ADAM22 Antibody Cat. No.: 13-385

ADAM22 Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 223-400 IMMUNOGEN: of human ADAM22 (NP_004185.1).

TESTED APPLICATIONS: WB

APPLICATIONS: WB: ,1:1000 - 1:4000

POSITIVE CONTROL: 1) SH-SY5Y

2) Mouse brain

3) Mouse kidney

4) Mouse heart

5) Rat kidney

6) Rat heart

PREDICTED MOLECULAR Observed: 100kDa WEIGHT:

Properties

September 23, 2021 1 https://www.prosci-inc.com/adam22-antibody-13-385.html PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: ADAM22

ADAM 22, EIEE61, MDC2, and domain-containing protein 22, ALTERNATE NAMES: a disintegrin and metalloproteinase domain 22, metalloproteinase-disintegrin ADAM22-3, metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2

GENE ID: 53616

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

This encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom , and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, BACKGROUND: and neurogenesis. Unlike other members of the ADAM , the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.

ANTIBODIES FOR RESEARCH USE ONLY.

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September 23, 2021 2 https://www.prosci-inc.com/adam22-antibody-13-385.html