Annual Report 2014-15 Transforming health and wellbeing through research and innovation

ISSN 1918-3232 (Online) Annual Report (Alberta Innovates – Health Solutions) 2014-15 Annual Report TABLE OF CONTENTS

Executive Summary...... 2-3 Accountability Statement...... 4 Message from Board Chair...... 5 Key Research and Innovation Initiatives...... 6-15 Management’s Discussion and Analysis...... 16-17 Operational Overview...... 18 Consolidated Financial Statements...... 19-38 Appendix A: AIHS Funding Awards...... 39-42 Appendix B: Currently Funded Projects & People...... 43-63

2014-15 ANNUAL REPORT 1 EXECUTIVE SUMMARY

Albertans face many issues when it comes to their health and their health care system. There are pockets of excellence in health care but there remain major variations in quality, access and outcomes. Our system is the most expensive in Canada. The parts of the system are not fully integrated, which is a particular challenge for the growing numbers of people with multiple chronic conditions, frailty, and mental health issues. Alberta Innovates – Health Solutions (AIHS) focuses on finding ways to accelerate the creation and uptake of research evidence to support health and health system effectiveness, quality and efficiency. The benefits to Albertans will be better ways of delivering care, improved patient experiences and outcomes, and cost savings.

AIHS is able to perform a unique role in our Mobilizing expertise and input from all stakeholders province to address some of these issues through vested in contributing to better health and health health research and innovation support. This role services is the right way to tackle enormously complex has three overlapping dimensions: problems that affect our people and our province. One of this past year’s highlights was the development • Partner, broker and facilitator of targeted, high of a strategic provincial partnership—the Health impact health initiatives; Research and Innovation Collaboratory (HRIC)— • Catalyst for major capacity development in core formed to accelerate research and innovation into areas critical to the support and competitiveness health and healthcare. In addition to AIHS, this of our provincial health research and innovation partnership includes: environment; • Funder of high quality, priority health research • Alberta Health Services (AHS), our health delivery activity and enabler for moving the resulting system; innovations into use and development. • the ministries of Health and Innovation and Advanced Education; • Alberta Innovates – Technology Futures (AITF); • the Alberta Academic Health Network (AHN), representing our universities; and • community care providers, represented by the Alberta Medical Association (AMA).

2 ALBERTA INNOVATES – HEALTH SOLUTIONS This is the first time AIHS has formed such a The new focus on partnered activity heightens the partnership for system coordination on major projects need for reporting on the impact of our investments with the potential for transformative changes in in research and innovation to our funding health delivery. partners and to the people of Alberta. AIHS has a performance management and evaluation unit Initial HRIC processes, platforms and broad system that has set the standard in the province for how priorities were developed over the past year to to conduct impact assessments. In September, demonstrate proof of concept for this collaborative 2014 AIHS and international partners, AQuAS way of thinking and doing. The goal is to develop and Rand Europe, offered the first International such a powerful value proposition that we attract School for Research Impact Assessment in Banff. partners from all sectors and areas of the world who Sixty participants from Alberta, the rest of Canada want to work with us and invest in Alberta to deliver and from around the world participated in the optimal health and healthcare. intensive, hands-on school to learn how to conduct performance measurement and management. Within AIHS, we created the Partnership Office Building capacity to determine what works and whose members have strong established relationships what doesn’t in our broad health system is why with academia, industry and the health system. performance management and evaluation is a The Partnership Office serves as a receptor for the defined platform for the HRIC. opportunities arising through HRIC or from other organizations and also takes a proactive approach— The ongoing successes of our health research and identifying new opportunities and delivering them innovation environment in Alberta are sustained with partners. The results of their work are new through AIHS’s investment in a wide spectrum partners to the ecosystem who bring new funding of activity in our research community with nearly to Alberta’s health researchers and innovators; $77.5 million dollars out the door in this last fiscal new grants that focus on health system issues and year. Over the past five years, the total of AIHS the development of province-wide approaches to investments in health research and innovation is common issues such as data use. nearly $400M dollars, with most of that funding streamed to our provincial universities. We also saw the further development of Alberta’s SPOR SUPPORT Unit, a $48 million initiative All of our activities aligned and will continue to jointly funded by AIHS and CIHR. The Unit—a align with the strategies and priorities identified virtual expertise and services hub for patient- by the Government of Alberta and our partners in oriented researchers in Alberta and the North West Alberta’s research and innovation ecosystem. We Territories—now has academic Leads appointed for are proud to uphold excellence and relevance in each of the seven platforms who are preparing for the the area of health research and innovation for the Unit opening its doors for business later in 2015. province and for the ultimate benefit of Albertans.

2014-15 ANNUAL REPORT 3 ACCOUNTABILITY STATEMENT

The Alberta Innovates – Health Solutions annual report for the year ended March 31, 2015 was prepared under the Board’s direction in accordance with the Alberta Research and Innovation Regulation, the Fiscal Management Act, and ministerial guidelines established pursuant to the Fiscal Management Act. All material economic, environmental, or fiscal implications of which we are aware have been considered in the preparation of this report.

[Original signed by Robert A. Seidel, QC]

Robert A. Seidel, QC CHAIR, BOARD OF DIRECTORS ALBERTA INNOVATES – HEALTH SOLUTIONS

4 ALBERTA INNOVATES – HEALTH SOLUTIONS MESSAGE FROM BOARD CHAIR

On behalf of the board of directors of Alberta Innovates – Health Solutions, I am very pleased to speak to our organization’s accomplishments and unwavering dedication to our strategic direction, especially in light of the tragic loss of our visionary president and CEO, Dr. Cy Frank, on March 5, 2015. Thanks to internal restructuring in late 2014 by Cy and his skilled management team, AIHS is in an optimal position to continue pursuing its goals: to deliver health, social and economic gains for Albertans from our support of health research and innovation.

The corporation’s home with Alberta Health and strengths and supports to achieve greater national closer alignment to the health system means our and global competitiveness and impact on health. collaborations, partnerships and investments are We support highly rated health research activity and having real and beneficial effects on health and the the innovations that result from that activity with health system. There is a “can-do” attitude that is the goal of better health and wellbeing for Albertans. bringing people and organizations together like never We contribute to the intellectual capacity at our before to really advance and change how we do things universities by funding top calibre people—from for maximum value. Cy Frank’s vision was that the trainees to internationally acclaimed scientists— assets of our broad health system have the potential to working in every area of health research. yield more health and wealth than any other resource we have in Alberta. We are proud to do our utmost to The sum total of the year is impressive despite the make that vision a reality. blow of losing Dr. Frank. I commend the Board, the leadership team at AIHS and all of our staff for We serve the people of Alberta through several areas continuing to advance the corporation’s directions of focus. We seek and broker partnerships with and maintain outstanding operations. other agencies, government departments, academia, the health system and industry to bring know-how from these sectors into approaches to solve health issues, and in doing so, we leverage the public [Original signed by Robert A. Seidel, QC] dollars entrusted to us and maximize the impact of research results. With partners, we are leading the development of agreed-upon areas of core support Robert A. Seidel, QC for the entire health research and innovation system so that we see a much greater growth in capacity, CHAIR, BOARD OF DIRECTORS resources and application of knowledge. The goal ALBERTA INNOVATES – HEALTH SOLUTIONS is to provide provincial research activities with the

2014-15 ANNUAL REPORT 5 KEY RESEARCH AND INNOVATION INITIATIVES

AIHS’s mandate is to support research and innovation which improves the health and wellbeing of Albertans and creates social, health and economic benefits for our province and its people.

To fulfill this mandate and to deliver on the 2014- GOAL 1 17 Business Plan, AIHS focused on five goals: Promote strategic research and innovative • Strategic Investments investments through the development of new • Platforms for Success programs and support of existing programs* • Relationship Development • Impact Evaluation and Acceleration OUTCOMES • Building, Mobilizing and Accessing Capacity • Invest in collaborative, interdisciplinary, multi- In this section, we outline our key achievements sectoral, and/or multi-institutional research with a for this year and some stories illustrating focus on achieving solutions that address complex them. These achievements rely on people and health problems or issues through our Collaborative organizations within the provincial environment Research and Innovation Opportunities (CRIO) working together towards a common goal – funding. whether it be providing funding or collaborating • Invest and support networks of health researchers with researchers in a different field or at a different and clinical practitioners across the continuum of institution or in a different country. AIHS care, with an emphasis on population health and investments in research and innovation usually community and primary care, which can reassess involve multi-year commitments and it must be potentially inefficient activities within the health noted that many of the achievements highlighted system and identify sustainable solutions to improve here are the results of (sometimes) years of patience overall quality of care and value for money in the and diligence. system. Funded by AIHS-Alberta Health Services Partnership for Research and Innovation in the Health System (PRIHS) awards. • Invest in innovative, relevant, priority areas of cancer research, with investment in priority cancer prevention research from the Alberta Cancer Prevention Legacy Fund (ACPLF).

* please see Appendix A for a complete listing of current AIHS funding programs

6 ALBERTA INNOVATES – HEALTH SOLUTIONS Actual Forecast Actual Performance Measure(s) 2013-14 2014-15 2014-15

CRIO Investment $11.6M $18.0M $11.5M PRIHS Investment $2.4M $5.0M $0.1M ACPLF Investment $10.9M $14.0M $9.8M

** Investment values recognize the funds released during the period rather than the total value committed. Funds are released when authorized and eligibility criteria, if any, are met based on terms and conditions of the awards.

KEY ACHIEVEMENTS Funded in part by a CRIO Team grant, CRIO grants support collaborative research in priority areas for Alberta that engages researchers completed an international knowledge-/end-users, produces new randomized controlled trial showing that a clot knowledge, and helps translate knowledge retrieval procedure, known as endovascular to improve health and the healthcare system. treatment (ET), can dramatically improve patient AIHS offers: CRIO Team, which can provide outcomes after an acute ischemic stroke. The up to $5 million over 5 years to a large study, led by researchers at the University of ’s interdisciplinary team; CRIO Project which Hotchkiss Brain Institute (HBI), shows a dramatic offers up to $2.5 million over 5 years to a improvement in outcomes and a reduction in deaths group of three or more collaborators; and, from stroke. The results of this study were published CRIO Project which provides up to $750,000 in the February 11, 2015 online edition of the New over 3 years to collaborators focused on a England Journal of Medicine (NEJM). Overall, positive defined project. AIHS invested $11.5M in outcomes for patients increased from 30 per cent to existing CRIO grants during 2014-2015. A 55 per cent. In many cases, instead of suffering major further $50.0M is committed to these multi- neurological disabilities, patients went home to resume year grants over the next three years. their lives. The overall mortality rate was reduced from two in 10 patients for standard treatment of care to one in 10 patients – a 50 per cent reduction with ET. The senior author of the study was Dr Michael Hill, professor in the Cumming School of Medicine’s departments of clinical neurosciences, and radiology and a neurologist with the Calgary Stroke Program of Alberta Health Services (AHS). The study was funded by Alberta Innovates-Health Solutions, The Heart and Stroke Foundation of Canada, and Medtronic, along with generous donations to the HBI Stroke Team and the Calgary Stroke Program.

2014-15 ANNUAL REPORT 7 CRIO Population Resiliency - The Government of Alberta Funded by a CRIO Team grant, designated $50 million to support flood victims’ immediate public health researchers and future mental health needs in the aftermath of the 2013 Drs. Paul Veugelers and flooding in Southern Alberta. Three million dollars of that funding was allocated to an Alberta Health-AIHS partnership Arto Ohinmaa are evaluating to establish the CRIO – Population Resiliency award. The several dozen health promotion Award focuses on developing and strengthening population strategies in Alberta to find out resiliency before and after catastrophic events in two areas: which are most effective in terms aboriginal and child and youth populations. Two grant of health and economics. By the applications were successful: third year (2016/17) of the five-year project, researchers will have a good idea of what the province is spending Dr. Julie Drolet (University of Calgary), Dr. Robin money on and how each strategy Cox (Royal Roads University) and Dr. Caroline measures up to a number of criteria, McDonald-Harker (Mount Royal University) are including mental health, learning, leading the 3-year Alberta Resilient Communities obesity and heart health. They’ll share project (ARC) which works with children, youth their findings with policymakers. Information collected will help and their communities to inform and strengthen politicians make “fully informed child and youth mental health and enhance decisions” about how the province disaster preparedness, reduce risk and build invests in health promotion. resilience in Southern Alberta. ARC, a CRIO Program grant, will help better understand the social, economic, health, cultural, spiritual and personal factors that contribute to child and youth resiliency while empowering them, their families and communities to build resiliency.

A CRIO Team grant supports Prediction and Understanding of Resilience in Alberta Families: Longitudinal Study of Disaster Responses (PURLS). The leaders for this 3 year project are: Dr. Dawn Kingston (University of Alberta), Dr. Andrew Greenshaw (University of Alberta), Dr. Suzanne Tough (University of Calgary) and Dr. Sheila McDonald (Alberta Health Services).

8 ALBERTA INNOVATES – HEALTH SOLUTIONS The Partnership for Research and Innovation in the Health System (PRIHS) is a partnership Funded by a 2013 AIHS PRIHS grant, between Alberta Innovates – Health Solutions Dr. Mary Forhan and her co-principal (AIHS) and Alberta Health Services (AHS) aimed investigators Dr. Jeffrey Johnson and at improving health outcomes for patients across Dr. Arya Sharma collect data on the Alberta. This partnered funding opportunity targets prevalence of obesity, length of stay high impact research activities within the AHS and cost of care in adult cancer patients Strategic Clinical Networks (SCNs) that align with at the Cross Cancer Institute, cardiac the priorities identified in the Alberta’s Health surgery patients across Alberta, and Research and Innovation Strategy (AHRIS) and the AHS Health Plan. PRIHS supports networks of children at the Glenrose Rehabilitation health researchers and clinical practitioners across the Hospital. The Diabetes, Obesity and continuum of care, with an emphasis on population Nutrition Strategic Clinical Network are health and community and primary care, that can also on board to help determine the longer reassess potentially inefficient activities within the hospital stays. One of the project’s goals health system and identify sustainable solutions to includes developing best practice guidelines improve overall quality of care and value for money for providing quality care for rehabilitation in the health system. Ten 2014 PRIHS grants, patients who have obesity. The team will also representing a total investment of approximately survey healthcare providers about the gaps in $7.2 million over three years, were approved and training for the care of patients with obesity. announced during the 2014/2015 year. A total of $12.4M is committed to PRIHS over the next three years, a grant jointly funded by AIHS and AHS.

In 2014/15, AIHS developed the Cancer Prevention Research Opportunity (CPRO), funded through the Alberta Cancer Prevention Legacy Fund (ACPLF) and part of the CRIO funding portfolio. Lowering rates of cancer and improving outcomes for cancer patients through prevention strategies and lifestyle change would be a major health, social and economic gain for everyone. To support that that goal, CPRO was designed to support research approaches that create new knowledge in the area of cancer prevention and screening and move that new knowledge and evidence into use in the health system, in communities, in workplaces, and in the daily lives of Albertans. CPRO grants will be awarded in 2015/16.

2014-15 ANNUAL REPORT 9 GOAL 2 KEY ACHIEVEMENTS Facilitate, develop and support platforms The Strategy for Patient-Oriented Research SUPPORT that address strategic outcomes and Unit is one way Alberta Innovates – Health Solutions and its partner, the Canadian Institutes for Health objectives Research (CIHR), are supporting patient engagement research. The Unit is made up of seven platforms that OUTCOMES offer researchers expertise and service in core areas • Develop and implement the seven province-wide such as data support and service, methods support and platforms of the Alberta SPOR SUPPORT Unit: development and pragmatic clinical trials. Alberta’s Data Platforms and Service; Methods Support SPOR SUPPORT unit platforms held a competition and Development; Health Systems Research, for the Leads positions of the seven platforms during Implementation Research and Knowledge the spring and summer of 2014, which resulted in the Translation; Pragmatic Clinical Trials; Career appointments of nine individuals as Leads or Joint Development in Methods and Health Services leads. The platform Leads—alongside the Steering Research; Consultation and Research Services; Committee and other partners—are working on the and Patient Engagement. processes by which patient-oriented researchers can access the services, expertise and resources they need. • Implement the Alberta Health Research Ethics Harmonization (HREH) initiative to achieve Significant work has been achieved with the a streamlined, effective, collaborative and HREH initiatives. The key areas of focus have integrated health ethics model, supported by been: governance, reciprocity, data sharing and appropriate technology. common tools/processes. Under governance, the • Assess the requirements for Data Access and inaugural meeting of the HREH Steering Committee Platforms through partnerships and public was held on December 1, 2014. The reciprocity engagement. Develop a Data and Data Analytics agreement was signed by partners in 2014. Work plan with inputs and support from the Provincial on the implementation of the Institutional Research Health Analytics Network (PHAN), Alberta Information Services Solution (IRISS) platform Health and Alberta Health Services. continued to further support harmonized technical efforts. Lastly, AHS and Covenant Health have provided access to information which will help streamline research processes and reduce the amount of documentation required for submission.

Actual Forecast Actual Performance Measure(s) 2013-14 2014-15 2014-15

% Implementation of SPOR platforms 50% 50% 50% % Implementation of HREH approach 75% 75% 75%

10 ALBERTA INNOVATES – HEALTH SOLUTIONS AIHS, in collaboration with partners, advanced the development of the provincial Data Analytics platform. Activities included the successful recruitment of a project manager for the platform; the scoping of a platform Project Charter and the formulation integrated secondary use data platform working groups.

Dr. Virginia Vandall-Walker is the lead for the Unit’s patient engagement platform. She is an Associate Professor in the Faculty of Health Disciplines graduate program at Athabasca University, and a member of the Canadian Association of Critical Care Nurses, the Canadian Council of Cardiovascular Nurses, and the International Family Nursing Association. Since patients and their families know best how their conditions affect them, they are the logical starting point for researchers in the development of meaningful research questions. If patients and family are involved from the outset, then researchers can be confident that the research questions investigated are ones that patients would like answered. While a patient-centered approach seems logical, in research initiatives it’s not as common as one would think. Dr. Vandall- Walker’s challenge is to find ways to help others understand the benefits of patient engagement.

2014-15 ANNUAL REPORT 11 GOAL 3 OUTCOMES Engage and strengthen relationships • Develop an AIHS Partnership Office and the and identify new relationships to achieve related business plan. sustainable impact • Create valuable stakeholder engagement and outreach initiatives including: SCN Connects, Engaging Experts event in June.

Actual Forecast Actual Performance Measure(s) 2013-14 2014-15 2014-15

$ Attracted through partnerships (inc. $14.5M $10.0M $14.4M partner administered funds) # of stakeholder engagement initiatives 2 2 2

KEY ACHIEVEMENTS

In June, AIHS hosted a visit from The SCN Connects event at The Banff Centre Professor Dame Sally Davies, the Chief attracted 250 participants from various Medical Officer of the UK. Professor stakeholder groups including policy makers, Davies met with the Premier, the researchers, clinicians and patients. The keynote Minister of Health, the AIHS Board, the speaker was Brent James, who is known internationally Executive Team of AHS; the Executive for his work in clinical quality improvement, patient Team of Alberta Health; representatives safety, and the infrastructure that underlies successful from the UA and from ARIA. Professor improvement efforts, such as culture change, data Davies also gave a public talk as part of systems, payment methods, and management roles. The Health Policy Speakers Series jointly organized by AIHS and the Institute of Health Economics. Professor Davies shared her The International School on Research Impact experiences in her role in guiding government Assessment (ISRIA) jointly hosted by AIH, decisions on all matters of public health, AQuAS and Rand Europe was held for the first including such issues as superbugs, drug trials time in Alberta in September. and obesity as well as the development of the The School provided National Institute for Health Research in an intense hands-on workshop for 60 participants to 2006 with a budget of £1 billion. learn the tools and methodology for evaluating the impact of research funding and investment.

12 ALBERTA INNOVATES – HEALTH SOLUTIONS The AIHS Partnership Office was constituted during the organizational realignment in December 2014 and held its first meeting in January 2015.It is composed of executive-level representatives who have strong relationships with academia, industry and the health system. Until the passing of Dr Frank on March 5, it was chaired by the Chief Partnership Officer (who then took the role of Interim CEO). It is now chaired by the Vice President, Innovations and Initiatives. The Partnership Office works under a Terms of Reference and has developed a set of goals. The Programs and Projects business units were realigned into Innovations and Initiatives to ensure a clearer line of sight to the work of the Partnership Office.

GOAL 4 KEY ACHIEVEMENTS Accelerate and evaluate the impact of SPARC is a brand for a collaborative partnership research and innovation in the system focused on using research and innovation efforts to meet patient needs while delivering health, social and economic gains for Albertans. The guiding OUTCOMES principle of SPARC is to integrate research and • Develop a business plan for the Strategic innovation to produce better solutions and to Partnership to Accelerate Research and Innovation eliminate existing inefficiencies, with evidence into Health Care. (SPARC)***. and to meet current and new needs. The process • Influence the environment towards the use behind SPARC is to co-identifiy, co-determine, of assessment techniques and common tools, co-develop and co-deliver solutions among HRIC metrics, and processes used by AIHS and partners. During 2014-2015, a plan for SPARC collaborators that impact strategic capacity was developed and reviewed by HRIC. HRIC funding initiatives, industrial collaborations, and is the oversight body created to clarify roles and programs for regional innovation. responsibilities, integrate and prioritize initiatives and find synergies between member organization on initiatives of health research and innovation in Alberta. The on-going activities of the HRIC enable the SPARC brand and process.

Actual Forecast Actual Performance Measure(s) 2013-14 2014-15 2014-15

Complete business plan for SPARC n/a 100% 100%

2014-15 ANNUAL REPORT 13 In conjunction with HRIC partners, AIHS assisted in the development of a common performance AIHS is developing the “Implementing management framework for Alberta health research Health Research Impact Assessments: and innovation. An Intensive Training Course” to be held in June 2015. ***SPARC members AIHS, Alberta Health, Innovation This four day course and Advanced Education, Alberta Health Services, the targets building capacity in Alberta (and Academic Health Network (universities), community Canada) in health research impact assessment care providers (Alberta Medical Association) and (HRIA) and provide a common language, Alberta Innovates – Technology Futures work together approach and tools for the planning and to build a research evidence-informed health system that implementation of HRIA. meets the needs of all patients and realizes health, social and economic gains for Albertans.

GOAL 4 OUTCOMES Build and mobilize capacity in the health • Provide opportunities for trainees to gain broad research and innovation eco-system experience within the health research environment to facilitate success in launching careers in academia, industry, government or elsewhere.

Actual Forecast Actual Performance Measure(s) 2013-14 2014-15 2014-15

Funding for Trainees programs $9.9M $12.5M $9.0M

KEY ACHIEVEMENTS Total # Supported AIHS provided support to a wide New in by AIHS as at range of trainees – from Grade 2014/15 March 31, 2015 11 students working in Alberta’s HYRS students 50 0 universities’ labs in the summer to postgraduate fellows working Summer Students 163 0 towards their first appointment in Media Fellowship 2 0 academia or beyond. Graduate Studentships 38 130 Post graduate fellows 37 68 MD/PhD 3 20 Clinician Fellowships 10 34

14 ALBERTA INNOVATES – HEALTH SOLUTIONS Tamara Germani is an AIHS clinician fellow completing a PhD in pediatrics. She is working on a research project which looks at how preschoolers with autism get along with others. In the first part of the project, Germani is surveying families, educators and clinicians (including occupational therapists, physicians and psychologists) from across Canada. Next, she will help develop a new classification system to identify children’s skills (such as playing with or beside another child, sharing toys and talking with others), then ask caregivers dealing with autism to comment on the system. When working as an occupational therapist helping children with autism spectrum disorder (ASD) relate to other kids, she noticed parents and teachers tended to focus on what kids couldn’t do—rather than what they could. She hopes that her research project will help provide a snapshot of a child’s abilities that caregivers can tap into and help promote more positive awareness from the children themselves.

The PLUS Option is a component of the Graduate Studentship award that provides Perla Cota-Elizondo has a one year term with trainees with the opportunity to gain valuable Resverlogix, a biotechnology company that experience and additional skills beyond those develops drugs for cardiovascular disease, acquired through their direct graduate research based in Calgary and San Francisco. Perla training. Up to one year of additional support works with the business development team, which is may be requested for the PLUS Option, to be in charge of the bridging science and business teams utilized at any point during the tenure of the within the company. The opportunity will provide award or up to six months following the award her with mentorship and develop her skills in completion. Trainees can utilize the opportunity researching competitive intelligence, grant writing, to seek training or internship opportunities in required reporting and business development. business, education, industry, government and/ or health policy, within clinical or other health research related environments. Lauren Killip has a one year term with Focal The PLUS Option was initiated several years Healthcare Inc. as a Business Development ago, and as expected students are waiting until Manager. Focal Healthcare Inc. based in the end of the award to apply for this Option. Toronto, is developing a medical device To date, AIHS has received 11 applications. Six for the diagnosis and treatment of prostate are implemented and five are under review. Two cancer. Lauren will gain mentorship, business and PLUS Option awards were made in 2014-15. industry experience that will expand her skills sets beyond those attained from her graduate research training.

2014-15 ANNUAL REPORT 15 MANAGEMENT’S DISCUSSION AND ANALYSIS

The results presented in AIHS’s audited financial statements are shaped by our mandate from the Government of Alberta: to provide leadership for Alberta’s health research and innovation enterprise by directing, coordinating, reviewing, funding and supporting priority health research and innovation activities.

AIHS’s investments are targeted to the following outcomes: development and growth of the health sectors, the discovery of new knowledge, and the application of that knowledge to improve the health and wellbeing of Albertans. The major focus of AIHS’s activity is on making quality investments relevant to system needs and priorities.

FINANCIAL POSITION REVENUE

The Statement of Financial Position shows net Operating and unrestricted grants are recognized assets of $48.6 million and cash of $95.2 million. as revenue in the year the transfers are received or AIHS has $184.7 million of contractual obligations receivable. Externally restricted revenue, including over the next five years (see note 13) which will partnership revenue, is recognized as revenue in become liabilities in future periods. The growing the period in which the resources are used for the net assets balance reflects the increasing future purpose specified. year commitments that are not yet recognized as liabilities. Cash of $95.2 million includes restricted Cash received from Government of Alberta Grants cash of $38.1 million. The restricted cash reflects was as budgeted. However, as a portion of the payments received for a specified purpose. Funds received restricted funds for ACPLF were not are recorded as restricted cash and deferred revenue expended during the period, the revenue recognized until the resources are used for the purpose specified. was $3.9 million lower than budgeted and the Higher unrestricted cash balances reflect the delayed balance was recorded as deferred revenue. timing of the implementation of new programs, Partnership revenue was $4.3 million lower than platforms and initiatives where commitments have budget as the cash was received but revenue was been made, however the activity to recognize the deferred as the associated program spending was liability will take place in a later period. delayed into 2015-2016.

Investment income is interested income generated by the Consolidated Cash Investment Trust Fund. The higher than budgeted cash balance generated higher than budgeted interest during the year.

16 ALBERTA INNOVATES – HEALTH SOLUTIONS EXPENDITURES COMMITTED FUNDING

• Strategic investments includes Alberta Heritage AIHS committed funding is money allocated Foundation for Medical Research (AHFMR) Legacy over a time period for a specific purpose. In some programs, the Collaborative Research and Innovation cases, AIHS receives cash through partnerships Opportunities (CRIO) portfolio, Translational which require corresponding funding from Health Chairs as well as funding for new strategic AIHS. To recognize the expense the grant must opportunities. Timing of the implementation and be approved, all eligibility criteria met, and the awarding of new funding opportunities, as well as expense unavoidable. In other cases, funding is continued support of legacy programs, resulted in a allocated to AIHS for the purposes of fulfilling an timing delay of $13.0 million as compared to budget. agreement approved by AIHS Board of Directors. The supplemental draw on the AHFMR • Platforms for Success expenses include SPOR Endowment is an example of an annual allocation Support unit funding as well as other platform of funding to AIHS from the government to help spending such as the Ethics Innovations initiatives. the provinces universities manage the transition Actual spending was $12.4 million lower than of researchers from the Legacy funding program, budgeted, $10.5 million of which related to the retain outstanding talent and sustain research timing of SPOR implementation. capacity and strength. • Relationship Development expenses include stakeholder engagement activities and the administration of partner restricted funds. Expenses were $13.5 million lower than budgeted as the development of programs delayed the recognition of commitments to liabilities with partner funds until 2015-2016. • Expenditures related to Impact Evaluation and Acceleration were $0.2 million lower than budgeted as a result of delayed timing of Knowledge Translation initiatives. • Building Capacity expenditures of education and career development awards as well as platform development costs were $3.9 million lower than planned due to timing of development awards. • Emerging opportunities of $9.8 million were budgeted but were deferred until 2015-2016. • Operations expenses were $1.1 million lower than budget. Lower salaries and benefits as a result of vacant positions combined with lower spending on supplies and services, resulted in the positive variance.

2014-15 ANNUAL REPORT 17 OPERATIONAL OVERVIEW

During 2014-15, AIHS operated the following core AIHS governance remained stable throughout the platforms, partnerships and initiatives: year. There were no changes to the bylaws, code of conduct, conflict of interest policies or intellectual • Partnership Office property practices during the year. The organization • SPOR SUPPORT Unit continues to follow guidance provided by the Government of Alberta on appropriate policies and • Strategic Provincial Partnership for Accelerating procedures for transparency and accountability. Health Research and Innovation in Care platforms

• Collaborative Research and Innovation Grants received from the Government of Alberta Opportunities (CRIO): Projects, Programs and totaled $98 million: the annual base grant of $86 Teams million from Alberta Health and $12.5 from the • Partnership for Research and Innovation in the ACPLF, also from Alberta Health. An additional Health System (PRIHS) $5.5 million was from partnership and investment • Early Career Development and Training Programs revenues. Total expenses were $87.6 million, • Translational Health Chairs resulting in net operating surplus of $12.7 million. • Industry Partnered Translation Fund • Independent Investigator Awards • Cancer Research grants and awards as supported through the Alberta Cancer Prevention Legacy Fund • Ethics & Innovation Initiatives • Performance Management and Evaluation

In late 2014, AIHS realigned its organization structure in order to better support the organization’s new focus on partnerships and catalyzing provincial platform development. We created the Partnership Office and the Provincial Platforms & SPOR business unit. Members of the leadership team were reassigned in order to reflect these operational priorities. In March, further adjustments were made to the organizational structure following the passing of Dr. Frank – most notably, Dr. Pamela Valentine was named Interim CEO and Mr. Reg Joseph was assigned as Chair of the Partnership Office.

18 ALBERTA INNOVATES – HEALTH SOLUTIONS Alberta Innovates – Health Solutions CONSOLIDATED FINANCIAL STATEMENTS MARCH 31, 2015

Management’s Responsibilities for the Financial Statements

Independent Auditor’s Report

Consolidated Statement of Financial Position

Consolidated Statement of Operations

Consolidated Statement of Cash Flows

Notes to the Consolidated Financial Statements

Schedule 1 – Expenses Detailed by Object

Schedule 2 – Salary and Benefits Disclosure

Schedule 3 – Related Party Transactions

Schedule 4 – Budget Reconciliation

2014-15 ANNUAL REPORT 19 MANAGEMENT’S RESPONSIBILITY FOR REPORTING

The accompanying financial statements are the Alberta Innovates Health Solutions Board of responsibility of management and have been Directors carries out their responsibility for the reviewed and approved by Senior Management. The financial statements through the Finance and Audit financial statements were prepared in accordance with Committee. The Committee meets with management Canadian Public Sector Accounting Standards, and and the Auditor General of Alberta to review of necessity, include some amounts that are based on financial matters, and recommends the financial estimates and judgement. statements to Alberta Innovates Health Solutions Board of Directors for approval upon finalization of To discharge its responsibility for the integrity and the audit. The Auditor General of Alberta has free objectivity of financial reporting, management access to the Finance and Audit Committee. maintains a system of internal accounting controls comprising written policies, standards and The Auditor General of Alberta provides an procedures, a formal authorization structure, and independent audit of the financial statements. satisfactory processes for reviewing internal controls. His examination is conducted in accordance with This system provides management with reasonable Canadian Generally Accepted Auditing Standards assurance that transactions are in accordance with and includes tests and procedures, which allow him governing legislation and are properly authorized, to report on the fairness of the financial statements reliable financial records are maintained, and assets prepared by management. are adequately safeguarded.

[Original signed by Pamela Valentine, PhD] [Original signed by Maureen Fromhart, CMA]

Dr. Pamela Valentine Maureen Fromhart INTERIM CEO VICE PRESIDENT, CORPORATE SERVICES ALBERTA INNOVATES – HEALTH SOLUTIONS ALBERTA INNOVATES – HEALTH SOLUTIONS

May 27, 2015

20 ALBERTA INNOVATES – HEALTH SOLUTIONS Independent Auditor’s Report

To the Board of Directors of Alberta Innovates—Health Solutions

Report on the Consolidated Financial Statements I have audited the accompanying consolidated financial statements of Alberta Innovates—Health Solutions, which comprise the consolidated statement of financial position as at March 31, 2015, and the consolidated statements of operations and cash flows for the year then ended, and a summary of significant accounting policies and other explanatory information.

Management’s responsibility for the Consolidated Financial Statements Management is responsible for the preparation and fair presentation of these consolidated financial statements in accordance with Canadian public sector accounting standards, and for such internal control as management determines is necessary to enable the preparation of consolidated financial statements that are free from material misstatement, whether due to fraud or error.

Auditor’s Responsibility My responsibility is to express an opinion on these consolidated financial statements based on our audit. I conducted my audit in accordance with Canadian generally accepted auditing standards. Those standards require that I comply with ethical requirements and plan and perform the audit to obtain reasonable assurance about whether the consolidated financial statements are free from material misstatement.

An audit involves performing procedures to obtain audit evidence about the amounts and disclosures in the consolidated financial statements. The procedures selected depend on the auditor’s judgment, including the assessment of the risks of material misstatement of the consolidated financial statements, whether due to fraud or error. In making those risk assessments, the auditor considers internal control relevant to the entity’s preparation and fair presentation of the consolidated financial statements in order to design audit procedures that are appropriate in the circumstances, but not for the purpose of expressing an opinion on the effectiveness of the entity’s internal control. An audit also includes evaluating the appropriateness of accounting policies used and the reasonableness of accounting estimates made by management, as well as evaluating the overall presentation of the consolidated financial statements.

I believe that the audit evidence I have obtained is sufficient and appropriate to provide a basis for my audit opinion.

Opinion In my opinion, the consolidated financial statements present fairly, in all material respects, the financial position of Alberta Innovates—Health Solutions as at March 31, 2015, and the results of its operations, its remeasurement gains and losses, and its cash flows for the year then ended in accordance with Canadian public sector accounting standards.

[Original signed by Merwan N. Saher, FCA]

Auditor General

May 27, 2015

Edmonton, Alberta

2014-15 ANNUAL REPORT 21 ALBERTA INNOVATES - HEALTH SOLUTIONS CONSOLIDATED STATEMENT OF FINANCIAL POSITION AS AT MARCH 31, 2015

2015 2014 (in thousands) Assets Cash (Note 6) $ 95,245 $ 62,573 Accounts Receivable and Other Assets (Note 8) 950 8,527 Tangible Capital Assets (Note 9) 841 943 $ 97,036 $ 72,043

Liabilities Accounts Payable and Accrued Liabilities (Note 10) $ 9,421 $ 11,971 Deferred Revenue (Note 11) 38,687 23,763 Benefit Plans (Note 12(b)) 328 378 $ 48,436 $ 36,112

Net Assets Accumulated Operating Surplus 48,600 35,931 $ 97,036 $ 72,043

Contractual Obligations (Note 13)

The accompanying notes and schedules are a part of these consolidated financial statements.

Approved by:

[Original signed by [Original signed by Robert Seidel,Robert Q.C. A. Seidel, QC] AubreyDr. Aubrey Tingle, TingleMD, PhD, FRCPC, FCAHS] Board of Directors, Chair Finance and Audit Committee, Chair

Robert Seidel, Q.C. Dr. Aubrey Tingle BOARD OF DIRECTORS, CHAIR FINANCE AND AUDIT COMMITTEE, CHAIR

22 ALBERTA INNOVATES – HEALTH SOLUTIONS ALBERTA INNOVATES - HEALTH SOLUTIONS CONSOLIDATED STATEMENT OF OPERATIONS YEAR ENDED MARCH 31, 2015

2015 2014 Budget Actual Actual (Schedule 4) (in thousands) Revenues

Government Transfers Government of Alberta Grants $ 101,794 97,932 100,363 Partnership Revenue 4,797 500 1,257 Other Revenue 984 933 1,054 Investment Income 450 882 593 108,025 100,247 103,267

Expenses (Schedule 1 and Note 2(b)(iii))

Strategic Investment 69,309 56,271 75,080 Platforms for Success 18,823 6,465 4,313 Relationship Development 16,187 2,698 4,299 Impact Evaluation and Acceleration 2,275 2,118 1,418 Building Capacity 13,850 9,901 10,865 Emerging Opportunities 9,750 - - Operations 11,266 10,125 9,298 141,460 87,578 105,273

Annual Operating Surplus (Deficit) $ (33,435) $ 12,669 $ (2,006)

Accumulated Surplus, Beginning of year 35,931 37,937 Accumulated Surplus, End of year 48,600 35,931

The accompanying notes and schedules are a part of these consolidated financial statements.

2014-15 ANNUAL REPORT 23 ALBERTA INNOVATES - HEALTH SOLUTIONS CONSOLIDATED STATEMENT OF CASH FLOWS YEAR ENDED MARCH 31, 2015

2015 2014 (in thousands)

Operating Transactions Annual Operating Surplus (Deficit) $ 12,669 $ (2,006) Non-Cash Items: Amortization of Tangible Capital Assets (Note 9) 269 223 Loss on Disposal of Tangible Capital Assets - 24 Deferred Revenue Recognized as Revenue (12,046) (15,230) 892 (16,989)

(Decrease) Increase in Accounts Receivable and Other Assets 7,577 (4,534) Decrease (Increase) in Accounts Payable and Accrued Liabilities (2,550) 10,205 Increase in Deferred Revenue Received/Receivable 26,970 28,768 Decrease in Benefit Plans (50) (50) Cash Provided by Operating Transactions 32,839 17,400

Capital Transactions Purchase of Tangible Capital Assets (Note 9) (167) (102) Cash Applied to Capital Transactions (167) (102)

Increase in Cash 32,672 17,298 Cash, Beginning of Year 62,573 45,275 Cash, End of Year $ 95,245 $ 62,573

The accompanying notes and schedules are a part of these consolidated financial statements.

24 ALBERTA INNOVATES – HEALTH SOLUTIONS ALBERTA INNOVATES – HEALTH SOLUTIONS NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS MARCH 31, 2015

NOTE 1 AUTHORITY AND PURPOSE

Alberta Innovates – Health Solutions (the Corporation) is a Provincial Corporation, as defined in the Financial Administration Act, that was established on January 1, 2010 and operates under the authority of the Alberta Research and Innovation Act. The mandate of the Corporation is to support the economic and social well-being of Albertans, health research and innovation activities that are aligned to meet Government of Alberta priorities, including, without limitation, activities directed at the development and growth of the health sector, the discovery of new knowledge and the application of that knowledge.

The Corporation is exempt from income taxes under the Income Tax Act.

NOTE 2 SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

These consolidated financial statements are prepared in accordance with Canadian public sector accounting standards (PSAS).

a) Reporting Entity and Method of Consolidation

The consolidated financial statements reflect the assets, liabilities, revenues and expenses of the reporting entity, which is comprised of the Corporation and the Alberta Foundation for Health Research (AFHR). The AFHR operates under the Alberta Companies Act and is a registered charitable organization for income tax purposes. The Foundation’s activities are directed to promote and support medical research. All intercompany balances and transactions have been eliminated on consolidation.

b) Basis of Financial Reporting

(i) Revenue Recognition All revenues are reported on the accrual basis of accounting. Cash received for which goods or services have not been provided by year end is recorded as deferred revenue. Externally restricted revenue, including partnership revenue, is recognized as revenue in the period in which the resources are used for the purpose specified. Funds received prior to meeting the criterion are recorded as deferred revenue until the resources are used for the purpose specified.

Operating and unrestricted grants are recognized as revenue in the year the transfers are received or receivable. Restricted grants are included in deferred revenue when received, and recognized as revenue when the Corporation meets the conditions of the grant.

2014-15 ANNUAL REPORT 25 ALBERTA INNOVATES – HEALTH SOLUTIONS NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS MARCH 31, 2015

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Cont’d)

Investment income includes interest recorded on the accrual basis where there is reasonable assurance as to its measurement and collection.

(ii) Government transfers Transfers from the Government of Alberta, other governments, and other government entities are referred to as government transfers.

Government transfers and the associated externally restricted investment income are recorded as deferred revenue if the terms for use of the transfer, or the terms along with the Corporation’s actions and communications as to the use of the transfer, create a liability. These transfers are recognized as revenue as the terms are met and, when applicable, the Corporation complies with its communicated use of the transfer.

All other government transfers, without terms for use of the transfer, are recorded as revenue when the transfer is authorized and the Corporation meets the eligibility criteria.

(iii) Expenses Expenses are reported on an accrual basis. The cost of all goods consumed and services received during the year are expensed.

Directly incurred expenses are costs the Corporation has primary responsibility and accountability for. In addition to operating expenses such as salaries and supplies, directly incurred expenses also include: • Amortization of tangible capital assets. • Pension costs which comprise of the cost of employer contributions for current service of employees during the year. • Valuation adjustments which include changes in the valuation allowances used to reflect financial assets at their net recoverable or other appropriate value. Valuation adjustments also represent the change in management’s estimate of future payments arising from obligations relating to vacation pay.

Grants are recognized as expenses when authorized, eligibility criteria, if any, are met, and a reasonable estimate of the amounts can be made.

26 ALBERTA INNOVATES – HEALTH SOLUTIONS ALBERTA INNOVATES – HEALTH SOLUTIONS NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS MARCH 31, 2015

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Cont’d)

(iv) Assets Financial Assets Financial assets are assets that could be used to discharge existing liabilities or finance future operations and are not for consumption in the normal course of operations. Financial assets of the Corporation are limited to financial claims, such as advances to and receivables from other organizations, employees and other individuals.

The Consolidated Cash Investment Trust Fund (CCITF) is managed with the objective of providing competitive interest income to depositors while maintaining appropriate security and liquidity of depositors’ capital. The portfolio is comprised of high-quality, short-term and mid-term fixed income securities with a maximum to maturity of three years.

Tangible Capital Assets Tangible capital assets of the Corporation are recorded at historical cost, which includes amounts that are directly related to the acquisition, design, construction, development, improvement, or betterment of the assets. Tangible capital assets are amortized on a straight-line basis over the estimated useful lives of the assets.

Tangible capital assets are written down when conditions indicate that they no longer contribute to the Corporation’s ability to provide services or when the value of future economic benefits associated with the tangible capital assets are less than their net book value.

(v) Net Assets Net assets represent the difference between the carrying value of assets held by the Corporation and its liabilities.

Canadian public sector accounting standards require a “net debt” presentation for the statement of financial position in the summary financial statements of governments. Net debt presentation reports the difference between financial assets and liabilities as “net debt” or “net financial assets” as an indicator of the future revenues required to pay for past transactions and events. The Corporation operates within the government reporting entity, and does not finance all its expenditures by independently raising revenues. Accordingly, these financial statements do not report a net debt indicator.

2014-15 ANNUAL REPORT 27 ALBERTA INNOVATES – HEALTH SOLUTIONS NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS MARCH 31, 2015

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Cont’d)

(vi) Liabilities Liabilities are recorded to the extent that they represent present obligations as a result of events and transactions occurring prior to the end of fiscal year. The settlement of liabilities will result in sacrifice of economic benefits in the future.

(vii) Employee Future Benefits The Corporation operates a defined contribution pension plan. Pension costs included in these consolidated financial statements are comprised of the cost of employer contributions for the current service of employees during the year. There are no unfunded liabilities with respect to pension and pension costs.

(viii) Valuation of Financial Assets and Liabilities The Corporation’s financial assets and liabilities are generally measured as follows:

Financial Statement Component Measurement Cash Amortized cost Accounts receivable and other assets Amortized cost Accounts payable and accrued liabilities Amortized cost

The Corporation has no assets or liabilities in the fair value category, has not engaged in foreign currency transactions and has no remeasurement gains or losses. Consequently, no statement of remeasurement gains or losses has been presented.

For financial instruments measured using amortized cost, the effective interest rate method is used to determine interest revenue or expense. Transaction costs are a component of cost for financial instruments measured using cost or amortized cost. Transaction costs are expected for financial instruments measured at fair value.

(ix) Measurement uncertainty The measurement of certain assets and liabilities is contingent upon future events; therefore, the preparation of these consolidated financial statements requires the use of estimates, which may vary from actual results. Management uses judgment to determine such estimates. In management’s opinion, the resulting estimates are within reasonable limits of materiality and are in accordance with the significant accounting policies summarized below.

28 ALBERTA INNOVATES – HEALTH SOLUTIONS ALBERTA INNOVATES – HEALTH SOLUTIONS NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS MARCH 31, 2015

NOTE 3 CHANGE IN ACCOUNTING POLICY

In June 2010 the Public Sector Accounting Board (PSAB) issued this accounting standard effective for fiscal years starting on or after April 1, 2014. Contaminated sites are a result of contamination being introduced into air, soil, water or sediment of a chemical, organic or radioactive material or live organism that exceeds an environmental standard. The Corporation adopted this accounting standard retroactively as of April 1, 2014 but without restatement of prior period results. The Corporation is required to recognize a liability related to the remediation of such contaminated sites subject to certain recognition criteria. For the fiscal year ended March 31, 2015, The Corporation has not identified any liability for contaminated sites.

NOTE 4 Future Accounting Changes

Future Accounting Changes In March 2015 the Public Sector Accounting Board issued PS 2200 – Related party disclosures and PS 3420 – Inter-entity transactions. These accounting standards are effective for fiscal years starting on or after April 1, 2017.

PS 2200 – Related party disclosures defines a related party and identifies disclosures for related parties and related party transactions, including key management personnel and close family members.

PS 3420 – Inter-entity transactions, establishes standards on how to account for and report transactions between public sector entities that comprise a government’s reporting entity from both a provider and recipient perspective.

Management is currently assessing the impact of these statements on the financial statements.

NOTE 5 BUDGET (in thousands)

A preliminary business plan with a budgeted deficit of $33,435 was approved by the Board on March 27, 2014 and the full financial plan was submitted to the Minister of Health. The budget reported in the statement of operations reflects the original $33,435 deficit.

2014-15 ANNUAL REPORT 29 ALBERTA INNOVATES – HEALTH SOLUTIONS NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS MARCH 31, 2015

NOTE 6 CASH (in thousands)

Cash in the amount of $95,245 (2014 - $62,573) include deposits in the Consolidated Cash Investment Trust Fund (CCITF) amounting to $95,096 (2014 - $62,451). Cash as at March 31, 2015 includes restricted cash of $38,137 (2014 - $15,730). As at March 31, 2015, securities held by the Corporation have a return of 1.2% per annum (2014: 1.2% per annum). Due to the short-term nature of CCITF investments, the carrying value approximates fair value.

NOTE 7 FINANCIAL RISK MANAGEMENT

The Corporation’s financial instruments include cash, accounts receivable and other assets and accounts payable and accrued liabilities. The Corporation is not involved in any hedging relationships through its operations and does not hold or use any derivative financial instruments for trading purposes.

The Corporation’s financial instruments are exposed to credit risk, market risk and liquidity risk.

a) Credit Risk Counterparty credit risk is the risk of loss arising from the failure of a counterparty to fully honour its financial obligations with the corporation. The Corporation’s accounts receivable are exposed to credit risk. Management manages this risk by continually monitoring the creditworthiness of counterparties and by dealing with counterparties that it believes are creditworthy.

b) Market Risk Market risk is the risk of loss from unfavourable change in fair value or future cash flows of a financial instruments causing financial loss. Market risk is comprised of currency risk, interest rate risk and price risk. The Corporation’s cash is exposed to interest rate risk. Management manages this risk by continually monitoring the Corporation’s deposits in the CCITF and their corresponding rate of return.

c) Liquidity Risk Liquidity risk is the risk that the Corporation will encounter difficulty in meeting obligations associated with its financial liabilities. The Corporation’s accounts payable and accrued liabilities are exposed to liquidity risk. Management manages this risk by continually monitoring cash flows.

30 ALBERTA INNOVATES – HEALTH SOLUTIONS ALBERTA INNOVATES – HEALTH SOLUTIONS NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS MARCH 31, 2015

NOTE 8 ACCOUNTS RECEIVABLE AND OTHER ASSETS (in thousands)

2015 2014 Gross Allowance for Net Net Amount Doubtful Realizable Realizable Accounts Value Value

Accounts Receivable $ 651 $ - $ 651 $ 8,422 Other Receivables 299 - 299 105 $ 950 $ - $ 950 $ 8,527 Accounts receivable are unsecured, non-interest bearing and reported at their net realizable value.

2014-15 ANNUAL REPORT 31 ALBERTA INNOVATES – HEALTH SOLUTIONS NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS MARCH 31, 2015

NOTE 9 TANGIBLE CAPITAL ASSETS (in thousands)

2015 2014 Computer Leasehold hardware Equipment improvements Total Total & software (b) (c)

Estimated Useful Life 5-10 years 3 years

Historical Cost (a) Beginning of Year $ 444 $ 1,851 $ 838 $ 3,133 $ 3,272 Additions 11 106 50 167 102 Disposals - (2) - (2) (241) $ 455 $ 1,955 $ 888 $ 3,298 $ 3,133

Accumulated Amortization Beginning of year $ 346 $ 1,094 $ 750 $ 2,190 $ 2,184 Amortization expense 12 214 43 269 223 Effect of disposals - (2) - (2) (217) $ 358 $ 1306 $ 793 $ 2,457 $ 2,190 Net Book Value at March 31, 2015 $ 97 $ 649 $ 95 $ 841

Net Book Value at March 31, 2014 $ 98 $ 757 $ 88 $ 943

(a) Equipment includes office equipment and furniture, and other equipment. (b) Leasehold improvements are amortized over the lease term. (c) Historical cost includes computer hardware and software work-in-progress at March 31, 2015 totaling $31 (2014 - $399)

NOTE 10 ACCOUNTS PAYABLE AND ACCRUED LIABILITIES (in thousands)

2015 2014 Accounts Payable and Accrued Liabilities $ 9,270 $ 11,718 Other 151 253 $ 9,421 $ 11,971

32 ALBERTA INNOVATES – HEALTH SOLUTIONS ALBERTA INNOVATES – HEALTH SOLUTIONS NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS MARCH 31, 2015

NOTE 11 DEFERRED REVENUE (in thousands)

2015 2014 Government Federal Non- Total Total of Alberta Government Government

Balance, beginning of year $ 19,958 2,912 893 $ 23,763 $ 10,225 Received/receivable during year 21,404 4,947 500 26,851 28,696 Restricted realized investment 119 - - 119 72 income Less amounts recognized as revenue (11,546) (250) (250) (12,046) (15,230) Balance, end of year $ 29,935 7,609 1,143 $ 38,687 $ 23,763

NOTE 12 BENEFIT PLANS (in thousands)

(a) Pension Plan

The Corporation participates in a Defined Contribution Pension Plan pension. The expense for this pension plan is $445 (2014 - $357). AIHS accounts for this plan on a defined contribution basis.

(b) Accrued Retirement Allowance

The Benefit Plans consists of the unfunded liability for the Corporation’s supplemental retirement plan, the benefits under which are paid for entirely by the Corporation when they come due. There are no plan assets. There are no active members remaining in the plan and two retired members eligible for benefits.

At March 31, 2015 these plans have net accrued liability of $328 (2014 - $378).

2015 2014 Benefit Plans – Beginning of year $ 378 $ 428 Interest cost 3 3 Benefits paid (53) (53) Benefit Plans – End of year $ 328 $ 378

2014-15 ANNUAL REPORT 33 ALBERTA INNOVATES – HEALTH SOLUTIONS NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS MARCH 31, 2015

NOTE 13 CONTRACTUAL OBLIGATIONS (in thousands)

Contractual obligations are obligations of the Corporation to others that will become liabilities in the future when the terms of those contracts or agreements are met.

2015 2014 Obligations under grants and awards and office premises $ 184,746 $ 205,624

Estimated payment requirements for each of the next five years and thereafter are as follows: Grants and Awards (a) Office Premises (b) Total

2015-16 $ 69,188 $ 601 $ 69,789 2016-17 45,894 682 46,576 2017-18 37,974 706 38,680 2018-19 24,471 698 25,169 2019-20 1,789 698 2,487 Thereafter 300 1,745 2,045 $ 179,616 $ 5,130 $ 184,746

(a) Grants and awards are recorded as commitments when all terms and conditions have been agreed to but eligibility criteria have not been met. (b) The Corporation has entered into a 104 month lease for office premises. The lease was re- negotiated on January 29, 2014 and expires on September 30, 2022.

NOTE 14 APPROVAL OF FINANCIAL STATEMENTS

These consolidated financial statements were approved by the Board of Directors.

34 ALBERTA INNOVATES – HEALTH SOLUTIONS ALBERTA INNOVATES - HEALTH SOLUTIONS Schedule 1 Expenses - Detailed by Object For the Year Ended March 31, 2015 (in thousands)

2015 2015 2014 Budget Actual Actual

Grants $ 124,540 $ 74,021 $ 93,598 Supplies & Services 9,573 7,043 6,086 Salaries, Wages & Employee Benefits 6,972 6,245 5,342 Amortization of Tangible Capital Assets 375 269 223 Loss on Disposal of Tangible Capital Assets - - 24

$ 141,460 $ 87,578 $105,273

2014-15 ANNUAL REPORT 35 ALBERTA INNOVATES - HEALTH SOLUTIONS Schedule 2 Salary and Benefits Disclosure For the Year Ended March 31, 2015 (in thousands)

2015 2014 Other Other Non-Cash Base Salary Cash Benefits (1) Benefits (2) (3) Total Total Chair of the Board $ - $ - $ - $ - $ 0 Board Members - 25 - 23 26 Chief Executive Officer (4) 340 - 46 386 414 Chief Partnership Officer (5) 258 - 55 313 279 Executive/Vice Presidents: Vice President - Corporate Services (6) 192 - 32 224 133 Vice President – Initiatives and Innovations (7) 171 - 43 214 51 Vice President – Provincial Platforms & SPOR (8) 63 - 19 82 - Strategic Advisor, CEO (9) 76 - 27 103 -

(1) Base salary includes regular salary. (2) Other cash benefits include earnings such as honoraria. (3) Other non-cash benefits include employer’s share of all employee benefits and contributions or payments made on behalf of employees including pension, supplementary retirement plan, health care, dental coverage, group life insurance, short and long term disability plans and professional memberships.

(4) On March 5, 2015 the Chief Partnership Officer was named interim Chief Executive Officer after the Chief Executive Office passed away.

(5) The Chief Operating Officer position was reclassified as Chief Partnership Officer in the fiscal year.

(6) The Vice President – Corporate Services position was vacant from March 15, 2013 to August 12, 2013.

(7) The Vice President – Health Technologies position was reclassified as Vice President – Initiatives and Innovations in the fiscal year.

(8) The Vice President – Provincial Platforms & SPOR is a new position that was filled on January 5, 2015.

(9) The Strategic Advisor, CEO is a new position that was filled on July 1, 2014.

36 ALBERTA INNOVATES – HEALTH SOLUTIONS ALBERTA INNOVATES - HEALTH SOLUTIONS Schedule 3 Related Party Transactions For the Year Ended March 31, 2015

Related parties are those entities consolidated or accounted for on a modified equity basis in the Government of Alberta's financial statements. Related parties also include key management personnel in the corporation. The corporation and its employees paid of collected certain taxes and fees set by regulation for premiums, licenses and other charges. These amounts were incurred in the normal course of business, reflect changes applicable to all users, and have been excluded from this Schedule.

The Corporation had the following transactions with related parties which are recorded on the Consolidated Statement of Operations and the Consolidated Statement of Financial Position at the amount of consideration agreed upon between the related parties.

(in thousands) Other Entities Outside of the Entities in the Ministry Ministry 2015 2014 2015 2014 Revenues Grants $ 97,113 $ 100,363 $ 819 $ - Other Revenue 156 71 7 4 $ 97,269 $ 100,434 $ 826 $ 4 Expenses – Directly Incurred Grants $ 3,062 $ 4,085 $ 69,063 $ 87,309 Other Services 192 58 692 867 $ 3,254 $ 4,143 $ 69,755 $ 88,176

Receivables from $ 45 $ 6,845 $ 524 $ 1,074

Payables to $ 153 $ 549 $ 7,883 $ 9,860

Deferred Revenue $ 27,004 $ 17,208 $ 2,931 $ 2,750

Contractual obligations $ 6,375 $ 6,237 $ 172,719 $ 192,799

2014-15 ANNUAL REPORT 37 ALBERTA INNOVATES - HEALTH SOLUTIONS Schedule 4 Budget For the Year Ended March 31, 2015

Original Budget Reclassifications Budget (in thousands) Revenues

Government Transfers Government of Alberta Grants $ 101,794 $ - $ 101,794 Partnership Revenue 4,797 - 4,797 Other Revenue (1) 1,434 (450) 984 Investment Income (1) - 450 450 108,025 - 108,025

Expenses (2)

Strategic Investment 73,154 (3,845) 69,309 Platforms for Success 16,123 2,700 18,823 Relationship Development 16,817 (630) 16,187 Impact Evaluation and Acceleration 1,850 425 2,275 Building Capacity 12,500 1,350 13,850 Emerging Opportunities 9,750 - 9,750 Operating / Administrative Costs 11,266 - 11,266 141,460 - 141,460

Annual operating surplus (deficit) $ (33,435) $ - $ (33,435)

(1) Interest Income was included in Other Revenue and has been reclassified to Investment Income. (2) ACPLF expenses reallocated to other key initiatives.

38 ALBERTA INNOVATES – HEALTH SOLUTIONS APPENDIX A: AIHS FUNDING AWARDS

HEALTH RESEARCH & INNOVATION SUPPORT

Collaborative Research and Innovation Opportunities (CRIO) funding suite

We support collaborative research in priority areas for CRIO – Cancer Prevention Research Alberta that engages knowledge-/end-users, produces Opportunity (CPRO) new knowledge, and helps translate knowledge to Enables a group of interdisciplinary individuals improve health and the healthcare system. working in cancer prevention research to use a collaborative approach in the creation of new CRIO Projects knowledge in cancer prevention and screening Allows a small group of interdisciplinary and moving knowledge and evidence into collaborators (minimum three) to come together use in the health system, in communities and with knowledge- and/or end-users to complete workplaces and in the daily lives of Albertans. a defined health research project with defined Maximum of 5 years. Funding level will vary deliverables. Up to $250,000 per year for up to depending upon research scope and amount 3 years. applied for (Level 1, 2 or 3):

CRIO Programs • Level 1 (up to $250,000 per year) • Level 2 (up to $500,000 per year) Enables a group of interdisciplinary collaborators • Level 3 (up to $1,000,000 per year) (three or more) who may already work together to focus on a complex program of health research and CRIO – Population Resiliency innovation that addresses health research needs, Enables a group of interdisciplinary collaborators gaps or opportunities. The research program must to focus on either (or both) of two areas of engage knowledge- and/or end-users to encourage population resiliency: aboriginal populations uptake of evidence and must be aligned to priority and child and youth. Using a collaborative areas of health for Albertans. Up to $500,000 per approach to the production of new knowledge, year for 5 years. coupled with the translation of research findings CRIO Teams to knowledge- or end-users for impact on the health of Albertans and/or the health system. Enables a large, interdisciplinary team or network Award funding will vary depending upon the of researchers with national or international stature level of research being applied for (Project, to tackle health issues involving many stakeholder Program or Team). groups. The team must have an experienced leader identified. The research activities must engage knowledge- and/or end-users to encourage uptake of evidence and must be aligned to priority areas of health for Albertans. Up to $1,000,000 per year for up to 5 years.

2014-15 ANNUAL REPORT 39 Partnership for Research and Innovation in the Translational Health Chairs Program Health System (PRIHS) A partnership with Alberta’s Comprehensive Our partnership with Alberta Health Services Academic and Research Institutions to recruit supports networks of health researchers and clinical translational health leadership in priority areas practitioners that can identify sustainable solutions to improve health and the health system. From to improve overall quality of care and value for $250,000 up to $600,000 per year for 7 years. money in the health system. Prior to 2015 awards were for up to a maximum of $250,000 per year, for Knowledge Exchange Grants up to 3 years. In 2015, no maximum award amount was set. We support the uptake, adoption and use of evidence created in Alberta and abroad to improve health and Industry Partnered Translational Fund the healthcare system.

Our industry partnerships support research and Community Engagement and Conference innovation in shared priority areas that show Grant: Supports a broad spectrum of activities a strong likelihood of technology transfer and that promote collaboration and networking in the commercialization into products, tools, therapies area of health research and innovation between and services to address needs in the health system. community groups, individuals, research groups, academic institutions, and organizations in Alberta Alberta/Novartis Translational Research Fund: and beyond. Up to $10,000. a partnership with Novartis Pharmaceuticals Canada Inc. (Novartis) and the Government Knowledge-to-Action Grant: Supports the of Alberta to catalyze the development of uptake of research evidence into health policy, innovations in health that support the interests practice and commercial development of products; and priorities of Alberta, Novartis and their and helps to build the growing body of evidence partners. Up to a maximum of $100,000 per year, for the most effective ways to approach knowledge for up to 3 years. translation. Up to a $25,000 for up to 1 year.

Alberta/Pfizer Translational Research Fund: Visiting Professorships: Supports visits to a partnership with Pfizer Canada Inc., Western Alberta by internationally recognized experts Economic Diversification (WD) Canada, and with distinguished careers who will contribute to Alberta’s Innovation and Advanced Education trainee education, support research progression, ministry to support research and innovations assist planning or launching of new research, in shared priority areas that show promise of and/or the evaluation of AIHS funded programs. commercial development into new products and Funding amount determined at time of request. services for improving health and addressing No set deadline. Due three months prior to needs in the health system. Up to $200,000 for proposed visit. up to a maximum of 18 months.

40 ALBERTA INNOVATES – HEALTH SOLUTIONS Visiting Scientists: Supports visits to Alberta Postgraduate Fellowships: Provides funding by leading health scientists or visits of Alberta for individuals with a PhD and/or professional scientists to other major research centres to enable health degree (without clinical accreditation in our health researchers to learn new approaches, Canada) who have a post-doctoral appointment knowledge, technology expertise and/or concepts at an Alberta university in a health professional or to enhance the provincial health research and health related program. Provides $50,000 per year, innovation environment. Funding amount and a research and career development allowance determined at time of request. Term from one of $5,000 per year for up to 3 years. month to 12 months. AIHS Cy Frank Fellowship: Impact Assessment: Legacy Funding Opportunities Provides funding for individuals with a PhD to pursue training in impact assessment in the field of Now closed to entry. Provided multi-year funding health research and innovation at AIHS. $70,000 for highly qualified researchers in undefined, broad per year for up to 3 years. research areas. Funding opportunities included: Interdisciplinary Teams Grants (ITGs), Alberta Clinician Researcher Training Cancer Grants, and Independent Investigator Awards. We are helping to meet the need for clinician scientists: individuals with medical training and TRAINEE SUPPORT research experience who develop research questions encountered in practice and translate their findings Graduate Studentships & Postgraduate into care. Our funding enables the training of Fellowships clinician scientists who split their time between clinical training or practice and research. We provide opportunities that support trainees in gaining broad experience in the health research MD-PhD Studentship: Provides support for environment to help them succeed in launching individuals pursuing combined MD-PhD degrees careers in academia, industry, government or at an Alberta university. Provides $30,000 per year, elsewhere. and a research and career development allowance of $2,000 per year for up to 6 years. Graduate Studentships: Provides funding for individuals enrolled in a thesis-based Master’s or Clinician Fellowship: Provides support for PhD program in a health-related research area at individuals who have clinical credentials in Canada an Alberta university. Provides $30,000 stipend to pursue graduate and postgraduate research in and a research and career development allowance a health professional or health-related program in of $2,000 per year for up to 4 years (maximum Alberta. Provides $70,000 per year, and a research of 2 years support towards a Master’s degree). and career development allowance of $5,000 per PLUS option provides up to one year of additional year for up to 3 years. support so that trainees can work in a non-research or different research environment.

2014-15 ANNUAL REPORT 41 Undergraduate & High School AIHS/Mitacs Health Pilot Partnerships

Our funding provides hands-on learning experiences We work with partners to provide internships in health research during the summer months for that give researchers-in-training community- young people considering formal research training based experiences that enable them to apply their and/or a career in the health research. knowledge to real-world health-related research challenges. $15,000 for 4 months (10,000 for HYRS: Heritage Youth Researcher Summer intern, $5,000 for project-related expenses); double Program: Provides an opportunity for exceptional internships possible. Grade 11 students to gain a direct experience of health research at an Alberta university for Legacy Training Awards six weeks in the summer. $2,000 (approximate figure) for 6 weeks. Stipend only. NOTE: Now closed. Alberta Innovates - Health Solutions Program moving from AIHS August 31, 2015 (AIHS) introduced new programs for Training and Early Career Development in 2012. The former Summer Studentships: Provides opportunities programs were awarded prior to July 1, 2012 and for students with exceptional academic standing governed under the previous guidelines. and who are registered in an undergraduate program to participate in health research in Alberta during the summer. $1,400 per month; stipend only; minimum of 2 months to a maximum of 4 months, during the period of May to August.

Media Fellowships

We work with partners to provide internships in media settings that give students the opportunity to learn and apply health science communication skills. Stipend provided is in line with interns with CBC Radio.

42 ALBERTA INNOVATES – HEALTH SOLUTIONS APPENDIX B: CURRENTLY FUNDED PROJECTS & PEOPLE (as of May 1, 2015)

CRIO PROJECTS Evaluating the Impact of Alberta Health System Changes on Outcomes in General Internal Medicine Treatment of Cholesterol-dependent Pulmonary Surfactant Finlay A. McAlister, University of Alberta Dysfunction Ann Colbourne, Alberta Health Services Matthias Amrein, University of Calgary Stafford Dean, Alberta Health Services Brent W. Winston, University of Calgary Bioprocess Production of Skin Derived Precursor (SKP) Autologous Adult Dermal Stem Cell Transplantation to Schwann Cells as Autologous Cell Therapy for Nerve and Improve Function of Split Thickness Skin Grafts Spinal Cord Repair Jeffrey A. Biernaskie, University of Calgary Rajiv Midha, University of Calgary Vincent Gabriel, University of Calgary Michael S. Kallos, University of Calgary

Towards Personalized Medicine: Novel Approaches The Human Explanted Heart Program (HELP) at the to Prognosis and Therapy of Genetically Determined Mazankowski Alberta Heart Institute: A Translational Arrhythmias Bridge for Cardiovascular Medicine Brenda Gerull, University of Calgary Gavin Y. Oudit, University of Alberta Henry J. Duff, University of Calgary Sui R. (Wayne) Chen, University of Calgary A Mechanistic Investigation of Behavioral Co-morbidity in Chronic Inflammatory Disorders A Sensorimotor Contingency-based Musical Walking Quentin J. Pittman, University of Calgary Program to Promote Healthy Living and Functional Bradley J. Kerr, University of Alberta Recovery for People Living with Parkinsons Disease Keith A. Sharkey, University of Calgary Bin Hu, University of Calgary Neurosteroids as Biomarkers and Therapies for Multiple The Alberta Perinatal Stroke Project Sclerosis (MS) C. Adam Kirton, University of Calgary Christopher N. Power, University of Alberta Jerome Y. Yager, University of Alberta Glen B. Baker, University of Alberta John Andersen, University of Alberta Gregg Blevins, University of Alberta

Deep Brain Stimulation for Treatment Resistant Depressive Modulation of Stem Cell Pluripotency and Differentiation Disorders via Mechanotransduction in Bioreactors Zelma H. T. Kiss, University of Calgary Derrick E. Rancourt, University of Calgary Rajamannar Ramasubbu, University of Calgary Production of Adult Synovial Stem Cell Based Tissue Invariant NKT Cells as the Link between Brain Injury and Engineered Constructs to Clinically Treat Cartilage Defects Susceptibility to Infections Arindom Sen, University of Calgary Paul Kubes, University of Calgary David A. Hart, University of Calgary Neil A. Duncan, University of Calgary

2014-15 ANNUAL REPORT 43 Implementation and Validation of the “5As Framework of CRIO PROGRAMS Obesity Management” in Primary Care Arya M. Sharma, University of Alberta Promoting Appropriate Maternal Body Weight in Pregnancy Denise Campbell-Scherer, University of Alberta and Postpartum through Healthy Dietary Intake Sheri Fielding, Primary Care Network Rhonda C. Bell, University of Alberta Linda J. McCargar, University of Alberta Sustaining Transfers through Affordable Research Paula J. Robson, Alberta Health Services Translation (START): Knowledge Translation Interventions to Support the Uptake of Innovations in Alberta Program in Youth Sport and Recreational Injury Continuing Care Settings Prevention Susan E. Slaughter, University of Alberta Carolyn A. Emery, University of Calgary Allyson Jones, University of Alberta Brent E. Hagel, University of Calgary Carole A. Estabrooks, University of Alberta Adrian Wagg, University of Alberta Addressing Community Concerns about Health Risks from Misha Eliasziw, Tufts University H.pylori Infection

How does Management of Chronic Obstructive Pulmonary Karen J. Goodman, University of Alberta Disease Hospitalizations affect Patient-centred Health Outcomes and Cardiovascular Risk? Advance Care Planning and Goals of Care Alberta: A Population Based Knowledge Translation Intervention Michael K. Stickland, University of Alberta Study Richard Leigh, University of Calgary Mohit Bhutani, University of Alberta Neil A. Hagen, University of Calgary Konrad P. Fassbender, University of Alberta The Development of Highly Efficient and Specific Multi- Jessica E. Simon, Alberta Health Services modal Contrast Agents for Breast Cancer Diagnosis Pharmacokinetic and Radiation Dosimetry Evaluations * Boguslaw Tomanek, University of Calgary of IAZA and its Translation in Molecular Theranostic B. Gino Fallone, University of Alberta Management of Solid Tumors

Lactoferrin, Lysozyme and Lipocalins; from Natural Anti- Michael Weinfeld, University of Alberta infective Eye-drops to Treating Sepsis? Piyush Kumar, University of Alberta Naresh Jha, University of Alberta Hans J. Vogel, University of Calgary John R. Mercer, University of Alberta Alexander (Sandy) McEwan, University of Alberta A New Molecular Platform for Studying Parkinson’s Hans-Sonke F. Jans, University of Alberta Disease: Molecular Mechanisms and Therapeutic Targets Michael Woodside, University of Alberta An Interdisciplinary Program to Develop Therapeutic Nils O. Petersen, University of Alberta Interventions for Peroxisome Disorders Richard A. Rachubinski, University of Alberta Intensive Motor Training After Perinatal Stroke to Andrew J. Simmonds, University of Alberta Enhance Walking Nancy Braverman, McGill University Jaynie F. Yang, University of Alberta Monica A. Gorassini, University of Alberta

* ACPLF

44 ALBERTA INNOVATES – HEALTH SOLUTIONS CRIO TEAMS COHORT 1 CRIO TEAMS COHORT 2 MARCH 2013 APRIL 2014

Development of a Clinical Linac-MR System for Image- Alberta Provincial Pediatric EnTeric Infection TEam guided Radiation Therapy (APPETITE): Epidemiology, Emerging Organisms, and Economics B. Gino Fallone, University of Alberta Stephen Freedman, University of Calgary W21C: Interdisciplinary Research and Innovation for Bonita E. Lee, University of Alberta Health System Quality and Safety Marie Louie, University of Calgary Xiaoli L. Pang, University of Alberta William A. Ghali, University of Calgary Henry T. Stelfox, University of Calgary Improving the Efficient and Equitable Care of Patients with John M. Conly, Foothills Hospital Chronic Medical Conditions: Interdisciplinary Chronic Disease Collaboration (ICDC) Development of a Vaccine Against the Hepatitis C Virus (HCV) and Demonstration of Efficacy in Intravenous Drug Brenda Hemmelgarn, University of Calgary Users Braden J. Manns, University of Calgary Marcello A. Tonelli, University of Alberta Michael Houghton, University of Alberta

D. Lorne Tyrrell, University of Alberta Quality Improvement - Clinical Research (QuICR): Alberta

Stroke Team Alberta Ocular Gene Therapy Team Michael D. Hill, University of Calgary Ian M. MacDonald, University of Alberta Ashfaq Shuaib, University of Alberta Tania Bubela, University of Alberta Andrew M. Demchuk, University of Calgary

Thomas Jeerakathil, University of Alberta Leading Clinical Trials in Islet and Stem Cell Transplantation, Restoration of Self-tolerance and Beta Cell Return on Investments in Innovative Interventions that Regeneration - Solving the Supply and Survival Problem in Promote Healthy Eating and Active Living among Children Type 1 Diabetes Veugelers, Paul J. A. M. James Shapiro, University of Alberta University of Alberta Peter E. Light, University of Alberta Ohinmaa, Arto E. Lori West, University of Alberta University of Alberta

Metabolomic Devices for Companion Diagnostics and Medicines for Remyelination in Multiple Sclerosis: The Next Personalized Medicine Frontier David S. Wishart, University of Alberta Voon Wee Yong, University of Calgary Luanne M. Metz, University of Calgary

2014-15 ANNUAL REPORT 45 CANCER PREVENTION RESEARCH Interactions of Targeted Anticancer Drugs with Nucleoside OPPORTUNITY (CPRO) - 1 Transporters and the Roles of Nucleoside Binding Proteins in Targeted Anticancer Drug Toxicities Novel Biomarkers and Therapeutics for Intestinal Michael B. Sawyer, University of Alberta Inflammation and Colorectal Cancer James D. Young,University of Alberta Shairaz Baksh, University of Alberta Levinus A. Dieleman, University of Alberta Attitudes Towards Cancer in Arctic Communities & Carlos A. Velazquez, University of Alberta Examining Uptake of Screening Services: The ACCESS Project Marius Sudol, Geisinger Health System Sangita Sharma, University of Alberta Carolyn C. Gotay, University of British Columbia PIK3CA Mutation and Associated Pathway Activation Status Fariba Kolahdooz, University of Alberta and Survival in Patients with Cervical Cancer: Quantifying Mohammadreza Pakseresht, University of Alberta the Risk and Testing the Solution Corinne Doll, University of Calgary Toward Improved Outcomes of Antithymocyte Globulin- Susan P. Lees-Miller, University of Calgary conditioned Hematopoietic Cell Transplantation Martin Koebel, University of Calgary Jan Storek, University of Calgary Prafull Ghatage, University of Calgary Don Morris, University of Calgary Faisal M. Khan, University of Calgary Non-invasive Staging of Prostate Cancer: Translating

Biomarkers to Clinical Practice A Semi-automated Surgeon’s Assistant for Prostate John D. Lewis, University of Alberta Brachytherapy Ronald B. Moore, University of Alberta Mahdi Tavakoli, University of Alberta

Ronald S. Sloboda, University of Alberta Immunotherapy for Cancer - Repurposing Targeted Nawaid H. Usmani, University of Alberta Therapeutics with Oncolytic Viruses

Don Morris, University of Calgary Specialty SONAR (Study Of Natural health products Adverse Paul P. Beaudry, University of Calgary Reactions) Focus on Cancer Subjects Doug Mahoney, University of Calgary Sunita Vohra, University of Alberta

Sunil Desai, University of Alberta Improving the Prevention, Diagnosis, and Treatment of Peter Venner, University of Alberta Post-transplant Lymphoproliferative Disorders after Solid Organ Transplantation using Peripheral Blood and Tissue Targeting the STAT3 Signalling Pathway in Glioblastoma Biomarkers Samuel Weiss, University of Calgary Jutta K. Preiksaitis, University of Alberta H. Artee Luchman, University of Calgary Raymond K. Lai, University of Alberta Gregory Cairncross, University of Calgary Anthea C. Peters, University of Alberta Patrick T. Gunning, University of Toronto Upton D. Allen, University of Toronto

Development of New Imaging Agents and Therapeutic Platforms for Improving Clinical Outcomes for Brain Tumour Patients Stephen M. Robbins, University of Calgary Donna L. Senger, University of Calgary Warren Chan, University of Toronto Sheila Singh, McMaster University

46 ALBERTA INNOVATES – HEALTH SOLUTIONS CANCER PREVENTION RESEARCH CRIO POPULATION RESILIENCY - OPPORTUNITY (CPRO) - 2 PROGRAM

Innovative Diagnostics to Improve the Management of Alberta Resilient Communities Research Project: Engaging Urothelial Carcinoma Children and Youth in Community Resilience Post-flood in Matthew Eric Hyndman, University of Calgary Southern Alberta Don Morris, University of Calgary Julie Drolet, University of Calgary Robin S. Cox, Royal Roads College Preclinical Theranostic Evaluations of Solid Tumors using Caroline McDonald-Harker, Mount Royal College FAZA and its Prodrugs (TEST-F): A Hypoxia-selective ‘Bench to Bedside’ Innovation for Cancer Management Michael Weinfeld, University of Alberta CRIO POPULATION RESILIENCY - Hans-Sonke F. Jans, University of Alberta TEAM Sandy McEwan, University of Alberta David Murray, University of Alberta Prediction and Understanding of Resilience in Alberta Piyush Kumar, University of Alberta Families: Longitudinal Study of Disaster Responses (PURLS) Novel Nanoparticulate STAT3 Inhibitors for Treating Dawn Kingston, University of Alberta Multiple Myeloma Anrew Greenshaw, University of Alberta Raymond K. Lai, University of Alberta Sheila McDonald, Alberta Health Services Quincy S. Chu, University of Alberta Suzanne Tough, University of Calgary Afsaneh Lavasanifar, University of Alberta Christopher P. Venner, University of Alberta INTERDISCIPLINARY TEAM GRANT Developing and Testing a New Treatment for Oral Squamous Cell Carcinoma AHFMR Interdisciplinary Team Grant on Understanding and Treating Diastolic Heart Failure: Novel Mechanisms, Karl T. Riabowol, University of Calgary Diagnostics and Potential Therapeutics Joseph C. Dort, University of Calgary Don Morris, University of Calgary Jason Dyck, University of Alberta Todd Anderson, University of Calgary Activating Microglia and Macrophages to Suppress Brain Tumor-initiating Cells Voon Wee Yong, University of Calgary Jeffery F. Dunn, University of Calgary John J. Kelly, University of Calgary

2014-15 ANNUAL REPORT 47 PARTNERSHIP FOR RESEARCH AND INNOVATION IN THE HEALTH SYSTEM (PRIHS)

STRATEGIC CLINICAL NETWORK: CRITICAL CARE STRATEGIC CLINICAL NETWORK: EMERGENCY Identifying and Evaluating Intensive Care Unit Capacity Improving the Stewardship of Diagnostic Imaging Resources Strain in Alberta in Alberta Emergency Departments Sean Bagshaw, University of Alberta Eddy S. Lang, University of Calgary Henry T. Stelfox, University of Calgary James Andruchow, University of Calgary Michael J. Bullard, University of Alberta STRATEGIC CLINICAL NETWORK: CARDIOVASCULAR Derek J. Emery, University of Alberta & STROKE Brian Holroyd, University of Alberta Efficient / Effective Delivery & Follow-up of Cardiovascular Andrew D. McRae, University of Calgary Implantable Electrical Devices in Alberta: Performance Brian H. Rowe, University of Alberta Evaluation & Rhythm Follow-up Optimization with Remote Robert J. Sevick, University of Calgary Monitoring (PERFORM) Collaborative Project

Derek V. Exner, University of Calgary STRATEGIC CLINICAL NETWORK: BONE & JOINT HEALTH Sandeep Aggarwal, University of Calgary Optimizing Centralized Intake to Improve Arthritis Care for Brian Buck, University of Alberta Albertans Andrew M. Demchuk, University of Calgary Deborah A. Marshall, University of Calgary Sajad Gulamhusein, University of Alberta Linda Woodhouse, University of Alberta Colleen M. Norris, University of Alberta Roopinder K. Sandhu, University of Alberta STRATEGIC CLINICAL NETWORK: CANCER Stephen B. Wilton, University of Calgary Rectal Cancer Care Clinical Pathway

STRATEGIC CLINICAL NETWORK: DIABETES, OBESITY Todd P. McMullen, Alberta Health Services & NUTRITION Don Buie, University of Calgary Care and Rehabilitation for Patients with Severe Obesity in Neil A. Hagen, University of Calgary Alberta’s Tertiary Care Settings Mary Forhan, University of Alberta STRATEGIC CLINICAL NETWORK: CRITICAL NETWORK Jeffrey A. Johnson, University of Alberta Reassessing Practices in the Daily Care of Critically Ill Arya M. Sharma, University of Alberta Patients: Building Capacity and Methodology to Identify & Close Evidence-care Gaps STRATEGIC CLINICAL NETWORK: SURGERY Henry T. Stelfox, University of Calgary Enhancing Patients’ Recovery After Surgery (ERAS): Strategy Sean Bagshaw, University of Alberta to Transform Care and Maximize Value Leah M. Gramlich, Alberta Health Services STRATEGIC CLINICAL NETWORK: BONE & JOINT HEALTH Gregg S. Nelson, University of Calgary SpineAccess Alberta: An Innovative Health Service Delivery and Spine Management Model STRATEGIC CLINICAL NETWORK: SENIORS’ HEALTH Linda Woodhouse, University of Alberta Optimizing Seniors Surgical Care - The Elder Friendly Gregory N. Kawchuk, University of Alberta Surgical Unit Leah Phillips, Alberta Health Services Rachel G. Khadaroo, University of Alberta Fiona Clement, University of Calgary Jayna Holroyd-Leduc, Alberta Health Services Raj Padwal, University of Alberta Adrian Wagg, University of Alberta

48 ALBERTA INNOVATES – HEALTH SOLUTIONS ALBERTA/PFIZER TRANSLATIONAL ALBERTA/PFIZER TRANSLATIONAL RESEARCH FUND 1 RESEARCH FUND 2

MR Quantitative Iron Imaging in Alzheimer’s Disease and Novel Multifunctional Small Molecules for the Treatment of Dementia Atrial Fibrillation Richard Frayne, University of Calgary Jason Dyck, University of Alberta Eric E. Smith Peter Light, University of Alberta

Predictive Biomarkers of Taxane Response Managing Cardiovascular Contractile Abnormalities with a Novel Inhibitor of Zipper-interacting Protein Kinase Ing Swie Goping, University of Alberta Judith C. Hugh Justin MacDonald, University of Calgary John R. Mackey Timothy Haystead, Duke University Todd P. McMullen Bijoy Menon, University of Calgary

Development and Validation for a Novel Rescue Therapy for A Monoclonal Antibody to Restore Radioiodine Sensitivity Severe Asthma and Decrease Tumor Burden in Metastatic Papillary Thyroid Carcinoma Francis H. Green, University of Calgary Richard Leigh Todd McMullen, University of Alberta John Mackey, University of Alberta Development of Disease Modifying Therapies for Huntington’s Disease Targeting PI3 Kinase Isoforms to Inhibit Tumor Neovascularization Simonetta Sipione, University of Alberta Allan Murray, University of Alberta Ronald Moore, University of Alberta

N-acetylglucosamine Analogs that Promote Remyelination and Reduce Detrimental Inflammation: Novel Therapeutics for Multiple Benefits in Multiple Sclerosis Voon Wee Yong, University of Calgary Chang-Chun Ling, University of Calgary

Regulation of T-type Calcium Channel Expression - A Novel Strategy for the Treatment of Pain Gerald Zamponi, University of Calgary

2014-15 ANNUAL REPORT 49 KNOWLEDGE TO ACTION A Knowledge Translation Pilot Intervention in Community Pharmacies using the PARiHS Framework Improving Knowledge Regarding Pregnancy and Ross T. Tsuyuki, University of Alberta Inflammatory Bowel Disease Richard N. Fedorak, University of Alberta Increasing Usability of Administrative Healthcare Data Vivian W. Huang, University of Alberta Through a Web-based Tool for Systematic Exploration of Medical Coding Ontologies Outcomes in Child Health: A Qualitative Study of Social Samuel Wiebe, University of Calgary Media for Stakeholder Engagement Lisa A. Hartling, University of Alberta Ricardo M. Fernandes, University of Lisbon TRANSLATIONAL HEALTH CHAIRS Michele Hamm, University of Alberta PROGRAM Amy Plint, University of Ottawa Brian H. Rowe, University of Alberta Nicholas Ashbolt Shannon D. Scott, University of Alberta University of Alberta, School of Public Health Cheryl L. Currie Improving Care Adults with Parkinson’s Disease and Dementia Complicated by Comorbid Depression and Anxiety University of Lethbridge, Health Sciences Jayna Holroyd-Leduc, University of Calgary Lee A. Green Zahra S. Goodarzi, University of Calgary University of Alberta, Medicine & Dentistry Ian Lewis Utility of a Clinical Diagnostic Algorithm to Reduce CT University of Calgary, Science Imaging for ED Patients with Suspected Renal Colic Lynne-Marie Postovit Grant Innes, University of Calgary University of Alberta, Medicine & Dentistry James Andruchow, University of Calgary

Building Capacity for Evidence-informed Decision-making VISITING SCIENTIST Around the Introduction of New Technologies: Rolling Out the “Evidence Decision Support Program” to New Strategic HOST: Clinical Network Vivian K. Mushahwar Paule M. Poulin, University of Calgary University of Alberta Luke Rudmik, University of Calgary CANDIDATE: Trevor Schuler, University of Alberta Eberhard E. Fetz

Physiology & Biophysics, University of Washington Metabolomics of Airway Diseases: Improving Management in Seattle, Washington the Emergency Department

Brian Rowe, University of Alberta Darryl Adamko, University of Saskatchewan

Retiring Minds Want to Know: Understanding Seniors Knowledge About Research Practices and its Affect on Their Attitude Towards Participation Rachel Syme, University of Calgary Suzanne Vorvis, Alberta Health Services

50 ALBERTA INNOVATES – HEALTH SOLUTIONS TRAINEE SUPPORT

Graduate Studentships

Liane Babes, University of Calgary Anne-Francoise J. P. Close, University of Alberta ACPLF - Graduate Studentship Graduate Studentship Denise E. Bustard, University of Calgary Stephen A. Cochrane, University of Alberta ACPLF - Graduate Studentship Graduate Studentship Juliana S. Capitanio, University of Alberta Subhash K. Das, University of Alberta ACPLF - Graduate Studentship Graduate Studentship Douglas E. Friesen, University of Alberta Chelsea L. Davidson, University of Alberta ACPLF - Graduate Studentship Graduate Studentship Shyam Madhusudan Garg, University of Alberta Bradley D. Day, University of Calgary ACPLF - Graduate Studentship Graduate Studentship Seyyed M. Kazemi-Bajestani, University of Alberta Sutherland T. A. Dube, University of Lethbridge ACPLF - Graduate Studentship Graduate Studentship Brent A. McLean, University of Alberta Shane E.A. Eaton, University of Calgary ACPLF - Graduate Studentship Graduate Studentship Rebecca J. Mercier, University of Alberta Kristofor K. Ellestad, University of Alberta ACPLF - Graduate Studentship Graduate Studentship Xiaobin Mo, University of Alberta Ahmed A. El-Sherbeni, University of Alberta ACPLF - Graduate Studentship Graduate Studentship Hali A. Morrison, University of Alberta Natasha Fillmore, University of Alberta ACPLF - Graduate Studentship Graduate Studentship Manoj B. Parmar, University of Alberta Dominic P. Golec, University of Alberta ACPLF - Graduate Studentship Graduate Studentship Kaitlyn M. Towle, University of Alberta Ahmed M. Hashad, University of Calgary ACPLF - Graduate Studentship Graduate Studentship Juliana Valencia Serna, University of Alberta Ammar Hassanzadeh Keshteli, University of Alberta ACPLF - Graduate Studentship Graduate Studentship Ganesh Venkatraman, University of Alberta Roopa Hebbandi Nanjundappa, University of Calgary ACPLF - Graduate Studentship Graduate Studentship Ahmed S. Abdelfattah, University of Alberta Brett T. Himmler, University of Lethbridge Graduate Studentship Graduate Studentship Christina A. Ahlstrom, University of Calgary Veronika Kiryanova, University of Calgary Graduate Studentship Graduate Studentship Roger A. Ashmus, University of Alberta Christen M. Klinger, University of Alberta Graduate Studentship Graduate Studentship Jillian L. S. Avis, University of Alberta Dylan R.J. Kobsar, University of Calgary Graduate Studentship Graduate Studentship Briana D. Cassetta, University of Calgary Ranjan Kumar, University of Calgary Graduate Studentship Graduate Studentship Patrick Ciechanski, University of Calgary Patricia Leighton, University of Alberta Graduate Studentship Graduate Studentship

2014-15 ANNUAL REPORT 51 Irene Liu, University of Calgary Brittney N.V. Scott, University of Calgary Graduate Studentship Graduate Studentship Yingjie Liu, University of Calgary Simon A. Sharples, University of Calgary Graduate Studentship Graduate Studentship Kelsey D. Lucyk, University of Calgary Michael J. Spilka, University of Calgary Graduate Studentship Graduate Studentship Danielle C. Lynch, University of Calgary Erin L. Stephenson, University of Calgary Graduate Studentship Graduate Studentship Dun Mao, University of Lethbridge Alexander Y.W. Suen, University of Alberta Graduate Studentship Graduate Studentship Shaun M.K. McKinnie, University of Alberta Ho-Yan Sun, University of Alberta Graduate Studentship Graduate Studentship Sheldon D. Michaelson, University of Alberta Jennifer L. Swan, University of Calgary Graduate Studentship Graduate Studentship Luis C. Morales, University of Alberta Charmaine L. Thomas, University of Calgary Graduate Studentship Graduate Studentship Michael J. Mousseau, University of Calgary Amirali Toossi, University of Alberta Graduate Studentship Graduate Studentship Myung-Chul (Sam) Noh, University of Alberta Scott G. Travis, University of Alberta Graduate Studentship Graduate Studentship Van A. Ortega, University of Alberta Sarah C. Treit, University of Alberta Graduate Studentship Graduate Studentship Marc A. Parsons, University of Alberta Daniel Unterweger, University of Alberta Graduate Studentship Graduate Studentship Joshua Pemberton, University of Alberta Haris M. Vaid, University of Calgary Graduate Studentship Graduate Studentship Jennifer L. Prentice, University of Calgary Isabelle A. Vallerand, University of Calgary Graduate Studentship Graduate Studentship Leanne Quigley, University of Calgary Marie Betsy Varughese, University of Alberta Graduate Studentship Graduate Studentship Joshua A. Rash, University of Calgary Robin L. Walker, University of Calgary Graduate Studentship Graduate Studentship Ruksana S. Rashid, University of Calgary Qian Wang, University of Alberta Graduate Studentship Graduate Studentship James A. Rogers, University of Calgary Michele B. Wellsby, University of Calgary Graduate Studentship Graduate Studentship Codie R. Rouleau, University of Calgary Lindsey M. Westover, University of Alberta Graduate Studentship Graduate Studentship Khara M. Sauro, University of Calgary Thomas R. Whitesell, University of Calgary Graduate Studentship Graduate Studentship Sabine I. Schmelz, University of Alberta James P. Wick, University of Calgary Graduate Studentship Graduate Studentship Jonathon S. Schofield, University of Alberta Grey A. Wilkinson, University of Calgary Graduate Studentship Graduate Studentship

52 ALBERTA INNOVATES – HEALTH SOLUTIONS Dong Yan, University of Calgary Erin-Mai F. Lim, University of Calgary Graduate Studentship Studentship - Full-Time Elaine E.O. Hyshka, University of Alberta Leiah M. Luoma, University of Alberta Health Research - Full-Time Studentship Studentship - Full-Time Jillian A. Johnson, University of Calgary James Mackay, University of Alberta Health Research - Full-Time Studentship Studentship - Full-Time Jiaying Liu, University of Alberta Chelsea E. Matisz, University of Calgary Health Research - Full-Time Studentship Studentship - Full-Time Kristin R. Newman, University of Calgary Leanne Mortimer, University of Calgary Health Research - Full-Time Studentship Studentship - Full-Time Linette D. Savage, University of Calgary Heather A.S. Paul, University of Calgary Health Research - Full-Time Studentship Studentship - Full-Time Marc R. Bomhof, University of Calgary Sandra E. Pineda Sanabria, University of Alberta Studentship - Full-Time Studentship - Full-Time Sean C. Booth, University of Calgary Laura M. Reyes, University of Alberta Studentship - Full-Time Studentship - Full-Time Phillip L.W. Colmers, University of Calgary Kathleen A. Scullion, University of Calgary Studentship - Full-Time Studentship - Full-Time Michael M. DuVall, University of Calgary Sara R. Turner, University of Calgary Studentship - Full-Time Studentship - Full-Time Cara E. Ellis, University of Alberta Nicholas L. Weilinger, University of Calgary Studentship - Full-Time Studentship - Full-Time Justin G. Fedor, University of Alberta Steven D. Willows, University of Alberta Studentship - Full-Time Studentship - Full-Time Maria R. Fernando, University of Calgary Xiaowei Zhong, University of Calgary Studentship - Full-Time Studentship - Full-Time Trisha M. Finlay, University of Calgary Cameron Clark, University of Calgary Studentship - Full-Time Studentship - Mental Health Research Nichole M. Flynn, University of Calgary Jennifer D. Ference, University of Calgary Studentship - Full-Time Studentship - Mental Health Research Erin L. Garside, University of Alberta Perla A. Cota-Elizondo, Resverlogix Studentship - Full-Time Graduate Studentship - PLUS Angela M. Getz, University of Calgary Lauren E. Killip, Focal Healthcare Inc. Studentship - Full-Time Graduate Studentship - PLUS Catherine Hajmrle, University of Alberta Studentship - Full-Time Emily K. Herman, University of Alberta Studentship - Full-Time Curtis D. Hodge, University of Alberta Studentship - Full-Time Kathrin Koblinger, University of Calgary Studentship - Full-Time Gabriella Leung, University of Calgary Studentship - Full-Time

2014-15 ANNUAL REPORT 53 MD-PhD Studentship Clinician Fellows

Matthew G.K. Benesch, University of Alberta Mohammad Ali, University of Alberta ACPLF-Clinician Researcher MD-PhD Studentship ACPLF - Clinician Fellowship Lauren C. Capozzi, University of Calgary Gabriela Constantinescu, University of Alberta ACPLF-Clinician Researcher MD-PhD Studentship ACPLF - Clinician Fellowship Erin S. Degelman, University of Calgary Amy Hobbs, University of Calgary ACPLF-Clinician Researcher MD-PhD Studentship ACPLF - Clinician Fellowship Kristen I. Barton, University of Calgary Vijay Ramaswamy, The Hospital for Sick Children Clinician Researcher - MD-PhD Studentship ACPLF - Fellowship - Clinical Craig A. Beers, University of Calgary Kevin R. Boldt, University of Calgary Clinician Researcher - MD-PhD Studentship Clinician Researcher - Clinician Fellowship Brandon M. Hisey, University of Calgary David J.T. Campbell, University of Calgary Clinician Researcher - MD-PhD Studentship Clinician Researcher - Clinician Fellowship Ryan J. Leigh, University of Calgary Brea D. Chouinard, University of Alberta Clinician Researcher - MD-PhD Studentship Clinician Researcher - Clinician Fellowship Ryan T. Lewinson, University of Calgary Catherine A. Eastwood, University of Calgary Clinician Researcher - MD-PhD Studentship Clinician Researcher - Clinician Fellowship Taryn E. Ludwig, University of Calgary Meghan J. Elliott, University of Toronto Clinician Researcher - MD-PhD Studentship Clinician Researcher - Clinician Fellowship Nabeela Nathoo, University of Calgary Sonja E. Findlater, University of Calgary Clinician Researcher - MD-PhD Studentship Clinician Researcher - Clinician Fellowship Laura A. Palmer, University of Calgary Boris L. Gala Lopez, University of Alberta Clinician Researcher - MD-PhD Studentship Clinician Researcher - Clinician Fellowship Waleed M. Rahmani, University of Calgary Tamara H. Germani, University of Alberta Clinician Researcher - MD-PhD Studentship Clinician Researcher - Clinician Fellowship Amrita Roy, University of Calgary Laura Catherine Gioia, University of Alberta Clinician Researcher - MD-PhD Studentship Clinician Researcher - Clinician Fellowship James A. Cotton, University of Calgary Joey K. Grochmal, University of Calgary Studentship - MD/PhD Clinician Researcher - Clinician Fellowship Zaheed Damani, University of Calgary Vivian W. Huang, University of Alberta Studentship - MD/PhD Clinician Researcher - Clinician Fellowship Alexandra D. Frolkis, University of Calgary Colin B. Josephson, University of Calgary Studentship - MD/PhD Clinician Researcher - Clinician Fellowship Michael B. Keough, University of Calgary Mahesh P. Kate, University of Alberta Studentship - MD/PhD Clinician Researcher - Clinician Fellowship Christina S. Thornton, University of Calgary Graham Z. MacDonald, University of Calgary Studentship - MD/PhD Clinician Researcher - Clinician Fellowship Shannon E. MacDonald, University of Calgary Clinician Researcher - Clinician Fellowship Holly E. Mewhort, University of Calgary Clinician Researcher - Clinician Fellowship Karim Michail, University of Alberta Clinician Researcher - Clinician Fellowship

54 ALBERTA INNOVATES – HEALTH SOLUTIONS Kara Murias, University of Calgary Dolan Champa Saha, University of Calgary Clinician Researcher - Clinician Fellowship Fellowship - Full Time Daniel J. Niven, University of Calgary Luciana G. Macedo, University of Alberta Clinician Researcher - Clinician Fellowship Health Research - Full-Time Fellowship Joseph J. Pagano, University of Alberta Basant Abdulrahman, University of Calgary Clinician Researcher - Clinician Fellowship Postgraduate Fellowship Aylin Y. Reid, University of California, Los Angeles Misagh Alipour, University of Alberta Clinician Researcher - Clinician Fellowship Postgraduate Fellowship Derek J. Roberts, University of Calgary Anwar Anwar-Mohamed, University of Alberta Clinician Researcher - Clinician Fellowship Postgraduate Fellowship Humam Saltaji, University of Alberta Eugene Asahchop, University of Alberta Clinician Researcher - Clinician Fellowship Postgraduate Fellowship Raina Soudy, University of Alberta Hamideh Bayrampour, University of Calgary Clinician Researcher - Clinician Fellowship Postgraduate Fellowship Karen Tang, University of Calgary Jillian E. Beveridge, University of Calgary Clinician Researcher - Clinician Fellowship Postgraduate Fellowship Stephanie E. Thompson, University of Alberta Andrew V. Caprariello, University of Calgary Clinician Researcher - Clinician Fellowship Postgraduate Fellowship Daniel Yavin, University of Calgary Alison Care, University of Alberta Clinician Researcher - Clinician Fellowship Postgraduate Fellowship Beshay N.M. Zordoky, University of Alberta Matthew A. Churchward, University of Alberta Clinician Researcher - Clinician Fellowship Postgraduate Fellowship Humberto Jijon, Harvard Medical School Darren Clark, University of Calgary Fellowship - Clinical Postgraduate Fellowship Derek R. Dee, University of Alberta Postgraduate Fellowship Justin F Deniset, University of Calgary Postgraduate Fellows Postgraduate Fellowship Sambuddha Banerjee, University of Calgary Elizabeth Dogherty, University of Alberta ACPLF - Postgraduate Fellowship Postgraduate Fellowship David J. E. Bond, University of Alberta Lauren L. Drogos, University of Calgary ACPLF - Postgraduate Fellowship Postgraduate Fellowship Mohamed A. M. El Gendy, University of Alberta Jordan D. T. Engbers, University of Calgary ACPLF - Postgraduate Fellowship Postgraduate Fellowship Ruo-Xu Gu, University of Calgary Keith Fenrich, University of Alberta ACPLF - Postgraduate Fellowship Postgraduate Fellowship Shrivani Pirahas, University of Calgary Brandon L. Findlay, University of Alberta ACPLF - Postgraduate Fellowship Postgraduate Fellowship Shahzada Junaid S. Qazi, University of Calgary Christian Foerster, University of Alberta ACPLF - Postgraduate Fellowship Postgraduate Fellowship Judit Voros, University of Alberta Shelagh K. Genuis, University of Alberta ACPLF - Postgraduate Fellowship Postgraduate Fellowship Shereen M. Hamza, University of Alberta Jessica Gifford, University of Alberta Fellowship - Full Time Postgraduate Fellowship

2014-15 ANNUAL REPORT 55 Megan Gray, University of Calgary Ian M. Robertson, University of Alberta Postgraduate Fellowship Postgraduate Fellowship Matthias Hoben, University of Alberta David G. Rosenegger, University of Calgary Postgraduate Fellowship Postgraduate Fellowship Charlie Y.M. Hsu, University of Calgary Lori Anne R. Sacrey, University of Alberta Postgraduate Fellowship Postgraduate Fellowship Min Jun, University of Calgary Mohammed Abdullah Sarhan, University of Alberta Postgraduate Fellowship Postgraduate Fellowship Anand Krishnan, University of Alberta Jennifer Semrau, University of Calgary Postgraduate Fellowship Postgraduate Fellowship Tamia K. Lapointe, University of Calgary Supratik Sen Mojumdar, University of Alberta Postgraduate Fellowship Postgraduate Fellowship Joseph A. Lemire, University of Calgary Ian Smith, University of Calgary Postgraduate Fellowship Postgraduate Fellowship Aviad Levin, University of Alberta Floor Spaans, University of Alberta Postgraduate Fellowship Postgraduate Fellowship Daniel Limonta Velazquez, University of Alberta Matthew D. Spencer, University of Calgary Postgraduate Fellowship Postgraduate Fellowship Alexander W. Lohman, University of Calgary Patrick L. Stemkowski, University of Calgary Postgraduate Fellowship Postgraduate Fellowship Emilie Magaud, University of Calgary Bo Sun, University of Calgary Postgraduate Fellowship Postgraduate Fellowship Mohsen Maleki Karyak, University of Calgary Bas Gerardus Johannes Surewaard, University of Calgary Postgraduate Fellowship Postgraduate Fellowship Manmeet K. Mamik, University of Alberta Mireille V. Tittel-Elmer, University of Calgary Postgraduate Fellowship Postgraduate Fellowship Leah J. Martin, University of Alberta Cam Ha Tran, University of Calgary Postgraduate Fellowship Postgraduate Fellowship Erin L. Mazerolle, University of Calgary Channakeshava S. Umeshappa, University of Calgary Postgraduate Fellowship Postgraduate Fellowship Lindsay Naef, University of Calgary Anil Kumar Victoria Ansalem, University of Alberta Postgraduate Fellowship Postgraduate Fellowship Van A. Ngo, University of Calgary Xavier Waltz, University of Calgary Postgraduate Fellowship Postgraduate Fellowship Nirmal Parajuli, University of Alberta Anil Zechariah, University of Calgary Postgraduate Fellowship Postgraduate Fellowship Heekuk Park, University of Alberta Franz J. Zemp, University of Calgary Postgraduate Fellowship Postgraduate Fellowship Vaibhav Patel, University of Alberta Fang-Xiong Zhang, University of Calgary Postgraduate Fellowship Postgraduate Fellowship Angkoon Phinyomark, University of Calgary Agnieszka A. Zurek, University of Calgary Postgraduate Fellowship Postgraduate Fellowship Geoffrey A. Power, University of Calgary Postgraduate Fellowship

56 ALBERTA INNOVATES – HEALTH SOLUTIONS Heritage Youth Researcher Summer (HYRS) Stephanie Li, Edmonton Program Old Scona Academic High School Mentor: Mary M. Hitt UNIVERSITY OF ALBERTA Christine Lo, Grande Prairie Darya Abdolmaleki, Fort McMurray Grande Prairie Composite High School Westwood Community High School Mentor: Sarah C. Hughes Mentor: Elaine M. Leslie Lucas Mina, Edmonton Kristofer Akkerman, St Albert Holy Trinity Catholic High School St Albert Catholic High School Mentor: Thomas Simmen Mentor: Ratmir Derda Colleen Moore, St Albert Mazzen Black, Edmonton Paul Kane High School Tempo School Mentor: Peter E. Light Mentor: Gina R. Rayat Tamara Radovic, Edmonton Neha Goel, Edmonton Archbishop MacDonald Catholic High School Lillian Osborne High School Mentor: Maya Shmulevitz Mentor: John D. Lewis Aditya Sharma, Grande Prairie Rachel Goud, Edmonton Grande Prairie Composite High School Jasper Place High School Mentor: John M. Seubert Mentor: Jens Walter Andrea Tack, Edmonton Ben Hallworth, Edmonton Harry Ainlay High School Strathcona High School Mentor: Ian MacDonald Mentor: Karim Fouad Vanessa Vuong, Edmonton Tamanna Haque, Fort McMurray McNally High School Westwood Community High School Mentor: Sandra T. Davidge Mentor: Karen J. Goodman Sarah Willette, St Albert Ruicen He, Edmonton Ecole Secondaire Sainte Marguerite d’Youville Old Scona Academic High School Mentor: Lynne-Marie Postovit Mentor: Carlos A. Fernandez-Patron Jo-Lynn Yen, Edmonton Rutuja Kadam, Sherwood Park Louis St Laurent Junior/Senior High School Salisbury Composite High School Mentor: Christine A. Webber Mentor: Andrew J. Simmonds UNIVERSITY OF CALGARY Claire Kee, Edmonton Archbishop MacDonald Catholic High School Christopher Aitken, Calgary Mentor: Michele C. Crites Battie Mentor: Stephen B. Wilton Brea Kesslar, Edmonton Edmonton Christian High School Juan (Sebastian) Alvarez, Calgary Mentor: Gary D. Lopaschuk Bishop O’Byrne High School Mentor: Campbell P. Rolian Kylie Kwok, St Albert Paul Kane High School Michelle Chung, Calgary Mentor: Lori J. West Bishop O’Byrne High School Mentor: Herman Barkema

2014-15 ANNUAL REPORT 57 Jameson A. Dundas, Calgary Amelia Srajer, Calgary Rundle College Senior High Mentor: Satish Raj Mentor: Frank van der Meer

Shannon Edie, Calgary Natalie Tai, Calgary Queen Elizabeth High School West Island College Mentor: Brent Edwards Mentor: Subrata Ghosh

Katrine Gillett, Canmore Natalie Williams, Calgary Canmore Collegiate High School Central Memorial High School Mentor: Susan Kutz Mentor: Marie E. Fraser

Sophie Gobeil, Calgary Rebecca Wytsma, Calgary Bishop Carroll High School William Aberhart High School Mentor: Sean P. Dukelow Mentor: Aaron A. Goodarzi

Angie Hu, Calgary Yuwei Xia, Calgary St Francis High School Dr. E.P. Scarlett High School Mentor: Kathryn M. King-Shier Mentor: Careem Faizal

Bryan Ma, Calgary Sophie Zhao, Calgary Western Canada High School Sir Winston Churchill High School Mentor: Matthew T. James Mentor: Naweed I. Syed

Jenice Ma, Calgary UNIVERSITY OF LETHBRIDGE Western Canada High School Mentor: Walter Herzog Eyram A. Asem, Lethbridge Timothy Marino, Calgary Winston Churchill High School Springbank Community High School Mentor: Robbin L. Gibb Mentor: Derek V. Exner Kai Bailey, Lethbridge Mica Pabia, Calgary Chinook High School Bishop McNally High School Mentor: Bryan E. Kolb Mentor: Patricia A. Tang Kate Chua, Lethbridge Andrew Panteluk, Red Deer Catholic Central High School Ecole Secondaire Notre Dame Composite High School Mentor: Robert J. Sutherland Mentor: Marc J. Poulin Grace E. Forster, Lethbridge Danna Pham, Calgary Lethbridge Collegiate Institute Clear Water Academy Mentor: Gerlinde A. Metz Mentor: Herman Barkema Anileen Pageni, Lethbridge Joshua Quan, Calgary Winston Churchill High School Sir Winston Churchill High School Mentor: Ute Kothe Mentor: Tao Dong Daniel Rocca, Lethbridge Miranda C. Schmidt, Airdrie Catholic Central High School Bert Church High School Mentor: Hans-Joachim Wieden Mentor: Karen M. Benzies

58 ALBERTA INNOVATES – HEALTH SOLUTIONS Summer Students Shuo Chen, Medicine & Dentistry Supervisor: Larry Fliegel UNIVERSITY OF ALBERTA Nathan Y. P. Chu, Medicine & Dentistry Raafi Ali, Medicine & Dentistry Supervisor: Joseph Brandwein Supervisor: Vickie E. Baracos Lucas J. Churchill, Medicine & Dentistry Marya Aman, Medicine & Dentistry Supervisor: Eytan Wine Supervisor: David H. Evans Nicholas P. Churchill, Science Colin G. Andrews, Medicine & Dentistry Supervisor: Christine M. Szymanski Supervisor: Hadi Seikaly Quinn Daviduck, Medicine & Dentistry Alexandra Bain, Science Supervisor: Rachel G. Khadaroo Supervisor: Christine M. Szymanski Chad Diederichs, Medicine & Dentistry Ankur Banerjee, Medicine & Dentistry Supervisor: Jacob L. Jaremko Supervisor: David Westaway Kristen Dietrich, Science Meredith Bara, Engineering Supervisor: Frederick Colbourne Supervisor: Warren H. Finlay Victor Do, Medicine & Dentistry Diana Bark, Medicine & Dentistry Supervisor: Jason R. Dyck Supervisor: Adrian Wagg Suraj Sharma Domun, Engineering Michael Bell, Science Supervisor: Hasan Uludag Supervisor: Todd L. Lowary Abdullah Farooq, Science Grace E. Bellerose, Medicine & Dentistry Supervisor: Jonathan J. Dennis Supervisor: Jason P. Acker David Fung, Medicine & Dentistry Michael D. Bildersheim, Medicine & Dentistry Supervisor: Sandra T. Davidge Supervisor: Luis M. Schang Brandon E. Hauer, Science Rebecca N. Burchett, Medicine & Dentistry Supervisor: Clayton T. Dickson Supervisor: Roseline Godbout Jesse Hill, Medicine & Dentistry Sylvia Cao, Science Supervisor: Brian H. Rowe Supervisor: Ted W. Allison Yuhao (Danny) Huang, Medicine & Dentistry Ana Catuneanu, Medicine & Dentistry Supervisor: J. N. Mark Glover Supervisor: Paige Lacy Joshua N. Irwin, Science Calvin J. Chan, Medicine & Dentistry Supervisor: Mario F. Feldman Supervisor: Paul R. Melancon Stephania Irwin, Medicine & Dentistry Charice S. Chan, Medicine & Dentistry Supervisor: M. Joanne Lemieux Supervisor: Adrian Wagg Alexis Katzell, Medicine & Dentistry Christopher J. Chan, Medicine & Dentistry Supervisor: Gregory D. Funk Supervisor: David Westaway Kevin M.W. Khey, Science Lucila R. Chen, Medicine & Dentistry Supervisor: John C. Vederas Supervisor: Christopher McCabe Mary J. Klute, Nursing Patricia A. Chen, Medicine & Dentistry Supervisor: Shannon D. Scott Supervisor: Maya Shmulevitz

2014-15 ANNUAL REPORT 59 Brenda Lam, Medicine & Dentistry Darryl J. Mah, Medicine & Dentistry Supervisor: Benjamen Montpetit Supervisor: Jason R. Dyck

Brendon Lamarche, Medicine & Dentistry Regan S. R. Mah, Medicine & Dentistry Supervisor: Lori J. West Supervisor: Larry Fliegel

Andy Le, Science Tyler R. McDonald, Science Supervisor: Robert E. Campbell Supervisor: John C. Vederas

Kyra J. Lee, Pharmacy and Pharmaceutical Sciences Sae Young (Sally) Moon, Medicine & Dentistry Supervisor: John M. Seubert Supervisor: Christian Beaulieu

Tae Young (Tim) Lee, Medicine & Dentistry Nerissa Nankissoor, Medicine & Dentistry Supervisor: M. Joanne Lemieux Supervisor: Joel B. Dacks

Luke R. Leggo, Rehabilitation Medicine Soumil Narayan, Agricultural, Life & Environmental Sciences Supervisor: Karim Fouad Supervisor: Vera C. Mazurak

Dickson H.H. Leung, Medicine & Dentistry Karl Narvacan, Medicine & Dentistry Supervisor: Carlos A. Fernandez-Patron Supervisor: Christian Beaulieu

Yibo (Teresa) Li, Medicine & Dentistry Jennifer M. Ng, Medicine & Dentistry Supervisor: Rachel G. Khadaroo Supervisor: Ban Chi-Ho Tsui

Brandon Lieu, Rehabilitation Medicine Peter Norris, Medicine & Dentistry Supervisor: Jaynie F. Yang Supervisor: David H. Evans

Isabel Light, Medicine & Dentistry Amarjot K. Padda, Medicine & Dentistry Supervisor: Carmen R. Rasmussen Supervisor: Sunita Vohra

Ying Ling, Medicine & Dentistry Meet Patel, Medicine & Dentistry Supervisor: Peter A. Senior Supervisor: Casey, Joseph R.

Yuejian (Charlotte) Liu, Medicine & Dentistry Amanda Paton, Nursing Supervisor: Gary A. Eitzen Supervisor: Kingston, Dawn

Kaitlyn Lopushinsky, Medicine & Dentistry Amit R.L. Persad, Medicine & Dentistry Supervisor: Lynne-Marie Postovit Supervisor: Roseline Godbout

Jenny W. H. Lou, Physical Education & Recreation Zofia Prus-Czarnecka, Medicine & Dentistry Supervisor: David F. Collins Supervisor: Peter E. Light

Jessica Luc, Medicine & Dentistry Kaylynn Purdy, Medicine & Dentistry Supervisor: Jayan Nagendran Supervisor: Douglas W. Zochodne

Jingyi (Jenny) Ma, Medicine & Dentistry Ali H. Qadri, Medicine & Dentistry Supervisor: Karen J. Goodman Supervisor: Joseph R. Casey

Kelly Y. K. Ma, Medicine & Dentistry Bilal Qarni, Medicine & Dentistry Supervisor: David M. Olson Supervisor: Aminu Bello Nayef Maarouf, Medicine & Dentistry Steven Quan, Pharmacy and Pharmaceutical Sciences Supervisor: Richard A. Rachubinski Supervisor: John M. Seubert

Tanner Mack, Medicine & Dentistry Yasmin Rafiei, Medicine & Dentistry Supervisor: D. Lorne Tyrrell Supervisor: A. M. James Shapiro

60 ALBERTA INNOVATES – HEALTH SOLUTIONS Jahanara Rajwani, School of Public Health Andrew G. Woodman, Medicine & Dentistry Supervisor: Stephanie Yanow Supervisor: Stephane Bourque

Brock Randolph, Medicine & Dentistry Yilun Wu, Medicine & Dentistry Supervisor: Troy A. Baldwin Supervisor: Darren H. Freed

Parnian Riaz, Medicine & Dentistry Andrew Xiao, Medicine & Dentistry Supervisor: Ken S. Butcher Supervisor: J. N. Mark Glover

Stewart R. Rowe, Medicine & Dentistry Zhihao Xu, Medicine & Dentistry Supervisor: Sandra T. Davidge Supervisor: Ronald B. Moore

Bradley Rutherford, Medicine & Dentistry Kelly M. Zerr, Medicine & Dentistry Supervisor: Howard S. Young Supervisor: Joel B. Dacks

Jaskiran K. Sandha, Medicine & Dentistry Rahel T. Zewude, Medicine & Dentistry Supervisor: Darren H. Freed Supervisor: Ken S. Butcher

Julia L. Sawatzky, Medicine & Dentistry Xu Anne Zhang, Medicine & Dentistry Supervisor: Lisa A. Hartling Supervisor: Jack H. Jhamandas

Naveet Sohi, Medicine & Dentistry Kasia Zubkow, Medicine & Dentistry Supervisor: Sanjay Kalra Supervisor: Bradley J. Kerr

Morgan Sosniuk, Medicine & Dentistry UNIVERSITY OF CALGARY Supervisor: Lori J. West

Cole Sugden, Medicine & Dentistry Anish Arora, Cumming School of Medicine Supervisor: Ian R. Winship Supervisor: Naweed I. Syed

Emily Sunwoo, Medicine & Dentistry Rahul K. Arora, Cumming School of Medicine Supervisor: Michael Weinfeld Supervisor: Don Morris

Eszter Szepesvari, Medicine & Dentistry Bryce A.A. Besler, Schulich School of Engineering Supervisor: Ian R. Winship Supervisor: Elise C. Fear

Jeffrey Zhi-Hong Tran, Science Rhiannon E. Brett, Veterinary Medicine Supervisor: Todd L. Lowary Supervisor: Patrick J. Whelan

Calvin Tseng, Medicine & Dentistry Sage A. Brown, Arts Supervisor: Ian M. MacDonald Supervisor: Penny M. Pexman

Vishnu Vasanthan, Medicine & Dentistry William (Cameron) Buie, Cumming School of Medicine Supervisor: Jayan Nagendran Supervisor: Paul L. Beck

Harris C. Wang, Medicine & Dentistry Jessica Cao, Cumming School of Medicine Supervisor: Ian Paterson Supervisor: Wallace K. MacNaughton

Yiqun Wang, Science Stefan Ceklic, Cumming School of Medicine Supervisor: Robert E. Campbell Supervisor: Anthony B. Schryvers

Michael R. Williamson, Science Clement K.O. Chan, Veterinary Medicine Supervisor: Frederick Colbourne Supervisor: James C. Cross

John D. Wink, Medicine & Dentistry Leona Chan, Cumming School of Medicine Supervisor: A. M. James Shapiro Supervisor: Xi-Long Zheng

2014-15 ANNUAL REPORT 61 Dirk A. Chisholm, Cumming School of Medicine Chuyang (Aaron) Lin, Science Supervisor: Brent E. Hagel Supervisor: Joe J. Harrison

Gerard M. Coughlin, Cumming School of Medicine Fangyi Liu, Science Supervisor: Deborah M. Kurrasch Supervisor: Joe J. Harrison

Sharon Feng, Cumming School of Medicine JianRui (Peter) Liu, Cumming School of Medicine Supervisor: Stephen Freedman Supervisor: Don Morris

Chaitanya Gandhi, Cumming School of Medicine Lindsey Logan, Cumming School of Medicine Supervisor: Matthew N. Hill Supervisor: Sean P. Dukelow

Brianna M. Ghali, Kinesiology Trevor Low, Cumming School of Medicine Supervisor: Carolyn A. Emery Supervisor: Brian L. Brooks

Jill Girgulis, Cumming School of Medicine Keon Ma, Cumming School of Medicine Supervisor: Rajiv Midha Supervisor: Frank P. MacMaster

Katherine Girgulis, Cumming School of Medicine Ajay Mahajan, Cumming School of Medicine Supervisor: Karen M. Barlow Supervisor: Philip A. Barber

Jordan N. Haidey, Veterinary Medicine Getanshu Malik, Cumming School of Medicine Supervisor: Tuan Trang Supervisor: Henry J. Duff

Alexander Harris, Cumming School of Medicine Lorenzo Marcil, Cumming School of Medicine Supervisor: Paul L. Beck Supervisor: Karen M. Barlow

Zachary Hong, Cumming School of Medicine Madison Milne-Ives, Cumming School of Medicine Supervisor: Shelagh B. Coutts Supervisor: Paolo Federico

Rhys P. Johnson, Cumming School of Medicine Daniel A. Moussienko, Cumming School of Medicine Supervisor: Christine M. Friedenreich Supervisor: Susan P. Lees-Miller Anna Kim, Cumming School of Medicine Sujay Nagaraj, Cumming School of Medicine Supervisor: Sarah J. Childs Supervisor: Cheryl Barnabe

Si Yong Kim, Kinesiology Julie A. Osgood, Cumming School of Medicine Supervisor: Walter Herzog Supervisor: Jillian S. Parboosingh

Aaron J. Lanz, Cumming School of Medicine Ayodele E. Oyeyemi, Science Supervisor: Jaideep S. Bains Supervisor: Andre G. Buret

Keith C. K. Lau, Cumming School of Medicine Kanwar G.S. Pannu, Cumming School of Medicine Supervisor: Douglas J. Mahoney Supervisor: Eric W. Smith

Miranda C. Lee, Science Daniel S. Park, Cumming School of Medicine Supervisor: Sergei Y. Noskov Supervisor: Paul W. M. Fedak

Danielle C. Lefebvre, Arts John SeiYoung Park, Cumming School of Medicine Supervisor: Vina M. Goghari Supervisor: Todd J. Anderson

Katherine Li, Cumming School of Medicine Suhyeon Park, Cumming School of Medicine Supervisor: Gerald W. Zamponi Supervisor: Ki-Young Lee

Jenny Q. Liao, Cumming School of Medicine Joey Poon, Cumming School of Medicine Supervisor: Gregory Cairncross Supervisor: Derek M. McKay

62 ALBERTA INNOVATES – HEALTH SOLUTIONS Joey C. Prisnie, Cumming School of Medicine Felix Wei, Cumming School of Medicine Supervisor: Nathalie Jette Supervisor: C. Adam Kirton

Kristina Quan, Cumming School of Medicine Alexis T. Wilson, Cumming School of Medicine Supervisor: David A. Hart Supervisor: Michael D. Hill

Jung Kuo Ra, Veterinary Medicine Alexander Wong, Cumming School of Medicine Supervisor: M. Faizal Abdul-Careem Supervisor: Derek V. Exner

Elliott M. Reichardt, Cumming School of Medicine Sydney Yee, Cumming School of Medicine Supervisor: Bryan G. Yipp Supervisor: Eric W. Smith

Mu Qing (Austin) Ren, Cumming School of Medicine Aran Yukseloglu, Cumming School of Medicine Supervisor: Richard Leigh Supervisor: Peter K. Stys

Madison A. Riddell, Cumming School of Medicine Yiming Michael Zhu, Cumming School of Medicine Supervisor: C. Adam Kirton Supervisor: Todd J. Anderson

Paul Riek, Kinesiology Jeremy H. Zuo, Cumming School of Medicine Supervisor: Walter Herzog Supervisor: Franciscus A. van der Hoorn

Prajay Shah, Veterinary Medicine UNIVERSITY OF LETHBRIDGE Supervisor: Jeffrey A. Biernaskie

Sarthak Sinha, Veterinary Medicine Alycia N. Amatto, Arts & Science Supervisor: Jeffrey A. Biernaskie Supervisor: Ute Kothe

Philip J. Surmanowicz, Cumming School of Medicine Lindsay Amatto, Arts & Science Supervisor: Christopher H. Mody Supervisor: Robbin L. Gibb

Weiwen (David) Tang, Cumming School of Medicine Cecilia A. Badenhorst, Arts & Science Supervisor: Voon Wee Yong Supervisor: Aaron Gruber

Leonie C. A. Tesorero, Cumming School of Medicine Ana Canabrava Carvalho, Arts & Science Supervisor: William A. Ghali Supervisor: Bryan E. Kolb

Siobhan K. Thornton, Cumming School of Medicine Nathan P. B. Grigg, Arts & Science Supervisor: Deborah M. Dewey Supervisor: Andrew N. Iwaniuk

Michael R. Tom, Cumming School of Medicine Megan S. Malach, Arts & Science Supervisor: Subrata Ghosh Supervisor: Olga Kovalchuk

Drayton Trumble, Cumming School of Medicine Janet Poplawski, Arts & Science Supervisor: Eddy S. Lang Supervisor: Gerlinde A. Metz

Mohit Vohra, Cumming School of Medicine Amanda M. Weiler, Arts & Science Supervisor: Rajiv Midha Supervisor: Gerlinde A. Metz

Gabrielle O. Wagner, Cumming School of Medicine Lauren Williams, Arts & Science Supervisor: Michael D. Hill Supervisor: Andrew N. Iwaniuk

Miranda Wan, Cumming School of Medicine Supervisor: Gerald W. Zamponi

Yundi Wang, Cumming School of Medicine Supervisor: Sui R. (Wayne) Chen

2014-15 ANNUAL REPORT 63

ALBERTA INNOVATES - HEALTH SOLUTIONS Suite 1500, 10104 - 103 Avenue Edmonton, Alberta T5J 4A7

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