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Home , ADAM22, AKAP13, ANKRD25, Ankyrin repeat domain 11, APOBEC3F, Arylformamidase

Table S1: Significant differentially expressed (P -Value<0.05, Fold Change≥1.4), 4 vs. 0 Gy irradiation Genbank Fold Change P -Value Symbol Description Accession Q9F8M7_CARHY (Q9F8M7) DTDP-glucose 4,6-dehydratase (Fragment), partial (9%) 6.70 0.017399678 THC2699065 [THC2719287] 5.53 0.003379195 BC013657 BC013657 Homo sapiens cDNA clone IMAGE:4152983, partial cds. [BC013657] 5.10 0.024641735 THC2750781 Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (HL1). 4.07 0.04353262 DNAH5 [Source:Uniprot/SWISSPROT;Acc:Q8TE73] [ENST00000382416] 3.81 0.002855909 NM_145263 SPATA18 Homo sapiens spermatogenesis associated 18 homolog (rat) (SPATA18), mRNA [NM_145263] AA418814 zw01a02.s1 Soares_NhHMPu_S1 Homo sapiens cDNA clone IMAGE:767978 3', 3.69 0.03203913 AA418814 AA418814 mRNA sequence [AA418814] AL356953 -rich repeat-containing G -coupled 6 {Homo sapiens} (exp=0; 3.63 0.0277936 THC2705989 wgp=1; cg=0), partial (4%) [THC2752981] AA484677 ne64a07.s1 NCI_CGAP_Alv1 Homo sapiens cDNA clone IMAGE:909012, mRNA 3.63 0.027098073 AA484677 AA484677 sequence [AA484677] oe06h09.s1 NCI_CGAP_Ov2 Homo sapiens cDNA clone IMAGE:1385153, mRNA sequence 3.48 0.04468495 AA837799 AA837799 [AA837799] Homo sapiens hypothetical protein LOC340109, mRNA (cDNA clone IMAGE:5578073), partial 3.27 0.031178378 BC039509 LOC643401 cds. [BC039509] Homo sapiens Fas (TNF receptor superfamily, member 6) (FAS), transcript variant 1, mRNA 3.24 0.022156298 NM_000043 FAS [NM_000043] 3.20 0.021043295 A_32_P125056 BF803942 CM2-CI0135-021100-477-g08 CI0135 Homo sapiens cDNA, mRNA sequence 3.04 0.043389246 BF803942 BF803942 [BF803942] 3.03 0.002430239 NM_015920 RPS27L Homo sapiens ribosomal protein S27-like (RPS27L), mRNA [NM_015920] Homo sapiens tumor necrosis factor receptor superfamily, member 10c, decoy without an 2.98 0.021202829 NM_003841 TNFRSF10C intracellular domain (TNFRSF10C), mRNA [NM_003841] 2.97 0.03243901 AB002384 C6orf32 Homo sapiens mRNA for KIAA0386 gene, partial cds. [AB002384] Homo sapiens pleckstrin -like domain, family A, member 3 (PHLDA3), mRNA 2.91 0.025664272 NM_012396 PHLDA3 [NM_012396] CA314451 UI-CF-FN0-afh-a-09-0-UI.s1 UI-CF-FN0 Homo sapiens cDNA clone UI-CF-FN0-afh-a- 2.89 0.002554817 CA314451 CA314451 09-0-UI 3', mRNA sequence [CA314451] BM979607 UI-CF-DU1-adt-k-11-0-UI.s1 UI-CF-DU1 Homo sapiens cDNA clone UI-CF-DU1-adt- 2.86 0.03300029 BM979607 BM979607 k-11-0-UI 3', mRNA sequence [BM979607] 2.84 0.016713949 A_32_P80295 Homo sapiens inositol polyphosphate-5-, 145kDa (INPP5D), transcript variant 1, 2.81 0.04182419 NM_001017915 INPP5D mRNA [NM_001017915] AF264779 sporulation-induced transcript 4-associated protein SAPLa {Homo sapiens} (exp=-1; 2.79 0.03757681 THC2774217 wgp=0; cg=0), partial (3%) [THC2774217] UI-E-CK1-afl-g-13-0-UI.s2 UI-E-CK1 Homo sapiens cDNA clone UI-E-CK1-afl-g-13-0-UI 3', 2.77 0.016352108 BM668321 BM668321 mRNA sequence [BM668321] Homo sapiens heparan sulfate 6-O-sulfotransferase 2 (HS6ST2), transcript variant S, mRNA 2.74 0.005215065 NM_147175 HS6ST2 [NM_147175] Homo sapiens 14 128, mRNA (cDNA clone MGC:15504 2.73 0.004748018 BC007251 C14orf128 IMAGE:2990071), complete cds. [BC007251] 2.70 0.032051645 NM_001002915 IGFL2 Homo sapiens IGF-like family member 2 (IGFL2), mRNA [NM_001002915] 2.69 0.043366723 NM_021151 CROT Homo sapiens carnitine O-octanoyltransferase (CROT), mRNA [NM_021151] BU607658 UI-CF-FN0-aev-j-05-0-UI.s1 UI-CF-FN0 Homo sapiens cDNA clone UI-CF-FN0-aev-j- 2.57 0.017582545 BU607658 BU607658 05-0-UI 3', mRNA sequence [BU607658] 2.57 0.019806402 NM_033285 TP53INP1 Homo sapiens tumor protein inducible nuclear protein 1 (TP53INP1), mRNA [NM_033285] 2.55 0.007933462 AK024092 AK024092 Homo sapiens cDNA FLJ14030 fis, clone HEMBA1004086. [AK024092] AI470277 tj18h01.x1 NCI_CGAP_Gas4 Homo sapiens cDNA clone IMAGE:2141905 3', mRNA 2.55 0.04476883 AI470277 AI470277 sequence [AI470277] Homo sapiens chondroitin beta1,4 N-acetylgalactosaminyltransferase (ChGn), mRNA 2.54 0.048874564 NM_018371 ChGn [NM_018371] 2.54 0.046359118 NM_015460 MYRIP Homo sapiens VIIA and Rab interacting protein (MYRIP), mRNA [NM_015460] 2.53 0.033379793 A_32_P14737 2.48 0.039440684 AW977527 AW977527 EST389636 MAGE resequences, MAGO Homo sapiens cDNA, mRNA sequence [AW977527] xr77d10.x2 NCI_CGAP_Ov26 Homo sapiens cDNA clone IMAGE:2766163 3', mRNA sequence 2.46 0.036104385 BE138567 BE138567 [BE138567] 2.45 0.04575181 AB007457 TP53AP1 Homo sapiens mRNA for P53TG1-C, complete cds. [AB007457] 2.44 0.011698965 AK096674 AK096674 Homo sapiens cDNA FLJ39355 fis, clone PEBLM2003426. [AK096674] c50-1 cDNA subtractive library of rectum adencarcinoma Homo sapiens cDNA, mRNA 2.42 0.034978166 CK570365 CK570365 sequence [CK570365]

Q8C2Q7_MOUSE (Q8C2Q7) 2 days neonate thymic cells cDNA, RIKEN full-length 2.42 0.037031095 THC2563549 enriched library, clone:E430005G16 :heterogeneous nuclear ribonucleoprotein H1, full insert sequence (Heterogeneous nuclear ribonucleoprotein H1), partial (7%)...

AA593970 nn01c05.s1 NCI_CGAP_Co9 Homo sapiens cDNA clone IMAGE:1076456 3', mRNA 2.41 0.031489965 AA593970 AA593970 sequence [AA593970] Q4RCF0_TETNG (Q4RCF0) Chromosome undetermined SCAF19066, whole shotgun 2.39 0.014800362 THC2552359 sequence. (Fragment), partial (5%) [THC2552359] zw44b06.s1 Soares_total_fetus_Nb2HF8_9w Homo sapiens cDNA clone IMAGE:772883 3', 2.39 0.022330765 AA479896 AA479896 mRNA sequence [AA479896] PREDICTED: Homo sapiens hypothetical protein LOC730589 (LOC730589), mRNA 2.37 0.02755359 XM_001126447 LOC730589 [XM_001126447] Homo sapiens interferon-induced protein with tetratricopeptide repeats 3 (IFIT3), mRNA 2.36 0.035724793 NM_001549 IFIT3 [NM_001549] 2.34 0.014170392 NM_000446 PON1 Homo sapiens paraoxonase 1 (PON1), mRNA [NM_000446] 2.33 0.03818243 NM_014454 SESN1 Homo sapiens sestrin 1 (SESN1), mRNA [NM_014454] 2.31 0.029248085 NM_004760 STK17A Homo sapiens / 17a (STK17A), mRNA [NM_004760] 2.31 0.009740621 THC2682291 2.30 0.037122253 A_32_P2303 2.30 0.04984276 A_32_P20040 2.28 0.004130933 NM_000107 DDB2 Homo sapiens damage-specific DNA binding protein 2, 48kDa (DDB2), mRNA [NM_000107] 2.25 0.024709743 THC2603717 Q8WNW4_PIG (Q8WNW4) Beta-catenin, partial (11%) [THC2603717] 2.24 0.029112116 NM_018284 GBP3 Homo sapiens guanylate binding protein 3 (GBP3), mRNA [NM_018284] 2.21 0.027972294 NM_017860 C1orf56 Homo sapiens open reading frame 56 (C1orf56), mRNA [NM_017860] 2.21 0.019145912 AF318360 MNT Homo sapiens pp7518 mRNA, complete cds. [AF318360] 2.20 0.00501392 NM_032420 PCDH1 Homo sapiens protocadherin 1 (PCDH1), transcript variant 2, mRNA [NM_032420] BE825944 CM2-EN0014-310500-207-g07 EN0014 Homo sapiens cDNA, mRNA sequence 2.17 0.007026038 BE825944 BE825944 [BE825944] Homo sapiens cDNA: FLJ21978 fis, clone HEP06046, highly similar to AF158185 Homo sapiens 2.16 0.034157425 AK025631 POLH xeroderma pigmentosum variant RAD30 (RAD30) mRNA. [AK025631] 2.14 9.74E-04 AK022045 AK022045 Homo sapiens cDNA FLJ11983 fis, clone HEMBB1001337. [AK022045] BQ777622 il38g05.x1 HR85 islet Homo sapiens cDNA clone IMAGE:6032433 3', mRNA 2.14 0.017722348 BQ777622 BQ777622 sequence [BQ777622] Homo sapiens coiled-coil domain containing 50 (CCDC50), transcript variant 1, mRNA 2.14 0.015631802 NM_174908 CCDC50 [NM_174908] Homo sapiens hypothetical protein MGC5370, mRNA (cDNA clone IMAGE:3049213), partial cds. 2.13 0.004999394 BC006795 MGC5370 [BC006795] BX457728 BX457728 Homo sapiens NEUROBLASTOMA Homo sapiens cDNA clone 2.13 0.029858643 BX457728 BX457728 CS0DA003YD09 3-PRIME, mRNA sequence [BX457728] 2.13 0.011983706 NM_015073 SIPA1L3 Homo sapiens signal-induced proliferation-associated 1 like 3 (SIPA1L3), mRNA [NM_015073]

Homo sapiens cyclin-dependent kinase inhibitor 1A (p21, Cip1) (CDKN1A), transcript variant 2, 2.10 0.028276982 NM_078467 CDKN1A mRNA [NM_078467] BM680083 UI-E-EO1-aix-j-14-0-UI.s1 UI-E-EO1 Homo sapiens cDNA clone UI-E-EO1-aix-j-14- 2.10 0.024368802 BM680083 BM680083 0-UI 3', mRNA sequence [BM680083] 2.10 6.93E-04 NM_018194 HHAT Homo sapiens hedgehog acyltransferase (HHAT), mRNA [NM_018194] 2.09 0.028718991 THC2545454 AI685431 tt88b11.x1 NCI_CGAP_Pr28 Homo sapiens cDNA clone IMAGE:2248605 3', mRNA 2.08 0.018992158 AI685431 AI685431 sequence [AI685431] 2.07 0.0351539 NM_139072 DNER Homo sapiens delta/notch-like EGF repeat containing (DNER), mRNA [NM_139072] 2.05 0.04175851 NM_001454 FOXJ1 Homo sapiens forkhead box J1 (FOXJ1), mRNA [NM_001454] Homo sapiens ferredoxin reductase (FDXR), nuclear gene encoding mitochondrial protein, 2.03 8.05E-04 NM_024417 FDXR transcript variant 1, mRNA [NM_024417] AA890297 aj94e10.s1 Soares_parathyroid_tumor_NbHPA Homo sapiens cDNA clone 2.01 0.034785107 THC2780391 IMAGE:1404138 3', mRNA sequence [AA890297] BX427588 Homo sapiens FETAL Homo sapiens cDNA clone CS0DM011YM01 3- 2.01 0.019359725 BX427588 BX427588 PRIME, mRNA sequence [BX427588] 2.00 0.002368347 NM_004073 PLK3 Homo sapiens polo-like kinase 3 () (PLK3), mRNA [NM_004073] 2.00 0.0364692 AB007456 TP53AP1 Homo sapiens mRNA for P53TG1-B, complete cds. [AB007456] BF822111 CM3-RT0011-051200-531-f10 RT0011 Homo sapiens cDNA, mRNA sequence 1.98 0.028169021 BF822111 BF822111 [BF822111] Uncharacterized protein C10orf11. [Source:Uniprot/SWISSPROT;Acc:Q9H2I8] 1.96 0.031099848 ENST00000354343 [ENST00000354343] AV742170 AV742170 CB Homo sapiens cDNA clone CBFBRD03 5', mRNA sequence 1.95 0.028466815 AV742170 AV742170 [AV742170] 1.95 0.011248466 NM_007237 SP140 Homo sapiens SP140 nuclear body protein (SP140), transcript variant 1, mRNA [NM_007237] 1.95 0.03941059 A_24_P916853 Homo sapiens MADS box enhancer factor 2, polypeptide C (myocyte enhancer factor 1.93 0.002391394 NM_002397 MEF2C 2C) (MEF2C), mRNA [NM_002397] 1.93 0.01918256 NM_005755 EBI3 Homo sapiens Epstein-Barr virus induced gene 3 (EBI3), mRNA [NM_005755] Homo sapiens biogenesis of lysosome-related organelles complex-1, subunit 2 (BLOC1S2), 1.91 0.029184025 NM_001001342 BLOC1S2 transcript variant 2, mRNA [NM_001001342] 1.91 0.004666783 NM_020478 ANK1 Homo sapiens 1, erythrocytic (ANK1), transcript variant 5, mRNA [NM_020478] 1.90 0.046981405 NM_000951 PRRG2 Homo sapiens rich Gla (G-carboxyglutamic acid) 2 (PRRG2), mRNA [NM_000951] 1.90 0.036747605 NM_003566 EEA1 Homo sapiens early endosome 1 (EEA1), mRNA [NM_003566] 1.89 0.018708188 NM_022772 EPS8L2 Homo sapiens EPS8-like 2 (EPS8L2), mRNA [NM_022772] Homo sapiens biogenesis of lysosome-related organelles complex-1, subunit 2 (BLOC1S2), 1.89 0.021714017 NM_001001342 BLOC1S2 transcript variant 2, mRNA [NM_001001342] AI431972 th32h07.x1 NCI_CGAP_Pan1 Homo sapiens cDNA clone IMAGE:2120029 3', mRNA 1.88 0.034058664 AI431972 AI431972 sequence [AI431972] 1.87 9.75E-04 NM_145172 WDR63 Homo sapiens WD repeat domain 63 (WDR63), mRNA [NM_145172] 1.87 0.04553351 A_32_P167212 Serine/threonine- MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase 1.86 0.006770601 CDC42BPG gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).... 1.85 0.039723884 NM_018569 C4orf16 Homo sapiens open reading frame 16 (C4orf16), mRNA [NM_018569] 1.85 0.012218618 NM_016084 RASD1 Homo sapiens RAS, dexamethasone-induced 1 (RASD1), mRNA [NM_016084] 1.85 0.00452887 NM_018965 TREM2 Homo sapiens triggering receptor expressed on myeloid cells 2 (TREM2), mRNA [NM_018965] 1.84 0.048950966 NM_003225 TFF1 Homo sapiens trefoil factor 1 (TFF1), mRNA [NM_003225] 1.82 0.012305332 NM_003196 TCEA3 Homo sapiens transcription elongation factor A (SII), 3 (TCEA3), mRNA [NM_003196] BQ015182 UI-H-ED1-axw-m-24-0-UI.s1 NCI_CGAP_ED1 Homo sapiens cDNA clone 1.82 0.022849482 BQ015182 BQ015182 IMAGE:5834687 3', mRNA sequence [BQ015182] 1.81 0.01843371 NM_003463 PTP4A1 Homo sapiens protein phosphatase type IVA, member 1 (PTP4A1), mRNA [NM_003463] 1.81 0.043048777 THC2668359 1.81 0.04276675 NM_004999 MYO6 Homo sapiens myosin VI (MYO6), mRNA [NM_004999] 1.80 0.033776183 NM_015073 SIPA1L3 Homo sapiens signal-induced proliferation-associated 1 like 3 (SIPA1L3), mRNA [NM_015073]

Homo sapiens cyclin-dependent kinase inhibitor 1A (p21, Cip1) (CDKN1A), transcript variant 1, 1.80 0.025760477 NM_000389 CDKN1A mRNA [NM_000389] 1.79 0.0356997 THC2498220 Q30VC0_DESDG (Q30VC0) Flagellar biosynthetic protein FliP, partial (8%) [THC2498220]

ALU6_HUMAN (P39193) Alu subfamily SP sequence contamination warning entry, partial (4%) 1.78 0.023408463 THC2736955 [THC2736955] 1.78 0.017179344 BC015064 TOB1 Homo sapiens, clone IMAGE:4133978, mRNA. [BC015064] 1.77 0.019758811 NM_006493 CLN5 Homo sapiens ceroid-lipofuscinosis, neuronal 5 (CLN5), mRNA [NM_006493] 1.77 0.028448557 NM_005143 HP Homo sapiens haptoglobin (HP), mRNA [NM_005143] 1.76 0.023612952 A_32_P169353 AI344752 qp05c06.x1 NCI_CGAP_Kid5 Homo sapiens cDNA clone IMAGE:1917130 3', mRNA 1.76 0.032938544 AI344752 AI344752 sequence [AI344752] 1.75 0.037619956 NM_020375 C12orf5 Homo sapiens chromosome 12 open reading frame 5 (C12orf5), mRNA [NM_020375] 1.75 0.03141247 NM_145025 C6orf199 Homo sapiens open reading frame 199 (C6orf199), mRNA [NM_145025] 1.74 0.036635008 NM_018837 SULF2 Homo sapiens 2 (SULF2), transcript variant 1, mRNA [NM_018837] 1.74 0.037003297 NM_004999 MYO6 Homo sapiens myosin VI (MYO6), mRNA [NM_004999] Homo sapiens sialic acid binding Ig-like lectin 7 (SIGLEC7), transcript variant 2, mRNA 1.74 0.047374766 NM_016543 SIGLEC7 [NM_016543] Homo sapiens neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1) (NCF1), 1.73 0.03210656 NM_000265 NCF1 mRNA [NM_000265] 1.73 0.04786841 NM_000110 DPYD Homo sapiens dihydropyrimidine dehydrogenase (DPYD), mRNA [NM_000110] Homo sapiens open reading frame 36 (C19orf36), transcript variant 1, mRNA 1.73 0.031828295 NM_001031735 C19orf36 [NM_001031735] transmembrane and tetratricopeptide repeat containing 3 [Source:RefSeq_peptide;Acc:NP_861448] 1.73 0.03396063 TMTC3 [ENST00000266712] AI167420 ox69h05.s1 Soares_NhHMPu_S1 Homo sapiens cDNA clone IMAGE:1661625 3', 1.72 0.021538123 AI167420 AI167420 mRNA sequence [AI167420] Homo sapiens Mdm2, transformed 3T3 cell double minute 2, p53 binding protein () 1.71 0.022860808 NM_002392 MDM2 (MDM2), transcript variant MDM2, mRNA [NM_002392] Homo sapiens activating signal cointegrator 1 complex subunit 3 (ASCC3), transcript variant 1, 1.69 0.008165966 NM_006828 ASCC3 mRNA [NM_006828] 1.68 0.02445084 A_32_P135489 1.67 0.04068673 THC2596018 Q99834_HUMAN (Q99834) Nuclear antigen H731, partial (21%) [THC2580379] AW804939 QV4-UM0094-060400-159-g07 UM0094 Homo sapiens cDNA, mRNA sequence 1.67 0.015224122 AW804939 AW804939 [AW804939] 1.67 0.0429934 AK096327 LOC162073 Homo sapiens cDNA FLJ39008 fis, clone NT2RI2025255. [AK096327] Homo sapiens tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript 1.67 0.025220597 NM_003842 TNFRSF10B variant 1, mRNA [NM_003842] 1.65 0.014965225 NM_198859 PRICKLE2 Homo sapiens prickle homolog 2 (Drosophila) (PRICKLE2), mRNA [NM_198859] 1.64 0.03770175 NM_006086 TUBB3 Homo sapiens tubulin, beta 3 (TUBB3), mRNA [NM_006086] zl48e07.s1 Soares_pregnant_uterus_NbHPU Homo sapiens cDNA clone IMAGE:505188 3', 1.64 0.011121801 AA151106 AA151106 mRNA sequence [AA151106] 1.64 0.04793037 NM_006915 RP2 Homo sapiens retinitis pigmentosa 2 (X-linked recessive) (RP2), mRNA [NM_006915] 1.64 0.002596203 NM_152890 COL24A1 Homo sapiens collagen, type XXIV, alpha 1 (COL24A1), mRNA [NM_152890] 1.64 0.015165447 THC2563238 CF529502 UI-1-BC1p-ash-d-10-0-UI.s1 NCI_CGAP_Pl3 Homo sapiens cDNA clone UI-1-BC1p- 1.64 0.027577512 CF529502 CF529502 ash-d-10-0-UI 3', mRNA sequence [CF529502] Homo sapiens plectin 1, intermediate filament binding protein 500kDa (PLEC1), transcript variant 1.63 0.012595186 NM_201384 PLEC1 11, mRNA [NM_201384] 1.63 0.02996702 A_32_P136575 1.62 0.00954439 BC017654 LOC440498 Homo sapiens cDNA clone IMAGE:3887603. [BC017654] 1.62 0.041373413 NM_014397 NEK6 Homo sapiens NIMA (never in mitosis gene a)-related kinase 6 (NEK6), mRNA [NM_014397] 1.62 0.018584888 NM_013444 UBQLN2 Homo sapiens ubiquilin 2 (UBQLN2), mRNA [NM_013444] Homo sapiens elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3 1.62 0.0366129 NM_152310 ELOVL3 (ELOVL3), mRNA [NM_152310] AI570240 to76g03.x1 NCI_CGAP_Gas4 Homo sapiens cDNA clone IMAGE:2184244 3', mRNA 1.61 0.030700862 AI570240 AI570240 sequence [AI570240] 1.61 0.03458113 NM_016551 TM7SF3 Homo sapiens transmembrane 7 superfamily member 3 (TM7SF3), mRNA [NM_016551] 1.61 0.021008106 NM_002178 IGFBP6 Homo sapiens insulin-like growth factor binding protein 6 (IGFBP6), mRNA [NM_002178]

Seven transmembrane helix receptor. [Source:Uniprot/SPTREMBL;Acc:Q8NH77] 1.61 0.014409732 ENST00000316517 [ENST00000316517] Homo sapiens LATS, large tumor suppressor, homolog 2 (Drosophila) (LATS2), mRNA 1.60 0.042853776 NM_014572 LATS2 [NM_014572] Homo sapiens chromosome 1 open reading frame 183 (C1orf183), transcript variant 1, mRNA 1.60 0.034304716 NM_019099 C1orf183 [NM_019099] Homo sapiens family with sequence similarity 111, member A (FAM111A), transcript variant 1, 1.59 0.031976018 NM_022074 FAM111A mRNA [NM_022074] 1.58 0.007696148 NM_033083 EAF1 Homo sapiens ELL associated factor 1 (EAF1), mRNA [NM_033083] 1.58 0.049492475 NM_019600 KIAA1370 Homo sapiens KIAA1370 (KIAA1370), mRNA [NM_019600] 1.58 0.029621134 NM_001621 AHR Homo sapiens aryl hydrocarbon receptor (AHR), mRNA [NM_001621] 1.58 0.005517118 BC041926 BC041926 Homo sapiens cDNA clone IMAGE:5300349. [BC041926] 1.58 0.006248204 NM_032228 MLSTD2 Homo sapiens male sterility domain containing 2 (MLSTD2), mRNA [NM_032228] fg05b07.y1 Human Iris cDNA (Normalized): fg Homo sapiens cDNA clone fg05b07 5', mRNA 1.57 0.030305423 CD671494 CD671494 sequence [CD671494] 1.57 0.00630087 NM_016479 SCOTIN Homo sapiens scotin (SCOTIN), mRNA [NM_016479] 1.56 0.028182587 AF242771 AF242771 Homo sapiens mesenchymal stem cell protein DSC96 mRNA, partial cds. [AF242771] 1.55 0.035055354 NM_014172 PHPT1 Homo sapiens phosphohistidine phosphatase 1 (PHPT1), mRNA [NM_014172] 1.55 0.023526678 A_23_P21804 1.55 0.039897073 NM_013275 ANKRD11 Homo sapiens ankyrin repeat domain 11 (ANKRD11), mRNA [NM_013275] Homo sapiens Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 (RAPH1), 1.55 0.043389257 NM_213589 RAPH1 transcript variant 1, mRNA [NM_213589] 1.55 0.03245712 NM_031216 SEH1L Homo sapiens SEH1-like (S. cerevisiae) (SEH1L), transcript variant 2, mRNA [NM_031216] 1.53 0.003701655 NM_015137 KIAA0143 Homo sapiens KIAA0143 protein (KIAA0143), mRNA [NM_015137] Homo sapiens eukaryotic translation initiation factor 4A, isoform 2, mRNA (cDNA clone 1.53 0.044266894 BC039344 EIF4A2 IMAGE:5269135). [BC039344] 1.53 0.01161285 NM_178828 C9orf79 Homo sapiens open reading frame 79 (C9orf79), mRNA [NM_178828] 1.53 0.040241756 NM_153226 TMEM20 Homo sapiens transmembrane protein 20 (TMEM20), mRNA [NM_153226] BM997687 UI-H-DH0-aus-i-05-0-UI.s1 NCI_CGAP_DH0 Homo sapiens cDNA clone 1.52 0.04400178 BM997687 BM997687 IMAGE:5873740 3', mRNA sequence [BM997687] 1.51 0.007925773 THC2708262 1.51 0.004124573 NM_018058 CRTAC1 Homo sapiens cartilage acidic protein 1 (CRTAC1), mRNA [NM_018058] 1.51 0.046705034 CN277024 CN277024 17000600173672 GRN_PREHEP Homo sapiens cDNA 5', mRNA sequence [CN277024] 1.51 0.024238542 THC2610890 Q54TC3_DICDI (Q54TC3) FVYE domain-containing protein, partial (3%) [THC2610890] 1.51 0.034981854 NM_020406 CD177 Homo sapiens CD177 molecule (CD177), mRNA [NM_020406] 1.51 0.01564413 NM_004120 GBP2 Homo sapiens guanylate binding protein 2, interferon-inducible (GBP2), mRNA [NM_004120] 1.50 0.03894739 NM_004343 CALR Homo sapiens calreticulin (CALR), mRNA [NM_004343] 1.50 0.0173163 BC020539 BC020539 Homo sapiens, clone IMAGE:3048919, mRNA, partial cds. [BC020539] BQ339228 MR0-NN0190-281000-202-f11 NN0190 Homo sapiens cDNA, mRNA sequence 1.49 0.009972722 BQ339228 BQ339228 [BQ339228] 1.49 0.02522183 NM_030657 LIM2 Homo sapiens lens intrinsic membrane protein 2, 19kDa (LIM2), mRNA [NM_030657] Homo sapiens vasodilator-stimulated phosphoprotein (VASP), transcript variant 1, mRNA 1.49 0.007979681 NM_003370 VASP [NM_003370] Homo sapiens NAD(P)H dehydrogenase, 1 (NQO1), transcript variant 1, mRNA 1.49 0.043911204 NM_000903 NQO1 [NM_000903] 1.48 0.012996967 NM_201555 FHL2 Homo sapiens four and a half LIM domains 2 (FHL2), transcript variant 2, mRNA [NM_201555] 1.48 0.01600929 NM_032704 TUBA1C Homo sapiens tubulin, alpha 1c (TUBA1C), mRNA [NM_032704] BU678941 UI-CF-DU1-aat-a-09-0-UI.s1 UI-CF-DU1 Homo sapiens cDNA clone UI-CF-DU1-aat- 1.48 0.033916257 THC2680668 a-09-0-UI 3', mRNA sequence [BU678941] 1.48 0.034301702 AB037781 SCYL2 Homo sapiens mRNA for KIAA1360 protein, partial cds. [AB037781] Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation 1.48 0.010984946 TAF3 factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140). [Source:Uniprot/SWISSPROT;Acc:Q5VWG9]... 1.47 0.04508368 BC070369 BC070369 Homo sapiens cDNA clone IMAGE:6622137, partial cds. [BC070369] 1.47 0.008797976 NM_003196 TCEA3 Homo sapiens transcription elongation factor A (SII), 3 (TCEA3), mRNA [NM_003196] 1.47 0.012957469 NM_014734 KIAA0247 Homo sapiens KIAA0247 (KIAA0247), mRNA [NM_014734] 1.46 0.010949053 THC2666469 1.46 0.012996607 AK090467 LOC284542 Homo sapiens mRNA for FLJ00388 protein. [AK090467] 1.46 0.03523826 NM_000076 CDKN1C Homo sapiens cyclin-dependent kinase inhibitor 1C (p57, Kip2) (CDKN1C), mRNA [NM_000076] UI-E-CI0-aac-g-02-0-UI.s1 UI-E-CI0 Homo sapiens cDNA clone UI-E-CI0-aac-g-02-0-UI 3', 1.46 0.02236027 BU726029 BU726029 mRNA sequence [BU726029] Homo sapiens runt-related 1 ( 1; aml1 oncogene) 1.46 0.006678154 NM_001001890 RUNX1 (RUNX1), transcript variant 2, mRNA [NM_001001890] 1.46 0.03436765 NM_001039775 FLJ38020 Homo sapiens similar to absent in 1 (FLJ38020), mRNA [NM_001039775] 1.46 0.004259078 NM_001755 CBFB Homo sapiens core-binding factor, beta subunit (CBFB), transcript variant 2, mRNA [NM_001755]

Homo sapiens similar to RPL23AP7 protein (MGC70863), transcript variant 2, mRNA 1.45 0.032798544 NM_203302 MGC70863 [NM_203302] Homo sapiens potassium channel tetramerisation domain containing 10 (KCTD10), mRNA 1.45 0.04444794 NM_031954 KCTD10 [NM_031954] Homo sapiens - crosslinking factor 1 (MACF1), transcript variant 2, mRNA 1.45 0.022945974 NM_033044 MACF1 [NM_033044] 1.44 0.0247215 AF086335 AF086335 Homo sapiens full length insert cDNA clone ZD55G10. [AF086335] 1.44 0.019268857 NM_017622 C17orf59 Homo sapiens open reading frame 59 (C17orf59), mRNA [NM_017622] Homo sapiens solute carrier family 7 (cationic transporter, y+ system), member 8 1.44 0.036932748 NM_182728 SLC7A8 (SLC7A8), transcript variant 2, mRNA [NM_182728] 1.44 0.031719368 NM_015443 KIAA1267 Homo sapiens KIAA1267 (KIAA1267), mRNA [NM_015443] 1.44 0.041345976 AK023086 AK023086 Homo sapiens cDNA FLJ13024 fis, clone NT2RP3000865. [AK023086] Homo sapiens keratinocyte growth factor-like protein 1, mRNA (cDNA clone MGC:126891 1.44 0.012616136 BC101842 KGFLP1 IMAGE:8069348), complete cds. [BC101842] 1.44 0.002781811 NM_020245 TULP4 Homo sapiens tubby like protein 4 (TULP4), transcript variant 1, mRNA [NM_020245] BU618279 UI-H-FH1-bfh-m-09-0-UI.s1 NCI_CGAP_FH1 Homo sapiens cDNA clone UI-H-FH1- 1.44 3.60E-04 BU618279 BU618279 bfh-m-09-0-UI 3', mRNA sequence [BU618279] Homo sapiens v-ral simian leukemia viral oncogene homolog A (ras related) (RALA), mRNA 1.43 0.014121237 NM_005402 RALA [NM_005402] 1.43 0.006622754 NM_017798 YTHDF1 Homo sapiens YTH domain family, member 1 (YTHDF1), mRNA [NM_017798] aa22e03.s1 NCI_CGAP_GCB1 Homo sapiens cDNA clone IMAGE:814012 3', mRNA sequence 1.42 0.009174091 AA455656 AA455656 [AA455656] Homo sapiens NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa (NDUFB2), nuclear 1.42 0.011034809 NM_004546 NDUFB2 gene encoding mitochondrial protein, mRNA [NM_004546] 1.41 0.04693434 NM_003196 TCEA3 Homo sapiens transcription elongation factor A (SII), 3 (TCEA3), mRNA [NM_003196] 1.41 0.011576547 AK057015 AK057015 Homo sapiens cDNA FLJ32453 fis, clone SKMUS2001703. [AK057015] 1.41 0.03275642 A_24_P7494 1.41 0.04931042 NM_014501 UBE2S Homo sapiens -conjugating E2S (UBE2S), mRNA [NM_014501] 1.41 0.02704917 NM_015154 MESDC2 Homo sapiens mesoderm development candidate 2 (MESDC2), mRNA [NM_015154] 1.40 0.039335422 NM_003142 SSB Homo sapiens Sjogren syndrome antigen B (autoantigen La) (SSB), mRNA [NM_003142] 1.40 0.013260856 LIX1L LIX1-like protein. [Source:Uniprot/SWISSPROT;Acc:Q8IVB5] [ENST00000369308] 1.40 0.039146196 NM_144602 C16orf78 Homo sapiens open reading frame 78 (C16orf78), mRNA [NM_144602] Homo sapiens iron-sulfur cluster scaffold homolog (E. coli) (ISCU), nuclear gene encoding 1.40 0.030726723 NM_014301 ISCU mitochondrial protein, transcript variant 1, mRNA [NM_014301] 1.40 0.03249179 NM_005955 MTF1 Homo sapiens metal-regulatory transcription factor 1 (MTF1), mRNA [NM_005955] -1.40 3.95E-02 ENST00000342893 Homo sapiens natural killer-tumor recognition sequence (NKTR), transcript variant 2, mRNA -1.40 6.18E-03 NM_001012651 NKTR [NM 001012651] BC037545 poly(ADP-ribosyl) {Homo sapiens} (exp=-1; wgp=0; cg=0), partial (24%) -1.40 3.41E-02 THC2762149 [THC2762149] -1.40 1.06E-02 NM_001005 RPS3 Homo sapiens ribosomal protein S3 (RPS3), mRNA [NM_001005] Homo sapiens Wolf-Hirschhorn syndrome candidate 1 (WHSC1), transcript variant 7, mRNA -1.40 3.58E-02 NM_133334 WHSC1 [NM 133334] -1.40 4.27E-02 NM_152331 ACOT4 Homo sapiens acyl-CoA 4 (ACOT4), mRNA [NM_152331] Homo sapiens solute carrier family 5 (sodium/glucose cotransporter), member 12 (SLC5A12), transcript -1.41 2.19E-03 NM_178498 SLC5A12 variant 2, mRNA [NM 178498] Homo sapiens phosphoribosyl pyrophosphate synthetase 2 (PRPS2), transcript variant 2, mRNA -1.41 4.31E-02 NM_002765 PRPS2 [NM 002765] Homo sapiens inositol polyphosphate-5-phosphatase, 75kDa (INPP5B), nuclear gene encoding -1.41 2.62E-02 NM_005540 INPP5B mitochondrial protein, mRNA [NM 005540] -1.41 3.16E-02 NM_177559 CSNK2A1 Homo sapiens , alpha 1 polypeptide (CSNK2A1), transcript variant 1, mRNA [NM_177559] family with sequence similarity 63, member A (FAM63A), transcript variant 1, mRNA -1.41 1.74E-02 FAM63A [Source:RefSeq ;Acc:NM 018379] [ENST00000368945] -1.41 3.08E-02 THC2665933 Q5NNJ5_ZYMMO (Q5NNJ5) DNA polymerase III delta prime subunit , partial (5%) [THC2665933] -1.41 2.51E-02 NM_015654 NAT9 Homo sapiens N-acetyltransferase 9 (NAT9), mRNA [NM_015654] -1.41 4.25E-02 THC2560098 S35960 C-terminal {Homo sapiens} (exp=-1; wgp=0; cg=0), partial (64%) [THC2560098] -1.41 4.50E-02 CR936613 KIAA1109 Homo sapiens mRNA; cDNA DKFZp781P0474 (from clone DKFZp781P0474). [CR936613] -1.42 1.18E-02 NM_133458 ZFP90 Homo sapiens protein 90 homolog (mouse) (ZFP90), mRNA [NM_133458] -1.42 2.72E-02 NM_017904 TTC22 Homo sapiens tetratricopeptide repeat domain 22 (TTC22), mRNA [NM_017904] AI910722 wg94h08.x1 NCI_CGAP_Kid11 Homo sapiens cDNA clone IMAGE:2378943 3', mRNA -1.42 1.57E-02 AI910722 AI910722 sequence [AI910722] -1.42 4.94E-02 NM_052903 TUBGCP5 Homo sapiens tubulin, gamma complex associated protein 5 (TUBGCP5), mRNA [NM_052903] -1.42 4.98E-02 NM_003875 GMPS Homo sapiens monphosphate synthetase (GMPS), mRNA [NM_003875] PREDICTED: Homo sapiens similar to 60S ribosomal protein L10 (QM protein) (Tumor suppressor QM) -1.42 9.50E-03 XM_928025 LOC644937 (Laminin receptor homolog) (LOC644937), mRNA [XM 928025] Homo sapiens beta-1,3-glucuronyltransferase 1 ( P) (B3GAT1), transcript variant 1, -1.43 3.76E-02 NM_018644 B3GAT1 mRNA [NM 018644] -1.43 1.99E-02 XR_018574 LOC402214 PREDICTED: Homo sapiens hypothetical LOC402214 (LOC402214), mRNA [XR_018574] -1.43 4.71E-03 BC000227 LOC284600 Homo sapiens, Similar to hypothetical protein FLJ11267, clone IMAGE:3350725, mRNA. [BC000227] -1.44 4.75E-02 NM_022756 C1orf149 Homo sapiens chromosome 1 open reading frame 149 (C1orf149), mRNA [NM_022756] PREDICTED: Homo sapiens similar to acidic ribosomal phosphoprotein P0 (LOC648633), mRNA -1.44 3.84E-02 XR_018427 LOC648633 [XR 018427] -1.44 3.04E-02 NM_031482 ATG10 Homo sapiens ATG10 autophagy related 10 homolog (S. cerevisiae) (ATG10), mRNA [NM_031482] -1.44 3.50E-02 NM_000170 GLDC Homo sapiens dehydrogenase (decarboxylating) (GLDC), mRNA [NM_000170] -1.44 1.21E-02 NM_004890 SPAG7 Homo sapiens sperm associated antigen 7 (SPAG7), mRNA [NM_004890] -1.44 2.92E-03 NM_022662 ANAPC1 Homo sapiens anaphase promoting complex subunit 1 (ANAPC1), mRNA [NM_022662] Homo sapiens MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) associated protein antisense -1.44 4.86E-02 NR_002776 MCM3APAS (MCM3APAS) on chromosome 21 [NR 002776] -1.44 4.48E-02 NM_001005 RPS3 Homo sapiens ribosomal protein S3 (RPS3), mRNA [NM_001005] -1.44 2.05E-02 NM_153712 TTL Homo sapiens tubulin tyrosine (TTL), mRNA [NM_153712] -1.45 3.50E-02 NM_004796 NRXN3 Homo sapiens neurexin 3 (NRXN3), transcript variant alpha, mRNA [NM_004796] -1.45 1.70E-02 NM_006479 RAD51AP1 Homo sapiens RAD51 associated protein 1 (RAD51AP1), mRNA [NM_006479] -1.45 2.42E-02 NM_024018 BTN2A3 Homo sapiens butyrophilin, subfamily 2, member A3 (BTN2A3), mRNA [NM_024018] -1.45 1.82E-02 NM_018555 ZNF331 Homo sapiens zinc finger protein 331 (ZNF331), transcript variant 1, mRNA [NM_018555] W18193 IMAGE:20064 Soares infant brain 1NIB Homo sapiens cDNA clone IMAGE:20064, mRNA -1.45 3.97E-02 THC2567672 sequence [W18193] -1.45 4.59E-02 NM_003635 NDST2 Homo sapiens N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 (NDST2), mRNA [NM_003635] BX110908 Soares_testis_NHT Homo sapiens cDNA clone IMAGp998G162577, mRNA sequence -1.45 4.46E-02 BX110908 BX110908 [BX110908] -1.46 3.89E-02 NM_016166 PIAS1 Homo sapiens protein inhibitor of activated STAT, 1 (PIAS1), mRNA [NM_016166] HUMC4AA2 complement component C4A {Homo sapiens} (exp=-1; wgp=0; cg=0), partial (6%) -1.46 4.28E-02 THC2527772 [THC2527772] -1.47 2.64E-03 NM_000396 CTSK Homo sapiens K (CTSK), mRNA [NM_000396] -1.47 3.19E-02 BF767798 BF767798 BF767798 CM1-CN0060-201200-680-c04 CN0060 Homo sapiens cDNA, mRNA sequence [BF767798] -1.47 9.95E-03 AW994037 AW994037 AW994037 RC3-BN0036-090200-011-f03 BN0036 Homo sapiens cDNA, mRNA sequence [AW994037] -1.47 2.24E-02 NM_002220 ITPKA Homo sapiens inositol 1,4,5-trisphosphate 3-kinase A (ITPKA), mRNA [NM_002220] Homo sapiens similar to Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16), -1.48 1.71E-02 BC110641 MGC102966 mRNA (cDNA clone MGC:102966 IMAGE:4752428), complete cds. [BC110641] -1.48 2.31E-02 NM_178526 SLC25A42 Homo sapiens solute carrier family 25, member 42 (SLC25A42), mRNA [NM_178526] -1.48 4.00E-02 NM_032512 PDZD4 Homo sapiens PDZ domain containing 4 (PDZD4), mRNA [NM_032512] Homo sapiens gem (nuclear organelle) associated protein 8 (GEMIN8), transcript variant 3, mRNA -1.48 3.79E-02 NM_017856 GEMIN8 [NM 017856] -1.48 2.54E-02 NM_000425 L1CAM Homo sapiens (L1CAM), transcript variant 1, mRNA [NM_000425] -1.48 3.36E-03 THC2653012 Q4ZXZ3_PSEU2 (Q4ZXZ3) GtrA-like protein, partial (9%) [THC2653012] -1.48 3.04E-02 NM_024490 ATP10A Homo sapiens ATPase, Class V, type 10A (ATP10A), mRNA [NM_024490] -1.48 4.90E-02 XR_018868 LOC645000 PREDICTED: Homo sapiens similar to 40S ribosomal protein S3 (LOC645000), mRNA [XR_018868] -1.49 2.96E-03 NM_080746 RPL10L Homo sapiens ribosomal protein L10-like (RPL10L), mRNA [NM_080746] -1.49 8.16E-03 AK074447 FLJ23867 Homo sapiens cDNA FLJ23867 fis, clone LNG09729. [AK074447] -1.49 8.60E-03 NM_152989 SOX5 Homo sapiens SRY (sex determining region Y)-box 5 (SOX5), transcript variant 2, mRNA [NM_152989] -1.49 3.83E-02 CR749856 CR749856 Homo sapiens mRNA; cDNA DKFZp781I1252 (from clone DKFZp781I1252). [CR749856] -1.49 1.68E-02 NM_024323 C19orf57 Homo sapiens chromosome 19 open reading frame 57 (C19orf57), mRNA [NM_024323] -1.49 1.91E-02 NM_032603 LOXL3 Homo sapiens lysyl -like 3 (LOXL3), mRNA [NM_032603] -1.50 4.30E-02 NM_153712 TTL Homo sapiens tubulin tyrosine ligase (TTL), mRNA [NM_153712] -1.50 4.16E-02 XR_018944 LOC442171 PREDICTED: Homo sapiens similar to ribosomal protein L10 (LOC442171), mRNA [XR_018944] -1.50 9.31E-03 NM_030971 SFXN3 Homo sapiens sideroflexin 3 (SFXN3), mRNA [NM_030971] AA693695 zi55a03.s1 Soares_fetal_liver_spleen_1NFLS_S1 Homo sapiens cDNA clone IMAGE:434668 -1.50 1.00E-02 AA693695 AA693695 3', mRNA sequence [AA693695] -1.50 1.16E-02 NM_012304 FBXL7 Homo sapiens F-box and leucine-rich repeat protein 7 (FBXL7), mRNA [NM_012304] -1.51 3.71E-02 A_24_P482189 -1.51 2.12E-02 NM_017443 POLE3 Homo sapiens polymerase (DNA directed), epsilon 3 (p17 subunit) (POLE3), mRNA [NM_017443] -1.51 3.93E-02 NM_000791 DHFR Homo sapiens dihydrofolate reductase (DHFR), mRNA [NM_000791] Homo sapiens CD40 molecule, TNF receptor superfamily member 5 (CD40), transcript variant 1, mRNA -1.51 9.74E-03 NM_001250 CD40 [NM 001250] -1.52 3.66E-02 NM_130898 CREB3L4 Homo sapiens cAMP responsive element binding protein 3-like 4 (CREB3L4), mRNA [NM_130898] -1.52 7.48E-04 NM_016824 ADD3 Homo sapiens adducin 3 (gamma) (ADD3), transcript variant 1, mRNA [NM_016824] -1.52 4.31E-02 NM_001824 CKM Homo sapiens kinase, muscle (CKM), mRNA [NM_001824] -1.52 1.83E-02 THC2656826 -1.53 4.51E-02 NM_024804 ZNF669 Homo sapiens zinc finger protein 669 (ZNF669), mRNA [NM_024804] Homo sapiens TEA domain family member 1 (SV40 transcriptional enhancer factor) (TEAD1), mRNA -1.53 4.40E-02 NM_021961 TEAD1 [NM 021961] -1.53 2.40E-02 NM_017872 THG1L Homo sapiens tRNA- guanylyltransferase 1-like (S. cerevisiae) (THG1L), mRNA [NM_017872] -1.54 2.50E-02 NM_018088 FAM90A1 Homo sapiens family with sequence similarity 90, member A1 (FAM90A1), mRNA [NM_018088] -1.54 4.91E-02 NM_001658 ARF1 Homo sapiens ADP-ribosylation factor 1 (ARF1), transcript variant 4, mRNA [NM_001658] -1.54 3.03E-02 NM_032336 GINS4 Homo sapiens GINS complex subunit 4 (Sld5 homolog) (GINS4), mRNA [NM_032336] PREDICTED: Homo sapiens similar to 60S acidic ribosomal protein P0 (L10E) (LOC122589), mRNA -1.54 1.15E-02 XR_019444 LOC122589 [XR 019444] -1.54 2.31E-02 NM_003105 SORL1 Homo sapiens sortilin-related receptor, L(DLR class) A repeats-containing (SORL1), mRNA [NM_003105] -1.55 2.82E-02 NM_182612 PDDC1 Homo sapiens Parkinson disease 7 domain containing 1 (PDDC1), mRNA [NM_182612] -1.55 9.84E-03 NM_178837 C19orf51 Homo sapiens chromosome 19 open reading frame 51 (C19orf51), mRNA [NM_178837] -1.55 2.04E-02 NM_005126 NR1D2 Homo sapiens subfamily 1, group D, member 2 (NR1D2), mRNA [NM_005126] -1.55 4.05E-03 A_24_P650893 -1.55 4.15E-02 AK095678 FLJ38359 Homo sapiens cDNA FLJ38359 fis, clone FEBRA2000321. [AK095678] -1.56 4.56E-02 NM_031460 KCNK17 Homo sapiens potassium channel, subfamily K, member 17 (KCNK17), mRNA [NM_031460] -1.56 2.15E-02 NM_032293 GARNL3 Homo sapiens GTPase activating Rap/RanGAP domain-like 3 (GARNL3), mRNA [NM_032293] Homo sapiens F-box and WD repeat domain containing 8 (FBXW8), transcript variant 1, mRNA -1.57 1.72E-02 NM_153348 FBXW8 [NM 153348] -1.57 3.02E-02 AK000347 LAX1 Homo sapiens cDNA FLJ20340 fis, clone HEP12374. [AK000347] -1.58 3.88E-02 NM_138376 TTC5 Homo sapiens tetratricopeptide repeat domain 5 (TTC5), mRNA [NM_138376] -1.58 2.71E-02 BC042557 LOC120376 Homo sapiens hypothetical protein LOC120376, mRNA (cDNA clone IMAGE:4818566). [BC042557] -1.59 2.66E-02 BX649112 COBLL1 Homo sapiens mRNA; cDNA DKFZp686E02109 (from clone DKFZp686E02109). [BX649112] -1.59 3.51E-02 NM_001001664 LOC339745 Homo sapiens hypothetical protein LOC339745 (LOC339745), mRNA [NM_001001664] -1.59 2.36E-02 NM_138371 FAM113B Homo sapiens family with sequence similarity 113, member B (FAM113B), mRNA [NM_138371] -1.59 1.88E-04 NM_006013 RPL10 Homo sapiens ribosomal protein L10 (RPL10), mRNA [NM_006013] -1.59 3.80E-02 A_32_P108592 -1.59 3.67E-02 NM_201520 SLC25A35 Homo sapiens solute carrier family 25, member 35 (SLC25A35), mRNA [NM_201520] Homo sapiens open reading frame 119, mRNA (cDNA clone IMAGE:4745538), with -1.60 1.18E-02 BC039151 C20orf119 apparent retained . [BC039151] -1.60 4.78E-02 AF272377 AF272377 Homo sapiens clone 1370-48 MLL protein mRNA, partial cds. [AF272377] -1.60 2.41E-02 NM_198887 NUP43 Homo sapiens nucleoporin 43kDa (NUP43), transcript variant 1, mRNA [NM_198887] -1.60 1.18E-02 NM_175866 UHMK1 Homo sapiens U2AF homology motif (UHM) kinase 1 (UHMK1), mRNA [NM_175866] -1.62 6.25E-03 NM_024917 CXorf34 Homo sapiens chromosome X open reading frame 34 (CXorf34), mRNA [NM_024917] -1.62 1.29E-02 NM_021937 EEFSEC Homo sapiens eukaryotic elongation factor, selenocysteine-tRNA-specific (EEFSEC), mRNA [NM_021937]

-1.62 4.31E-02 NM_021723 ADAM22 Homo sapiens ADAM metallopeptidase domain 22 (ADAM22), transcript variant 1, mRNA [NM_021723] -1.62 2.83E-02 NM_173499 SPATA8 Homo sapiens spermatogenesis associated 8 (SPATA8), mRNA [NM_173499] -1.62 1.06E-02 THC2518705 -1.63 6.42E-03 NM_001010982 AFMID Homo sapiens (AFMID), mRNA [NM_001010982] -1.63 2.88E-02 NM_032454 STK19 Homo sapiens serine/threonine kinase 19 (STK19), transcript variant 2, mRNA [NM_032454] -1.63 3.21E-02 NM_012423 RPL13A Homo sapiens ribosomal protein L13a (RPL13A), mRNA [NM_012423] -1.63 9.79E-03 ENST00000372821 Polyadenylate-binding protein 1-like. [Source:Uniprot/SWISSPROT;Acc:Q4VXU2] [ENST00000372821] -1.63 4.13E-02 NM_001005336 DNM1 Homo sapiens dynamin 1 (DNM1), transcript variant 2, mRNA [NM_001005336] -1.64 6.01E-03 FAM90A9 -1.64 3.66E-02 NM_032292 GON4L Homo sapiens gon-4-like (C. elegans) (GON4L), transcript variant 2, mRNA [NM_032292] Homo sapiens regulatory factor X, 2 (influences HLA class II expression) (RFX2), transcript variant 1, -1.65 2.72E-02 NM_000635 RFX2 mRNA [NM 000635] -1.66 3.48E-02 AK123143 AK123143 Homo sapiens cDNA FLJ41148 fis, clone BRACE2037310. [AK123143] -1.67 3.82E-02 NM_017742 ZCCHC2 Homo sapiens zinc finger, CCHC domain containing 2 (ZCCHC2), mRNA [NM_017742] -1.67 4.98E-02 AB032985 NXPH3 Homo sapiens mRNA for KIAA1159 protein, partial cds. [AB032985] -1.67 2.70E-02 NM_205853 MUSTN1 Homo sapiens musculoskeletal, embryonic nuclear protein 1 (MUSTN1), mRNA [NM_205853] -1.68 1.83E-02 BG181200 BG181200 RST125 Athersys RAGE Library Homo sapiens cDNA, mRNA sequence [BG181200] -1.68 2.64E-02 NM_213596 FOXN4 Homo sapiens forkhead box N4 (FOXN4), mRNA [NM_213596] -1.71 2.41E-02 NM_178571 MGC51025 Homo sapiens hypothetical protein MGC51025 (MGC51025), mRNA [NM_178571] -1.71 3.66E-02 BC032332 BC032332 Homo sapiens cDNA clone MGC:40288 IMAGE:5169056, complete cds. [BC032332] -1.73 2.14E-02 NM_006322 TUBGCP3 Homo sapiens tubulin, gamma complex associated protein 3 (TUBGCP3), mRNA [NM_006322] -1.74 3.91E-02 NM_012282 KCNE1L Homo sapiens KCNE1-like (KCNE1L), mRNA [NM_012282] -1.74 4.66E-02 NM_033481 FBXO9 Homo sapiens F-box protein 9 (FBXO9), transcript variant 3, mRNA [NM_033481] -1.75 3.60E-02 A_24_P350008 -1.75 1.43E-02 NM_005524 HES1 Homo sapiens hairy and enhancer of split 1, (Drosophila) (HES1), mRNA [NM_005524] -1.76 3.37E-02 AB051491 KIAA1704 Homo sapiens mRNA for KIAA1704 protein, partial cds. [AB051491] -1.76 1.78E-02 AK098427 AK098427 Homo sapiens cDNA FLJ25561 fis, clone JTH02933. [AK098427] -1.76 4.94E-02 AB040932 NPLOC4 Homo sapiens mRNA for KIAA1499 protein, partial cds. [AB040932] Pre-B-cell leukemia transcription factor 1 ( protein PBX1) (Homeobox protein PRL). -1.78 3.98E-02 PBX1 [Source:Uniprot/SWISSPROT;Acc:P40424] [ENST00000328681] -1.79 4.10E-02 NM_022804 SNURF Homo sapiens SNRPN upstream reading frame (SNURF), transcript variant 2, mRNA [NM_022804] Homo sapiens solute carrier family 17 (anion/sugar transporter), member 5 (SLC17A5), mRNA -1.80 4.78E-02 NM_012434 SLC17A5 [NM 012434] -1.80 2.15E-02 A_24_P324644 -1.81 4.47E-02 XR_018808 LOC441641 PREDICTED: Homo sapiens similar to ribosomal protein L13A (LOC441641), mRNA [XR_018808] Homo sapiens amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen) (AMPH), -1.82 2.07E-02 NM_001635 AMPH transcript variant 1, mRNA [NM 001635] -1.83 3.18E-02 NM_021976 RXRB Homo sapiens , beta (RXRB), mRNA [NM_021976] -1.83 1.53E-02 A_24_P341731 AI919230 qy30h02.x1 NCI_CGAP_Brn23 Homo sapiens cDNA clone IMAGE:2013555 3', mRNA -1.83 1.54E-02 AI919230 AI919230 sequence [AI919230] Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 4, mRNA -1.83 4.54E-02 NM_022807 SNRPN [NM 022807] -1.84 4.73E-02 NM_004416 DTX1 Homo sapiens deltex homolog 1 (Drosophila) (DTX1), mRNA [NM_004416] -1.85 4.26E-02 NM_181900 STARD5 Homo sapiens START domain containing 5 (STARD5), mRNA [NM_181900] Homo sapiens cDNA FLJ13629 fis, clone PLACE1011056, weakly similar to HISTONE H1, GONADAL. -1.85 2.75E-02 AK023691 CCDC71 [AK023691] Homo sapiens solute carrier family 4, sodium bicarbonate cotransporter, member 7 (SLC4A7), mRNA -1.85 3.53E-02 NM_003615 SLC4A7 [NM 003615] -1.85 3.70E-02 NM_024522 FAM77C Homo sapiens family with sequence similarity 77, member C (FAM77C), mRNA [NM_024522] -1.85 4.38E-02 NM_014466 TEKT2 Homo sapiens tektin 2 (testicular) (TEKT2), mRNA [NM_014466] -1.86 1.10E-02 NM_020774 MIB1 Homo sapiens mindbomb homolog 1 (Drosophila) (MIB1), mRNA [NM_020774] -1.87 4.54E-02 NM_018264 TYW1 Homo sapiens tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) (TYW1), mRNA [NM_018264] Homo sapiens transient receptor potential cation channel, subfamily M, member 6 (TRPM6), mRNA -1.88 1.59E-02 NM_017662 TRPM6 [NM 017662] -1.89 1.52E-02 NM_031460 KCNK17 Homo sapiens potassium channel, subfamily K, member 17 (KCNK17), mRNA [NM_031460] -1.89 4.54E-02 NM_006506 RASA2 Homo sapiens RAS p21 protein 2 (RASA2), mRNA [NM_006506] -1.89 1.48E-02 NM_003557 PIP5K1A Homo sapiens phosphatidylinositol-4-phosphate 5-kinase, type I, alpha (PIP5K1A), mRNA [NM_003557]

-1.89 6.08E-03 NM_005269 GLI1 Homo sapiens glioma-associated oncogene homolog 1 (zinc finger protein) (GLI1), mRNA [NM_005269]

-1.93 1.87E-02 NM_004600 TROVE2 Homo sapiens TROVE domain family, member 2 (TROVE2), transcript variant 2, mRNA [NM_004600] -1.93 7.30E-03 NM_177965 C8orf37 Homo sapiens open reading frame 37 (C8orf37), mRNA [NM_177965] -1.94 1.68E-02 NM_024830 AYTL2 Homo sapiens acyltransferase like 2 (AYTL2), mRNA [NM_024830] -1.96 4.91E-03 NM_023938 C1orf116 Homo sapiens chromosome 1 open reading frame 116 (C1orf116), mRNA [NM_023938] Homo sapiens quaking homolog, KH domain RNA binding (mouse) (QKI), transcript variant 1, mRNA -1.97 1.01E-02 NM_006775 QKI [NM 006775] -1.97 3.03E-03 NM_014985 CEP152 Homo sapiens centrosomal protein 152kDa (CEP152), mRNA [NM_014985] -1.98 5.06E-03 NM_182515 ZNF714 Homo sapiens zinc finger protein 714 (ZNF714), mRNA [NM_182515] -1.98 2.38E-02 NM_152730 C6orf170 Homo sapiens chromosome 6 open reading frame 170 (C6orf170), mRNA [NM_152730] PREDICTED: Homo sapiens similar to Nucleosome assembly protein 1-like 4 (Nucleosome assembly -1.99 9.78E-03 XR_015863 LOC731333 protein 2) (NAP2) (LOC731333), mRNA [XR 015863] -1.99 3.63E-02 NM_020193 C11orf30 Homo sapiens open reading frame 30 (C11orf30), mRNA [NM_020193] Homo sapiens sarcoglycan, gamma (35kDa dystrophin-associated ) (SGCG), mRNA -2.00 4.67E-02 NM_000231 SGCG [NM 000231] -2.02 3.16E-03 AK026372 AK026372 Homo sapiens cDNA: FLJ22719 fis, clone HSI14307. [AK026372] -2.05 3.76E-02 NM_001005526 SF3B1 Homo sapiens splicing factor 3b, subunit 1, 155kDa (SF3B1), transcript variant 2, mRNA [NM_001005526] Homo sapiens 1, regulatory (inhibitor) subunit 1B ( and cAMP regulated -2.06 4.51E-02 NM_032192 PPP1R1B phosphoprotein, DARPP-32) (PPP1R1B), transcript variant 1, mRNA [NM 032192] -2.06 2.50E-02 NM_181705 LYRM7 Homo sapiens Lyrm7 homolog (mouse) (LYRM7), mRNA [NM_181705] -2.07 4.51E-02 NM_031444 C22orf13 Homo sapiens open reading frame 13 (C22orf13), mRNA [NM_031444] Homo sapiens chromosome 20 open reading frame 132 (C20orf132), transcript variant 1, mRNA -2.07 1.22E-02 NM_152503 C20orf132 [NM 152503] -2.07 9.32E-03 NM_138281 DLX4 Homo sapiens distal-less homeobox 4 (DLX4), transcript variant 1, mRNA [NM_138281] Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F (APOBEC3F), -2.08 4.04E-02 NM_145298 APOBEC3F transcript variant 1, mRNA [NM 145298] -2.08 4.23E-02 AK124702 AK124702 Homo sapiens cDNA FLJ42712 fis, clone BRAMY3008044. [AK124702] -2.09 2.23E-02 NM_000704 ATP4A Homo sapiens ATPase, H+/K+ exchanging, alpha polypeptide (ATP4A), mRNA [NM_000704] -2.10 3.93E-02 NM_015310 PSD3 Homo sapiens pleckstrin and Sec7 domain containing 3 (PSD3), transcript variant 1, mRNA [NM_015310] -2.12 3.67E-02 NM_033647 HELB Homo sapiens helicase (DNA) B (HELB), mRNA [NM_033647] Homo sapiens low density lipoprotein receptor-related protein 8, apolipoprotein e receptor (LRP8), -2.15 5.00E-02 NM_033300 LRP8 transcript variant 2, mRNA [NM 033300] Homo sapiens cDNA: FLJ21682 fis, clone COL09332, highly similar to AF169548 Homo sapiens gamma- -2.17 3.56E-02 AK025335 AP1GBP1 synergin mRNA. [AK025335] -2.17 3.71E-03 NM_024908 WDR76 Homo sapiens WD repeat domain 76 (WDR76), mRNA [NM_024908] -2.18 2.97E-02 NM_020774 MIB1 Homo sapiens mindbomb homolog 1 (Drosophila) (MIB1), mRNA [NM_020774] AGENCOURT_7776008 NIH_MGC_68 Homo sapiens cDNA clone IMAGE:6024246 5', mRNA sequence -2.21 2.31E-02 BQ439266 BQ439266 [BQ439266] Homo sapiens ATPase, Na+/K+ transporting, beta 1 polypeptide (ATP1B1), transcript variant 1, mRNA -2.23 8.20E-03 NM_001677 ATP1B1 [NM 001677] -2.23 1.48E-02 NM_003965 CCRL2 Homo sapiens chemokine (C-C motif) receptor-like 2 (CCRL2), mRNA [NM_003965] -2.39 4.24E-02 NM_017520 HSMPP8 Homo sapiens M-phase phosphoprotein, mpp8 (HSMPP8), mRNA [NM_017520] -2.46 4.61E-02 AB032969 KIAA1143 Homo sapiens mRNA for KIAA1143 protein, partial cds. [AB032969] 601452004F1 NIH_MGC_66 Homo sapiens cDNA clone IMAGE:3855793 5', mRNA sequence -2.53 2.13E-02 BE612504 BE612504 [BE612504] -2.53 6.72E-03 NM_002738 PRKCB1 Homo sapiens protein kinase C, beta 1 (PRKCB1), transcript variant 2, mRNA [NM_002738] -2.54 3.18E-02 NM_018561 USP49 Homo sapiens ubiquitin specific peptidase 49 (USP49), mRNA [NM_018561] Homo sapiens calcitonin gene-related -receptor component protein (RCP9), transcript variant 1, -2.63 4.36E-02 NM_014478 RCP9 mRNA [NM 014478] -3.08 2.29E-02 NM_032932 RAB11FIP4 Homo sapiens RAB11 family interacting protein 4 (class II) (RAB11FIP4), mRNA [NM_032932] Table S2. Ingenuity Pathway Analysis: Canonical Pathways, 4 vs. 0 Gy irradiation

No overlap -Log(P -value) Ratio Downregulated No change Upregulated Molecules Canonical Pathways with dataset IGFBP6, CDKN1A, CSNK2A1, VDR/RXR Activation 2.97E00 7.5E-02 4/80 (5%) 0/80 (0%) 2/80 (3%) 74/80 (93%) HES1, RXRB, PRKCB TP53INP1, CDKN1A, p53 Signaling 2.69E00 6.74E-02 0/89 (0%) 0/89 (0%) 6/89 (7%) 83/89 (93%) TNFRSF10B, C12ORF5, MDM2, HIPK2 TFF1, NQO1, CDKN1A, MDM2, Aryl Hydrocarbon Receptor Signaling 2.32E00 4.46E-02 2/157 (1%) 0/157 (0%) 5/157 (3%) 150/157 (96%) DHFR, RXRB, AHR TNFRSF10B, TNFRSF10C, Mediated Signaling 1.88E00 6.82E-02 1/44 (2%) 0/44 (0%) 2/44 (5%) 41/44 (93%) RXRB Hypoxia Signaling in the Cardiovascular NQO1, MDM2, CREB3L4, 1.85E00 5.71E-02 1/70 (1%) 0/70 (0%) 3/70 (4%) 66/70 (94%) System UBE2S CRCP, RP2, APOBEC3F, DPYD, Pyrimidine 1.81E00 2.59E-02 3/232 (1%) 0/232 (0%) 3/232 (1%) 226/232 (97%) POLH, POLE3 ATM Signaling 1.38E00 5.77E-02 1/52 (2%) 0/52 (0%) 2/52 (4%) 49/52 (94%) CDKN1A, MDM2, CREB3L4 Fcγ Receptor-mediated Phagocytosis in PIP5K1A, INPP5D, VASP, 1.32E00 3.85E-02 2/104 (2%) 0/104 (0%) 2/104 (2%) 100/104 (96%) Macrophages and Monocytes PRKCB MYO6, DNM1, AMPH, Clathrin-mediated Endocytosis Signaling 1.13E00 2.99E-02 3/167 (2%) 0/167 (0%) 2/167 (1%) 162/167 (97%) CSNK2A1, MDM2 Interferon Signaling 1.13E00 6.67E-02 1/30 (3%) 0/30 (0%) 1/30 (3%) 28/30 (93%) IFIT3, PIAS1 Corticotropin Releasing Hormone Signaling 1.05E00 2.94E-02 3/136 (2%) 0/136 (0%) 1/136 (1%) 132/136 (97%) MEF2C, CREB3L4, GLI1, PDGF Signaling 1.04E00 3.8E-02 2/79 (3%) 0/79 (0%) 1/79 (1%) 76/79 (96%) CSNK2A1, INPP5D, PRKCB Notch Signaling 1.01E00 4.65E-02 2/43 (5%) 0/43 (0%) 0/43 (0%) 41/43 (95%) DTX1, HES1 B3GAT1, CSGALNACT1, Androgen and Estrogen Metabolism 1.01E00 2.1E-02 1/143 (1%) 0/143 (0%) 2/143 (1%) 140/143 (98%) SULF2 : G2/M DNA Damage Checkpoint 9.32E-01 4.65E-02 0/43 (0%) 0/43 (0%) 2/43 (5%) 41/43 (95%) CDKN1A, MDM2 Regulation Cancer Signaling 9.19E-01 3.12E-02 1/96 (1%) 0/96 (0%) 2/96 (2%) 93/96 (97%) CDKN1A, MDM2, CREB3L4 Allograft Rejection Signaling 9.13E-01 4.44E-02 1/45 (2%) 0/45 (0%) 1/45 (2%) 43/45 (96%) CD40, FAS PIP5K1A, INPP5B, ITPKA, Inositol Phosphate Metabolism 8.9E-01 2.84E-02 3/176 (2%) 0/176 (0%) 2/176 (1%) 171/176 (97%) PIP4K2C, INPP5D TR/RXR Activation 8.84E-01 3.19E-02 1/94 (1%) 0/94 (0%) 2/94 (2%) 91/94 (97%) HP, MDM2, RXRB HHAT, RALA, CDKN1A, Molecular Mechanisms of Cancer 8.84E-01 2.15E-02 2/372 (1%) 0/372 (0%) 6/372 (2%) 364/372 (98%) MDM2, HIPK2, GLI1, FAS, PRKCB Melanoma Signaling 8.79E-01 4.35E-02 0/46 (0%) 0/46 (0%) 2/46 (4%) 44/46 (96%) CDKN1A, MDM2 Autoimmune Disease Signaling 8.79E-01 4.26E-02 1/47 (2%) 0/47 (0%) 1/47 (2%) 45/47 (96%) CD40, FAS Metabolism 8.79E-01 3.08E-02 1/65 (2%) 0/65 (0%) 1/65 (2%) 63/65 (97%) B3GAT1, CSGALNACT1 CRCP, PRPS2, RP2, ATP1B1, Purine Metabolism 8.79E-01 1.59E-02 5/440 (1%) 0/440 (0%) 2/440 (0%) 433/440 (98%) GMPS, POLH, POLE3 Crosstalk between Dendritic Cells and Natural 8.4E-01 3.06E-02 1/98 (1%) 0/98 (0%) 2/98 (2%) 95/98 (97%) CD40, TREM2, FAS Killer Cells Chondroitin Sulfate Biosynthesis 8.31E-01 2.99E-02 1/67 (1%) 0/67 (0%) 1/67 (1%) 65/67 (97%) B3GAT1, CSGALNACT1 PTEN Signaling 8.09E-01 2.86E-02 1/105 (1%) 0/105 (0%) 2/105 (2%) 102/105 (97%) CDKN1A, CSNK2A1, INPP5D Pentose and Glucuronate Interconversions 8.01E-01 1.32E-02 1/152 (1%) 0/152 (0%) 1/152 (1%) 150/152 (99%) B3GAT1, CSGALNACT1 p38 MAPK Signaling 7.9E-01 3.16E-02 1/95 (1%) 0/95 (0%) 2/95 (2%) 92/95 (97%) MEF2C, CREB3L4, FAS Glioma Signaling 7.61E-01 2.68E-02 1/112 (1%) 0/112 (0%) 2/112 (2%) 109/112 (97%) CDKN1A, MDM2, PRKCB Folate Biosynthesis 7.17E-01 1.25E-02 1/80 (1%) 0/80 (0%) 0/80 (0%) 79/80 (99%) DHFR Pancreatic Adenocarcinoma Signaling 7.07E-01 2.59E-02 0/116 (0%) 0/116 (0%) 3/116 (3%) 113/116 (97%) RALA, CDKN1A, MDM2 Natural Killer 6.91E-01 2.61E-02 1/115 (1%) 0/115 (0%) 2/115 (2%) 112/115 (97%) INPP5D, SIGLEC7, PRKCB Death Receptor Signaling 6.61E-01 3.12E-02 0/64 (0%) 0/64 (0%) 2/64 (3%) 62/64 (97%) TNFRSF10B, FAS 14-3-3-mediated Signaling 6.58E-01 2.63E-02 1/114 (1%) 0/114 (0%) 2/114 (2%) 111/114 (97%) TUBB3, TUBA1C, PRKCB Glyoxylate and Dicarboxylate Metabolism 6.42E-01 8.55E-03 1/117 (1%) 0/117 (0%) 0/117 (0%) 116/117 (99%) AFMID (includes EG:125061) JAK/Stat Signaling 6.29E-01 3.12E-02 1/64 (2%) 0/64 (0%) 1/64 (2%) 62/64 (97%) PIAS1, CDKN1A Pantothenate and CoA Biosynthesis 6.2E-01 1.56E-02 0/64 (0%) 0/64 (0%) 1/64 (2%) 63/64 (98%) DPYD GM-CSF Signaling 6.19E-01 2.99E-02 1/67 (1%) 0/67 (0%) 1/67 (1%) 65/67 (97%) RUNX1, PRKCB ERK5 Signaling 6.09E-01 2.9E-02 1/69 (1%) 0/69 (0%) 1/69 (1%) 67/69 (97%) MEF2C, CREB3L4 PI3K/AKT Signaling 6.06E-01 2.21E-02 0/136 (0%) 0/136 (0%) 3/136 (2%) 133/136 (98%) CDKN1A, MDM2, INPP5D Lipid Antigen Presentation by CD1 6E-01 4.55E-02 0/22 (0%) 0/22 (0%) 1/22 (5%) 21/22 (95%) CALR One Carbon Pool by Folate 5.81E-01 2.56E-02 1/39 (3%) 0/39 (0%) 0/39 (0%) 38/39 (97%) DHFR CCR5 Signaling in Macrophages 5.71E-01 2.2E-02 1/91 (1%) 0/91 (0%) 1/91 (1%) 89/91 (98%) FAS, PRKCB FLT3 Signaling in Hematopoietic Progenitor 5.62E-01 2.74E-02 1/73 (1%) 0/73 (0%) 1/73 (1%) 71/73 (97%) CREB3L4, INPP5D Cells GNRH Signaling 5.46E-01 2.1E-02 3/143 (2%) 0/143 (0%) 0/143 (0%) 140/143 (98%) DNM1, CREB3L4, PRKCB IL-3 Signaling 5.44E-01 2.74E-02 1/73 (1%) 0/73 (0%) 1/73 (1%) 71/73 (97%) INPP5D, PRKCB Cytotoxic T -mediated Apoptosis of 4.85E-01 3.23E-02 0/31 (0%) 0/31 (0%) 1/31 (3%) 30/31 (97%) FAS Target Cells Biosynthesis of Steroids 4.85E-01 7.81E-03 0/128 (0%) 0/128 (0%) 1/128 (1%) 127/128 (99%) NQO1 Aldosterone Signaling in Epithelial Cells 4.74E-01 3.06E-02 2/98 (2%) 0/98 (0%) 1/98 (1%) 95/98 (97%) PIP5K1A, PIP4K2C, PRKCB Factors Promoting Cardiogenesis in Vertebrates 4.67E-01 2.25E-02 1/89 (1%) 0/89 (0%) 1/89 (1%) 87/89 (98%) MEF2C, PRKCB Sonic Hedgehog Signaling 4.59E-01 3.23E-02 1/31 (3%) 0/31 (0%) 0/31 (0%) 30/31 (97%) GLI1 NF-κB Signaling 4.55E-01 2.01E-02 3/149 (2%) 0/149 (0%) 0/149 (0%) 146/149 (98%) CD40, CSNK2A1, PRKCB Urea Cycle and Metabolism of Amino Groups 4.47E-01 1.25E-02 1/80 (1%) 0/80 (0%) 0/80 (0%) 79/80 (99%) CKM Starch and Sucrose Metabolism 4.47E-01 1.01E-02 1/198 (1%) 0/198 (0%) 1/198 (1%) 196/198 (99%) B3GAT1, CSGALNACT1 Receptor Signaling 4.4E-01 1.94E-02 2/155 (1%) 0/155 (0%) 1/155 (1%) 152/155 (98%) CREB3L4, INPP5D, PRKCB Pentose Phosphate Pathway 4.36E-01 1.11E-02 1/90 (1%) 0/90 (0%) 0/90 (0%) 89/90 (99%) PRPS2 DNM1, CREB3L4, UBE2S, Huntington's Disease Signaling 4.34E-01 1.69E-02 3/236 (1%) 0/236 (0%) 1/236 (0%) 232/236 (98%) PRKCB Virus Entry via Endocytic Pathways 4.34E-01 2.08E-02 2/96 (2%) 0/96 (0%) 0/96 (0%) 94/96 (98%) DNM1, PRKCB Bladder Cancer Signaling 4.27E-01 2.15E-02 0/93 (0%) 0/93 (0%) 2/93 (2%) 91/93 (98%) CDKN1A, MDM2 Circadian Rhythm Signaling 4.24E-01 2.86E-02 1/35 (3%) 0/35 (0%) 0/35 (0%) 34/35 (97%) CREB3L4 IGF-1 Signaling 4.15E-01 2.04E-02 1/98 (1%) 0/98 (0%) 1/98 (1%) 96/98 (98%) IGFBP6, CSNK2A1 Role of CHK in Cell Cycle Checkpoint 4.03E-01 2.94E-02 0/34 (0%) 0/34 (0%) 1/34 (3%) 33/34 (97%) CDKN1A Control Antigen Presentation Pathway 4.03E-01 2.56E-02 0/39 (0%) 0/39 (0%) 1/39 (3%) 38/39 (97%) CALR Dendritic Cell Maturation 3.94E-01 1.73E-02 2/173 (1%) 0/173 (0%) 1/173 (1%) 170/173 (98%) CD40, CREB3L4, TREM2 CSNK2A1, MDM2, SOX5 Wnt/β-catenin Signaling 3.94E-01 1.82E-02 2/165 (1%) 0/165 (0%) 1/165 (1%) 162/165 (98%) (includes EG:6660) Glycosaminoglycan Degradation 3.93E-01 1.39E-02 0/72 (0%) 0/72 (0%) 1/72 (1%) 71/72 (99%) SULF2 Glutamate Metabolism 3.93E-01 1.28E-02 1/78 (1%) 0/78 (0%) 0/78 (0%) 77/78 (99%) GMPS Chronic Myeloid Leukemia Signaling 3.8E-01 1.9E-02 0/105 (0%) 0/105 (0%) 2/105 (2%) 103/105 (98%) CDKN1A, MDM2 Fc Epsilon RI Signaling 3.7E-01 1.9E-02 1/105 (1%) 0/105 (0%) 1/105 (1%) 103/105 (98%) INPP5D, PRKCB RAR Activation 3.64E-01 1.69E-02 3/178 (2%) 0/178 (0%) 0/178 (0%) 175/178 (98%) CSNK2A1, RXRB, PRKCB HGF Signaling 3.59E-01 1.92E-02 1/104 (1%) 0/104 (0%) 1/104 (1%) 102/104 (98%) CDKN1A, PRKCB Cholecystokinin/Gastrin-mediated Signaling 3.59E-01 1.92E-02 1/104 (1%) 0/104 (0%) 1/104 (1%) 102/104 (98%) MEF2C, PRKCB FcγRIIB Signaling in B 3.57E-01 1.79E-02 0/56 (0%) 0/56 (0%) 1/56 (2%) 55/56 (98%) INPP5D Mechanisms of Viral Exit from Host Cells 3.57E-01 2.27E-02 1/44 (2%) 0/44 (0%) 0/44 (0%) 43/44 (98%) PRKCB Thyroid Cancer Signaling 3.57E-01 2.22E-02 1/45 (2%) 0/45 (0%) 0/45 (0%) 44/45 (98%) RXRB iCOS-iCOSL Signaling in T Helper Cells 3.54E-01 1.74E-02 1/115 (1%) 0/115 (0%) 1/115 (1%) 113/115 (98%) CD40, INPP5D T Helper Cell Differentiation 3.49E-01 2.44E-02 1/41 (2%) 0/41 (0%) 0/41 (0%) 40/41 (98%) CD40 Type I Diabetes Mellitus Signaling 3.35E-01 1.75E-02 1/114 (1%) 0/114 (0%) 1/114 (1%) 112/114 (98%) PIAS1, FAS Graft-versus-Host Disease Signaling 3.33E-01 2.22E-02 0/45 (0%) 0/45 (0%) 1/45 (2%) 44/45 (98%) FAS Calcium Signaling 3.23E-01 1.46E-02 1/206 (0%) 0/206 (0%) 2/206 (1%) 203/206 (99%) CALR, MEF2C, CREB3L4 Histidine Metabolism 3.18E-01 8.33E-03 1/120 (1%) 0/120 (0%) 0/120 (0%) 119/120 (99%) PRPS2 Synaptic Long Term Potentiation 3.16E-01 1.74E-02 2/115 (2%) 0/115 (0%) 0/115 (0%) 113/115 (98%) CREB3L4, PRKCB IL-12 Signaling and Production in 3.16E-01 1.52E-02 2/132 (2%) 0/132 (0%) 0/132 (0%) 130/132 (98%) CD40, PRKCB Macrophages Role of Oct4 in Mammalian Embryonic Stem 3.04E-01 2.22E-02 1/45 (2%) 0/45 (0%) 0/45 (0%) 44/45 (98%) RXRB Cell Pluripotency GABA Receptor Signaling 3.04E-01 1.82E-02 1/55 (2%) 0/55 (0%) 0/55 (0%) 54/55 (98%) DNM1 EGF Signaling 2.98E-01 1.92E-02 1/52 (2%) 0/52 (0%) 0/52 (0%) 51/52 (98%) CSNK2A1 CDKN1A, PBX1, TAF3, Signaling 2.97E-01 1.43E-02 1/280 (0%) 0/280 (0%) 3/280 (1%) 276/280 (99%) CDKN1C Androgen Signaling 2.91E-01 1.38E-02 1/145 (1%) 0/145 (0%) 1/145 (1%) 143/145 (99%) CALR, PRKCB Role of BRCA1 in DNA Damage Response 2.73E-01 1.89E-02 0/53 (0%) 0/53 (0%) 1/53 (2%) 52/53 (98%) CDKN1A Amyloid Processing 2.73E-01 1.79E-02 1/56 (2%) 0/56 (0%) 0/56 (0%) 55/56 (98%) CSNK2A1 Integrin Signaling 2.71E-01 1.48E-02 1/203 (0%) 0/203 (0%) 2/203 (1%) 200/203 (99%) ARF1, RALA, VASP IL-2 Signaling 2.56E-01 1.72E-02 1/58 (2%) 0/58 (0%) 0/58 (0%) 57/58 (98%) CSNK2A1 β- Metabolism 2.56E-01 1.02E-02 0/98 (0%) 0/98 (0%) 1/98 (1%) 97/98 (99%) DPYD Thrombopoietin Signaling 2.51E-01 1.61E-02 1/62 (2%) 0/62 (0%) 0/62 (0%) 61/62 (98%) PRKCB Hepatic Fibrosis / Hepatic Stellate Cell 2.47E-01 1.48E-02 1/135 (1%) 0/135 (0%) 1/135 (1%) 133/135 (99%) CD40, FAS Activation TREM1 Signaling 2.46E-01 1.45E-02 1/69 (1%) 0/69 (0%) 0/69 (0%) 68/69 (99%) CD40 Mediated Apoptosis Signaling 2.41E-01 1.67E-02 0/60 (0%) 0/60 (0%) 1/60 (2%) 59/60 (98%) FAS Cell Cycle: G1/S Checkpoint Regulation 2.41E-01 1.69E-02 0/59 (0%) 0/59 (0%) 1/59 (2%) 58/59 (98%) CDKN1A Metabolism of Xenobiotics by Cytochrome 2.37E-01 9.52E-03 1/210 (0%) 0/210 (0%) 1/210 (0%) 208/210 (99%) B3GAT1, CSGALNACT1 P450 Primary Immunodeficiency Signaling 2.36E-01 1.59E-02 1/63 (2%) 0/63 (0%) 0/63 (0%) 62/63 (98%) CD40 Calcium-induced T Lymphocyte Apoptosis 2.31E-01 1.54E-02 1/65 (2%) 0/65 (0%) 0/65 (0%) 64/65 (98%) PRKCB Systemic Lupus Erythematosus Signaling 2.28E-01 1.33E-02 1/150 (1%) 0/150 (0%) 1/150 (1%) 148/150 (99%) CD40, INPP5D Induction of Apoptosis by HIV1 2.27E-01 1.54E-02 0/65 (0%) 0/65 (0%) 1/65 (2%) 64/65 (98%) FAS Aminosugars Metabolism 2.22E-01 8.2E-03 0/122 (0%) 0/122 (0%) 1/122 (1%) 121/122 (99%) NQO1 Ubiquinone Biosynthesis 2.22E-01 8.4E-03 0/119 (0%) 0/119 (0%) 1/119 (1%) 118/119 (99%) NDUFB2 CD40 Signaling 2.14E-01 1.45E-02 1/69 (1%) 0/69 (0%) 0/69 (0%) 68/69 (99%) CD40 Basal Cell Carcinoma Signaling 2.14E-01 1.47E-02 1/68 (1%) 0/68 (0%) 0/68 (0%) 67/68 (99%) GLI1 Activation of IRF by Cytosolic Pattern 2.09E-01 1.37E-02 1/73 (1%) 0/73 (0%) 0/73 (0%) 72/73 (99%) CD40 Recognition Receptors Glycine, Serine and Threonine Metabolism 2.09E-01 6.67E-03 1/150 (1%) 0/150 (0%) 0/150 (0%) 149/150 (99%) GLDC IL-4 Signaling 2.05E-01 1.39E-02 0/72 (0%) 0/72 (0%) 1/72 (1%) 71/72 (99%) INPP5D Macropinocytosis Signaling 2.05E-01 1.39E-02 1/72 (1%) 0/72 (0%) 0/72 (0%) 71/72 (99%) PRKCB Erythropoietin Signaling 2.01E-01 1.32E-02 1/76 (1%) 0/76 (0%) 0/76 (0%) 75/76 (99%) PRKCB Non-Small Cell Cancer Signaling 2.01E-01 1.27E-02 1/79 (1%) 0/79 (0%) 0/79 (0%) 78/79 (99%) RXRB Neurotrophin/TRK Signaling 2.01E-01 1.28E-02 1/78 (1%) 0/78 (0%) 0/78 (0%) 77/78 (99%) CREB3L4 Growth Hormone Signaling 1.97E-01 1.37E-02 1/73 (1%) 0/73 (0%) 0/73 (0%) 72/73 (99%) PRKCB Table S3. Ingenuity Pathway Analysis: Functions, 4 vs. 0 Gy irradiation Functions P -value Molecules

DPYD, PLK3, PBX1, EIF4A2, ATP4A, HES1, DDB2, LATS2, TTC22, FHL2, TFF1, MPHOSPH8, NEK6, CSNK2A1, TNFRSF10C, CBFB, TUBA1C, TTC5, HIPK2, CDKN1C, AHR, MYO6, IGFBP6, IFIT3, TUBB3, TP53INP1, NKTR, PPP1R1B, TNFRSF10B, L1CAM, UBE2S, RASD1, CD40, MIB1, LRP8, RUNX1, DHFR, HELB, Cancer 5.82E-06-3E-02 EBI3, RPL13A, KIAA1370, POLE3, FBXL7, PIAS1, GDF15, FAS, STK17A, GBP2, RXRB, VASP, CALR, ATP1B1, CKM, NQO1, TOB1, MDM2, SLC7A8, FDXR, INPP5D, DNM1, TRPM6, HP, GMPS, CDKN1A, MEF2C, GLI1, COBLL1, POLH, PRKCB

QKI, PLK3, PBX1, DDB2, HES1, TREM2, LATS2, FHL2, BLOC1S2, TFF1, MTF1, NEK6, CSNK2A1, CBFB, TTC5, TNFRSF10C, CDKN1C, HIPK2, AHR, MYO6, SHISA5, IGFBP6, TUBB3, TP53INP1, SGCG, PPP1R1B, TNFRSF10B, L1CAM, Cell Death 5.82E-06-2.66E-02 UBE2S, LAX1, RASD1, NCF1, MNT, CD40, MIB1, RUNX1, GDF15, PIAS1, FAS, STK17A, RPS3, SOX5 (includes EG:6660), CALR, THG1L, NQO1, CDC42EP3, MDM2, INPP5D, FDXR, DNM1, CDKN1A, MEF2C, GLI1, PRKCB, POLH IGFBP6, TUBB3, PIAS1, NQO1, TNFRSF10B, MDM2, DDB2, INPP5D, RASD1, Respiratory Disease 5.82E-06-2.86E-02 FAS, FDXR, NEK6, CDKN1A, TUBA1C, DHFR, RXRB, CDKN1C, HIPK2, AHR, POLE3, PRKCB, POLH CRCP, PIAS1, PBX1, DLX4, NR1D2, HES1, DDB2, FAS, TEAD1, DTX1, FHL2, TFF1, MTF1, AMPH, NEK6, ZNF808, TAF3, TTC5, CBFB, CDKN1C, RXRB, 1.68E-04-2.66E-02 HIPK2, VASP, AHR, SOX5 (includes EG:6660), MYO6, CALR, PPP1R1B, STARD5, TNFRSF10B, MDM2, L1CAM, CREB3L4, INPP5D, HP, MNT, CD40, CDKN1A, MEF2C, HELB, RUNX1, TROVE2, GLI1, PRKCB, SSB RALA, PLK3, GDF15, ATP4A, HES1, LATS2, FAS, ANK1, MACF1, CSNK2A1, Cell Morphology 2.19E-04-1.87E-02 CBFB, CDKN1C, RXRB, VASP, AHR, PRICKLE2, TNFRSF10B, MDM2, L1CAM, DNM1, PIP5K1A, CD40, MIB1, CDKN1A, FOXJ1, B3GAT1, LRP8, NDST2, GLI1

RALA, TUBGCP3, NQO1, TNFRSF10B, PLEC1, MDM2, FAS, ANK1, DNM1, Cellular Assembly and Organization 2.27E-04-3E-02 TUBGCP5, RAB11FIP4, AMPH, CDKN1A, TTL, NDST2, CDKN1C, VASP, AHR

CTSK, RP2, SGCG, NQO1, PBX1, SLC17A5, ATP4A, MDM2, HES1, INPP5D, Developmental Disorder 2.27E-04-2.41E-02 FBXW8, SNRPN, NCF1, TEAD1, FHL2, MNT, CDKN1A, DHFR, HIPK2, CDKN1C, AHR, PRKCB Endocrine System Disorders 2.27E-04-1.51E-02 TP53INP1, PBX1, L1CAM, MDM2, HES1, GLI1, AHR Morphology 2.27E-04-2.69E-02 MNT, CDKN1A, PBX1, ELOVL3, HES1, INPP5D, AHR

EFR3A, DPYD, NRXN3, PLK3, PBX1, EIF4A2, ATP4A, HES1, LATS2, ANK1, SNRPN, TUBGCP5, TFF1, TUBA1C, CDKN1C, HIPK2, AHR, MYO6, TP53INP1, TUBB3, PPP1R1B, TNFRSF10B, SLC4A7, L1CAM, NCF1, CD40, LRP8, NPLOC4, Gastrointestinal Disease 2.29E-04-2.69E-02 RUNX1, DHFR, EBI3, RPL13A, POLE3, KIAA1370, TMTC3, GDF15, PDDC1, C6ORF170, FAS, TEAD1, SP140, DNAH5, KIAA1267, SULF2, SOX5 (includes EG:6660), ATP1B1, PCMTD2, ATG10, DNER, NQO1, CSGALNACT1, LOXL3, INPP5D, FDXR, AKD1, HP, GMPS, CDKN1A, COL24A1, COBLL1, PRKCB, POLH

TP53INP1, PIAS1, TNFRSF10B, PBX1, L1CAM, HES1, FAS, DNM1, MTF1, Embryonic Development 2.67E-04-1.66E-02 RUNX1, HIPK2, GLI1, VASP, AHR MYO6, CALR, IGFBP6, TUBB3, RALA, QKI, PPP1R1B, DNER, GDF15, PBX1, Development and Function 2.67E-04-2.66E-02 L1CAM, HES1, DNM1, PIP5K1A, DTX1, MIB1, CDKN1A, AMPH, TTL, RUNX1, CDKN1C, GLI1, VASP, AHR MYO6, CALR, SORL1, NQO1, MDM2, TREM2, LATS2, INPP5D, FAS, DNM1, Cellular Function and Maintenance 4.38E-04-2.83E-02 PIP5K1A, CD40, AMPH, CDKN1A, CSNK2A1, LRP8, TTC5, GBP2, RXRB, GLI1, PRKCB Hepatic System Disease 4.49E-04-2.69E-02 NCF1, MNT, CD40, CDKN1A, TNFRSF10B, CSNK2A1, HES1, HIPK2, FAS, AHR GDF15, ATP4A, DDB2, FAS, CCRL2, NEK6, TUBA1C, RXRB, HIPK2, AHR, Dermatological Diseases and Conditions 4.52E-04-2.96E-02 SIGLEC7, ZNF331, TUBB3, NQO1, PLEC1, MDM2, MNT, CD40, CDKN1A, RAPH1, COL24A1, DHFR, GLI1, POLH, PRKCB GDF15, PIAS1, PBX1, HES1, FAS, FHL2, HS6ST2, CBFB, CDKN1C, HIPK2, VASP, AHR, CALR, IGFBP6, TUBB3, TP53INP1, TNFRSF10B, TOB1, PTP4A1, Cellular Growth and Proliferation 4.8E-04-2.96E-02 MDM2, INPP5D, TRPM6, NCF1, MNT, CD40, CDKN1A, UHMK1, DHFR, RUNX1, GLI1, PRKCB PPP1R1B, TNFRSF10B, PLEC1, MDM2, L1CAM, HES1, LATS2, TREM2, LAX1, Cell-To-Cell Signaling and Interaction 6.74E-04-3E-02 INPP5D, FAS, CD40, FOXJ1, CDKN1A, TTC5, GBP2, GLI1 DPYD, QKI, NRXN3, PBX1, ATP4A, LATS2, ANK1, MYRIP, MTF1, AMPH, TNFRSF10C, TUBA1C, CDKN1C, AHR, TP53INP1, TUBB3, SORL1, TNFRSF10B, ATP10A, L1CAM, NCF1, PSD3, CD40, RAPH1, DHFR, RUNX1, KIAA1370, EAF1, Connective Tissue Disorders 6.74E-04-1.83E-02 FAS, TEAD1, SP140, KIAA0247, STK17A, DNAH5, TAF3, RPS3, SOX5 (includes EG:6660), STK19, KCNK17, DNER, MDM2, INPP5D, DNM1, ARF1, HP, ZNF714, CDKN1A, COL24A1, RAD51AP1, PRKCB CROT, QKI, FAR1, ELOVL3, INPP5D, FAS, PON1, PIP5K1A, ARF1, CD40, Lipid Metabolism 7.79E-04-3E-02 INPP5B, AHR, PRKCB, EEA1 CALR, CROT, CKM, NQO1, ELOVL3, INPP5D, FAS, PON1, PIP5K1A, ARF1, Molecular Transport 7.79E-04-3E-02 CD40, INPP5B, UHMK1, AHR, EEA1 CROT, DPYD, QKI, PPP1R1B, NQO1, FAR1, ELOVL3, DDB2, CSGALNACT1, Small Molecule 7.79E-04-3E-02 INPP5D, FAS, PON1, ARF1, PIP5K1A, GMPS, CD40, INPP5B, B3GAT1, NDST2, DHFR, AHR, PRKCB, POLH, EEA1 TUBB3, NQO1, TNFRSF10B, PBX1, MDM2, INPP5D, FAS, TRPM6, GMPS, CD40, Hematological Disease 8.3E-04-3E-02 CDKN1A, CBFB, TUBA1C, RUNX1, DHFR, RXRB, VASP, POLE3, PRKCB CALR, TP53INP1, GDF15, PIAS1, MDM2, HES1, LATS2, INPP5D, FAS, DNM1, Cell Cycle 8.69E-04-3E-02 SESN1, MNT, CD40, CDKN1A, NEK6, CSNK2A1, UHMK1, RUNX1, CDKN1C, HIPK2, AHR QKI, PBX1, HES1, TREM2, FAS, ANK1, FOXN4, FHL2, DTX1, TFF1, CBFB, CDKN1C, RXRB, AHR, VASP, SOX5 (includes EG:6660), MYO6, IGFBP6, CALR, Cellular Development 8.69E-04-2.96E-02 CTSK, TUBB3, PPP1R1B, DNER, TNFRSF10B, TOB1, L1CAM, MDM2, INPP5D, NCF1, MNT, CD40, MIB1, CDKN1A, MEF2C, RUNX1, GLI1, PRKCB

CALR, TUBB3, TNFRSF10B, GDF15, PBX1, L1CAM, MDM2, DDB2, HES1, Reproductive System Disease 1.09E-03-2.48E-02 LATS2, FAS, DNM1, TFF1, MIB1, CDKN1A, CSNK2A1, TUBA1C, MEF2C, TTC5, DHFR, AHR, POLE3 TP53INP1, TNFRSF10B, GDF15, PBX1, MDM2, HES1, TREM2, LAX1, FAS, Hematological System Development and 1.23E-03-2.66E-02 INPP5D, MNT, CD40, FOXJ1, CDKN1A, CBFB, RUNX1, CDKN1C, EBI3, AHR, Function PRKCB CD40, TNFRSF10B, GDF15, PBX1, L1CAM, CBFB, HES1, RUNX1, CDKN1C, Hematopoiesis 1.23E-03-2.96E-02 INPP5D, FAS Hair and Skin Development and Function 1.34E-03-1.51E-02 DNM1, TP53INP1, L1CAM, ELOVL3, HIPK2 TP53INP1, CKM, NQO1, L1CAM, CSGALNACT1, INPP5D, FAS, PON1, PIP5K1A, Carbohydrate Metabolism 1.41E-03-2.37E-02 ARF1, CD40, INPP5B, B3GAT1, NDST2, PRKCB

EFR3A, DPYD, NRXN3, PBX1, EIF4A2, ATP4A, DDB2, LATS2, ANK1, PON1, SNRPN, TUBGCP5, CCDC50, MYRIP, TFF1, AMPH, NEK6, CBFB, KIAA1704, TNFRSF10C, TUBA1C, CDKN1C, HIPK2, AHR, MYO6, TUBB3, TP53INP1, SORL1, PRICKLE2, TNFRSF10B, PLEC1, SLC4A7, L1CAM, ATP10A, NCF1, PSD3, CD40, LRP8, NPLOC4, RUNX1, DHFR, TROVE2, EBI3, KIAA1370, POLE3, Genetic Disorder 1.42E-03-2.96E-02 TMTC3, GDF15, PDDC1, EAF1, C6ORF170, FAS, MACF1, TEAD1, SP140, KIAA0247, DNAH5, KIAA1267, TAF3, KIAA1109, TULP4, RPS3, SULF2, RXRB, SOX5 (includes EG:6660), STK19, CTSK, KCNK17, ATP1B1, PCMTD2, DNER, NQO1, MDM2, CSGALNACT1, LOXL3, FDXR, INPP5D, AKD1, DNM1, TRPM6, HP, ARF1, GMPS, ZNF714, CDKN1A, COL24A1, RAD51AP1, POLH, PRKCB

EFR3A, DPYD, NRXN3, PBX1, ATP4A, LATS2, ANK1, SNRPN, TUBGCP5, MYRIP, AMPH, TUBA1C, TNFRSF10C, AHR, ZNF331, TP53INP1, TUBB3, SORL1, TNFRSF10B, SLC4A7, L1CAM, ATP10A, NCF1, PSD3, MNT, CD40, RAPH1, NPLOC4, RUNX1, DHFR, EBI3, POLE3, KIAA1370, TMTC3, PDDC1, Inflammatory Disease 1.42E-03-2.66E-02 EAF1, C6ORF170, FAS, TEAD1, SP140, KIAA0247, DNAH5, KIAA1267, TAF3, RXRB, RPS3, SULF2, SOX5 (includes EG:6660), STK19, KCNK17, ATP1B1, PCMTD2, DNER, MDM2, CSGALNACT1, LOXL3, INPP5D, AKD1, DNM1, HP, ARF1, ZNF714, FOXJ1, CDKN1A, COL24A1, RAD51AP1, PRKCB

DPYD, NRXN3, PBX1, EIF4A2, ATP4A, DDB2, LATS2, ANK1, PON1, FHL2, MYRIP, AMPH, TNFRSF10C, TUBA1C, TTC5, CDKN1C, AHR, TUBB3, SORL1, SGCG, PPP1R1B, TNFRSF10B, PLEC1, L1CAM, ATP10A, NCF1, PSD3, CD40, MIB1, ANKRD11, RAPH1, NPLOC4, DHFR, RUNX1, RPL13A, NDUFB2, Skeletal and Muscular Disorders 1.46E-03-3E-02 KIAA1370, PIAS1, ISCU, EAF1, TYW1, FAS, MACF1, TEAD1, HHAT, SP140, KIAA0247, DNAH5, HS6ST2, TAF3, RPS3, SOX5 (includes EG:6660), STK19, CTSK, KCNK17, DNER, MDM2, INPP5D, DNM1, ARF1, HP, ZNF714, RAB11FIP4, CDKN1A, COL24A1, GLI1, RAD51AP1, PRKCB Cell Signaling 2.2E-03-1.33E-02 CALR, HHAT, CKM, HIPK2, GLI1 Cellular Compromise 2.2E-03-1.51E-02 RAB11FIP4, PLEC1, LATS2, FAS Cellular Movement 2.2E-03-1.51E-02 DNM1, TFF1, CD40, AMPH, GDF15, L1CAM MYO6, CALR, TUBB3, TNFRSF10B, L1CAM, FAS, CCDC50, NEK6, CDKN1A, Neurological Disease 2.2E-03-2.66E-02 TUBA1C, RUNX1, DHFR, HIPK2, CDKN1C, GLI1, POLE3, PRKCB Renal and Urological System Development and 2.2E-03-2.38E-02 DNM1, TP53INP1, PIAS1, TNFRSF10B, PTP4A1, L1CAM, HIPK2, INPP5D, FAS Function Vitamin and Mineral Metabolism 2.2E-03-1.51E-02 CALR, CKM, DHFR, AHR

DPYD, NRXN3, PBX1, ATP4A, LATS2, ANK1, PON1, SNRPN, MYRIP, NEK6, AMPH, TNFRSF10C, KIAA1704, TUBA1C, AHR, ZNF331, TUBB3, SORL1, PRICKLE2, TNFRSF10B, ATP10A, L1CAM, CLN5, NCF1, MNT, PSD3, CD40, LRP8, RUNX1, DHFR, TROVE2, KIAA1370, C6ORF170, EAF1, FAS, TEAD1, Immunological Disease 2.54E-03-2.66E-02 MACF1, SP140, KIAA0247, DNAH5, TAF3, TULP4, KIAA1109, RXRB, RPS3, VASP, SOX5 (includes EG:6660), CALR, STK19, KCNK17, DNER, MDM2, INPP5D, DNM1, TRPM6, HP, ARF1, ZNF714, FOXJ1, CDKN1A, COL24A1, RAD51AP1, PRKCB

MYO6, CALR, C4ORF16, MDM2, DDB2, RPS27L (includes EG:51065), LATS2, DNA Replication, Recombination, and Repair 3.27E-03-2.14E-02 FAS, SESN1, CD40, CDKN1A, HELB, HIPK2, GLI1, AHR, POLH, POLE3

Nucleic Acid Metabolism 3.27E-03-1.51E-02 DPYD, GMPS, CD40, NQO1, FAR1, DDB2, CSGALNACT1, FAS, POLH

Skeletal and Muscular System Development 3.7E-03-3E-02 CTSK, FHL2, CDKN1A, PLEC1, MEF2C, CBFB, RUNX1, CDKN1C, GLI1, ANK1 and Function TNFRSF10B, PIAS1, PBX1, TOB1, MDM2, LATS2, FAS, INPP5D, MNT, CD40, Connective Tissue Development and Function 4.52E-03-3E-02 CDKN1A, HS6ST2, HIPK2, AHR Reproductive System Development and 4.54E-03-2.37E-02 PBX1, HES1, GLI1, AHR Function Tissue Development 4.54E-03-1.51E-02 L1CAM, MEF2C, RUNX1, HES1, GLI1 PON1, CROT, DPYD, CD40, CDKN1A, NQO1, PBX1, ATP4A, RUNX1, DDB2, Organismal Development 4.61E-03-7.62E-03 FAS, PRKCB CALR, TNFRSF10B, TREM2, INPP5D, FAS, NCF1, HP, APOBEC3F, SP140, TFF1, Antigen Presentation 5.03E-03-2.76E-02 CD40, AMPH, EBI3, PRKCB Immune Cell Trafficking 5.03E-03-1.51E-02 CD40, FOXJ1, TNFRSF10B, TREM2, LAX1, FAS, INPP5D CALR, TP53INP1, MDM2, TREM2, LAX1, INPP5D, FAS, NCF1, HP, APOBEC3F, Humoral Immune Response 5.19E-03-2.76E-02 CD40, SP140, TFF1, AMPH, FOXJ1, CDKN1A, EBI3, PRKCB

Free Radical Scavenging 7.49E-03-2.04E-02 SESN1, NCF1, CD40, NQO1, CDKN1A, FDXR, FAS, PRKCB Energy Production 9.43E-03-1.51E-02 CD40, NQO1, FAS Organismal Injury and Abnormalities 9.43E-03-2.69E-02 CALR, NCF1, TUBB3, CDKN1A, MDM2, TUBA1C, FAS, INPP5D, AHR, PRKCB CD40, TFF1, CDKN1A, GDF15, PBX1, ATP4A, MDM2, DDB2, GLI1, EBI3, AHR, Tumor Morphology 1.05E-02-2.38E-02 FAS Digestive System Development and Function 1.07E-02-1.07E-02 CBFB, HES1, RUNX1, AHR Hepatic System Development and Function 1.07E-02-1.07E-02 CBFB, HES1, RUNX1, AHR Organ Development 1.07E-02-2.37E-02 CBFB, HES1, RUNX1, GLI1, AHR

EFR3A, DPYD, NRXN3, PBX1, ATP4A, GON4L, ANK1, PON1, SNRPN, MYRIP, CCDC50, FHL2, AMPH, TNFRSF10C, TUBA1C, FAM65B, AHR, MYO6, TUBB3, SGCG, PRICKLE2, TNFRSF10B, SLC4A7, UBE2S, LAX1, NCF1, MNT, PSD3, Cardiovascular Disease 1.42E-02-2.47E-02 CD40, RAPH1, LRP8, DHFR, KIAA1370, FAS, TYW1, MACF1, HHAT, DNAH5, GARNL3, TULP4, RPS3, SOX5 (includes EG:6660), CALR, KCNK17, ATP1B1, CKM, ATG10, MDM2, CSGALNACT1, DNM1, KCTD10 (includes EG:83892), CDKN1A, COL24A1, GLDC, PRKCB

Amino Acid Metabolism 1.51E-02-1.51E-02 ISCU, DHFR Auditory Disease 1.51E-02-2.66E-02 MYO6, CCDC50, PBX1 Cardiovascular System Development and 1.51E-02-2.09E-02 NCF1, MEF2C, RUNX1, FAS, VASP, AHR Function CALR, PBX1, TREM2, INPP5D, FAS, NCF1, HP, MNT, APOBEC3F, TFF1, SP140, Cell-mediated Immune Response 1.51E-02-2.76E-02 CD40, AMPH, CDKN1A, CBFB, RUNX1, EBI3, AHR, PRKCB Drug Metabolism 1.51E-02-1.51E-02 DPYD, PPP1R1B, NQO1, DHFR, AHR Endocrine System Development and Function 1.51E-02-2.37E-02 HES1, GLI1, AHR Hypersensitivity Response 1.51E-02-1.51E-02 NDST2 Infection Mechanism 1.51E-02-1.51E-02 SSB CALR, TREM2, FAS, INPP5D, NCF1, HP, MNT, APOBEC3F, TFF1, SP140, CD40, Inflammatory Response 1.51E-02-2.96E-02 AMPH, EBI3, PRKCB Lymphoid Tissue Structure and Development 1.51E-02-2.69E-02 MNT, CDKN1A, L1CAM, INPP5D Post-Translational Modification 1.51E-02-1.59E-02 HHAT, ATG10, VASP RNA Post-Transcriptional Modification 1.51E-02-1.51E-02 SSB Renal and Urological Disease 1.51E-02-1.81E-02 DNM1, TRPM6, CDKN1A, FAS NQO1, PBX1, HES1, INPP5D, FAS, NCF1, MNT, CD40, CDKN1A, CBFB, RUNX1, Tissue Morphology 1.51E-02-2.66E-02 GLI1, EBI3, AHR Visual System Development and Function 1.51E-02-1.51E-02 CDKN1C Ophthalmic Disease 2.08E-02-2.37E-02 TUBB3, TUBA1C, PRKCB Infectious Disease 2.66E-02-3E-02 DNM1, TUBB3, TUBA1C, DHFR, POLE3 Protein Trafficking 2.66E-02-2.66E-02 CALR, UHMK1 Table S4: Significant differentially expressed genes (P -Value<0.05, Fold Change≥1.4), 0.4 vs. 0 Gy irradiation Genbank Fold Change P -Value Gene Symbol Description Accession 6.422507 0.006201045 NM_001957 EDNRA Homo sapiens type A (EDNRA), mRNA [NM_001957] Homo sapiens Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal 4.649178 0.036448624 NM_015365 AMMECR1 region, gene 1 (AMMECR1), transcript variant 1, mRNA [NM 015365] AA704712 zj21e01.s1 Soares_fetal_liver_spleen_1NFLS_S1 Homo sapiens cDNA clone IMAGE:450936 3', 4.4150114 0.047847 AA704712 AA704712 mRNA sequence [AA704712] YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113). 3.8298476 0.04564603 ENST00000325680 [Source:Uniprot/SWISSPROT;Acc:P49750] [ENST00000325680] 3.509828 0.004809239 AK023769 ZNF552 Homo sapiens cDNA FLJ13707 fis, clone PLACE2000347. [AK023769] 3.2365775 0.013872815 AK094842 C9orf47 Homo sapiens cDNA FLJ37523 fis, clone BRCAN2006401. [AK094842] Homo sapiens protein kinase, DNA-activated, catalytic polypeptide (PRKDC), transcript variant 1, mRNA 3.070067 0.005216093 NM_006904 PRKDC [NM 006904] 3.040723 0.025793038 AK024144 FLJ14082 Homo sapiens cDNA FLJ14082 fis, clone HEMBB1002300. [AK024144] 2.9824154 0.015273208 BX648355 GSTCD Homo sapiens mRNA; cDNA DKFZp686I10174 (from clone DKFZp686I10174). [BX648355] 2.8119144 0.045692865 NM_012188 FOXI1 Homo sapiens forkhead box I1 (FOXI1), transcript variant 1, mRNA [NM_012188] BF197320 hr78g02.x1 NCI_CGAP_Kid11 Homo sapiens cDNA clone IMAGE:3134642 3', mRNA sequence 2.7954023 0.025241178 BF197320 BF197320 [BF197320] 2.7349582 0.036284596 A_24_P256050 2.6949306 0.02500691 XM_373495 LOC387761 PREDICTED: Homo sapiens hypothetical LOC387761 (LOC387761), mRNA [XM_373495] 2.6713843 0.015825424 NM_001005234 OR1L3 Homo sapiens , family 1, subfamily L, member 3 (OR1L3), mRNA [NM_001005234] 2.650589 0.03722363 NM_182558 C12orf36 Homo sapiens chromosome 12 open reading frame 36 (C12orf36), mRNA [NM_182558] Homo sapiens ATPase, aminophospholipid transporter (APLT), Class I, type 8A, member 1 (ATP8A1), 2.6079705 0.014257268 NM_006095 ATP8A1 mRNA [NM 006095] Homo sapiens uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA), transcript variant 2, 2.586147 0.022786092 NM_001008224 UACA mRNA [NM 001008224] 2.5672915 0.016555682 ZNF488 Zinc finger protein 488. [Source:Uniprot/SWISSPROT;Acc:Q96MN9] [ENST00000298129] melanoma inhibitory activity family, member 3 [Source:RefSeq_peptide;Acc:NP_940953] 2.5546994 0.022926383 ENST00000320831 [ENST00000320831] 2.5444448 0.015916558 A_23_P71635 2.514696 0.009033358 A_32_P32876 Homo sapiens GTP cyclohydrolase 1 (dopa-responsive dystonia) (GCH1), transcript variant 1, mRNA 2.4983895 0.006337766 NM_000161 GCH1 [NM 000161] 2.4607365 0.040952053 NM_022569 NDST4 Homo sapiens N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 (NDST4), mRNA [NM_022569]

2.4375837 0.049907662 NM_006572 GNA13 Homo sapiens guanine binding protein (G protein), alpha 13 (GNA13), mRNA [NM_006572]

2.4334571 0.040123396 NM_006738 AKAP13 Homo sapiens A kinase (PRKA) anchor protein 13 (AKAP13), transcript variant 1, mRNA [NM_006738] 2.3805907 0.04877993 NM_030939 C6orf62 Homo sapiens chromosome 6 open reading frame 62 (C6orf62), mRNA [NM_030939] 2.3567243 0.030696463 NM_001003702 FLJ43692 Homo sapiens ARHGEF5-like (FLJ43692), mRNA [NM_001003702] 2.3223681 0.04453287 NM_000808 GABRA3 Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 3 (GABRA3), mRNA [NM_000808] 2.2709398 0.015688704 AJ488204 NAV2 Homo sapiens partial mRNA for steerin2 protein (STEERIN2 gene), alternative 1c. [AJ488204] Homo sapiens cDNA FLJ43271 fis, clone KIDNE2002882, highly similar to Homo sapiens Cadherin. 2.2454102 0.047179125 AK125261 FLJ23834 [AK125261] 2.236886 0.006139733 NM_002874 RAD23B Homo sapiens RAD23 homolog B (S. cerevisiae) (RAD23B), mRNA [NM_002874] 2.22177 0.042608745 A_24_P332754 2.2151523 0.006604771 NM_007129 ZIC2 Homo sapiens Zic family member 2 (odd-paired homolog, Drosophila) (ZIC2), mRNA [NM_007129] Homo sapiens elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3 (ELOVL3), 2.1721487 0.030159706 NM_152310 ELOVL3 mRNA [NM 152310] 2.161681 0.015203247 A_24_P660797 2.1424994 0.017102886 NM_152263 TPM3 Homo sapiens tropomyosin 3 (TPM3), transcript variant 1, mRNA [NM_152263] 2.142446 0.04790001 NM_145652 WFDC5 Homo sapiens WAP four-disulfide core domain 5 (WFDC5), mRNA [NM_145652] Homo sapiens solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), 2.112625 0.028865531 NM_004170 SLC1A1 member 1 (SLC1A1), mRNA [NM 004170] 2.1021054 0.027383665 NM_003299 HSP90B1 Homo sapiens heat shock protein 90kDa beta (Grp94), member 1 (HSP90B1), mRNA [NM_003299] PREDICTED: Homo sapiens similar to Protein SET (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template- 2.089297 0.010997305 XR_019178 LOC642737 activating factor I) (TAF-I) (HLA-DR-associated protein II) (PHAPII) (Inhibitor of granzyme A-activated DNase) (IGAAD) (LOC642737), mRNA [XR 019178] 2.0792327 0.019532844 NM_181354 OXR1 Homo sapiens oxidation resistance 1 (OXR1), mRNA [NM_181354] 2.0775745 0.025689056 NM_014961 RUFY3 Homo sapiens RUN and FYVE domain containing 3 (RUFY3), transcript variant 2, mRNA [NM_014961] 2.076298 0.036659803 NM_015252 EHBP1 Homo sapiens EH domain binding protein 1 (EHBP1), mRNA [NM_015252] 2.0718997 0.030089103 NM_182314 ENOX2 Homo sapiens cytosolic ovarian carcinoma antigen 1 (COVA1), transcript variant 2, mRNA [NM_182314] 2.0699623 0.015358252 NM_178439 GMCL1 Homo sapiens germ cell-less homolog 1 (Drosophila) (GMCL1), mRNA [NM_178439] 2.0631077 0.04758402 NM_003850 SUCLA2 Homo sapiens succinate-CoA ligase, ADP-forming, beta subunit (SUCLA2), mRNA [NM_003850] 2.05866 0.027163906 NM_174907 PPP4R2 Homo sapiens protein phosphatase 4, regulatory subunit 2 (PPP4R2), mRNA [NM_174907] 2.0482044 0.04889668 NM_017554 PARP14 Homo sapiens poly (ADP-ribose) polymerase family, member 14 (PARP14), mRNA [NM_017554] Homo sapiens CAP-GLY domain containing linker protein 1 (CLIP1), transcript variant 1, mRNA 2.0420299 0.03852564 NM_002956 CLIP1 [NM 002956] Homo sapiens ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) (ATP5G3), 2.0357177 0.040841334 NM_001002258 ATP5G3 nuclear gene encoding mitochondrial protein, transcript variant 3, mRNA [NM_001002258] 2.0322206 0.024998682 NM_001005404 YPEL2 Homo sapiens yippee-like 2 (Drosophila) (YPEL2), mRNA [NM_001005404] 2.0120132 0.038039345 NM_182515 ZNF714 Homo sapiens zinc finger protein 714 (ZNF714), mRNA [NM_182515] 2.0115428 0.004127378 NM_138467 TYW3 Homo sapiens tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) (TYW3), mRNA [NM_138467] 2.0072143 0.003422456 NM_144977 DENND1B Homo sapiens DENN/MADD domain containing 1B (DENND1B), mRNA [NM_144977] 1.9986916 0.017820233 NM_001661 ARL4D Homo sapiens ADP-ribosylation factor-like 4D (ARL4D), mRNA [NM_001661] 1.9922199 0.016036352 NM_032933 C18orf45 Homo sapiens open reading frame 45 (C18orf45), mRNA [NM_032933] 1.9921232 0.0455158 NM_001338 CXADR Homo sapiens coxsackie virus and adenovirus receptor (CXADR), mRNA [NM_001338] 1.9881845 0.017644338 NM_001081472 SPATA1 Homo sapiens spermatogenesis associated 1 (SPATA1), mRNA [NM_001081472] 1.9731764 0.012370945 NM_001012506 CCDC66 Homo sapiens coiled-coil domain containing 66 (CCDC66), mRNA [NM_001012506] BI836739 603089686F1 NIH_MGC_120 Homo sapiens cDNA clone IMAGE:5228685 5', mRNA sequence 1.9705752 0.017120779 BI836739 BI836739 [BI836739] 1.9670198 0.034868043 A_24_P15803 1.9649118 0.011354744 AK091914 AK091914 Homo sapiens cDNA FLJ34595 fis, clone KIDNE2009180. [AK091914] 1.9557562 0.0315688 NM_005559 LAMA1 Homo sapiens laminin, alpha 1 (LAMA1), mRNA [NM_005559] 1.9515316 0.00348288 NM_022101 CXorf56 Homo sapiens chromosome X open reading frame 56 (CXorf56), mRNA [NM_022101] 1.951421 0.042941898 NM_018962 DSCR6 Homo sapiens critical region gene 6 (DSCR6), mRNA [NM_018962] 1.9450523 0.03817284 NM_206921 C6orf204 Homo sapiens chromosome 6 open reading frame 204 (C6orf204), transcript variant 2, mRNA [NM_206921] 1.9414302 0.04520783 A_23_P72330 Homo sapiens , regulatory (inhibitor) subunit 8 (PPP1R8), transcript variant 2, mRNA 1.9344707 0.03288536 NM_138558 PPP1R8 [NM 138558] 1.9306263 0.018344864 NM_007011 ABHD2 Homo sapiens abhydrolase domain containing 2 (ABHD2), transcript variant 1, mRNA [NM_007011] 1.9299912 0.005489271 NM_003379 VIL2 Homo sapiens villin 2 (ezrin) (VIL2), mRNA [NM_003379] Homo sapiens serpin peptidase inhibitor, clade B (ovalbumin), member 9 (SERPINB9), mRNA 1.9279705 0.03222747 NM_004155 SERPINB9 [NM 004155] Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 3 (SLC2A3), mRNA 1.922957 0.02797482 NM_006931 SLC2A3 [NM 006931] 1.9183146 0.0131947 A_24_P272503 1.9158912 0.018828893 NM_005708 GPC6 Homo sapiens glypican 6 (GPC6), mRNA [NM_005708] 1.9102767 0.025841672 NM_175866 UHMK1 Homo sapiens U2AF homology motif (UHM) kinase 1 (UHMK1), mRNA [NM_175866] 1.9087348 0.010062886 NM_014607 UBXD2 Homo sapiens UBX domain containing 2 (UBXD2), mRNA [NM_014607] 1.907524 0.02678078 NM_002754 MAPK13 Homo sapiens mitogen-activated protein kinase 13 (MAPK13), mRNA [NM_002754] 1.9014188 0.045238063 CR749646 EXTL3 Homo sapiens mRNA; cDNA DKFZp686C2342 (from clone DKFZp686C2342). [CR749646] 1.9011579 0.007728174 CV326037 CV326037 CV326037 CM4-MT0289-010201-842-d08 MT0289 Homo sapiens cDNA, mRNA sequence [CV326037] 1.8973438 0.019170579 NM_018151 RIF1 Homo sapiens RAP1 interacting factor homolog (yeast) (RIF1), mRNA [NM_018151] 1.8951782 0.00371349 A_24_P752362 Homo sapiens heat shock 60kDa protein 1 (chaperonin) (HSPD1), nuclear gene encoding mitochondrial 1.8906997 0.007387557 NM_002156 HSPD1 protein, transcript variant 1, mRNA [NM 002156] 1.8862624 0.03549133 NM_024533 CHST5 Homo sapiens carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 (CHST5), mRNA [NM_024533] 1.8814131 0.008507275 NM_133458 ZFP90 Homo sapiens zinc finger protein 90 homolog (mouse) (ZFP90), mRNA [NM_133458] 1.8809648 0.014920599 NM_001661 ARL4D Homo sapiens ADP-ribosylation factor-like 4D (ARL4D), mRNA [NM_001661] 1.8729768 0.02391594 NM_005845 ABCC4 Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (ABCC4), mRNA [NM_005845] 1.8527282 0.009513002 NM_017775 TTC19 Homo sapiens tetratricopeptide repeat domain 19 (TTC19), mRNA [NM_017775] 1.8506845 3.27E-04 NM_032167 RUNDC2A Homo sapiens RUN domain containing 2A (RUNDC2A), mRNA [NM_032167] 1.8358246 0.032407112 NM_004772 C5orf13 Homo sapiens open reading frame 13 (C5orf13), mRNA [NM_004772] 1.8319484 0.031014552 NM_017774 CDKAL1 Homo sapiens CDK5 regulatory subunit associated protein 1-like 1 (CDKAL1), mRNA [NM_017774] Homo sapiens aldehyde dehydrogenase 3 family, member B2 (ALDH3B2), transcript variant 1, mRNA 1.8313094 0.013758775 NM_000695 ALDH3B2 [NM 000695] 1.830266 0.036906056 NM_025190 KIAA1641 Homo sapiens KIAA1641 (KIAA1641), mRNA [NM_025190] Ankyrin repeat domain-containing protein 36A. [Source:Uniprot/SWISSPROT;Acc:Q6UX02] 1.8273773 0.036573526 ENST00000288911 [ENST00000288911] 1.8263024 0.013827062 AF161533 HSPC048 Homo sapiens HSPC048 mRNA, complete cds. [AF161533] 1.8243935 0.03044338 BG002504 BG002504 BG002504 MR3-GN0186-171100-005-c08 GN0186 Homo sapiens cDNA, mRNA sequence [BG002504] Homo sapiens alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae), 1.8148787 0.01608962 BC002521 ATRX mRNA (cDNA clone IMAGE:3139907), complete cds. [BC002521] 1.8146584 0.002395597 NM_018566 YOD1 Homo sapiens YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae) (YOD1), mRNA [NM_018566] 1.8141881 0.008806508 AK096548 CEP192 Homo sapiens cDNA FLJ39229 fis, clone OCBBF2007414. [AK096548] 1.8123325 0.048380263 NM_000379 XDH Homo sapiens xanthine dehydrogenase (XDH), mRNA [NM_000379] Probable cation-transporting ATPase 13A3 (EC 3.6.3.-) (ATPase family homolog up-regulated in senescence 1.8092414 0.00446554 ATP13A3 cells 1). [Source:Uniprot/SWISSPROT;Acc:Q9H7F0] [ENST00000256031] 1.8062477 0.02437372 NM_024719 GRTP1 Homo sapiens growth hormone regulated TBC protein 1 (GRTP1), mRNA [NM_024719] 1.8020433 0.023279188 BC031698 FLJ40330 Homo sapiens cDNA clone IMAGE:5167446. [BC031698] 1.8005464 0.001350284 NM_006310 NPEPPS Homo sapiens aminopeptidase puromycin sensitive (NPEPPS), mRNA [NM_006310] 1.7997673 0.017261589 NM_003666 BLZF1 Homo sapiens basic nuclear factor 1 (JEM-1) (BLZF1), mRNA [NM_003666] 1.799529 0.012024007 BX647217 HNRPA3 Homo sapiens mRNA; cDNA DKFZp779E0216 (from clone DKFZp779E0216). [BX647217] ov26b05.x1 Soares_testis_NHT Homo sapiens cDNA clone IMAGE:1638417 3' similar to gb:M16660 HEAT 1.7991742 0.022346346 AI015919 AI015919 SHOCK PROTEIN HSP 90-BETA (HUMAN);, mRNA sequence [AI015919] Homo sapiens ARP2 actin-related protein 2 homolog (yeast) (ACTR2), transcript variant 1, mRNA 1.7974155 0.011082727 NM_001005386 ACTR2 [NM 001005386] Homo sapiens (prosome, macropain) 26S subunit, non-ATPase, 11 (PSMD11), mRNA 1.79331 7.69E-04 NM_002815 PSMD11 [NM 002815] 1.786903 0.041115806 NM_001005861 RYK Homo sapiens RYK receptor-like tyrosine kinase (RYK), transcript variant 1, mRNA [NM_001005861] 1.7855488 0.029999394 NM_014238 KSR1 Homo sapiens kinase suppressor of ras 1 (KSR1), mRNA [NM_014238] 1.7811202 0.019878592 NM_018307 RHOT1 Homo sapiens ras homolog , member T1 (RHOT1), transcript variant 3, mRNA [NM_018307] 1.7790227 0.04791899 NM_144711 KLHL23 Homo sapiens kelch-like 23 (Drosophila) (KLHL23), mRNA [NM_144711] 1.7781243 0.002533356 NM_014730 KIAA0152 Homo sapiens KIAA0152 (KIAA0152), mRNA [NM_014730] 1.771274 0.04906523 NM_004685 MTMR6 Homo sapiens myotubularin related protein 6 (MTMR6), mRNA [NM_004685] 1.7653207 0.019749649 NM_006425 SLU7 Homo sapiens SLU7 splicing factor homolog (S. cerevisiae) (SLU7), mRNA [NM_006425] 1.7652657 0.02972988 NM_025190 KIAA1641 Homo sapiens KIAA1641 (KIAA1641), mRNA [NM_025190] 1.7642579 0.042743217 NM_017910 FLJ20628 Homo sapiens hypothetical protein FLJ20628 (FLJ20628), mRNA [NM_017910] Homo sapiens calcium/calmodulin-dependent protein kinase (CaM kinase) II delta (CAMK2D), transcript 1.7620199 0.012599627 NM_001221 CAMK2D variant 3, mRNA [NM 001221] 1.7554128 0.021578629 NM_006241 PPP1R2 Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 2 (PPP1R2), mRNA [NM_006241] 1.7537956 0.005077223 S67659 S67659 calnexin [human, melanoma cells, SK MEL 23, mRNA Partial, 816 nt]. [S67659] 1.75348 0.0342914 NM_001040285 PAPD5 Homo sapiens PAP associated domain containing 5 (PAPD5), transcript variant 2, mRNA [NM_001040285] 1.747465 0.033678845 NM_004130 GYG1 Homo sapiens 1 (GYG1), mRNA [NM_004130] 1.7462246 0.010920444 NM_002822 TWF1 Homo sapiens twinfilin, actin-binding protein, homolog 1 (Drosophila) (TWF1), mRNA [NM_002822] Homo sapiens -related cell adhesion molecule 1 (biliary glycoprotein) 1.7389086 0.01301022 NM_001712 CEACAM1 (CEACAM1), transcript variant 1, mRNA [NM 001712] 1.7386552 0.039095882 NM_002024 FMR1 Homo sapiens fragile X mental retardation 1 (FMR1), mRNA [NM_002024] Homo sapiens RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) (RRN3), mRNA 1.7384348 0.020384831 NM_018427 RRN3 [NM 018427] Homo sapiens centrosome and spindle pole associated protein 1 (CSPP1), transcript variant 2, mRNA 1.73807 0.04127402 NM_024790 CSPP1 [NM 024790] 1.7377532 0.01893232 NM_003376 VEGFA Homo sapiens vascular endothelial growth factor A (VEGFA), transcript variant 2, mRNA [NM_003376] Homo sapiens membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) (MPP5), mRNA 1.7241894 0.025276097 NM_022474 MPP5 [NM 022474] 1.7229692 0.021598643 A_32_P104995 1.7141744 0.002124818 NM_001307 CLDN7 Homo sapiens claudin 7 (CLDN7), mRNA [NM_001307] Homo sapiens clone B4-E11 carcinoma associated protein HOJ-1 mRNA, complete cds, alternatively spliced. 1.713925 0.006807447 AY665468 RASSF8 [AY665468] 1.7052013 0.034898635 THC2477828 1.7025872 0.010805693 A_24_P384196 1.6955684 0.017766422 NM_145280 FAM119A Homo sapiens family with sequence similarity 119, member A (FAM119A), mRNA [NM_145280] 1.6950852 0.00266802 NM_001013631 HNRPCL1 Homo sapiens heterogeneous nuclear ribonucleoprotein C-like 1 (HNRPCL1), mRNA [NM_001013631] PREDICTED: Homo sapiens similar to H protein, mitochondrial precursor 1.691559 0.010693407 hCG_1642425 (LOC731353), mRNA [XR 015882] 1.6904789 0.03631483 AY956764 HSP90AB3P Homo sapiens heat shock protein 90Bc (HSP90Bc) mRNA, complete cds. [AY956764] 1.6873463 0.01811349 NM_003766 BECN1 Homo sapiens beclin 1 (coiled-coil, myosin-like BCL2 interacting protein) (BECN1), mRNA [NM_003766] 1.6835064 0.040032443 NM_152279 ZNF585B Homo sapiens zinc finger protein 585B (ZNF585B), mRNA [NM_152279] 1.682747 0.047511473 NM_005437 NCOA4 Homo sapiens nuclear receptor coactivator 4 (NCOA4), mRNA [NM_005437] 1.6822181 0.04908801 NM_032130 C12orf25 Homo sapiens chromosome 12 open reading frame 25 (C12orf25), mRNA [NM_032130] 1.6783762 0.008982316 A_24_P887805 1.6769893 0.015880372 NM_001012398 AKTIP Homo sapiens AKT interacting protein (AKTIP), transcript variant 1, mRNA [NM_001012398] 1.6769221 0.023328679 NM_007001 SLC35D2 Homo sapiens solute carrier family 35, member D2 (SLC35D2), mRNA [NM_007001] 1.6763885 0.031184988 A_24_P315644 Homo sapiens adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 1.6755822 0.04902207 NM_012096 APPL1 (APPL1), mRNA [NM 012096] 1.6731983 0.02161657 NM_152446 C14orf145 Homo sapiens open reading frame 145 (C14orf145), mRNA [NM_152446] 1.6695981 0.036903106 NM_138775 ALKBH8 Homo sapiens alkB, alkylation repair homolog 8 (E. coli) (ALKBH8), mRNA [NM_138775] 1.6683084 0.04663718 NM_019063 EML4 Homo sapiens echinoderm microtubule associated protein like 4 (EML4), mRNA [NM_019063] 1.6668246 0.011223093 A_24_P93184 Homo sapiens heat shock protein 90kDa alpha (cytosolic), class B member 1 (HSP90AB1), mRNA 1.6663573 0.030727817 NM_007355 HSP90AB1 [NM 007355] 1.6659422 0.006252552 NM_053036 NPFFR2 Homo sapiens neuropeptide FF receptor 2 (NPFFR2), transcript variant 2, mRNA [NM_053036] 1.6658518 0.03152216 NR_001446 ANXA2P3 Homo sapiens annexin A2 3 (ANXA2P3) on [NR_001446] 1.6651391 0.04039556 NM_002000 FCAR Homo sapiens Fc fragment of IgA, receptor for (FCAR), transcript variant 1, mRNA [NM_002000] 1.6609621 0.029426042 NM_032558 HIATL1 Homo sapiens hippocampus abundant transcript-like 1 (HIATL1), mRNA [NM_032558] 1.6605817 0.012697254 A_32_P136477 Homo sapiens 6, apoptosis-related peptidase (CASP6), transcript variant alpha, mRNA 1.656225 0.020249791 NM_001226 CASP6 [NM 001226] 1.655919 0.03323601 M95923 ALOX15 Human 12-lipoxygenase mRNA, partial cds. [M95923] 1.6533854 0.027149174 NM_005180 BMI1 Homo sapiens BMI1 polycomb ring finger oncogene (BMI1), mRNA [NM_005180] 1.6507603 0.005042547 THC2650423 1.6494116 0.038505007 NM_153649 TPM3 Homo sapiens tropomyosin 3 (TPM3), transcript variant 2, mRNA [NM_153649] PEBP_MOUSE (P70296) Phosphatidylethanolamine-binding protein (PEBP) (HCNPpp) [Contains: 1.6456463 0.046958063 THC2651548 Hippocampal cholinergic neurostimulating peptide (HCNP)], complete [THC2651548] 1.6438704 0.02100755 NM_001083 PDE5A Homo sapiens 5A, cGMP-specific (PDE5A), transcript variant 1, mRNA [NM_001083] 1.6427721 0.01661028 NM_033319 CENPL Homo sapiens centromere protein L (CENPL), mRNA [NM_033319] 1.6425864 0.015478937 A_24_P623631 1.6406235 0.023362286 NM_006965 ZNF24 Homo sapiens zinc finger protein 24 (ZNF24), mRNA [NM_006965] 1.6403184 0.04245024 NM_005749 TOB1 Homo sapiens transducer of ERBB2, 1 (TOB1), mRNA [NM_005749] 1.640138 0.037103713 NM_000876 IGF2R Homo sapiens insulin-like growth factor 2 receptor (IGF2R), mRNA [NM_000876] 1.6368353 0.001177719 NM_020240 CDC42SE2 Homo sapiens CDC42 small effector 2 (CDC42SE2), transcript variant 1, mRNA [NM_020240] 1.6310012 0.04444624 NM_020644 TMEM9B Homo sapiens TMEM9 domain family, member B (TMEM9B), mRNA [NM_020644] 1.6306636 0.032672953 NM_015938 NMD3 Homo sapiens NMD3 homolog (S. cerevisiae) (NMD3), mRNA [NM_015938] 1.6281543 0.001096527 BC022830 LOC642852 Homo sapiens hypothetical LOC642852, mRNA (cDNA clone IMAGE:4581955), partial cds. [BC022830] 1.6278535 0.03871671 NM_001012398 AKTIP Homo sapiens AKT interacting protein (AKTIP), transcript variant 1, mRNA [NM_001012398] 1.6273108 0.04014106 NM_152909 ZNF548 Homo sapiens zinc finger protein 548 (ZNF548), mRNA [NM_152909] 1.6225394 0.02793661 AK094893 LOC645431 Homo sapiens cDNA FLJ37574 fis, clone BRCOC2003100. [AK094893] 1.6215904 0.009816128 NM_174881 CRB3 Homo sapiens crumbs homolog 3 (Drosophila) (CRB3), transcript variant 3, mRNA [NM_174881] 1.6172271 0.020522023 NM_153649 TPM3 Homo sapiens tropomyosin 3 (TPM3), transcript variant 2, mRNA [NM_153649] 1.6123048 0.010363488 NM_002228 JUN Homo sapiens jun oncogene (JUN), mRNA [NM_002228] 1.6048623 0.038812008 NM_016519 AMBN Homo sapiens ameloblastin (enamel matrix protein) (AMBN), mRNA [NM_016519] 1.6045974 0.03940541 AK074291 AK074291 Homo sapiens cDNA FLJ23711 fis, clone HEP12371. [AK074291] 1.6043535 0.003802486 NM_014408 TRAPPC3 Homo sapiens trafficking protein particle complex 3 (TRAPPC3), mRNA [NM_014408] 1.6002663 0.034708563 NM_001039775 FLJ38020 Homo sapiens similar to absent in melanoma 1 (FLJ38020), mRNA [NM_001039775] 1.5992678 0.046460107 NM_033406 FBXO3 Homo sapiens F-box protein 3 (FBXO3), transcript variant 2, mRNA [NM_033406] Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1). 1.5979389 0.018988771 ENST00000366699 [Source:Uniprot/SWISSPROT;Acc:Q96F44] [ENST00000366699] similar to family with sequence similarity 35, member A (LOC439965), misc RNA 1.5970978 0.030928675 ENST00000301038 [Source:RefSeq dna;Acc:XR 015353] [ENST00000301038] Homo sapiens golgi autoantigen, golgin subfamily a, 7 (GOLGA7), transcript variant 2, mRNA 1.5964869 0.012846118 NM_001002296 GOLGA7 [NM 001002296] 1.5950489 0.029538862 NM_031407 HUWE1 Homo sapiens HECT, UBA and WWE domain containing 1 (HUWE1), mRNA [NM_031407] 1.5929766 0.007939008 NM_199132 ZNF468 Homo sapiens zinc finger protein 468 (ZNF468), transcript variant 1, mRNA [NM_199132] 1.5924997 0.002164439 NM_000112 SLC26A2 Homo sapiens solute carrier family 26 (sulfate transporter), member 2 (SLC26A2), mRNA [NM_000112] 1.586994 0.005549039 AF074986 AF074986 Homo sapiens full length insert cDNA YH73H08. [AF074986] 1.5857731 0.038992573 THC2750781 1.5845343 0.026750892 NM_032357 CCDC115 Homo sapiens coiled-coil domain containing 115 (CCDC115), mRNA [NM_032357] 1.5837997 0.013299099 NM_152556 FLJ31818 Homo sapiens hypothetical protein FLJ31818 (FLJ31818), mRNA [NM_152556] 1.5836853 0.003290349 NM_003362 UNG Homo sapiens uracil-DNA glycosylase (UNG), transcript variant 1, mRNA [NM_003362] 1.5825186 0.04080775 NM_182488 USP12 Homo sapiens ubiquitin specific peptidase 12 (USP12), mRNA [NM_182488] 1.581747 0.025407301 AF147398 AF147398 Homo sapiens full length insert cDNA clone YI64E10. [AF147398] 1.5814493 0.01941685 NM_020639 RIPK4 Homo sapiens receptor-interacting serine-threonine kinase 4 (RIPK4), mRNA [NM_020639] 1.580904 0.034450255 NM_032584 ZNF347 Homo sapiens zinc finger protein 347 (ZNF347), mRNA [NM_032584] Homo sapiens electron-transfer-, alpha polypeptide (glutaric aciduria II) (ETFA), nuclear gene 1.5790749 0.02694676 NM_000126 ETFA encoding mitochondrial protein, mRNA [NM 000126] 1.5763487 0.037227985 NM_014899 RHOBTB3 Homo sapiens Rho-related BTB domain containing 3 (RHOBTB3), mRNA [NM_014899] 1.5733649 0.03908496 NM_176895 PPAP2A Homo sapiens phosphatidic type 2A (PPAP2A), transcript variant 2, mRNA [NM_176895] 1.5723561 0.044029433 NR_003128 LOC284441 Homo sapiens actin-related protein 2 pseudogene (LOC284441) on chromosome 19 [NR_003128] 1.568969 0.021727776 NM_005626 SFRS4 Homo sapiens splicing factor, /serine-rich 4 (SFRS4), mRNA [NM_005626] Homo sapiens CCR4-NOT transcription complex, subunit 7 (CNOT7), transcript variant 2, mRNA 1.5683299 0.033107128 NM_054026 CNOT7 [NM 054026] 1.5641594 0.022230737 NM_001007527 LMBRD2 Homo sapiens LMBR1 domain containing 2 (LMBRD2), mRNA [NM_001007527] 1.5639648 0.03722911 NM_003314 TTC1 Homo sapiens tetratricopeptide repeat domain 1 (TTC1), mRNA [NM_003314] Homo sapiens nuclear casein kinase and cyclin-dependent kinase 1 (NUCKS1), mRNA 1.5637509 0.03390964 NM_022731 NUCKS1 [NM 022731] 1.5605572 0.023755763 NM_005370 RAB8A Homo sapiens RAB8A, member RAS oncogene family (RAB8A), mRNA [NM_005370] 1.5598325 0.009520243 NM_020240 CDC42SE2 Homo sapiens CDC42 small effector 2 (CDC42SE2), transcript variant 1, mRNA [NM_020240] AI500335 tm95e03.x1 NCI_CGAP_Brn25 Homo sapiens cDNA clone IMAGE:2165884 3', mRNA sequence 1.5592515 0.027159605 THC2669063 [AI500335] 1.5545456 0.026411321 ENST00000318301 Homo sapiens v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) (RALB), 1.552934 0.03586531 NM_002881 RALB mRNA [NM 002881] 1.5529252 0.045761105 A_24_P562242 1.5529131 0.011078971 NM_018229 C14orf108 Homo sapiens chromosome 14 open reading frame 108 (C14orf108), mRNA [NM_018229] 1.5528742 0.0101315 NM_144982 CCDC131 Homo sapiens coiled-coil domain containing 131 (CCDC131), mRNA [NM_144982] BRI3-binding protein (I3-binding protein) (Cervical cancer 1 proto- oncogene-binding protein KG19) (HCCR- 1.5465682 0.006667745 BRI3BP 1). [Source:Uniprot/SWISSPROT;Acc:Q8WY22] [ENST00000332107] Homo sapiens BRCA1/BRCA2-containing complex, subunit 3 (BRCC3), transcript variant 2, mRNA 1.5456266 0.033751924 NM_001018055 BRCC3 [NM 001018055] 1.5455759 0.007431255 BF969441 BF969441 602271732F1 NIH_MGC_84 Homo sapiens cDNA clone IMAGE:4360158 5', mRNA sequence [BF969441]

1.5452868 0.034656633 AF128541 POLE Homo sapiens DNA polymerase epsilon catalytic subunit isoform a (POLE1) mRNA, partial cds. [AF128541] 1.5445273 0.027797904 A_32_P231743 1.5435764 0.032399356 NM_005056 JARID1A Homo sapiens jumonji, AT rich interactive domain 1A (JARID1A), transcript variant 2, mRNA [NM_005056] 1.5422913 0.044285394 NM_177966 2'-PDE Homo sapiens 2'-phosphodiesterase (2'-PDE), mRNA [NM_177966] 1.5409416 0.007366484 NM_001738 CA1 Homo sapiens carbonic anhydrase I (CA1), mRNA [NM_001738] 1.5346646 0.04635522 NM_178828 C9orf79 Homo sapiens chromosome 9 open reading frame 79 (C9orf79), mRNA [NM_178828] 1.5343498 0.038892947 BC018676 BC018676 Homo sapiens, clone IMAGE:4337652, mRNA. [BC018676] Homo sapiens beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) (B3GALNT1), 1.533844 0.027038991 NM_033169 B3GALNT1 transcript variant 4, mRNA [NM 033169] 1.5338234 0.014030677 NM_201269 ZNF644 Homo sapiens zinc finger protein 644 (ZNF644), transcript variant 1, mRNA [NM_201269] Homo sapiens fibronectin leucine rich transmembrane protein 3 (FLRT3), transcript variant 2, mRNA 1.5334438 0.006973866 NM_198391 FLRT3 [NM 198391] 1.5313733 0.005384035 NM_004438 EPHA4 Homo sapiens EPH receptor A4 (EPHA4), mRNA [NM_004438] 1.5303138 0.03296754 A_24_P622697 Homo sapiens adaptor-related protein complex 1, sigma 3 subunit, mRNA (cDNA clone MGC:17284 1.5301502 0.021218168 BC021898 AP1S3 IMAGE:4340257), complete cds. [BC021898] 1.5269911 0.039854486 NM_024081 PRRG4 Homo sapiens proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) (PRRG4), mRNA [NM_024081] 1.5240319 0.035359155 NM_002754 MAPK13 Homo sapiens mitogen-activated protein kinase 13 (MAPK13), mRNA [NM_002754] 1.5228357 0.0407129 A_24_P633686 1.521495 0.03126412 NM_001364 DLG2 Homo sapiens discs, large homolog 2, chapsyn-110 (Drosophila) (DLG2), mRNA [NM_001364] 1.5204275 0.028002663 NM_018385 LSG1 Homo sapiens large subunit GTPase 1 homolog (S. cerevisiae) (LSG1), mRNA [NM_018385] 1.519757 0.007287579 NM_004249 RAB28 Homo sapiens RAB28, member RAS oncogene family (RAB28), transcript variant 2, mRNA [NM_004249] 1.516519 0.044248287 A_24_P333077 1.5151012 0.030612772 NM_001005372 METTL2A Homo sapiens methyltransferase like 2A (METTL2A), mRNA [NM_001005372] 1.5144278 0.018147686 NM_001003945 ALAD Homo sapiens aminolevulinate, delta-, dehydratase (ALAD), transcript variant 1, mRNA [NM_001003945] 1.5082059 0.019307334 NM_018212 ENAH Homo sapiens enabled homolog (Drosophila) (ENAH), transcript variant 2, mRNA [NM_018212] 1.507033 0.032547787 NM_005068 SIM1 Homo sapiens single-minded homolog 1 (Drosophila) (SIM1), mRNA [NM_005068] 1.5003715 0.033813227 A_24_P401392 1.4996973 8.37E-04 NM_001012391 RUNDC2B Homo sapiens RUN domain containing 2B (RUNDC2B), mRNA [NM_001012391] PREDICTED: Homo sapiens similar to DnaJ (Hsp40) homolog, subfamily C, member 8 (LOC646547), 1.4986668 0.024830742 XR_018978 LOC646547 mRNA [XR 018978] 1.4981676 0.04633752 NM_006699 MAN1A2 Homo sapiens mannosidase, alpha, class 1A, member 2 (MAN1A2), mRNA [NM_006699] 1.4964222 0.011136238 NM_004438 EPHA4 Homo sapiens EPH receptor A4 (EPHA4), mRNA [NM_004438] 1.4956315 0.03709533 XR_015785 LOC402643 PREDICTED: Homo sapiens tropomyosin 3-like (LOC402643), misc RNA [XR_015785] 1.489749 0.01792743 NM_012382 TTC33 Homo sapiens tetratricopeptide repeat domain 33 (TTC33), mRNA [NM_012382] 1.4888774 0.005239738 NM_003707 RUVBL1 Homo sapiens RuvB-like 1 (E. coli) (RUVBL1), mRNA [NM_003707] 1.4876137 0.04809144 NM_001012989 UBE2NL Homo sapiens ubiquitin-conjugating enzyme E2N-like (UBE2NL), mRNA [NM_001012989] 1.482271 0.030963618 NM_004560 ROR2 Homo sapiens receptor tyrosine kinase-like 2 (ROR2), mRNA [NM_004560] 1.4809178 0.035206538 NM_024902 FLJ13236 Homo sapiens hypothetical protein FLJ13236 (FLJ13236), mRNA [NM_024902] 1.4790922 0.023917902 NM_153649 TPM3 Homo sapiens tropomyosin 3 (TPM3), transcript variant 2, mRNA [NM_153649] 1.4769831 0.016290756 NM_152562 CDCA2 Homo sapiens cell division cycle associated 2 (CDCA2), mRNA [NM_152562] 1.476211 0.02126603 NM_001080541 MGA Homo sapiens MAX gene associated (MGA), mRNA [NM_001080541] 1.4748088 0.009443902 NM_003290 TPM4 Homo sapiens tropomyosin 4 (TPM4), mRNA [NM_003290] 1.4729748 0.01381461 NM_032560 SMEK1 Homo sapiens SMEK homolog 1, suppressor of mek1 (Dictyostelium) (SMEK1), mRNA [NM_032560] 1.46995 0.029525835 NM_001362 DIO3 Homo sapiens deiodinase, iodothyronine, type III (DIO3), mRNA [NM_001362] 1.4679201 0.016642088 A_23_P255637 1.4675891 0.010758153 XR_017206 LOC643744 PREDICTED: Homo sapiens similar to D-PCa-2 c (LOC643744), mRNA [XR_017206] BX375060 Homo sapiens NEUROBLASTOMA COT 25-NORMALIZED Homo sapiens cDNA clone 1.4671836 0.005159763 BX375060 BX375060 CS0DC007YF13 5-PRIME, mRNA sequence [BX375060] 1.4664974 0.018939212 NM_004901 ENTPD4 Homo sapiens ectonucleoside triphosphate diphosphohydrolase 4 (ENTPD4), mRNA [NM_004901] 1.4655223 0.017255293 NM_144723 ZMAT2 Homo sapiens zinc finger, matrin type 2 (ZMAT2), mRNA [NM_144723] 1.4642974 0.007353132 NM_001004317 LIN28B Homo sapiens lin-28 homolog B (C. elegans) (LIN28B), mRNA [NM_001004317] 1.4637223 0.015202756 NM_024625 ZC3HAV1 Homo sapiens zinc finger CCCH-type, antiviral 1 (ZC3HAV1), transcript variant 2, mRNA [NM_024625] 1.4627925 0.026769837 NM_005707 PDCD7 Homo sapiens programmed cell death 7 (PDCD7), mRNA [NM_005707] Receptor expression-enhancing protein 3. [Source:Uniprot/SWISSPROT;Acc:Q6NUK4] 1.4622862 0.041830145 REEP3 [ENST00000298249] Homo sapiens mitochondrial ribosomal protein S23 (MRPS23), nuclear gene encoding mitochondrial protein, 1.4614185 0.038186885 NM_016070 MRPS23 mRNA [NM 016070] 1.4612046 0.034220744 NM_175075 C8orf42 Homo sapiens chromosome 8 open reading frame 42 (C8orf42), mRNA [NM_175075] 1.4603717 0.005945326 A_24_P903715 1.4601494 0.013035401 NM_152994 CCDC128 Homo sapiens coiled-coil domain containing 128 (CCDC128), mRNA [NM_152994] 1.459463 0.042221162 NR_002190 SUMO1P3 Homo sapiens SUMO1 pseudogene 3 (SUMO1P3) on chromosome 1 [NR_002190] BF593129 7o49h09.x1 NCI_CGAP_Kid11 Homo sapiens cDNA clone IMAGE:3577600 3', mRNA sequence 1.4542642 0.004137477 BF593129 BF593129 [BF593129] 1.4528013 0.03635396 XR_017499 LOC647211 PREDICTED: Homo sapiens similar to rhophilin-like protein (LOC647211), mRNA [XR_017499] 1.4516375 0.030725557 NM_005840 SPRY3 Homo sapiens sprouty homolog 3 (Drosophila) (SPRY3), mRNA [NM_005840] Homo sapiens cDNA FLJ13703 fis, clone PLACE2000246, weakly similar to RING CANAL PROTEIN. 1.4503317 0.00854254 AK023765 KLHL18 [AK023765] 1.4485683 0.003926326 NM_080662 PEX11G Homo sapiens peroxisomal biogenesis factor 11 gamma (PEX11G), mRNA [NM_080662] Homo sapiens Zwilch, kinetochore associated, homolog (Drosophila) (ZWILCH), transcript variant 1, mRNA 1.4462866 0.026075246 NM_017975 ZWILCH [NM 017975] Homo sapiens COX11 homolog, cytochrome c oxidase assembly protein (yeast) (COX11), nuclear gene 1.444772 0.037628774 NM_004375 COX11 encoding mitochondrial protein, mRNA [NM 004375] AI090480 qa64d05.x1 Soares_fetal_heart_NbHH19W Homo sapiens cDNA clone IMAGE:1691529 3', 1.4440218 0.027743587 THC2552322 mRNA sequence [AI090480] 1.4432123 0.044075303 AF126020 BCAP29 Homo sapiens B-cell receptor-associated protein BAP29 mRNA, complete cds. [AF126020] 1.4426522 0.023610165 NM_014280 DNAJC8 Homo sapiens DnaJ (Hsp40) homolog, subfamily C, member 8 (DNAJC8), mRNA [NM_014280] 1.4424009 0.006045549 NM_001013718 LOC441120 Homo sapiens similar to LOC285679 protein (LOC441120), mRNA [NM_001013718] 1.4407423 0.026326358 ENST00000320876 Homo sapiens, clone IMAGE:4285740, mRNA. [BC006008] 1.4406902 0.005636524 NM_032121 RP11-217H1.1 Homo sapiens implantation-associated protein (DKFZp564K142), mRNA [NM_032121] 1.4327096 0.026662484 NM_017986 GPR172B Homo sapiens G protein-coupled receptor 172B (GPR172B), mRNA [NM_017986] 1.430836 0.047087677 NM_002967 SAFB Homo sapiens scaffold attachment factor B (SAFB), mRNA [NM_002967] 1.4304259 0.026073406 NM_001017969 KIAA2026 Homo sapiens KIAA2026 (KIAA2026), mRNA [NM_001017969] Homo sapiens chromosome 10 open reading frame 4 (C10orf4), transcript variant FRA10AC1-3.3, mRNA 1.4297861 0.042172443 NM_203438 C10orf4 [NM 203438] 1.4249641 0.04104008 NM_018472 FAM45B Homo sapiens family with sequence similarity 45, member B (FAM45B), mRNA [NM_018472] MGC13part.3.1.L1.1.H03.F.1 NIH_MGC_331 Homo sapiens cDNA clone MGC13part.3.1.L1.1.H03, mRNA 1.4235746 0.04625999 EG328448 EG328448 sequence [EG328448] 1.4220871 0.009685846 AK098728 AK098728 Homo sapiens cDNA FLJ25862 fis, clone CBR01781. [AK098728] 1.4216429 0.016140731 NM_006052 DSCR3 Homo sapiens Down syndrome critical region gene 3 (DSCR3), mRNA [NM_006052] 1.419702 0.035197567 NM_007042 RPP14 Homo sapiens P 14kDa subunit (RPP14), mRNA [NM_007042] 1.4169906 0.046668496 NM_012330 MYST4 Homo sapiens MYST histone acetyltransferase (monocytic leukemia) 4 (MYST4), mRNA [NM_012330] 1.4167936 0.04096522 NM_173813 C12orf51 Homo sapiens chromosome 12 open reading frame 51 (C12orf51), mRNA [NM_173813] 1.4117941 0.018886108 NM_015622 C7orf28A Homo sapiens open reading frame 28A (C7orf28A), mRNA [NM_015622] 1.4105227 0.018962247 NM_177438 DICER1 Homo sapiens Dicer1, Dcr-1 homolog (Drosophila) (DICER1), transcript variant 1, mRNA [NM_177438]

1.4103063 0.011776539 NM_003031 SIAH1 Homo sapiens seven in absentia homolog 1 (Drosophila) (SIAH1), transcript variant 1, mRNA [NM_003031] 1.409925 0.020246793 NM_178844 NLRC3 Homo sapiens NLR family, CARD domain containing 3 (NLRC3), mRNA [NM_178844] 1.4078251 0.035172507 NM_153649 TPM3 Homo sapiens tropomyosin 3 (TPM3), transcript variant 2, mRNA [NM_153649] 1.4077144 0.035579372 NM_012373 OR3A3 Homo sapiens olfactory receptor, family 3, subfamily A, member 3 (OR3A3), mRNA [NM_012373] 1.4073467 0.049294174 NM_201430 RTN3 Homo sapiens reticulon 3 (RTN3), transcript variant 4, mRNA [NM_201430] Homo sapiens La ribonucleoprotein domain family, member 4 (LARP4), transcript variant 2, mRNA 1.4072096 0.03733709 NM_199188 LARP4 [NM 199188] 1.4061875 0.017994246 NM_020240 CDC42SE2 Homo sapiens CDC42 small effector 2 (CDC42SE2), transcript variant 1, mRNA [NM_020240] Homo sapiens mediator of RNA polymerase II transcription, subunit 28 homolog (S. cerevisiae) (MED28), 1.4061638 0.04350112 NM_025205 MED28 mRNA [NM 025205] Homo sapiens small trans-membrane and glycosylated protein (LOC57228), transcript variant 1, mRNA 1.405575 0.011093187 NM_001031628 LOC57228 [NM 001031628] 1.4053757 0.019540317 NM_014912 CPEB3 Homo sapiens cytoplasmic element binding protein 3 (CPEB3), mRNA [NM_014912] 1.4050623 0.037242793 NM_001664 RHOA Homo sapiens ras homolog gene family, member A (RHOA), mRNA [NM_001664] 1.4030632 0.012227382 NM_024911 GPR177 Homo sapiens G protein-coupled receptor 177 (GPR177), transcript variant 1, mRNA [NM_024911] 1.4008317 0.002709493 BC015370 BC015370 Homo sapiens cDNA clone IMAGE:3916023, partial cds. [BC015370] 1.4004837 0.048220124 NM_148977 PANK1 Homo sapiens pantothenate kinase 1 (PANK1), transcript variant alpha, mRNA [NM_148977] 1.4000932 0.007334044 NM_005610 RBBP4 Homo sapiens retinoblastoma binding protein 4 (RBBP4), mRNA [NM_005610] Homo sapiens dual-specificity tyrosine-(Y)- regulated kinase 3 (DYRK3), transcript variant -1.4040567 0.010383998 NM_001004023 DYRK3 2, mRNA [NM 001004023] -1.4042655 0.032198716 NM_003931 WASF1 Homo sapiens WAS , member 1 (WASF1), transcript variant 1, mRNA [NM_003931] -1.4051586 0.044319868 NM_017991 FLJ10081 Homo sapiens hypothetical protein FLJ10081 (FLJ10081), mRNA [NM_017991] -1.4072113 0.03484572 THC2706493 GLUQ_CHRVO (Q7NSJ1) Glutamyl-Q tRNA(Asp) synthetase (Glu-Q-RSs) , partial (5%) [THC2706493] RNA-binding protein 26 (RNA-binding motif protein 26) (CTCL se70-2). -1.407363 0.012300837 ENST00000377156 [Source:Uniprot/SWISSPROT;Acc:Q5T8P6] [ENST00000377156] Homo sapiens tubulin tyrosine ligase-like family, member 3 (TTLL3), transcript variant 2, mRNA -1.4114605 0.048970748 NM_015644 TTLL3 [NM 015644] -1.4137878 0.018524308 NM_145755 TTC21A Homo sapiens tetratricopeptide repeat domain 21A (TTC21A), mRNA [NM_145755] -1.4146211 0.006701658 NM_152891 PRSS33 Homo sapiens , serine, 33 (PRSS33), mRNA [NM_152891] -1.4155632 0.029960781 NM_015493 ANKRD25 Homo sapiens ankyrin repeat domain 25 (ANKRD25), mRNA [NM_015493] -1.4179887 0.011694826 BX648950 BX648950 Homo sapiens mRNA; cDNA DKFZp686E1648 (from clone DKFZp686E1648). [BX648950] Homo sapiens runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) (RUNX1), -1.4181463 0.014863898 NM_001001890 RUNX1 transcript variant 2, mRNA [NM 001001890] -1.4234028 0.04979547 NM_018638 ETNK1 Homo sapiens ethanolamine kinase 1 (ETNK1), transcript variant 1, mRNA [NM_018638] -1.4247679 0.035179384 NM_000085 CLCNKB Homo sapiens chloride channel Kb (CLCNKB), mRNA [NM_000085] -1.4260474 0.045772113 A_32_P19466 CDNA FLJ43187 fis, clone FCBBF3023443. [Source:Uniprot/SPTREMBL;Acc:Q6ZUZ4] -1.4280308 0.019083707 ENST00000355873 [ENST00000355873] -1.4343721 0.034652542 NM_001013618 CTA-246H3.1 Homo sapiens similar to omega protein (LOC91353), mRNA [NM_001013618] -1.4347504 0.033195205 BC009009 PLCB2 Homo sapiens C, beta 2, mRNA (cDNA clone IMAGE:3446252), complete cds. [BC009009] -1.4351907 0.024395604 NM_016362 GHRL Homo sapiens ghrelin/obestatin preprohormone (GHRL), mRNA [NM_016362] -1.4356022 0.008931124 AF062385 AF062385 Homo sapiens LQFBS-1 mRNA, complete cds. [AF062385] -1.4371899 0.04180185 NM_004120 GBP2 Homo sapiens guanylate binding protein 2, interferon-inducible (GBP2), mRNA [NM_004120] -1.4376463 0.015972506 AK123679 AK123679 Homo sapiens cDNA FLJ41685 fis, clone HCASM2006338. [AK123679] -1.439752 0.013154652 NM_005090 PLA2G4B Homo sapiens , group IVB (cytosolic) (PLA2G4B), mRNA [NM_005090] -1.4399645 0.047197897 AV682647 AV682647 AV682647 GKB Homo sapiens cDNA clone GKBAMG06 5', mRNA sequence [AV682647] -1.4424263 0.030142812 NM_018042 SLFN12 Homo sapiens schlafen family member 12 (SLFN12), mRNA [NM_018042] -1.4426633 0.036879897 A_23_P135063 -1.4434861 0.033042792 NM_002077 GOLGA1 Homo sapiens golgi autoantigen, golgin subfamily a, 1 (GOLGA1), mRNA [NM_002077] -1.4466617 0.030698223 NM_001819 CHGB Homo sapiens chromogranin B (secretogranin 1) (CHGB), mRNA [NM_001819] -1.4475743 0.024531525 NM_182612 PDDC1 Homo sapiens Parkinson disease 7 domain containing 1 (PDDC1), mRNA [NM_182612] -1.4533397 0.049292296 NM_005952 MT1X Homo sapiens metallothionein 1X (MT1X), mRNA [NM_005952] -1.4567842 0.04505737 NM_003717 NPFF Homo sapiens neuropeptide FF-amide peptide precursor (NPFF), mRNA [NM_003717] -1.4570701 0.00336533 AF318367 C9orf86 Homo sapiens pp8875 mRNA, complete cds. [AF318367] -1.4583697 0.03328621 NM_014427 CPNE7 Homo sapiens copine VII (CPNE7), transcript variant 2, mRNA [NM_014427] -1.4586186 0.045322046 AK057652 AK057652 Homo sapiens cDNA FLJ33090 fis, clone TRACH2000559. [AK057652] -1.4590138 0.012154136 NM_012415 RAD54B Homo sapiens RAD54 homolog B (S. cerevisiae) (RAD54B), mRNA [NM_012415] Homo sapiens vacuolar protein sorting 24 homolog (S. cerevisiae) (VPS24), transcript variant 1, mRNA -1.4601151 0.032645393 NM_016079 VPS24 [NM 016079] -1.4629493 0.046157766 A_24_P136155 -1.4639632 0.046886653 A_24_P169503 -1.4671994 0.042209405 A_24_P7494 Homo sapiens calcium channel, voltage-dependent, L type, alpha 1C subunit (CACNA1C), mRNA -1.4678764 0.03692165 NM_000719 CACNA1C [NM 000719] Homo sapiens solute carrier family 7 (cationic amino acid transporter, y+ system), member 4 (SLC7A4), -1.4721777 0.04053751 NM_004173 SLC7A4 mRNA [NM 004173] -1.4744225 0.043927316 NM_138344 C14orf152 Homo sapiens chromosome 14 open reading frame 152 (C14orf152), mRNA [NM_138344] wj89h07.x1 NCI_CGAP_Lym12 Homo sapiens cDNA clone IMAGE:2410045 3', mRNA sequence -1.4774851 0.036361407 AI818976 AI818976 [AI818976] -1.4824312 9.65E-04 NM_001039464 C1orf175 Homo sapiens chromosome 1 open reading frame 175 (C1orf175), mRNA [NM_001039464] -1.4830587 0.006673229 NM_145172 WDR63 Homo sapiens WD repeat domain 63 (WDR63), mRNA [NM_145172] -1.4864538 0.023447115 BC107568 BC107568 Homo sapiens cDNA clone IMAGE:3683736. [BC107568] -1.4878552 0.002848414 NM_024711 GIMAP6 Homo sapiens GTPase, IMAP family member 6 (GIMAP6), transcript variant 1, mRNA [NM_024711] -1.4902369 0.03398172 hCG_23177 -1.4903271 0.014184425 NM_015310 PSD3 Homo sapiens pleckstrin and Sec7 domain containing 3 (PSD3), transcript variant 1, mRNA [NM_015310]

-1.490939 0.027492018 NM_000428 LTBP2 Homo sapiens latent transforming growth factor beta binding protein 2 (LTBP2), mRNA [NM_000428] -1.4918423 0.025435545 NM_003246 THBS1 Homo sapiens thrombospondin 1 (THBS1), mRNA [NM_003246] HHAGE041070 Human liver regeneration after partial hepatectomy Homo sapiens cDNA, mRNA sequence -1.497256 0.027932107 DW443340 DW443340 [DW443340] ALU3_HUMAN (P39190) Alu subfamily SB1 sequence contamination warning entry, partial (19%) -1.5031104 0.008140772 THC2529512 [THC2529512] -1.503372 0.009255726 AK097080 AK097080 Homo sapiens cDNA FLJ39761 fis, clone SPLEN1000083. [AK097080] -1.509181 0.019867262 NM_030971 SFXN3 Homo sapiens sideroflexin 3 (SFXN3), mRNA [NM_030971] -1.5130657 0.044571694 NM_032236 USP48 Homo sapiens ubiquitin specific peptidase 48 (USP48), transcript variant 1, mRNA [NM_032236] -1.5198076 0.028962426 AK092942 AK092942 Homo sapiens cDNA FLJ35623 fis, clone SPLEN2010986. [AK092942] ALU6_HUMAN (P39193) Alu subfamily SP sequence contamination warning entry, partial (14%) -1.5233357 0.017057745 THC2650120 [THC2650120] -1.5258293 0.037117552 NM_182614 FAM70B Homo sapiens family with sequence similarity 70, member B (FAM70B), mRNA [NM_182614] -1.5277491 0.025578141 LOC145814 Homo sapiens cDNA clone IMAGE:40022889. [BC104744] -1.5295973 0.034572188 AK123446 AK123446 Homo sapiens cDNA FLJ41452 fis, clone BRSTN2010363. [AK123446] -1.5307522 0.023819227 NM_015092 SMG1 Homo sapiens PI-3-kinase-related kinase SMG-1 (SMG1), mRNA [NM_015092] -1.5346648 0.037238847 BC030084 BC030084 Homo sapiens cDNA clone IMAGE:4791887. [BC030084] -1.5389899 0.013744358 AB051442 KIAA1655 Homo sapiens mRNA for KIAA1655 protein, partial cds. [AB051442] -1.5410136 0.04320067 THC2606799 -1.5415736 0.008832176 NM_176870 MT1M Homo sapiens metallothionein 1M (MT1M), mRNA [NM_176870] -1.5421606 0.018025778 NM_004405 DLX2 Homo sapiens distal-less homeobox 2 (DLX2), mRNA [NM_004405] -1.5459586 0.00412918 NM_000835 GRIN2C Homo sapiens , ionotropic, N-methyl D-aspartate 2C (GRIN2C), mRNA [NM_000835] -1.5490288 0.04040757 BF373107 BF373107 BF373107 CM2-FT0123-280700-305-C12 FT0123 Homo sapiens cDNA, mRNA sequence [BF373107] -1.549279 0.046001464 NM_033118 MYLK2 Homo sapiens myosin chain kinase 2, skeletal muscle (MYLK2), mRNA [NM_033118] -1.5552142 0.025283042 NM_001040078 LOC654346 Homo sapiens similar to galectin 9 short isoform (LOC654346), mRNA [NM_001040078] -1.5609336 0.014765183 NM_005599 NHLH2 Homo sapiens nescient helix loop helix 2 (NHLH2), mRNA [NM_005599] -1.5675803 0.012548312 AF087999 AF087999 Homo sapiens full length insert cDNA clone YX44E03. [AF087999] -1.5676595 0.048961718 AK026155 AK026155 Homo sapiens cDNA: FLJ22502 fis, clone HRC11383. [AK026155] -1.569367 0.010348959 NM_024680 E2F8 Homo sapiens transcription factor 8 (E2F8), mRNA [NM_024680] -1.5722162 0.034991615 NM_002280 KRT35 Homo sapiens keratin 35 (KRT35), mRNA [NM_002280] -1.5733603 0.039838683 BC010635 BC010635 Homo sapiens, clone IMAGE:3867347, mRNA, partial cds. [BC010635] -1.5771203 0.018264882 AK128746 LOC399744 Homo sapiens cDNA FLJ44672 fis, clone BRACE3006553. [AK128746] -1.577969 0.036308523 NM_005883 APC2 Homo sapiens adenomatosis polyposis coli 2 (APC2), mRNA [NM_005883] -1.5845768 0.047813077 AK092942 AK092942 Homo sapiens cDNA FLJ35623 fis, clone SPLEN2010986. [AK092942] -1.5859078 0.03855025 BE835321 BE835321 BE835321 RC5-FN0022-300600-022-G12 FN0022 Homo sapiens cDNA, mRNA sequence [BE835321] -1.5884693 0.01454741 AK057177 L3MBTL2 Homo sapiens cDNA FLJ32615 fis, clone STOMA2000148. [AK057177] -1.5911092 0.038992953 THC2726026 Q3X600_9ACTN (Q3X600) Adenine deaminase , partial (4%) [THC2726026] -1.5925263 0.020241978 NM_002379 MATN1 Homo sapiens matrilin 1, cartilage matrix protein (MATN1), mRNA [NM_002379] Homo sapiens similar to Williams Beuren syndrome chromosome region 19 (MGC57359), mRNA -1.5946974 0.006299124 NM_001004351 tcag7.1017 [NM 001004351] -1.5990164 0.023042306 NM_000835 GRIN2C Homo sapiens glutamate receptor, ionotropic, N-methyl D-aspartate 2C (GRIN2C), mRNA [NM_000835] -1.602648 0.003184482 AK097080 AK097080 Homo sapiens cDNA FLJ39761 fis, clone SPLEN1000083. [AK097080] -1.6039236 0.025199333 AK027667 AK027667 Homo sapiens cDNA FLJ14761 fis, clone NT2RP3003302. [AK027667] -1.6086218 0.026108403 NM_006998 SCGN Homo sapiens secretagogin, EF-hand calcium binding protein (SCGN), mRNA [NM_006998] Homo sapiens chromosome 20 open reading frame 119, mRNA (cDNA clone IMAGE:4745538), with -1.610897 0.031238537 BC039151 C20orf119 apparent retained intron. [BC039151] -1.6132556 0.018791772 NM_012400 PLA2G2D Homo sapiens phospholipase A2, group IID (PLA2G2D), mRNA [NM_012400] -1.6147109 0.013797627 NM_014475 DHDH Homo sapiens dihydrodiol dehydrogenase (dimeric) (DHDH), mRNA [NM_014475] PREDICTED: Homo sapiens similar to Keratin, type I cytoskeletal 18 (Cytokeratin-18) (CK-18) (Keratin-18) -1.6184499 0.001484091 XR_018959 LOC649928 (K18) (LOC649928), mRNA [XR 018959] -1.6208285 0.027938578 NM_080429 AQP10 Homo sapiens aquaporin 10 (AQP10), mRNA [NM_080429] -1.623709 0.021091195 NM_004278 PIGL Homo sapiens phosphatidylinositol glycan anchor biosynthesis, class L (PIGL), mRNA [NM_004278] -1.6261424 0.024392225 NM_024756 MMRN2 Homo sapiens multimerin 2 (MMRN2), mRNA [NM_024756] -1.6289276 0.025238113 AL512694 AL512694 Homo sapiens mRNA; cDNA DKFZp761J2423 (from clone DKFZp761J2423). [AL512694] -1.6374899 0.019156758 NM_002751 MAPK11 Homo sapiens mitogen-activated protein kinase 11 (MAPK11), mRNA [NM_002751] -1.6383985 0.020315923 NM_018334 LRRN3 Homo sapiens leucine rich repeat neuronal 3 (LRRN3), mRNA [NM_018334] -1.6386155 0.03699745 NM_032601 MCEE Homo sapiens methylmalonyl CoA epimerase (MCEE), mRNA [NM_032601] -1.6470704 0.043753665 THC2693842 -1.6517792 0.033285893 NM_004311 ARL3 Homo sapiens ADP-ribosylation factor-like 3 (ARL3), mRNA [NM_004311] -1.6530238 0.03697487 CR992331 CR992331 CR992331 RZPD no.9016 Homo sapiens cDNA clone RZPDp9016A0141 5', mRNA sequence [CR992331] Homo sapiens Sfi1 homolog, spindle assembly associated (yeast) (SFI1), transcript variant 1, mRNA -1.6566479 0.004073699 NM_001007467 SFI1 [NM 001007467] Homo sapiens Sec61 alpha 2 subunit (S. cerevisiae), mRNA (cDNA clone MGC:32910 IMAGE:4823130), -1.6604842 0.04957019 BC026179 SEC61A2 complete cds. [BC026179] -1.6617463 0.003540027 NM_058177 HDAC9 Homo sapiens 9 (HDAC9), transcript variant 2, mRNA [NM_058177] -1.6724722 5.64E-04 AL049443 AL049443 Homo sapiens mRNA; cDNA DKFZp586N2020 (from clone DKFZp586N2020). [AL049443] -1.6738919 0.021011772 NM_000608 ORM2 Homo sapiens orosomucoid 2 (ORM2), mRNA [NM_000608] -1.6741147 0.036698133 NM_138938 REG3A Homo sapiens regenerating islet-derived 3 alpha (REG3A), transcript variant 2, mRNA [NM_138938] -1.6771233 0.017934827 AK123235 CCDC108 Homo sapiens cDNA FLJ41241 fis, clone BRAMY2032242. [AK123235] -1.6835232 0.01027033 NM_020982 CLDN9 Homo sapiens claudin 9 (CLDN9), mRNA [NM_020982] -1.6915681 0.00257544 NM_018009 TAPBPL Homo sapiens TAP binding protein-like (TAPBPL), mRNA [NM_018009] -1.6925832 0.016499951 NM_001077693 ECSM2 Homo sapiens endothelial cell-specific molecule 2 (ECSM2), mRNA [NM_001077693] -1.6985221 0.02611071 AK022044 AK022044 Homo sapiens cDNA FLJ11982 fis, clone HEMBB1001335. [AK022044] -1.7037092 0.013374112 NM_002256 KISS1 Homo sapiens KiSS-1 metastasis-suppressor (KISS1), mRNA [NM_002256] -1.7039202 0.003556191 NM_001713 BHMT Homo sapiens betaine-homocysteine methyltransferase (BHMT), mRNA [NM_001713] -1.7069341 0.032043822 THC2652700 -1.708097 0.01388497 AL136588 C8orf57 Homo sapiens mRNA; cDNA DKFZp761D112 (from clone DKFZp761D112). [AL136588] -1.7122544 0.030662514 NM_000854 GSTT2 Homo sapiens S-transferase theta 2 (GSTT2), mRNA [NM_000854] -1.7180547 0.04121074 NM_018378 FBXL8 Homo sapiens F-box and leucine-rich repeat protein 8 (FBXL8), mRNA [NM_018378] -1.7182305 0.040762592 NM_002246 KCNK3 Homo sapiens potassium channel, subfamily K, member 3 (KCNK3), mRNA [NM_002246] -1.7182935 4.34E-04 NM_020064 BARHL1 Homo sapiens BarH-like 1 (Drosophila) (BARHL1), mRNA [NM_020064] wp75e09.x1 NCI_CGAP_Brn25 Homo sapiens cDNA clone IMAGE:2467624 3' similar to TR:O75276 -1.7199113 0.015765546 AI937300 AI937300 O75276 PKD1 ;, mRNA sequence [AI937300] -1.7266418 2.22E-04 NM_001080522 KIAA1345 Homo sapiens KIAA1345 protein (KIAA1345), mRNA [NM_001080522] Homo sapiens endothelial differentiation, G-protein-coupled receptor, 6 (EDG6), -1.7277799 0.013578011 NM_003775 EDG6 mRNA [NM 003775] -1.7346959 7.89E-04 NM_018943 TUBA8 Homo sapiens tubulin, alpha 8 (TUBA8), mRNA [NM_018943] -1.7520291 0.006061161 NM_139247 ADCY4 Homo sapiens adenylate cyclase 4 (ADCY4), mRNA [NM_139247] -1.7521939 0.009508186 NM_001459 FLT3LG Homo sapiens fms-related tyrosine kinase 3 ligand (FLT3LG), mRNA [NM_001459] -1.7587633 0.039941035 XM_928321 LOC645277 PREDICTED: Homo sapiens hypothetical LOC645277 (LOC645277), mRNA [XM_928321] -1.784059 0.035924 NM_032293 GARNL3 Homo sapiens GTPase activating Rap/RanGAP domain-like 3 (GARNL3), mRNA [NM_032293] -1.7941551 0.037400715 NM_005588 MEP1A Homo sapiens , alpha (PABA peptide ) (MEP1A), mRNA [NM_005588] -1.7970543 0.047055226 NM_000519 HBD Homo sapiens hemoglobin, delta (HBD), mRNA [NM_000519] myosin XVB pseudogene (MYO15B), misc RNA [Source:RefSeq_dna;Acc:XR_017828] -1.797977 0.013352064 ENST00000293201 [ENST00000293201] -1.8096869 0.04772664 AK124702 AK124702 Homo sapiens cDNA FLJ42712 fis, clone BRAMY3008044. [AK124702] CB853344 UI-CF-FN0-agc-a-02-0-UI.s1 UI-CF-FN0 Homo sapiens cDNA clone UI-CF-FN0-agc-a-02-0-UI -1.8100904 0.007604075 CB853344 CB853344 3', mRNA sequence [CB853344] -1.8206391 0.03422491 NM_152772 TCP11L2 Homo sapiens t-complex 11 (mouse)-like 2 (TCP11L2), mRNA [NM_152772] -1.8249453 0.019964231 THC2694735 AB003177 proteasome subunit p27 {Homo sapiens} (exp=-1; wgp=0; cg=0), partial (9%) [THC2694735] -1.8296162 0.026655825 NM_020809 ARHGAP20 Homo sapiens Rho GTPase activating protein 20 (ARHGAP20), mRNA [NM_020809] -1.8324888 0.009004718 A_32_P80523 -1.8327188 0.02522292 NM_015645 C1QTNF5 Homo sapiens C1q and tumor necrosis factor related protein 5 (C1QTNF5), mRNA [NM_015645] -1.8395492 0.033921644 NM_013397 C6orf49 Homo sapiens chromosome 6 open reading frame 49 (C6orf49), mRNA [NM_013397] -1.8414375 0.04816752 NM_206966 MGC23985 Homo sapiens similar to AVLV472 (MGC23985), mRNA [NM_206966] Immunoglobulin heavy chain V gene segment [Source:IMGT/GENE_DB;Acc:IGHV2-5] -1.8464203 0.028392265 ENST00000390597 [ENST00000390597] -1.8486184 0.012345179 ENST00000372821 Polyadenylate-binding protein 1-like. [Source:Uniprot/SWISSPROT;Acc:Q4VXU2] [ENST00000372821] -1.849938 0.014205175 NM_001711 BGN Homo sapiens biglycan (BGN), mRNA [NM_001711] Homo sapiens transglutaminase 1 (K polypeptide epidermal type I, protein--gamma- -1.8504871 0.027988812 NM_000359 TGM1 glutamyltransferase) (TGM1), mRNA [NM 000359] -1.8527671 0.001814239 NM_138961 ESAM Homo sapiens endothelial cell adhesion molecule (ESAM), mRNA [NM_138961] -1.8664978 0.024645971 NM_005282 GPR4 Homo sapiens G protein-coupled receptor 4 (GPR4), mRNA [NM_005282] -1.8757342 0.017012797 NM_207380 FLJ43339 Homo sapiens FLJ43339 protein (FLJ43339), mRNA [NM_207380] Homo sapiens zinc finger, MYM-type 6, mRNA (cDNA clone MGC:52473 IMAGE:5455214), complete cds. -1.8856467 0.035617575 BC042172 BC042172 [BC042172] Immunoglobulin heavy chain V gene segment [Source:IMGT/GENE_DB;Acc:IGHV3-30] -1.8940513 0.04404913 ENST00000390613 [ENST00000390613] -1.9006382 0.029334862 NM_000160 GCGR Homo sapiens (GCGR), mRNA [NM_000160] -1.9023535 0.02825937 NM_019102 HOXA5 Homo sapiens homeobox A5 (HOXA5), mRNA [NM_019102] -1.9164692 0.019531902 THC2765857 -1.9255208 0.004897974 NM_013989 DIO2 Homo sapiens deiodinase, iodothyronine, type II (DIO2), transcript variant 1, mRNA [NM_013989] -1.9265653 0.01735801 NM_002984 CCL4 Homo sapiens chemokine (C-C motif) ligand 4 (CCL4), transcript variant 1, mRNA [NM_002984] -1.9323832 0.04760095 NM_001005336 DNM1 Homo sapiens dynamin 1 (DNM1), transcript variant 2, mRNA [NM_001005336] Homo sapiens vitamin D (1,25- dihydroxyvitamin D3) receptor (VDR), transcript variant 2, mRNA -1.9338394 0.010469252 NM_001017535 VDR [NM 001017535] -1.9469779 0.03640128 A_24_P332911 -1.9564238 0.049054764 AK097517 LOC283767 Homo sapiens cDNA FLJ40198 fis, clone TESTI2019975, weakly similar to TRICHOHYALIN. [AK097517] -1.9712231 0.004983381 AK026768 DPY19L1P1 Homo sapiens cDNA: FLJ23115 fis, clone LNG07933. [AK026768] Homo sapiens open reading frame 5, mRNA (cDNA clone MGC:97283 IMAGE:7262532), -1.9862763 0.017874118 BC069765 C15orf5 complete cds. [BC069765] -1.9870319 0.0425841 NM_014552 GRHL1 Homo sapiens grainyhead-like 1 (Drosophila) (GRHL1), transcript variant 1, mRNA [NM_014552] Human mRNA for immunoglobulin lambda variable region corresponding to NEW protein of V lambda -1.9990321 0.01502008 X01147 X01147 subgroup I. [X01147] -2.0049317 0.002896668 NM_178332 GNRH2 Homo sapiens gonadotropin-releasing hormone 2 (GNRH2), transcript variant 2, mRNA [NM_178332] -2.0717108 0.038882934 THC2526402 Q504T5_HUMAN (Q504T5) UNC84B protein, partial (12%) [THC2526402] -2.0757077 0.001503597 ENST00000377525 Protein FAM27E1. [Source:Uniprot/SWISSPROT;Acc:Q5T7N7] [ENST00000377525] -2.0802794 0.03572006 NM_024689 CXorf36 Homo sapiens chromosome X open reading frame 36 (CXorf36), mRNA [NM_024689] -2.0963383 0.004578367 U77706 U77706 Human laminin alpha 4 chain (LAMA4*-1) mRNA, complete cds. [U77706] -2.0982625 0.003707181 NM_006757 TNNT3 Homo sapiens troponin T type 3 (skeletal, fast) (TNNT3), transcript variant 2, mRNA [NM_006757] -2.1150525 0.012877065 NM_007078 LDB3 Homo sapiens LIM domain binding 3 (LDB3), transcript variant 1, mRNA [NM_007078] -2.139421 0.012522348 NM_138445 GPR146 Homo sapiens G protein-coupled receptor 146 (GPR146), mRNA [NM_138445] -2.1594949 0.038055617 NM_152394 C3orf44 Homo sapiens open reading frame 44 (C3orf44), mRNA [NM_152394] -2.196152 0.012434772 NM_005840 SPRY3 Homo sapiens sprouty homolog 3 (Drosophila) (SPRY3), mRNA [NM_005840] -2.2158396 0.020498632 NM_000119 EPB42 Homo sapiens erythrocyte membrane protein band 4.2 (EPB42), mRNA [NM_000119] Homo sapiens keratin associated protein 2-4, mRNA (cDNA clone MGC:74790 IMAGE:3907481), complete -2.2768092 0.036612093 BC063625 KRTAP2-4 cds. [BC063625] -2.2991102 0.008151444 BX647344 AVIL Homo sapiens mRNA; cDNA DKFZp779O1812 (from clone DKFZp779O1812). [BX647344] -2.3022435 0.034869015 NM_178571 MGC51025 Homo sapiens hypothetical protein MGC51025 (MGC51025), mRNA [NM_178571] -2.3077645 0.01304492 NM_001558 IL10RA Homo sapiens interleukin 10 receptor, alpha (IL10RA), mRNA [NM_001558] -2.322474 0.004256165 NM_207352 CYP4V2 Homo sapiens cytochrome P450, family 4, subfamily V, polypeptide 2 (CYP4V2), mRNA [NM_207352] -2.3332822 0.004449594 NM_004653 JARID1D Homo sapiens jumonji, AT rich interactive domain 1D (JARID1D), mRNA [NM_004653] -2.3333225 0.013034947 AX721193 AX721193 Sequence 153 from Patent WO0220754. [AX721193] AB065617 seven transmembrane helix receptor {Homo sapiens} (exp=-1; wgp=0; cg=0), partial (4%) -2.4021332 0.038929846 THC2728570 [THC2728570] -2.4074032 0.003019288 NM_024563 C5orf23 Homo sapiens chromosome 5 open reading frame 23 (C5orf23), mRNA [NM_024563] Homo sapiens hypoxia-inducible factor prolyl 4-hydroxylase, mRNA (cDNA clone IMAGE:5017414), partial -2.4188943 0.047220454 BC018731 PH-4 cds. [BC018731] -2.453236 0.01873763 THC2722117 -2.5126126 0.006619151 NM_032153 ZIC4 Homo sapiens Zic family member 4 (ZIC4), mRNA [NM_032153] Homo sapiens C-type lectin domain family 10, member A (CLEC10A), transcript variant 1, mRNA -2.5287108 0.049196266 NM_182906 CLEC10A [NM 182906] -2.5295694 0.04540009 NM_014080 DUOX2 Homo sapiens dual oxidase 2 (DUOX2), mRNA [NM_014080] -2.5782 3.92E-04 BC036938 NF-E4 Homo sapiens, clone IMAGE:5404753, mRNA. [BC036938] -2.6134176 0.017993236 NM_144650 ADHFE1 Homo sapiens alcohol dehydrogenase, iron containing, 1 (ADHFE1), mRNA [NM_144650] -2.6352484 0.013226329 NM_052866 ADAMTSL1 Homo sapiens ADAMTS-like 1 (ADAMTSL1), transcript variant 2, mRNA [NM_052866] -2.6570125 0.010352378 AL832535 LOC157627 Homo sapiens mRNA; cDNA DKFZp547J1816 (from clone DKFZp547J1816). [AL832535] -2.6815948 0.004444331 NM_006237 POU4F1 Homo sapiens POU domain, class 4, transcription factor 1 (POU4F1), mRNA [NM_006237] -2.6974077 0.004424495 NM_000893 KNG1 Homo sapiens kininogen 1 (KNG1), mRNA [NM_000893] -2.7496376 0.026305309 NM_203297 TRIM7 Homo sapiens tripartite motif-containing 7 (TRIM7), transcript variant 2, mRNA [NM_203297] -2.8796086 0.037908882 NM_174896 C1orf162 Homo sapiens chromosome 1 open reading frame 162 (C1orf162), mRNA [NM_174896] 602039925F2 NCI_CGAP_Brn67 Homo sapiens cDNA clone IMAGE:4177446 5', mRNA sequence -2.9251754 0.003563132 BF527031 BF527031 [BF527031] -2.992101 0.039273612 NM_020851 ISLR2 Homo sapiens immunoglobulin superfamily containing leucine-rich repeat 2 (ISLR2), mRNA [NM_020851] -3.002287 5.58E-04 NM_206827 RASL11A Homo sapiens RAS-like, family 11, member A (RASL11A), mRNA [NM_206827] -3.002531 0.00620886 NR_003260 C15orf51 Homo sapiens chromosome 15 open reading frame 51 (C15orf51) on chromosome 15 [NR_003260] -3.0412552 0.003332714 AW994037 AW994037 AW994037 RC3-BN0036-090200-011-f03 BN0036 Homo sapiens cDNA, mRNA sequence [AW994037] -3.069127 0.013844444 NM_016585 THEG Homo sapiens Theg homolog (mouse) (THEG), transcript variant 1, mRNA [NM_016585] Homo sapiens protein tyrosine phosphatase, receptor type, O (PTPRO), transcript variant 1, mRNA -3.1709142 0.01810251 NM_030667 PTPRO [NM 030667] -3.3513951 0.032414507 NM_004895 NLRP3 Homo sapiens NLR family, pyrin domain containing 3 (NLRP3), transcript variant 1, mRNA [NM_004895] -3.4961028 0.012849323 THC2617409 Q6F0E0_MESFL (Q6F0E0) Recombination protein, partial (8%) [THC2617409] -3.541798 0.026638336 NP389850 GB|AF399571.1|AAK95056.1 olfactory receptor [Homo sapiens] [NP389850] -3.7207243 0.036655493 NM_014143 CD274 Homo sapiens CD274 molecule (CD274), mRNA [NM_014143] -3.937025 0.010228786 NM_021013 KRT34 Homo sapiens keratin 34 (KRT34), mRNA [NM_021013] -3.9779854 0.011320006 BC089451 BC089451 Homo sapiens cDNA clone IMAGE:30554612. [BC089451] W60781 zd26f05.r1 Soares_fetal_heart_NbHH19W Homo sapiens cDNA clone IMAGE:341793 5' similar to -5.099088 0.03372998 W60781 W60781 gb:J02874 FATTY ACID-BINDING PROTEIN, ADIPOCYTE (HUMAN);, mRNA sequence [W60781] -5.221845 0.003079117 NM_003965 CCRL2 Homo sapiens chemokine (C-C motif) receptor-like 2 (CCRL2), mRNA [NM_003965] Table S5. Ingenuity Pathway Analysis: Canonical Pathways, 0.4 vs. 0 Gy irradiation

No overlap -Log(P -value) Ratio Downregulated No change Upregulated Molecules Canonical Pathways with dataset PLCB2, JUN, CCL4, CAMK2D, Chemokine Signaling 3.12E00 9.09E-02 3/77 (4%) 0/77 (0%) 4/77 (5%) 70/77 (91%) RHOA, MAPK13, MAPK11 VEGFA, JUN, MMP16, HIF1α Signaling 2.43E00 6.67E-02 3/105 (3%) 0/105 (0%) 4/105 (4%) 98/105 (93%) MAPK13, MAPK11, SLC2A3, P4HTM DNM1, PLCB2, JUN, CAMK2D, GNRH Signaling 2.42E00 5.59E-02 5/143 (3%) 0/143 (0%) 3/143 (2%) 135/143 (94%) ADCY4, GNRH2, MAPK13, MAPK11 S1PR4, CASP6, PLCB2, RHOT1, Sphingosine-1-phosphate Signaling 2.31E00 6.19E-02 3/113 (3%) 0/113 (0%) 4/113 (4%) 106/113 (94%) ADCY4, RHOA, GNA13 CASP6, PLCB2, JUN, PLA2G2D, Endothelin-1 Signaling 2.17E00 4.84E-02 4/186 (2%) 0/186 (0%) 5/186 (3%) 177/186 (95%) ADCY4, EDNRA, MAPK13, GNA13, MAPK11 JUN, RHOT1, MYST4, RHOA, HMGB1 Signaling 1.92E00 6.12E-02 1/98 (1%) 0/98 (0%) 5/98 (5%) 92/98 (94%) MAPK13, MAPK11 PLCB2, JUN, RHOT1, RHOA, Cholecystokinin/Gastrin-mediated Signaling 1.82E00 5.77E-02 1/104 (1%) 0/104 (0%) 5/104 (5%) 98/104 (94%) EPHA4, GNA13 PRKDC, PLCB2, ADCY4, RALB, MAPK13, MAPK11, Molecular Mechanisms of Cancer 1.7E00 3.49E-02 3/372 (1%) 0/372 (0%) 10/372 (3%) 359/372 (97%) CASP6, JUN, CAMK2D, RHOT1, RHOA, GNA13, HIPK2 PLCB2, PLA2G2D, RHOA, CCR3 Signaling in Eosinophils 1.59E00 4.92E-02 4/122 (3%) 0/122 (0%) 2/122 (2%) 116/122 (95%) JMJD7-PLA2G4B, MAPK13, MAPK11 JUN, IL10RA, MAPK13, IL-10 Signaling 1.48E00 5.71E-02 2/70 (3%) 0/70 (0%) 2/70 (3%) 66/70 (94%) MAPK11 PRKDC, CASP6, JUN, THBS1, p53 Signaling 1.47E00 5.62E-02 1/89 (1%) 0/89 (0%) 4/89 (4%) 84/89 (94%) HIPK2 PLCB2, CAMK2D, RHOT1, Thrombin Signaling 1.44E00 3.92E-02 3/204 (1%) 0/204 (0%) 5/204 (2%) 196/204 (96%) ADCY4, RHOA, MAPK13, GNA13, MAPK11 JUN, CRB3, MPP5, RHOA, Tight Junction Signaling 1.43E00 4.27E-02 1/164 (1%) 0/164 (0%) 6/164 (4%) 157/164 (96%) SAFB, CLDN9, CLDN7 Parkinson's Signaling 1.43E00 1.18E-01 1/17 (6%) 0/17 (0%) 1/17 (6%) 15/17 (88%) MAPK13, MAPK11 PLCB2, JUN, RHOT1, ADCY4, Cardiac Hypertrophy Signaling 1.42E00 3.7E-02 4/243 (2%) 0/243 (0%) 5/243 (2%) 234/243 (96%) RHOA, CACNA1C, MAPK13, GNA13, MAPK11 CCR5 Signaling in Macrophages 1.41E00 4.4E-02 2/91 (2%) 0/91 (0%) 2/91 (2%) 87/91 (96%) JUN, CCL4, MAPK13, MAPK11 April Mediated Signaling 1.39E00 7.14E-02 1/42 (2%) 0/42 (0%) 2/42 (5%) 39/42 (93%) JUN, MAPK13, MAPK11 ENTPD4, MPP5, XDH, ADCY4, Purine Metabolism 1.34E00 2.5E-02 1/440 (0%) 0/440 (0%) 10/440 (2%) 429/440 (98%) DLG2, PAPD5, PDE5A, RUVBL1, HSPD1, ATP5G3, JUN, PLA2G2D, JMJD7- MIF Regulation of Innate Immunity 1.34E00 6.25E-02 2/48 (4%) 0/48 (0%) 1/48 (2%) 45/48 (94%) PLA2G4B B Cell Activating Factor Signaling 1.34E00 6.82E-02 1/44 (2%) 0/44 (0%) 2/44 (5%) 41/44 (93%) JUN, MAPK13, MAPK11 Nitric Oxide Signaling in the Cardiovascular VEGFA, KNG1 (includes 1.25E00 4.35E-02 2/92 (2%) 0/92 (0%) 2/92 (2%) 88/92 (96%) System EG:3827), HSP90AB1, CACNA1C Role of Oct4 in Mammalian Embryonic Stem 1.18E00 6.67E-02 0/45 (0%) 0/45 (0%) 3/45 (7%) 42/45 (93%) CASP6, BMI1, PPP1R8 Cell Pluripotency MMP16, EZR, RHOA, CLDN9, Leukocyte Extravasation Signaling 1.13E00 3.59E-02 3/195 (2%) 0/195 (0%) 4/195 (2%) 188/195 (96%) MAPK13, CLDN7, MAPK11 VEGFA, JUN, ADCY4, Corticotropin Releasing Hormone Signaling 1.12E00 3.68E-02 2/136 (1%) 0/136 (0%) 3/136 (2%) 131/136 (96%) MAPK13, MAPK11 Toll-like Receptor Signaling 1.12E00 5.56E-02 1/54 (2%) 0/54 (0%) 2/54 (4%) 51/54 (94%) JUN, MAPK13, MAPK11 ACTR2, JUN, MAPK13, Cdc42 Signaling 1.08E00 3.79E-02 1/132 (1%) 0/132 (0%) 4/132 (3%) 127/132 (96%) MAPK11, CLIP1 ATM Signaling 1.06E00 5.77E-02 1/52 (2%) 0/52 (0%) 2/52 (4%) 49/52 (94%) JUN, MAPK13, MAPK11 PLCB2, JUN, RHOT1, ADCY4, CXCR4 Signaling 1.05E00 3.57E-02 2/168 (1%) 0/168 (0%) 4/168 (2%) 162/168 (96%) RHOA, GNA13 VEGFA, SIAH1, APPL1, JUN, Colorectal Cancer Metastasis Signaling 1.05E00 3.24E-02 2/247 (1%) 0/247 (0%) 6/247 (2%) 239/247 (97%) RHOT1, MMP16, ADCY4, RHOA

Regulation of Actin-based Motility by Rho 1.01E00 4.3E-02 1/93 (1%) 0/93 (0%) 3/93 (3%) 89/93 (96%) ACTR2, RHOT1, RHOA, WASF1 IL-22 Signaling 1E00 7.41E-02 1/27 (4%) 0/27 (0%) 1/27 (4%) 25/27 (93%) MAPK13, MAPK11 Metabolism of Xenobiotics by Cytochrome ALDH3B2 (includes EG:222), 9.91E-01 1.9E-02 3/210 (1%) 0/210 (0%) 1/210 (0%) 206/210 (98%) P450 DHDH, GSTT2, ADHFE1 Metabolism 9.22E-01 2.5E-02 1/80 (1%) 0/80 (0%) 1/80 (1%) 78/80 (98%) BHMT, CA1 (includes EG:759) Citrate Cycle 8.97E-01 3.39E-02 0/59 (0%) 0/59 (0%) 2/59 (3%) 57/59 (97%) SUCLA2, ATP5G3 PLA2G2D, JMJD7-PLA2G4B, p38 MAPK Signaling 8.87E-01 4.21E-02 3/95 (3%) 0/95 (0%) 1/95 (1%) 91/95 (96%) MAPK13, MAPK11 CD40 Signaling 8.82E-01 4.35E-02 1/69 (1%) 0/69 (0%) 2/69 (3%) 66/69 (96%) JUN, MAPK13, MAPK11 PLA2G2D, JMJD7-PLA2G4B, Fc Epsilon RI Signaling 8.75E-01 3.81E-02 3/105 (3%) 0/105 (0%) 1/105 (1%) 101/105 (96%) MAPK13, MAPK11 CAMK2D, TPM3, GRIN2C, Calcium Signaling 8.7E-01 2.91E-02 3/206 (1%) 0/206 (0%) 3/206 (1%) 200/206 (97%) TNNT3, HDAC9 (includes EG:9734), TPM4 ACTR2, APC2, EZR, RHOA, Actin Signaling 8.7E-01 2.95E-02 3/237 (1%) 0/237 (0%) 4/237 (2%) 230/237 (97%) MYLK2, WASF1, GNA13 VEGFA, ACTR2, GRIN2C, Ephrin Receptor Signaling 8.53E-01 3.02E-02 1/199 (1%) 0/199 (0%) 5/199 (3%) 193/199 (97%) RHOA, EPHA4, GNA13 Hypoxia Signaling in the Cardiovascular 8.51E-01 4.29E-02 0/70 (0%) 0/70 (0%) 3/70 (4%) 67/70 (96%) VEGFA, JUN, HSP90AB1 System IL-12 Signaling and Production in ALOX15, JUN, MAPK13, 8.07E-01 3.03E-02 1/132 (1%) 0/132 (0%) 3/132 (2%) 128/132 (97%) Macrophages MAPK11 FLT3 Signaling in Hematopoietic Progenitor 7.95E-01 4.11E-02 2/73 (3%) 0/73 (0%) 1/73 (1%) 70/73 (96%) MAPK13, MAPK11, FLT3LG Cells JUN, ADCY4, MAPK13, Renin-Angiotensin Signaling 7.75E-01 3.33E-02 2/120 (2%) 0/120 (0%) 2/120 (2%) 116/120 (97%) MAPK11 PLCB2, CAMK2D, GRIN2C, Synaptic Long Term Potentiation 7.65E-01 3.48E-02 3/115 (3%) 0/115 (0%) 1/115 (1%) 111/115 (97%) CACNA1C LPS-stimulated MAPK Signaling 7.43E-01 3.75E-02 1/80 (1%) 0/80 (0%) 2/80 (3%) 77/80 (96%) JUN, MAPK13, MAPK11 IL-17 Signaling 7.43E-01 4.11E-02 1/73 (1%) 0/73 (0%) 2/73 (3%) 70/73 (96%) JUN, MAPK13, MAPK11 Melatonin Signaling 7.43E-01 3.85E-02 2/78 (3%) 0/78 (0%) 1/78 (1%) 75/78 (96%) PLCB2, CAMK2D, GNRH2 BMP signaling pathway 7.07E-01 3.75E-02 1/80 (1%) 0/80 (0%) 2/80 (3%) 77/80 (96%) JUN, MAPK13, MAPK11 Ceramide Signaling 6.96E-01 3.57E-02 1/84 (1%) 0/84 (0%) 2/84 (2%) 81/84 (96%) S1PR4, JUN, KSR1 Production of Nitric Oxide and Reactive JUN, RHOT1, RHOA, MAPK13, 6.94E-01 2.69E-02 1/186 (1%) 0/186 (0%) 4/186 (2%) 181/186 (97%) in Macrophages MAPK11 ALDH3B2 (includes EG:222), Inositol Metabolism 6.84E-01 3.06E-02 2/98 (2%) 0/98 (0%) 1/98 (1%) 95/98 (97%) DHDH, ADHFE1 VEGFA, JUN, ADCY4, RAR Activation 6.35E-01 2.81E-02 2/178 (1%) 0/178 (0%) 3/178 (2%) 173/178 (97%) MAPK13, MAPK11 TR/RXR Activation 6.31E-01 3.19E-02 1/94 (1%) 0/94 (0%) 2/94 (2%) 91/94 (97%) NCOA4, DIO3, DIO2 Relaxin Signaling 6.28E-01 2.7E-02 1/148 (1%) 0/148 (0%) 3/148 (2%) 144/148 (97%) VEGFA, JUN, ADCY4, GNA13 ALDH3B2 (includes EG:222), Xenobiotic Metabolism Signaling 6.25E-01 2.38E-02 2/294 (1%) 0/294 (0%) 5/294 (2%) 287/294 (98%) CAMK2D, HSP90AB1, GSTT2, NDST4, MAPK13, MAPK11 Nucleotide Sugars Metabolism 6.25E-01 1.35E-02 0/74 (0%) 0/74 (0%) 1/74 (1%) 73/74 (99%) ALOX15 Phospholipid Degradation 6.11E-01 2.83E-02 2/106 (2%) 0/106 (0%) 1/106 (1%) 103/106 (97%) PLCB2, PPAP2A, PLA2G2D GABA Receptor Signaling 6.11E-01 3.64E-02 1/55 (2%) 0/55 (0%) 1/55 (2%) 53/55 (96%) DNM1, GABRA3 VEGFA, PLCB2, RHOT1, IL-8 Signaling 6.01E-01 2.67E-02 1/187 (1%) 0/187 (0%) 4/187 (2%) 182/187 (97%) RHOA, GNA13 Hepatic Fibrosis / Hepatic Stellate Cell VEGFA, IL10RA, LAMA1, 5.96E-01 2.96E-02 1/135 (1%) 0/135 (0%) 3/135 (2%) 131/135 (97%) Activation EDNRA PLCB2, PPAP2A, PLA2G2D, Glycerophospholipid Metabolism 5.88E-01 2.07E-02 3/193 (2%) 0/193 (0%) 1/193 (1%) 189/193 (98%) ETNK1 Bladder Cancer Signaling 5.73E-01 3.23E-02 2/93 (2%) 0/93 (0%) 1/93 (1%) 90/93 (97%) VEGFA, THBS1, MMP16 IL-6 Signaling 5.64E-01 3.16E-02 1/95 (1%) 0/95 (0%) 2/95 (2%) 92/95 (97%) JUN, MAPK13, MAPK11 PLCB2, ADCY4, CACNA1C, Cellular Effects of Sildenafil (Viagra) 5.59E-01 2.65E-02 3/151 (2%) 0/151 (0%) 1/151 (1%) 147/151 (97%) PDE5A Amyotrophic Lateral Sclerosis Signaling 5.47E-01 2.68E-02 2/112 (2%) 0/112 (0%) 1/112 (1%) 109/112 (97%) VEGFA, GRIN2C, CACNA1C Amyloid Processing 5.36E-01 3.57E-02 1/56 (2%) 0/56 (0%) 1/56 (2%) 54/56 (96%) MAPK13, MAPK11 ALDH3B2 (includes EG:222), Aryl Hydrocarbon Receptor Signaling 5.31E-01 2.55E-02 1/157 (1%) 0/157 (0%) 3/157 (2%) 153/157 (97%) JUN, HSP90AB1, GSTT2 Folate Biosynthesis 5.25E-01 1.25E-02 0/80 (0%) 0/80 (0%) 1/80 (1%) 79/80 (99%) GCH1 PLCB2, PLA2G2D, ADCY4, Synaptic Long Term Depression 5.17E-01 2.44E-02 3/164 (2%) 0/164 (0%) 1/164 (1%) 160/164 (98%) GNA13 Semaphorin Signaling in Neurons 5.03E-01 3.64E-02 0/55 (0%) 0/55 (0%) 2/55 (4%) 53/55 (96%) RHOT1, RHOA N-Glycan Biosynthesis 5.03E-01 2.15E-02 0/93 (0%) 0/93 (0%) 2/93 (2%) 91/93 (98%) MAGT1, MAN1A2 Neuropathic Pain Signaling In Dorsal Horn 4.98E-01 2.88E-02 2/104 (2%) 0/104 (0%) 1/104 (1%) 101/104 (97%) PLCB2, CAMK2D, GRIN2C Neurons Glutamate Receptor Signaling 4.93E-01 2.86E-02 1/70 (1%) 0/70 (0%) 1/70 (1%) 68/70 (97%) GRIN2C, SLC1A1 ALDH3B2 (includes EG:222), LPS/IL-1 Mediated Inhibition of RXR Function 4.92E-01 2.44E-02 1/205 (0%) 0/205 (0%) 4/205 (2%) 200/205 (98%) JUN, GSTT2, NDST4, ABCC4 Maturity Onset Diabetes of Young (MODY) 4.85E-01 3.23E-02 1/31 (3%) 0/31 (0%) 0/31 (0%) 30/31 (97%) CACNA1C Signaling JUN, CAMK2D, MAPK13, B Cell Receptor Signaling 4.85E-01 2.58E-02 1/155 (1%) 0/155 (0%) 3/155 (2%) 151/155 (97%) MAPK11 Type I Diabetes Mellitus Signaling 4.75E-01 2.63E-02 1/114 (1%) 0/114 (0%) 2/114 (2%) 111/114 (97%) MAPK13, HSPD1, MAPK11 DNA Methylation and Transcriptional 4.67E-01 4.35E-02 0/23 (0%) 0/23 (0%) 1/23 (4%) 22/23 (96%) RBBP4 Repression Signaling Glutathione Metabolism 4.63E-01 2.04E-02 1/98 (1%) 0/98 (0%) 1/98 (1%) 96/98 (98%) GSTT2, ATP5G3 ACTR2, RHOT1, RHOA, Integrin Signaling 4.6E-01 2.46E-02 1/203 (0%) 0/203 (0%) 4/203 (2%) 198/203 (98%) MYLK2, RALB IL-15 Signaling 4.54E-01 2.99E-02 1/67 (1%) 0/67 (0%) 1/67 (1%) 65/67 (97%) MAPK13, MAPK11 GM-CSF Signaling 4.44E-01 2.99E-02 1/67 (1%) 0/67 (0%) 1/67 (1%) 65/67 (97%) CAMK2D, RUNX1 Eicosanoid Signaling 4.36E-01 2.38E-02 1/84 (1%) 0/84 (0%) 1/84 (1%) 82/84 (98%) ALOX15, PLA2G2D Cytotoxic T Lymphocyte-mediated Apoptosis of 4.34E-01 3.23E-02 0/31 (0%) 0/31 (0%) 1/31 (3%) 30/31 (97%) CASP6 Target Cells Pantothenate and CoA Biosynthesis 4.34E-01 1.56E-02 0/64 (0%) 0/64 (0%) 1/64 (2%) 63/64 (98%) PANK1 14-3-3-mediated Signaling 4.33E-01 2.63E-02 2/114 (2%) 0/114 (0%) 1/114 (1%) 111/114 (97%) PLCB2, JUN, TUBA8 Pyrimidine Metabolism 4.22E-01 1.72E-02 0/232 (0%) 0/232 (0%) 4/232 (2%) 228/232 (98%) ENTPD4, PAPD5, UNG, POLE Propanoate Metabolism 4.18E-01 1.54E-02 1/130 (1%) 0/130 (0%) 1/130 (1%) 128/130 (98%) SUCLA2, MCEE PLCB2, JUN, HSP90AB1, PPARα/RXRα Activation 4.16E-01 2.17E-02 2/184 (1%) 0/184 (0%) 2/184 (1%) 180/184 (98%) ADCY4 Linoleic Acid Metabolism 4.1E-01 1.61E-02 1/124 (1%) 0/124 (0%) 1/124 (1%) 122/124 (98%) ALOX15, PLA2G2D Glycosphingolipid Biosynthesis - Globoseries 3.91E-01 2.17E-02 0/46 (0%) 0/46 (0%) 1/46 (2%) 45/46 (98%) B3GALNT1 Gα12/13 Signaling 3.9E-01 2.44E-02 0/123 (0%) 0/123 (0%) 3/123 (2%) 120/123 (98%) JUN, RHOA, GNA13 DNM1, CASP6, PLCB2, JUN, Huntington's Disease Signaling 3.89E-01 2.12E-02 3/236 (1%) 0/236 (0%) 2/236 (1%) 231/236 (98%) HDAC9 (includes EG:9734) Renal Cell Carcinoma Signaling 3.86E-01 2.74E-02 0/73 (0%) 0/73 (0%) 2/73 (3%) 71/73 (97%) VEGFA, JUN Androgen Signaling 3.84E-01 2.07E-02 0/145 (0%) 0/145 (0%) 3/145 (2%) 142/145 (98%) JUN, NCOA4, GNA13 ALDH3B2 (includes EG:222), Tyrosine Metabolism 3.79E-01 9.9E-03 1/202 (0%) 0/202 (0%) 1/202 (0%) 200/202 (99%) ADHFE1 IL-15 Production 3.78E-01 3.23E-02 0/31 (0%) 0/31 (0%) 1/31 (3%) 30/31 (97%) TWF1 Acute Myeloid Leukemia Signaling 3.72E-01 2.56E-02 2/78 (3%) 0/78 (0%) 0/78 (0%) 76/78 (97%) RUNX1, FLT3LG Glycine, Serine and Threonine Metabolism 3.72E-01 1.33E-02 2/150 (1%) 0/150 (0%) 0/150 (0%) 148/150 (99%) PLCB2, BHMT PLCB2, CAMK2D, ADCY4, CREB Signaling in Neurons 3.71E-01 2.06E-02 2/194 (1%) 0/194 (0%) 2/194 (1%) 190/194 (98%) GNA13 Acute Phase Response Signaling 3.57E-01 2.26E-02 2/177 (1%) 0/177 (0%) 2/177 (1%) 173/177 (98%) ORM2, JUN, MAPK13, MAPK11 Cardiac β-adrenergic Signaling 3.56E-01 2.14E-02 2/140 (1%) 0/140 (0%) 1/140 (1%) 137/140 (98%) AKAP13, ADCY4, CACNA1C Signaling 3.44E-01 2.2E-02 1/91 (1%) 0/91 (0%) 1/91 (1%) 89/91 (98%) GCH1, ADCY4 N-Glycan Degradation 3.43E-01 3.12E-02 0/32 (0%) 0/32 (0%) 1/32 (3%) 31/32 (97%) MAN1A2 G Protein Signaling Mediated by Tubby 3.32E-01 2.44E-02 1/41 (2%) 0/41 (0%) 0/41 (0%) 40/41 (98%) PLCB2 ILK Signaling 3.31E-01 2.15E-02 0/186 (0%) 0/186 (0%) 4/186 (2%) 182/186 (98%) VEGFA, JUN, RHOT1, RHOA Circadian Rhythm Signaling 3.22E-01 2.86E-02 1/35 (3%) 0/35 (0%) 0/35 (0%) 34/35 (97%) GRIN2C 4-1BB Signaling in T Lymphocytes 3.22E-01 2.78E-02 0/36 (0%) 0/36 (0%) 1/36 (3%) 35/36 (97%) JUN Serotonin Receptor Signaling 3.12E-01 2.17E-02 0/46 (0%) 0/46 (0%) 1/46 (2%) 45/46 (98%) GCH1 TGF-β Signaling 3.12E-01 2.33E-02 1/86 (1%) 0/86 (0%) 1/86 (1%) 84/86 (98%) JUN, VDR FGF Signaling 3.07E-01 2.27E-02 1/88 (1%) 0/88 (0%) 1/88 (1%) 86/88 (98%) MAPK13, MAPK11 Hepatic Cholestasis 3.06E-01 1.82E-02 2/165 (1%) 0/165 (0%) 1/165 (1%) 162/165 (98%) JUN, GCGR, ADCY4 Metabolism 2.94E-01 9.17E-03 0/109 (0%) 0/109 (0%) 1/109 (1%) 108/109 (99%) ALDH3B2 (includes EG:222) PPAR Signaling 2.9E-01 1.98E-02 0/101 (0%) 0/101 (0%) 2/101 (2%) 99/101 (98%) JUN, HSP90AB1 Glycosaminoglycan Degradation 2.86E-01 1.39E-02 0/72 (0%) 0/72 (0%) 1/72 (1%) 71/72 (99%) ALOX15 Coagulation System 2.86E-01 2.7E-02 1/37 (3%) 0/37 (0%) 0/37 (0%) 36/37 (97%) KNG1 (includes EG:3827) T Helper Cell Differentiation 2.86E-01 2.44E-02 1/41 (2%) 0/41 (0%) 0/41 (0%) 40/41 (98%) IL10RA (DHA) Signaling 2.86E-01 2.22E-02 0/45 (0%) 0/45 (0%) 1/45 (2%) 44/45 (98%) ALOX15 Cell Cycle Regulation by BTG Family Proteins 2.86E-01 2.78E-02 0/36 (0%) 0/36 (0%) 1/36 (3%) 35/36 (97%) CNOT7 Nucleotide Excision Repair Pathway 2.86E-01 2.86E-02 0/35 (0%) 0/35 (0%) 1/35 (3%) 34/35 (97%) RAD23B mTOR Signaling 2.8E-01 1.92E-02 0/156 (0%) 0/156 (0%) 3/156 (2%) 153/156 (98%) VEGFA, RHOT1, RHOA Virus Entry via Endocytic Pathways 2.79E-01 2.08E-02 1/96 (1%) 0/96 (0%) 1/96 (1%) 94/96 (98%) DNM1, CXADR SAPK/JNK Signaling 2.79E-01 2.04E-02 0/98 (0%) 0/98 (0%) 2/98 (2%) 96/98 (98%) JUN, GNA13 Glutamate Metabolism 2.69E-01 1.28E-02 1/78 (1%) 0/78 (0%) 0/78 (0%) 77/78 (99%) NADSYN1 ALDH3B2 (includes EG:222), Glycolysis/Gluconeogenesis 2.64E-01 1.39E-02 1/144 (1%) 0/144 (0%) 1/144 (1%) 142/144 (99%) ADHFE1 Retinoic acid Mediated Apoptosis Signaling 2.62E-01 2.27E-02 0/44 (0%) 0/44 (0%) 1/44 (2%) 43/44 (98%) PARP14 Mechanisms of Viral Exit from Host Cells 2.54E-01 2.27E-02 1/44 (2%) 0/44 (0%) 0/44 (0%) 43/44 (98%) VPS24 Cell Cycle: G2/M DNA Damage Checkpoint 2.54E-01 2.33E-02 0/43 (0%) 0/43 (0%) 1/43 (2%) 42/43 (98%) PRKDC Regulation CDK5 Signaling 2.54E-01 2.13E-02 1/94 (1%) 0/94 (0%) 1/94 (1%) 92/94 (98%) ADCY4, LAMA1 KRT35, JUN, HSP90AB1, Glucocorticoid Receptor Signaling 2.51E-01 1.79E-02 2/280 (1%) 0/280 (0%) 3/280 (1%) 275/280 (98%) MAPK13, MAPK11 Fcγ Receptor-mediated Phagocytosis in 2.5E-01 1.92E-02 0/104 (0%) 0/104 (0%) 2/104 (2%) 102/104 (98%) ACTR2, EZR Macrophages and Monocytes Glioma Signaling 2.36E-01 1.79E-02 0/112 (0%) 0/112 (0%) 2/112 (2%) 110/112 (98%) CAMK2D, IGF2R Glycerolipid Metabolism 2.36E-01 1.28E-02 1/156 (1%) 0/156 (0%) 1/156 (1%) 154/156 (99%) PPAP2A, ADHFE1 Bile Acid Biosynthesis 2.21E-01 1E-02 1/100 (1%) 0/100 (0%) 0/100 (0%) 99/100 (99%) ADHFE1 Chondroitin Sulfate Biosynthesis 2.15E-01 1.49E-02 0/67 (0%) 0/67 (0%) 1/67 (1%) 66/67 (99%) NDST4 EGF Signaling 2.15E-01 1.92E-02 0/52 (0%) 0/52 (0%) 1/52 (2%) 51/52 (98%) JUN Keratan Sulfate Biosynthesis 2.1E-01 1.82E-02 0/55 (0%) 0/55 (0%) 1/55 (2%) 54/55 (98%) NDST4 Cysteine Metabolism 2.1E-01 1.11E-02 0/90 (0%) 0/90 (0%) 1/90 (1%) 89/90 (99%) NDST4 Nitrogen Metabolism 2.04E-01 7.46E-03 0/134 (0%) 0/134 (0%) 1/134 (1%) 133/134 (99%) CA1 (includes EG:759) Table S6. Ingenuity Pathway Analysis: Functions, 0.4 vs. 0 Gy irradiation Functions P -value Molecules

FCAR, BARHL1, XDH, MAPK13, DICER1, BRCC3, DYRK3, PDCD7, VEGFA, CAMK2D, BMI1, PTPRO, GRIN2C, EZR, SMG1, CD274, GNA13, HIPK2, UNG, HUWE1, THBS1, MT1X, POU4F1, RALB, CACNA1C, WASF1, SLC1A1, BCAP29, CDCA2, AKAP13, KNG1 (includes EG:3827), TGM1, CCL4, RHOA, RUNX1, Cell Death 6.45E-05-2.99E-02 ABCC4, RBBP4, SIAH1, KCNK3, AKTIP, HDAC9 (includes EG:9734), BECN1, MAPK11, SLC2A3, KSR1, MTMR6, APPL1, ROR2, CASP6, SERPINB9, JUN, HSP90AB1, RHOT1, PPP1R2, HOXA5, RRN3, NCOA4, VDR, GHRL, RAD23B, PRKDC, ALOX15, NLRP3, PPP1R8, BGN, ATRX, DLX2, HSPD1, IGF2R, FLT3LG, UACA, DNM1, CEACAM1, PPAP2A, COX11, TPM3

BARHL1, FMR1, DICER1, MAPK13, BRCC3, POLE, VEGFA, BMI1, CAMK2D, UBXN4, GRIN2C, LAMA1, CD274, GNA13, HIPK2, UNG, HUWE1, MAGT1, C6ORF204, POU4F1, MYST4, CACNA1C, ALAD, SLC1A1, LARP4, NDST4, DIO3, Neurological Disease 6.45E-05-3.01E-02 AKAP13, KNG1 (includes EG:3827), CCL4, TGM1, RHOA, RUNX1, ABCC4, SIAH1, KCNK3, HDAC9 (includes EG:9734), CDKAL1, BECN1, MAPK11, SLC2A3, KSR1, CASP6, JUN, TUBA8, VDR, GABRA3, ALOX15, PRKDC, BGN, ATRX, HSPD1, DLX2, TCP11L2, EDNRA, PDE5A, RTN3

GCGR, TWF1, XDH, DLG2, NPEPPS, MAPK13, DYRK3, VEGFA, BMI1, PTPRO, EZR, CD274, SMG1, GNA13, HIPK2, UNG, SLC26A2, MT1X, POU4F1, RALB, CACNA1C, AKAP13, TGM1, CNOT7, RUNX1, KDM5A, CLIP1, SIAH1, RAB28, EPHA4, RUVBL1, MED28, ARL4D, BECN1, KSR1, ALKBH8, MTMR6, CASP6, C9ORF86, JUN, TUBA8, HSP90AB1, HOXA5, KISS1, VDR, GABRA3, PRKDC, ALOX15, GRTP1, PPP1R8, TOB1, FLT3LG, IGF2R, CEACAM1, RAD54B, CXADR, Cancer 9.66E-05-3.25E-02 SMEK1, EHBP1, RYK, MRPS23, DICER1, CSPP1, POLE, CAMK2D, GPR4, GRIN2C, TNNT3, HBD, HUWE1, GCH1, THBS1, SLC1A1, ALAD, WASF1, CDCA2, PANK1, KNG1 (includes EG:3827), RHOA, ABCC4, ZNF552, RBBP4, KCNK3, BHMT, HDAC9 (includes EG:9734), MAPK11, SLC2A3, ROR2, SERPINB9, HSP90B1, ZNF24 (includes EG:7572), GPR177, NCOA4, GBP2, GHRL, RAD23B, NLRP3, ETFA, BGN, ATRX, RAB8A, HSPD1, DNM1, KRT35, PPAP2A, LAMA4, PDE5A, EDNRA, MEP1A, CLEC10A

Endocrine System Development and Function 1.66E-04-2.06E-02 DUOX2, KISS1, NCOA4, VDR, DIO2, DIO3 SIAH1, ENAH, LDB3, CRB3, XDH, FMR1, MAPK11, KSR1, VEGFA, JUN, EZR, RRN3, KISS1, GNA13, GHRL, ALOX15, THBS1, POU4F1, WASF1, RAB8A, Cellular Assembly and Organization 3.61E-04-2.78E-02 DNM1, KNG1 (includes EG:3827), AKAP13, TPM3, MPP5, LAMA4, RHOA, EDNRA, CXADR, RYK, RBBP4 ALOX15, ENAH, PRKDC, THBS1, WASF1, BECN1, MAPK11, VEGFA, AKAP13, Cellular Function and Maintenance 3.9E-04-2.85E-02 KNG1 (includes EG:3827), CCL4, JUN, TPM3, RHOA, SAFB, GNA13, VDR, GHRL Protein Synthesis 3.9E-04-3.9E-04 ALOX15, ENAH, RHOA, WASF1, MAPK11, GHRL SIAH1, FCAR, LDB3, DICER1, KSR1, VEGFA, JUN, EZR, LAMA1, AMBN, VDR, GNA13, GHRL, THBS1, POU4F1, TOB1, CACNA1C, WASF1, HSPD1, IGF2R, Cell Morphology 4.52E-04-2.85E-02 AVIL, DNM1, AKAP13, KNG1 (includes EG:3827), CCL4, TPM3, EPB42, LAMA4, RHOA, EDNRA, CDC42SE2, CXADR, RBBP4, CLIP1, RYK MGA, FMR1, ZC3HAV1, AKAP13, KNG1 (includes EG:3827), JUN, GPR4, RHOA, Gene Expression 9.71E-04-2.06E-02 NF-E4, GNA13, RUNX1, VDR, TEF ALOX15, CRB3, THBS1, FMR1, FLT3LG, VEGFA, KNG1 (includes EG:3827), Cell-To-Cell Signaling and Interaction 1.16E-03-3.28E-02 HSP90B1, JUN, TPM3, MPP5, RHOA, KISS1, AMBN, SAFB, GNA13, CXADR, GHRL, RBBP4 THBS1, XDH, CACNA1C, HDAC9 (includes EG:9734), DICER1, IGF2R, VEGFA, Cardiovascular System Development and 1.26E-03-2.44E-02 CEACAM1, ESAM, KNG1 (includes EG:3827), CCL4, JUN, CAMK2D, RHOA, Function LAMA1, EDNRA, FOXI1, NPFF, RUNX1, GHRL Drug Metabolism 1.26E-03-2.06E-02 VEGFA, SLC26A2, THBS1, XDH, CACNA1C, NCOA4, ABCC4, UNG Hair and Skin Development and Function 1.26E-03-2.06E-02 VEGFA, KNG1 (includes EG:3827), ELOVL3, MAPK13, VDR VEGFA, KNG1 (includes EG:3827), ENAH, ALOX15, THBS1, EPHA4, VDR, SIM1, Organ Development 1.26E-03-2.14E-02 DIO2 Post-Translational Modification 1.26E-03-3.28E-02 VEGFA, PRKDC, TGM1, BMI1, XDH, MYST4, MYLK2, SMG1 Protein Folding 1.26E-03-1.26E-03 VEGFA, TGM1 ENTPD4, XDH, ELOVL3, DICER1, DIO2, VEGFA, MTMR6, HSP90B1, JUN, KISS1, NCOA4, VDR, GHRL, UNG, ALOX15, SLC26A2, THBS1, CACNA1C, Small Molecule Biochemistry 1.26E-03-2.85E-02 SLC1A1, HSPD1, DIO3, KNG1 (includes EG:3827), PPAP2A, CCL4, TGM1, PLA2G2D, JMJD7-PLA2G4B, EDNRA, PDE5A, ABCC4 ALOX15, ENAH, THBS1, AKTIP, ZIC2, BECN1, CEACAM1, VEGFA, KNG1 Embryonic Development 1.67E-03-3.17E-02 (includes EG:3827), ROR2, HSP90B1, JUN, EZR, LAMA1, EDNRA, RUNX1, HIPK2, GHRL, RYK, CLIP1

ALOX15, ENAH, THBS1, ZIC2, AKTIP, EPHA4, FLT3LG, CEACAM1, VEGFA, Tissue Development 1.67E-03-3.17E-02 ROR2, HSP90B1, JUN, LAMA1, EDNRA, VDR, RUNX1, GHRL, RYK

Infection Mechanism 1.86E-03-2.06E-02 VEGFA, AKAP13, JUN, RHOA, ZC3HAV1, GNA13, CXADR SIAH1, BHMT, DLG2, HDAC9 (includes EG:9734), RUVBL1, MAPK13, BECN1, SLC2A3, POLE, VEGFA, CASP6, C9ORF86, HSP90B1, JUN, TUBA8, GPR4, HSP90AB1, GPR177, HOXA5, ZNF24 (includes EG:7572), CD274, VDR, HIPK2, Gastrointestinal Disease 1.97E-03-3.25E-02 UNG, HUWE1, GCH1, ALOX15, SLC26A2, BGN, HSPD1, DIO3, IGF2R, CEACAM1, RAD54B, AKAP13, KNG1 (includes EG:3827), LAMA4, PDE5A, MEP1A, KDM5A, RBBP4 RNA Post-Transcriptional Modification 2.48E-03-2.06E-02 RPP14, DICER1 GCGR, BGN, AKTIP, HDAC9 (includes EG:9734), WASF1, ELOVL3, DICER1, Organ Morphology 2.68E-03-3.09E-02 IGF2R, VEGFA, CAMK2D, LAMA1, KISS1, HBD, VDR FCAR, HDAC9 (includes EG:9734), EPHA4, MED28, DICER1, KSR1, VEGFA, ROR2, HSP90B1, JUN, BMI1, EZR, HOXA5, LAMA1, SAFB, VDR, GNA13, Cellular Development 3.01E-03-3.25E-02 ALOX15, PRKDC, THBS1, WASF1, DLX2, HSPD1, FLT3LG, IGF2R, AVIL, KNG1 (includes EG:3827), AKAP13, CCL4, KDM5D, EPB42, RHOA, IL10RA, EDNRA, CDC42SE2, RUNX1

TWF1, NPEPPS, DICER1, CSPP1, DYRK3, POLE, VEGFA, CAMK2D, GPR4, PTPRO, GRIN2C, EZR, CD274, SMG1, HIPK2, THBS1, MT1X, WASF1, SLC1A1, AKAP13, TGM1, RHOA, RUNX1, ABCC4, RBBP4, SIAH1, HDAC9 (includes Reproductive System Disease 3.03E-03-2.99E-02 EG:9734), EPHA4, ARL4D, KSR1, MTMR6, ROR2, CASP6, HSP90B1, C9ORF86, SERPINB9, JUN, TUBA8, HSP90AB1, HOXA5, ZNF24 (includes EG:7572), VDR, GBP2, GABRA3, ALOX15, PRKDC, PPP1R8, ETFA, HSPD1, FLT3LG, DNM1, CEACAM1, PPAP2A, EDNRA, PDE5A, EHBP1, CLEC10A

Amino Acid Metabolism 3.29E-03-2.06E-02 TGM1, EDNRA, SLC1A1, DIO2, DIO3

GCGR, ATP8A1 (includes EG:10396), ADCY4, C1QTNF5, XDH, MYLK2, DLG2, DENND1B, NPEPPS, MAPK13, BRCC3, TTC33, DIO2, VEGFA, OXR1, PTPRO, AMMECR1, CD274, SAFB, GNA13, HIPK2, UNG, ATP5G3, C6ORF204, CHGB, MAGT1, SLC26A2, MYST4, RHOBTB3, MT1X, ZIC2, RALB, CACNA1C, LARP4, NDST4, DIO3, GSTCD, WFDC5, AKAP13, TGM1, CCL4, DUOX2, EPB42, REEP3, MCEE, IL10RA, C18ORF45, RUNX1, C5ORF46, KDM5A, CLIP1, LDB3, ENAH, ENTPD4, LTBP2, RAB28, CLCNKB, PDDC1, EPHA4, RUVBL1, BECN1, KRTAP2- 4, KSR1, MTMR6, ALKBH8, FAM183A, CASP6, C9ORF86, JUN, RIF1, TUBA8, HSP90AB1, GARNL3, HOXA5, ABHD2, VDR, GPC6, GABRA3, RUNDC2A, ALOX15, PRKDC, IGF2R, FLT3LG, YLPM1, ARL3, CEACAM1, C8ORF42, RAD54B, ZNF714, YPEL2, CYP4V2, CDC42SE2, ADAMTSL1, SIM1, RUFY3, Genetic Disorder 3.83E-03-3.04E-02 SMEK1, EHBP1, RYK, NAV2 (includes EG:89797), TTC19, FMR1, MMP16, EML4, MT1M, C1ORF175, DICER1, POLE, SLFN12, HNRNPA3, CAMK2D, GPR4, UBXN4, GRIN2C, TNNT3, ARHGAP20, LAMA1, HBD, RASSF8, RIPK4, HUWE1, GCH1, THBS1, WASF1, SLC1A1, ALAD, LOC387761, PANK1, CCDC66, KNG1 (includes EG:3827), PSD3, RHOA, LIN28B, JMJD7-PLA2G4B, GMCL1, RPP14, SMCHD1, UHMK1, ABCC4, USP12, KCNK3, PIGL, HDAC9 (includes EG:9734), CC2D2A, CDKAL1, MAPK11, SLC2A3, CPEB3, ROR2, SUCLA2, HSP90B1, CCRL2, SFI1, RHOT1, PPP1R2, RRN3, GPR177, ZNF24 (includes EG:7572), GBP2, CA1 (includes EG:759), GHRL, NLRP3, ETFA, BGN, ATRX, GRHL1, ETNK1, HSPD1, HNRNPCL1, DNM1, NPFFR2, C12ORF51, PPAP2A, TPM3, LAMA4, TCP11L2, EDNRA, FOXI1, PDE5A, BRI3BP, MEP1A, C5ORF13, RTN3

Visual System Development and Function 4.06E-03-2.14E-02 VEGFA, KNG1 (includes EG:3827), ALOX15, THBS1 NAV2 (includes EG:89797), ATP8A1 (includes EG:10396), SFRS4, XDH, ADCY4, MYLK2, DLG2, C1ORF175, NPEPPS, DICER1, DIO2, VEGFA, CAMK2D, PTPRO, GRIN2C, ARHGAP20, RASSF8, C6ORF204, THBS1, CACNA1C, SLC1A1, WFDC5, AKAP13, KNG1 (includes EG:3827), LOC145814, CCL4, PSD3, CNOT7, RHOA, Cardiovascular Disease 4.07E-03-3.24E-02 LIN28B, SMCHD1, CLIP1, LTBP2, RAB28, KCNK3, PIGL, HDAC9 (includes EG:9734), CC2D2A, BECN1, MAPK11, CPEB3, KSR1, FAM183A, JUN, RIF1, TUBA8, GARNL3, VDR, ZFC3H1, CA1 (includes EG:759), GPC6, GABRA3, RUNDC2A, ALOX15, NLRP3, GRHL1, ETNK1, FLT3LG, IGF2R, DNM1, NPFFR2, LAMA4 EDNRA PDE5A MEP1A ADAMTSL1 SIM1 BGN, FMR1, TOB1, DICER1, KSR1, KNG1 (includes EG:3827), TGM1, BMI1, Connective Tissue Development and Function 4.07E-03-2.06E-02 JUN, TPM3, SAFB, AMBN, VDR, HIPK2, C5ORF13, GHRL SIAH1, PRKDC, ROR2, KDM5D, POU4F1, HOXA5, KISS1, NPEPPS, RAD23B, Organismal Development 4.07E-03-2.06E-02 RYK Skeletal and Muscular System Development ALOX15, LDB3, THBS1, FMR1, POU4F1, BGN, TOB1, MED28, VEGFA, ROR2, 4.07E-03-3.28E-02 and Function HSP90B1, BMI1, LAMA4, VDR, GHRL, RYK VEGFA, MTMR6, KNG1 (includes EG:3827), CCL4, TGM1, PPAP2A, PLA2G2D, Carbohydrate Metabolism 4.18E-03-2.85E-02 THBS1, JMJD7-PLA2G4B, KISS1 ALOX15, ELOVL3, MTMR6, VEGFA, KNG1 (includes EG:3827), PPAP2A, TGM1, Lipid Metabolism 4.18E-03-2.85E-02 CCL4, PLA2G2D, JMJD7-PLA2G4B, NCOA4, KISS1, VDR, GHRL FCAR, ENAH, PLCB2, XDH, GNRH2, TPM4, VEGFA, CCRL2, JUN, GPR4, PTPRO, EZR, KISS1, CD274, GNA13, VDR, GHRL, ACTR2, THBS1, BGN, Cellular Movement 4.55E-03-3.09E-02 WASF1, HSPD1, IGF2R, FLT3LG, DNM1, CEACAM1, KNG1 (includes EG:3827), CCL4, TPM3, RHOA ALOX15, NLRP3, LTBP2, XDH, FMR1, ZC3HAV1, CACNA1C, ARL4D, DIO2, Molecular Transport 6.03E-03-3.2E-02 PANK1, S1PR4, VEGFA, KNG1 (includes EG:3827), CCL4, CAMK2D, EDNRA, KISS1, UHMK1, GNA13, VDR, ABCC4, GHRL ALOX15, NLRP3, KCNK3, THBS1, XDH, CACNA1C, POLE, VEGFA, KNG1 Organismal Injury and Abnormalities 6.03E-03-2.14E-02 (includes EG:3827), TUBA8, GRIN2C, EDNRA, PDE5A, CD274, CA1 (includes EG:759), GHRL, GABRA3 RNA Trafficking 6.03E-03-2.06E-02 HNRNPA3, FMR1, ZC3HAV1 ALOX15, NLRP3, ATRX, HDAC9 (includes EG:9734), ALAD, MAPK13, MAPK11, Hematological Disease 6.12E-03-3.1E-02 POLE, VEGFA, HSP90B1, CCL4, JUN, TUBA8, HSP90AB1, EDNRA, PDE5A, CD274, HBD, VDR, RUNX1 FCAR, CEACAM1, VEGFA, PLCB2, CCL4, THBS1, RHOA, EPHA4, GNRH2, Immune Cell Trafficking 7.37E-03-3.09E-02 HSPD1, GNA13, FLT3LG Reproductive System Development and 7.57E-03-2.06E-02 CEACAM1, SIAH1, CCL4, TGM1, KDM5D, KISS1, NPEPPS, VDR Function SIAH1, PRKDC, ALOX15, FLT3LG, DNM1, CEACAM1, VEGFA, BMI1, JUN, Cell Cycle 7.65E-03-2.14E-02 PPAP2A, RHOA, CD274, RUNX1, HIPK2, CLIP1 PRKDC, ALOX15, PLCB2, XDH, MYLK2, CACNA1C, HSPD1, DICER1, DIO2, Cell Signaling 7.65E-03-2.85E-02 VEGFA, S1PR4, KNG1 (includes EG:3827), HSP90B1, JUN, CAMK2D, CCL4, KISS1, EDNRA, SMG1, VDR, GNA13, GHRL Immunological Disease 7.65E-03-2.98E-02 DNM1, VEGFA, CCL4, THBS1, RALB, CD274 XDH, FMR1, EPHA4, MAPK13, DICER1, BECN1, VEGFA, HSP90B1, BMI1, JUN, HOXA5, NHLH2, CD274, VDR, HBD, GNA13, HIPK2, GHRL, PRKDC, THBS1, Tissue Morphology 7.65E-03-2.31E-02 BGN, POU4F1, ATRX, TOB1, DLX2, HSPD1, FLT3LG, IGF2R, KNG1 (includes EG:3827), CCL4, RHOA, IL10RA, FOXI1, EDNRA, RUNX1, SIM1, RBBP4 ALOX15, GCH1, THBS1, SLC26A2, MMP16, RALB, HDAC9 (includes EG:9734), Skeletal and Muscular Disorders 8.79E-03-2.98E-02 CACNA1C, VEGFA, DNM1, ROR2, CAMK2D, BMI1, CCL4, CNOT7, RHOA, EDNRA, CD274, VDR FCAR, ALOX15, PLCB2, NLRP3, THBS1, RALB, HDAC9 (includes EG:9734), Cell-mediated Immune Response 9.72E-03-2.5E-02 EPHA4, GNRH2, HSPD1, UACA, VEGFA, CEACAM1, KNG1 (includes EG:3827), JUN, CCL4, PLA2G2D, RHOA, IL10RA, EDNRA, GNA13, GHRL THBS1, TOB1, DICER1, BECN1, FLT3LG, KSR1, VEGFA, KNG1 (includes Cellular Growth and Proliferation 1.07E-02-2.06E-02 EG:3827), BMI1, JUN, TPM3, CNOT7, RHOA, EDNRA, AMBN, RUNX1, HIPK2, C5ORF13, GHRL, RBBP4 FCAR, ALOX15, PRKDC, THBS1, HDAC9 (includes EG:9734), GNRH2, EPHA4, Hematological System Development and 1.09E-02-3.09E-02 DICER1, HSPD1, IGF2R, FLT3LG, VEGFA, HSP90B1, JUN, CCL4, BMI1, KDM5D, Function LAMA4, RHOA, HOXA5, GNA13, RUNX1, GHRL PRKDC, HDAC9 (includes EG:9734), EPHA4, DICER1, HSPD1, FLT3LG, IGF2R, Hematopoiesis 1.09E-02-2.06E-02 VEGFA, HSP90B1, CCL4, BMI1, KDM5D, RUNX1 ALOX15, BARHL1, SLC1A1, VEGFA, CASP6, KNG1 (includes EG:3827), JUN, Cellular Compromise 1.2E-02-2.85E-02 TGM1, EZR, RHOA, GNA13, UNG, RYK Psychological Disorders 1.26E-02-2.45E-02 GCH1, GCGR, GRIN2C, FMR1, WASF1, SLC1A1, NPEPPS, GHRL, GABRA3 DNM1, VEGFA, KNG1 (includes EG:3827), CCL4, JUN, THBS1, MMP16, RALB, Inflammatory Disease 1.28E-02-2.98E-02 CD274, VDR, HSPD1 Protein Trafficking 1.28E-02-3.2E-02 VEGFA, LTBP2, NLRP3, THBS1, RHOA, CACNA1C, UHMK1, ARL4D, GHRL HUWE1, PRKDC, MAGT1, SLC26A2, FMR1, ATRX, HDAC9 (includes EG:9734), Developmental Disorder 1.35E-02-3.17E-02 VEGFA, ROR2, JUN, HOXA5, EDNRA, VDR, HIPK2, RYK THBS1, SLC26A2, MMP16, XDH, RALB, VEGFA, DNM1, ROR2, CCL4, RHOA, Connective Tissue Disorders 1.39E-02-2.98E-02 CD274, AMBN, RUNX1, RYK XDH, CACNA1C, DIO2, VEGFA, S1PR4, PANK1, KNG1 (includes EG:3827), Vitamin and Mineral Metabolism 1.57E-02-2.22E-02 CAMK2D, CCL4, EDNRA, KISS1, VDR, GNA13, GHRL ENAH, FMR1, POU4F1, EPHA4, WASF1, VEGFA, DNM1, KNG1 (includes Nervous System Development and Function 1.58E-02-2.85E-02 EG:3827), LAMA4, RHOA, GNA13, RUNX1, SIM1, GABRA3, RYK Dermatological Diseases and Conditions 1.71E-02-2.14E-02 VEGFA, CCL4, THBS1, PDE5A, EDNRA FCAR, ALOX15, NLRP3, THBS1, RALB, HDAC9 (includes EG:9734), GNRH2, Antigen Presentation 1.84E-02-2.5E-02 HSPD1, FLT3LG, UACA, VEGFA, KNG1 (includes EG:3827), CCL4, PLA2G2D, RHOA, EDNRA, GNA13, GHRL FCAR, ALOX15, NLRP3, THBS1, RALB, HDAC9 (includes EG:9734), GNRH2, Humoral Immune Response 1.84E-02-2.5E-02 HSPD1, UACA, VEGFA, KNG1 (includes EG:3827), CCL4, PLA2G2D, RHOA, EDNRA, GNA13, GHRL FCAR, ALOX15, NLRP3, THBS1, RALB, HDAC9 (includes EG:9734), GNRH2, Inflammatory Response 1.84E-02-2.78E-02 HSPD1, FLT3LG, UACA, VEGFA, KNG1 (includes EG:3827), CCL4, PLA2G2D, RHOA, EDNRA, GNA13, GHRL Respiratory System Development and Function 1.95E-02-2.06E-02 COX11, EDNRA, MAN1A2, DICER1 Auditory Disease 2.06E-02-2.06E-02 BARHL1 Auditory and Vestibular System Development 2.06E-02-2.44E-02 VEGFA, BARHL1, DIO2 and Function GCH1, GCGR, GRIN2C, FMR1, CACNA1C, ENOX2, SLC1A1, EPHA4, HIPK2, Behavior 2.06E-02-2.44E-02 UNG, GHRL, GABRA3 DNA Replication, Recombination, and Repair 2.06E-02-2.6E-02 SIAH1, PRKDC, ENTPD4, PDE5A, SMG1, DICER1, RUNX1, BECN1 Endocrine System Disorders 2.06E-02-2.06E-02 GCGR, VDR, DIO3 Hepatic System Disease 2.06E-02-2.06E-02 JUN, RHOA, XDH, DIO3 TRIM7, TWF1, LTBP2, RAB28, CDKAL1, MED28, CSPP1, SFXN3, SLC2A3, POLE, ALKBH8, FAM183A, CCRL2, TUBA8, GRIN2C, VDR, CA1 (includes EG:759), GABRA3, HUWE1, GRTP1, BGN, MT1X, RALB, CACNA1C, RAB8A, Infectious Disease 2.06E-02-3.12E-02 REG3A (includes EG:5068), FLT3LG, SLU7, IGF2R, DNM1, PANK1, AKAP13, CCL4, KDM5D, RHOA, GYG1, IL10RA, PDE5A, EDNRA, RTN3, CLEC10A, ZNF552 Lymphoid Tissue Structure and Development 2.06E-02-2.06E-02 VEGFA, ROR2 Metabolic Disease 2.06E-02-2.06E-02 XDH, SLC1A1, ALAD, DIO3 Nucleic Acid Metabolism 2.06E-02-2.06E-02 ENTPD4, XDH, PDE5A, ABCC4, UNG Nutritional Disease 2.06E-02-2.06E-02 GHRL Ophthalmic Disease 2.06E-02-2.14E-02 VEGFA, THBS1, HSPD1 Organismal Functions 2.06E-02-2.06E-02 VEGFA FCAR, THBS1, CLCNKB, VEGFA, DNM1, KNG1 (includes EG:3827), JUN, CCL4, Renal and Urological Disease 2.06E-02-2.24E-02 GRIN2C, AMMECR1, PDE5A, EDNRA, MEP1A, VDR, CA1 (includes EG:759) Renal and Urological System Development and 2.06E-02-2.06E-02 THBS1, BGN, FOXI1 Function KCNK3, HDAC9 (includes EG:9734), DICER1, POLE, VEGFA, KNG1 (includes Respiratory Disease 2.06E-02-2.39E-02 EG:3827), HSP90B1, JUN, HSP90AB1, TUBA8, PDE5A, VDR, HIPK2, SMEK1, CLIP1 Tumor Morphology 2.06E-02-2.85E-02 VEGFA, HSP90B1, KISS1, CD274 Table S7: Significant differentially expressed genes (P -Value<0.05, Fold Change≥1.4), 2 vs. 0.4 Gy irradiation Genbank Fold Change P -Value Gene Symbol Description Accession 7.4496837 0.020474989 BE173582 BE173582 BE173582 RC2-HT0560-290200-014-f06 HT0560 Homo sapiens cDNA, mRNA sequence [BE173582] 6.5806212 0.025803981 BE004814 BE004814 BE004814 MR2-BN0114-020500-006-e07 BN0114 Homo sapiens cDNA, mRNA sequence [BE004814] 6.5418015 0.02384404 A_32_P225328 AA418814 zw01a02.s1 Soares_NhHMPu_S1 Homo sapiens cDNA clone IMAGE:767978 3', mRNA 6.057398 0.046198867 AA418814 AA418814 sequence [AA418814] AA235034 zs36d01.s1 Soares_NhHMPu_S1 Homo sapiens cDNA clone IMAGE:687265 3', mRNA sequence 5.458468 0.048552595 AA235034 AA235034 [AA235034] 5.1782384 0.027508697 CN391963 CN391963 CN391963 17000599942841 GRN_PRENEU Homo sapiens cDNA 5', mRNA sequence [CN391963] 5.0159893 0.022022381 A_32_P80295 AA635126 ae57g03.s1 Stratagene lung carcinoma 937218 Homo sapiens cDNA clone IMAGE:951028 3' 4.7891273 0.015699474 AA635126 AA635126 similar to contains Alu repetitive element;, mRNA sequence [AA635126] BU684362 UI-CF-EN0-aco-n-23-0-UI.s1 UI-CF-EN0 Homo sapiens cDNA clone UI-CF-EN0-aco-n-23-0-UI 4.5180273 0.03205222 BU684362 BU684362 3', mRNA sequence [BU684362] c50-1 cDNA subtractive library of human rectum adencarcinoma Homo sapiens cDNA, mRNA sequence 4.451793 0.038232867 CK570365 CK570365 [CK570365] BX115105 Soares_pregnant_uterus_NbHPU Homo sapiens cDNA clone IMAGp998H081169, mRNA 4.3932953 0.00749338 BX115105 BX115105 sequence [BX115105] 4.381348 0.028857462 A_32_P82293 4.213484 0.035392895 AK123610 AK123610 Homo sapiens cDNA FLJ41616 fis, clone CTONG3003553. [AK123610] 4.2063847 0.02217205 NM_014143 CD274 Homo sapiens CD274 molecule (CD274), mRNA [NM_014143] BE855644 7g11e06.x1 NCI_CGAP_Brn23 Homo sapiens cDNA clone IMAGE:3306178 3', mRNA sequence 4.2033954 0.01914482 BE855644 BE855644 [BE855644] 4.148076 0.019338109 A_24_P315885 4.137283 0.003457273 THC2608799 4.129927 0.001859862 NM_052866 ADAMTSL1 Homo sapiens ADAMTS-like 1 (ADAMTSL1), transcript variant 2, mRNA [NM_052866] AA779434 af22b10.s1 Soares_total_fetus_Nb2HF8_9w Homo sapiens cDNA clone IMAGE:1032379 3', 4.1007633 0.044734858 AA779434 AA779434 mRNA sequence [AA779434] AA593970 nn01c05.s1 NCI_CGAP_Co9 Homo sapiens cDNA clone IMAGE:1076456 3', mRNA sequence 4.0833087 0.001699564 AA593970 AA593970 [AA593970] 4.0131307 0.01564024 BE708118 BE708118 BE708118 MR0-HT0559-230500-021-a08_1 HT0559 Homo sapiens cDNA, mRNA sequence [BE708118] 3.9509885 0.009507914 A_32_P2303 BX115105 Soares_pregnant_uterus_NbHPU Homo sapiens cDNA clone IMAGp998H081169, mRNA 3.9283826 0.010912928 BX115105 BX115105 sequence [BX115105] 3.9136176 0.048054427 NM_014625 NPHS2 Homo sapiens nephrosis 2, idiopathic, steroid-resistant (podocin) (NPHS2), mRNA [NM_014625] 3.8513677 0.002687195 NR_003125 LOC85391 Homo sapiens RNA, small nucleolar (LOC85391) on chromosome 11 [NR_003125] 3.8472888 0.03404857 BE156557 BE156557 BE156557 QV0-HT0368-090200-099-d10 HT0368 Homo sapiens cDNA, mRNA sequence [BE156557] 3.7366867 0.03576432 ENST00000260303 3.6990626 0.023347802 XR_015273 LOC728371 PREDICTED: Homo sapiens similar to ankyrin repeat domain 20A (LOC728371), mRNA [XR_015273] ALU1_HUMAN (P39188) Alu subfamily J sequence contamination warning entry, partial (6%) 3.6936631 0.038091928 THC2520867 [THC2520867] 3.6620421 0.040679704 THC2677796 3.6524696 0.017321412 BE175081 BE175081 BE175081 QV2-HT0577-250400-166-d10 HT0577 Homo sapiens cDNA, mRNA sequence [BE175081] 3.6479635 0.036172137 BE826587 BE826587 BE826587 QV1-EN0042-300500-224-e04 EN0042 Homo sapiens cDNA, mRNA sequence [BE826587] CA414006 UI-H-EZ0-ban-f-19-0-UI.s1 NCI_CGAP_Ch1 Homo sapiens cDNA clone UI-H-EZ0-ban-f-19-0- 3.640309 0.022215607 CA414006 CA414006 UI 3', mRNA sequence [CA414006] Homo sapiens keratin associated protein 2-4, mRNA (cDNA clone MGC:74790 IMAGE:3907481), complete 3.589494 0.003647879 BC063625 KRTAP2-4 cds. [BC063625] 3.498008 0.030538011 A_32_P88605 Homo sapiens protein tyrosine phosphatase, receptor type, O (PTPRO), transcript variant 1, mRNA 3.497605 0.00775243 NM_030667 PTPRO [NM 030667] 3.4954975 0.001780532 AW994037 AW994037 AW994037 RC3-BN0036-090200-011-f03 BN0036 Homo sapiens cDNA, mRNA sequence [AW994037] Homo sapiens hypothetical gene supported by BC013438, mRNA (cDNA clone IMAGE:3899073), partial 3.4837506 0.03450945 LOC375295 cds. [BC013438] BX281073 BX281073 NCI_CGAP_Lu24 Homo sapiens cDNA clone IMAGp998O175628 ; 3.4750195 0.020507107 BX281073 BX281073 IMAGE:2273128, mRNA sequence [BX281073] 3.4515235 0.03740514 NP389850 GB|AF399571.1|AAK95056.1 olfactory receptor [Homo sapiens] [NP389850] 3.4338923 0.015730431 NM_206827 RASL11A Homo sapiens RAS-like, family 11, member A (RASL11A), mRNA [NM_206827] 602039925F2 NCI_CGAP_Brn67 Homo sapiens cDNA clone IMAGE:4177446 5', mRNA sequence 3.4152215 0.04348502 BF527031 BF527031 [BF527031] 3.3960404 8.16E-04 NM_182499 TDRD10 Homo sapiens tudor domain containing 10 (TDRD10), mRNA [NM_182499] 3.3791614 0.043366298 NM_021013 KRT34 Homo sapiens keratin 34 (KRT34), mRNA [NM_021013] 3.3501503 1.86E-04 NM_016585 THEG Homo sapiens Theg homolog (mouse) (THEG), transcript variant 1, mRNA [NM_016585] 3.3448963 0.022188967 A_32_P148636

3.3402188 0.023365254 NM_004895 NLRP3 Homo sapiens NLR family, pyrin domain containing 3 (NLRP3), transcript variant 1, mRNA [NM_004895] 3.319344 0.008686633 AF293366 PCMTD1 Homo sapiens clone 122482 unknown mRNA. [AF293366] 3.287633 0.047398187 AL832535 LOC157627 Homo sapiens mRNA; cDNA DKFZp547J1816 (from clone DKFZp547J1816). [AL832535] 3.2742872 0.012837925 NM_000576 IL1B Homo sapiens interleukin 1, beta (IL1B), mRNA [NM_000576] 3.2622862 0.008224156 A_32_P167212 3.256188 0.03072841 A_32_P71212 Q91873_XENLA (Q91873) laevis tandemly arranged embryonic U1 snRNA genes U1a/U1b, partial 3.233746 0.021714212 THC2729730 (13%) [THC2729730] AL536879 Homo sapiens FETAL BRAIN Homo sapiens cDNA clone CS0DF020YM21 3-PRIME, mRNA 3.1952715 0.010303524 AL536879 AL536879 sequence [AL536879] 3.1845207 0.030380901 AV645774 AV645774 AV645774 AV645774 GLC Homo sapiens cDNA clone GLCAEF02 3', mRNA sequence [AV645774] AI685431 tt88b11.x1 NCI_CGAP_Pr28 Homo sapiens cDNA clone IMAGE:2248605 3', mRNA sequence 3.1789818 0.036870528 AI685431 AI685431 [AI685431] AA890297 aj94e10.s1 Soares_parathyroid_tumor_NbHPA Homo sapiens cDNA clone IMAGE:1404138 3', 3.1689632 0.027360782 THC2780391 mRNA sequence [AA890297] W60781 zd26f05.r1 Soares_fetal_heart_NbHH19W Homo sapiens cDNA clone IMAGE:341793 5' similar to 3.161054 0.021140933 W60781 W60781 gb:J02874 FATTY ACID-BINDING PROTEIN, ADIPOCYTE (HUMAN);, mRNA sequence [W60781] AA303143 EST13031 tumor I Homo sapiens cDNA 5' end similar to hypothetical protein KIAA0222, 3.1571689 0.041052565 AA303143 AA303143 mRNA sequence [AA303143] 3.1419957 0.00487781 NM_014375 FETUB Homo sapiens fetuin B (FETUB), mRNA [NM_014375] 3.1043627 0.041379288 AV722457 AV722457 AV722457 HTB Homo sapiens cDNA clone HTBAMH03 5', mRNA sequence [AV722457] 3.0953522 0.027020726 THC2676635 CA307538 UI-H-FT1-bic-o-24-0-UI.s1 NCI_CGAP_FT1 Homo sapiens cDNA clone UI-H-FT1-bic-o-24-0- 3.0754728 0.010021865 THC2560137 UI 3', mRNA sequence [CA307538] BX457728 BX457728 Homo sapiens NEUROBLASTOMA Homo sapiens cDNA clone CS0DA003YD09 3- 3.0595484 0.008932386 BX457728 BX457728 PRIME, mRNA sequence [BX457728] 3.055075 0.04649837 NM_004566 PFKFB3 Homo sapiens 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3), mRNA [NM_004566] 3.0449693 0.038048442 A_32_P1841 AL356953 leucine-rich repeat-containing G protein-coupled receptor 6 {Homo sapiens} (exp=0; wgp=1; 3.0370107 0.026084732 THC2705989 cg=0), partial (4%) [THC2752981] AA554768 ni37h02.s1 NCI_CGAP_Lu1 Homo sapiens cDNA clone IMAGE:979059 3' similar to gb:D29805 3.0068088 0.02130563 AA554768 AA554768 N-ACETYLLACTOSAMINE SYNTHASE (HUMAN);, mRNA sequence [AA554768] AW079854 xe54e05.x1 NCI_CGAP_Ut3 Homo sapiens cDNA clone IMAGE:2611712 3', mRNA sequence 3.003226 0.045061182 AW079854 AW079854 [AW079854] Homo sapiens transmembrane protein 49, mRNA (cDNA clone IMAGE:4295896), with apparent retained 2.9961622 0.026871251 BC024020 TMEM49 intron. [BC024020] 2.9791129 0.006583171 NM_019016 KRT24 Homo sapiens keratin 24 (KRT24), mRNA [NM_019016] 2.967462 0.028728558 THC2722117 2.9669144 0.005472489 NM_015174 KIAA1086 Homo sapiens KIAA1086 (KIAA1086), mRNA [NM_015174] 2.926427 0.039247774 THC2741789 2.9039984 0.044169884 NM_145664 SPANXB2 Homo sapiens SPANX family, member B2 (SPANXB2), mRNA [NM_145664] 2.8952596 5.80E-04 NM_032153 ZIC4 Homo sapiens Zic family member 4 (ZIC4), mRNA [NM_032153] PREDICTED: Homo sapiens similar to gamma-aminobutyric acid (GABA-A) receptor, subunit epsilon 2.881841 0.003246293 ENST00000284414 (LOC651250), mRNA [XR 019083] 2.873949 0.007674599 AF090937 SORBS2 Homo sapiens clone HQ0618 PRO0618 mRNA, complete cds. [AF090937] 2.8525686 0.00835639 ENST00000303979 2.8400116 0.00979091 THC2525408 AV738929 AV738929 CB Homo sapiens cDNA clone CBCCMG04 5', mRNA sequence [AV738929] 2.8363094 0.0310893 NM_012288 TRAM2 Homo sapiens translocation associated membrane protein 2 (TRAM2), mRNA [NM_012288] 2.8177683 0.0368026 BE696323 BE696323 BE696323 RC3-CT0347-010700-019-c08 CT0347 Homo sapiens cDNA, mRNA sequence [BE696323] 2.8174345 0.017476656 THC2777514 2.8146923 0.0333595 NM_002113 CFHR1 Homo sapiens complement factor H-related 1 (CFHR1), mRNA [NM_002113] 2.7656307 0.00720425 THC2596018 Q99834_HUMAN (Q99834) Nuclear antigen H731, partial (21%) [THC2580379] 2.755521 8.64E-04 A_32_P169243 AGENCOURT_10278709 NIH_MGC_82 Homo sapiens cDNA clone IMAGE:6592525 5', mRNA sequence 2.7382298 0.02297033 BU561469 BU561469 [BU561469] UI-H-FT2-bjg-p-24-0-UI.s1 NCI_CGAP_FT2 Homo sapiens cDNA clone UI-H-FT2-bjg-p-24-0-UI 3', mRNA 2.7368755 0.02417048 CB529149 CB529149 sequence [CB529149] 2.7288632 0.04434953 AF132203 AF132203 Homo sapiens PRO1933 mRNA, complete cds. [AF132203] 2.7288105 0.040122364 AK000177 C6orf61 Homo sapiens cDNA FLJ20170 fis, clone COL09549. [AK000177] 2.7208083 0.035274297 NM_182499 TDRD10 Homo sapiens tudor domain containing 10 (TDRD10), mRNA [NM_182499] 2.702401 0.0179376 AK095453 AK095453 Homo sapiens cDNA FLJ38134 fis, clone D9OST2000440. [AK095453] 2.700912 0.002194932 AK024926 AK024926 Homo sapiens cDNA: FLJ21273 fis, clone COL01778. [AK024926] Plasminogen activator inhibitor 2 precursor (PAI-2) (Placental plasminogen activator inhibitor) (Monocyte 2.674689 0.005578949 SERPINB2 Arg-serpin) (Urokinase inhibitor). [Source:Uniprot/SWISSPROT;Acc:P05120] [ENST00000299502] 2.6641781 0.03625895 ENST00000308894 Homo sapiens HSPC324 mRNA, partial cds. [AF161442] AI824599 wc18g09.x1 NCI_CGAP_Pr28 Homo sapiens cDNA clone IMAGE:2315584 3', mRNA sequence 2.6472297 0.01511364 AI824599 AI824599 [AI824599] 2.638365 3.39E-04 NM_005076 CNTN2 Homo sapiens contactin 2 (axonal) (CNTN2), mRNA [NM_005076] 2.6248202 0.003837628 BC089451 BC089451 Homo sapiens cDNA clone IMAGE:30554612. [BC089451] 2.6142004 0.0486151 AW797858 AW797858 AW797858 CM0-UM0042-130300-280-d11 UM0042 Homo sapiens cDNA, mRNA sequence [AW797858]

2.6131477 0.011920925 CA948108 CA948108 CA948108 iq21e07.x1 HR85 islet Homo sapiens cDNA clone IMAGE: 3', mRNA sequence [CA948108] 2.6109018 0.017022096 NM_000634 IL8RA Homo sapiens interleukin 8 receptor, alpha (IL8RA), mRNA [NM_000634] Homo sapiens serpin peptidase inhibitor, clade B (ovalbumin), member 7 (SERPINB7), transcript variant 1, 2.586396 0.008620141 NM_003784 SERPINB7 mRNA [NM 003784] 2.5788794 0.032230973 NM_001025105 CSNK1A1 Homo sapiens , alpha 1 (CSNK1A1), transcript variant 1, mRNA [NM_001025105] 2.5440967 0.007238165 NM_006408 AGR2 Homo sapiens anterior gradient homolog 2 (Xenopus laevis) (AGR2), mRNA [NM_006408] 2.5258923 0.013776466 NM_007036 ESM1 Homo sapiens endothelial cell-specific molecule 1 (ESM1), mRNA [NM_007036] 2.5202603 0.045266 NM_000301 PLG Homo sapiens plasminogen (PLG), mRNA [NM_000301] BM997687 UI-H-DH0-aus-i-05-0-UI.s1 NCI_CGAP_DH0 Homo sapiens cDNA clone IMAGE:5873740 3', 2.5145874 0.027255718 BM997687 BM997687 mRNA sequence [BM997687] UI-H-FH1-bfk-l-14-0-UI.s1 NCI_CGAP_FH1 Homo sapiens cDNA clone UI-H-FH1-bfk-l-14-0-UI 3', mRNA 2.4923427 0.04889105 BU618765 BU618765 sequence [BU618765] 2.4817986 0.02642588 NM_181077 GOLGA8A Homo sapiens golgi autoantigen, golgin subfamily a, 8A (GOLGA8A), mRNA [NM_181077] 2.4804358 0.023954868 BC036557 KIAA1394 Homo sapiens KIAA1394 protein, mRNA (cDNA clone IMAGE:4310128), complete cds. [BC036557] 2.466451 0.004713438 NM_173678 FLJ40722 Homo sapiens hypothetical protein FLJ40722 (FLJ40722), mRNA [NM_173678] 2.4635196 0.031716067 NM_173481 C19orf21 Homo sapiens chromosome 19 open reading frame 21 (C19orf21), mRNA [NM_173481] Homo sapiens C-type lectin domain family 10, member A (CLEC10A), transcript variant 1, mRNA 2.459063 0.006335009 NM_182906 CLEC10A [NM 182906] UI-H-DF0-bey-h-15-0-UI.s1 NCI_CGAP_DF0 Homo sapiens cDNA clone UI-H-DF0-bey-h-15-0-UI 3', 2.4510896 0.021962937 BU616488 BU616488 mRNA sequence [BU616488] 2.4491282 0.034600727 A_32_P101799 2.446481 0.027394753 NM_015037 KIAA0913 Homo sapiens KIAA0913 (KIAA0913), mRNA [NM_015037] 2.4376948 0.005452444 NM_147175 HS6ST2 Homo sapiens heparan sulfate 6-O-sulfotransferase 2 (HS6ST2), transcript variant S, mRNA [NM_147175] 2.436609 0.008754731 NM_006622 PLK2 Homo sapiens polo-like kinase 2 (Drosophila) (PLK2), mRNA [NM_006622] 2.4362588 0.014321825 NM_153269 C20orf96 Homo sapiens chromosome 20 open reading frame 96 (C20orf96), mRNA [NM_153269] 2.430557 0.036181767 AK123912 AK123912 Homo sapiens cDNA FLJ41918 fis, clone PERIC2002243. [AK123912] 2.4222627 0.024664922 AK096498 AK096498 Homo sapiens cDNA FLJ39179 fis, clone OCBBF2004147. [AK096498] 2.4133842 0.019671649 NM_007078 LDB3 Homo sapiens LIM domain binding 3 (LDB3), transcript variant 1, mRNA [NM_007078] 2.4069386 0.006702367 NM_152406 AFAP1L1 Homo sapiens actin filament associated protein 1-like 1 (AFAP1L1), mRNA [NM_152406] 2.3877656 0.049371455 NM_020809 ARHGAP20 Homo sapiens Rho GTPase activating protein 20 (ARHGAP20), mRNA [NM_020809] 2.3875718 0.04608914 NM_006399 BATF Homo sapiens basic leucine zipper transcription factor, ATF-like (BATF), mRNA [NM_006399] 2.3846061 0.04398145 A_24_P238819 2.3772707 0.03527131 NM_017982 SUSD4 Homo sapiens sushi domain containing 4 (SUSD4), transcript variant 1, mRNA [NM_017982] AI700316 wd06c02.x1 NCI_CGAP_Co3 Homo sapiens cDNA clone IMAGE:2327330 3' similar to 2.375378 0.022364264 AI700316 AI700316 gb:Z22533 SERINE/THREONINE-PROTEIN KINASE RECEPTOR R3 PRECURSOR (HUMAN);, mRNA sequence [AI700316] 2.3737056 0.028881349 NM_213602 CD33L3 Homo sapiens CD33 molecule-like 3 (CD33L3), mRNA [NM_213602] 2.372354 0.023067787 BE825944 BE825944 BE825944 CM2-EN0014-310500-207-g07 EN0014 Homo sapiens cDNA, mRNA sequence [BE825944] 2.370576 0.030348428 NM_020851 ISLR2 Homo sapiens immunoglobulin superfamily containing leucine-rich repeat 2 (ISLR2), mRNA [NM_020851]

2.3700497 0.00749752 NM_016541 GNG13 Homo sapiens guanine nucleotide binding protein (G protein), gamma 13 (GNG13), mRNA [NM_016541] 2.369916 0.039573573 NM_002514 NOV Homo sapiens nephroblastoma overexpressed gene (NOV), mRNA [NM_002514] 2.3693926 0.006784895 AF147723 AF147723 Homo sapiens lipopolysaccharide specific response-68 protein (LSR68) mRNA, complete cds. [AF147723] 2.3644395 0.005671479 NM_173342 KCNIP2 Homo sapiens Kv channel interacting protein 2 (KCNIP2), transcript variant 8, mRNA [NM_173342] 2.3554707 0.042065043 NM_012306 FAIM2 Homo sapiens Fas apoptotic inhibitory molecule 2 (FAIM2), mRNA [NM_012306] 2.3546515 0.034689277 THC2560357 Homo sapiens cDNA FLJ16078 fis, clone NT2NE2003252, weakly similar to Human putative 2.3496537 0.009889022 ENST00000334770 serine/threonine protein kinase PRK (prk) mRNA. [AK122648] 2.3457375 0.0066557 AK126431 LOC654433 Homo sapiens cDNA FLJ44467 fis, clone UTERU2025891. [AK126431] 2.3394036 0.001542045 NM_006953 UPK3A Homo sapiens uroplakin 3A (UPK3A), mRNA [NM_006953] 2.336202 0.013202902 NM_198455 SSPO Homo sapiens SCO-spondin homolog (Bos taurus) (SSPO), mRNA [NM_198455] Homo sapiens hypothetical protein MGC16075, mRNA (cDNA clone MGC:16075 IMAGE:3616854), 2.3314862 0.009471986 BC007354 MGC16075 complete cds. [BC007354] 2.3301737 0.00162148 A_24_P7494 2.3270197 0.03558816 NM_006615 CAPN9 Homo sapiens 9 (CAPN9), transcript variant 1, mRNA [NM_006615] 2.3227556 9.34E-04 NM_006237 POU4F1 Homo sapiens POU domain, class 4, transcription factor 1 (POU4F1), mRNA [NM_006237] 2.3168347 0.046289146 NM_173590 C11orf36 Homo sapiens chromosome 11 open reading frame 36 (C11orf36), mRNA [NM_173590] BX332393 Homo sapiens NEUROBLASTOMA COT 25-NORMALIZED Homo sapiens cDNA clone 2.3129995 0.016741745 BX332393 BX332393 CS0DC011YJ08 3-PRIME, mRNA sequence [BX332393] 2.3098154 0.008473084 U09850 ZNF143 Human zinc finger protein (ZNF143) mRNA, complete cds. [U09850] 2.3012397 0.045200657 THC2666227 Homo sapiens cyclin-dependent kinase inhibitor 1A (p21, Cip1) (CDKN1A), transcript variant 2, mRNA 2.2961142 0.046182565 NM_078467 CDKN1A [NM 078467] 2.2929773 0.022820598 NM_003810 TNFSF10 Homo sapiens tumor necrosis factor (ligand) superfamily, member 10 (TNFSF10), mRNA [NM_003810] 2.2916362 0.030273562 NM_016279 CDH9 Homo sapiens cadherin 9, type 2 (T1-cadherin) (CDH9), mRNA [NM_016279] 2.2914748 0.016004868 NM_152394 C3orf44 Homo sapiens chromosome 3 open reading frame 44 (C3orf44), mRNA [NM_152394] 2.2782407 0.002584587 NM_004073 PLK3 Homo sapiens polo-like kinase 3 (Drosophila) (PLK3), mRNA [NM_004073] 2.2778654 0.004499627 NM_178569 C5orf38 Homo sapiens chromosome 5 open reading frame 38 (C5orf38), mRNA [NM_178569] 2.2739484 0.004241937 NM_003125 SPRR1B Homo sapiens small proline-rich protein 1B (cornifin) (SPRR1B), mRNA [NM_003125] 2.269458 0.007050513 AK131396 AK131396 Homo sapiens cDNA FLJ16488 fis, clone BRTHA3008826. [AK131396] 2.265858 0.027459724 NM_000483 APOC2 Homo sapiens apolipoprotein C-II (APOC2), mRNA [NM_000483] 2.2608473 0.044483013 NM_025217 ULBP2 Homo sapiens UL16 binding protein 2 (ULBP2), mRNA [NM_025217] 2.2556918 0.02603006 NM_017523 XAF1 Homo sapiens XIAP associated factor-1 (XAF1), transcript variant 1, mRNA [NM_017523] 2.2541027 0.02705453 NM_022124 CDH23 Homo sapiens cadherin-like 23 (CDH23), transcript variant 1, mRNA [NM_022124] 2.2509549 0.027930915 NM_000835 GRIN2C Homo sapiens glutamate receptor, ionotropic, N-methyl D-aspartate 2C (GRIN2C), mRNA [NM_000835] 2.237894 0.03774925 NM_016148 SHANK1 Homo sapiens SH3 and multiple ankyrin repeat domains 1 (SHANK1), mRNA [NM_016148] ALU2_HUMAN (P39189) Alu subfamily SB sequence contamination warning entry, partial (4%) 2.2286932 0.013898107 THC2654039 [THC2654039] 2.1825695 0.034196205 NM_006398 UBD Homo sapiens ubiquitin D (UBD), mRNA [NM_006398] 2.1672654 0.009683834 THC2719525 2.1629028 0.047768336 THC2659814 Q495E5_HUMAN (Q495E5) Nanos homolog 3 (Drosophila), partial (10%) [THC2659814] 2.1510477 0.01849407 NM_000852 GSTP1 Homo sapiens glutathione S-transferase pi (GSTP1), mRNA [NM_000852] 2.1443133 0.021162929 THC2611277 NM_069973 F08G5.6 {Caenorhabditis elegans} (exp=-1; wgp=0; cg=0), partial (5%) [THC2611277] 2.1413558 0.04075418 AK091132 AK091132 Homo sapiens cDNA FLJ33813 fis, clone CTONG2002744. [AK091132] 2.13908 0.017348083 A_23_P247 2.1379573 0.016973192 NM_153370 PI16 Homo sapiens peptidase inhibitor 16 (PI16), mRNA [NM_153370] 2.136857 0.004152278 NM_021215 C20orf77 Homo sapiens chromosome 20 open reading frame 77 (C20orf77), mRNA [NM_021215] 2.1315207 0.042103495 NM_001711 BGN Homo sapiens biglycan (BGN), mRNA [NM_001711] 2.126914 0.04919589 NM_013397 C6orf49 Homo sapiens chromosome 6 open reading frame 49 (C6orf49), mRNA [NM_013397] 2.1158485 0.01646846 THC2681034 AF179597 connexin 59 {Homo sapiens} (exp=-1; wgp=0; cg=0), partial (10%) [THC2681034] 2.1094804 0.030322766 AW946823 AW946823 AW946823 RC2-ET0022-080500-012-b10 ET0022 Homo sapiens cDNA, mRNA sequence [AW946823]

2.1082962 0.032859474 NM_025216 WNT10A Homo sapiens wingless-type MMTV integration site family, member 10A (WNT10A), mRNA [NM_025216] Homo sapiens ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme) 2.1068876 0.024173003 NM_003183 ADAM17 (ADAM17), mRNA [NM 003183] Homo sapiens epithelial membrane protein 1, mRNA (cDNA clone IMAGE:4691099), partial cds. 2.097581 0.027628856 BC017854 EMP1 [BC017854] 2.096721 0.017628895 NM_173858 VN1R5 Homo sapiens vomeronasal 1 receptor 5 (VN1R5), mRNA [NM_173858] 2.096653 0.04828632 A_23_P84974 2.0938704 0.014807558 NM_002021 FMO1 Homo sapiens flavin containing 1 (FMO1), mRNA [NM_002021] 2.0913992 0.02477781 A_24_P332911 2.0869813 0.00682708 A_32_P209924 2.080496 0.040653717 NM_001039618 CREBZF Homo sapiens CREB/ATF bZIP transcription factor (CREBZF), mRNA [NM_001039618] 2.0801785 0.046255704 NM_182539 RP11-444E17.2 Homo sapiens hypothetical protein MGC33600 (MGC33600), mRNA [NM_182539] BU678941 UI-CF-DU1-aat-a-09-0-UI.s1 UI-CF-DU1 Homo sapiens cDNA clone UI-CF-DU1-aat-a-09-0-UI 2.0781488 0.048041858 THC2680668 3', mRNA sequence [BU678941] 2.0533836 0.024095135 A_32_P35031 Homo sapiens CREB binding protein (Rubinstein-Taybi syndrome) (CREBBP), transcript variant 1, mRNA 2.0508573 0.030734206 NM_004380 CREBBP [NM 004380] 2.0460584 0.027952433 NM_001939 DRP2 Homo sapiens dystrophin related protein 2 (DRP2), mRNA [NM_001939] Homo sapiens solute carrier family 6 (neurotransmitter transporter, GABA), member 13, mRNA (cDNA clone 2.0453887 0.036989115 BC020867 SLC6A13 IMAGE:4594185), complete cds. [BC020867] 2.044178 0.002792339 NM_024843 CYBRD1 Homo sapiens cytochrome b reductase 1 (CYBRD1), mRNA [NM_024843] 2.0437527 0.002662787 A_32_P42666

2.041994 0.014383965 BQ334425 BQ334425 BQ334425 RC2-MT0142-151100-017-a11 MT0142 Homo sapiens cDNA, mRNA sequence [BQ334425] 2.0352573 0.049840778 NM_001946 DUSP6 Homo sapiens dual specificity phosphatase 6 (DUSP6), transcript variant 1, mRNA [NM_001946] 2.034643 0.014710669 U77706 U77706 Human laminin alpha 4 chain (LAMA4*-1) mRNA, complete cds. [U77706] 2.0337768 0.022050392 NM_002531 NTSR1 Homo sapiens 1 (high affinity) (NTSR1), mRNA [NM_002531] 2.0315459 0.034858163 NM_005840 SPRY3 Homo sapiens sprouty homolog 3 (Drosophila) (SPRY3), mRNA [NM_005840] Homo sapiens zinc finger, MYM-type 6, mRNA (cDNA clone MGC:52473 IMAGE:5455214), complete cds. 2.029532 0.04148198 BC042172 BC042172 [BC042172] BX115782 Soares_testis_NHT Homo sapiens cDNA clone IMAGp998E224413, mRNA sequence 2.0295253 0.012424631 BX115782 BX115782 [BX115782] 2.0263426 0.038862385 AK025420 FLJ21767 Homo sapiens cDNA: FLJ21767 fis, clone COLF7237. [AK025420] 2.0256405 0.011262235 THC2537179 NC_006324 100K {Bovine adenovirus A} (exp=-1; wgp=0; cg=1), partial (4%) [THC2537179] 2.0225813 0.0243443 NM_173505 ANKRD29 Homo sapiens ankyrin repeat domain 29 (ANKRD29), mRNA [NM_173505] 2.022509 0.02828775 NM_000928 PLA2G1B Homo sapiens phospholipase A2, group IB (pancreas) (PLA2G1B), mRNA [NM_000928] AI382322 ta71d08.x1 Soares_total_fetus_Nb2HF8_9w Homo sapiens cDNA clone IMAGE:2049519 3', 2.022294 0.041823808 AI382322 AI382322 mRNA sequence [AI382322] Homo sapiens hypothetical protein LOC124976, mRNA (cDNA clone MGC:27061 IMAGE:4814561), 2.0217268 0.026190594 BC041772 SPNS2 complete cds. [BC041772] 2.0152671 0.03182184 NM_000119 EPB42 Homo sapiens erythrocyte membrane protein band 4.2 (EPB42), mRNA [NM_000119] Teashirt homolog 2 (Zinc finger protein 218) (Ovarian cancer-related protein 10-2) (OVC10-2). 2.0080714 0.04988736 TSHZ2 [Source:Uniprot/SWISSPROT;Acc:Q9NRE2] [ENST00000371497] 2.0067613 0.019015215 BX537816 BX537816 Homo sapiens mRNA; cDNA DKFZp686M03111 (from clone DKFZp686M03111) [BX537816] Homo sapiens serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 1.9851687 0.04543402 NM_016186 SERPINA10 (SERPINA10), mRNA [NM 016186] AL571926 Homo sapiens PLACENTA COT 25-NORMALIZED Homo sapiens cDNA clone CS0DI029YJ06 1.9834396 0.004378396 AL571926 AL571926 3-PRIME, mRNA sequence [AL571926] 1.9778026 0.010906613 NM_000562 C8A Homo sapiens complement component 8, alpha polypeptide (C8A), mRNA [NM_000562] Homo sapiens endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 6 (EDG6), 1.9765705 0.010191519 NM_003775 EDG6 mRNA [NM 003775] Homo sapiens Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse) (MOV10L1), mRNA 1.9763736 0.033950638 NM_018995 MOV10L1 [NM 018995] cell division cycle 37 homolog (S. cerevisiae)-like 1 [Source:RefSeq_peptide;Acc:NP_060383] 1.9759734 0.006124321 CDC37L1 [ENST00000381854] 1.9696972 0.029705757 NM_001002029 C4B Homo sapiens complement component 4B (Childo blood group) (C4B), mRNA [NM_001002029] 1.9672232 0.03986113 A_32_P136427 1.9652848 0.016397202 NM_032445 MEGF11 Homo sapiens multiple EGF-like-domains 11 (MEGF11), mRNA [NM_032445] 1.9639331 0.012398732 A_24_P110201 1.9572371 0.002727294 AK093351 FLJ36032 Homo sapiens cDNA FLJ36032 fis, clone TESTI2017069. [AK093351] 1.9566013 0.004362201 NM_020951 ZNF529 Homo sapiens zinc finger protein 529 (ZNF529), mRNA [NM_020951] 1.9499857 0.025917726 NM_022571 GPR135 Homo sapiens G protein-coupled receptor 135 (GPR135), mRNA [NM_022571] transmembrane and tetratricopeptide repeat containing 3 [Source:RefSeq_peptide;Acc:NP_861448] 1.9475771 0.037847936 TMTC3 [ENST00000266712] 1.9475387 0.004915683 NM_001558 IL10RA Homo sapiens interleukin 10 receptor, alpha (IL10RA), mRNA [NM_001558] 1.9414611 0.013902172 AK092602 C9orf94 Homo sapiens cDNA FLJ35283 fis, clone PROST2007528. [AK092602] 1.9350694 0.032290492 NM_054014 FKBP1A Homo sapiens FK506 binding protein 1A, 12kDa (FKBP1A), transcript variant 12A, mRNA [NM_054014] Homo sapiens F-box and WD repeat domain containing 7 (FBXW7), transcript variant 1, mRNA 1.9334502 0.02612309 NM_033632 FBXW7 [NM 033632] Homo sapiens sodium channel, voltage-gated, type V, alpha subunit (SCN5A), transcript variant 2, mRNA 1.9296336 0.03881812 NM_000335 SCN5A [NM 000335] 1.9275411 0.02154322 NM_002469 MYF6 Homo sapiens myogenic factor 6 (herculin) (MYF6), mRNA [NM_002469] 1.922609 0.031351104 NM_003311 PHLDA2 Homo sapiens pleckstrin homology-like domain, family A, member 2 (PHLDA2), mRNA [NM_003311] 1.9194071 0.005417815 NM_006757 TNNT3 Homo sapiens troponin T type 3 (skeletal, fast) (TNNT3), transcript variant 2, mRNA [NM_006757] 1.9175937 0.018013755 AB028966 TTC28 Homo sapiens mRNA for KIAA1043 protein, partial cds. [AB028966] Homo sapiens cAMP responsive element binding protein 5 (CREB5), transcript variant 1, mRNA 1.9152203 0.029109107 NM_182898 CREB5 [NM 182898] Homo sapiens retinoblastoma binding protein 6, mRNA (cDNA clone IMAGE:6214974), complete cds. 1.9149176 0.00293234 BC051317 RBBP6 [BC051317] 1.9103231 0.013818165 NM_016270 KLF2 Homo sapiens Kruppel-like factor 2 (lung) (KLF2), mRNA [NM_016270] 1.9076784 0.010862998 BC035518 BC035518 Homo sapiens, clone IMAGE:4214654, mRNA. [BC035518] 1.9051527 0.015017777 DNHD1 dynein heavy chain domain 1 [Source:RefSeq_peptide;Acc:NP_653267] [ENST00000354346] 1.9030348 0.009830037 AW961597 AW961597 EST373669 MAGE resequences, MAGG Homo sapiens cDNA, mRNA sequence [AW961597] 1.9011463 0.027406638 NM_002256 KISS1 Homo sapiens KiSS-1 metastasis-suppressor (KISS1), mRNA [NM_002256] Homo sapiens solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 (SLC25A25), 1.8977338 6.80E-05 NM_001006641 SLC25A25 nuclear gene encoding mitochondrial protein, transcript variant 2, mRNA [NM_001006641] 1.8975707 0.002778842 NM_002246 KCNK3 Homo sapiens potassium channel, subfamily K, member 3 (KCNK3), mRNA [NM_002246] Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 1.8933365 0.006471669 CD274 homolog 1) (B7-H1) (CD274 antigen). [Source:Uniprot/SWISSPROT;Acc:Q9NZQ7] [ENST00000381577] 1.887021 0.009000869 NM_000608 ORM2 Homo sapiens orosomucoid 2 (ORM2), mRNA [NM_000608] Q2NUU5_SODGM (Q2NUU5) Glutamate-aspartate ABC transporter ATP-binding component GltL, partial 1.8859435 0.002375605 THC2533854 (7%) [THC2533854] 1.8785616 0.047317963 A_32_P91156 1.8727052 0.007017562 NM_173544 FAM129C Homo sapiens family with sequence similarity 129, member C (FAM129C), mRNA [NM_173544] AA449494 zx08h11.s1 Soares_total_fetus_Nb2HF8_9w Homo sapiens cDNA clone IMAGE:785925 3' 1.8678654 0.03715264 AA449494 AA449494 similar to gb:U15981 ADRENAL SPECIFIC 30 KD PROTEIN (HUMAN);, mRNA sequence [AA449494] 1.8667209 0.012843604 NM_032041 NCALD Homo sapiens neurocalcin delta (NCALD), transcript variant 8, mRNA [NM_032041] 1.859818 0.022225518 THC2655810 1.8590344 0.035238978 AK057177 L3MBTL2 Homo sapiens cDNA FLJ32615 fis, clone STOMA2000148. [AK057177] Homo sapiens serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 1.8576896 0.01240848 NM_001756 SERPINA6 (SERPINA6), mRNA [NM 001756] 1.8560781 0.047234785 BE218351 BE218351 hv37e08.x1 NCI_CGAP_Lu24 Homo sapiens cDNA clone IMAGE:3175622 3', mRNA sequence [BE218351] 1.8547449 0.045395326 NM_005063 SCD Homo sapiens stearoyl-CoA desaturase (delta-9-desaturase) (SCD), mRNA [NM_005063] 1.8521574 0.048637632 LRRC38 Leucine rich repeat containing 38. [Source:Uniprot/SPTREMBL;Acc:Q5VT99] [ENST00000376085] full-length cDNA clone CS0DI062YF05 of Placenta Cot 25-normalized of Homo sapiens (human) 1.851947 0.0378405 CR601496 CR601496 [CR601496] 1.845974 0.04373389 NM_002984 CCL4 Homo sapiens chemokine (C-C motif) ligand 4 (CCL4), transcript variant 1, mRNA [NM_002984] 1.8423381 0.021540873 THC2534212 O60448_HUMAN (O60448) Neuronal thread protein AD7c-NTP, partial (15%) [THC2534212] 1.8345096 0.025584027 NM_001773 CD34 Homo sapiens CD34 molecule (CD34), transcript variant 2, mRNA [NM_001773] 1.834108 0.001963864 BC007817 BC007817 Homo sapiens cDNA clone IMAGE:4300770, complete cds. [BC007817] 1.8312197 0.011126519 NM_024711 GIMAP6 Homo sapiens GTPase, IMAP family member 6 (GIMAP6), transcript variant 1, mRNA [NM_024711] 1.8255978 0.006191345 NM_004473 FOXE1 Homo sapiens forkhead box E1 (thyroid transcription factor 2) (FOXE1), mRNA [NM_004473] Homo sapiens keratinocyte growth factor-like protein 1, mRNA (cDNA clone MGC:126891 1.8231363 0.030710727 BC101842 KGFLP1 IMAGE:8069348), complete cds. [BC101842] 1.817984 0.03914759 BX641014 BX641014 Homo sapiens mRNA; cDNA DKFZp686I19109 (from clone DKFZp686I19109) [BX641014] Homo sapiens elastin (supravalvular aortic stenosis, Williams-Beuren syndrome) (ELN), transcript variant 1, 1.8111835 0.04584883 NM_000501 ELN mRNA [NM 000501] 1.8094867 0.028789796 AK056150 LOC149478 Homo sapiens cDNA FLJ31588 fis, clone NT2RI2002252. [AK056150] 1.8067406 0.039784864 NR_001543 TTTY14 Homo sapiens testis-specific transcript, Y-linked 14 (TTTY14) on chromosome Y [NR_001543] 1.8035774 0.014961917 NM_001048210 CLCC1 Homo sapiens chloride channel CLIC-like 1 (CLCC1), transcript variant 1, mRNA [NM_001048210] 1.8032118 0.006983229 NM_207380 FLJ43339 Homo sapiens FLJ43339 protein (FLJ43339), mRNA [NM_207380] 1.8011448 0.042178266 AK092751 LOC286254 Homo sapiens cDNA FLJ35432 fis, clone SMINT2002311. [AK092751] AI467970 tj79c03.x1 Soares_NSF_F8_9W_OT_PA_P_S1 Homo sapiens cDNA clone IMAGE:2147716 3', 1.8007735 0.035881147 AI467970 AI467970 mRNA sequence [AI467970] 1.8001326 0.017591953 THC2585656 Q6NVT1_XENTR (Q6NVT1) RNA binding motif protein 25, partial (7%) [THC2585656] 1.7989504 0.010853662 NM_174910 TCTE3 Homo sapiens t-complex-associated-testis-expressed 3 (TCTE3), mRNA [NM_174910] 1.7920356 0.03146068 THC2633136 Q9F8M7_CARHY (Q9F8M7) DTDP-glucose 4,6-dehydratase (Fragment), partial (11%) [THC2702655] 1.791489 0.01246392 NM_138344 C14orf152 Homo sapiens chromosome 14 open reading frame 152 (C14orf152), mRNA [NM_138344] 1.7894716 0.005710498 AK123235 CCDC108 Homo sapiens cDNA FLJ41241 fis, clone BRAMY2032242. [AK123235] 1.7876201 0.04795278 NM_003395 WNT9A Homo sapiens wingless-type MMTV integration site family, member 9A (WNT9A), mRNA [NM_003395] 1.7852181 0.015308782 NR_003260 C15orf51 Homo sapiens chromosome 15 open reading frame 51 (C15orf51) on chromosome 15 [NR_003260] 1.7784137 0.038935814 NM_024548 LRRIQ2 Homo sapiens leucine-rich repeats and IQ motif containing 2 (LRRIQ2), mRNA [NM_024548] Homo sapiens Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 (RAPH1), transcript 1.7746294 0.017855264 NM_213589 RAPH1 variant 1, mRNA [NM 213589] 1.7739753 0.04743241 A_32_P21742 1.7595891 0.003711346 NM_138445 GPR146 Homo sapiens G protein-coupled receptor 146 (GPR146), mRNA [NM_138445] 1.7591758 0.026130384 NM_001016 RPS12 Homo sapiens ribosomal protein S12 (RPS12), mRNA [NM_001016] 1.757058 0.04389338 NM_194072 HILS1 Homo sapiens histone linker H1 domain, spermatid-specific 1 (HILS1), mRNA [NM_194072] 1.7553954 0.043309186 ENST00000390539 Immunoglobulin heavy chain C gene segment [Source:IMGT/GENE_DB;Acc:IGHA2] [ENST00000390539]

1.7538004 0.027313875 AW844496 AW844496 AW844496 RC2-CN0051-210200-015-f06 CN0051 Homo sapiens cDNA, mRNA sequence [AW844496] 1.7504541 0.033467747 AK021570 AK021570 Homo sapiens cDNA FLJ11508 fis, clone HEMBA1002162. [AK021570] 1.7495382 0.049953077 AK123333 AK123333 Homo sapiens cDNA FLJ41339 fis, clone BRASW1000053. [AK123333] 1.7450746 0.024409225 NM_198488 FAM83H Homo sapiens family with sequence similarity 83, member H (FAM83H), mRNA [NM_198488] 1.740464 0.004870367 NM_181722 LOC285908 Homo sapiens hypothetical protein LOC285908 (LOC285908), mRNA [NM_181722] 1.735285 0.048536215 NM_004653 JARID1D Homo sapiens jumonji, AT rich interactive domain 1D (JARID1D), mRNA [NM_004653] 1.7345817 0.016509492 NM_019594 LRRC8A Homo sapiens leucine rich repeat containing 8 family, member A (LRRC8A), mRNA [NM_019594] 1.7344598 0.043063343 NM_003107 SOX4 Homo sapiens SRY (sex determining region Y)-box 4 (SOX4), mRNA [NM_003107] Homo sapiens tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 1, 1.7312031 0.001256874 NM_003842 TNFRSF10B mRNA [NM 003842] 1.7304837 2.87E-04 A_32_P17615 1.7257204 0.030261122 D80006 D80006 Homo sapiens KIAA0184 mRNA, complete cds. [D80006] 1.7189348 0.01061953 NM_001003 RPLP1 Homo sapiens ribosomal protein, large, P1 (RPLP1), transcript variant 1, mRNA [NM_001003] 1.7168962 0.0201128 A_32_P82179 Homo sapiens cDNA FLJ38180 fis, clone FCBBF1000121, weakly similar to Homo sapiens mRNA for SHPS- 1.7156781 0.004780497 AK095499 SIRPB2 1. [AK095499] 1.7156272 0.002351252 NM_139247 ADCY4 Homo sapiens adenylate cyclase 4 (ADCY4), mRNA [NM_139247] 1.7106552 0.028636456 NM_005143 HP Homo sapiens haptoglobin (HP), mRNA [NM_005143] 1.7094839 0.042975128 NM_019102 HOXA5 Homo sapiens homeobox A5 (HOXA5), mRNA [NM_019102] 1.7088653 0.017240958 NM_153270 KLHL34 Homo sapiens kelch-like 34 (Drosophila) (KLHL34), mRNA [NM_153270] 1.706193 0.047843874 NM_033118 MYLK2 Homo sapiens myosin light chain kinase 2, skeletal muscle (MYLK2), mRNA [NM_033118] 1.7045982 0.03974307 AK126415 AK126415 Homo sapiens cDNA FLJ44451 fis, clone UTERU2023039. [AK126415] Eukaryotic translation initiation factor 4E-binding protein 2 (4E-BP2) (eIF4E-binding protein 2). 1.7028922 0.046886295 EIF4EBP2 [Source:Uniprot/SWISSPROT;Acc:Q13542] [ENST00000373218] 1.7023562 0.010812961 NM_004405 DLX2 Homo sapiens distal-less homeobox 2 (DLX2), mRNA [NM_004405] 1.6988311 0.02237345 NM_001052 SSTR4 Homo sapiens 4 (SSTR4), mRNA [NM_001052] 1.6972547 0.014907473 NM_005282 GPR4 Homo sapiens G protein-coupled receptor 4 (GPR4), mRNA [NM_005282] 1.6964562 0.030848164 NM_182492 LRP5L Homo sapiens low density lipoprotein receptor-related protein 5-like (LRP5L), mRNA [NM_182492] 1.695041 0.03903149 NM_000875 IGF1R Homo sapiens insulin-like growth factor 1 receptor (IGF1R), mRNA [NM_000875] Homo sapiens solute carrier organic anion transporter family, member 5A1 (SLCO5A1), mRNA 1.6946502 0.026165841 NM_030958 SLCO5A1 [NM 030958] 1.6928847 0.002281669 AF158555 GLS Homo sapiens C mRNA, complete cds. [AF158555] wj89h07.x1 NCI_CGAP_Lym12 Homo sapiens cDNA clone IMAGE:2410045 3', mRNA sequence 1.6892753 0.016151609 AI818976 AI818976 [AI818976] 1.6888279 0.046212718 NM_020064 BARHL1 Homo sapiens BarH-like 1 (Drosophila) (BARHL1), mRNA [NM_020064] 1.6877172 0.009862184 BC020539 BC020539 Homo sapiens, clone IMAGE:3048919, mRNA, partial cds. [BC020539] 1.6849172 0.04905254 XM_928321 LOC645277 PREDICTED: Homo sapiens hypothetical LOC645277 (LOC645277), mRNA [XM_928321] 1.6813877 0.02447961 NM_025079 ZC3H12A Homo sapiens zinc finger CCCH-type containing 12A (ZC3H12A), mRNA [NM_025079] 1.6808829 0.04210438 NM_025160 WDR26 Homo sapiens WD repeat domain 26 (WDR26), mRNA [NM_025160] 1.6801993 0.030098079 NM_032854 CORO6 Homo sapiens coronin 6 (CORO6), mRNA [NM_032854] 1.6796438 0.04218537 NM_006123 IDS Homo sapiens iduronate 2-sulfatase (Hunter syndrome) (IDS), transcript variant 2, mRNA [NM_006123] Homo sapiens keratin associated protein 2-4, mRNA (cDNA clone MGC:74790 IMAGE:3907481), complete 1.6755339 0.007392633 BC063625 KRTAP2-4 cds. [BC063625] full-length cDNA clone CS0DI026YO05 of Placenta Cot 25-normalized of Homo sapiens (human) 1.6751605 0.015324569 CR610759 CR610759 [CR610759] CB853344 UI-CF-FN0-agc-a-02-0-UI.s1 UI-CF-FN0 Homo sapiens cDNA clone UI-CF-FN0-agc-a-02-0-UI 1.6747407 0.011797887 CB853344 CB853344 3', mRNA sequence [CB853344] Homo sapiens cDNA FLJ12257 fis, clone MAMMA1001501, highly similar to CALPAIN 1, LARGE 1.67473 0.03613831 AK022319 CAPN1 [CATALYTIC] SUBUNIT (EC 3.4.22.17). [AK022319] 1.6730983 0.043259554 NM_004343 CALR Homo sapiens calreticulin (CALR), mRNA [NM_004343] 1.6708127 0.022872059 NM_182924 MICALL2 Homo sapiens MICAL-like 2 (MICALL2), transcript variant 1, mRNA [NM_182924] 1.6700557 0.003890004 NM_030641 APOL6 Homo sapiens apolipoprotein L, 6 (APOL6), mRNA [NM_030641] 1.6684958 0.01684841 NM_001003 RPLP1 Homo sapiens ribosomal protein, large, P1 (RPLP1), transcript variant 1, mRNA [NM_001003] Homo sapiens paired immunoglobin-like type 2 receptor beta (PILRB), transcript variant 1, mRNA 1.6682936 0.040917743 NM_013440 PILRB [NM 013440] 1.667845 0.026163943 NR_002556 LOC388242 Homo sapiens LOC112869 pseudogene (LOC388242) on chromosome 16 [NR_002556] 1.6664557 0.0241086 NM_002558 P2RX1 Homo sapiens P2X, ligand-gated ion channel, 1 (P2RX1), mRNA [NM_002558] 1.6656303 0.044835825 NM_080429 AQP10 Homo sapiens aquaporin 10 (AQP10), mRNA [NM_080429] 1.6602826 0.008361811 NM_018976 SLC38A2 Homo sapiens solute carrier family 38, member 2 (SLC38A2), mRNA [NM_018976] 1.6506845 0.03655904 NM_002526 NT5E Homo sapiens 5'-, ecto (CD73) (NT5E), mRNA [NM_002526] 1.6493913 0.025024053 A_24_P413286

1.6424643 0.005970271 NM_182518 C1orf84 Homo sapiens chromosome 1 open reading frame 84 (C1orf84), transcript variant 3, mRNA [NM_182518] Homo sapiens protein phosphatase 1, catalytic subunit, beta isoform (PPP1CB), transcript variant 1, mRNA 1.6416445 0.022042088 NM_002709 PPP1CB [NM 002709] 1.6370158 0.021069076 NM_012415 RAD54B Homo sapiens RAD54 homolog B (S. cerevisiae) (RAD54B), mRNA [NM_012415] Homo sapiens ferredoxin reductase (FDXR), nuclear gene encoding mitochondrial protein, transcript variant 1.6350517 0.019109901 NM_024417 FDXR 1, mRNA [NM 024417] 1.6342664 0.007476933 THC2636529 1.6330466 0.00811404 NM_024756 MMRN2 Homo sapiens multimerin 2 (MMRN2), mRNA [NM_024756] Homo sapiens trafficking protein particle complex 2 (TRAPPC2), transcript variant 1, mRNA 1.6326889 0.048378333 NM_001011658 TRAPPC2 [NM 001011658] 1.6321673 0.035307977 NM_153021 PLB1 Homo sapiens phospholipase B1 (PLB1), mRNA [NM_153021] Homo sapiens glutamate decarboxylase 1 (brain, 67kDa) (GAD1), transcript variant GAD25, mRNA 1.6304048 0.024683 NM_013445 GAD1 [NM 013445] 1.6288373 0.022204023 CR992331 CR992331 CR992331 RZPD no.9016 Homo sapiens cDNA clone RZPDp9016A0141 5', mRNA sequence [CR992331] 1.6281277 0.036017574 AK127156 AK127156 Homo sapiens cDNA FLJ45218 fis, clone BRCAN2019653. [AK127156] 1.6252023 0.021902267 NM_002429 MMP19 Homo sapiens matrix metallopeptidase 19 (MMP19), transcript variant 1, mRNA [NM_002429] 1.624552 0.042492453 BC030106 BC030106 Homo sapiens cDNA clone IMAGE:4797878. [BC030106] 1.6216363 0.029347088 NM_007149 ZNF184 Homo sapiens zinc finger protein 184 (ZNF184), mRNA [NM_007149] 1.6210485 0.046635814 AK024188 FLJ14126 Homo sapiens cDNA FLJ14126 fis, clone MAMMA1002571. [AK024188] 1.6209352 0.023240913 AF318367 C9orf86 Homo sapiens pp8875 mRNA, complete cds. [AF318367] 1.620036 0.048339147 NM_001312 CRIP2 Homo sapiens cysteine-rich protein 2 (CRIP2), mRNA [NM_001312] 1.618863 6.06E-04 NM_144652 LETM2 Homo sapiens leucine zipper-EF-hand containing transmembrane protein 2 (LETM2), mRNA [NM_144652] 1.6174843 0.03281957 NM_006646 WASF3 Homo sapiens WAS protein family, member 3 (WASF3), mRNA [NM_006646] Homo sapiens solute carrier family 22 (organic anion transporter), member 7 (SLC22A7), transcript variant 2, 1.6172472 0.001035717 NM_153320 SLC22A7 mRNA [NM 153320] 1.6130869 2.54E-04 NM_178497 C4orf26 Homo sapiens chromosome 4 open reading frame 26 (C4orf26), mRNA [NM_178497] 1.610212 0.041174408 NM_033161 SURF4 Homo sapiens surfeit 4 (SURF4), mRNA [NM_033161] BX092067 Soares infant brain 1NIB Homo sapiens cDNA clone IMAGp998C01145 ; IMAGE:28678, mRNA 1.6090692 0.039959762 BX092067 BX092067 sequence [BX092067] 1.6074083 0.038938113 AB046765 KIAA1545 Homo sapiens mRNA for KIAA1545 protein, partial cds. [AB046765] 1.6056621 0.018439546 AB051442 KIAA1655 Homo sapiens mRNA for KIAA1655 protein, partial cds. [AB051442] 1.6039194 0.013564572 THC2719076 1.60113 0.02368098 NM_005358 LMO7 Homo sapiens LIM domain 7 (LMO7), mRNA [NM_005358] 1.6003404 0.007236068 BC037918 BC037918 Homo sapiens cDNA clone IMAGE:5278070. [BC037918] Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine 1.6002852 0.044779368 ENST00000378179 protein kinase) (Lin-2 homolog). [Source:Uniprot/SWISSPROT;Acc:O14936] [ENST00000378179] 1.5997366 0.03782983 NM_021999 ITM2B Homo sapiens integral membrane protein 2B (ITM2B), mRNA [NM_021999] 1.5993617 0.049447007 NM_004054 C3AR1 Homo sapiens complement component 3a receptor 1 (C3AR1), mRNA [NM_004054] Homo sapiens UDP-Gal:betaGlcNAc beta 1,4- , polypeptide 1 (B4GALT1), mRNA 1.5984348 0.026195219 NM_001497 B4GALT1 [NM 001497] 1.5965885 0.028283842 NM_020939 CPNE5 Homo sapiens copine V (CPNE5), mRNA [NM_020939] 1.5949525 0.046608552 NM_004712 HGS Homo sapiens hepatocyte growth factor-regulated tyrosine kinase substrate (HGS), mRNA [NM_004712] 1.5935082 0.032447178 NM_001039464 C1orf175 Homo sapiens chromosome 1 open reading frame 175 (C1orf175), mRNA [NM_001039464] BX102314 BX102314 Soares pineal gland 3NbHPG Homo sapiens cDNA clone IMAGp998D02888 ; 1.5932659 0.006484926 BX102314 BX102314 IMAGE:383185, mRNA sequence [BX102314] 1.5910925 0.029848225 AK094877 CXorf36 Homo sapiens cDNA FLJ37558 fis, clone BRCOC1000087. [AK094877] 1.5903178 0.039249126 AK092305 RP11-262H14.4 Homo sapiens cDNA FLJ34986 fis, clone OCBBF2010945. [AK092305] 1.5902946 0.003077388 NM_052896 CSMD2 Homo sapiens CUB and Sushi multiple domains 2 (CSMD2), mRNA [NM_052896] 1.587281 0.019765884 NM_201525 GPR56 Homo sapiens G protein-coupled receptor 56 (GPR56), transcript variant 3, mRNA [NM_201525] 1.5840185 0.00384463 NM_000835 GRIN2C Homo sapiens glutamate receptor, ionotropic, N-methyl D-aspartate 2C (GRIN2C), mRNA [NM_000835] 1.5837339 0.01989325 ENST00000367932 Homo sapiens cDNA FLJ43132 fis, clone CTONG3005813. [AK125122] PREDICTED: Homo sapiens similar to SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski- 1.582765 0.043167103 XR_019381 LOC652549 interacting protein) (Nuclear receptor coactivator NCoA-62) (LOC652549), mRNA [XR 019381] 1.5816047 0.047651276 CR749547 CR749547 Homo sapiens mRNA; cDNA DKFZp686J17110 (from clone DKFZp686J17110) [CR749547] 1.5751396 0.013558196 L79989 SP100 Homo sapiens nuclear autoantigen mRNA, partial cds; alternatively spliced. [L79989] 1.5714601 0.0023107 NM_138961 ESAM Homo sapiens endothelial cell adhesion molecule (ESAM), mRNA [NM_138961] Homo sapiens pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1.5710753 0.010865863 NM_001001974 PLEKHA1 1 (PLEKHA1), transcript variant 2, mRNA [NM 001001974] 1.5705619 0.028610501 A_23_P16496 1.5687801 0.026003454 NM_000448 RAG1 Homo sapiens recombination activating gene 1 (RAG1), mRNA [NM_000448] Human mRNA for immunoglobulin lambda variable region corresponding to NEW protein of V lambda 1.5674465 0.04770068 X01147 X01147 subgroup I. [X01147] 1.5674194 0.045431904 NM_001011880 LOC497190 Homo sapiens secretory protein LOC497190 (LOC497190), mRNA [NM_001011880] 1.5630292 0.02269001 AF087999 AF087999 Homo sapiens full length insert cDNA clone YX44E03. [AF087999] 1.5621332 0.014056187 NM_145314 C10orf49 Homo sapiens chromosome 10 open reading frame 49 (C10orf49), mRNA [NM_145314] 1.5617471 0.002103732 NM_001040455 SIDT2 Homo sapiens SID1 transmembrane family, member 2 (SIDT2), mRNA [NM_001040455] 1.5593982 0.040224373 NM_178332 GNRH2 Homo sapiens gonadotropin-releasing hormone 2 (GNRH2), transcript variant 2, mRNA [NM_178332] Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 (DDX17), transcript variant 1, mRNA 1.5578091 0.008639227 NM_006386 DDX17 [NM 006386] Guanylate kinase (EC 2.7.4.8) (GMP kinase). [Source:Uniprot/SWISSPROT;Acc:Q16774] 1.5563916 0.00847961 GUK1 [ENST00000366716] 1.5535401 0.015844928 BC067908 BC067908 Homo sapiens cDNA clone IMAGE:30332316. [BC067908] 1.552799 0.016924376 NM_020982 CLDN9 Homo sapiens claudin 9 (CLDN9), mRNA [NM_020982] Homo sapiens G-protein signalling modulator 1 (AGS3-like, C. elegans), mRNA (cDNA clone 1.5479918 0.026132742 BC048343 GPSM1 IMAGE:5242824), complete cds. [BC048343] 1.5457718 0.013999537 NM_206920 MAMDC4 Homo sapiens MAM domain containing 4 (MAMDC4), mRNA [NM_206920] 1.544607 3.14E-04 NM_022452 FBRS Homo sapiens fibrosin 1 (FBS1), mRNA [NM_022452] Probable RNA-binding protein 19 (RNA-binding motif protein 19). 1.5442845 0.041807406 RBM19 [Source:Uniprot/SWISSPROT;Acc:Q9Y4C8] [ENST00000261741] 1.5377824 0.045315 NM_020439 CAMK1G Homo sapiens calcium/calmodulin-dependent protein kinase IG (CAMK1G), mRNA [NM_020439] 1.5366858 0.002509773 NM_014475 DHDH Homo sapiens dihydrodiol dehydrogenase (dimeric) (DHDH), mRNA [NM_014475] 1.5341439 0.032359213 NM_000984 RPL23A Homo sapiens ribosomal protein L23a (RPL23A), mRNA [NM_000984] Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII 1.5337579 0.039271895 TCEB3 p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit). [Source:Uniprot/SWISSPROT;Acc:Q14241] [ENST00000374536] Homo sapiens calcium channel, voltage-dependent, L type, alpha 1C subunit (CACNA1C), mRNA 1.5324205 0.009527643 NM_000719 CACNA1C [NM 000719] 1.5316381 0.03076274 NM_014734 KIAA0247 Homo sapiens KIAA0247 (KIAA0247), mRNA [NM_014734] N48043 yy23h06.r1 Soares 2NbHM Homo sapiens cDNA clone IMAGE:272123 5' similar to 1.5309057 0.031762276 N48043 N48043 gb:X04665 cds1 THROMBOSPONDIN 1 PRECURSOR (HUMAN);, mRNA sequence [N48043] 1.5273461 0.00604142 AK024224 AK024224 Homo sapiens cDNA FLJ14162 fis, clone NT2RM4002504. [AK024224] 1.5267011 0.033388957 NM_018837 SULF2 Homo sapiens sulfatase 2 (SULF2), transcript variant 1, mRNA [NM_018837] 1.5253386 0.026325777 NM_004603 STX1A Homo sapiens syntaxin 1A (brain) (STX1A), mRNA [NM_004603] 1.5218823 0.010258979 NM_153261 TMEM188 Homo sapiens chromosome 16 open reading frame 69 (C16orf69), mRNA [NM_153261] Homo sapiens GTPase activating protein (SH3 domain) binding protein 2 (G3BP2), transcript variant 1, 1.5218211 0.024881773 NM_203505 G3BP2 mRNA [NM 203505] Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6- 1.5207974 0.024429949 ATF6 alpha). [Source:Uniprot/SWISSPROT;Acc:P18850] [ENST00000367942] 1.5203297 0.01801944 NM_145003 TSNARE1 Homo sapiens t-SNARE domain containing 1 (TSNARE1), mRNA [NM_145003] 1.5188183 0.009391364 NM_152346 SLC43A2 Homo sapiens solute carrier family 43, member 2 (SLC43A2), mRNA [NM_152346] 1.5175822 0.041639756 NM_173552 C3orf58 Homo sapiens chromosome 3 open reading frame 58 (C3orf58), mRNA [NM_173552] 1.5174295 0.046000756 NM_032258 TBC1D3 Homo sapiens TBC1 domain family, member 3 (TBC1D3), mRNA [NM_032258] 1.5172755 0.00578436 NM_017634 KCTD9 Homo sapiens potassium channel tetramerisation domain containing 9 (KCTD9), mRNA [NM_017634] Homo sapiens solute carrier family 9 (sodium/hydrogen exchanger), member 8 (SLC9A8), mRNA 1.5169302 0.03588553 NM_015266 SLC9A8 [NM 015266] Homo sapiens mitochondrial ribosomal protein S6 (MRPS6), nuclear gene encoding mitochondrial protein, 1.5161575 0.03016709 NM_032476 MRPS6 mRNA [NM 032476] 1.514855 0.0182975 NM_031289 GSG1 Homo sapiens germ cell associated 1 (GSG1), transcript variant 1, mRNA [NM_031289] Homo sapiens MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (MFNG), mRNA 1.514416 0.03388588 NM_002405 MFNG [NM 002405] 1.5141319 0.013426951 NM_198490 RAB43 Homo sapiens RAB43, member RAS oncogene family (RAB43), mRNA [NM_198490] Homo sapiens solute carrier family 12 (potassium/chloride transporters), member 7 (SLC12A7), mRNA 1.512532 0.005487286 NM_006598 SLC12A7 [NM 006598] 1.5116532 0.023924503 XR_017750 NANOS3 PREDICTED: Homo sapiens nanos homolog 3 (Drosophila) (NANOS3), misc RNA [XR_017750] Homo sapiens killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 (KIR2DL2), 1.5114417 0.048088938 NM_014219 KIR2DL2 mRNA [NM 014219] 1.5107133 0.005685538 NM_004603 STX1A Homo sapiens syntaxin 1A (brain) (STX1A), mRNA [NM_004603] 1.5105599 0.035038766 NM_000372 TYR Homo sapiens (oculocutaneous IA) (TYR), mRNA [NM_000372] 1.5098232 0.047994394 CR936662 ZNF284 Homo sapiens mRNA; cDNA DKFZp781F1775 (from clone DKFZp781F1775). [CR936662] 1.5086684 0.02176435 NM_001733 C1R Homo sapiens complement component 1, r subcomponent (C1R), mRNA [NM_001733] 1.5082115 0.007971683 NM_014922 NLRP1 Homo sapiens NLR family, pyrin domain containing 1 (NLRP1), transcript variant 2, mRNA [NM_014922] 1.50539 0.033069152 NM_017622 C17orf59 Homo sapiens chromosome 17 open reading frame 59 (C17orf59), mRNA [NM_017622] 1.5024631 0.016716236 NM_018487 TMEM176A Homo sapiens transmembrane protein 176A (TMEM176A), mRNA [NM_018487] 1.5020574 0.034094714 AK054965 FLJ30403 Homo sapiens cDNA FLJ30403 fis, clone BRACE2008480. [AK054965] Homo sapiens potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 1.5016257 0.01941561 NM_002250 KCNN4 (KCNN4), mRNA [NM 002250] 1.5004832 0.04701125 DA234975 DA234975 DA234975 BRAWH3 Homo sapiens cDNA clone BRAWH3031305 5', mRNA sequence [DA234975] Homo sapiens family with sequence similarity 102, member A (FAM102A), transcript variant 2, mRNA 1.5003477 0.043010138 NM_203305 FAM102A [NM 203305] 1.4998286 0.034045234 NM_032561 Homo sapiens chromosome 22 open reading frame 23 (C22orf23), mRNA [NM_032561] 1.4997092 0.041903112 NM_014994 MAPKBP1 Homo sapiens mitogen activated protein kinase binding protein 1 (MAPKBP1), mRNA [NM_014994] 1.4982526 4.38E-04 NM_024598 C16orf57 Homo sapiens chromosome 16 open reading frame 57 (C16orf57), mRNA [NM_024598] 1.4978662 0.002121757 NM_007110 TEP1 Homo sapiens telomerase-associated protein 1 (TEP1), mRNA [NM_007110] Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta (NFKBIZ), 1.4974587 0.021214498 NM_031419 NFKBIZ transcript variant 1, mRNA [NM 031419] 1.4878078 0.017409155 A_23_P126328 1.4856846 0.024457974 NM_031958 KRTAP3-1 Homo sapiens keratin associated protein 3-1 (KRTAP3-1), mRNA [NM_031958] 1.4833711 0.04075791 NM_203297 TRIM7 Homo sapiens tripartite motif-containing 7 (TRIM7), transcript variant 2, mRNA [NM_203297] 1.4831924 0.019247672 NM_000256 MYBPC3 Homo sapiens myosin binding protein C, cardiac (MYBPC3), mRNA [NM_000256] 1.4822639 0.00394432 CR936791 KIAA0888 Homo sapiens mRNA; cDNA DKFZp781C2356 (from clone DKFZp781C2356). [CR936791] 1.4813173 0.03191683 CR598370 CR598370 full-length cDNA clone CS0DF003YI18 of Fetal brain of Homo sapiens (human) [CR598370] 1.4788492 0.028374068 NM_019089 HES2 Homo sapiens hairy and enhancer of split 2 (Drosophila) (HES2), mRNA [NM_019089] Homo sapiens solute carrier family 4, sodium bicarbonate cotransporter, member 7 (SLC4A7), mRNA 1.4773427 0.012024861 NM_003615 SLC4A7 [NM 003615] 1.4751457 0.02788251 NM_080680 COL11A2 Homo sapiens collagen, type XI, alpha 2 (COL11A2), transcript variant 1, mRNA [NM_080680] 1.4737792 0.047991656 NM_017645 FAM29A Homo sapiens family with sequence similarity 29, member A (FAM29A), mRNA [NM_017645] 1.47259 0.028605688 NM_014824 FCHSD2 Homo sapiens FCH and double SH3 domains 2 (FCHSD2), mRNA [NM_014824] Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 4 (GNB4), mRNA 1.4713308 0.019289192 NM_021629 GNB4 [NM 021629] 1.4690008 0.023668947 NM_005415 SLC20A1 Homo sapiens solute carrier family 20 (phosphate transporter), member 1 (SLC20A1), mRNA [NM_005415] 1.4674984 0.032167006 NM_000803 FOLR2 Homo sapiens folate receptor 2 (fetal) (FOLR2), mRNA [NM_000803] 1.4629769 0.020951286 NM_016343 CENPF Homo sapiens centromere protein F, 350/400ka (mitosin) (CENPF), mRNA [NM_016343] 1.4608878 0.024451409 NM_198490 RAB43 Homo sapiens RAB43, member RAS oncogene family (RAB43), mRNA [NM_198490] 1.4601753 0.038351845 NM_001284 AP3S1 Homo sapiens adaptor-related protein complex 3, sigma 1 subunit (AP3S1), mRNA [NM_001284] 1.4597692 0.002664697 A_24_P916338 1.459025 0.015400372 NM_030652 EGFL8 Homo sapiens EGF-like-domain, multiple 8 (EGFL8), mRNA [NM_030652] 1.45861 0.002716945 THC2686967 1.4558535 0.016414732 NM_021926 ALX4 Homo sapiens aristaless-like homeobox 4 (ALX4), mRNA [NM_021926] 1.4523985 0.037098896 THC2500237 CB027_HUMAN (Q580R0) Protein C2orf27, partial (79%) [THC2500237] 1.4507565 0.021031335 NM_030818 CCDC130 Homo sapiens coiled-coil domain containing 130 (CCDC130), mRNA [NM_030818] 1.4500895 0.04465865 BG007597 BG007597 BG007597 QV4-GN0250-281100-608-g10 GN0250 Homo sapiens cDNA, mRNA sequence [BG007597] 1.448788 0.044132955 L06610 L06610 Human rearranged immunoglobulin heavy chain (IGH@) gene, 5' end. [L06610] 1.4450519 0.038873296 NM_181659 NCOA3 Homo sapiens nuclear receptor coactivator 3 (NCOA3), transcript variant 1, mRNA [NM_181659] Homo sapiens ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease), mRNA (cDNA 1.4422758 0.041892584 BC111068 CLN3 clone MGC:102840 IMAGE:5764535), complete cds. [BC111068] 1.4393321 0.020548172 NM_006996 SLC19A2 Homo sapiens solute carrier family 19 (thiamine transporter), member 2 (SLC19A2), mRNA [NM_006996] Homo sapiens cDNA FLJ13765 fis, clone PLACE4000128, weakly similar to Mus musculus putative 1.4356062 0.027441926 AK023827 RUNDC2B transcription factor mRNA. [AK023827] Homo sapiens hypothetical protein MGC14425, mRNA (cDNA clone MGC:14425 IMAGE:4302902), 1.4353952 0.035144307 BC007866 MGC14425 complete cds. [BC007866] 1.432238 0.04369372 NM_017613 DONSON Homo sapiens downstream neighbor of SON (DONSON), mRNA [NM_017613] Homo sapiens transforming growth factor, beta receptor II (70/80kDa) (TGFBR2), transcript variant 1, mRNA 1.4305788 0.04727852 NM_001024847 TGFBR2 [NM 001024847] 1.4304737 0.04102263 NM_080863 ASB16 Homo sapiens ankyrin repeat and SOCS box-containing 16 (ASB16), mRNA [NM_080863] 1.4303548 0.023926722 THC2757602 1.4282801 0.048630882 NM_152287 ZNF276 Homo sapiens zinc finger protein 276 (ZNF276), mRNA [NM_152287] 1.4272614 0.0355749 AL833696 AL833696 Homo sapiens mRNA; cDNA DKFZp667D139 (from clone DKFZp667D139). [AL833696] 1.427109 0.048660055 NM_004152 OAZ1 Homo sapiens antizyme 1 (OAZ1), mRNA [NM_004152] 1.4268128 0.020254845 NM_014665 LRRC14 Homo sapiens leucine rich repeat containing 14 (LRRC14), mRNA [NM_014665] 1.426107 0.028288329 NM_002827 PTPN1 Homo sapiens protein tyrosine phosphatase, non-receptor type 1 (PTPN1), mRNA [NM_002827] 1.4255646 0.00501938 NM_198489 CCDC84 Homo sapiens coiled-coil domain containing 84 (CCDC84), mRNA [NM_198489] 1.4250304 0.017441392 NM_006177 NRL Homo sapiens neural retina leucine zipper (NRL), mRNA [NM_006177] 1.424712 4.84E-04 BC014395 BC014395 Homo sapiens, clone IMAGE:3029191, mRNA. [BC014395] Homo sapiens ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease), mRNA (cDNA 1.4242667 0.041188005 BC111068 CLN3 clone MGC:102840 IMAGE:5764535), complete cds. [BC111068] 1.423015 0.017615713 NM_012412 H2AFV Homo sapiens H2A histone family, member V (H2AFV), transcript variant 1, mRNA [NM_012412] 1.422382 0.028774595 NM_004152 OAZ1 Homo sapiens ornithine decarboxylase antizyme 1 (OAZ1), mRNA [NM_004152] 1.4185281 0.038203005 NM_005532 IFI27 Homo sapiens interferon, alpha-inducible protein 27 (IFI27), mRNA [NM_005532] 1.416414 0.010419366 NM_178443 URP2 Homo sapiens UNC-112 related protein 2 (URP2), transcript variant URP2LF, mRNA [NM_178443] 1.4164052 3.22E-04 NM_000327 ROM1 Homo sapiens retinal outer segment membrane protein 1 (ROM1), mRNA [NM_000327] 1.4148945 0.005494292 NM_173822 FAM126B Homo sapiens family with sequence similarity 126, member B (FAM126B), mRNA [NM_173822] 1.4140878 0.009258 NM_019612 IRGC Homo sapiens immunity-related GTPase family, cinema (IRGC), mRNA [NM_019612] 1.4104366 0.047910385 NM_002275 KRT15 Homo sapiens keratin 15 (KRT15), mRNA [NM_002275] Homo sapiens MAP kinase interacting serine/threonine kinase 2 (MKNK2), transcript variant 1, mRNA 1.4086182 0.045759894 NM_017572 MKNK2 [NM 017572] Homo sapiens cDNA FLJ38735 fis, clone KIDNE2010973, moderately similar to Mus musculus orphan 1.4085526 0.026803965 AK096054 SLC6A19 transporter isoform B9 (Xtrp2) mRNA. [AK096054] 1.4085475 0.037905242 NM_005430 WNT1 Homo sapiens wingless-type MMTV integration site family, member 1 (WNT1), mRNA [NM_005430]

1.4022346 0.028160028 NM_018700 TRIM36 Homo sapiens tripartite motif-containing 36 (TRIM36), transcript variant 1, mRNA [NM_018700] -1.4006915 0.023655096 AK001179 ANKIB1 Homo sapiens cDNA FLJ10317 fis, clone NT2RM2000452. [AK001179] -1.4007423 0.007790437 NM_003635 NDST2 Homo sapiens N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 (NDST2), mRNA [NM_003635] -1.4014877 0.02868933 A_24_P856176 -1.4049133 0.010452271 NM_003691 STK16 Homo sapiens serine/threonine kinase 16 (STK16), transcript variant 1, mRNA [NM_003691] -1.4065149 0.008403737 NM_032816 CCDC123 Homo sapiens coiled-coil domain containing 123 (CCDC123), mRNA [NM_032816] -1.4083058 0.04148832 AY629351 ZCCHC4 Homo sapiens DHHC domain-containing zinc finger protein mRNA, complete cds. [AY629351] -1.4109015 0.00778027 NM_152994 CCDC128 Homo sapiens coiled-coil domain containing 128 (CCDC128), mRNA [NM_152994] -1.4116188 0.029954216 BC006438 BC006438 Homo sapiens cDNA clone MGC:13162 IMAGE:3010103, complete cds. [BC006438] -1.4127924 0.012676571 NM_020433 JPH2 Homo sapiens junctophilin 2 (JPH2), transcript variant 1, mRNA [NM_020433] -1.412932 0.002069372 AL137342 AL137342 Homo sapiens mRNA; cDNA DKFZp761G1111 (from clone DKFZp761G1111). [AL137342] Homo sapiens regenerating islet-derived 1 beta (pancreatic stone protein, pancreatic thread protein) (REG1B), -1.4129831 0.030225039 NM_006507 REG1B mRNA [NM 006507] -1.4130832 0.043358956 NM_024077 SECISBP2 Homo sapiens SECIS binding protein 2 (SECISBP2), mRNA [NM_024077] -1.4142408 0.019202555 A_24_P375405 -1.416927 0.031433035 XR_018411 LOC390993 PREDICTED: Homo sapiens similar to 60S ribosomal protein L7a (LOC390993), mRNA [XR_018411] -1.422137 0.049311996 NM_000628 IL10RB Homo sapiens interleukin 10 receptor, beta (IL10RB), mRNA [NM_000628] Homo sapiens Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) (RTF1), mRNA -1.4221654 0.044749618 NM_015138 RTF1 [NM 015138] -1.4221839 0.003956608 NM_133375 DIS3L Homo sapiens DIS3 mitotic control homolog (S. cerevisiae)-like (DIS3L), mRNA [NM_133375] Homo sapiens mitochondrial ribosomal protein L24 (MRPL24), nuclear gene encoding mitochondrial protein, -1.4263382 0.03151185 NM_145729 MRPL24 transcript variant 1, mRNA [NM 145729] -1.4274658 0.011556063 M95923 ALOX15 Human 12-lipoxygenase mRNA, partial cds. [M95923] Homo sapiens hypothetical protein LOC202051, mRNA (cDNA clone MGC:57735 IMAGE:5751687), -1.4279492 0.002814655 BC050563 LOC202051 complete cds. [BC050563] -1.4280574 0.04617567 NM_018472 FAM45B Homo sapiens family with sequence similarity 45, member B (FAM45B), mRNA [NM_018472] -1.428697 0.001620585 XR_015921 LOC729279 PREDICTED: Homo sapiens hypothetical protein LOC729279 (LOC729279), mRNA [XR_015921] -1.4297343 0.0355677 NM_001080541 MGA Homo sapiens MAX gene associated (MGA), mRNA [NM_001080541] -1.4301324 0.038182322 AK129849 AK129849 Homo sapiens cDNA FLJ26339 fis, clone HRT02975. [AK129849] -1.4317479 0.035558857 NM_145259 ACVR1C Homo sapiens activin A receptor, type IC (ACVR1C), mRNA [NM_145259] -1.4320856 0.048963644 NM_014423 AFF4 Homo sapiens AF4/FMR2 family, member 4 (AFF4), mRNA [NM_014423] -1.4339613 0.02855792 BC006438 BC006438 Homo sapiens cDNA clone MGC:13162 IMAGE:3010103, complete cds. [BC006438] -1.4342197 0.018450366 BF931515 BF931515 BF931515 IL2-NT0202-141200-308-H03 NT0202 Homo sapiens cDNA, mRNA sequence [BF931515] -1.4348824 0.02128665 NM_022151 MOAP1 Homo sapiens modulator of apoptosis 1 (MOAP1), mRNA [NM_022151] -1.4349332 0.007855726 NM_003707 RUVBL1 Homo sapiens RuvB-like 1 (E. coli) (RUVBL1), mRNA [NM_003707] -1.4371047 0.031170305 NM_014669 NUP93 Homo sapiens nucleoporin 93kDa (NUP93), mRNA [NM_014669] -1.4378928 0.023382602 NM_004035 ACOX1 Homo sapiens acyl-Coenzyme A oxidase 1, palmitoyl (ACOX1), transcript variant 1, mRNA [NM_004035] -1.4410638 0.016375955 ENST00000335078 Homo sapiens reticulon 4 interacting protein 1 (RTN4IP1), nuclear gene encoding mitochondrial protein, -1.4432782 0.01650223 NM_032730 RTN4IP1 mRNA [NM 032730] -1.4450879 0.026463982 NM_004813 PEX16 Homo sapiens peroxisomal biogenesis factor 16 (PEX16), transcript variant 1, mRNA [NM_004813] Homo sapiens acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) (ACAT1), nuclear -1.4473238 0.016793396 NM_000019 ACAT1 gene encoding mitochondrial protein, mRNA [NM 000019] Homo sapiens ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1), -1.4507034 0.021717 NM_001419 ELAVL1 mRNA [NM 001419] -1.452041 1.77E-04 NM_003470 USP7 Homo sapiens ubiquitin specific peptidase 7 (herpes virus-associated) (USP7), mRNA [NM_003470] -1.4536829 0.01187907 THC2694422 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 19 (ADAMTS19), mRNA -1.4564656 0.031935494 NM_133638 ADAMTS19 [NM 133638] RNA-binding protein 27 (RNA-binding motif protein 27). [Source:Uniprot/SWISSPROT;Acc:Q9P2N5] -1.4575335 0.020495748 ENST00000265271 [ENST00000265271] Homo sapiens nuclear transcription factor, X-box binding 1 (NFX1), transcript variant 2, mRNA -1.4602407 0.045490682 NM_147133 NFX1 [NM 147133] -1.4634186 0.005246139 NM_016094 COMMD2 Homo sapiens COMM domain containing 2 (COMMD2), mRNA [NM_016094] -1.463701 0.04459607 NM_024949 WWC2 Homo sapiens WW and C2 domain containing 2 (WWC2), mRNA [NM_024949] -1.4639002 0.027149864 NM_024831 TGS1 Homo sapiens trimethylguanosine synthase homolog (S. cerevisiae) (TGS1), mRNA [NM_024831] Homo sapiens nudix (nucleoside diphosphate linked moiety X)-type motif 2 (NUDT2), transcript variant 1, -1.4683667 0.009836354 NM_001161 NUDT2 mRNA [NM 001161] -1.4716184 0.039293885 A_24_P307255 Homo sapiens gamma-aminobutyric acid (GABA) A receptor, beta 2 (GABRB2), transcript variant 2, mRNA -1.476234 0.002256925 NM_000813 GABRB2 [NM 000813] BC037545 poly(ADP-ribosyl)transferase {Homo sapiens} (exp=-1; wgp=0; cg=0), partial (24%) -1.4769132 0.002710071 THC2762149 [THC2762149] -1.4799545 0.028311506 NM_001043352 TPM3 Homo sapiens tropomyosin 3 (TPM3), transcript variant 3, mRNA [NM_001043352] -1.4806055 0.011835638 NM_001634 AMD1 Homo sapiens adenosylmethionine decarboxylase 1 (AMD1), transcript variant 1, mRNA [NM_001634] Homo sapiens v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) (RALB), -1.4846939 0.035226002 NM_002881 RALB mRNA [NM 002881] ALU2_HUMAN (P39189) Alu subfamily SB sequence contamination warning entry, partial (17%) -1.485682 0.012446423 THC2773066 [THC2773066] -1.488183 0.01987112 NM_000021 PSEN1 Homo sapiens presenilin 1 (Alzheimer disease 3) (PSEN1), mRNA [NM_000021] -1.4882842 0.030477475 NM_000367 TPMT Homo sapiens thiopurine S-methyltransferase (TPMT), mRNA [NM_000367] -1.497299 0.031578723 A_24_P204165 -1.4977043 0.045525596 AK097488 LOC728213 Homo sapiens cDNA FLJ40169 fis, clone TESTI2016583. [AK097488] -1.500013 0.04249197 A_24_P272886 -1.5004007 0.01930666 AF085896 LOC440288 Homo sapiens full length insert cDNA clone YQ05H10. [AF085896] -1.5021538 0.045704685 NM_016440 VRK3 Homo sapiens vaccinia related kinase 3 (VRK3), transcript variant 1, mRNA [NM_016440] -1.5024302 0.017581267 AK127048 AK127048 Homo sapiens cDNA FLJ45105 fis, clone BRAWH3033117. [AK127048] Homo sapiens protein kinase, cAMP-dependent, regulatory, type II, alpha (PRKAR2A), mRNA -1.5033945 0.01696851 NM_004157 PRKAR2A [NM 004157] -1.5041132 0.039138075 NM_019557 FAM54B Homo sapiens family with sequence similarity 54, member B (FAM54B), mRNA [NM_019557] -1.5044624 0.022175534 AK023557 AK023557 Homo sapiens cDNA FLJ13495 fis, clone PLACE1004425. [AK023557] -1.5047245 0.025731662 NM_003611 OFD1 Homo sapiens oral-facial-digital syndrome 1 (OFD1), mRNA [NM_003611] -1.5057851 0.011809668 ENST00000318301 -1.5063488 0.011142476 NM_130773 CNTNAP5 Homo sapiens contactin associated protein-like 5 (CNTNAP5), transcript variant 1, mRNA [NM_130773] ALU2_HUMAN (P39189) Alu subfamily SB sequence contamination warning entry, partial (6%) -1.50847 0.035151318 THC2741996 [THC2741996] BF593129 7o49h09.x1 NCI_CGAP_Kid11 Homo sapiens cDNA clone IMAGE:3577600 3', mRNA sequence -1.5106419 0.03354485 BF593129 BF593129 [BF593129] -1.512991 0.014894455 NM_032357 CCDC115 Homo sapiens coiled-coil domain containing 115 (CCDC115), mRNA [NM_032357] -1.5131754 0.035895783 ENST00000329536 Zinc finger protein 717. [Source:Uniprot/SPTREMBL;Acc:Q5XG89] [ENST00000329536] -1.5152014 0.034466926 A_24_P698376 -1.5165366 0.04998729 NM_005391 PDK3 Homo sapiens pyruvate dehydrogenase kinase, 3 (PDK3), mRNA [NM_005391] -1.5172921 3.20E-04 A_23_P13232 Homo sapiens hydroxyacyl-Coenzyme A dehydrogenase (HADH), nuclear gene encoding mitochondrial -1.5184293 0.021535525 NM_005327 HADH protein, mRNA [NM 005327] PREDICTED: Homo sapiens similar to Poly [ADP-ribose] polymerase 1 (PARP-1) (ADPRT) (NAD(+) ADP- -1.5211306 0.012262976 XR_019461 LOC649459 ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (LOC649459), mRNA [XR 019461] AI264747 qx54h07.x1 NCI_CGAP_Pan1 Homo sapiens cDNA clone IMAGE:2005213 3' similar to -1.522963 0.014965263 AI264747 AI264747 SW:NPL1_HUMAN P55209 NUCLEOSOME ASSEMBLY PROTEIN 1-LIKE 1 ;, mRNA sequence [AI264747] -1.527175 0.007674264 NM_015959 TXNDC14 Homo sapiens thioredoxin domain containing 14 (TXNDC14), mRNA [NM_015959] -1.5277843 0.028719496 NM_002086 GRB2 Homo sapiens growth factor receptor-bound protein 2 (GRB2), transcript variant 1, mRNA [NM_002086] -1.5287955 0.030391023 NM_052925 LENG8 Homo sapiens leukocyte receptor cluster (LRC) member 8 (LENG8), mRNA [NM_052925] -1.528881 0.03841036 NM_023077 C1orf163 Homo sapiens chromosome 1 open reading frame 163 (C1orf163), mRNA [NM_023077] -1.5308605 0.005023078 NM_015434 INTS7 Homo sapiens integrator complex subunit 7 (INTS7), mRNA [NM_015434] -1.5315994 0.017165694 NM_198554 THADA Homo sapiens thyroid adenoma associated (THADA), transcript variant 2, mRNA [NM_198554] -1.5331647 0.04371321 NM_001005861 RYK Homo sapiens RYK receptor-like tyrosine kinase (RYK), transcript variant 1, mRNA [NM_001005861]

-1.5352659 0.031573612 NM_178313 SPTBN1 Homo sapiens spectrin, beta, non-erythrocytic 1 (SPTBN1), transcript variant 2, mRNA [NM_178313] -1.5376006 0.013432997 NM_002957 RXRA Homo sapiens retinoid X receptor, alpha (RXRA), mRNA [NM_002957] Homo sapiens myeloid-associated differentiation marker (MYADM), transcript variant 2, mRNA -1.5382283 0.001169818 NM_138373 MYADM [NM 138373] -1.5419813 0.00698674 NM_003749 IRS2 Homo sapiens substrate 2 (IRS2), mRNA [NM_003749] -1.544509 0.011680148 NM_020240 CDC42SE2 Homo sapiens CDC42 small effector 2 (CDC42SE2), transcript variant 1, mRNA [NM_020240] -1.5462472 0.02990148 NM_033028 BBS4 Homo sapiens Bardet-Biedl syndrome 4 (BBS4), mRNA [NM_033028] -1.5487561 0.030517586 NM_006990 WASF2 Homo sapiens WAS protein family, member 2 (WASF2), mRNA [NM_006990] -1.5507971 0.036896657 BC014023 BC014023 Homo sapiens cDNA clone IMAGE:4309177, **** WARNING: chimeric clone ****. [BC014023] -1.5515563 0.0343833 NM_020920 CHD8 Homo sapiens chromodomain helicase DNA binding protein 8 (CHD8), mRNA [NM_020920] -1.5523897 0.031161383 BC079833 BC079833 Homo sapiens cDNA clone IMAGE:6271217. [BC079833] -1.5624179 0.03381001 NM_024719 GRTP1 Homo sapiens growth hormone regulated TBC protein 1 (GRTP1), mRNA [NM_024719] -1.5624361 0.0416334 NM_001029857 LOC158381 Homo sapiens hypothetical protein LOC158381 (LOC158381), mRNA [NM_001029857] Homo sapiens chromosome 20 open reading frame 43, mRNA (cDNA clone IMAGE:3615348), complete cds. -1.5631038 0.035151448 BC002769 C20orf43 [BC002769] -1.5643702 0.006602355 NM_005788 PRMT3 Homo sapiens protein arginine methyltransferase 3 (PRMT3), mRNA [NM_005788] -1.5648558 0.00147318 NM_139076 CCDC98 Homo sapiens coiled-coil domain containing 98 (CCDC98), mRNA [NM_139076] Homo sapiens eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (EIF2S1), mRNA -1.5656512 0.0437438 NM_004094 EIF2S1 [NM 004094] -1.5667201 0.018150445 A_24_P281730 Homo sapiens nuclear factor of activated T-cells, cytoplasmic, -dependent 2 interacting protein -1.5704558 0.029230177 NM_032815 NFATC2IP (NFATC2IP), mRNA [NM 032815] -1.5705808 0.04349269 NM_004329 BMPR1A Homo sapiens bone morphogenetic protein receptor, type IA (BMPR1A), mRNA [NM_004329] -1.5709087 0.045317214 NM_138286 ZNF681 Homo sapiens zinc finger protein 681 (ZNF681), mRNA [NM_138286] -1.5711497 0.02333882 NM_014703 VPRBP Homo sapiens Vpr (HIV-1) binding protein (VPRBP), mRNA [NM_014703] -1.5747046 0.030198433 NM_001012398 AKTIP Homo sapiens AKT interacting protein (AKTIP), transcript variant 1, mRNA [NM_001012398] Homo sapiens fibroblast growth factor (acidic) intracellular binding protein (FIBP), transcript variant 2, -1.5778623 0.010656417 NM_004214 FIBP mRNA [NM 004214] -1.5798945 0.029628862 LOC284288 PREDICTED: Homo sapiens similar to ribosomal protein L24-like (LOC284288), mRNA [XM_210365] -1.5814826 0.033580326 NM_032826 SLC35B4 Homo sapiens solute carrier family 35, member B4 (SLC35B4), mRNA [NM_032826] -1.5824887 0.036519036 NM_014016 SACM1L Homo sapiens SAC1 suppressor of actin 1-like (yeast) (SACM1L), mRNA [NM_014016] -1.5827705 0.009604078 THC2522342 Q80YT0_MOUSE (Q80YT0) Whdc1 protein, partial (4%) [THC2522342] -1.583778 0.013782506 NM_001009567 MRC1L1 Homo sapiens , C type 1-like 1 (MRC1L1), mRNA [NM_001009567] -1.5838302 0.003128064 NM_175859 CTPS2 Homo sapiens CTP synthase II (CTPS2), transcript variant 2, mRNA [NM_175859] -1.5868 0.04460832 THG1L interphase cytoplasmic foci protein 45 [Source:RefSeq_peptide;Acc:NP_060342] [ENST00000231198] -1.587721 0.016228482 NM_173471 SLC25A26 Homo sapiens solute carrier family 25, member 26 (SLC25A26), mRNA [NM_173471] -1.5883489 0.043013975 NM_005610 RBBP4 Homo sapiens retinoblastoma binding protein 4 (RBBP4), mRNA [NM_005610] -1.5888947 0.009501606 NM_152834 TMEM18 Homo sapiens transmembrane protein 18 (TMEM18), mRNA [NM_152834] -1.5893744 0.012226506 NM_005707 PDCD7 Homo sapiens programmed cell death 7 (PDCD7), mRNA [NM_005707] PREDICTED: Homo sapiens similar to (S-adenosyl-L-homocysteine hydrolase) -1.5899531 0.04156426 XR_018584 LOC129560 (AdoHcyase) (LOC129560), mRNA [XR 018584] -1.592622 0.02717509 NM_152485 Homo sapiens chromosome 1 open reading frame 74 (C1orf74), mRNA [NM_152485] AF220206 Nedd4 WW domain-binding protein 2 {Mus musculus} (exp=-1; wgp=0; cg=0), partial (52%) -1.5929017 0.016862962 THC2656784 [THC2656784] -1.594535 0.04156854 NM_005687 FARSB Homo sapiens phenylalanyl-tRNA synthetase, beta subunit (FARSB), mRNA [NM_005687] -1.5961592 0.049467392 NM_012068 ATF5 Homo sapiens activating transcription factor 5 (ATF5), mRNA [NM_012068] -1.6012273 0.011025931 A_32_P231743 -1.6059096 0.0402256 NM_005662 VDAC3 Homo sapiens voltage-dependent anion channel 3 (VDAC3), mRNA [NM_005662] -1.6082962 0.01722333 ENST00000379864 OTTHUMP00000018257. [Source:Uniprot/SPTREMBL;Acc:Q9H1T5] [ENST00000379864] -1.6104256 0.039075486 NM_002692 POLE2 Homo sapiens polymerase (DNA directed), epsilon 2 (p59 subunit) (POLE2), mRNA [NM_002692] -1.6128368 0.018172536 NM_030877 CTNNBL1 Homo sapiens catenin, beta like 1 (CTNNBL1), mRNA [NM_030877] Homo sapiens protein phosphatase 1, catalytic subunit, beta isoform (PPP1CB), transcript variant 1, mRNA -1.6136092 0.045473926 NM_002709 PPP1CB [NM 002709] Homo sapiens vacuolar protein sorting 13 homolog B (yeast) (VPS13B), transcript variant 1, mRNA -1.6138685 0.020556292 NM_152564 VPS13B [NM 152564] Homo sapiens Fanconi anemia, complementation group B (FANCB), transcript variant 2, mRNA -1.6142398 0.03597602 NM_152633 FANCB [NM 152633] -1.6179248 0.031856846 NM_018639 WSB2 Homo sapiens WD repeat and SOCS box-containing 2 (WSB2), mRNA [NM_018639] -1.618754 0.011565494 CR749720 PGS1 Homo sapiens mRNA; cDNA DKFZp762M186 (from clone DKFZp762M186). [CR749720] -1.6193272 0.048745498 A_24_P247493

-1.6195513 0.010309113 ENST00000321130 Uncharacterized protein KIAA0391. [Source:Uniprot/SWISSPROT;Acc:O15091] [ENST00000321130] Homo sapiens caspase 10, apoptosis-related cysteine peptidase (CASP10), transcript variant B, mRNA -1.6216812 0.022145621 NM_032974 CASP10 [NM 032974] -1.6238741 0.033698328 AL390143 AL390143 Homo sapiens mRNA; cDNA DKFZp547N074 (from clone DKFZp547N074) [AL390143] -1.6248177 0.002397543 NM_004623 TTC4 Homo sapiens tetratricopeptide repeat domain 4 (TTC4), mRNA [NM_004623] -1.6250583 0.02092769 NM_030953 TIGD6 Homo sapiens tigger transposable element derived 6 (TIGD6), mRNA [NM_030953] -1.6256896 0.0064171 CR749275 CTNND1 Homo sapiens mRNA; cDNA DKFZp781O2021 (from clone DKFZp781O2021). [CR749275] Homo sapiens ELKS/RAB6-interacting/CAST family member 1 (ERC1), transcript variant beta, mRNA -1.6290262 0.033791926 NM_178037 ERC1 [NM 178037] -1.6307602 0.011480772 NM_152363 ANKRD41 Homo sapiens ankyrin repeat domain 41 (ANKRD41), mRNA [NM_152363] -1.6316568 0.049604688 NM_000671 ADH5 Homo sapiens alcohol dehydrogenase 5 (class III), chi polypeptide (ADH5), mRNA [NM_000671] -1.6346222 0.008172403 NM_022344 C17orf75 Homo sapiens chromosome 17 open reading frame 75 (C17orf75), mRNA [NM_022344] Homo sapiens potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 -1.636272 0.035538442 NM_002248 KCNN1 (KCNN1), mRNA [NM 002248] -1.63711 0.02966257 ENST00000373268 Homo sapiens cDNA clone IMAGE:30416677. [BC090920] -1.6390934 0.027101284 AK025762 AK025762 Homo sapiens cDNA: FLJ22109 fis, clone HEP18091. [AK025762] -1.6397836 0.04538172 A_32_P19616 -1.641009 0.004164573 NM_177965 C8orf37 Homo sapiens chromosome 8 open reading frame 37 (C8orf37), mRNA [NM_177965] Homo sapiens mitochondrial ribosomal protein L45 (MRPL45), nuclear gene encoding mitochondrial protein, -1.6423182 0.019262552 NM_032351 MRPL45 mRNA [NM 032351] -1.6492984 0.030203676 NM_016519 AMBN Homo sapiens ameloblastin (enamel matrix protein) (AMBN), mRNA [NM_016519] -1.6498824 0.004535862 NM_145080 NSMCE1 Homo sapiens non-SMC element 1 homolog (S. cerevisiae) (NSMCE1), mRNA [NM_145080] -1.6524358 0.028737508 THC2778545 Q5IKF4_9VIRU (Q5IKF4) G20 (Fragment), partial (9%) [THC2778545] -1.6554344 0.039763637 NM_019054 FAM35A Homo sapiens family with sequence similarity 35, member A (FAM35A), mRNA [NM_019054] BE328135 ht97e11.x1 NCI_CGAP_Lu24 Homo sapiens cDNA clone IMAGE:3165068 3' similar to contains -1.6559948 0.014783951 BE328135 BE328135 Alu repetitive element;, mRNA sequence [BE328135] -1.6560329 0.016708469 NM_152456 C16orf77 Homo sapiens chromosome 16 open reading frame 77 (C16orf77), mRNA [NM_152456] -1.6577016 0.028340757 NM_003437 ZNF136 Homo sapiens zinc finger protein 136 (ZNF136), mRNA [NM_003437] -1.6577171 0.031409003 A_32_P104995 ym27h06.r1 Soares infant brain 1NIB Homo sapiens cDNA clone IMAGE:49510 5', mRNA sequence -1.6594481 0.03167645 H15635 H15635 [H15635] -1.6637568 0.01846329 NM_207306 KIAA0495 Homo sapiens KIAA0495 (KIAA0495), mRNA [NM_207306] Homo sapiens recombination signal binding protein for immunoglobulin kappa J region (RBPJ), transcript -1.6648353 0.023915114 NM_203284 RBPJ variant 4, mRNA [NM 203284] -1.6662369 0.048097026 NM_019023 PRMT7 Homo sapiens protein arginine methyltransferase 7 (PRMT7), mRNA [NM_019023] -1.6686631 0.022585617 THC2683295 -1.6728354 0.029190183 NM_018386 PCID2 Homo sapiens PCI domain containing 2 (PCID2), mRNA [NM_018386] -1.6733576 0.046229307 NM_024595 C1orf108 Homo sapiens chromosome 1 open reading frame 108 (C1orf108), mRNA [NM_024595] -1.6742529 0.045014802 NM_017707 DDEFL1 Homo sapiens development and differentiation enhancing factor-like 1 (DDEFL1), mRNA [NM_017707] -1.6747054 0.007499386 BC052945 LOC643201 Homo sapiens cDNA clone IMAGE:5268504. [BC052945] -1.6786926 0.016169379 NM_032590 FBXL10 Homo sapiens F-box and leucine-rich repeat protein 10 (FBXL10), transcript variant 1, mRNA [NM_032590] -1.6793067 0.00150831 NM_004805 POLR2D Homo sapiens polymerase (RNA) II (DNA directed) polypeptide D (POLR2D), mRNA [NM_004805] Homo sapiens ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 (ATP6V1B2), mRNA -1.6795783 0.03791223 NM_001693 ATP6V1B2 [NM 001693] Homo sapiens family with sequence similarity 63, member B (FAM63B), transcript variant 2, mRNA -1.6798743 0.0255454 NM_001040453 FAM63B [NM 001040453] -1.6817138 0.04253 A_24_P349489 -1.6817772 0.020794256 AK074886 LOC389634 Homo sapiens cDNA FLJ90405 fis, clone NT2RP2006099. [AK074886] -1.6825737 0.034797803 NM_002164 INDO Homo sapiens indoleamine-pyrrole 2,3 dioxygenase (INDO), mRNA [NM_002164] Homo sapiens phosphatidylinositol transfer protein, membrane-associated 2 (PITPNM2), mRNA -1.684798 0.00241133 NM_020845 PITPNM2 [NM 020845] PREDICTED: Homo sapiens similar to Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) -1.6856371 0.046714995 XR_019062 LOC643513 (RAG cohort protein 1) (LOC643513), mRNA [XR 019062] Homo sapiens OTU domain, ubiquitin aldehyde binding 1 (OTUB1), transcript variant 1, mRNA -1.6860313 0.03506339 NM_017670 OTUB1 [NM 017670] Homo sapiens CDC14 cell division cycle 14 homolog C (S. cerevisiae), mRNA (cDNA clone -1.6881909 0.011839622 BC028690 CDC14C IMAGE:4826219), partial cds. [BC028690] -1.6897364 0.026883807 NM_001012732 DCTD Homo sapiens dCMP deaminase (DCTD), transcript variant 1, mRNA [NM_001012732] -1.6907452 0.049757313 NM_030901 OR7A17 Homo sapiens olfactory receptor, family 7, subfamily A, member 17 (OR7A17), mRNA [NM_030901] -1.6924405 0.044688165 CR627362 LOC595101 Homo sapiens mRNA; cDNA DKFZp686H21113 (from clone DKFZp686H21113). [CR627362] -1.6949497 0.020152334 A_23_P255637 -1.6956879 0.011598694 AK096853 FLJ39534 Homo sapiens cDNA FLJ39534 fis, clone PUAEN2005247. [AK096853] Homo sapiens potassium voltage-gated channel, KQT-like subfamily, member 5 (KCNQ5), mRNA -1.6971015 0.023577832 NM_019842 KCNQ5 [NM 019842] -1.6971631 0.03193586 AK026403 AK026403 Homo sapiens cDNA: FLJ22750 fis, clone KAIA0478. [AK026403] -1.6977955 0.025477331 NM_004890 SPAG7 Homo sapiens sperm associated antigen 7 (SPAG7), mRNA [NM_004890] -1.7011409 0.036082614 NM_001753 CAV1 Homo sapiens caveolin 1, caveolae protein, 22kDa (CAV1), mRNA [NM_001753] Homo sapiens vacuolar protein sorting 13 homolog B (yeast) (VPS13B), transcript variant 3, mRNA -1.7024506 0.023857815 NM_015243 VPS13B [NM 015243] -1.7047724 0.025882766 NM_001040653 ZXDC Homo sapiens ZXD family zinc finger C (ZXDC), transcript variant 2, mRNA [NM_001040653] -1.7048291 0.009865501 NM_006366 CAP2 Homo sapiens CAP, adenylate cyclase-associated protein, 2 (yeast) (CAP2), mRNA [NM_006366] Homo sapiens similar to Cohesin subunit SA-3 (Stromal antigen 3) (Stromalin 3) (SCC3 homolog 3) -1.7066334 0.040722344 NM_001013739 LOC442578 (LOC442578), mRNA [NM 001013739] -1.7073671 0.047625523 XR_018868 LOC645000 PREDICTED: Homo sapiens similar to 40S ribosomal protein S3 (LOC645000), mRNA [XR_018868] -1.7092413 0.025895407 NM_004774 PPARBP Homo sapiens PPAR binding protein (PPARBP), mRNA [NM_004774] -1.7099304 0.01764742 NM_139048 HLTF Homo sapiens helicase-like transcription factor (HLTF), transcript variant 2, mRNA [NM_139048] -1.710525 0.04742335 NM_173531 ZNF100 Homo sapiens zinc finger protein 100 (ZNF100), mRNA [NM_173531] -1.712311 0.04879339 NM_024498 ZNF117 Homo sapiens zinc finger protein 117 (ZNF117), mRNA [NM_024498] -1.7133521 0.01984152 NM_001013631 HNRPCL1 Homo sapiens heterogeneous nuclear ribonucleoprotein C-like 1 (HNRPCL1), mRNA [NM_001013631] -1.7144969 0.044861704 NM_152263 TPM3 Homo sapiens tropomyosin 3 (TPM3), transcript variant 1, mRNA [NM_152263] Homo sapiens 3-phosphoinositide dependent protein kinase-1 (PDPK1), transcript variant 1, mRNA -1.7158316 0.00413181 NM_002613 PDPK1 [NM 002613] -1.7170105 0.005443085 NM_015465 GEMIN5 Homo sapiens gem (nuclear organelle) associated protein 5 (GEMIN5), mRNA [NM_015465] -1.7170566 0.036421325 NM_020240 CDC42SE2 Homo sapiens CDC42 small effector 2 (CDC42SE2), transcript variant 1, mRNA [NM_020240] -1.7198186 0.028198615 NM_018835 RC3H2 Homo sapiens ring finger and CCCH-type zinc finger domains 2 (RC3H2), mRNA [NM_018835] -1.7202492 0.040518172 NM_001001415 ZNF429 Homo sapiens zinc finger protein 429 (ZNF429), mRNA [NM_001001415] -1.724593 0.037178505 NM_153026 PRICKLE1 Homo sapiens prickle homolog 1 (Drosophila) (PRICKLE1), mRNA [NM_153026] -1.7246288 0.038817335 NM_144709 FLJ32312 Homo sapiens hypothetical protein FLJ32312 (FLJ32312), mRNA [NM_144709] -1.7255877 0.012395789 A_24_P101146

-1.7280506 0.006317831 NM_024081 PRRG4 Homo sapiens proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) (PRRG4), mRNA [NM_024081] -1.7310976 0.043375906 A_24_P93052 -1.7345606 0.032625347 NM_182527 CABP7 Homo sapiens calcium binding protein 7 (CABP7), mRNA [NM_182527] -1.7399038 0.04560169 THC2505770 -1.7410501 0.031764675 NM_024095 ASB8 Homo sapiens ankyrin repeat and SOCS box-containing 8 (ASB8), mRNA [NM_024095] -1.7417712 0.006404362 NM_032336 GINS4 Homo sapiens GINS complex subunit 4 (Sld5 homolog) (GINS4), mRNA [NM_032336] Homo sapiens gem (nuclear organelle) associated protein 8 (GEMIN8), transcript variant 3, mRNA -1.7435949 0.030445263 NM_017856 GEMIN8 [NM 017856] Homo sapiens cDNA FLJ34909 fis, clone NT2RI2009301, moderately similar to BIFUNCTIONAL -1.7439222 0.04261403 AK092228 LOC285216 METHYLENETETRAHYDROFOLATE DEHYDROGENASE/CYCLOHYDROLASE, MITOCHONDRIAL PRECURSOR. [AK092228] -1.7452435 0.028029382 ENST00000328281 -1.7457515 0.029250756 NM_006242 PPP1R3D Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 3D (PPP1R3D), mRNA [NM_006242] Homo sapiens La ribonucleoprotein domain family, member 4 (LARP4), transcript variant 2, mRNA -1.7492648 0.004025955 NM_199188 LARP4 [NM 199188] -1.7528446 0.047411405 S79672 S79672 Homo sapiens EWS/WT1 fusion protein (EWS1/WT1) mRNA, partial cds. [S79672] -1.7542259 0.040488012 AF323119 NFE2L2 Homo sapiens NF-E2-related factor 2 mRNA, partial cds. [AF323119] -1.7549686 0.012399697 A_24_P161655 -1.7582399 0.005905094 NM_015042 ZNF609 Homo sapiens zinc finger protein 609 (ZNF609), mRNA [NM_015042] -1.7588887 0.001534878 NM_014827 ZC3H11A Homo sapiens zinc finger CCCH-type containing 11A (ZC3H11A), mRNA [NM_014827] Homo sapiens actin related protein 2/3 complex, subunit 4, 20kDa (ARPC4), transcript variant 1, mRNA -1.7607574 0.039932247 NM_005718 ARPC4 [NM 005718] -1.7627386 0.003307086 NM_022877 SMN2 Homo sapiens survival of motor neuron 2, centromeric (SMN2), transcript variant c, mRNA [NM_022877] -1.7649817 0.019532641 NM_014611 MDN1 Homo sapiens MDN1, midasin homolog (yeast) (MDN1), mRNA [NM_014611] BF195775 7o79g05.x1 NCI_CGAP_Kid11 Homo sapiens cDNA clone IMAGE:3642800 3' similar to -1.7682084 1.25E-04 BF195775 BF195775 contains Alu repetitive element;, mRNA sequence [BF195775] -1.7697797 0.004904016 NM_207111 TRIAD3 Homo sapiens TRIAD3 protein (TRIAD3), transcript variant 1, mRNA [NM_207111] -1.7702174 0.024960542 NM_153838 GPR115 Homo sapiens G protein-coupled receptor 115 (GPR115), mRNA [NM_153838] -1.7710006 0.027591743 NR_001527 TTTY6 Homo sapiens testis-specific transcript, Y-linked 6 (TTTY6) on chromosome Y [NR_001527] -1.7785097 0.024123667 NM_003441 ZNF141 Homo sapiens zinc finger protein 141 (ZNF141), mRNA [NM_003441] -1.7790407 3.64E-04 A_24_P272503

-1.7792314 0.011961342 NM_206962 PRMT2 Homo sapiens protein arginine methyltransferase 2 (PRMT2), transcript variant 1, mRNA [NM_206962] -1.784762 0.038952433 XR_018955 LOC650775 PREDICTED: Homo sapiens similar to Protein FAM51A1 (LOC650775), mRNA [XR_018955] -1.7863693 0.049818434 NM_001364 DLG2 Homo sapiens discs, large homolog 2, chapsyn-110 (Drosophila) (DLG2), mRNA [NM_001364] Homo sapiens solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), -1.7865229 0.023930531 NM_004170 SLC1A1 member 1 (SLC1A1), mRNA [NM 004170] -1.7875919 0.013780611 NM_001010971 SAMD13 Homo sapiens sterile alpha motif domain containing 13 (SAMD13), mRNA [NM_001010971] -1.7929963 0.03365933 NM_024077 SECISBP2 Homo sapiens SECIS binding protein 2 (SECISBP2), mRNA [NM_024077] -1.7931391 0.02615482 NM_020235 BBX Homo sapiens bobby sox homolog (Drosophila) (BBX), mRNA [NM_020235] -1.7946622 0.01798192 NM_153649 TPM3 Homo sapiens tropomyosin 3 (TPM3), transcript variant 2, mRNA [NM_153649] -1.797625 0.00948885 ENST00000325122 RST26093 Athersys RAGE Library Homo sapiens cDNA, mRNA sequence [BG206642] -1.7996254 0.027782142 NM_153201 HSPA8 Homo sapiens heat shock 70kDa protein 8 (HSPA8), transcript variant 2, mRNA [NM_153201] -1.8018274 0.03781481 NM_182558 C12orf36 Homo sapiens chromosome 12 open reading frame 36 (C12orf36), mRNA [NM_182558] -1.8067527 0.012016949 A_23_P65845 -1.8109556 0.02813927 NM_006821 ACOT2 Homo sapiens acyl-CoA thioesterase 2 (ACOT2), mRNA [NM_006821] -1.8133875 0.03436973 NM_024533 CHST5 Homo sapiens carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 (CHST5), mRNA [NM_024533] Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa (NDUFA10), nuclear -1.8134382 0.014672207 NM_004544 NDUFA10 gene encoding mitochondrial protein, mRNA [NM 004544] -1.8134992 0.021316383 NM_002913 RFC1 Homo sapiens replication factor C (activator 1) 1, 145kDa (RFC1), mRNA [NM_002913] -1.8144364 0.015539067 NM_014974 DIP2C Homo sapiens DIP2 disco-interacting protein 2 homolog C (Drosophila) (DIP2C), mRNA [NM_014974] -1.815381 0.023916826 NM_001624 AIM1 Homo sapiens absent in melanoma 1 (AIM1), mRNA [NM_001624] Homo sapiens kelch repeat and BTB (POZ) domain containing 4 (KBTBD4), transcript variant 2, mRNA -1.8162205 0.04040063 NM_016506 KBTBD4 [NM 016506] -1.817708 0.022573885 BC045718 BC045718 Homo sapiens cDNA clone IMAGE:4797078. [BC045718] -1.8186417 0.022555323 A_24_P452175 -1.8234818 0.012638682 NM_020857 VPS18 Homo sapiens vacuolar protein sorting 18 homolog (S. cerevisiae) (VPS18), mRNA [NM_020857] -1.8235552 0.041218176 AB040944 ZSWIM5 Homo sapiens mRNA for KIAA1511 protein, partial cds. [AB040944] -1.8241591 0.040440146 NM_014106 ZNF770 Homo sapiens zinc finger protein 770 (ZNF770), mRNA [NM_014106] -1.8321902 0.030219983 NM_145273 CD300LG Homo sapiens CD300 molecule-like family member g (CD300LG), mRNA [NM_145273] -1.8365473 0.032146435 NM_000532 PCCB Homo sapiens propionyl Coenzyme A carboxylase, beta polypeptide (PCCB), mRNA [NM_000532] Homo sapiens TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa -1.8374109 0.020519601 NM_004606 TAF1 (TAF1), transcript variant 1, mRNA [NM 004606] Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 8 (PPP1R8), transcript variant 2, mRNA -1.8397287 0.038843367 NM_138558 PPP1R8 [NM 138558] Homo sapiens golgi associated, gamma adaptin ear containing, ARF binding protein 2 (GGA2), mRNA -1.8434706 0.04549377 NM_015044 GGA2 [NM 015044] -1.8473408 0.046389636 NM_032217 ANKRD17 Homo sapiens ankyrin repeat domain 17 (ANKRD17), transcript variant 1, mRNA [NM_032217] -1.8482164 0.012007287 AK125269 AK125269 Homo sapiens cDNA FLJ43279 fis, clone KIDNE2018217. [AK125269] -1.8507427 0.014477421 NM_199282 ARHGAP27 Homo sapiens Rho GTPase activating protein 27 (ARHGAP27), mRNA [NM_199282] -1.8565418 0.021216739 BC022830 LOC642852 Homo sapiens hypothetical LOC642852, mRNA (cDNA clone IMAGE:4581955), partial cds. [BC022830] -1.8623347 0.03498188 NM_022756 C1orf149 Homo sapiens chromosome 1 open reading frame 149 (C1orf149), mRNA [NM_022756] -1.8670528 0.030524539 NM_005885 6-Mar Homo sapiens membrane-associated ring finger (C3HC4) 6 (MARCH6), mRNA [NM_005885] -1.8677258 0.002430265 LOC645332 Homo sapiens cDNA FLJ31209 fis, clone KIDNE2003377. [AK055771] AW076051 xa83g01.x1 NCI_CGAP_CML1 Homo sapiens cDNA clone IMAGE:2573424 3' similar to -1.8729241 0.03424541 AW076051 AW076051 TR:O75594 O75594 PEPTIDOGLYCAN RECOGNITION PROTEIN PRECURSOR. ;, mRNA sequence [AW076051] -1.8774128 0.017617349 AK074291 AK074291 Homo sapiens cDNA FLJ23711 fis, clone HEP12371. [AK074291] -1.8784732 0.02908634 A_32_P130217 -1.889496 0.01399215 NM_001080477 ODZ3 Homo sapiens odz, odd Oz/ten-m homolog 3 (Drosophila) (ODZ3), mRNA [NM_001080477] -1.8957427 0.041316792 THC2719959 -1.8966208 0.029916756 THC2757796 BE007076 PM3-BN0137-290300-002-g09 BN0137 Homo sapiens cDNA, mRNA sequence [BE007076] -1.89951 0.012189012 A_24_P152278 -1.8995775 0.005487765 NM_013264 DDX25 Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 (DDX25), mRNA [NM_013264] -1.9014866 0.04259585 NR_001446 ANXA2P3 Homo sapiens annexin A2 pseudogene 3 (ANXA2P3) on chromosome 10 [NR_001446] -1.9028548 0.018246941 CV575560 CV575560 oe37f10.y1 Human keratoconus cornea, unamplified, (od [CV575560] -1.9046576 0.033406917 NM_025040 ZNF614 Homo sapiens zinc finger protein 614 (ZNF614), mRNA [NM_025040] PEBP_MOUSE (P70296) Phosphatidylethanolamine-binding protein (PEBP) (HCNPpp) [Contains: -1.9092007 0.046986096 THC2651548 Hippocampal cholinergic neurostimulating peptide (HCNP)], complete [THC2651548] -1.9125047 0.002111734 XM_373495 LOC387761 PREDICTED: Homo sapiens hypothetical LOC387761 (LOC387761), mRNA [XM_373495] -1.9138322 0.023013111 NM_153649 TPM3 Homo sapiens tropomyosin 3 (TPM3), transcript variant 2, mRNA [NM_153649] -1.9144037 0.030944003 NM_003850 SUCLA2 Homo sapiens succinate-CoA ligase, ADP-forming, beta subunit (SUCLA2), mRNA [NM_003850] -1.9150336 0.04876661 NM_022101 CXorf56 Homo sapiens chromosome X open reading frame 56 (CXorf56), mRNA [NM_022101] -1.921888 0.023393976 AK054879 AK054879 Homo sapiens cDNA FLJ30317 fis, clone BRACE2003594. [AK054879] -1.9249296 0.03141865 NM_006275 SFRS6 Homo sapiens splicing factor, arginine/serine-rich 6 (SFRS6), mRNA [NM_006275] -1.9269783 0.02646993 NM_032195 SON Homo sapiens SON DNA binding protein (SON), transcript variant b, mRNA [NM_032195] Homo sapiens sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E -1.9284384 0.041756507 NM_012431 SEMA3E (SEMA3E), mRNA [NM 012431] -1.9300847 0.021077441 ENST00000372871 Ribosomal protein L7-like 1. [Source:Uniprot/SWISSPROT;Acc:Q6DKI1] [ENST00000372871] -1.9359459 6.02E-04 NM_030918 SNX27 Homo sapiens sorting nexin family member 27 (SNX27), mRNA [NM_030918] -1.9377239 0.035018735 NM_002759 EIF2AK2 Homo sapiens eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2), mRNA [NM_002759] -1.9377456 0.007694596 NM_001610 ACP2 Homo sapiens acid phosphatase 2, lysosomal (ACP2), mRNA [NM_001610] -1.9541095 0.015295057 A_32_P58705 -1.9574676 0.04229631 NM_001402 EEF1A1 Homo sapiens eukaryotic translation elongation factor 1 alpha 1 (EEF1A1), mRNA [NM_001402] -1.9618212 0.045534555 NM_002785 PSG11 Homo sapiens pregnancy specific beta-1-glycoprotein 11 (PSG11), transcript variant 1, mRNA [NM_002785] Homo sapiens cDNA FLJ38288 fis, clone FCBBF3008382, weakly similar to Homo sapiens C2H2 (Kruppel- -1.965561 0.037105933 AK095607 ZNF776 type) zinc finger protein mRNA. [AK095607] Homo sapiens required for Sp1 transcriptional activation, subunit 8, 34kDa (CRSP8), mRNA -1.9682729 0.028221436 NM_004269 CRSP8 [NM 004269] -1.9718463 0.04173997 NM_016004 IFT52 Homo sapiens intraflagellar transport 52 homolog (Chlamydomonas) (IFT52), mRNA [NM_016004] -1.9781212 0.013904903 NM_012388 PLDN Homo sapiens pallidin homolog (mouse) (PLDN), mRNA [NM_012388] -1.9800344 0.03421414 NM_053024 PFN2 Homo sapiens profilin 2 (PFN2), transcript variant 1, mRNA [NM_053024] -1.9827371 0.038453765 NM_000868 HTR2C Homo sapiens 5-hydroxytryptamine (serotonin) receptor 2C (HTR2C), mRNA [NM_000868] -1.9836854 0.029805806 NM_018107 RBM23 Homo sapiens RNA binding motif protein 23 (RBM23), transcript variant 2, mRNA [NM_018107] membrane-associated guanylate kinase-related 3 isoform 1 [Source:RefSeq_peptide;Acc:NP_066016] -1.9873083 0.049237322 MAGI3 [ENST00000369615] -1.9874429 0.03731752 BC043212 LOC402125 Homo sapiens cDNA clone IMAGE:5295205, with apparent retained intron. [BC043212] -1.9875185 0.02571744 NM_177438 DICER1 Homo sapiens Dicer1, Dcr-1 homolog (Drosophila) (DICER1), transcript variant 1, mRNA [NM_177438] -1.9905448 0.030572312 XR_015785 LOC402643 PREDICTED: Homo sapiens tropomyosin 3-like (LOC402643), misc RNA [XR_015785] -2.000454 0.0490006 NM_004614 TK2 Homo sapiens thymidine kinase 2, mitochondrial (TK2), mRNA [NM_004614] Homo sapiens ribosomal protein L23, mRNA (cDNA clone MGC:34067 IMAGE:5186030), complete cds. -2.0013158 0.038948666 BC034378 RPL23 [BC034378] -2.0072846 0.04258409 THC2603461 Q8INN3_DROME (Q8INN3) CG31415-PA (IP07196p), partial (8%) [THC2603461] -2.0076838 0.04471139 NM_198486 RPL7L1 Homo sapiens ribosomal protein L7-like 1 (RPL7L1), mRNA [NM_198486] Homo sapiens myeloid/lymphoid or mixed-lineage leukemia 3 (MLL3), transcript variant 2, mRNA -2.0096896 0.041270178 NM_170606 MLL3 [NM 170606] -2.0155127 0.039954275 NM_138790 PLD4 Homo sapiens family, member 4 (PLD4), mRNA [NM_138790] -2.0185418 0.002024276 NM_003940 USP13 Homo sapiens ubiquitin specific peptidase 13 (isopeptidase T-3) (USP13), mRNA [NM_003940] -2.0198822 0.007716059 NM_003707 RUVBL1 Homo sapiens RuvB-like 1 (E. coli) (RUVBL1), mRNA [NM_003707] -2.0217772 0.048731487 NM_080662 PEX11G Homo sapiens peroxisomal biogenesis factor 11 gamma (PEX11G), mRNA [NM_080662] Homo sapiens tumor necrosis factor (ligand) superfamily, member 11 (TNFSF11), transcript variant 1, mRNA -2.0231597 0.030536836 NM_003701 TNFSF11 [NM 003701] -2.031132 0.014606348 X66610 ENO1B H.sapiens mRNA for enolase. [X66610] -2.0315845 0.047792297 NM_006572 GNA13 Homo sapiens guanine nucleotide binding protein (G protein), alpha 13 (GNA13), mRNA [NM_006572] -2.0413773 0.010960096 NM_001005234 OR1L3 Homo sapiens olfactory receptor, family 1, subfamily L, member 3 (OR1L3), mRNA [NM_001005234] -2.0415936 0.0410319 AK022865 FLJ22536 Homo sapiens cDNA FLJ12803 fis, clone NT2RP2002172. [AK022865] -2.0436163 0.014452095 NM_032933 C18orf45 Homo sapiens chromosome 18 open reading frame 45 (C18orf45), mRNA [NM_032933] -2.0451355 7.86E-04 NM_021224 ZNF462 Homo sapiens zinc finger protein 462 (ZNF462), mRNA [NM_021224] -2.0625243 0.00408658 NM_198941 SERINC3 Homo sapiens serine incorporator 3 (SERINC3), transcript variant 2, mRNA [NM_198941] -2.0663934 0.041550063 NM_000532 PCCB Homo sapiens propionyl Coenzyme A carboxylase, beta polypeptide (PCCB), mRNA [NM_000532] -2.0664654 0.044346347 THC2591726 -2.0681815 0.036679037 A_23_P118135 -2.070262 0.01948095 NM_014961 RUFY3 Homo sapiens RUN and FYVE domain containing 3 (RUFY3), transcript variant 2, mRNA [NM_014961] Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa (NDUFA10), nuclear -2.0721924 0.027609784 NM_004544 NDUFA10 gene encoding mitochondrial protein, mRNA [NM 004544] -2.0764966 0.011993895 NM_004498 ONECUT1 Homo sapiens one cut domain, family member 1 (ONECUT1), mRNA [NM_004498] -2.095433 0.023570344 XR_018350 LOC390618 PREDICTED: Homo sapiens similar to ribosomal protein L7-like 1 (LOC390618), mRNA [XR_018350] -2.1071074 0.04934722 NM_022574 PERQ1 Homo sapiens PERQ amino acid rich, with GYF domain 1 (PERQ1), mRNA [NM_022574] -2.1097898 0.01545391 NM_013293 TRA2A Homo sapiens transformer-2 alpha (TRA2A), mRNA [NM_013293] -2.1174362 0.009237955 NM_009589 ARSD Homo sapiens D (ARSD), transcript variant 2, mRNA [NM_009589] -2.119043 0.027749477 NM_020343 C20orf74 Homo sapiens chromosome 20 open reading frame 74 (C20orf74), mRNA [NM_020343] -2.1278834 0.017783344 NM_001690 ATP6V1A Homo sapiens ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A (ATP6V1A), mRNA [NM_001690] -2.1316566 0.04958542 A_24_P341489 -2.13531 0.023851888 AK094893 LOC645431 Homo sapiens cDNA FLJ37574 fis, clone BRCOC2003100. [AK094893] -2.1356883 0.012387008 NM_002463 MX2 Homo sapiens myxovirus (influenza virus) resistance 2 (mouse) (MX2), mRNA [NM_002463] -2.13751 0.043888457 NM_016004 IFT52 Homo sapiens intraflagellar transport 52 homolog (Chlamydomonas) (IFT52), mRNA [NM_016004] -2.1420825 0.04245063 NM_024771 NAT11 Homo sapiens N-acetyltransferase 11 (NAT11), mRNA [NM_024771] -2.1432307 0.040009484 A_24_P714620 -2.155862 0.047736574 NM_015576 ERC2 Homo sapiens ELKS/RAB6-interacting/CAST family member 2 (ERC2), mRNA [NM_015576] -2.155881 0.025896545 XR_018238 LOC347509 PREDICTED: Homo sapiens similar to ribosomal protein L7-like 1 (LOC347509), mRNA [XR_018238] -2.158825 0.04310792 NM_001080412 ZBTB38 Homo sapiens zinc finger and BTB domain containing 38 (ZBTB38), mRNA [NM_001080412] -2.159014 0.035281476 A_24_P75408 -2.161091 0.025833458 NM_152335 C15orf27 Homo sapiens chromosome 15 open reading frame 27 (C15orf27), mRNA [NM_152335] -2.1626008 0.044767044 NM_015359 SLC39A14 Homo sapiens solute carrier family 39 (zinc transporter), member 14 (SLC39A14), mRNA [NM_015359] Homo sapiens ATPase, aminophospholipid transporter (APLT), Class I, type 8A, member 1 (ATP8A1), -2.1682613 0.001506059 NM_006095 ATP8A1 mRNA [NM 006095] -2.1707742 0.01574047 NM_139280 ORMDL3 Homo sapiens ORM1-like 3 (S. cerevisiae) (ORMDL3), mRNA [NM_139280] Homo sapiens gamma-aminobutyric acid (GABA) A receptor, beta 3 (GABRB3), transcript variant 1, mRNA -2.171393 0.025248095 NM_000814 GABRB3 [NM 000814] -2.178071 0.02583808 NM_024750 LRRC2 Homo sapiens leucine rich repeat containing 2 (LRRC2), mRNA [NM_024750] Homo sapiens immunoglobulin kappa variable 1-5, mRNA (cDNA clone MGC:32715 IMAGE:4694346), -2.1823194 0.030852804 BC034142 IGKV1-5 complete cds. [BC034142] -2.1861165 0.001077005 BX648355 GSTCD Homo sapiens mRNA; cDNA DKFZp686I10174 (from clone DKFZp686I10174). [BX648355] -2.1904886 0.036571156 NM_018843 SLC25A40 Homo sapiens solute carrier family 25, member 40 (SLC25A40), mRNA [NM_018843] -2.1940846 0.004715822 NM_014613 UBXD8 Homo sapiens UBX domain containing 8 (UBXD8), mRNA [NM_014613] -2.1953907 0.022213908 NM_198486 RPL7L1 Homo sapiens ribosomal protein L7-like 1 (RPL7L1), mRNA [NM_198486] -2.2020483 0.010942964 NM_017650 PPP1R9A Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 9A (PPP1R9A), mRNA [NM_017650] -2.20706 0.015507853 CR627362 LOC595101 Homo sapiens mRNA; cDNA DKFZp686H21113 (from clone DKFZp686H21113). [CR627362] -2.2071927 0.008016367 AK091744 AK091744 Homo sapiens cDNA FLJ34425 fis, clone HHDPC2008297. [AK091744] Homo sapiens hCG2040556, mRNA (cDNA clone MGC:87053 IMAGE:5297972), complete cds. -2.2109985 0.014086349 BC068459 hCG_2040556 [BC068459] AL547890 AL547890 Homo sapiens PLACENTA COT 25-NORMALIZED Homo sapiens cDNA clone -2.2123682 0.008560865 AL547890 AL547890 CS0DI033YB09 5-PRIME, mRNA sequence [AL547890] -2.2150111 0.03996066 NM_173582 PGM2L1 Homo sapiens phosphoglucomutase 2-like 1 (PGM2L1), mRNA [NM_173582] -2.2168787 0.021983758 NM_014251 SLC25A13 Homo sapiens solute carrier family 25, member 13 (citrin) (SLC25A13), mRNA [NM_014251] PREDICTED: Homo sapiens similar to Heterogeneous nuclear ribonucleoprotein H (hnRNP H) -2.2180789 0.048970357 XR_018905 LOC402216 (LOC402216), mRNA [XR 018905] -2.2229278 0.0082421 XR_018167 LOC647690 PREDICTED: Homo sapiens similar to tubulin, alpha 1 (LOC647690), mRNA [XR_018167] -2.231287 0.03843872 NM_001012288 CRLF2 Homo sapiens cytokine receptor-like factor 2 (CRLF2), transcript variant 2, mRNA [NM_001012288] -2.233614 0.029632917 NM_024068 OBFC2B Homo sapiens oligonucleotide/oligosaccharide-binding fold containing 2B (OBFC2B), mRNA [NM_024068] -2.2351694 0.019133143 AK023769 ZNF552 Homo sapiens cDNA FLJ13707 fis, clone PLACE2000347. [AK023769] -2.2397838 0.041061457 NM_006089 SCML2 Homo sapiens sex comb on midleg-like 2 (Drosophila) (SCML2), mRNA [NM_006089] Homo sapiens Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1), transcript variant short, mRNA -2.2422905 0.04407896 NM_017778 WHSC1L1 [NM 017778] -2.243985 0.014169305 NM_207111 TRIAD3 Homo sapiens TRIAD3 protein (TRIAD3), transcript variant 1, mRNA [NM_207111] -2.2627337 0.010482132 XR_018701 LOC442161 PREDICTED: Homo sapiens similar to ribosomal protein L7-like 1 (LOC442161), mRNA [XR_018701] -2.2756796 0.029274156 FAM60A Protein FAM60A (Tera protein homolog). [Source:Uniprot/SWISSPROT;Acc:Q9NP50] [ENST00000337682] -2.2787893 0.049991436 NM_012388 PLDN Homo sapiens pallidin homolog (mouse) (PLDN), mRNA [NM_012388] -2.2807295 0.019067356 NM_004397 DDX6 Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 (DDX6), mRNA [NM_004397] Homo sapiens collagen, type IV, alpha 3 (Goodpasture antigen) binding protein (COL4A3BP), transcript -2.2887223 0.007135159 NM_005713 COL4A3BP variant 1, mRNA [NM 005713] -2.2957182 0.031063627 ZNF488 Zinc finger protein 488. [Source:Uniprot/SWISSPROT;Acc:Q96MN9] [ENST00000298129] -2.2957873 0.025723398 AK056260 AK056260 Homo sapiens cDNA FLJ31698 fis, clone NT2RI2005966. [AK056260] -2.2961867 0.049823362 NM_022353 OSGEPL1 Homo sapiens O-sialoglycoprotein endopeptidase-like 1 (OSGEPL1), mRNA [NM_022353] -2.3000958 0.037163768 NM_032753 RAXL1 Homo sapiens retina and anterior neural fold homeobox like 1 (RAXL1), mRNA [NM_032753] -2.3010092 0.022809329 NM_144600 C16orf63 Homo sapiens chromosome 16 open reading frame 63 (C16orf63), mRNA [NM_144600] -2.3085432 0.032168306 NM_005121 THRAP1 Homo sapiens thyroid associated protein 1 (THRAP1), mRNA [NM_005121] Pre-B-cell leukemia transcription factor 1 (Homeobox protein PBX1) (Homeobox protein PRL). -2.3129125 0.006598166 PBX1 [Source:Uniprot/SWISSPROT;Acc:P40424] [ENST00000328681] -2.3132765 0.038289756 NM_022569 NDST4 Homo sapiens N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 (NDST4), mRNA [NM_022569] -2.3145826 0.046890937 NM_001259 CDK6 Homo sapiens cyclin-dependent kinase 6 (CDK6), mRNA [NM_001259] -2.3161712 0.013560788 NM_194286 KIAA1853 Homo sapiens KIAA1853 (KIAA1853), mRNA [NM_194286] -2.3215163 0.045727916 NM_006591 POLD3 Homo sapiens polymerase (DNA-directed), delta 3, accessory subunit (POLD3), mRNA [NM_006591] -2.3222806 0.023938295 NM_018263 ASXL2 Homo sapiens additional sex combs like 2 (Drosophila) (ASXL2), mRNA [NM_018263] -2.3292902 0.019090753 A_24_P24806 -2.3317578 0.03231092 A_32_P136477 -2.335429 0.022850707 A_24_P464798 -2.3383234 0.038845208 AB209304 PAPOLG Homo sapiens mRNA for poly(A) polymerase gamma variant protein. [AB209304] PREDICTED: Homo sapiens similar to eukaryotic translation elongation factor 1 alpha 2 (LOC401717), -2.3467188 0.036379814 XR_018189 LOC401717 mRNA [XR 018189] Homo sapiens eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa (EIF2S3), mRNA -2.3480725 0.002342179 NM_001415 EIF2S3 [NM 001415] -2.3509314 0.017220736 A_23_P89680 Homo sapiens cell division cycle 25 homolog A (S. pombe) (CDC25A), transcript variant 1, mRNA -2.3553152 0.0352011 NM_001789 CDC25A [NM 001789] Homo sapiens ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) (CLN8), -2.3576195 0.02278123 NM_018941 CLN8 mRNA [NM 018941] Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 (PSMD11), mRNA -2.3587732 0.008883572 NM_002815 PSMD11 [NM 002815] -2.359639 0.035309207 AJ488204 NAV2 Homo sapiens partial mRNA for steerin2 protein (STEERIN2 gene), alternative exon 1c. [AJ488204] -2.364682 0.028656129 AL834350 PPP2R5C Homo sapiens mRNA; cDNA DKFZp761H0317 (from clone DKFZp761H0317). [AL834350] -2.3655171 0.042228676 THC2652887 Q2PGH6_HAELO (Q2PGH6) Mucin (Fragment), partial (14%) [THC2652887] -2.3691962 0.04389474 A_24_P324644 Homo sapiens runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (RUNX1T1), transcript -2.3699813 0.03209974 NM_004349 RUNX1T1 variant 1, mRNA [NM 004349] -2.3724947 0.02256684 NM_024758 AGMAT Homo sapiens agmatine () (AGMAT), mRNA [NM_024758] Homo sapiens sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -2.372659 0.001759595 NM_006080 SEMA3A (SEMA3A), mRNA [NM 006080] -2.3791294 0.044855036 A_23_P370408 -2.3811343 0.01560324 A_23_P71635 -2.3935347 0.04242399 NM_003557 PIP5K1A Homo sapiens phosphatidylinositol-4-phosphate 5-kinase, type I, alpha (PIP5K1A), mRNA [NM_003557] -2.3959904 0.016207846 NM_032147 USP44 Homo sapiens ubiquitin specific peptidase 44 (USP44), transcript variant 1, mRNA [NM_032147] -2.3970034 0.033463754 A_24_P41890 -2.3997846 0.030521084 NM_001402 EEF1A1 Homo sapiens eukaryotic translation elongation factor 1 alpha 1 (EEF1A1), mRNA [NM_001402] -2.4213152 0.013149552 NM_003439 ZKSCAN1 Homo sapiens zinc finger with KRAB and SCAN domains 1 (ZKSCAN1), mRNA [NM_003439] -2.4245899 0.04280925 NM_015071 ARHGAP26 Homo sapiens Rho GTPase activating protein 26 (ARHGAP26), mRNA [NM_015071] -2.4327633 0.047742374 NM_152279 ZNF585B Homo sapiens zinc finger protein 585B (ZNF585B), mRNA [NM_152279] -2.4334433 0.04368116 NM_002519 NPAT Homo sapiens nuclear protein, ataxia-telangiectasia (NPAT), mRNA [NM_002519] -2.4442625 0.009883214 NM_152263 TPM3 Homo sapiens tropomyosin 3 (TPM3), transcript variant 1, mRNA [NM_152263] -2.447861 0.034176968 NM_145641 APOL3 Homo sapiens apolipoprotein L, 3 (APOL3), transcript variant beta/a, mRNA [NM_145641] -2.450209 0.046127148 NM_013986 EWSR1 Homo sapiens Ewing sarcoma breakpoint region 1 (EWSR1), transcript variant EWS-b, mRNA [NM_013986]

-2.4665809 0.001481925 NM_181783 TMTC3 Homo sapiens transmembrane and tetratricopeptide repeat containing 3 (TMTC3), mRNA [NM_181783] -2.4686632 0.007918533 NM_000876 IGF2R Homo sapiens insulin-like growth factor 2 receptor (IGF2R), mRNA [NM_000876] -2.4720712 0.043659125 A_24_P474188 -2.5052125 0.02294538 NM_145652 WFDC5 Homo sapiens WAP four-disulfide core domain 5 (WFDC5), mRNA [NM_145652] -2.5057797 0.036220487 NM_018993 RIN2 Homo sapiens Ras and Rab interactor 2 (RIN2), mRNA [NM_018993] -2.5459433 0.030598557 NM_005561 LAMP1 Homo sapiens lysosomal-associated membrane protein 1 (LAMP1), mRNA [NM_005561] Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 (DDX31), transcript variant 2, mRNA -2.5893946 0.017600948 NM_138620 DDX31 [NM 138620] -2.593 0.02813747 NM_001010877 ZNF311 Homo sapiens zinc finger protein 311 (ZNF311), mRNA [NM_001010877] -2.6061168 0.015890414 NM_020682 AS3MT Homo sapiens arsenic (+3 oxidation state) methyltransferase (AS3MT), mRNA [NM_020682] -2.6462722 0.04266894 NM_152588 TMTC2 Homo sapiens transmembrane and tetratricopeptide repeat containing 2 (TMTC2), mRNA [NM_152588] -2.6753926 0.048987236 BC131554 BC131554 Homo sapiens cDNA clone IMAGE:40108029. [BC131554] -2.6842234 0.02674871 NM_006391 IPO7 Homo sapiens importin 7 (IPO7), mRNA [NM_006391] PREDICTED: Homo sapiens similar to Nucleosome assembly protein 1-like 4 (Nucleosome assembly protein -2.7069209 0.033478748 XR_015863 LOC731333 2) (NAP2) (LOC731333), mRNA [XR 015863] -2.7149048 0.038295507 NM_018229 C14orf108 Homo sapiens chromosome 14 open reading frame 108 (C14orf108), mRNA [NM_018229] -2.756076 0.015661826 NM_015092 SMG1 Homo sapiens PI-3-kinase-related kinase SMG-1 (SMG1), mRNA [NM_015092] Homo sapiens cDNA FLJ12427 fis, clone MAMMA1003127, highly similar to MYOSIN I ALPHA. -2.7772815 0.043536372 AK022489 MYO1B [AK022489] -2.7875688 0.021934962 NM_024611 NARG2 Homo sapiens NMDA receptor regulated 2 (NARG2), transcript variant 1, mRNA [NM_024611] Homo sapiens PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae) (PRPF19), mRNA -2.795982 0.011636287 NM_014502 PRPF19 [NM 014502] -2.7979627 0.009035934 NM_144711 KLHL23 Homo sapiens kelch-like 23 (Drosophila) (KLHL23), mRNA [NM_144711] -2.8002212 0.030444412 NM_017771 PXK Homo sapiens PX domain containing serine/threonine kinase (PXK), mRNA [NM_017771] -2.8029866 0.046417017 NM_133458 ZFP90 Homo sapiens zinc finger protein 90 homolog (mouse) (ZFP90), mRNA [NM_133458] -2.8343763 0.024764882 NM_175866 UHMK1 Homo sapiens U2AF homology motif (UHM) kinase 1 (UHMK1), mRNA [NM_175866] -2.8455281 0.014452288 NM_001957 EDNRA Homo sapiens endothelin receptor type A (EDNRA), mRNA [NM_001957] -2.8487318 0.048736576 AK124788 GGTL3 Homo sapiens cDNA FLJ42798 fis, clone BRAWH3008931. [AK124788] -2.8714762 0.03794408 NM_003358 UGCG Homo sapiens UDP-glucose ceramide (UGCG), mRNA [NM_003358] Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein. -2.899244 0.004434297 ENST00000295849 [Source:Uniprot/SWISSPROT;Acc:Q6ZP36] [ENST00000295849] -2.9596636 0.021029929 NM_053024 PFN2 Homo sapiens profilin 2 (PFN2), transcript variant 1, mRNA [NM_053024] Homo sapiens transient receptor potential cation channel, subfamily M, member 7 (TRPM7), mRNA -2.9914153 0.045877848 NM_017672 TRPM7 [NM 017672] -3.0126898 0.012610935 NM_006965 ZNF24 Homo sapiens zinc finger protein 24 (ZNF24), mRNA [NM_006965] -3.0154443 0.026858762 NM_004799 ZFYVE9 Homo sapiens zinc finger, FYVE domain containing 9 (ZFYVE9), transcript variant 3, mRNA [NM_004799] -3.0170257 0.014193103 NM_144711 KLHL23 Homo sapiens kelch-like 23 (Drosophila) (KLHL23), mRNA [NM_144711] -3.0906172 0.036977176 NM_002874 RAD23B Homo sapiens RAD23 homolog B (S. cerevisiae) (RAD23B), mRNA [NM_002874] -3.095604 0.03602414 AL359055 AL359055 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 2344436. [AL359055] -3.1076398 0.044294044 NM_016220 ZNF588 Homo sapiens zinc finger protein 588 (ZNF588), transcript variant 1, mRNA [NM_016220] -3.1504934 0.029141169 NM_017831 RNF125 Homo sapiens ring finger protein 125 (RNF125), mRNA [NM_017831] -3.1924882 0.006579669 A_24_P933372 -3.2247744 0.019770423 NM_007371 BRD3 Homo sapiens bromodomain containing 3 (BRD3), mRNA [NM_007371] -3.242359 0.038462345 AB011154 CEP68 Homo sapiens mRNA for KIAA0582 protein, partial cds. [AB011154] -3.301803 0.021369725 NM_198268 HIPK1 Homo sapiens homeodomain interacting protein kinase 1 (HIPK1), transcript variant 1, mRNA [NM_198268] BX119852 Soares_testis_NHT Homo sapiens cDNA clone IMAGp998I221826 ; IMAGE:743517, mRNA -3.315303 0.004883801 BX119852 BX119852 sequence [BX119852] -3.3324971 0.00807513 AB019490 RABGAP1L Homo sapiens IDN4-GGTR7 mRNA, partial cds. [AB019490] -3.3398032 0.022034476 AK022268 AK022268 Homo sapiens cDNA FLJ12206 fis, clone MAMMA1000941. [AK022268] -3.4225707 0.008768105 NM_015065 EXPH5 Homo sapiens exophilin 5 (EXPH5), mRNA [NM_015065] -3.4593773 0.031099001 NM_014744 TBC1D5 Homo sapiens TBC1 domain family, member 5 (TBC1D5), mRNA [NM_014744] -3.5067167 0.011468343 NM_006965 ZNF24 Homo sapiens zinc finger protein 24 (ZNF24), mRNA [NM_006965] -3.5146036 0.002065294 NM_138492 PRELID2 Homo sapiens PRELI domain containing 2 (PRELID2), transcript variant 3, mRNA [NM_138492] -3.6035225 0.037685536 AL833334 LOC283278 Homo sapiens mRNA; cDNA DKFZp686B1134 (from clone DKFZp686B1134). [AL833334] -3.6599538 0.036429994 NM_182515 ZNF714 Homo sapiens zinc finger protein 714 (ZNF714), mRNA [NM_182515] Homo sapiens cDNA FLJ42911 fis, clone BRHIP3024118, weakly similar to Monocarboxylate transporter 4. -3.7189791 0.03655309 AK124901 SLC16A12 [AK124901] -3.7778223 0.036767952 NM_144724 MARVELD2 Homo sapiens MARVEL domain containing 2 (MARVELD2), transcript variant 2, mRNA [NM_144724] -3.8595986 0.029283851 AK094842 C9orf47 Homo sapiens cDNA FLJ37523 fis, clone BRCAN2006401. [AK094842] -3.8840952 0.002220848 THC2649341 Homo sapiens microphthalmia-associated transcription factor (MITF), transcript variant 1, mRNA -3.8935199 0.006725097 NM_198159 MITF [NM 198159] -3.9286976 0.026826197 THC2683124 -3.9650528 0.023917872 NM_007371 BRD3 Homo sapiens bromodomain containing 3 (BRD3), mRNA [NM_007371] YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113). -4.037152 0.017674338 ENST00000325680 [Source:Uniprot/SWISSPROT;Acc:P49750] [ENST00000325680] -4.3704805 0.028742477 ENST00000327423 CDNA FLJ27434 fis, clone WMD09549. [Source:Uniprot/SPTREMBL;Acc:Q6ZNN1] [ENST00000327423] Homo sapiens Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal -4.828857 0.00282298 NM_015365 AMMECR1 region, gene 1 (AMMECR1), transcript variant 1, mRNA [NM 015365] -5.1513476 0.022277115 NM_033407 DOCK7 Homo sapiens dedicator of cytokinesis 7 (DOCK7), mRNA [NM_033407] -5.4790573 0.004988545 AK098270 AK098270 Homo sapiens cDNA FLJ40951 fis, clone UTERU2010124. [AK098270] Homo sapiens mitochondrial ribosomal protein L30 (MRPL30), nuclear gene encoding mitochondrial protein, -8.253523 0.021104716 NM_145212 MRPL30 transcript variant 1, mRNA [NM 145212] Table S8. Ingenuity Pathway Analysis: Canonical Pathways. 2 vs. 0.4 Gy irradiation

No overlap -Log(P -value) Ratio Downregulated No change Upregulated Molecules Canonical Pathways with dataset POLR2D, GRB2, GLS, CREBBP, PDPK1, GNG13, CREB5, STX1A, Huntington's Disease Signaling 2.41E00 6.36E-02 5/236 (2%) 0/236 (0%) 10/236 (4%) 221/236 (94%) UBD, HSPA8, GNB4, CAPN1, IGF1R, CAPN9, CASP10 TGFBR2, GRB2, MED1, ACOX1, ADCY4, CREBBP, PPARα/RXRα Activation 1.9E00 6.52E-02 7/184 (4%) 0/184 (0%) 5/184 (3%) 172/184 (93%) PRKAR2A, IL1B, RXRA, ACVR1C, TGS1, NCOA3 UBD, GABRB3, GAD1, GABA Receptor Signaling 1.76E00 9.09E-02 2/55 (4%) 0/55 (0%) 3/55 (5%) 50/55 (91%) SLC6A13, GABRB2 ZFYVE9, UBD, TGFBR2, TGF-β Signaling 1.73E00 8.14E-02 4/86 (5%) 0/86 (0%) 3/86 (3%) 79/86 (92%) BMPR1A, GRB2, CREBBP, ACVR1C Melanocyte Development and Pigmentation GRB2, MITF, TYR, ADCY4, 1.63E00 7.87E-02 3/89 (3%) 0/89 (0%) 4/89 (4%) 82/89 (92%) Signaling CREBBP, PRKAR2A, CREB5 CAPN1, PRKAR2A, CSNK1A1, Amyloid Processing 1.58E00 8.93E-02 2/56 (4%) 0/56 (0%) 3/56 (5%) 51/56 (91%) CAPN9, PSEN1 Complement System 1.57E00 1.11E-01 0/36 (0%) 0/36 (0%) 4/36 (11%) 32/36 (89%) C1R, C8A, C3AR1, C4B Riboflavin Metabolism 1.54E00 5.45E-02 2/55 (4%) 0/55 (0%) 1/55 (2%) 52/55 (95%) ACP2, TYR, SACM1L Notch Signaling 1.53E00 9.3E-02 2/43 (5%) 0/43 (0%) 2/43 (5%) 39/43 (91%) ADAM17, MFNG, RBPJ, PSEN1 GNB4, GRB2, CAV1, G Beta Gamma Signaling 1.51E00 5.98E-02 5/117 (4%) 0/117 (0%) 2/117 (2%) 110/117 (94%) PRKAR2A, PDPK1, GNG13, SOX4, UBD, TGFBR2, Wnt/β-catenin Signaling 1.47E00 6.06E-02 2/165 (1%) 0/165 (0%) 8/165 (5%) 155/165 (94%) PPP2R5C, WNT10A, CREBBP, CSNK1A1, WNT9A, ACVR1C, GNB4, PPP1R3D, PPP2R5C, Cardiac β-adrenergic Signaling 1.34E00 5.71E-02 3/140 (2%) 0/140 (0%) 5/140 (4%) 132/140 (94%) ADCY4, PRKAR2A, CACNA1C, GNG13, PPP1CB GSTP1, GRB2, CDKN1A, Prostate Cancer Signaling 1.27E00 6.25E-02 2/96 (2%) 0/96 (0%) 4/96 (4%) 90/96 (94%) CREBBP, PDPK1, CREB5 EIF2S3, GRB2, PDPK1, PPP1CB, EIF2 Signaling 1.25E00 6.25E-02 5/96 (5%) 0/96 (0%) 1/96 (1%) 90/96 (94%) EIF2AK2, EIF2S1 GRB2, ADCY4, CREBBP, RALB, CDK6, PRKAR2A, Molecular Mechanisms of Cancer 1.22E00 4.57E-02 12/372 (3%) 0/372 (0%) 5/372 (1%) 355/372 (95%) TGFBR2, BMPR1A, CDKN1A, RBPJ, GNA13, HIPK2, WNT1, PSEN1, CTNND1, CDC25A, FETUB, CREBBP, IL1B, APOC2, FXR/RXR Activation 1.17E00 6E-02 1/100 (1%) 0/100 (0%) 5/100 (5%) 94/100 (94%) SLC22A7, RXRA PPP1R3D, GRIN2C, CREBBP, Synaptic Long Term Potentiation 1.15E00 6.09E-02 2/115 (2%) 0/115 (0%) 5/115 (4%) 108/115 (94%) PRKAR2A, CACNA1C, PPP1CB, CREB5 NOV, GRB2, IGF1R, PRKAR2A, IGF-1 Signaling 1.11E00 6.12E-02 4/98 (4%) 0/98 (0%) 2/98 (2%) 92/98 (94%) PDPK1, IRS2 SCD, IL1B, APOC2, RXRA, LXR/RXR Activation 1.1E00 5.81E-02 2/86 (2%) 0/86 (0%) 3/86 (3%) 81/86 (94%) HADH PPP1R3D, PPP2R5C, ADCY4, CDK5 Signaling 1.09E00 6.38E-02 3/94 (3%) 0/94 (0%) 3/94 (3%) 88/94 (94%) CAPN1, PRKAR2A, PPP1CB CALR, GNB4, POLR2D, Androgen Signaling 1.05E00 4.83E-02 3/145 (2%) 0/145 (0%) 4/145 (3%) 138/145 (95%) CREBBP, PRKAR2A, GNG13, GNA13 NT5E, CDK6, CSNK1A1, Nicotinate and Nicotinamide Metabolism 1.04E00 4.41E-02 4/136 (3%) 0/136 (0%) 2/136 (1%) 130/136 (96%) EIF2AK2, HIPK1, SACM1L GSTP1, MED1, CDKN1A, Aryl Hydrocarbon Receptor Signaling 1.03E00 5.1E-02 4/157 (3%) 0/157 (0%) 4/157 (3%) 149/157 (95%) CDK6, IL1B, RXRA, NFE2L2, S1PR4, TGFBR2, WNT10A, Human Embryonic Stem Cell Pluripotency 1.02E00 4.86E-02 2/144 (1%) 0/144 (0%) 5/144 (3%) 137/144 (95%) BMPR1A, PDPK1, WNT9A, WNT1 Role of CHK Proteins in Cell Cycle Checkpoint 1E00 8.82E-02 2/34 (6%) 0/34 (0%) 1/34 (3%) 31/34 (91%) CDKN1A, RFC1, CDC25A Control Retinoic acid Mediated Apoptosis Signaling 1E00 6.82E-02 1/44 (2%) 0/44 (0%) 2/44 (5%) 41/44 (93%) TNFRSF10B, TNFSF10, RXRA PPP1R3D, PPP2R5C, ADCY4, Dopamine Receptor Signaling 9.95E-01 5.49E-02 3/91 (3%) 0/91 (0%) 2/91 (2%) 86/91 (95%) PRKAR2A, PPP1CB GRB2, CDKN1A, IGF1R, Glioma Signaling 9.86E-01 5.36E-02 3/112 (3%) 0/112 (0%) 3/112 (3%) 106/112 (95%) CAMK1G, CDK6, IGF2R GNB4, POLR2D, GRB2, CREB Signaling in Neurons 9.77E-01 4.64E-02 4/194 (2%) 0/194 (0%) 5/194 (3%) 185/194 (95%) ADCY4, CREBBP, PRKAR2A, GNG13, GNA13, CREB5 Glycosaminoglycan Degradation 9.71E-01 4.17E-02 1/72 (1%) 0/72 (0%) 2/72 (3%) 69/72 (96%) ALOX15, IDS, SULF2 Docosahexaenoic Acid (DHA) Signaling 9.43E-01 6.67E-02 2/45 (4%) 0/45 (0%) 1/45 (2%) 42/45 (93%) ALOX15, PDPK1, IL1B TNFSF11, MED1, CDKN1A, VDR/RXR Activation 9.22E-01 6.25E-02 3/80 (4%) 0/80 (0%) 2/80 (3%) 75/80 (94%) RXRA, NCOA3 Stress Pathway 9.11E-01 1.11E-01 1/18 (6%) 0/18 (0%) 1/18 (6%) 16/18 (89%) ATF6, EIF2S1 HSPA8, TGFBR2, TAF1, POLR2D, GRB2, MED1, Glucocorticoid Receptor Signaling 8.98E-01 4.29E-02 7/280 (3%) 0/280 (0%) 5/280 (2%) 268/280 (96%) CDKN1A, CREBBP, PBX1, IL1B, HLTF, NCOA3 TGFBR2, GNB4, GRB2, ADCY4, CREBBP, IGF1R, PRKAR2A, Cardiac Hypertrophy Signaling 8.92E-01 4.53E-02 3/243 (1%) 0/243 (0%) 8/243 (3%) 232/243 (95%) CACNA1C, GNG13, ATF6, GNA13 D-glutamine and D-glutamate Metabolism 8.9E-01 3.7E-02 0/27 (0%) 0/27 (0%) 1/27 (4%) 26/27 (96%) GLS PPP1R3D, GRB2, PTPN1, Insulin Receptor Signaling 8.79E-01 5.07E-02 5/138 (4%) 0/138 (0%) 2/138 (1%) 131/138 (95%) PRKAR2A, PDPK1, PPP1CB, IRS2 Role of Pattern Recognition Receptors in NLRP3, IL1B, EIF2AK2, EIF2S1, 8.71E-01 5.62E-02 2/89 (2%) 0/89 (0%) 3/89 (3%) 84/89 (94%) Recognition of Bacteria and Viruses C3AR1 PPP1R3D, PPP2R5C, GRB2, ERK/MAPK Signaling 8.52E-01 4.69E-02 4/192 (2%) 0/192 (0%) 5/192 (3%) 183/192 (95%) DUSP6, PLA2G1B, PRKAR2A, PPP1CB, MKNK2, CREB5 ARHGAP26, GRB2, CAPN1, FAK Signaling 8.23E-01 5.1E-02 3/98 (3%) 0/98 (0%) 2/98 (2%) 93/98 (95%) PDPK1, CAPN9 TAF1, POLR2D, GRB2, MED1, Signaling 8.23E-01 4.96E-02 4/121 (3%) 0/121 (0%) 2/121 (2%) 115/121 (95%) CREBBP, NCOA3 POLD3, POLR2D, POLE2, Pyrimidine Metabolism 7.82E-01 3.45E-02 7/232 (3%) 0/232 (0%) 1/232 (0%) 224/232 (97%) NT5E, CTPS2, NUDT2, DCTD, PRMT2, MED1, ADCY4, RAR Activation 7.64E-01 4.49E-02 6/178 (3%) 0/178 (0%) 2/178 (1%) 170/178 (96%) CREBBP, PRKAR2A, PDPK1, RXRA, HLTF Non-Small Cell Lung Cancer Signaling 7.5E-01 5.06E-02 4/79 (5%) 0/79 (0%) 0/79 (0%) 75/79 (95%) GRB2, CDK6, PDPK1, RXRA ARHGAP26, GRB2, CAPN1, Integrin Signaling 7.43E-01 4.43E-02 5/203 (2%) 0/203 (0%) 4/203 (2%) 194/203 (96%) MYLK2, RALB, ARPC4, CAV1, PPP1CB, CAPN9 GRB2, MED1, CREBBP, IL1B, PPAR Signaling 7.36E-01 4.95E-02 3/101 (3%) 0/101 (0%) 2/101 (2%) 96/101 (95%) RXRA BMPR1A, GRB2, CDKN1A, PTEN Signaling 7.22E-01 4.76E-02 4/105 (4%) 0/105 (0%) 1/105 (1%) 100/105 (95%) PDPK1, MAGI3 TGFBR2, PLA2G1B, IL1B, p38 MAPK Signaling 6.96E-01 5.26E-02 0/95 (0%) 0/95 (0%) 5/95 (5%) 90/95 (95%) MKNK2, CREB5 C1R, PLG, HP, ORM2, GRB2, Acute Phase Response Signaling 6.95E-01 4.52E-02 2/177 (1%) 0/177 (0%) 6/177 (3%) 169/177 (95%) PDPK1, IL1B, C4B CALR, TPM3, GRIN2C, TNNT3, Calcium Signaling 6.58E-01 3.88E-02 2/206 (1%) 0/206 (0%) 6/206 (3%) 198/206 (96%) CREBBP, CAMK1G, PRKAR2A, CREB5 TGFBR2, GNB4, WNT10A, Colorectal Cancer Metastasis Signaling 6.55E-01 4.05E-02 2/247 (1%) 0/247 (0%) 8/247 (3%) 237/247 (96%) GRB2, ADCY4, PRKAR2A, GNG13, WNT9A, WNT1, MMP19 Antiproliferative Role of Somatostatin Receptor GNB4, ADCY4, CDKN1A, 6.44E-01 4.94E-02 0/81 (0%) 0/81 (0%) 4/81 (5%) 77/81 (95%) 2 GNG13 Neuropathic Pain Signaling In Dorsal Horn KCNN1, KCNN4, GRIN2C, 6.23E-01 4.81E-02 2/104 (2%) 0/104 (0%) 3/104 (3%) 99/104 (95%) Neurons CAMK1G, PRKAR2A GRB2, ADCY4, CREBBP, GNRH Signaling 6.23E-01 4.2E-02 2/143 (1%) 0/143 (0%) 4/143 (3%) 137/143 (96%) PRKAR2A, GNRH2, CREB5 Role of BRCA1 in DNA Damage Response 6.21E-01 5.66E-02 2/53 (4%) 0/53 (0%) 1/53 (2%) 50/53 (94%) CDKN1A, RFC1, HLTF BMPR1A, GRB2, CREBBP, BMP signaling pathway 6.17E-01 5E-02 3/80 (4%) 0/80 (0%) 1/80 (1%) 76/80 (95%) PRKAR2A DDX25, POLR2D, POLE2, ADCY4, DLG2, RUVBL1, GUK1, Purine Metabolism 6.16E-01 2.95E-02 9/440 (2%) 0/440 (0%) 4/440 (1%) 427/440 (97%) CASK, NUDT2, POLD3, C22ORF30, NT5E, HLTF PFKFB3, PPP2R5C, PRKAR2A, AMPK Signaling 6.13E-01 3.68E-02 5/163 (3%) 0/163 (0%) 1/163 (1%) 157/163 (96%) PDPK1, IRS2, HLTF ATM Signaling 6.04E-01 5.77E-02 1/52 (2%) 0/52 (0%) 2/52 (4%) 49/52 (94%) CDKN1A, CREB5, CDC25A KCNN1, KCNN4, ADCY4, Cellular Effects of Sildenafil (Viagra) 5.93E-01 3.97E-02 2/151 (1%) 0/151 (0%) 4/151 (3%) 145/151 (96%) PRKAR2A, CACNA1C, PPP1CB Taurine and Hypotaurine Metabolism 5.74E-01 4.26E-02 1/47 (2%) 0/47 (0%) 1/47 (2%) 45/47 (96%) GAD1, GGT7 Mitotic Roles of Polo-Like Kinase 5.59E-01 4.84E-02 2/62 (3%) 0/62 (0%) 1/62 (2%) 59/62 (95%) PPP2R5C, PLK2, CDC25A PIP5K1A, ARPC4, PFN2, Regulation of Actin-based Motility by Rho 5.54E-01 4.3E-02 3/93 (3%) 0/93 (0%) 1/93 (1%) 89/93 (96%) PPP1CB Circadian Rhythm Signaling 5.48E-01 5.71E-02 0/35 (0%) 0/35 (0%) 2/35 (6%) 33/35 (94%) GRIN2C, CREB5 Cell Cycle: G1/S Checkpoint Regulation 5.3E-01 5.08E-02 2/59 (3%) 0/59 (0%) 1/59 (2%) 56/59 (95%) CDKN1A, CDK6, CDC25A Role of NANOG in Mammalian Embryonic WNT10A, BMPR1A, GRB2, 5.28E-01 4.39E-02 2/114 (2%) 0/114 (0%) 3/114 (3%) 109/114 (96%) Stem Cell Pluripotency WNT9A, WNT1 G Protein Signaling Mediated by Tubby 5.11E-01 4.88E-02 0/41 (0%) 0/41 (0%) 2/41 (5%) 39/41 (95%) GNB4, GNG13 TR/RXR Activation 5.09E-01 4.26E-02 2/94 (2%) 0/94 (0%) 2/94 (2%) 90/94 (96%) HP, MED1, RXRA, NCOA3 VEGF Signaling 5.09E-01 4.12E-02 4/97 (4%) 0/97 (0%) 0/97 (0%) 93/97 (96%) EIF2S3, GRB2, EIF2S1, ELAVL1 Death Receptor Signaling 5.04E-01 4.69E-02 1/64 (2%) 0/64 (0%) 2/64 (3%) 61/64 (95%) TNFRSF10B, TNFSF10, CASP10 Glutamate Receptor Signaling 5.04E-01 4.29E-02 1/70 (1%) 0/70 (0%) 2/70 (3%) 67/70 (96%) GRIN2C, GLS, SLC1A1 Nucleotide Excision Repair Pathway 4.94E-01 5.71E-02 2/35 (6%) 0/35 (0%) 0/35 (0%) 33/35 (94%) POLR2D, RAD23B Glutamate Metabolism 4.94E-01 2.56E-02 0/78 (0%) 0/78 (0%) 2/78 (3%) 76/78 (97%) GLS, GAD1 IL-10 Signaling 4.91E-01 4.29E-02 1/70 (1%) 0/70 (0%) 2/70 (3%) 67/70 (96%) IL10RB, IL10RA, IL1B Propanoate Metabolism 4.91E-01 2.31E-02 3/130 (2%) 0/130 (0%) 0/130 (0%) 127/130 (98%) SUCLA2, ACAT1, PCCB Butanoate Metabolism 4.79E-01 2.26E-02 2/133 (2%) 0/133 (0%) 1/133 (1%) 130/133 (98%) GAD1, ACAT1, HADH WHSC1L1, PPP2R5C, ACAT1, Degradation 4.71E-01 2.56E-02 6/234 (3%) 0/234 (0%) 0/234 (0%) 228/234 (97%) MLL3, HADH, PSEN1 Nucleotide Sugars Metabolism 4.7E-01 1.35E-02 1/74 (1%) 0/74 (0%) 0/74 (0%) 73/74 (99%) ALOX15 Fatty Acid Biosynthesis 4.7E-01 1.96E-02 1/51 (2%) 0/51 (0%) 0/51 (0%) 50/51 (98%) PCCB Synthesis and Degradation of Ketone Bodies 4.7E-01 5.26E-02 1/19 (5%) 0/19 (0%) 0/19 (0%) 18/19 (95%) ACAT1 MED1, CDKN1A, TNFRSF10B, p53 Signaling 4.68E-01 4.49E-02 2/89 (2%) 0/89 (0%) 2/89 (2%) 85/89 (96%) HIPK2 JAK/Stat Signaling 4.66E-01 4.69E-02 1/64 (2%) 0/64 (0%) 2/64 (3%) 61/64 (95%) GRB2, CDKN1A, PTPN1 ADAM17, GRB2, PDPK1, Neuregulin Signaling 4.58E-01 4E-02 3/100 (3%) 0/100 (0%) 1/100 (1%) 96/100 (96%) PSEN1 GRIN2C, CAPN1, CACNA1C, Amyotrophic Lateral Sclerosis Signaling 4.58E-01 3.57E-02 0/112 (0%) 0/112 (0%) 4/112 (4%) 108/112 (96%) CAPN9 Basal Cell Carcinoma Signaling 4.55E-01 4.41E-02 0/68 (0%) 0/68 (0%) 3/68 (4%) 65/68 (96%) WNT10A, WNT9A, WNT1 GNB4, GRB2, GRIN2C, ARPC4, Ephrin Receptor Signaling 4.44E-01 3.52E-02 3/199 (2%) 0/199 (0%) 4/199 (2%) 192/199 (96%) GNG13, GNA13, CREB5 GNB4, ADCY4, PRKAR2A, α-Adrenergic Signaling 4.39E-01 3.74E-02 1/107 (1%) 0/107 (0%) 3/107 (3%) 103/107 (96%) GNG13 PIP5K1A, GRB2, MYLK2, Actin Cytoskeleton Signaling 4.35E-01 3.38E-02 6/237 (3%) 0/237 (0%) 2/237 (1%) 229/237 (97%) ARPC4, PFN2, PPP1CB, WASF2, GNA13 HTR2C, GRB2, ADCY4, DUSP6, G-Protein Coupled Receptor Signaling 4.35E-01 3.67E-02 5/218 (2%) 0/218 (0%) 3/218 (1%) 210/218 (96%) PRKAR2A, PDPK1, EDNRA, CREB5 FcγRIIB Signaling in B Lymphocytes 4.31E-01 3.57E-02 2/56 (4%) 0/56 (0%) 0/56 (0%) 54/56 (96%) GRB2, PDPK1 GSTP1, PPP2R5C, MED1, Xenobiotic Metabolism Signaling 4.23E-01 3.4E-02 5/294 (2%) 0/294 (0%) 5/294 (2%) 284/294 (97%) CREBBP, CAMK1G, IL1B, FMO1, NDST4, RXRA, NFE2L2 Neurotrophin/TRK Signaling 4.22E-01 3.85E-02 2/78 (3%) 0/78 (0%) 1/78 (1%) 75/78 (96%) GRB2, PDPK1, CREB5 T Helper Cell Differentiation 4.17E-01 4.88E-02 1/41 (2%) 0/41 (0%) 1/41 (2%) 39/41 (95%) IL10RB, IL10RA Cell Cycle: G2/M DNA Damage Checkpoint 4.17E-01 4.65E-02 0/43 (0%) 0/43 (0%) 2/43 (5%) 41/43 (95%) UBD, CDKN1A Regulation Folate Biosynthesis 4.17E-01 1.25E-02 1/80 (1%) 0/80 (0%) 0/80 (0%) 79/80 (99%) DDX6 Growth Hormone Signaling 4.11E-01 4.11E-02 2/73 (3%) 0/73 (0%) 1/73 (1%) 70/73 (96%) IGF1R, PDPK1, ONECUT1 TGFBR2, GRB2, CDKN1A, Chronic Myeloid Leukemia Signaling 4.04E-01 3.81E-02 2/105 (2%) 0/105 (0%) 2/105 (2%) 101/105 (96%) CDK6 Role of PKR in Interferon Induction and 4.04E-01 4.35E-02 2/46 (4%) 0/46 (0%) 0/46 (0%) 44/46 (96%) EIF2AK2, EIF2S1 Antiviral Response CCR5 Signaling in Macrophages 4.01E-01 3.3E-02 0/91 (0%) 0/91 (0%) 3/91 (3%) 88/91 (97%) GNB4, CCL4, GNG13 , Leucine and Degradation 4.01E-01 2.7E-02 3/111 (3%) 0/111 (0%) 0/111 (0%) 108/111 (97%) ACAT1, PCCB, HADH PXR/RXR Activation 3.91E-01 3.49E-02 2/86 (2%) 0/86 (0%) 1/86 (1%) 83/86 (97%) SCD, PRKAR2A, RXRA FLT3 Signaling in Hematopoietic Progenitor 3.91E-01 4.11E-02 2/73 (3%) 0/73 (0%) 1/73 (1%) 70/73 (96%) GRB2, PDPK1, CREB5 Cells GNB4, ADCY4, PRKAR2A, Relaxin Signaling 3.86E-01 3.38E-02 2/148 (1%) 0/148 (0%) 3/148 (2%) 143/148 (97%) GNG13, GNA13 Renal Cell Carcinoma Signaling 3.81E-01 4.11E-02 1/73 (1%) 0/73 (0%) 2/73 (3%) 70/73 (96%) UBD, GRB2, CREBBP Hepatic Fibrosis / Hepatic Stellate Cell TGFBR2, IGF1R, IL10RA, 3.79E-01 3.7E-02 1/135 (1%) 0/135 (0%) 4/135 (3%) 130/135 (96%) Activation EDNRA, IL1B Melanoma Signaling 3.78E-01 4.35E-02 1/46 (2%) 0/46 (0%) 1/46 (2%) 44/46 (96%) MITF, CDKN1A Fatty Acid Elongation in Mitochondria 3.73E-01 2.22E-02 1/45 (2%) 0/45 (0%) 0/45 (0%) 44/45 (98%) HADH Phenylalanine, Tyrosine and 3.73E-01 1.49E-02 1/67 (1%) 0/67 (0%) 0/67 (0%) 66/67 (99%) FARSB Biosynthesis Sphingolipid Metabolism 3.72E-01 3.57E-02 3/112 (3%) 0/112 (0%) 1/112 (1%) 108/112 (96%) ARSD, UGCG, SULF2, SACM1L GNB4, GRB2, ADCY4, Thrombin Signaling 3.7E-01 3.43E-02 3/204 (1%) 0/204 (0%) 4/204 (2%) 197/204 (97%) CAMK1G, PDPK1, GNG13, GNA13 SEMA3E, ADAM17, GRB2, PFN2, PRKAR2A, GNG13, Axonal Guidance Signaling 3.7E-01 3.21E-02 7/405 (2%) 0/405 (0%) 6/405 (1%) 392/405 (97%) WNT9A, SEMA3A, GNB4, WNT10A, ARPC4, GNA13, WNT1 PDGF Signaling 3.63E-01 3.8E-02 3/79 (4%) 0/79 (0%) 0/79 (0%) 76/79 (96%) GRB2, CAV1, EIF2AK2 PIP5K1A, CDK6, CSNK1A1, Inositol Phosphate Metabolism 3.59E-01 2.84E-02 4/176 (2%) 0/176 (0%) 1/176 (1%) 171/176 (97%) EIF2AK2, HIPK1 Role of RIG1-like Receptors in Antiviral Innate 3.55E-01 3.92E-02 1/51 (2%) 0/51 (0%) 1/51 (2%) 49/51 (96%) CREBBP, CASP10 Immunity Fructose and Mannose Metabolism 3.55E-01 1.36E-02 1/147 (1%) 0/147 (0%) 1/147 (1%) 145/147 (99%) PFKFB3, SACM1L Nitric Oxide Signaling in the Cardiovascular 3.54E-01 3.26E-02 2/92 (2%) 0/92 (0%) 1/92 (1%) 89/92 (97%) CAV1, PRKAR2A, CACNA1C System S1PR4, ADCY4, GNA13, Sphingosine-1-phosphate Signaling 3.49E-01 3.54E-02 2/113 (2%) 0/113 (0%) 2/113 (2%) 109/113 (96%) CASP10 Chemokine Signaling 3.45E-01 3.9E-02 0/77 (0%) 0/77 (0%) 3/77 (4%) 74/77 (96%) CCL4, CAMK1G, PPP1CB ADCY4, PRKAR2A, IL1B, Hepatic Cholestasis 3.39E-01 3.03E-02 2/165 (1%) 0/165 (0%) 3/165 (2%) 160/165 (97%) SLC22A7, RXRA Cardiomyocyte Differentiation via BMP 3.35E-01 5E-02 1/20 (5%) 0/20 (0%) 0/20 (0%) 19/20 (95%) BMPR1A Receptors PLD4, GRB2, ADCY4, Endothelin-1 Signaling 3.33E-01 3.76E-02 5/186 (3%) 0/186 (0%) 2/186 (1%) 179/186 (96%) PLA2G1B, EDNRA, GNA13, GSTP1, ACOX1, IL1B, FMO1, LPS/IL-1 Mediated Inhibition of RXR Function 3.22E-01 3.41E-02 3/205 (1%) 0/205 (0%) 4/205 (2%) 198/205 (97%) APOC2, NDST4, RXRA Keratan Sulfate Biosynthesis 3.22E-01 3.64E-02 1/55 (2%) 0/55 (0%) 1/55 (2%) 53/55 (96%) B4GALT1, NDST4 Lipid Antigen Presentation by CD1 3.18E-01 4.55E-02 0/22 (0%) 0/22 (0%) 1/22 (5%) 21/22 (95%) CALR PPP2R5C, ADCY4, IGF1R, Synaptic Long Term Depression 3.09E-01 3.05E-02 2/164 (1%) 0/164 (0%) 3/164 (2%) 159/164 (97%) PLA2G1B, GNA13 NDUFA10 (includes EG:4705), Oxidative Phosphorylation 3.09E-01 3.01E-02 4/166 (2%) 0/166 (0%) 1/166 (1%) 161/166 (97%) FAM63B, ATP6V1A, MEGF11, ATP6V1B2 DNA Methylation and Transcriptional 3.03E-01 4.35E-02 1/23 (4%) 0/23 (0%) 0/23 (0%) 22/23 (96%) RBBP4 Repression Signaling Aldosterone Signaling in Epithelial Cells 2.98E-01 3.06E-02 3/98 (3%) 0/98 (0%) 0/98 (0%) 95/98 (97%) HSPA8, PIP5K1A, PDPK1 TNFSF11, BMPR1A, CREBBP, NF-κB Signaling 2.93E-01 3.36E-02 3/149 (2%) 0/149 (0%) 2/149 (1%) 144/149 (97%) IL1B, EIF2AK2 Factors Promoting Cardiogenesis in Vertebrates 2.9E-01 3.37E-02 2/89 (2%) 0/89 (0%) 1/89 (1%) 86/89 (97%) TGFBR2, BMPR1A, ACVR1C GNB4, PLA2G1B, GNG13, CCR3 Signaling in Eosinophils 2.89E-01 3.28E-02 0/122 (0%) 0/122 (0%) 4/122 (3%) 118/122 (97%) PPP1CB Stilbene, Coumarine and Lignin Biosynthesis 2.88E-01 2.56E-02 1/78 (1%) 0/78 (0%) 1/78 (1%) 76/78 (97%) C22ORF30, TYR Endometrial Cancer Signaling 2.76E-01 3.51E-02 2/57 (4%) 0/57 (0%) 0/57 (0%) 55/57 (96%) GRB2, PDPK1 Maturity Onset Diabetes of Young (MODY) 2.74E-01 3.23E-02 0/31 (0%) 0/31 (0%) 1/31 (3%) 30/31 (97%) CACNA1C Signaling Aminoacyl-tRNA Biosynthesis 2.74E-01 1.2E-02 1/83 (1%) 0/83 (0%) 0/83 (0%) 82/83 (99%) FARSB PPP2R5C, GRB2, CDKN1A, PI3K/AKT Signaling 2.65E-01 2.94E-02 3/136 (2%) 0/136 (0%) 1/136 (1%) 132/136 (97%) PDPK1 Apoptosis Signaling 2.63E-01 3.23E-02 1/93 (1%) 0/93 (0%) 2/93 (2%) 90/93 (97%) CAPN1, CAPN9, CASP10 Lymphotoxin β Receptor Signaling 2.59E-01 3.28E-02 1/61 (2%) 0/61 (0%) 1/61 (2%) 59/61 (97%) CREBBP, PDPK1 Thrombopoietin Signaling 2.59E-01 3.23E-02 2/62 (3%) 0/62 (0%) 0/62 (0%) 60/62 (97%) GRB2, IRS2 TREM1 Signaling 2.51E-01 2.9E-02 1/69 (1%) 0/69 (0%) 1/69 (1%) 67/69 (97%) GRB2, IL1B Myc Mediated Apoptosis Signaling 2.44E-01 3.33E-02 1/60 (2%) 0/60 (0%) 1/60 (2%) 58/60 (97%) GRB2, IGF1R Primary Immunodeficiency Signaling 2.37E-01 4.76E-02 1/63 (2%) 0/63 (0%) 2/63 (3%) 60/63 (95%) GRB2, IGH@, RAG1 IL-22 Signaling 2.28E-01 3.7E-02 1/27 (4%) 0/27 (0%) 0/27 (0%) 26/27 (96%) IL10RB Methionine Metabolism 2.28E-01 1.25E-02 1/80 (1%) 0/80 (0%) 0/80 (0%) 79/80 (99%) AMD1 Citrate Cycle 2.18E-01 1.69E-02 1/59 (2%) 0/59 (0%) 0/59 (0%) 58/59 (98%) SUCLA2 Sonic Hedgehog Signaling 2.08E-01 3.23E-02 1/31 (3%) 0/31 (0%) 0/31 (0%) 30/31 (97%) PRKAR2A Table S9. Ingenuity Pathway Analysis: Functions, 2 vs. 0.4 Gy irradiation

Functions P -value Molecules SLC25A13, CLN3, PRMT2, CLN8, GLS, PRMT3, TYR, FOLR2, SLC6A19, PDPK1, Amino Acid Metabolism 2.23E-04-3.39E-02 SLC1A1, SLC6A13, STX1A, SLC38A2, ADH5 (includes EG:128), PRMT7, SLC43A2, GAD1, IDO1, IL1B, PSEN1 SCD, CLN3, SLC25A13, CLN8, ACOX1, FOLR2, SLC6A19, SLC1A1, STX1A, Molecular Transport 2.23E-04-3.39E-02 SLC6A13, SLC38A2, PLG, ADH5 (includes EG:128), TGFBR2, SLC43A2, B4GALT1, KISS1, IL1B, SLC35B4, TPMT, PSEN1 SCD, CLN8, MFNG, PRMT3, UGCG, FOLR2, PDPK1, SLC6A13, GABRB2, SACM1L, ADH5 (includes EG:128), TGFBR2, AMD1, CAV1, OAZ1, KISS1, NFE2L2, TPMT, CLN3, SLC25A13, PRMT2, TYR, GLS, ACOX1, PLA2G1B, Small Molecule Biochemistry 2.23E-04-3.39E-02 CACNA1C, SLC6A19, SLC1A1, DCTD, STX1A, SLC38A2, PLG, PRMT7, SLC43A2, B4GALT1, NT5E, GAD1, ACAT1, IL1B, EDNRA, IDO1, SLC35B4, PSEN1 CENPF, NRL, CLN8, PLK3, FBXW7, PDPK1, TGFBR2, CAV1, IRS2, GNA13, KLF2, CDC25A, ZFYVE9, SMN2, EWSR1, MITF, POU4F1, TNFRSF10B, RALB, CACNA1C, NCOA3, CNTN2, UBD, PIP5K1A, RXRA, WNT1, RBBP4, P2RX1, Cell Morphology 2.89E-04-3.39E-02 FKBP1A, UGCG, TNFSF10, EIF2S1, AMD1, MOV10L1, IGF1R, HGS, NFE2L2, ACVR1C, SEMA3E, CLN3, TNFSF11, TYR, PFN2, IGF2R, PLG, SEMA3A, TPM3, LAMA4, CDKN1A, IL1B, EDNRA, SORBS2, CDC42SE2, EIF2AK2, NDST2, PSEN1, CTNND1 SPTBN1, ALOX15, SMN2, TNFSF11, BARHL1, ACOX1, CREBBP, SLC12A7, Cellular Compromise 3.67E-04-3.39E-02 TNFSF10, SLC1A1, ROM1, UBD, PLG, TGFBR2, LAMA4, CDKN1A, CAV1, IL1B, SORBS2, PSEN1 PLG, BBS4, CLN8, CDKN1A, CDH23, CAV1, TNFSF10, FKBP1A, EIF2AK2, Cellular Function and Maintenance 7.13E-04-3.39E-02 EIF2S1 SCD, GSTP1, PLK3, TNFSF10, FBXW7, PDPK1, DICER1, EIF2S1, TGFBR2, AMD1, IGF1R, CAV1, HS6ST2, IRS2, GNA13, KLF2, HGS, FBRS, TNFSF11, Connective Tissue Development and Function 7.16E-04-3.39E-02 EWSR1, GRB2, KDM2B, TNFRSF10B, CREBBP, CDK6, PLG, NT5E, CAPN1, CDKN1A, IL1B, CDC42SE2, EIF2AK2, WASF2, WNT1, PSEN1, CTNND1 NRL, EIF4EBP2, PDPK1, TNFSF10, ATF6, GNRH2, EIF2S1, TGFBR2, GPR4, MYF6, CAV1, GNA13, HIPK2, KLF2, NFE2L2, HGS, CALR, TNFSF11, PRMT2, Gene Expression 1.03E-03-3.39E-02 NLRP3, EWSR1, MITF, GRB2, MED1, CREBBP, PRKAR2A, NFKBIZ, NCOA3, PLG, DDX6, RUNX1T1, CDKN1A, TEP1, SP100, EEF1A1, IL1B, RBPJ, EIF2AK2, RXRA, WNT1, TEF PLG, EIF2S3, DDX6, DDX25, EIF4EBP2, EEF1A1, CAV1, PDPK1, IL1B, TNFSF10, Protein Synthesis 1.03E-03-3.13E-02 EIF2AK2, EIF2S1 Auditory Disease 1.15E-03-1.15E-03 BARHL1, SLC12A7 PLK3, ELAVL1, SERPINB2, PTPRO, CAV1, IRS2, SMG1, CD274, GNA13, HIPK2, HIPK1, CASP10, NPAT, MED1, MOAP1, POU4F1, RALB, TNFRSF10B, CREBBP, CACNA1C, UBD, HSPA8, RUNX1T1, CAPN1, SPANXB2, RXRA, WNT1, SPTBN1, ADAM17, PHLDA2, DUSP6, TNFSF10, C1R, C9ORF86, AMD1, MYF6, HOXA5, CAMK1G, LAMP1, IGF1R, KISS1, LETM2, HGS, ACVR1C, NFE2L2, ALOX15, VPS18, TNFSF11, CLN3, PPP1R8, GRB2, CASK, IGF2R, SEMA3A, HP, NOV, TRPM7, CDKN1A, XAF1, SORBS2, RYK, NTSR1, PSEN1, CTNND1, GSTP1, PRPF19, VPRBP, CSNK1A1, NLRP1, PBX1, PDPK1, FBXW7, GNRH2, IL8RA, Cancer 1.15E-03-3.39E-02 DICER1, TGFBR2, USP7, GPR4, GRIN2C, TNNT3, KLF2, CDC25A, SCN5A, SOX4, SSTR4, EWSR1, POLE2, CDK6, SLC12A7, SLC1A1, AGR2, DDX17, NCOA3, PIP5K1A, DDX6, GAD1, RAG1, RBBP6 (includes EG:5930), RBBP4, SCD, SERPINA6, KCNK3, ATF5, UGCG, ATF6, MLL3, GABRB2, TRA2A, GABRB3, BMPR1A, PLK2, ZNF24 (includes EG:7572), PTPN1, OAZ1, RAD23B, MMP19, TPMT, PPP1R9A, BBS4, CALR, NLRP3, PPP2R5C, BGN, RPL23, NFKBIZ, FDXR, PLG, PPP1R3D, ACOT2, LAMA4, EEF1A1, ACAT1, EDNRA, IL1B, SLC19A2, EIF2AK2, CLEC10A

Cardiovascular System Development and CALR, TNFSF11, MYLK2, P2RX1, FKBP1A, CACNA1C, PLG, HTR2C, BMPR1A, 1.15E-03-3.39E-02 Function CAV1, EDNRA, IL1B, RXRA, NFE2L2, MYBPC3 CENPF, PLK3, ROM1, ELAVL1, SERPINB2, PTPRO, CAV1, SMG1, IRS2, CD274, GNA13, HIPK1, HIPK2, CASP10, MED1, MITF, POU4F1, MOAP1, TNFRSF10B, CREBBP, RALB, CACNA1C, RFC1, UBD, HSPA8, RUNX1T1, CCL4, CAPN1, RXRA, WNT1, PHLDA2, DUSP6, TNFSF10, FKBP1A, HOXA5, CAMK1G, LAMP1, IGF1R, ALX4, NSMCE1, ACVR1C, NFE2L2, ALOX15, TNFSF11, CLN3, THG1L, PPP1R8, GRB2, TYR, FAIM2, CASK, IGF2R, RNF216, SEMA3A, CDKN1A, XAF1, Cell Death 1.15E-03-3.39E-02 SORBS2, PSEN1, NTSR1, GSTP1, PRPF19, BARHL1, CLN8, VPRBP, PBX1, NLRP1, CSNK1A1, FBXW7, PDPK1, DICER1, PDCD7, TGFBR2, USP7, GRIN2C, KLF2, CDC25A, SOX4, SMN2, EWSR1, CDK6, SLC1A1, NCOA3, SERINC3, RAG1, IDO1, RBBP6 (includes EG:5930), RBBP4, KCNK3, ATF5, ITM2B, AKTIP, UGCG, ATF6, ERC1, EIF2S1, BMPR1A, PLK2, PTPN1, OAZ1, RAD23B, PPP1R9A, BBS4, CALR, PRMT2, NLRP3, PPP2R5C, BGN, DLX2, NFKBIZ, FDXR, PLG, EMP1, PPP1R3D, TPM3, B4GALT1, EEF1A1, IL1B, EIF2AK2, MYBPC3

CENPF, ELAVL1, SERPINB2, PTPRO, CAV1, CD274, IRS2, HIPK1, HIPK2, MITF, MED1, POU4F1, TNFRSF10B, RALB, CREBBP, RUNX1T1, CCL4, CAPN1, IL10RA, ULBP2, WASF2, RXRA, C3AR1, WNT1, REG1B, SPTBN1, ADAM17, BATF, FKBP1A, TNFSF10, AMD1, MYF6, CRIP2, IL34, MOV10L1, HOXA5, IGF1R, KISS1, HGS, ACVR1C, FBRS, CLN3, TNFSF11, THG1L, PPP1R8, GRB2, TYR, IGF2R, SEMA3A, NOV, TRPM7, CDKN1A, RBPJ, CTNND1, PSEN1, GSTP1, Cellular Growth and Proliferation 1.15E-03-3.39E-02 PRPF19, VPRBP, PBX1, CSNK1A1, PDPK1, GNRH2, DICER1, IL8RA, TGFBR2, AMBN, KLF2, CDC25A, SOX4, ELN, SSTR4, EWSR1, CDK6, NCOA3, DDX17, SERINC3, GAD1, RAG1, IDO1, UHMK1, RBBP4, KCNN4, ATF5, UGCG, TRA2A, BMPR1A, PTPN1, OAZ1, HS6ST2, TPMT, MMP19, CALR, BGN, PLA2G1B, FDXR, EMP1, PLG, B4GALT1, TPM3, LAMA4, NT5E, ESM1, IL1B, EDNRA, EIF2AK2 TNFSF11, PRPF19, MITF, MED1, GRB2, PBX1, TGFBR2, MYF6, TCEB3, IGF1R, Embryonic Development 1.15E-03-3.39E-02 RBPJ, ALX4, EDNRA, HIPK2, HIPK1, RXRA, RYK PLG, TGFBR2, SPTBN1, NT5E, MED1, ACOX1, CDKN1A, IGF1R, TNFSF10, Hepatic System Development and Function 1.15E-03-1.56E-02 IL1B, C3AR1 PLG, SCD, B4GALT1, ACOX1, PLA2G1B, ACAT1, EDNRA, UGCG, KISS1, IL1B, Lipid Metabolism 1.15E-03-3.39E-02 SACM1L CENPF, SLC25A26, NRL, DDX25, DLG2, RABGAP1L, ROM1, CREB5, RTF1, GNB4, PEX16, KCNIP2, JPH2, CD274, GNA13, HIPK1, HIPK2, C4B, TSHZ2, KCNQ5, ZCCHC4, ORM2, DDX31, MITF, POU4F1, TNFRSF10B, CREBBP, RALB, CACNA1C, LARP4, SUSD4, NDST4, DONSON, GSTCD, HSPA8, CCL4, CAPN1, IL10RA, C18ORF45, RXRA, PRICKLE1, C3AR1, C20ORF43, TSNARE1, DUSP6, TNFSF10, FKBP1A, CSMD2, ODZ3, C1R, MYO1B, LAMP1, IGF1R, VPS13B, RBM19, NFE2L2, ALOX15, CLN3, ACOX1, TYR, PFN2, ZNF284, RNF216, SEMA3A, HP, TRPM7, CAP2, CTNNBL1, CDKN1A, SORBS2, ADAMTSL1, MEGF11, RUFY3, PSEN1, AFAP1L1, NAV2 (includes EG:89797), BARHL1, ARHGAP26, VPRBP, PBX1, NLRP1, FBXW7, PDPK1, DICER1, IL8RA, SACM1L, Neurological Disease 1.15E-03-3.39E-02 GGA2, TGFBR2, GRIN2C, TMTC2, COL11A2, AIM1 (includes EG:202), SCN5A, SOX4, G3BP2, SMN2, SSTR4, MARVELD2, EWSR1, ACP2, POLE2, CDK6, SLC12A7, SLC1A1, STX1A, ATP6V1A, NCOA3, PIP5K1A, TAF1, CPNE5, GAD1, PUS10, RAG1, IDO1, UHMK1, FLJ22536, LRRC38, SCD, KCNK3, ITM2B, CDH23, PPP1CB, LOC286467, UGCG, ERC1, APOC2, EIF2S1, SLC6A13, FARSB, GABRB2, HTR2C, SUCLA2, GABRB3, USP13 (includes EG:8975), PLK2, PTPN1, CNTNAP5 (includes EG:129684), HS6ST2, OAZ1, SLC16A12, BBS4, SEMA3E, CALR, LRRC2, LMO7, PPP2R5C, BGN, PRKAR2A, PLA2G1B, DLX2, SNX27, IGHA2, PDK3, FDXR, HNRNPCL1, PLG, GPR56, TPM3, B4GALT1, DIP2C, BBX, ACAT1, EEF1A1, EDNRA, ZNF141, IL1B, EIF2AK2, SLC9A8, HADH, ATP6V1B2, RIN2

PBX1, DICER1, WNT9A, TGFBR2, ADH5 (includes EG:128), AMD1, MYF6, BMPR1A, PLK2, HOXA5, PTPN1, CAV1, IGF1R, JPH2, ALX4, KISS1, IRS2, Organismal Development 1.15E-03-3.39E-02 GNA13, NFE2L2, ACVR1C, KLF2, RAD23B, CALR, TNFSF11, CHD8, MED1, NPAT, MITF, ACOX1, POU4F1, CDK6, DLX2, IGF2R, ONECUT1, NCOA3, PLG, CCL4, KDM5D, LAMA4, IL1B, EDNRA, IFT52, RBPJ, WASF2, PSEN1 RNA Post-Transcriptional Modification 1.15E-03-3.39E-02 DDX25, TEP1, EIF2AK2, DDX17 Reproductive System Development and PLG, ZFYVE9, TNFSF11, MED1, GAD1, CAV1, KISS1, IL1B, IRS2, EIF2AK2, 1.15E-03-3.39E-02 Function WNT1 Respiratory Disease 1.15E-03-3.39E-02 CAV1, TNFSF10, PDPK1 ELN, ALOX15, MED1, MYLK2, FKBP1A, DLX2, PLG, TGFBR2, SEMA3A, MYF6, Tissue Development 1.15E-03-3.39E-02 CAV1, ALX4, EDNRA, HIPK2, HIPK1, RXRA, MYBPC3, RYK

ELN, SCD, CREBBP, TNFSF10, DICER1, ONECUT1, PLG, MYF6, NT5E, Tissue Morphology 1.15E-03-3.39E-02 CDKN1A, CAV1, IGF1R, IL1B, RBPJ, IRS2, HIPK1, HIPK2, NFE2L2, KLF2, WNT1, PSEN1 SPTBN1, CENPF, SCD, CLN8, WASF3, PDPK1, GEMIN5 (includes EG:25929), TNFSF10, ERC1, HTR2C, PTPN1, GEMIN8, CAV1, KISS1, GNA13, KLF2, HGS, Cellular Assembly and Organization 1.16E-03-3.39E-02 ZFYVE9, CALR, ELN, CLN3, ACP2, POU4F1, TYR, PFN2, STX1A, HILS1, PLG, SEMA3A, TPM3, LAMA4, CAPN1, CDKN1A, EDNRA, IL1B, RXRA, C3AR1, RBBP4, CTNND1, MYBPC3, PSEN1 CENPF, VPRBP, ATF5, MYLK2, CSNK1A1, TNFSF10, FKBP1A, DICER1, ELAVL1, SACM1L, MYF6, PTPRO, PLK2, MOV10L1, TCEB3, CAV1, IGF1R, CD274, IRS2, HIPK2, CDC25A, CALR, ALOX15, VPS18, SSTR4, EWSR1, Cell Cycle 1.22E-03-3.39E-02 PPP2R5C, MITF, NPAT, GRB2, KDM2B, CREBBP, CDK6, RPL23, NCOA3, HSPA8, PLG, UBD, TAF1, RUNX1T1, CDKN1A, IL1B, UHMK1, EIF2AK2, RXRA, WNT1, PSEN1, CTNND1 PRPF19, VPRBP, DUSP6, PBX1, TNFSF10, UGCG, ELAVL1, TGFBR2, PTPRO, PLK2, PTPN1, CAMK1G, IGF1R, CAV1, CDC25A, PPP1R9A, VPS18, TNFSF11, Reproductive System Disease 1.22E-03-3.39E-02 CLN3, PPP2R5C, PPP1R8, CDK6, CASK, NCOA3, PPP1R3D, CDKN1A, IL1B, RXRA, WNT1, PSEN1, RBBP4 PRPF19, VPRBP, PBX1, FBXW7, PDPK1, DICER1, SACM1L, ADH5 (includes EG:128), CD274, GNA13, HIPK1, HIPK2, KLF2, C4B, CDC25A, EWSR1, MED1, CREBBP, CDK6, NPHS2, UBD, RAG1, WASF2, RXRA, C3AR1, LDB3, SERPINA6, Organismal Survival 1.53E-03-2.42E-03 P2RX1, FKBP1A, UGCG, GABRB3, MYF6, BMPR1A, PTPN1, IGF1R, HGS, NFE2L2, RAD23B, CALR, TNFSF11, BGN, IGF2R, PLG, TPM3, CDKN1A, RBPJ, IL1B, RYK, MYBPC3, PSEN1

UPK3A, FBRSL1, IDS, ADCY4, RABGAP1L, CREB5, SECISBP2, EGFL8, JPH2, CAV1, AMMECR1, GNA13, HIPK2, TSHZ2, KCNQ5, ZCCHC4, ARHGAP27, MED1, TNFRSF10B, SUSD4, LARP4, DCTD, NPHS2, CNTN2, GSTCD, HSPA8, CCL4, RUNX1T1, C18ORF45, WASF2, TBC1D5, RXRA, C20ORF43, MAGI3, TSNARE1, EIF2S3, EIF4EBP2, THADA, FAM63B, CSMD2, C8ORF37, C1R, C9ORF86, HOXA5, ALX4, RBM19, VPS13B, NFE2L2, TNFSF11, GRB2, TDRD10, SLC6A19, TK2, IGF2R, MED27, ZNF284, RNF216, SEMA3A, HP, CAP2, ZNF136, CDKN1A, TMEM49, PLEKHA1, MEGF11, PSEN1, RYK, NAV2 (includes EG:89797), SLCO5A1, NLRP1, PDPK1, GEMIN5 (includes EG:25929), GGA2, TGFBR2, GPR4, TMTC2, ARHGAP20, COL11A2, SCN5A, ELN, PFKFB3, EWSR1, MDN1 (includes EG:23195), KDM2B, SLC12A7, ORMDL3, STX1A, NCOA3, TAF1, CPNE5, RAPH1, RAG1, ZNF184, MAPKBP1, LRRC38, SCD, KCNN4, HAUS6, CRLF2, KCNK3, LOC286467, ERC1, EIF2S1, SLC39A14, FARSB, GABRB2, HTR2C, SUCLA2, MRPS6 (includes EG:64968), BMPR1A, ZNF24 (includes EG:7572), CNTNAP5 (includes EG:129684), HS6ST2, SLC16A12, LRRC8A, Genetic Disorder 2.21E-03-3.39E-02 MMP19, SLC20A1, SLC25A13, NLRP3, PILRB (includes EG:29990), LMO7, PLA2G1B, SNX27, IGHA2, PDK3, BRD3, HNRNPCL1, PLG, GPR56, BBX, WNT10A, LAMA4, PGM2L1, IL10RB, SLC19A2, HADH, MYBPC3, GPR115, CENPF, NRL, C15ORF27, SLC25A26, DDX25, ATP8A1 (includes EG:10396), OFD1, MYLK2, DLG2, ROM1, RTF1, EXPH5, ZNF614, FANCB, GNB4, INTS7, KCNIP2, PTPRO, PXK, SERPINB7, ANKRD29, IRS2, CD274, HIPK1, CASP10, C4B, NBEAL1, DDX31, MITF, CREBBP, RALB, FAM126B, FAM83H, CACNA1C, NDST4, DONSON, UBD, WFDC5, EPB42, CAPN1, IL10RA, ZNF311, FOXE1, C3AR1, PRICKLE1, SPTBN1, LDB3, BATF, DUSP6, WASF3, ZNF143, FKBP1A, TNFSF10, RUVBL1, MRPL30, ODZ3, KRTAP2-4, MYO1B, AMD1, MYF6, ADAMTS19, IGF1R, KIAA0391, NSMCE1, HGS, ALOX15, CLN3, ACOX1, TYR, FETUB, PFN2, FAIM2, PRELID2, MARCH6, YLPM1, RAD54B, TRPM7, CTNNBL1, ZNF714, TRAPPC2, SORBS2, CDC42SE2, ADAMTSL1, RUFY3, NTSR1, AFAP1L1, ARHGAP26, CLN8, VPRBP, PRMT3, PBX1, FBXW7, PCCB, C1ORF175, PCMTD1, ZNF609, DICER1, IL8RA, WNT9A, ZC3H11A, SACM1L, USP7, ZSWIM5, LOC389634, GRIN2C, TNNT3, CDC25A, AIM1 (includes EG:202), SCD, KCNK3, MYLK2, DLG2, P2RX1, PDPK1, ROM1, GABRB2, HTR2C, KCNN1, GRIN2C, PTPN1, CAV1, IGF1R, KISS1, AMBN, GNA13, NFE2L2, Cell-To-Cell Signaling and Interaction 2.38E-03-3.39E-02 KCNQ5, SEMA3E, ALOX15, CLN3, GLS, CACNA1C, SLC1A1, STX1A, VDAC3, PLG, SEMA3A, TPM3, CAPN1, GAD1, CDKN1A, IL1B, CTNND1, RBBP4, MYBPC3, NTSR1 ATP8A1 (includes EG:10396), ADCY4, MYLK2, DLG2, CREB5, PTPRO, KCNIP2, PXK, CAV1, JPH2, ANKRD29, IRS2, KCNQ5, NBEAL1, MITF, TNFRSF10B, CACNA1C, WFDC5, CCL4, CAPN1, RXRA, PRICKLE1, CD34, WNT1, TMEM188, TSNARE1, MAGI3, SPTBN1, ADAM17, DUSP6, BATF, THADA, WASF3, TNFSF10, FKBP1A, CSMD2, ODZ3, ADAMTS19, IGF1R, NSMCE1, ALOX15, GRB2, TYR, ACOX1, PRELID2, MARCH6, IGF2R, MED27, RNF216, SEMA3A, TRPM7, CTNNBL1, CDKN1A, SORBS2, ADAMTSL1, MEGF11, PSEN1, NAV2 Cardiovascular Disease 2.45E-03-3.39E-02 (includes EG:89797), ARHGAP26, PBX1, PDPK1, C1ORF175, DICER1, ZC3H11A, TGFBR2, GRIN2C, ASXL2, ARHGAP20, KLF2, SCN5A, CDC25A, AIM1 (includes EG:202), ELN, SSTR4, SLC4A7, SLC12A7, SLC1A1, RAPH1, RAG1, FLJ22536, ERC2, MAPKBP1, SCD, KCNN4, HAUS6, KCNK3, ITM2B, APOC2, ZNF529, ZBTB38, GABRB2, GABRB3, MRPS6 (includes EG:64968), CNTNAP5 (includes EG:129684), NCALD, FMO1, SLC16A12, FAF2, PPP1R9A, CALR, NLRP3, BRD3, PLG, SIRPB2, BBX, LAMA4, OTUB1, IL1B, EDNRA, MYBPC3, RIN2

SPTBN1, BARHL1, KCNK3, AKTIP, MYLK2, P2RX1, DLG2, UGCG, PDPK1, ROM1, GABRB2, TGFBR2, HTR2C, KCNN1, GABRB3, KCNIP2, GRIN2C, IGF1R, Nervous System Development and Function 2.49E-03-3.39E-02 KISS1, IRS2, SEMA3E, BBS4, KCNQ5, SMN2, CLN3, MED1, POU4F1, GLS, RALB, PFN2, CACNA1C, SLC1A1, DLX2, VDAC3, STX1A, CNTN2, SEMA3A, GPR56, PIP5K1A, LAMA4, GAD1, CDKN1A, IL1B, RXRA, WNT1, NTSR1, PSEN1 ADAM17, GSTP1, NLRP3, MITF, TYR, NFKBIZ, SERPINB2, PLG, CCL4, Dermatological Diseases and Conditions 2.65E-03-3.39E-02 CDKN1A, CAV1, RAG1, EDNRA, IL1B, EIF2AK2, RXRA, CD34, WNT1, C4B, PSEN1, MMP19 Endocrine System Development and Function 2.79E-03-2.8E-02 PLG, PTPN1, CDKN1A, IGF1R, KISS1, IL1B, ERC1, IRS2, NFE2L2 SPTBN1, ADAM17, PRPF19, AKTIP, PRMT3, FKBP1A, PDPK1, FBXW7, APOC2, ERC1, TGFBR2, PTPRO, IL34, IGF1R, SMG1, CALR, PRMT2, CREBBP, CDK6, Post-Translational Modification 3.07E-03-3.39E-02 CNTN2, HSPA8, PRMT7, WHSC1L1, CCL4, TRPM7, TAF1, B4GALT1, CAPN1, GAD1, IL1B, ULBP2, EDNRA, IDO1, UHMK1, EIF2AK2, CD34, PSEN1 C15ORF27, NAV2 (includes EG:89797), GSTP1, SLCO5A1, DDX25, PLK3, CSNK1A1, PBX1, DLG2, PCMTD1, WNT9A, CREB5, TGFBR2, ZNF614, USP7, INTS7, ZSWIM5, TMTC2, LOC389634, ARHGAP20, JPH2, SERPINB7, CD274, HIPK2, CDC25A, SOX4, SSTR4, NBEAL1, MED1, POLE2, MOAP1, TNFRSF10B, CREBBP, CDK6, SLC4A7, CACNA1C, DDX17, UBD, GAD1, PUS10, IDO1, Gastrointestinal Disease 3.19E-03-3.39E-02 ZNF311, RXRA, FLJ22536, WNT1, MAGI3, ERC2, TMTC3, THADA, BATF, FIBP, TNFSF10, ODZ3, MLL3, MYF6, CNTNAP5 (includes EG:129684), HOXA5, PTPN1, IGF1R, RBM19, WSB2, ASAP3, SULF2, NFE2L2, SEMA3E, CALR, ALOX15, CLN3, NLRP3, LMO7, GRB2, BGN, FETUB, PRELID2, TDRD10, FAIM2, IGF2R, FDXR, PLG, DIP2C, LAMA4, NT5E, CDKN1A, IL10RB, IL1B, CDC42SE2, ADAMTSL1, CTNND1 BBS4, CENPF, SMN2, NRL, TNFSF11, ADAM17, EWSR1, MITF, GRB2, KDM2B, Cellular Development 3.36E-03-3.39E-02 CDK6, PBX1, TNFSF10, PDPK1, DICER1, RUNX1T1, CDKN1A, CAV1, IL10RA, IGF1R, IL1B, IRS2, HIPK2, RXRA Hematological System Development and CENPF, TNFSF11, ADAM17, MED1, PBX1, CDK6, TNFSF10, PDPK1, TGFBR2, 3.36E-03-3.39E-02 Function CCL4, RUNX1T1, LAMA4, PTPN1, CDKN1A, IGF1R, IL10RA, IRS2, NFE2L2 SCD, GSTP1, ADAM17, SLC25A13, NLRP3, EWSR1, ATF5, MED1, ACOX1, Hepatic System Disease 3.36E-03-3.39E-02 TNFSF10, TGFBR2, NT5E, CDKN1A, PTPN1, RAG1, IRS2, RXRA, NFE2L2 MYLK2, PBX1, TNFSF10, FKBP1A, DICER1, WNT9A, ELAVL1, TGFBR2, MYF6, BMPR1A, HOXA5, CAV1, IGF1R, ALX4, SULF2, COL11A2, KLF2, CALR, Skeletal and Muscular System Development 3.36E-03-3.39E-02 ALOX15, TNFSF11, GRB2, MED1, POU4F1, TNFRSF10B, CREBBP, PLG, NOV, and Function TPM3, LAMA4, CAPN1, CDKN1A, RBPJ, IL1B, IFT52, EIF2AK2, RXRA, WNT1, MYBPC3, RYK, PSEN1 CENPF, AFAP1L1, NAV2 (includes EG:89797), DDX25, ARHGAP26, VPRBP, DLG2, NLRP1, RABGAP1L, CREB5, RTF1, SACM1L, TGFBR2, GRIN2C, TMTC2, JPH2, TSHZ2, SCN5A, AIM1 (includes EG:202), G3BP2, ZCCHC4, SSTR4, DDX31, POLE2, MITF, RALB, CDK6, CACNA1C, SUSD4, SLC1A1, STX1A, ATP6V1A, Psychological Disorders 3.74E-03-1.65E-02 GSTCD, GAD1, IL10RA, UHMK1, C18ORF45, RXRA, DUSP6, CDH23, ODZ3, GABRB2, HTR2C, GABRB3, PTPN1, CNTNAP5 (includes EG:129684), RBM19, SEMA3E, CALR, LRRC2, LMO7, PPP2R5C, TYR, PFN2, PLA2G1B, SNX27, ZNF284, HNRNPCL1, RNF216, SEMA3A, HP, CAP2, BBX, DIP2C, B4GALT1, IL1B, SORBS2, MEGF11, ATP6V1B2, RIN2

Digestive System Development and Function 4.92E-03-3.39E-02 TGFBR2, MED1, BMPR1A, ACOX1, GAD1, ALX4, C3AR1, ONECUT1 C15ORF27, SLC25A26, ATP8A1 (includes EG:10396), DDX25, MYLK2, DLG2, CREB5, EGFL8, PTPRO, PXK, JPH2, CD274, GNA13, HIPK1, C4B, TSHZ2, CASP10, KCNQ5, ZCCHC4, DDX31, ARHGAP27, RALB, FAM126B, TNFRSF10B, CACNA1C, DCTD, CNTN2, HSPA8, RUNX1T1, CCL4, IL10RA, ZNF311, PRICKLE1, C3AR1, C20ORF43, MAGI3, THADA, FAM63B, WASF3, ZNF143, TNFSF10, MRPL30, CSMD2, ODZ3, KRTAP2-4, C1R, IGF1R, ALX4, KIAA0391, NFE2L2, TNFSF11, TYR, TDRD10, HP, TRPM7, CAP2, ZNF714, CDKN1A, SORBS2, ADAMTSL1, PLEKHA1, PSEN1, NAV2 (includes EG:89797), SLCO5A1, Immunological Disease 4.99E-03-3.39E-02 CLN8, PRMT3, NLRP1, PBX1, PDPK1, FBXW7, GEMIN5 (includes EG:25929), ZNF609, DICER1, IL8RA, WNT9A, SACM1L, TGFBR2, USP7, ZSWIM5, ARHGAP20, COL11A2, KLF2, PFKFB3, EWSR1, CDK6, LOC387761, NCOA3, VRK3, RAG1, IDO1, ZNF184, FLJ22536, ERC2, AKTIP, CDH23, ZNF429, PPP1CB, ERC1, SLC39A14, GABRB2, TRA2A, HTR2C, GABRB3, MRPS6 (includes EG:64968), KIAA0247, WSB2, LRRC8A, PPP1R9A, CALR, SLC25A13, PILRB (includes EG:29990), LRRC2, LMO7, BGN, NFKBIZ, DIP2C, B4GALT1, WNT10A, IL10RB, EDNRA, IL1B, EIF2AK2, SLC9A8, MYBPC3

SLC25A26, C15ORF27, NAV2 (includes EG:89797), DDX25, SLCO5A1, ATP8A1 (includes EG:10396), VPRBP, PRMT3, DLG2, PBX1, GEMIN5 (includes EG:25929), ZNF609, IL8RA, CREB5, WNT9A, SERPINB2, SACM1L, USP7, EGFL8, PXK, JPH2, IRS2, AMBN, CD274, COL11A2, KLF2, C4B, CASP10, KCNQ5, ZCCHC4, DDX31, TNFRSF10B, RALB, CDK6, CACNA1C, DCTD, NCOA3, LOC387761, Connective Tissue Disorders 5.2E-03-3.39E-02 UBD, HSPA8, CCL4, RAPH1, IL10RA, C3AR1, PRICKLE1, C20ORF43, MAGI3, FAM63B, ZNF143, ZNF429, CDH23, PPP1CB, TNFSF10, ERC1, CSMD2, ODZ3, SLC39A14, KRTAP2-4, GABRB2, C1R, GABRB3, MRPS6 (includes EG:64968), ADAMTS19, KIAA0247, PTPN1, IGF1R, ALX4, KIAA0391, WSB2, MMP19, PPP1R9A, TNFSF11, NLRP3, LRRC2, PRMT2, BGN, TDRD10, IGF2R, PLG, HP, WNT10A, ZNF714, DIP2C, B4GALT1, TRAPPC2, CDKN1A, IL1B, EDNRA, SORBS2 ADAMTSL1 EIF2AK2 SLC9A8 PSEN1 MX2, POLD3, CCL4, EIF4EBP2, PPP1R8, IL10RA, IL1B, TNFSF10, RAG1, Infection Mechanism 6.49E-03-2.8E-02 EIF2AK2, DICER1, RXRA TBC1D3F, CALR, GSTP1, VPRBP, POLE2, MED1, TYR, PLA2G1B, RFC1, DNA Replication, Recombination, and Repair 6.5E-03-3.39E-02 DICER1, POLD3, RUNX1T1, NT5E, CDKN1A, IGF1R, TMEM49, CAV1, IL1B, RBPJ, SMG1, EIF2AK2, CDC25A MFNG, PDPK1, PPP1CB, SACM1L, TGFBR2, B4GALT1, PTPN1, CAV1, IGF1R, Carbohydrate Metabolism 6.57E-03-3.39E-02 IL1B, IRS2, SLC35B4, PSEN1 SEMA3E, PDPK1, TNFSF10, IL8RA, IGF2R, PLG, TGFBR2, SEMA3A, ESAM, Cellular Movement 6.57E-03-3.39E-02 CAPN1, CAV1, IL1B, NFE2L2 ALOX15, NLRP3, AKTIP, TYR, TNFRSF10B, FBXW7, PDPK1, TNFSF10, Hematological Disease 6.57E-03-3.39E-02 DICER1, SERPINB2, PLG, TGFBR2, FANCB, CCL4, CDKN1A, IGF1R, IDO1, IL1B, CD274, KLF2, NFE2L2, PSEN1, TPMT Immune Cell Trafficking 6.57E-03-3.39E-02 IL1B, NFE2L2 SLC25A26, C15ORF27, ATP8A1 (includes EG:10396), DDX25, DLG2, CREB5, SERPINB2, ZNF614, INTS7, EGFL8, PXK, JPH2, SERPINB7, CD274, CASP10, C4B, KCNQ5, ZCCHC4, DDX31, NBEAL1, MED1, TNFRSF10B, CREBBP, RALB, CACNA1C, DCTD, HSPA8, CCL4, IL10RA, ZNF311, RXRA, PRICKLE1, C3AR1, C20ORF43, MAGI3, BATF, FAM63B, THADA, ZNF143, TNFSF10, CSMD2, ODZ3, KRTAP2-4, C1R, MYF6, IGF1R, ALX4, RBM19, KIAA0391, NFE2L2, TNFSF11, GRB2, ACOX1, FETUB, PRELID2, TDRD10, FAIM2, HP, ZNF714, CDKN1A, SORBS2, CDC42SE2, ADAMTSL1, PSEN1, NAV2 (includes EG:89797), SLCO5A1, Inflammatory Disease 6.57E-03-3.39E-02 PRMT3, PBX1, GEMIN5 (includes EG:25929), PCMTD1, ZNF609, IL8RA, WNT9A, SACM1L, TGFBR2, USP7, ZSWIM5, GRIN2C, LOC389634, TMTC2, ARHGAP20, COL11A2, SCN5A, SSTR4, EWSR1, POLE2, CDK6, SLC4A7, SLC1A1, ORMDL3, LOC387761, NCOA3, PUS10, RAPH1, RAG1, IDO1, FLJ22536, ERC2, TMTC3, CRLF2, FIBP, CDH23, ZNF429, PPP1CB, ERC1, SLC39A14, GABRB2, HTR2C, GABRB3, MRPS6 (includes EG:64968), KIAA0247, CNTNAP5 (includes EG:129684), WSB2, SULF2, ASAP3, SEMA3E, PPP1R9A, NLRP3, LRRC2, LMO7, BGN, NFKBIZ, PLG, WNT10A, DIP2C, B4GALT1, IL10RB, IL1B, EDNRA, EIF2AK2, SLC9A8, RIN2, MYBPC3 Inflammatory Response 6.57E-03-3.39E-02 CCL4, CAV1, IL1B, NFE2L2 Nucleic Acid Metabolism 6.57E-03-3.39E-02 SCD, B4GALT1, NT5E, ACOX1, DCTD, SLC35B4, TPMT Tumor Morphology 6.76E-03-3.39E-02 TGFBR2, PLG, CAV1, KISS1, CD274 SLC25A26, C15ORF27, NAV2 (includes EG:89797), DDX25, SLCO5A1, ATP8A1 (includes EG:10396), PRMT3, DLG2, PBX1, GEMIN5 (includes EG:25929), ZNF609, IL8RA, CREB5, WNT9A, SACM1L, USP7, EGFL8, PXK, CAV1, JPH2, CD274, COL11A2, CDC25A, C4B, CASP10, KCNQ5, ZCCHC4, EWSR1, DDX31, NPAT, TNFRSF10B, RALB, CDK6, CACNA1C, DCTD, NCOA3, LOC387761, HSPA8, TAF1, CCL4, CAPN1, RAPH1, IL10RA, RBBP6 (includes EG:5930), PRICKLE1, Skeletal and Muscular Disorders 7.25E-03-3.39E-02 C3AR1, C20ORF43, MAGI3, FAM63B, ZNF143, ZNF429, CDH23, PPP1CB, TNFSF10, ERC1, CSMD2, ODZ3, SLC39A14, KRTAP2-4, GABRB2, C1R, GABRB3, MRPS6 (includes EG:64968), KIAA0247, IGF1R, LAMP1, ALX4, OAZ1, KIAA0391, WSB2, PPP1R9A, TNFSF11, NLRP3, LRRC2, BGN, TDRD10, RPL23, PLG, HP, TRPM7, WNT10A, ZNF714, DIP2C, B4GALT1, LAMA4, CDKN1A, XAF1, EEF1A1, IL1B, EDNRA, SORBS2, ADAMTSL1, SLC9A8, PSEN1

TGFBR2, PLG, CALR, ALOX15, NLRP3, B4GALT1, NT5E, CDKN1A, CAV1, Organismal Injury and Abnormalities 7.78E-03-3.39E-02 LAMP1, PSEN1 BBS4, CALR, MED1, BGN, ACOX1, CAV1, KISS1, IRS2, DICER1, RXRA, Organ Morphology 8.57E-03-3.39E-02 C3AR1, PSEN1 Protein Trafficking 1.07E-02-1.07E-02 SNX27, HGS OFD1, PBX1, FKBP1A, PDPK1, GABRB2, TGFBR2, HTR2C, FANCB, GABRB3, HOXA5, CAV1, IGF1R, ALX4, VPS13B, GNA13, HIPK2, HIPK1, SCN5A, MMP19, Developmental Disorder 1.4E-02-3.39E-02 BBS4, ALOX15, ELN, SSTR4, TNFSF11, MITF, MED1, GRB2, TYR, CREBBP, CACNA1C, PLG, GPR56, TPM3, TRAPPC2, LAMA4, GAD1, CDKN1A, IL1B, EDNRA, RBPJ, RXRA, PSEN1, RYK, MYBPC3 CENPF, ADAM17, TNFSF11, MED1, PBX1, CDK6, PDPK1, TGFBR2, RUNX1T1, Hematopoiesis 1.43E-02-3.39E-02 CCL4, CDKN1A, PTPN1, IGF1R, IL10RA, IRS2 Cell Signaling 2.15E-02-2.45E-02 IL10RA, IL10RB, IFT52, HIPK2, HIPK1, WNT9A ADH5 (includes EG:128), PLG, FKBP1A, FOLR2, CACNA1C, IL1B, GABRB2, Drug Metabolism 2.15E-02-3.39E-02 TPMT Visual System Development and Function 2.15E-02-3.39E-02 BBS4, NRL, CLN8, MED1, CDH23 Vitamin and Mineral Metabolism 2.15E-02-3.39E-02 ADH5 (includes EG:128), FOLR2 BBS4, SPTBN1, BARHL1, MED1, AKTIP, PDPK1, DLX2, TGFBR2, GPR56, Organ Development 2.33E-02-3.39E-02 BMPR1A, CAV1, IGF1R, IRS2, WNT1, PSEN1 Endocrine System Disorders 2.8E-02-2.8E-02 GNA13, ACVR1C Protein Folding 2.8E-02-2.8E-02 HSPA8, FKBP1A Antigen Presentation 3.39E-02-3.39E-02 NFE2L2 Behavior 3.39E-02-3.39E-02 GABRB3, GPSM1 Cell-mediated Immune Response 3.39E-02-3.39E-02 CDKN1A Hair and Skin Development and Function 3.39E-02-3.39E-02 BMPR1A, CAV1 Humoral Immune Response 3.39E-02-3.39E-02 ADAM17 Metabolic Disease 3.39E-02-3.39E-02 SLC1A1 Renal and Urological Disease 3.39E-02-3.39E-02 CAV1 Renal and Urological System Development and 3.39E-02-3.39E-02 BGN Function Respiratory System Development and Function 3.39E-02-3.39E-02 DICER1