ADAM22 Antibody Cat. No.: 13-385 ADAM22 Antibody Specifications HOST SPECIES: Rabbit SPECIES REACTIVITY: Human, Mouse, Rat Recombinant fusion protein containing a sequence corresponding to amino acids 223-400 IMMUNOGEN: of human ADAM22 (NP_004185.1). TESTED APPLICATIONS: WB APPLICATIONS: WB: ,1:1000 - 1:4000 POSITIVE CONTROL: 1) SH-SY5Y 2) Mouse brain 3) Mouse kidney 4) Mouse heart 5) Rat kidney 6) Rat heart PREDICTED MOLECULAR Observed: 100kDa WEIGHT: Properties September 23, 2021 1 https://www.prosci-inc.com/adam22-antibody-13-385.html PURIFICATION: Affinity purification CLONALITY: Polyclonal ISOTYPE: IgG CONJUGATE: Unconjugated PHYSICAL STATE: Liquid BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles. Additional Info OFFICIAL SYMBOL: ADAM22 ADAM 22, EIEE61, MDC2, disintegrin and metalloproteinase domain-containing protein 22, ALTERNATE NAMES: a disintegrin and metalloproteinase domain 22, metalloproteinase-disintegrin ADAM22-3, metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2 GENE ID: 53616 USER NOTE: Optimal dilutions for each application to be determined by the researcher. Background and References This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, BACKGROUND: and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants. ANTIBODIES FOR RESEARCH USE ONLY. For additional information, visit ProSci's Terms & Conditions Page. September 23, 2021 2 https://www.prosci-inc.com/adam22-antibody-13-385.html.