NATURE August 27, 1960 VOL. 187 OBITUARY
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Peter P. T. Sah and the Synthesis of Vitamin C in China and Europe
EASTM 20 (2003 ): 92-98 Peter P. T. Sah and the Synthesis of Vitamin C in China and Europe Zhang Li [Zhang Li is Associate Professor at the Institute for the History of Natural Sci ence, Chinese Academy of Sciences. She has published a number of articles on the history of modern chemistry of both the West and China and the social his tory of science in twentieth-century China, including studies on the influence of higher education reform on chemical education in the 1950s in China (1992) and the coordination between national needs and scientists' autonomy during 1949-/965 (2003). She recently received her doctoral degree in the Philosophy of Science from Peking University, completing a dissertation on the institution alization of science in the People's Republic of China. Her forthcoming book is called Gaofenzi kexue zai Zhongguo de jianli ( 1949-1965) r%'J 5t r f-4 ~ ft i:p 00 R"J ~ JI. (1949-1965) ( Institutionalization of Polymer Science in China(l949- /965) Jinan: Shandong jiaoyu chubanshe 2003, ¥ff 1¥i : W J'.f: ¥!I.. W tB It& ffr±, 2003).J * * * The synthesis of vitamin C was one of the main scientific achievements in the 1930s. Many scientists in Europe made contributions to this field, especially Albert Szent-Gyorgyi (1893-1986) from Hungary and Sir Walter Norman Ha worth ( 1883-1950) from England, both of whom won the Nobel Prize in 1937. In the same period, a Chinese chemist, Sa Bentie ~ :;$: ~ (1900-1986), better known outside China as Peter P. T. Sah, was also studying vitamin C. -
Curriculum Vitae Prof. Dr. Adolf Otto Reinhold Windaus
Curriculum Vitae Prof. Dr. Adolf Otto Reinhold Windaus Name: Adolf Otto Reinhold Windaus Lebensdaten: 25. Dezember 1876 - 9. Juni 1956 Adolf Windaus war ein deutscher Chemiker. Er untersuchte Naturstoffe, vor allem die biochemisch wichtigen Sterine und ihren Zusammenhang mit anderen Naturstoffen. Er entdeckte die chemische Verwandtschaft von Cholesterin und Gallensäure. Außerdem lieferte er Arbeiten über Vitamine, vor allem das Vitamin D. Zwischen 1927 und 1931 gelang ihm die Isolierung mehrerer D-Vitamine. Seine Forschungen bildeten die Grundlage für später von seinen Schülern durchgeführten Arbeiten über die menschlichen Sexualhormone. Für seine Verdienste um die Erforschung des Aufbaus der Sterine und ihres Zusammenhangs mit den Vitaminen wurde Adolf Windaus 1928 mit dem Nobelpreis für Chemie ausgezeichnet. Akademischer und beruflicher Werdegang Adolf Windaus begann 1895 ein Studium der Medizin an der Universität Freiburg. Er wechselte nach Berlin, wo er 1897 das Physikum bestand. 1899 wurde er in Freiburg mit einer Arbeit über Neue Beiträge zur Kenntnis der Digitalisstoffe promoviert wurde. 1901 war er zunächst in Berlin als Assistent von Emil Fischer (Nobelpreis für Chemie 1902) tätig. Während dieser Zeit wandte er sich zunehmend chemischen Fragestellungen zu. Außerdem begann er mit seinen Forschungen zu den Sterinen. 1903 habilitierte er sich in Freiburg mit einer Arbeit über Cholesterin. 1906 erhielt er eine außerordentliche Professur an der Universität Göttingen. Im Anschluss wechselte er für zwei Jahre an die Universität Innsbruck, wo er eine außerordentliche Professur für angewandte medizinische Chemie erhielt. 1915 ging er zurück nach Göttingen, wo er als Nachfolger von Otto Wallach (Nobelpreis für Chemie 1910) Ordinarius für Chemie wurde. Dort blieb er bis zu seiner Emeritierung im Jahr 1944. -
Peptide Chemistry up to Its Present State
Appendix In this Appendix biographical sketches are compiled of many scientists who have made notable contributions to the development of peptide chemistry up to its present state. We have tried to consider names mainly connected with important events during the earlier periods of peptide history, but could not include all authors mentioned in the text of this book. This is particularly true for the more recent decades when the number of peptide chemists and biologists increased to such an extent that their enumeration would have gone beyond the scope of this Appendix. 250 Appendix Plate 8. Emil Abderhalden (1877-1950), Photo Plate 9. S. Akabori Leopoldina, Halle J Plate 10. Ernst Bayer Plate 11. Karel Blaha (1926-1988) Appendix 251 Plate 12. Max Brenner Plate 13. Hans Brockmann (1903-1988) Plate 14. Victor Bruckner (1900- 1980) Plate 15. Pehr V. Edman (1916- 1977) 252 Appendix Plate 16. Lyman C. Craig (1906-1974) Plate 17. Vittorio Erspamer Plate 18. Joseph S. Fruton, Biochemist and Historian Appendix 253 Plate 19. Rolf Geiger (1923-1988) Plate 20. Wolfgang Konig Plate 21. Dorothy Hodgkins Plate. 22. Franz Hofmeister (1850-1922), (Fischer, biograph. Lexikon) 254 Appendix Plate 23. The picture shows the late Professor 1.E. Jorpes (r.j and Professor V. Mutt during their favorite pastime in the archipelago on the Baltic near Stockholm Plate 24. Ephraim Katchalski (Katzir) Plate 25. Abraham Patchornik Appendix 255 Plate 26. P.G. Katsoyannis Plate 27. George W. Kenner (1922-1978) Plate 28. Edger Lederer (1908- 1988) Plate 29. Hennann Leuchs (1879-1945) 256 Appendix Plate 30. Choh Hao Li (1913-1987) Plate 31. -
Bibliography Physics and Human Rights Michele Irwin and Juan C Gallardo August 18, 2017
Bibliography Physics and Human Rights Michele Irwin and Juan C Gallardo August 18, 2017 Physicists have been actively involved in the defense of Human Rights of colleague physicists, and scientists in general, around the world for a long time. What follows is a list of talks, articles and informed remembrances on Physics and Human Rights by physicist-activists that are available online. The selection is not exhaustive, on the contrary it just reflects our personal knowledge of recent publications; nevertheless, they are in our view representative of the indefatigable work of a large number of scientists affirming Human Rights and in defense of persecuted, in prison or at risk colleagues throughout the world. • “Ideas and Opinions” Albert Einstein Crown Publishers, 1954, 1982 The most definitive collection of Albert Einstein's writings, gathered under the supervision of Einstein himself. The selections range from his earliest days as a theoretical physicist to his death in 1955; from such subjects as relativity, nuclear war or peace, and religion and science, to human rights, economics, and government. • “Physics and Human Rights: Reflections on the past and the present” Joel L. Lebowitz Physikalische Blatter, Vol 56, issue 7-8, pages 51-54, July/August 2000 http://onlinelibrary.wiley.com/doi/10.1002/phbl.20000560712/pdf Based loosely on the Max von Laue lecture given at the German Physical Society's annual meeting in Dresden, 03/2000. This article focus on the moral and social responsibilities of scientists then -Nazi period in Germany- and now. Max von Laue's principled moral response at the time, distinguished him from many of his contemporary scientists. -
A Nobel Synthesis
MILESTONES IN CHEMISTRY Ian Grayson A nobel synthesis IAN GRAYSON Evonik Degussa GmbH, Rodenbacher Chaussee 4, Hanau-Wolfgang, 63457, Germany he first Nobel Prize for chemistry was because it is a scientific challenge, as he awarded in 1901 (to Jacobus van’t Hoff). described in his Nobel lecture: “The synthesis T Up to 2010, the chemistry prize has been of brazilin would have no industrial value; awarded 102 times, to 160 laureates, of whom its biological importance is problematical, only four have been women (1). The most but it is worth while to attempt it for the prominent area for awarding the Nobel Prize sufficient reason that we have no idea how for chemistry has been in organic chemistry, in to accomplish the task” (4). which the Nobel committee includes natural Continuing the list of Nobel Laureates in products, synthesis, catalysis, and polymers. organic synthesis we arrive next at R. B. This amounts to 24 of the prizes. Reading the Woodward. Considered by many the greatest achievements of the earlier organic chemists organic chemist of the 20th century, he who were recipients of the prize, we see that devised syntheses of numerous natural they were drawn to synthesis by the structural Alfred Nobel, 1833-1896 products, including lysergic acid, quinine, analysis and characterisation of natural cortisone and strychnine (Figure 1). 6 compounds. In order to prove the structure conclusively, some In collaboration with Albert Eschenmoser, he achieved the synthesis, even if only a partial synthesis, had to be attempted. It is synthesis of vitamin B12, a mammoth task involving nearly 100 impressive to read of some of the structures which were deduced students and post-docs over many years. -
Liste Der Nobelpreisträger
Physiologie Wirtschafts- Jahr Physik Chemie oder Literatur Frieden wissenschaften Medizin Wilhelm Henry Dunant Jacobus H. Emil von Sully 1901 Conrad — van ’t Hoff Behring Prudhomme Röntgen Frédéric Passy Hendrik Antoon Theodor Élie Ducommun 1902 Emil Fischer Ronald Ross — Lorentz Mommsen Pieter Zeeman Albert Gobat Henri Becquerel Svante Niels Ryberg Bjørnstjerne 1903 William Randal Cremer — Pierre Curie Arrhenius Finsen Bjørnson Marie Curie Frédéric John William William Mistral 1904 Iwan Pawlow Institut de Droit international — Strutt Ramsay José Echegaray Adolf von Henryk 1905 Philipp Lenard Robert Koch Bertha von Suttner — Baeyer Sienkiewicz Camillo Golgi Joseph John Giosuè 1906 Henri Moissan Theodore Roosevelt — Thomson Santiago Carducci Ramón y Cajal Albert A. Alphonse Rudyard \Ernesto Teodoro Moneta 1907 Eduard Buchner — Michelson Laveran Kipling Louis Renault Ilja Gabriel Ernest Rudolf Klas Pontus Arnoldson 1908 Metschnikow — Lippmann Rutherford Eucken Paul Ehrlich Fredrik Bajer Theodor Auguste Beernaert Guglielmo Wilhelm Kocher Selma 1909 — Marconi Ostwald Ferdinand Lagerlöf Paul Henri d’Estournelles de Braun Constant Johannes Albrecht Ständiges Internationales 1910 Diderik van Otto Wallach Paul Heyse — Kossel Friedensbüro der Waals Allvar Maurice Tobias Asser 1911 Wilhelm Wien Marie Curie — Gullstrand Maeterlinck Alfred Fried Victor Grignard Gerhart 1912 Gustaf Dalén Alexis Carrel Elihu Root — Paul Sabatier Hauptmann Heike Charles Rabindranath 1913 Kamerlingh Alfred Werner Henri La Fontaine — Robert Richet Tagore Onnes Theodore -
On the Planck-Einstein Relation Peter L
On the Planck-Einstein Relation Peter L. Ward US Geological Survey retired Science Is Never Settled PO Box 4875, Jackson, WY 83001 [email protected] Abstract The Planck-Einstein relation (E=hν), a formula integral to quantum mechanics, says that a quantum of energy (E), commonly thought of as a photon, is equal to the Planck constant (h) times a frequency of oscillation of an atomic oscillator (ν, the Greek letter nu). Yet frequency is not quantized—frequency of electromagnetic radiation is well known in Nature to be a continuum extending over at least 18 orders of magnitude from extremely low frequency (low-energy) radio signals to extremely high-frequency (high-energy) gamma rays. Therefore, electromagnetic energy (E), which simply equals a scaling constant times a continuum, must also be a continuum. We must conclude, therefore, that electromagnetic energy is not quantized at the microscopic level as widely assumed. Secondly, it makes no physical sense in Nature to add frequencies of electromagnetic radiation together in air or space—red light plus blue light does not equal ultraviolet light. Therefore, if E=hν, then it makes no physical sense to add together electromagnetic energies that are commonly thought of as photons. The purpose of this paper is to look at the history of E=hν and to examine the implications of accepting E=hν as a valid description of physical reality. Recognizing the role of E=hν makes the fundamental physics studied by quantum mechanics both physically intuitive and deterministic. Introduction On Sunday, October 7, 1900, Heinrich Rubens and wife visited Max Planck and wife for afternoon tea (Hoffmann, 2001). -
Heisenberg and the Nazi Atomic Bomb Project, 1939-1945: a Study in German Culture
Heisenberg and the Nazi Atomic Bomb Project http://content.cdlib.org/xtf/view?docId=ft838nb56t&chunk.id=0&doc.v... Preferred Citation: Rose, Paul Lawrence. Heisenberg and the Nazi Atomic Bomb Project, 1939-1945: A Study in German Culture. Berkeley: University of California Press, c1998 1998. http://ark.cdlib.org/ark:/13030/ft838nb56t/ Heisenberg and the Nazi Atomic Bomb Project A Study in German Culture Paul Lawrence Rose UNIVERSITY OF CALIFORNIA PRESS Berkeley · Los Angeles · Oxford © 1998 The Regents of the University of California In affectionate memory of Brian Dalton (1924–1996), Scholar, gentleman, leader, friend And in honor of my father's 80th birthday Preferred Citation: Rose, Paul Lawrence. Heisenberg and the Nazi Atomic Bomb Project, 1939-1945: A Study in German Culture. Berkeley: University of California Press, c1998 1998. http://ark.cdlib.org/ark:/13030/ft838nb56t/ In affectionate memory of Brian Dalton (1924–1996), Scholar, gentleman, leader, friend And in honor of my father's 80th birthday ― ix ― ACKNOWLEDGMENTS For hospitality during various phases of work on this book I am grateful to Aryeh Dvoretzky, Director of the Institute of Advanced Studies of the Hebrew University of Jerusalem, whose invitation there allowed me to begin work on the book while on sabbatical leave from James Cook University of North Queensland, Australia, in 1983; and to those colleagues whose good offices made it possible for me to resume research on the subject while a visiting professor at York University and the University of Toronto, Canada, in 1990–92. Grants from the College of the Liberal Arts and the Institute for the Arts and Humanistic Studies of The Pennsylvania State University enabled me to complete the research and writing of the book. -
The Growth and Decline of German Scientific Publishing 1850–1945
A Century of Science Publishing E.H. Fredriksson (Ed.) IOS Press, Chapter The Growth and Decline of German Scientific Publishing – Heinz Sarkowski Historian of German Publishing, Germany Summary The development of commercial scientific publishing companies in Germany commenced in the middle of the th century. University and Academy publishers never had a chance. Scientific society publishers emerged only in / during inflation, but had little impact. German publishers dominated in particular in Mathematics, Physics and Chemistry. In , % of the articles covered by the Chemical Abstracts were from German publica- tions. Until the German language was the “lingua franca” of Europe’s sci- entific community. The export of German science publishers was significant, and in around % of Springer Verlag’s turnover came from export. The international significance of German science can be seen from the large number of Nobel Prizes bestowed on it: German scientists were recipients from to , from to . After many highly qualified scientists fled the Nazis and found refuge in the Western world, constituting the start of the decline of German science. During World War II German science literature was reprinted on a large scale and sold worldwide. After the War the German lan- guage had definitively lost its world significance and German companies con- centrated thereafter on production of textbooks and journals for the home mar- ket. In the sixties they also commenced publication of research literature in English. From until the First World War one third of all Nobel Prizes in the fields of physics, chemistry and medicine were awarded to German scientists. This doc- uments the immense significance of German science before the First World War. -
Pilgrimage Through the History of German Natural Science, University City Göttingen II Kaoru Harada Email:[email protected]
Pilgrimage through the History of German Natural Science, University City Göttingen II Kaoru Harada Email:[email protected] Scientists in the same generation as F. Wohlelr (Fig. 89-96). We have seen several pictures of scientists worked in the University of Göttingen. Additional portraits of chemist outside the University have also collected in the Museum. Some of the chemists are Jöns Jacob Berzelius (1779-1848, Fig. 89), Eilhardt Mitscherlich (1794-1863), (Fig. 90), Justus Leibig (1803-1873, Fig. 91), Michel Eugene Chevreul (1786-1889), (Fig. 92, 93), F. W. Sertürner (1783-1841), (Fig. 94) and Ernst Otto Beckmann (1853-1923), (Fig. 95, 96). J. J. Berzelius (Fig. 89) was a famous Swedish chemist. He contributed much to the development of modern chemistry on the following subjects : [Discovery of elements, nomenclature of Fig. 90 Photograph of Eilhardt Mitscherlich (1794-1863). elements, elemental signs, atomic weights of elements, allotrope, J. Liebig (Fig. 91) was a great German chemist, and his young concept of catalyst and isomer]. The accurate measurements of day’s life was dynamic. He was a self taught chemist and he atomic weight based on the R. Boyl’s atomic theory were his studied at Paris for two years and he polished up his chemistry. great contribution to chemistry in the first half of the 19th century. He made human relations with L. J. Gay-Lussac (1778-1850) and A. Humboldt (1769-1859) because of J. Libig’s (1803-1873) interest on Arsenal. He got a position at Giessen University in the age 21 by the recommendation of A. -
Hermann Emil Fischer: Life and Achievements
GENERAL ARTICLE Hermann Emil Fischer: Life and Achievements G Nagendrappa Emil Fischer, considered as one of the greatest chemists of all times, carried out much of the fundamental work on purines, sugars, proteins, stereochemistry and several other areas of chemistry during the late nineteenth and early twentieth century. Because most of these are biological molecules, he is known as the ‘Father of Biochemistry’. His achievements in G Nagendrappa was a Professor of Organic chemical synthesis and analytical skills were much ahead of Chemistry at Bangalore his times. He was the second to get the Nobel Prize in Chem- University, and Head of istry in 1902. the Department of Medicinal Chemistry, Sri Introduction Ramachandra (Medical) University, Chennai. He is Carbohydrates, proteins, fats, and nucleic acids are the four major currently in Jain Univer- sity, Bangalore. He chemical constituents of living organisms. These four classes of continues to teach and do organic compounds are the main players in the emergence and research. His work is in existence of life. Extensive pioneering contributions to the devel- the area of organosilicon opment of all these areas of organic chemistry and biochemistry chemistry, synthetic and mechanistic organic were made by Emil Fischer through his more than four decades of chemistry, and clay- brilliant research work starting from the early 1870s. His uncanny catalysed organic reactions skills in analytical and synthetic work, his extraordinary under- (Green Chemistry). standing of the enormous amount of experimental results and their correct interpretation laid a solid foundation for the chemis- try of these biologically important molecules. Though his work essentially constituted analytical and synthetic organic chemis- try, its reach extended to other areas, particularly stereochemis- try, biochemistry, physiology and medicine. -
Dr. Philip Willke
Dr. Philip Willke Affiliation: Karlsruhe Institute of Technology, Physikalisches Institut, Karlsruhe, Germany E-mail address: [email protected] Date of birth: 03.10.1987 Nationality: German Website: www.atomholics.de Research Experience 10/2020 - current: Independent Junior Research Group Leader in the Emmy-Noether Program of the German Science Foundation, Karlsruhe Institute of Technology, Physikalisches Institut, Karlsruhe, Germany Starting my own lab on Quantum Coherent Control of Atomic and Molecular Spins on Surfaces 06/2020 – 10/2020: Young Investigator Group Preparation Program of the Karlsruhe Institute of Technology, Physikalisches Institut, Karlsruhe, Germany Preparation to set up my own lab, acquiring equipment 05/2018 - 05/2020: Postdoctoral Researcher and Feodor-Lynen Fellow (05/2018-05/2019), IBS Center for Quantum Nanoscience and Ewha Womans University, Seoul, South Korea (Advisor: Prof. Andreas Heinrich, Prof. Taeyoung Choi) Setting up a new lab for electron spin resonance scanning tunneling microscopy at the newly founded Center for Quantum Nanoscience 02/2017-04/2018: Postdoctoral Researcher at the IBM Almaden Research Center (CA, USA, Advisor: Christopher Lutz, Prof. Andreas Heinrich) Pioneering the field of electron spin resonance scanning tunneling microscopy 12/2013-01/2017: PhD at Georg-August Universität Göttingen (Summa cum Laude), Scanning Tunneling Microscopy group (Advisor: PD Dr. Martin Wenderoth) Thesis title: Atomic-scale transport in graphene: the role of localized defects and substitutional doping