cleavage ON20_RS00140 gltD desulfurase: cys acetylmuramyl-(pentapeptide) hisD complex H protein] N 6 6 pro threonine L-homoserine complex H protein] N alanine NADP-specific ON20_RS15480 cys formaldehyde oxidation formaldehyde oxidation -[(R)-lipoyl]-L-lysine formaldehyde synthase: -dihydrolipoyl-L-lysine racemization glutamate VII (THF pathway) II (glutathione-dependent) his cysteine oxidation III a [glycine-cleavage a [mycoredoxin]- mycothiol- an N-arachidonoyl-2-acyl-1- a [release factor]- 2-methoxy-6-(all-trans a uracil 1498 L-gulono- a glucosylated ON20_RS05355 dehydrogenase: phylloquinone NAD(P)H H + a 1-haloalkane α-amylose tyr desulfurase: formaldehyde (mycothiol-dependent) a sulfurated [sulfur carrier] SAM complex H protein] L-cysteine arsenate conjugate lysophosphatidylethanolamine a type IV prepilin L-glutamine -heptaprenyl)phenol in 16S rRNA D-ala 1,4-lactone glycogenin D-ala ala ON20_RS18300 ON20_RS17820 formaldehyde N 6 -octanoyl-L-lysine peptide chain 2-polyprenyl-6- 16S rRNA SMP-30/ 1,4-alpha-glucan 1,4-alpha-glucan thr formaldehyde alanine racemase: glu ala release factor methoxyphenol (uracil(1498)-N(3))- D-alanine--D- gluconolactonase/ branching branching glycine NAD(P)H-quinone haloalkane alanine ligase: oxidase glycine cleavage ON20_RS21205 a 5,10- mycoredoxin: lysophospholipase: N(5)-glutamine hydroxylase: methyltransferase: LRE family protein: protein GlgB: protein GlgB: S-(hydroxymethyl) formaldehyde lipoyl dehydrogenase: dehalogenase: prepilin peptidase: ON20_RS17555 ON20_RS05530 ON20_RS05530 ThiO: thiO system protein D-ala methylenetetrahydrofolate S-(hydroxymethyl) ON20_RS19385 ON20_RS20095 methyltransferase: ON20_RS14375 3 ON20_RS07505 ON20_RS28320 glutathione oxidation V synthase: lipA ON20_RS04925 ON20_RS26340 ON20_RS15840 2-methoxy-6-all an N - GcvH: gcvH prmC D-alanyl-D-alanine a glycogen amylopectin pyruvate bifunctional 5,10- mycothiol trans-heptaprenyl- methyluracil 1498 L-gulonate glutathione- (bacillithiol-dependent) a [release factor]-N 5 [+ 3 isozymes] methylenetetrahydrofolate S-(hydroxymethyl) a [mycoredoxin] sn-glycero-3-phospho- 1,4-benzoquinol in 16S rRNA dependent formaldehyde a [glycine-cleavage -methyl-L-glutamine dehydrogenase/5,10- mycothiol arsenite mycothiolyl-S-S- NAD(P) + phylloquinol N-(arachidonoyl) a fatty acid a halide anion a primary alcohol formaldehyde 5'-deoxyadenosine complex H protein] N 6 an unsulfurated a cleaved type methenyltetrahydrofolate dehydrogenase: met L-cysteine disulfide ethanolamine a peptide dehydrogenase: -[(R)-lipoyl]-L-lysine [sulfur carrier] IV prepilin cyclohydrolase: ON20_RS12810 S-(hydroxymethyl) ON20_RS20045 ON20_RS11035 bacillithiol glutathione- S-formylmycothiol a 5,10- a [pyruvate dehydrogenase E2 5-amino-4- p-nitrophenyl-α-L- a 3,5,7,9,11,13,15- (3R,6R)-1,3,4,6- a (1->4)- a (1->4)- dependent S-(hydroxymethyl) NAD(P)H a plastoquinone H + (S)-4-hydroxymandelate 2-oxoglutarate ectoine 6 PRPP a [protein] Ser/Thr tetrachlorocyclohexa- an arylamine α (S)-NADPHX α (R)-lactate methenyltetrahydrofolate mycothiol a sulfurated [sulfur carrier] SAM protein] N -octanoyl-L-lysine imidazolecarboxyamide rhamnopyranoside hepta-oxo- -D-glucan -D-glucan formaldehyde serine/threonine 1,4-diene 1,4-alpha-glucan 1,4-alpha-glucan bifunctional 5,10- dehydrogenase: mandelate racemase/ hexadecanoyl-[PKS-acp]aldo/keto arylamine N- NAD(P)H-hydrate D-2-hydroxyacid dehydrogenase: haloalkane branching branching muconate lactonizing reductase: protein kinase: dehydratase: dehydrogenase: methylenetetrahydrofolate ON20_RS30625 ON20_RS20045 adenine NAD(P)H-quinone Bacterial alpha- ectoine dehalogenase: acetyltransferase: enzyme family protein: ON20_RS11365 ON20_RS10395 protein GlgB: protein GlgB: dehydrogenase/5,10- formate phosphoribosyltransferase: dehydrogenase: L-rhamnosidase: hydroxylase: ON20_RS26340 ON20_RS28315 ON20_RS21210 ON20_RS16895 S-formylbacillithiol lipoyl synthase: lipA ON20_RS27035 [+ 11 isozymes] ON20_RS05530 ON20_RS05530 methenyltetrahydrofolate S-formylglutathione ON20_RS16065 ON20_RS04925 ON20_RS29830 thpD 9-hydroxy-3,5,7,11,13,15-[+ 7 isozymes] (1S,4R)-2,4,5- an N- a [protein] (L-serine/L- a GlgE-glycogen NADPH starch pyruvate cyclohydrolase: mandelate racemase: hexaoxohexadecanoyl- trichloro-2,5- acetylarylamine threonine) phosphate ON20_RS11035 ON20_RS06070 β-L- [PKS-acp] cyclohexadiene-1-diol 10 a [pyruvate dehydrogenase AICAR NAD(P) + (R)-4-hydroxymandelate rhamnopyranose 4-nitrophenol succinate an N - 5'-deoxyadenosine a plastoquinol 5-hydroxyectoine met E2 protein] N 6 -lipoyl-L-lysine an unsulfurated [sulfur carrier] formyltetrahydrofolate formate formate formyltetrahydrofolate deformylase: purU an N-terminal L- a D-5- UDP-N-acetyl-α-D-glucosamine undecaprenyl-diphospho-N a 1-O-(alk-1-enyl)-sn-glycero- 1-(oleoyl)-sn-glycero-3- 4-fumaryl- an insertion sequence (2R,3S)-3- (2S)- a (1->4)- dioscin rutin alanyl-[S5 protein monosubstituted prephenate α acetamide formate -acetylmuramoyl-L-alanyl-γ- 3-phosphoethanolamine phosphoethanolamine acetoacetate element IS30 isopropylmalate ethylmalonyl-CoA -D-glucan of 30S ribosome] 1,4-alpha-glucan D-glutamyl-L-lysyl- D-alanine ribosomal- transposase: hydantoin 3-isopropylmalate methylmalonyl- prephenate amidase: Asp/Glu/hydantoin branching protein-alanine N- ON20_RS26500 dehydrogenase: CoA dehydratase: ON20_RS16890 Amino Acid Degradation undecaprenyldiphospho- Bacterial alpha- Bacterial alpha- racemase: protein GlgB: lysoplasmalogenase: lysophospholipase: fumarylacetoacetase: acetyltransferase: [+ 22 isozymes] ON20_RS17645 epimerase: mce ON20_RS00305 [+ 4 isozymes] muramoylpentapeptide beta-N- L-rhamnosidase: L-rhamnosidase: ON20_RS16900 ON20_RS05530 ON20_RS24155 ON20_RS20095 fahA rimI an insertion an L-5- 4-methyl-2- (2R)- 3-phenyl-2- acetylglucosaminyltransferase: ON20_RS29830 ON20_RS29830 an N-terminal N-acetyl- acetate L-valine degradation I sequence IS30 with monosubstituted ethylmalonyl-CoA oxopropanoate a glycogen L-leucine degradation I L-threonine degradation I L-citrulline degradation L-lysine murG L-alanyl-[S5 protein oxopentanoate integrated transposon hydantoin degradation VI sn-glycero-3- sn-glycero-3- β-L- of 30S ribosome] ditrans,octacis-undecaprenyldiphospho- a fatty aldehyde 3-O-β-D-glucosyl- oleate acetoacetate fumarate quercetin- UDP L-rhamnopyranose phosphoethanolamine rhamnopyranose val N-acetyl-(N-acetylglucosaminyl)muramoyl- phosphoethanolamine diosgenin 3-glucoside leu thr L-citrulline ornithine lys L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine branched chain threonine/serine branched chain carbamoyltransferase: L-lysine 6- amino acid dehydratase: amino acid argF transaminase: lat aminotransferase: aminotransferase: ON20_RS06430 carbamoyl UDP-N-acetyl-α-D-glucosamine undecaprenyl-diphospho-N-acetylmuramoyl-L- 2-amino-6-[1-hydroxyethyl]- a lyso- D-threo-7,8- a 1-acyl-sn-glycero- a cytidine 1402 a double-stranded an organic allysine ammonium NAD + H O [DNA] reduced riboflavin homogentisate pyrazinamide citrate ON20_RS31120 alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine 2 ON20_RS31120 threonine phosphate 7-methyl-7,8-dihydropterin phospholipid dihydroneopterin 3-phosphocholine in 16S rRNA oligonucleotide molecule 16S rRNA DNA polymerase branched-chain ammonia- glutamine- 2-amino-4-hydroxy-6- flavin reductase: homogentisate cytochrome P450: amidase: aconitate branched-chain undecaprenyldiphospho- (cytidine(1402)-2'-O) oligoribonuclease: III subunit epsilon: amino acid lyase IlvA: hydrolyzing hydroxymethyldihydropteridine nitrite reductase ON20_RS28490 1,2-dioxygenase: ON20_RS34275 ON20_RS11935 hydratase: amino acid muramoylpentapeptide beta-N- lysophospholipase: dihydroneopterin lysophospholipase: -methyltransferase: ON20_RS06325 ON20_RS27530 aminotransferase: aminotransferase: ON20_RS08945 carbamoyl- diphosphokinase: folK large subunit: [+ 2 isozymes] ON20_RS23695 [+ 53 isozymes] [+ 4 isozymes] acnA (2Z)-2-aminobut- 1-piperideine acetylglucosaminyltransferase: [1-(2-amino-7-methyl-4-oxo- ON20_RS20095 aldolase: folB ON20_RS20095 rsmI [+ 8 isozymes] ON20_RS08460 4-methyl-2-ON20_RS08460 phosphate ON20_RS19485 a 2'-O- a nucleoside 5'- 4-maleyl- pyrazine-2- 2-enoate 6-carboxylate murG 7,8-dihydro-3H-pteridin- a nucleoside 5'- riboflavin an alcohol D-threo-isocitrate oxopentanoate synthase: carB methylcytidine 1402 monophosphate acetoacetate carboxylate 3-methyl-2- 6-yl)]ethyl diphosphate monophosphate ON20_RS15770 6-(hydroxymethyl) sn-glycero-3- in 16S rRNA oxobutanoate ditrans,octacis-undecaprenyldiphospho-N- UDP a carboxylate a glycerophosphodiester glycolaldehyde a carboxylate β -7,8-dihydropterin phosphocholine nitrite carbamate acetyl-(N-acetyl- -D-glucosaminyl)muramoyl-L- γ 2-iminobutanoate L-2-aminoadipate alanyl- -D-glutamyl-L-lysyl-D-alanyl-D-alanine isovaleryl-CoA

isobutanoyl-CoA 10 an [amino group carrier protein]- isovaleryl-CoA an N - trans,octacis-decaprenylphospho- a 2-acyl-1-lyso- hesperidin a 2-acyl-sn-glycero- (1S,4R)-2,4,5-trichloro- (2R,3S)-3- phosphoenol C-terminal-γ-(L-glutamate 5- [DNA] DNA with lesion ferroheme o propionitrile pyruvate dehydrogenase: formyltetrahydrofolate phe β-D-arabinofuranose phosphatidylethanolamine 3-phosphocholine 2,5-cyclohexadiene-1-diol isopropylmalate pyruvate CO decaprenylphospho-beta- semialdehyde-2-yl)-L-glutamate HsdR family type excinuclease ON20_RS22420 2-oxobutanoate 2 N-acetyl-gamma- haloalkane 3-isopropylmalate nitrile hydratase pyruvate D-erythro-pentofuranosid- I site-specific ABC subunit UvrA: heme A synthase: pyruvate 3-methylcrotonyl- L-serine degradation glutamyl-phosphate Bacterial alpha- dehalogenase: dehydratase: subunit beta: carboxylase: phenylalanine 4- 2-ulose 2-reductase: lysophospholipase: lysophospholipase: deoxyribonuclease: ON20_RS10595 ON20_RS15520 kinase: pyk methylacrylyl-CoA CoA reductase: L-rhamnosidase: ON20_RS26340 leuD leuC ON20_RS24640 ON20_RS17500 monooxygenase: ON20_RS00570 ON20_RS20095 ON20_RS19155 an [amino group carrierON20_RS09680 protein]- ON20_RS29830 ON20_RS20095 a double stranded (1S,4S)-2,5-dichloro-2,5- [+ 5 isozymes] (2S)-2- methylcrotonoyl- trans,octacis-decaprenylphospho- DNA without ferroheme a propionamide oxaloacetate pyruvate ser ON20_RS04800 γ enoyl-CoA CoA carboxylase: β-D-erythro-pentofuranosid-2-ulose C-terminal- -(5-phospho- DNA with 5'- cyclohexadiene-1,4-diol lesion isopropylmalate hydratase: propanoyl-CoA L-proline degradation threonine/serine L-glutamyl)-L-glutamate β terminal phosphate ON20_RS22410 10 hesperitin-7-O- -L- dehydratase: 4a-hydroxy-N - sn-glycero-3- sn-glycero-3- ON20_RS02970 a carboxylate β-D-glucoside rhamnopyranose a carboxylate acetyl/propionyl/ phosphate ON20_RS06430 formyltetrahydrofolate tyr phosphoethanolamine phosphocholine [+ 2 isozymes] 2-aminoprop- methylcrotonyl- propionyltransferase: pro (S)-3-hydroxy- 2-enoate CoA carboxylase ON20_RS23970 proline isobutanoyl-CoA subunit alpha: dehydrogenase: a [2-oxoglutarate 3-hydroxyisobutyryl- propanoyl UDP-N-acetyl-α-D-muramoyl- 2,5-dichloro-trans a 1-acyl-2-lyso- naringin a monocarboxylic cytidine ON20_RS05055 ON20_RS20515 D-alanyl-D-alanine acetaldehyde uroporphyrinogen-III dehydrogenase E2 protein] oxaloacetate a uridine in tRNA 3-cyanopyridine meso-tartrate (S)-lactate CoA hydrolase: phosphate (S)-1-pyrroline- L-alanyl-γ-D-glutamyl-L-lysine -dienelactone phosphatidylethanolamine acid amide nucleoside 3-methylglutaconyl- aldehyde dehydrogenase uroporphyrinogen-III C- N 6 -dihydrolipoyl-L-lysine tRNA ON20_RS05280 5-carboxylate 2-iminopropanoate phosphoenolpyruvate amidase: nitrile hydratase tartrate lactate 2- deaminase: acetate kinase: carboxymethylenebutenolidase: (NADP(+)): ON20_RS07855 methyltransferase: cobA dihydrolipoyl CoA Bacterial alpha- carboxykinase (GTP) dihydrouridine ON20_RS11935 subunit beta: dehydrogenase: monooxygenase: (S)-3-hydroxy- ON20_RS23965 UDP-N-acetylmuramoyl- ON20_RS00710 dehydrogenase: ON20_RS27995 lysophospholipase: aldehyde dehydrogenase uroporphyrin-III L-rhamnosidase: synthase DusB: [+ 4 isozymes] ON20_RS24640 ON20_RS31085 ON20_RS06075 isobutanoate tripeptide--D-alanyl- lpdA : ON20_RS24675 [+ 3 isozymes] ON20_RS20095 (NADP(+)): ON20_RS31920 methyltransferase: ON20_RS29830 a [2-oxoglutarate phosphoenol ON20_RS02640 2-hydroxy-3- propanoate D- alanine ligase: 2,5-dichloromaleylacetate a 5,6-dihydrouridine a monocarboxylate nicotinamide acetate uridine 3-hydroxyisobutyrate L-glutamate-5- acetate ON20_RS23165 dehydrogenase E2 pyruvate oxosuccinate dehydrogenase: ON20_RS08740 in tRNA HMG-CoA semialdehyde pyruvate precorrin-2 6 sn-glycero-3- β-L- protein] N -lipoyl-L-lysine mmsB a carboxylate prunin L-glutamate phosphoethanolamine rhamnopyranose (S)-methylmalonate- hydroxymethylglutaryl- UDP-N-acetyl-α-D-muramoyl-L-alanyl- gamma- semialdehyde CoA lyase: L-glutamine γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine semialdehyde ON20_RS10725 degradation I dehydrogenase: methylmalonate- [+ 2 isozymes] L-glutamine a mature peptidoglycan (meso 2-chloro-trans a 5-carboxymethylaminomethyluridine 34 α-D-glucopyranose (5R)-5-benzyl- (indole-3-yl) pruA benzaldehyde vernolate oxaloacetate β-lindane 15-cis-phytoene L-tartrate semialdehyde -diaminopimelate containing) Leu an acyl phosphate acetoacetate gln degradation II -dienelactone in tRNA CTP 1-phosphate hydantoin acetonitrile dehydrogenase: tRNA (cytidine(34) aldehyde dehydrogenase epoxide hydrolase: pyridoxal 5'- glu citrate synthase haloalkane Asp/Glu/hydantoin phytoene tartrate nitrile hydratase (S)-3-amino-2- mmsA carboxymethylenebutenolidase: -2'-O)- (NADP(+)): ON20_RS07855 ON20_RS20930 acylphosphatase: methylpropanoate phosphate gln endolytic transglycosylase glucose-1-phosphate 2: ON20_RS02880 dehalogenase: racemase: desaturase: dehydrogenase: subunit beta: ON20_RS00710 methyltransferase: aldehyde dehydrogenase epoxide hydrolase: ON20_RS17430 synthase: glutamate MltG: ON20_RS15875 cytidylyltransferase: [+ 2 isozymes] ON20_RS26340 ON20_RS16900 ON20_RS08665 ON20_RS31085 ON20_RS24640 ON20_RS04685 (NADP(+)): ON20_RS31920 ON20_RS23890 hydrogencarbonate ON20_RS16140 synthase: [+ 4 isozymes] 1,2-dihydroxypropane- 2,3,4,5,6- (5S)-5-benzyl- 9,15,9'-tri-cis 2-hydroxy-3- (indol-3-yl) 2-chloromaleylacetate a 5-carboxymethylaminomethyl- (9Z)-12,13- ON20_RS09340 a carboxylate L-phenylalanine ON20_RS16155 ON20_RS00140 benzoate 1,2,3-tricarboxylate pentachlorocyclohexanol hydantoin -ζ-carotene oxosuccinate acetamide 2'-O-methyluridine 34 in tRNA Leu dihydroxyoctadeca-9-enoate degradation [+ 9 isozymes] L-glutamate gltD a mature peptidoglycan with (L- a mature peptidoglycan strand CDP-α-D-glucose I (aerobic) glu degradation IX (via glu alanyl-γ-D-glutamyl-meso-2,6- (non-reducing terminus) 4-aminobutanoate) diaminopimeloyl-D-alanine) tetrapeptide L-asparagine phe degradation I phenylalanine 4- glu an (S-diacyl-sn- 3-(4- monooxygenase: glutamate an L-1- 2-chloro-cis- a nucleoside 2-hydroxy-2- adenosyl-cob(III) an aromatic glyceryl)-L-cysteinyl- trans-dienelactone an aldehyde hydroxyphenyl) uroporphyrinogen-III ethylphosphate (R)-NADPHX propionamide ON20_RS04800 decarboxylase: L-alanine phosphatidylethanolamine dienelactone triphosphate methylpropanenitrile yrinate a,c-diamide carboxylate asn tyr [apolipoprotein] aldehyde dehydrogenase pyruvate ON20_RS02455 degradation IV nucleoside triphosphate uroporphyrinogen nitrile hydratase acid phosphatase: cobyric acid NAD(P)H-hydrate amidase: carboxylic acid asparaginase: 4-aminobutanoate carboxymethylenebutenolidase: carboxymethylenebutenolidase: (NADP(+)): ON20_RS31920 4-hydroxyphenylpyruvate pyrophosphohydrolase: decarboxylase: subunit beta: ON20_RS08905 synthase: epimerase: ON20_RS11935 reductase: ON20_RS02515 ON20_RS00710 ON20_RS00710 aldehyde dehydrogenase dioxygenase: hppD ala apolipoprotein N- ON20_RS28640 ON20_RS16290 ON20_RS24640 [+ 2 isozymes] ON20_RS17130 ON20_RS23260 [+ 4 isozymes] ON20_RS06415 asp acyltransferase: lnt (NADP(+)): ON20_RS07855 an aromatic 2-chloromaleylacetate 2-maleylacetate a nucleoside 5'- coproporphyrinogen III 2-hydroxyisobutyramide adenosylcobyrate (S)-NADPHX propanoate alanine a carboxylate homogentisate ethanol aldehyde monophosphate dehydrogenase: ald an N-acyl-(S-diacyl- pyruvate a 2-acyl-1-lyso- phosphatidylethanolamine sn-glyceryl)-L- cysteinyl-[lipoprotein] Carboxylate Degradation

3-methyl-2- 5,10-methylene- 5-chloro-trans a double an N-hydroxy- a negatively dCTP propanoyl CoA cis-dienelactone 1-hydroxyneurosporene protoporphyrinogen IX uroporphyrinogen-I 2-hydroxyisobutyramide an aliphatic nitrile n-butyronitrile pyruvate fermentation oxobutanoate tetrahydromethanopterin -dienelactone stranded DNA arylamine supercoiled DNA degradation I pyruvate decarboxylation to acetyl CoA dCTP deaminase: to acetate IV hydroxyneurosporene protoporphyrinogen uroporphyrinogen amidase: arylamine N- nitrile hydratase type I DNA nitrile hydratase carboxymethylenebutenolidase: carboxymethylenebutenolidase: exodeoxyribonuclease ON20_RS24295 3-methyl-2-oxobutanoate methyltransferase: oxidase: decarboxylase: ON20_RS11935 acetyltransferase: subunit beta: topoisomerase: subunit beta: propanoyl-CoA a [pyruvate dehydrogenase pyruvate ON20_RS00710 ON20_RS00710 V: recC recD pyruvate 6 hydroxymethyltransferase: ON20_RS28030 ON20_RS16285 ON20_RS16290 [+ 4 isozymes] ON20_RS28315 ON20_RS24640 topA ON20_RS24640 acyl-CoA E2 protein] N -lipoyl-L-lysine dUTP dehydrogenase panB 2-hydroxy-2- an N- a primary 5-chloromaleylacetate 2-maleylacetate a 5'-phosphooligonucleotide methoxyneurosporene protoporphyrin IX coproporphyrinogen I a relaxed DNA butyramide carboxylase (acetyl-transferring) methylpropanoate acetoxyarylamine aliphatic amide subunit beta: , homodimeric dihydrolipoyl ON20_RS00525 type: aceE dehydrogenase: lpdA 2-dehydropantoate THMPT [+ 3 isozymes] (S)-methylmalonyl- acetyl-CoA formate pyruvate CoA dehydrogenase phosphate (acetyl-transferring) methylmalonyl- a mature peptidoglycan 10 UDP-N-acetyl- CTP (n) 4a-hydroxy-N - 3-phenyl-2- a single 3-amino-4- 3-amino-4- (indol-3-yl) a maltodextrin D-ribofuranose acetyltransferase: E1 component α-D-glucosamine viomycin 4-guanidinobutyramide CoA a [pyruvate dehydrogenase (meso-DAP containing) formyltetrahydrofolate oxopropanoate stranded DNA hydroxybenzaldehyde hydroxybenzoate acetamide ON20_RS23970 a [pyruvate dehydrogenase E2 subunit alpha: pdhA UDP-N-acetylglucosamine malto- dCTP deaminase: epimerase: mce E2 protein] N 6 -S- viomycin arylamine N- amidase: arylamine N- amidase: ribokinase: protein] N 6 -dihydrolipoyl-L-lysine 4a-hydroxytetrahydrobiopterin 1-carboxyvinyltransferase: 4-hydroxyphenylpyruvate deoxyribonuclease ON20_RS24295 (R)-methylmalonyl- endolytic transglycosylase phosphotransferase: acetyltransferase: ON20_RS11935 acetyltransferase: ON20_RS11935 oligosyltrehalose acetyl phosphate acetyldihydrolipoyl-L-lysine dehydratase: ON20_RS20565 murA dioxygenase: hppD IV: ON20_RS19975 ON20_RS07250 ON20_RS14015 ON20_RS28315 ON20_RS28315 synthase: treY CoA MltG: ON20_RS15875 UDP-N-acetyl-α-D- [+ 4 isozymes] [+ 4 isozymes] UTP an N 10 -formyl- (2-hydroxyphenyl) 3-acetylamino-4- 3-acetylamino-4- a maltooligosyl- D-ribofuranose methylmalonyl- acetate kinase: mevalonate degradation [+ 3 isozymes] glucosamine-enolpyruvate a 5'-phosphooligonucleotide O-phosphoviomycin 4-guanidinobutanoate (indol-3-yl)acetate 7,8-dihydrofolate hydroxybenzaldehyde trehalose 5-phosphate CoA mutase: ON20_RS23965 acetate hydroxybenzoate lipoate ON20_RS15135 a mature peptidoglycan GlcNAc-1,6-anhMurNAc- acetyltransferase: (R)-mevalonate (n) acetate acetyl-CoA (meso-DAP containing) L-Ala-γ-D-Glu-DAP-D-Ala succinyl-CoA aceE hydroxymethylglutaryl-CoA superpathway of acetate reductase, degradative: utilization and formation ON20_RS27820

acetate HMG-CoA D-gluconate acetate--CoA degradation ligase: acs acetate kinase: hydroxymethylglutaryl-CoA D-gluconate ON20_RS23965 lyase: ON20_RS10725 gluconokinase: [+ 2 isozymes] ON20_RS12955 acetyl phosphate acetyl-CoA D-gluconate 6-phosphate acetoacetate acetyl-CoA phosphate acetyltransferase: ON20_RS23970 a reduced a reduced plastocyanin an amino an amino an amino plastocyanin acid acid acid an oxidized a branched- a branched- molybdate phosphate a carbohydrate an amino an amino plastocyanin an oxidized an amino chain chain glutamate glutamate glutamate sn-glycerol an inorganic lipid II (meso a polyketide a dipeptide queuosine acid an antibiotic an antibiotic molybdate a nucleotide a nucleotide ammonium D-fructose plastocyanin a carbohydrate a carbohydrate a carbohydrate acid acid amino acid amino acid 3-phosphate anion diaminopimelate containing) predicted predicted predicted predicted predicted predicted ABC ABC ABC ABC cytochrome ABC ABC RS08565 RS28100 RS32865 RS00950 RS17990 RS24885 RS14675 RS15160 transporter of transporter transporter transporter RS29625 RS04465 RS06805 RS03860 RS18015 RS28195 RS28200 RS08280 RS16640 RS23905 RS09660 RS24205 RS24545 RS24855 RS17375 RS31210 RS08755 c oxidase transporter transporter a carbohydrate of an of an of an of molybdate of phosphate amino acid amino acid amino acid a branched- a branched- an inorganic a polyketide D-fructose a dipeptide queuosine a carbohydrate a carbohydrate a carbohydrate an amino an amino an amino an antibiotic an antibiotic molybdate a nucleotide a nucleotide sn-glycerol ammonium chain chain glutamate glutamate glutamate lipid II (meso O a carbohydrate acid acid acid 3-phosphate anion O 2 amino acid amino acid diaminopimelate 2 molybdate phosphate H O an amino an amino an amino containing) H O 2 2 acid acid acid This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.