Scientific UNITED Group International Conference on PharmScience Research & Development March 04-06, 2019

Venue Paris Marriott Charles de Gaulle Airport Hotel 5 Allee du Verger, Zone Hoteliere Roissy en France, 95700 France

Gold Sponsor Publication Partner We are excited to use Whova as our event platform. Attendees please download Whova event app.

The event invitation code is: phaqv Floor Plan

PARIS CHARLES DE GAULLE Gallery 1

Main Meeting Room WiFi Details Network : Marriott_conf Lunch Password : marriottroissy Gallery 2

Loft 3

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Loft 2

Studio Studio Studio Studio Studio Studio Loft 1 1 2 3 Foyer 4 5 6 The Hellenic Society of Medicinal Chemistry (HSMC) supports the publication of the scientific journal ‘Pharmakeftiki’.

The publication of the scientific journal ‘Pharmakeftiki’ started in 1987, within the Hellenic Society of Medicinal Chemistry. Later however, it followed an independent pathway as a quarterly edition on pharmaceutical sciences’ topics, always supported by HSMC and recently also by the Hellenic Pharmaceutical Society (HPS). Since 2012 ‘Pharmakeftiki’ is published both as hard copy and on line as an open access journal .

The journal ‘Pharmakeftiki’ hosts review and research articles addressing all pharmaceutical topics and relevant scientific areas and promotes information on technological achievements and scientific events.

Articles are published after peer-review in both English and Greek language –in the latter case an extended English abstract is required. Articles published in ‘Pharmakeftiki’ are indexed in CHEMICAL ABSTRACTS, EMBASE”, SCOPUS and EBSCO.

The electronic version of ‘Pharmakeftiki’ is accessible in the website of HSMC (www.hsmc.gr/en/pharmakeftiki-journal/) and of HPS www.efe.org.gr

***All registered speakers of the Pharma R&D-2019 will be given an opportunity to publish their full-length manuscript as Conference Proceedings in Pharmakeftiki Journal (Scopus Indexed). Please note that all submitted manuscripts are subjected to an extensive peer review in consultation with the guest editor of the Special issue and editors will make a final decision (accept/reject) on the manuscripts.

Submission Deadline: March 15, 2019 Gold Sponsor Partner with the global leader in tablet compression tooling.

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Natoli Engineering is committed to research and development.

Our commitment to the tablet compression industry means we continuously strive to develop groundbreaking solutions and improvements in our own manufacturing processes and for the entire tableting industry. We are at the vanguard of research and development in the areas of steel types, punch coatings, and tooling design.

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Keynote Session @ Scene 1+2+3

08:00-08:30

Development and Validation of Neutralizing Antibody Assays in Support of Biosimilar Assessment

Arno Kromminga BioAgilytix, Germany

Arno Kromminga studied Biochemistry and is a certified Immunologist and has 20+ years of experience in assay development and clinical diagnostics, is author of multiple publications in peer-reviewed journals and books. He is a board member of the European Immunogenicity Platform (EIP), and member of multiple scientific societies including the European Bioanalysis Forum (EBF), the American Association of Pharmaceutical Scientists (AAPS), German Society of Immunology (DGfI), German Society of Clinical Chemistry and Laboratory Medicine (DGKL). He holds a position as Senior Vice President and Chief Scientific Officer at BioAgilytix, a global bioanalytical CRO.

08:30-09:00

VEGF-A, A Potential Biomarker for Systems Medicine

Sophie Visvikis-Siest UMR INSERM U1122;IGE-PCV/ University of Lorraine, France

Sophie Visvikis Siest is currently working as Research Director in INSERM, France. She is Researcher at the Institute of National Health and Medical Research (INSERM) from 1989 and in 2001 became Director of Research at INSERM. From 1999 to 2009, she had the direction of an INSERM Research team in Nancy “Gene Environment Interactions and Cardiovascular Diseases” and then of a Research Unit in the University of Lorraine. From January 2013, she is director of the Research Unit INSERM UMR U 1122;‘Interactions Géne-Environment en Physiopathologie Cardio-Vasculaire’ (IGE-PCV) at the University of Lorraine. She is the scientific director of the STANISLAS Cohort origin project based on1006 families followed for 15 years. She has published more than 320 papers in international scientific committee journals (index h: 45) and gave more than 70 conferences under invitation. 09:00-09:30

Intracellular Delivery and Oral Bioavailability for Peptides

Thomas Vorherr Novartis, Switzerland

Thomas Vorherr is currently working as Director Peptide Discovery at Novartis (NIBR), Switzerland. He is the Member of the research board, Director Biochemicals at Bachem AG (Bubendorf, Switzerland) from 1997 – 2002. He worked as Managing Director at Amplimmun from 1996-1997. He was the Laboratory Leader in Pharma Research New Technologies in Hoffamann La-Roche from 1992-1996.He was as a Research Assistant at Swiss Federal Institute of Technology (Zurich, Switzerland) He has done his research in Biochemistry on Ca-binding proteins in the group of Prof. Dr. Ernesto Carafoli. He has obtained his PhD in Organic Chemistry at the University of Basel (Basel, Switzerland) 1983 – 1987.

09:30-10:00

Insights to the Biological Transformation of Manufacturing

William G. Whitford GE Healthcare, UT, USA

Bill Whitford is currently working as Strategic Solutions Leader BioProcess GE Healthcare in Logan, UT with over 20 years experience in biotechnology product and process development. He joined the company 13 years ago as a team leader in R&D developing products supporting biomass expansion, protein expression and virus secretion in mammalian and invertebrate cell lines. Products he has commercialized include defined and animal product-free hybridoma media, fed-batch supplements, and aqueous lipid dispersions. An invited lecturer at international conferences, Bill has published over 250 articles, book chapters and patents in a number of fields in the bioproduction arena. He now enjoys such industry activities as serving on the editorial advisory board for BioProcess International. 10:00-10:30

TNF-Related Apoptosis-Inducing Ligand (TRAIL) and PEGylated TRAIL

Kang Choon Lee SungKyunKwan University, South Korea

Kang Choon Lee is Haengdan Distinguished Professor at the SungKyunKwan University (SKKU), Korea, and was director of the Center of Excellence for Future Pharmaceutical Education and Research in the College of Pharmacy at SKKU. He served as a professor and dean at the College of Pharmacy as well as the director of the Institute of Pharmaceutical Science. He has published over 150 papers in peer-reviewed journals and served as an invited speaker at many international conferences. Dr. Lee is an inventor on more than 20 patents related to specific bioconjugation and modification of peptide/protein drugs. He served as president of the Korean-American Pharmaceutical Scientists Association and vice-president of the Pharmaceutical Society of Korea and Korean Society of Pharmaceutical Science and Technology. Dr. Lee is a recipient of the Distinguished Pharmaceutical Scientist Award from the Pharmaceutical Society of Korea in 2002 and honored as a Fellow of the American Association of Pharmaceutical Scientists (AAPS) in 2003. He currently serves on the editorial advisory board of many international scientific journals including Pharmaceutical Research, Pharmaceutical Development and Technology, PharmSciTech, Journal of Drug Delivery and Heliyon. For clinically translating and commercializing of site-specific PEGylated peptide/protein drugs developed by his laboratory, he co-founded D&D Pharmatech, Korea and Theraly Fibrosis, USA.

10:30-10:45 Networking Break @ Foyer

10:45-11:15

Synthesis of a Bone-Targeted Bortezomib with Anti-Myeloma Effect in Mice

Lianping Xing University of Rochester, NY, USA

Lianping Xing is currently working as a Professor at Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, NY, USA. She has obtained PhD in Cell and Molecular Biology from Penn State University in 1994. She has received Young Investigator Award, ASBMRin 1996 and Most Outstanding Abstract Award, ASBMR in 1997, Travel Award, ASBMR and Young Investigator Award, ORS in 2000. She has established NIH funded research programs. She has published 131 Journal articles and 3 books. Her research interests are the involvement of osteoblasts and osteoclasts in inflammatory bone diseases and aging with focus on TNF/Notch signaling pathways and protein ubiquitination and proteasomal degradation, and the role of lymphatic vessels in the pathogenesis of arthritis. She collaborated with Dr. Boeckman from the Department of Chemistry, University of Rochester to generate and test bone-targeted proteasome inhibitor Bortezomib in the treatment of multiple myeloma and bone diseases. 11:15-11:45

Personalized and Precision Medicine (PPM) as National and International Models of Healthcare Services of the Newest Generation: A Green Light Towards the Innovations to Secure Biopharma and Translational Resources

Sergey Suchkov Sechenov University, Russia

Sergey Suchkov was born in the City of Astrakhan, Russia, in a family of dynasty medical doctors. In 1980, graduated from Astrakhan State Medical University and was awarded with MD. In 1985, Suchkov maintained his PhD as a PhD student of the I.M. Sechenov Moscow Medical Academy and Institute of Medical Enzymology. In 2001, Suchkov maintained his Doctor Degree at the National Institute of Immunology, Russia.

From 1989 through 1995, Dr Suchkov was being a Head of the Lab of Clinical Immunology, Helmholtz Eye Research Institute in Moscow. From 1995 through 2004, he is a Chair of the Dept for Clinical Immunology, Moscow Clinical Research Institute (MONIKI). In 1993- 1996, Dr Suchkov was a Secretary-in-Chief of the Editorial Board, Biomedical Science, an international journal published jointly by the USSR Academy of Sciences and the Royal Society of Chemistry, UK.

At present, Dr Sergey Suchkov, MD, PhD, is a Professor, Director, Center for Personalized Medicine, I.M.Sechenov First Moscow State Medical University and Dept of Clinical Immunology, A.I.Evdokimov Moscow State Medical and Dental University; Professor, Chair, Dept for Translational Medicine, Moscow Engineering Physical Institute (MEPhI), Russia; Secretary General, United Cultural Convention (UCC), Cambridge, UK.

11:45-12:15

Seamless Phase IIa/IIb Adaptive Design with the Same Primary Endpoint for Proof of Concept and Dose Finding

Jiacheng Yuan Allergan Inc., CA, USA

Jiacheng Yuan is currently working as a Director of Biostatistics at Allergan Inc. He has worked as an Associate Director of Biostatistics at Bayer HealthCare Pharmaceuticals from 2015-2016. He worked as a Senior Principal Biostatistician at Novartis from 2012-2015. He is active in biostatistics research, and his interest includes adaptive designs, graphical testing procedures, historical control designs, etc. He got his PhD from University of California and Santa Barbara. Notes ______

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______Sponsor Special Talk @ Scene 1+2+3

12:15-13:00 Robert Sedlock Critical Factors - Solid Dosage Formulation & Scale-Up Natoli Scientific, PA, USA

13:00-13:30 Networking Lunch @ Loft

Scientific Session-1 @ Scene 1+2+3 Drug Development & Formulation | Pharmaceutical Chemistry

Chairs: Guofeng You, Rutgers University, NJ, USA Drazen Raucher, University of Mississippi Medical Center, MS, USA

Time Speaker Presentation Title

13:30-13:50 Niklas Axén Drug Delivery Depots Manufactured by Hydration and Isostatic Pressing of Calcium LIDDS AB, Sweden Sulfate

13:50-14:10 Samuel Dorey Study of Gamma-Irradiated Biopharmaceutical Films Used in Single-Use Systems Sartorius Stedim FMT S.A.S, France Applied in the Production of Biopharmaceuticals

14:10-14:30 Gerallt Williams Repurposing CNS Drugs: Opportunities and Challenges via Nasal Drug Delivery Aptar Pharma, France

14:30-14:50 Andre Mischo A Newly Identified Impurity in Polysorbate 80, the Long-Chain Ketone Sandoz GmbH, Austria 12-tricosanone, Forms Visible Particles in a Biopharmaceutical Drug Product

14:50-15:10 Markus Sack Going Green - Plants as Versatile Tools for Drug Discovery, Development and Pro-SPR GmbH, Germany Manufacturing

15:10-15:30 Guofeng You Loops and Layers of Post-translational Modifications of Drug Transporters Rutgers University, NJ, USA

15:30-15:45 Networking Break @ Foyer

15:45-16:05 Drazen Raucher Targeted Delivery of Anticancer Therapeutics Using Elastin-Like Biopolymers University of Mississippi Medical Center, MS, USA

16:05-16:25 Oleg Pisarenko Therapeutic Potential of N-Terminal Fragments of Galanin in Cardiovascular Diseases National Medical Research Center for Cardiology, Russia 16:25-16:45 Helen Osborn Design, Synthesis and Biological Evaluation of Novel Flavone Derivatives University of Reading, UK

16:45-17:05 José Ignacio Bueso Bordils Molecular Topology Applied to Generate Filters to Select Theoretical Antibacterial CEU-Cardenal Herrera University, Spain Compounds

17:05-17:25 Rebeca Ruiz Guevara Solubility Study of Supersaturation and Different Forms of Drug Compounds Using Pion Inc (UK) Limited UK CheqSol Method

17:25-17:45 Sarinj Fattah Synthesis of a Permeation-Enhancer Based Delivery System for Oral Octreotide: University College Dublin, Ireland Intestinal Permeability and Hepatic Disposition Studies

17:45-18:05 Adnan Sabir QbD in Product Life Cycle: Do You Really Know What it Means? Pharma Consultant Services, AL, USA

18:05-18:25 Rahamatullah Shaikh Effect of Co-Milling on the Solid-State Processing of Pharmaceutical Cocrystals University of Limerick, Ireland Notes ______

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______DAY 2 | March 05, 2019 Scientific Session-2 @ Scene 1+2+3 Biopharmaceutics & Therapeutics | Pharmacology | Pharmacognosy

Chairs: Jeffrey Keller,Pennington Biomedical Research Center, LA USA Daniela Monti, University of Pisa, Italy

Time Speaker Presentation Title

08:00-08:20 Andrew Fensome Inhibition of Autoimmune Pathways with Dual Inhibition of JAK1 and TYK2: Discovery Pfizer, MA, USA of PF-06700841

08:20-08:40 Jeffrey Keller The Landscape of Medical Cannabis Research in the United States Pennington Biomedical Research Center, LA, USA

08:40-09:00 Daniela Monti Novel Nanostructured Formulations for Topical Treatment of Actinic Keratosis University of Pisa, Italy

09:00-09:20 Djamel Lebeche Preclinical Validation of SERCA2 Activators as Therapeutics for Diabetes and Beyond The Icahn School of Medicine at Mount Sinai, MA, USA

09:20-09:40 Dong Yun Lee Hexanoyl- and Acetyl-glycol Chitosan Derivatives for Functional Pancreatic Islet Cell Hanyang University, South Korea Spheroid for Treating Type 1 Diabetes

09:40-10:00 Felicia Andrei The Potential of Lavandula angustifolia L. Oil as a Skin Depigmentant Victor Babes University of Medicine and Pharmacy Timisoara, Romania

10:00-10:15 Networking Break @ Foyer

10:15-10:35 Jianzhong Shen Chemokine Receptor CXCR7: A Promising New Target for Atherosclerosis Auburn University, AL, USA

10:35-10:55 Daniella Bajzath Estimation of Serious Adverse Event Occurrence in Clinical Trials with Pneumonia PSI CRO, Germany

10:55-11:15 Josee Guindon CB1, CB2 and Mixed Cannabinoid Agonists in Chemotherapy-Induced Pain and Cancer Texas Tech University Health Sciences Center, TX, USA

11:15-11:35 Monica Marques Telles Ginkgo biloba Extract (GbE) Stimulates the Hypothalamic Serotonergic System and Federal University of Sao Paulo, Brazil Attenuates Obesity in Ovariectomized Rats 11:35-11:55 Lourdes Amable Vega Rasgado Effect of Convulsan Drugs on Nitric Oxide Levels in Astrocites Escuela Nacional de Ciencias Biológicas-IPN, Mexico

11:55-12:15 Amal Qattan Circulating microRNAs: Novel Targets and Specific Therapy in Breast Cancer King Faisal Specialist Hospital & Research Centre, Personalized Medicine Saudi Arabia

12:15-12:35 Martine De Vos Infliximab Trough Levels and Histological Healing in Ulcerative Colitis-A Step Ghent University, Belgium Towards Personalised Biologic Therapy

12:35-12:55 Mehmet Ay Recent Developments in eEF2 Kinase Inhibitors Canakkale Onsekiz Mart University, Turkey

12:55-13:25 Networking Lunch @ Loft

13:25-13:45 Sergey Suchkov Antibodies with Functionality as a New Generation of Translational and Biodesigner’s Sechenov University, Russia Tools Designed to Monitor Demyelination

13:45-14:05 Ni Made Linawati Immunomodulator Potency of Euphorbia Milii and Propolis Combination Tea (EMP) Udayana University, Indonesia through the Secretion of Granzyme B that is Connected with Lung Damage and Hepar Toxicity in Mycobacterium tuberculosis Infected Mice

14:05-14:25 IG Kamasan Arijana Cream of Purple Cabbage Extract Reduce MMP-1 Expression of Male Wistar Rats Back Udayana University, Indonesia Skin Exposed to UV-B Radiation

14:25-14:45 Reiko Yasuda Fabrication of a Novel Culture Dish Adapter with a Small Recess Structure for Flow Kobe University, Japan Control in a Closed Environment

14:45-15:05 Radwan A Hafiz The Risk of Community-Acquired Enteric Infection in Proton Pump Inhibitor Therapy: Saudi Food and Drug Authority, Saudi Arabia Systematic Review and Meta-Analysis

15:05-15:25 Ida Ayu Ika Wahyuniari The Effect of Purple Cabbage Extract on Telomere Shortening in Peripheral Blood

Udayana University, Indonesia Mononuclear Cell Culture Exposed to H2O2

15:25-15:40 Networking Break @ Foyer 15:40-16:00 I Gusti Ayu Dewi Ratnayanti Single Clove Garlic Extract Increase Sirtuin 6 mRNA Expression in PBMC Culture Udayana University, Indonesia

16:00-16:20 Ferah Cömert Önder Significance of eEF2K in Breast Cancer Canakkale Onsekiz Mart University, Turkey

16:20-16:40 Stanley Mukanganyama Isolation and Identification of Phytomedicines from Zimbabwe: Possible Mechanisms University of Zimbabwe, Zimbabwe of Antimicrobial Activity

16:40-17:00 Farah El Mohtadi The Effect of Polysulfide-Conjugation on the Stability and Activity of Lysozyme The University of Manchester, UK

17:00-17:20 Brunel Jean Michel Natural Polyamines: Synthesis and Biological Evaluation INSERM, France

17:20-17:40 Atmani-Kilani Dina C. flammula and F. angustifolia Extracts, Promising Preventive Treatments for University of Bejaia, Algeria Hypercholesterolemia and Dislipidemia

17:40-18:00 Allain Amador Bueno A Dietary Source of Omega 3 Fatty Acids Protects Hypothalamic Fatty Acid University of Worcester, UK Composition but does not Prevent Peripheral Deficiency

18:00-18:20 Hanan Naeim Attia Role of Virgin Coconut Oil in Aluminum-Induced Alzheimer’s Disease in Young and National Research Centre, Egypt Senile Rats

18:20-19:00 Poster Presentations @ Gallery

18:00-19:00 Cocktail Hour @ Gallery Notes ______

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______18:20-19:00 Poster Presentations @ Gallery

PRD P-01 HyeRin Jeong Preparation of Influenza Vaccine Microneedles Using Quick and Standardized Process Gachon University, South Korea for Low Dose Deviation Between Samples

PRD P-02 Ji Seok Kim Coated Microneedles for Skin Immunization of Hepatitis B Vaccine Gachon University, South Korea

PRD P-03 Klemen Rihar Sensitivity of CaCo2 3D Spheroids for Fresh Royal Jelly (F-RY) (M) and HuIFN-αN3 Slovenia

PRD P-04 Kwang-Jin Kim Anti-Osteoclastogenic Activity of Pyrazolopyridine Derivatives Sunchon National University, South Korea

PRD P-05 Yoshitaka Morimatsu Macrophage M2 Differentiation Exposure to Hypobaric Chronic Hypoxia after Kurume University, Japan Administrated to Monocrotaline Hydrochloride in Rats

PRD P-06 Qais Abualassal Synthesis of Spiro Quinazoline Derivative as Potential Drug for the Treatment of Al-Isra University, Jordan Alzheimer’s Disease

PRD P-07 Saleh Mohammed Saeed Alamri Observing Impacts of Uniaxial Pressure on Pharmaceutical Granules Prince Sultan Military Medical Center, Saudi Arabia

PRD P-08 Silvio Naviglio Forskolin Sensitizes Human Acute Myeloid Leukemia Cells to H3K27me2/3 University of Campania “Luigi Vanvitelli”, Italy Demethylases GSKJ4 Inhibitor via Protein Kinase A

PRD P-09 Yongjin Lee Dual Effects of Marine Natural Products on Osteoporosis and Diabetes Sunchon National University, South Korea

PRD P-10 Michael Plioukas How Well Does the Greek Population Know About the Use of Herbal Medicines and University of Nicosia, Cyprus Mainly About St. John’s Wort: The First Quantitative Study in Greece Exploring their Perceptions

PRD P-11 José Ignacio Bueso Bordils DMAP as a Possible Catalyst in the Synthesis of Quinolones CEU-Cardenal Herrera University, Spain

PRD P-12 Tarek A Ahmed Vinpocetine Lyoplant-Tabs: Implementation of New Technique in the Development of King Abdulaziz University, Saudi Arabia Buccal Solid Dosage Form

PRD P-13 Khalid M. El-Say Long Acting Antidiabetic Effect of Glimepiride: Development, Optimization andin vivo King Abdulaziz University, Saudi Arabia Investigation

PRD P-14 Paweł Mierzejewski Comparison of Plasma, Saliva, and Hair Lamotrigine Concentrations Institute of Psychiatry and Neurology, Poland

PRD P-15 Nazanin Rajai Sumatriptan Effects on Morphine-Induced Antinociceptive Tolerance and Physical Tehran University of Medical Sciences, Iran Dependence: The Role of Nitric Oxide DAY 3 | March 06, 2019 Scientific Session-3 @ Scene 1+2+3 Pharma Analysis | Regulatory Affairs | Pharma Education

Chairs: Mirjam Crul, VU medical Center, The Netherlands Maria Cristina C. Doria, University of Santo Tomas, Philippines

Time Speaker Presentation Title

08:00-08:20 Allison Mari Dering Anderson Reflections on 500 Call-in Radio Shows University of Nebraska, NE, USA

08:20-08:40 Syed N Alvi Rapid Determination of Testosterone Level in Human Plasma and Saliva by Ultra- King Faisal Specialist Hospital & Research Centre, Performance Liquid Chromatography-Tandem Mass Spectrometry Saudi Arabia

08:40-09:00 Lijuan Wang Applying Hydrogen Deuterium Exchange Mass Spectrometry to Aid Discovery and Alkermes, MA, USA Development of Protein Therapeutics

09:00-09:20 Gemma Donovan Unlicensed Medicines Use: A UK Guideline Analysis using AGREE II University of Sunderland, UK

09:20-09:40 Sean Bermingham Design Space Characterization and Risk Assessment Through Mechanistic Modelings Process Systems Enterprise Ltd, UK

09:40-10:00 Mirjam Crul The Oncology Pharmacist as Part of the Palliative Treatment Team VU medical Center, The Netherlands

10:00-10:15 Networking Break @ Foyer

10:15-10:35 Sanaa Mekdad Towards Safety of Oral Anti-cancer Agents, the Need to Educate our Pharmacists King Fahad Medical City, Saudi Arabia

10:35-10:55 Nandan Dhir Analytical Method Development of Selected Formulations: Green Approaches Chandigarh University, India

10:55-11:15 Peter Zhang A Case Study in Identifying Targeted Patients Population in Major Depressive Otsuka Pharmaceutical Development & Disorder by Enhanced Enrichment Design Commercialization, Inc., NJ, USA

11:15-11:35 Ylenia Zambito Nanomedicine-Based Strategies to Improve the Resistance of Endothelial Cells to University of Pisa, Italy Oxidative Stress 11:35-11:55 Maria Cristina C. Doria Curriculum Assessment and Redevelopment of the Bachelor of Science in Pharmacy University of Santo Tomas, Philippines Program

11:55-12:15 Gwo-Ping Jong High Exposure to Statins Decrease the Risk of New-Onset Dementia: A Nationwide Chung Shan Medical University Hospital, Taiwan Population-Based Longitudinal Cohort Study

12:15-12:35 Omnia Khairy Mohamed Gadalla Geriatric Education in Schools of Pharmacy: Student’s and Educator’s Perspectives Hamad Medical Cooperation, Qatar in Qatar and Canada

12:35-12:55 Muhammad Akhlaq Colon-Targeted Delivery of Midazolam through Smart Hydrogel Discs Gomal University, Pakistan

12:55-13:15 Ramakrishnan Narasimhan Not Available Enarkay Management Solutions, Canada

13:15 Lunch & Departures @ Loft Notes ______

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______Scientific UNITED Group Let’s meet again at Pharma R&D-2020 March 02-04, 2020 Rome, Italy

# 8105, Rasor Blvd - Suite #112, PLANO, TX 75024, USA Ph: +1-408-426-4832, +1-408-426-4833 Toll Free: +1-844-395-4102; Fax: +1-408-426-4869 Email: [email protected]; [email protected] Web: www.unitedscientificgroup.com/conferences/pharma/